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1 Fallot or pulmonary atresia with ventricular septal defect.
2 th the pathogenesis of atrioventricular (AV) septal defect.
3 tricuspid atresia and large secundum atrial septal defect.
4 oplasia, hypertrabeculation, and ventricular septal defect.
5 uble-outlet right ventricle, and ventricular septal defect.
6 function, and had no evidence of ventricular septal defect.
7 ight ventricle with a concurrent ventricular septal defect.
8 birth with lung hypoplasia and a ventricular septal defect.
9 other cardiac defects including ventricular septal defect.
10 arge family with dominantly inherited atrial septal defect.
11 eptum and 298 (38%) for TGA with ventricular septal defect.
12 onding to surgical closure of a large atrial septal defect.
13 pproaches for simple lesions, such as atrial septal defect.
14 tium primum defect, a hallmark feature of AV septal defects.
15 humans, including dilated cardiomyopathy and septal defects.
16 iciency in mice could cause atrioventricular septal defects.
17 at different loci for atrial and ventricular septal defects.
18 7Bl/6 frequently have atrial and ventricular septal defects.
19 defects and C57Bl/6 to muscular ventricular septal defects.
20 uble outlet right ventricles and ventricular septal defects.
21 ction affect muscular ventricular and atrial septal defects.
22 ular septum and display profound ventricular septal defects.
23 e with thin ventricular wall and ventricular septal defects.
24 ed with the pathogenesis of atrioventricular septal defects.
25 , pulmonary artery stenosis, and ventricular septal defects.
26 rterial trunk and perimembranous ventricular septal defects.
27 s and between ozone and isolated ventricular septal defects.
28 ventricular (VSD) or atrioventricular (AVSD) septal defects.
29 ntribute to human congenital heart valve and septal defects.
30 esponsible for a subset of syndromic cardiac septal defects.
31 issense mutations that cause similar cardiac septal defects.
32 ionally inactive and segregated with cardiac septal defects.
33 or (CHF)1Hey2 gene show isolated ventricular septal defects.
34 for percutaneous closure of secundum atrial septal defects.
35 w tract alignment and membranous ventricular septal defects.
36 pecific defects, prevalence was greatest for septal defects.
37 n and between sertraline use and ventricular septal defects.
38 yndrome but inversely associated with atrial septal defects.
39 d efficacy of device closure of large atrial septal defects.
40 and perimembranous and muscular ventricular septal defects.
42 interval, -0.87 to -0.10); major ventricular septal defects, -0.41 (95% confidence interval, -0.52 to
43 association was significant for ventricular septal defects (1.1% vs 0.6%; P = .001) and other CHDs (
44 premature CAD (OR for CoA versus ventricular septal defect, 1.44; 95% CI, 0.79-2.64) after adjustment
45 9 kindreds with familial CHD, 4 with atrial septal defects, 2 with patent ductus arteriosus, 2 with
46 iagnoses included tetralogy of Fallot (51%), septal defects (20%), (congenitally corrected) transposi
47 tricular septal defects (22/47, 47%), atrial septal defects (20/47, 43%), patent ductus arteriosus (1
48 rdiovascular anomalies, of which ventricular septal defects (22/47, 47%), atrial septal defects (20/4
49 400 patients, 154 (38.3%) with a ventricular septal defect, 238 (59.5%) with an intact septum, and 9
51 ticularly high for isolated atrioventricular septal defects (4 of 5 [80%]) and laterality defects (7
52 the great arteries (8%), ventricular/atrial septal defects (8%), left ventricular outflow obstructio
55 ural crest such as cleft palate, ventricular septal defect, abnormal development of hypoglossal nerve
56 ng aortic coarctation, ventricular or atrial septal defect, abnormal mitral valve, aortic root dilati
57 highest risk of IE in comparison with atrial septal defects (adjusted rate ratio, 95% confidence inte
58 ion, with d-TGA, with or without ventricular septal defects, admitted to our institution at 5 days of
59 right ventricle, and atrial and ventricular septal defects, all occurring with variable penetrance.
60 -) embryos revealed a membranous ventricular septal defect and an abnormal nodule of cartilage within
61 ulting from a profound subaortic ventricular septal defect and associated malalignment of the outflow
62 that confer greater susceptibility to atrial septal defect and atrioventricular septal defects and C5
64 icus, congestive heart failure due to atrial septal defect and hypernatremic dehydration due to diabe
65 ovascular development, including ventricular septal defect and non-compaction, as well as outflow tra
67 iduals with DS and complete atrioventricular septal defect and sequenced 2 candidate genes for CHD: C
68 igh penetrance, large membranous ventricular septal defects and a bifid cardiac apex, and less freque
69 ryonic death, but does result in ventricular septal defects and a low incidence of semilunar valve de
71 though human mutation of NKX2-5 is linked to septal defects and atrioventricular conduction abnormali
72 between carbon monoxide and isolated atrial septal defects and between ozone and isolated ventricula
74 nt in magnitude were detected between atrial septal defects and bromoform (aOR = 1.56; 95% CI: 1.01,
75 to atrial septal defect and atrioventricular septal defects and C57Bl/6 to muscular ventricular septa
79 xclusively to Lipid II binding, which causes septal defects and catastrophic cell envelope damage.
80 ts with CHD7 mutations, but atrioventricular septal defects and conotruncal heart defects are over-re
82 , p.G115W, was identified in familial atrial septal defects and demonstrated decreased transactivatio
83 tion resulted in atrial and atrioventricular septal defects and hypoplasia of the developing DMP.
84 ct device for use in multifenestrated atrial septal defects and the fenestrated atrial septal defect
86 cription factor gene, cause atrioventricular septal defects and valve abnormalities by disrupting a s
87 tidiastole of coronary heart disease, atrial septal defect, and atrial fibrillation are made, and the
91 malities of the tricuspid valve, ventricular septal defect, and pulmonary stenosis, occur in the majo
92 yndrome of progressive RCM, atrioventricular septal defects, and a high prevalence of atrial fibrilla
93 d myocardium, ventricular and aortopulmonary septal defects, and abnormal smooth muscle development.
97 embryos had a double outlet RV, ventricular septal defects, and hypertrophic myopathy, with near obl
100 excluding ventricular septal defects, atrial septal defects, and pulmonary valve stenosis) occurred i
104 aOR = 1.28; 95% CI: 1.03, 1.61), ventricular septal defect (aOR = 1.19; 95% CI: 1.00, 1.43), and tetr
106 sitively associated with the risks of atrial septal defect (aORs ranging from 1.29 to 2.17), patent d
107 ollutants and daily risks of secundum atrial septal defect, aortic coarctation, hypoplastic left hear
109 Conotruncal defects and atrioventricular septal defects are over-represented in patients with CHD
113 s (aRR, 0.85; 95% CI, 0.75-0.96), and atrial septal defects (aRR, 0.82; 95% CI, 0.69-0.95) but not se
114 (aRR, 0.77; 95% CI, 0.61-0.96), ventricular septal defects (aRR, 0.85; 95% CI, 0.75-0.96), and atria
115 n a cohort of patients with atrioventricular septal defects as a part of Ellis van Creveld syndrome (
116 d male lethal condition encompassing cardiac septal defects, as well as ocular and dental anomalies.
117 eft-sided lesions (n = 160), secundum atrial septal defect (ASD) (n = 71), and Ebstein's malformation
119 We compared administrative data for atrial septal defect (ASD) and ventricular septal defect (VSD)
121 (7)) with the risk of ostium secundum atrial septal defect (ASD) in the discovery cohort (N = 340 cas
122 n cause an autosomal dominant form of atrial septal defect (ASD), whereas others have identified muta
124 solated procedures: device closure of atrial septal defect (ASD); device closure of patent ductus art
125 permanent synthetic implants to close atrial septal defects (ASD) and patent foramen ovale (PFO) has
126 anscatheter closures of secundum type atrial septal defects (ASD) and to assess ASD size and changes
127 e embryo and persistent ostium primum atrial septal defects (ASD) in approximately 20% of adults.
128 Transcatheter closure of secundum atrial septal defects (ASD) using the Amplatzer septal occluder
135 de Lange syndrome-associated secundum atrial septal defects (ASDs) caused by NIPBL mutations, underta
137 transposition of great vessels, ventricular septal defect, atrial septal defect, tetralogy of Fallot
138 onchromosomal CHD (ie, excluding ventricular septal defects, atrial septal defects, and pulmonary val
139 f right dominant unbalanced atrioventricular septal defect (AVSD) remains challenging because unbalan
147 years) with large, isolated, secundum atrial septal defects (balloon-stretched diameter >/=34 mm in a
149 defect (SVASD) differs from secundum atrial septal defect by its atrial septal location and its asso
150 ranscatheter closure of muscular ventricular septal defects; (c) the transcatheter closure of perimem
153 ients (6%) in the pitavastatin group (atrial septal defect, chronic obstructive pulmonary disease, ch
154 ocedure (9%), patent foramen ovale or atrial septal defect closure (23%), cardiac metastasectomies or
155 with death after postinfarction ventricular septal defect closure included the following: age (hazar
158 equent concomitant procedures such as atrial septal defect closure, arrhythmia surgery (the maze proc
159 scatheter valve replacements and ventricular septal defect closures have already been performed in ch
160 The associations with major ventricular septal defects, common arterial trunk, and anomalous pul
161 nital cardiac malformations like ventricular septal defects, common atrioventricular canal and double
162 ar septal defect, perimembranous ventricular septal defect, conotruncal defects, left ventricular out
163 analyses of probands with heterotaxy, atrial septal defects, conotruncal, and left ventricular outflo
164 r hypertrophy, overriding aorta, ventricular septal defects, coronary vessel abnormalities and valve
165 lities include overriding aorta, ventricular septal defects, cranial nerve, and craniofacial skeletal
166 theter closure of perimembranous ventricular septal defects; (d) the placement of bioprosthetic valve
168 atzer Ductal Occluder, the cribriform atrial septal defect device for use in multifenestrated atrial
170 livery system for the membranous ventricular septal defect device that is aimed to overcome the diffi
173 MII-B by 80% results in cardiac (ventricular septal defect, double outlet of the right ventricle) and
174 1-expressing progenitors display ventricular septal defects, double outlet right ventricle, semilunar
175 ardiac anomalies, including atrioventricular septal defects, Ebstein malformation of the tricuspid va
176 ive procedure to create or enlarge an atrial septal defect for the treatment of neonates with hypopla
178 perative urgency and postinfarct ventricular septal defect, have been relatively stable over time, wh
179 s, congenital diaphragmatic hernias, cardiac septal defects, hearing loss and autistic and self-injur
180 omen had significantly higher ORs for atrial septal defects, hypoplastic left heart syndrome, aortic
181 1, which is associated with atrioventricular septal defect in people with or without DS, and HEY2, wh
182 openia, intermittent neutropenia, and atrial septal defects in 3 members of a consanguineous kindred.
184 ion of both miRNAs causes lethal ventricular-septal defects in approximately half of double-mutant em
185 with ventricular hypoplasia and ventricular septal defects in beta-myosin heavy chain-miR-195 transg
186 hysiology, treatment, and outcomes of atrial septal defects in children and adult patients in whom th
187 ch is demonstrated in characterizing cardiac septal defects in conditional mutant embryos lacking the
191 rged valve cusps, bicuspid aortic valve, and septal defects, indicating that endocardial Jag1 to Notc
192 aneous closure of postinfarction ventricular septal defect is a reasonably effective treatment for th
195 mutation in TLL1 was identified in an atrial septal defects kindred and is predicted to affect the en
196 y increased by the presence of a ventricular septal defect, left ventricular outflow obstruction, sur
197 repaired "simple" lesions such as an atrial septal defect may not have normal survival if they are r
199 s underwent repair of a secundum-type atrial septal defect (n=12) or patent foramen ovale (n=5) by a
200 o detected by micro-CT were atrioventricular septal defects (n=22), tricuspid hypoplasia/atresia (n=1
202 offspring with a perimembranous ventricular septal defect (odds ratio = 3.23, 95% confidence interva
203 and sulfur dioxide and isolated ventricular septal defects (odds ratio = 2.16, 95% confidence interv
204 in aerodynamic diameter and isolated atrial septal defects (odds ratio = 2.27, 95% confidence interv
205 95% CI, 1.6 to 20.7; 3 exposed subjects) and septal defects (odds ratio, 2.0; 95% CI, 1.2 to 4.0; 13
206 ance, such as cleft palate, choanal atresia, septal defects of the heart, haemorrhages, prenatal deat
207 We identified a new locus linked with atrial septal defect on chromosome 14q12 in a large family with
209 ocardial cushions accompanied by ventricular septal defects, outflow tract abnormalities and atrio-ve
210 eft superior vena cava (P=0.85), ventricular septal defect (P=0.12), and bicuspid aortic valve (P=0.1
212 annulus, (1B) ventriculotomy-to-ventricular septal defect patch, (2) ventriculotomy-to-pulmonary ann
213 nnulus, (3) pulmonary annulus-to-ventricular septal defect patch, and (4) ventricular septal defect p
216 tflow tract (99%) or the site of ventricular septal defect patching (98%) and in the inferior RV inse
217 nes relevant for atrial and atrioventricular septal defects, patent ductus arteriosus, bicuspid aorti
218 the transcatheter closure of secundum atrial septal defects, patent foramen ovale, patent ductus arte
220 te GATA4 as a genetic cause of human cardiac septal defects, perhaps through its interaction with TBX
221 rt chambers, interatrial or interventricular septal defects, pericardium, and site and size of the gr
222 of the great arteries, muscular ventricular septal defect, perimembranous ventricular septal defect,
223 defects in the right ventricle, ventricular septal defect, persistent truncus arteriosus, reduced my
224 uding abnormalities of other cardiac valves, septal defects, persistent left superior vena cava, and
225 mily with forelimb anomalies and ventricular septal defects, phenotypes similar to Holt-Oram syndrome
226 erative repair of perimembranous ventricular septal defect (PMVSD) in a large multi-institutional dat
227 theter closure of perimembranous ventricular septal defects (PmVSDs) using the new Amplatzer Membrano
228 etween the use of sertraline and ventricular septal defects (relative risk, 1.04; 95% CI, 0.76 to 1.4
230 that haploinsufficient versican mice display septal defects resembling those seen in Crtl1(-/-) embry
231 netically interact in vivo: atrioventricular septal defects result from endothelial-specific Gata4 an
233 e TARP syndrome, talipes equinovarus, atrial septal defect, Robin sequence, and persistent left super
234 , but not a mutation causing secundum atrial septal defects (S52F), demonstrated impaired protein int
235 eta led to abnormal heart shape, ventricular septal defects, severe growth retardation, and postnatal
236 l period as well as for muscular ventricular septal defects should be the transcatheter approach.
238 c NSML SHP2 expression developed ventricular septal defects, suggesting that NSML-associated mutation
239 or = 2 loci influence membranous ventricular septal defect susceptibility, whereas > or = loci and at
241 ith IAA associated with sinus venosus atrial septal defect (SVD) and partial anomalous pulmonary veno
242 included bifid atrial appendage, ventricular septal defect, tetralogy of Fallot (TOF), and an aortic
243 urgery for atrial septal defect, ventricular septal defect, tetralogy of Fallot, and transposition of
244 t vessels, ventricular septal defect, atrial septal defect, tetralogy of Fallot, coarctation of the a
245 with CHD (atrial septal defect, ventricular septal defect, tetralogy of Fallot, Ebstein anomaly, tra
246 tools, specifically in patients with atrial septal defects, tetralogy of Fallot, single ventricle ph
247 (TGA/IVS, n = 79, 63%), TGA with ventricular septal defect (TGA/VSD, n = 37, 30%), and Taussig Bing A
248 -long-term data for device closure of atrial septal defects, the incidence of late cardiac erosions,
249 ents with isolated atrial and/or ventricular septal defects, the predominant cardiac defects of the H
250 for Percutaneous Closure of Secundum Atrial Septal Defects; this study was approved by the Food and
251 the pilot in vivo study to create an atrial septal defect through the use of extracardiac applicatio
252 nts without prior diagnosis of PFO or atrial septal defect undergoing surgery at the Cleveland Clinic
253 and creation or enlargement of a ventricular septal defect using stents are potential therapeutic opt
255 device closure of perimembranous ventricular septal defects using the Amplatzer membranous ventricula
257 2 cohorts: (1) all patients with CHD (atrial septal defect, ventricular septal defect, tetralogy of F
258 in the human proband, as well as ventricular septal defect (VSD) and double-outlet right ventricle (D
260 r atrial septal defect (ASD) and ventricular septal defect (VSD) surgeries in children 2 months to 19
261 rdiac morphogenesis, including a ventricular septal defect (VSD), abnormal formation of the aortic an
262 erved an increased risk of CHDs, ventricular septal defect (VSD), and tetralogy of fallot (TF) with i
263 g double-outlet right ventricle, ventricular septal defect (VSD), atrioventricular (AV) cushion defec
264 ith intact ventricular septum or ventricular septal defect (VSD), including double-outlet right ventr
265 ongenital heart disease, such as ventricular septal defect (VSD), myocardium noncompaction, and ventr
266 utlet right ventricle (DORV) and ventricular septal defect (VSD), similar to defects observed when ap
273 ntal factors on the incidence of ventricular septal defects (VSDs) caused by a heterozygous Nkx2-5 kn
274 e closure of congenital muscular ventricular septal defects (VSDs) using the new Amplatzer mVSD occlu
276 kinking with 100% penetrance and ventricular septal defects (VSDs) with ~15% penetrance; Fz2(+/-);Fz7
277 fects within it, termed muscular ventricular septal defects (VSDs), are common, yet less is known abo
283 fic birth defects, only that for ventricular septal defects was significantly elevated, with an expos
285 Under real-time ultrasound guidance, atrial septal defects were successfully created with extracardi
286 , whereas outflow tract and atrioventricular septal defects were the most prevalent complex CHD.
289 luding cardiac noncompaction and ventricular septal defect, which phenocopies 1p36 deletion syndrome
291 , ventricular noncompaction, and ventricular septal defects, while, in the postnatal cardiomyocyte, Q
292 tients with CoA and those with a ventricular septal defect, who are not known to be at increased risk
296 ethal and had complete atrioventricular (AV) septal defects with a single AV valve and myocardial thi
297 ac ventricular wall thinning and ventricular septal defects with double outlet right ventricle or ove
298 odel a specific subtype of atrio-ventricular septal defects with exclusive ventricular shunting and d
300 erior cervical vertebral synostosis, cardiac septal defects with valve dysplasia, and deafness with i
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