ライフサイエンスコーパス: septation

1 phenotypic abnormalities, including cardiac septation.

2 be a SHF Tbx5-Hh network required for atrial septation.

3 displayed more defective growth and aberrant septation.

4 urin complex in regulating hyphal growth and septation.

5 networking and downstream targets for atrial septation.

6 d with claudins in epithelia at the point of septation.

7 e digested, allowing Bdellovibrio growth and septation.

8 of large axial filaments that interfere with septation.

9 rated by FtsZ, which forms a Z-ring to drive septation.

10 region, which segregates immediately before septation.

11 ure of cardiac outflow tract and ventricular septation.

12 gle mispatterned ventricular chamber lacking septation.

13 morphogenesis, indicating a primary role for septation.

14 ed for vegetative growth but only for timely septation.

15 entity, indicating a requirement for Tbx5 in septation.

16 1 in the second heart field (SHF) for atrial septation.

17 equired in the pulmonary endoderm for atrial septation.

18 y also results in the failure of cardiac OFT septation.

19 have contributed to the evolution of cardiac septation.

20 eing synthesized and rapidly degraded during septation.

21 ly synthesized septal PG was degraded during septation.

22 substantial contribution to atrioventricular septation.

23 ze PG degradation during cell elongation and septation.

24 hymal structure involved in atrioventricular septation.

25 tin landscape of endocardial lineages during septation.

26 in cushion/valve remodeling and ventricular septation.

27 th other than those strictly associated with septation.

28 us region, leading to defects in aortic arch septation.

29 es, all of which are required for normal OFT septation.

30 (CNCCs), are crucial for OFT development and septation.

31 , simultaneous with the evolution of cardiac septation.

32 g migration, leading to a failure of the OFT septation.

33 entral and dorsal outflow cushions before AP septation.

34 pharyngeal endoderm regulates outflow tract septation.

35 n mother cell and prespore immediately after septation.

36 d cell migration genes that are critical for septation.

37 mental control of chromosome replication and septation.

38 stations of MFS, including impaired alveolar septation.

39 ring, and plays an essential role in fungal septation.

40 ntial for outflow tract and atrioventricular septation.

41 gnaling plays a non-autonomous role in digit septation.

42 ation-associated chromosome condensation and septation.

43 bstantial levels in mutants blocked in polar septation.

44 chial-arch arteries (BAAs) and defective OFT septation.

45 present a fully penetrant failure in cloacal septation.

46 roliferation, and lack of proper ventricular septation.

47 eration with Bmp7, has a central role in OFT septation.

48 otruncal cushion formation and outflow tract septation.

49 ocardium directly mediating atrioventricular septation.

50 the chromosome close to the cell pole before septation.

51 dent manner and splits into two rings during septation.

52 developmental impairment of distal alveolar septation.

53 formation of a contractile ring at sites of septation.

54 que perineal structures derived from cloacal septation.

55 wth poles of both siblings immediately after septation.

56 a small subset of mitotic genes involved in septation.

57 he actomyosin ring, and thus promotes medial septation.

58 ricular, outflow tract and aortico-pulmonary septation.

59 tion related to structures formed by cloacal septation.

60 dinating their expression during sporulation septation.

61 cardial thickness at E11.5, prior to cardiac septation.

62 division site and may mark previous sites of septation.

63 to ensure DNA is properly segregated before septation.

64 localization in the longest cells undergoing septation.

65 etic role in fungal cell wall biogenesis and septation.

66 the endocardium is required for ventricular septation.

67 the cardiac valves and for complete cardiac septation.

68 ts of daptomycin on cell wall morphology and septation.

69 loating echoes and thin, incomplete internal septations.

70 %; 95% confidence interval [CI]: 20, 30) had septations.

71 sion without any solid components, debris or septations.

72 velopment: (1) outflow tract development and septation, (2) tissue remodeling events required for car

73 , or with a nodule or multiple thin or thick septations (60%-100%).

74 Loculations (84.2 %) and septations (63.2 %) were the most common radiologic find

75 morrhagic (59%) and those with a single thin septation (67%); 31% of cysts measuring 1-7 cm in postme

76 ortened cardiac outflow tract with defective septation, a process known to require neural crest cells

77 efects, characterized by disrupted secondary septation, abnormal alveolar epithelial cell differentia

78 An unanswered question is how polar septation activates a transcription factor (sigma(F)) se

79 rdial cells derived from the AHF to complete septation after cushion formation.

80 Mig-6(-/-) lungs (E15.5-P3) revealed reduced septation, airway over-branching, alveolar type II cell

81 mbly and sometimes even ring contraction and septation, all during interphase.

82 near heart tube, through complex looping and septation, all the while increasing in mass to provide t

83 heory that as alveoli form through secondary septation, alveolar flow becomes chaotic and chaotic mix

84 Namely, at around the completion of septation, an immature base-to-apex sequence of ventricu

85 Later, during septation and abscission, a second GEF-independent mecha

86 th clearing chromosomal DNA from the site of septation and also acts to position the dif sites for re

87 deficiency results in both impaired alveolar septation and altered morphology of the pulmonary neuroe

88 letion mutant exhibits irregular sporulation septation and altered spore shape, suggesting that SspA

89 Thus, it is possible that ventricular septation and appropriate outflow tract alignment is dep

90 e essential functions of alpha(1-3)glucan in septation and cell separation.

91 hB receptors impairs morphogenetic cell-cell septation and closure events during development of the e

92 egative regulators of the SIN suppressed the septation and conidiation phenotypes due to the loss of

93 The MOBA protein was required for septation and conidiation, but was not essential for hyp

94 ated with the SPB and is required for timely septation and conidiation.

95 eraction against the SIN pathway to regulate septation and conidiation.

96 rdiac morphogenesis, including outflow tract septation and cushion defects, a thin ventricular myocar

97 IcsA localization is independent of the cell septation and cytokinesis proteins FtsQ and FtsEX.

98 ay a central role in regulating the onset of septation and cytokinesis.

99 totic gene transcription and passage through septation and cytokinesis.

100 roliferation, correlating with inhibition of septation and developmental emphysema.

101 urs, which had nuclear pleomorphism, fibrous septation and increased galectin-3 expression, consisten

102 orulation, plasmid segregation occurs before septation and independently of the DNA translocase SpoII

103 cushions is essential for proper ventricular septation and morphogenesis of the mature mitral and tri

104 F) are required for OFT and atrioventricular septation and OFT alignment.

105 rotein, yielded cells with strong defects in septation and polarity respectively.

106 t interact with TBX20 to orchestrate cardiac septation and provides insight into the chromatin landsc

107 s, epithelial cell differentiation, alveolar septation and regulation of alveolar homeostasis.

108 s to the contractile actin ring early during septation and remains at the centre of the mature septum

109 tilaginous structures, cardiac outflow tract septation and thymic and dorsal root ganglia development

110 SftA and SpoIIIE act at different stages of septation and together they ensure maximum fidelity in c

111 V) junction plays a critical role in chamber septation and transmission of cardiac conduction pulses.

112 Proper septation and valvulogenesis during cardiogenesis depend

113 Internal septations and loculations on radiologic examinations sh

114 (SIN) triggers actomyosin ring constriction, septation, and cell division.

115 that triggers actomyosin ring constriction, septation, and cell division.

116 ins at a very early stage, culminates during septation, and decays after division is completed.

117 ocal epithelial stromal signaling, urorectal septation, and modeling of the external genitalia; and i

118 itylation results in defects in cell growth, septation, and nuclear structure, phenotypes not observe

119 these sites is independent of FtsZ, MinCDE, septation, and nucleoid occlusion, indicating that posit

120 on, outflow tract (OFT) and atrioventricular septation, and OFT alignment.

121 ivision septum, promoting ring constriction, septation, and subsequent cell separation following ring

122 ity, presence of rim enhancement or internal septations, and the shape of the contrast material kinet

123 f Gram-negative bacteria is recruited to the septation apparatus during cell division where it is inv

124 We conclude that the septation apparatus, composed of septins, contractile ri

125 tially assembled in a single ring but during septation appeared in the cleavage furrow, forming a was

126 g is identified in tracheoesophageal foregut septation, as animals lacking the cytoplasmic domain of

127 Age, cyst size, and cyst septation at presentation were not predictive of growth.

128 and ring contraction occurs concomitant with septation at the end of anaphase.

129 After septation, Bdellovibrio flagellar motility resumes insid

130 clin-dependent kinase (CDK) and the onset of septation, before G1-CDK can be reactivated and drive re

131 he RA receptor-deficient background restores septation but does not rescue alignment defects, indicat

132 TA4 and TBX5 is important for normal cardiac septation, but the underlying molecular mechanisms are n

133 th muscle from the secondary heart field and septation by cardiac neural crest cells.

134 Regulation of septation by PhoQ/PhoP may protect cells from antimicrob

135 Shh directs cloacal septation by promoting cell proliferation in adjacent ur

136 ise), and FCPL-specific (ie, size, location, septation, calcification, mural nodularity, pancreatic d

137 activity, which could arise from asymmetric septation, can achieve the all-or-nothing response in si

138 ight chamber specification, cardiac looping, septation, cardiac myocyte differentiation, and endocard

139 Both myoB and myoE are necessary for proper septation, conidiation, and conidial germination, but on

140 mutants, exhibited defects in cell shape and septation, consistent with the idea that the availabilit

141 ial growth in broth culture; however, normal septation could be restored if mutant cells were cocultu

142 ce despite the pronounced exponential growth septation defect.

143 result in potentially fatal atrioventricular septation defects (AVSD).

144 nd heart field (SHF) and heart outflow tract septation defects are combined, although the mechanistic

145 thogenic pathway when second heart field and septation defects are coupled.

146 ydrolase NamA and demonstrate that bacterial septation defects associated with a loss of NamA are fun

147 velopment results in outflow and ventricular septation defects commonly observed in congenital heart

148 shion morphology that preceded a spectrum of septation defects from double outlet right ventricle to

149 ion in the myocardium contributes to cardiac septation defects in humans.

150 after neural tube closure results in severe septation defects in the chick, reminiscent of human bir

151 xpression of active Rho4 or Eng1 rescues the septation defects of mutants containing gef3.

152 ced cell proliferation, and atrioventricular septation defects similar to Gata4;Tbx5 compound heteroz

153 enes secA2 mutants form rough colonies, have septation defects, are impaired for swarming motility, a

154 ephalic/carotid artery aneurysms and cardiac septation defects, but developed extensive and apparentl

155 resulted in interventricular septal chamber septation defects, suggesting that TGFbeta superfamily s

156 fects, indicating that excess TGFbeta causes septation defects.

157 ment into the OFT cushions, resulting in OFT septation defects.

158 bution of CnaA and CnaB to hyphal growth and septation, DeltacnaB and DeltacnaADeltacnaB strains of A

159 mbryos display significant rescue of cardiac septation, demonstrating that disruption of this Pbx1-Pa

160 genetic imbalance is unlikely to affect the septation-dependent release of sigmaF.

161 Thus, the position of oriC after septation determines which cell will receive the chromos

162 t during mitosis in a single ring and during septation developed into double rings that did not contr

163 e in the context of the evolution of cardiac septation: do they possess a single ventricular chamber

164 sL and DivIC are not absolutely required for septation during growth and sporulation.

165 e pharyngeal arch arteries and outflow tract septation during heart development, but the lineage spec

166 artery remodeling and cardiac outflow tract septation during vertebrate development.

167 lutamide-treated males does not undergo this septation event.

168 novel role for FtsK in linking cell envelope septation events and yields further evidence for FtsK as

169 e to the other, MinD helps to block unwanted septation events at the poles.

170 E. coli is specifically induced by aberrant septation events caused by mis-oriented Z rings and not

171 enesis, after which it undergoes a series of septation events leading to the formation of the anal ca

172 ays originated from the remnants of abnormal septation events, cementing the relationship between abe

173 Later during aorticopulmonary septation, excessive proliferation in the OFT cushion me

174 Moreover, defects in cell septation, exocytosis, and endocytosis in sec3 mutant st

175 tenuation, including abnormalities of atrial septation, extracellular matrix restriction, relative at

176 ausing severe OFT cushion hypoplasia and OFT septation failure.

177 ring that provides membrane tethering to the septation FtsZ protein, has been incorporated in single

178 ring that provides membrane tethering to the septation FtsZ protein.

179 ons with thick indistinct walls and/or thick septations (> or =0.5 mm), intracystic masses, and predo

180 e, placental labyrinth morphology, lung lobe septation, hair growth, and vascularization of kidney gl

181 contribution of extracardiac cells to atrial septation has recently been recognized.

182 is largely dispensable for ingression; once septation has started, cleavage can continue in the abse

183 utflow and inflow tracts, defects in cardiac septation, heart position, as well as abnormal ventricul

184 d in the Acvr1 locus only partially restored septation in Acvr1 mutants.

185 indicate that in addition to nucleating cell septation in E. coli, FtsZ can direct the insertion of n

186 s 511 and 521, is essential for normal lobar septation in early lung development and normal alveoliza

187 Septation in Fgcdc14 was reduced and hyphal compartments

188 x and activates Rho4 GTPase as a Rho GEF for septation in fission yeast.

189 d in the second heart field (SHF) for atrial septation in mice.

190 trol great-artery patterning and cardiac OFT septation in mice.

191 Mitotic exit in Saccharomyces cerevisiae and septation in Schizosaccharomyces pombe are regulated by

192 t has developmental emphysema with decreased septation in terminal alveoli.

193 ed conidiation was concomitant with restored septation in the absence of the MOBA protein.

194 Heart development before septation in the chick embryo was studied under two hype

195 ta attenuates apoptosis and rescues alveolar septation in vivo.

196 ivation on both anaphase B SPBs and promotes septation, indicating that Fin1 restrains SIN activity o

197 monary outflow tract valvulogenesis, cardiac septation, inflow tract morphogenesis, as well as abnorm

198 The septation initiation network (SIN) and mitotic exit netw

199 a Hippo-related signaling pathway termed the septation initiation network (SIN) controls CR formation

200 ase complex is an important component of the septation initiation network (SIN) in the fission yeast

201 Strikingly, the Hippo-like septation initiation network (SIN) induces Cdr2 dissocia

202 The Schizosaccharomyces pombe septation initiation network (SIN) is an Spg1-GTPase-med

203 fission yeast Schizosaccharomyces pombe the septation initiation network (SIN) is required for stabi

204 ermed the mitotic exit network (MEN) and the septation initiation network (SIN) keeps Cdc14 and Clp1,

205 The septation initiation network (SIN) regulates the timing

206 The septation initiation network (SIN) serves to coordinate

207 The Schizosaccharomyces pombe septation initiation network (SIN) triggers actomyosin r

208 be, a late mitotic kinase pathway called the septation initiation network (SIN) triggers cytokinesis.

209 , Dma1, delays cytokinesis by inhibiting the septation initiation network (SIN) when chromosomes are

210 ents are coordinated with cytokinesis by the septation initiation network (SIN), an essential spindle

211 depends on Sid4 and Cdc11, components of the septation initiation network (SIN), but not on other SIN

212 The kinase cascade of the septation initiation network (SIN), first revealed in fi

213 . cerevisiae and its homologous network, the septation initiation network (SIN), in S. pombe act thro

214 s, cytokinesis/septation is triggered by the septation initiation network (SIN), which first appears

215 (SPB) through a regulatory pathway named the septation initiation network (SIN).

216 rogression through anaphase, interferes with septation initiation network signaling, and additionally

217 dispersing into the cytoplasm, dependent on septation initiation network signaling.

218 he AnBud3-Rho4 module acts downstream of the septation initiation network to mediate recruitment of t

219 trations of Sid2p and Mob1p (proteins of the septation initiation network) and measured their binding

220 p and Mob1p, a protein kinase complex of the septation initiation network, and confirm known interact

221 -cycle regulators such as polo kinase or the septation initiation network.

222 contractile-ring maintenance and affects the septation initiation network.

223 cytokinesis and may negatively regulate the septation initiation network.

224 For example, the Schizosaccharomyces pombe septation-initiation network (SIN), which is responsible

225 erceptible) wall and/or thick (> or =0.5 mm) septations, intracystic or mixed cystic and solid masses

226 Accordingly, defective OFT septation is a life-threatening condition that can occur

227 Overproduction of ZipA at levels that block septation is accompanied by the displacement of FtsZ and

228 Cardiac outflow tract (OFT) septation is crucial to the formation of the aortic and

229 ly circumscribed ribbon around midcell where septation is destined to take place.

230 Thus ventricular septation is established by a steep and correctly positi

231 Upon IcsA localization to these sites, septation is inhibited, suggesting that IcsA recognition

232 -EGFP knock-in mice, showed that ventricular septation is initiated at embryonic day 9 by the movemen

233 nism by which these proteins orchestrate OFT septation is not yet understood.

234 Although the importance of the DMP to AV septation is now established, the molecular and cellular

235 ous fungus Aspergillus nidulans, cytokinesis/septation is triggered by the septation initiation netwo

236 initiating actomyosin ring constriction and septation, is assembled at the SPB through its two scaff

237 iously unrecognized relationship between the septation machinery and ostensibly minor peptidoglycan-m

238 Epithelial remodelling during septation may cause loss of cell-cell or cell-matrix int

239 ha1LG3-5 completely rescued defects in digit septation, neural tube closure, placental labyrinth morp

240 as complicated cysts and one cyst with thin septations, none proved malignant, nor did any of 16 les

241 pite the requirement for NamA for the normal septation of exponentially growing L. monocytogenes cell

242 eart development, consisting of the improper septation of the cardiac outflow tract (OFT) and remodel

243 ent truncus arteriosus (PTA) is a failure of septation of the cardiac outflow tract (OFT) into the pu

244 indbrain rhombomeres 6-8) contributes to the septation of the cardiac outflow tract and the formation

245 Septation of the cloaca is a unique mammalian adaptation

246 h and patterning of the genital tubercle and septation of the cloaca, and a later external genital ph

247 er from respiratory outgrowth or progressive septation of the foregut tube.

248 Septation of the gas-exchange saccules of the morphologi

249 remodelling of the pharyngeal arches and the septation of the heart and outflow tract.

250 Defects in cardiac valve morphogenesis and septation of the heart chambers constitute some of the m

251 irds, mammals and crocodilians into complete septation of the heart into left and right sides, allowi

252 yme as required for valvular development and septation of the heart.

253 unconventional, multi-point and synchronous septation of the intracellular Bdellovibrio, accommodati

254 Septation of the mammalian heart into four chambers requ

255 ein and male lethality because of incomplete septation of the outflow tract of the heart, which produ

256 is involving their migration to the heart or septation of the outflow tract.

257 evelopment of the atrioventricular canal and septation of the outflow tract.

258 les, formation of the urethral tube involves septation of the urethral plate by continued growth of t

259 e proper alignment of the outflow tracts and septation of the ventricles are a highly significant cau

260 l heart defects involve anomalies in cardiac septation or valve development, and understanding the de

261 not associated with presence of radiographic septations or preoperative cyst fluid analysis (carcinoe

262 ation of SIN components is not essential for septation per se, but critical for septation to take pla

263 T or US was diagnostic in 95%, with internal septations present in the hepatic cysts.

264 with an important role in interacting with a septation protein subassembly.

265 ol protein 48 (Cdc48), whereas the bacterial septation proteins FtsZ and minD are lacking in Crenarch

266 Osr1 and Pcsk6 interaction in SHF for atrial septation, providing a molecular framework for understan

267 afish prototypical heart lacks outflow tract septation, raising the question of whether cardiac neura

268 the transcriptional program driving cardiac septation regulates physiologic ventricle partitioning,

269 The process of septation requires precise temporal and spatial organiza

270 M4 in the mycobacterial host led to hindered septation resembling a WhiB2 knockout phenotype whereas

271 endoderm is required for inflow and outflow septation, respectively.

272 al arch arteries and defective outflow tract septation resulting in the formation of a common arteria

273 ial pole malalignment and failure of outflow septation, resulting in a common trunk overriding the ri

274 oss-of-function phenotypes include excessive septation, septal pore degeneration, and uncontrolled Wo

275 masses with thick indistinct walls or thick septations, seven proved malignant.

276 After outflow tract septation should occur, embryos treated with cyclopamine

277 FP-NUDA localized to the hyphal apex and the septation site in DeltanudG cells as in control cells.

278 NAD, SIDB/MOBA successfully localized to the septation site, indicating that their earlier localizati

279 hich is required for actin ring formation at septation sites and also plays a role in polarized morph

280 tsL, and FtsQ are correctly localized to new septation sites in BC202.

281 sion proteins, FtsA and FtsN, from potential septation sites to clusters that colocalize with ZipA ne

282 flow tract formation, atrial and ventricular septation, skeletal development, and palatogenesis.

283 rtion does not depend on the presence of the septation-specific protein PBP3 and is therefore known a

284 Following polar septation, SpoIIE establishes compartment-specific gene

285 on growth, colony morphology, cell division/septation, surface protein/virulence factor expression,

286 s were analyzed before aorticopulmonary (AP) septation through adult stages.

287 in filamentous cells, suggesting QueE blocks septation through interaction with the divisome.

288 nificance of this tissue to atrioventricular septation through study of the previously uncharacterize

289 ntial for septation per se, but critical for septation to take place in a timely manner in A. nidulan

290 hich oscillate from pole to pole and confine septation to the centers of normal rod-shaped cells.

291 ide at the midcell position well before cell septation was conspicuous.

292 Secondary septation was inhibited, so by days 21 to 28 the mean li

293 n Adriamycin-treated embryos, whereas active septation was observed only in normal foregut morphogene

294 ded intracellular bacterial chains for which septation was restored following drug removal.

295 ically modulating chromosome replication and septation, we can systematically tune the penetrance of

296 ases required for myocardial development and septation were reduced in Gata4(+/-);Tbx5(+/-) hearts.

297 -thin smooth walls, and no calcifications or septations were identified by applying a validated natur

298 s produced aerial hyphae with no evidence of septation when grown on a traditional osmotically enhanc

299 enses the rate of DNA synthesis and inhibits septation when the rate of DNA synthesis falls below a c

300 and the lesion was poorly circumscribed with septations, which altogether made it difficult to precis