ライフサイエンスコーパス: sequence similarity

1 assification that does not depend on protein sequence similarity.

2 are 70% identical in sequence and share 88% sequence similarity.

3 etween potential orthologous nodes with high sequence similarity.

4 wed 100% 16S rRNA, rpoB, sodA, and recN gene sequence similarity.

5 e evolutionary origin, despite their lack of sequence similarity.

6 der without modifying genomic loci with high sequence similarity.

7 ryotic subfamilies based on their amino-acid sequence similarity.

8 families based on their cysteine motifs and sequence similarity.

9 family proteins despite lacking identifiable sequence similarity.

10 ta(24-34) WT and hIAPP(19-29) S20G, with 64% sequence similarity.

11 is an effective and accurate measure of DNA sequence similarity.

12 e functional trends mapped to the context of sequence similarity.

13 ly diverged from one another and lack strong sequence similarity.

14 s bacteriophage HK97 MCP despite the lack of sequence similarity.

15 ar molecular interactions, but have moderate sequence similarity.

16 gen of murine polyomavirus despite almost no sequence similarity.

17 aterial packaged and the lack of significant sequence similarity.

18 be grouped into one of six clusters based on sequence similarity.

19 were clustered within networks generated by sequence similarity.

20 domains not correlated with the recombining sequence similarity.

21 inoderms that is searchable via keywords and sequence similarity.

22 betaherpesviruses, despite a lack of obvious sequence similarity.

23 des with highest transport capacities shared sequence similarities.

24 immediately evident from the overall fold or sequence similarities.

25 e Fab-7 LBC recognition elements display few sequence similarities.

26 red to as MOSC1 and MOSC2), which share high sequence similarities.

27 g interacting protein (HHIP) and family with sequence similarity 13 member A (FAM13A) were shown to h

28 ed factors, FAM150A and FAM150B (family with sequence similarity 150 member A and member B), stimulat

29 rticular disease and in FAM155A (family with sequence similarity 155A; rs67153654-A: P=3.0 x 10(-11),

30 The family with sequence similarity 20 (Fam20) kinases phosphorylate ext

31 onditionally inactivated FAM20B (Family with sequence similarity 20 member-B), which is a newly ident

32 at the atypical secretory kinase family with sequence similarity 20, member B (Fam20B) phosphorylates

33 The family with sequence similarity 20, member C (Fam20C) has recently b

34 e with universal inactivation of Family with sequence similarity 20-C (FAM20C) were associated with t

35 Here, we demonstrate that family with sequence similarity 20C (Fam20C), a recently characteriz

36 One member, family with sequence similarity 20C (Fam20C), is the physiological G

37 gh reporter and ChIP assays that family with sequence similarity 213, member A (FAM213A), a peroxired

38 y unidentified prokaryote homologs with high sequence similarity (24-32%) to eukaryote HCN and CNG ch

39 esult: rs2629540 at the FAM53B ('family with sequence similarity 53, member B') locus.

40 Previously, we identified family with sequence similarity 65, member B (Fam65b), as a protein

41 The human FAM86A (family with sequence similarity 86) protein belongs to a recently id

42 Here, we identified family with sequence similarity 92, member A (FAM92A) and FAM92B, wh

43 ed structural motifs and show relatively low sequence similarity across different species, which make

44 Using sequence similarity alone, SSpro's accuracy is between 7

45 oduce a sharp distinction between the use of sequence similarity alone, typically in the form of sequ

46 will yield better orthology predictions than sequence similarity alone.

47 ving on the order of >/= 85% accuracy, using sequence similarity alone.

48 ion (BMCSI), which first measures HA protein sequence similarities among influenza viruses (especiall

49 ulum (ER)-anchoring membrane domain with low sequence similarity among eukaryotic kingdoms and a cons

50 However, due to sequence similarity among genes and among isoforms, the

51 ppear to have driven a near complete loss of sequence similarity among modern tetherin genes and thei

52 Here we find that, despite the high sequence similarity among the three ApoE variants, only

53 These analyses showed high levels of sequence similarity among Tp0750 orthologs from pathogen

54 Sequence similarity analysis shows a total of 3,220 uniq

55 domain structures based on structure and/or sequence similarities and plays important roles in the s

56 atrices such as Blosum62 are used to measure sequence similarities and to identify distant homologues

57 AcMADS1 shares 67 % protein sequence similarity and a similar expression pattern in

58 3) and olive (Ole e 3, Ole e 8) showed high sequence similarity and cross-reacted with allergic pati

59 ad a common Zn(2+) bimetallo core but little sequence similarity and different auxiliary domains.

60 seven main families (ABCA to ABCG) based on sequence similarity and domain organizations.

61 Sequence similarity and expression only partly predicted

62 We utilized sequence similarity and gene expression to categorize th

63 s to overcome several obstacles such as high sequence similarity and genetic recombinations between C

64 mbined approach that takes into account both sequence similarity and genome context.

65 Despite high protein sequence similarity and partially overlapping activity p

66 VDAC has three isoforms with >70% sequence similarity and redundant roles in metabolite an

67 therin genes in various organisms exhibit no sequence similarity and share only a common architecture

68 double-stranded RNA (dsRNA) receptor, shares sequence similarity and signaling pathways with RIG-I ye

69 adrenergic receptors (alpha2-ARs) based upon sequence similarity and the ability to interact with nor

70 nhibitor 1 (SPI-1) from Arabidopsis thaliana Sequence similarity and the shared beta-alpha-beta-beta-

71 These node matches are based on sequence similarity and/or interaction patterns.

72 ly reflect evolutionary distance measured by sequence similarity); and Variant groups (which largely

73 clustered into families based on amino acid sequence similarities, and belonging to a particular fam

74 enera differentiated by genome organization, sequence similarity, and insect vector.

75 e into disjoint transcript clusters based on sequence similarity, and introduces the notion of sig-me

76 the O9a prototype, but they share only weak sequence similarity, and the putative binding pocket for

77 limitations of methods that rely solely upon sequence similarity are attracting increased attention.

78 Placement of a sequence similarity based model of the HAMP1-5 protein i

79 ing patterns of all aligned PPI networks and sequence similarities between their proteins.

80 rms in polyploid species because of the high sequence similarity between coexisting subgenomes.

81 Further, sequence similarity between distant wild populations sug

82 fs-genes was grouped into clusters based on sequence similarity between fs-proteins (conceptually tr

83 allenge in studying the IGHV locus: the high sequence similarity between gene segments in different g

84 2 731 fs-genes into 19 430 clusters based on sequence similarity between protein products (fs-protein

85 Our method calculates true sequence similarity between query sequences and database

86 However, massive volume of dataset, high sequence similarity between related species, skewed micr

87 lineage, there exists a significant level of sequence similarity between the ATPase genes carried by

88 Extensive hyperpolymorphism and sequence similarity between the HLA genes, however, pose

89 Similar findings in humans and the sequence similarity between the human and baboon viruses

90 disease remains elusive, in part because low sequence similarity between the human and rodent H4 rece

91 tween species is governed in part by primary sequence similarity between the infectious prion aggrega

92 a has historically been difficult due to the sequence similarity between the polymorphic alleles.

93 Despite high sequence similarity between the RRs BceR and PsdR and th

94 dicative of gene duplication despite lack of sequence similarity between the two halves.

95 ion response RNA, despite a complete lack of sequence similarity between the two RNAs.

96 Taking advantage of the high sequence similarity between the two transporters, we com

97 imilar to that of sbmA in spite of a lack of sequence similarity between these DNA elements.

98 emains challenging due to the high degree of sequence similarity between these isoforms (98.9%).

99 Here, we report the sequence similarity between this peptide and a conserved

100 Our method corrects for 3' UTR background sequence similarity between transcripts, which is known

101 Given the high degree of sequence similarity between vertebrate alpha-syns, we in

102 ype of protein domain that is not defined by sequence similarity but by the presence of multiple S/TQ

103 receptor (iGluR) superfamily on the basis of sequence similarity, but do not bind l-glutamate.

104 We demonstrate that traditionally defined sequence similarity can be very low for pairs of sequenc

105 xamples, we also show how DNA-binding domain sequence similarity can yield confounding results as an

106 esiding on different chromosomes and lacking sequence similarity, cCNV between these loci is strong,

107 ously named folate receptor (FR) 4, based on sequence similarity considerations - triggers membrane a

108 y-pathway basis; codon usage, abundance, and sequence similarity contributed predictive power.

109 zymatic activities of LpxE and EptA based on sequence similarity could be successfully validated by m

110 omic data, e.g. sensitivity to the choice of sequence similarity cutoff used to define operational ta

111 Despite the high degree of sequence similarity, CYP1A1 was found to localize to dis

112 Networks that were reconciled with sequence similarity data and strongly enforced reversibi

113 The data imply that, despite their high sequence similarity, differential phosphorylation of Lhc

114 In conclusion, sequence similarity does not necessarily result in struc

115 Our data show that sequence similarity does not translate to structural mim

116 Surprisingly, although little sequence similarity exists to known insecticidal protein

117 Mutations in the Family with sequence similarity (FAM) 20 gene family are associated

118 esins, and although lacking a high degree of sequence similarity, family members do share common pred

119 ify highly periodic repeats with significant sequence similarity, for which evolutionary rates and se

120 The TRPML proteins share high sequence similarities, form hetero-tetramers, and serve

121 omologous family that, despite indiscernible sequence similarity, form a distinct branch of the Gcn5-

122 /5/10, AGO2/3/7 and AGO4/6/9, based on their sequence similarity, functional redundancy, as well as s

123 Unexpectedly, high-sequence similarity grouped some outbreak and archival i

124 Detection of protein homology via sequence similarity has important applications in biolog

125 We found that well-accepted methods based on sequence similarity (i.e., BLAST) have a dominant effect

126 s of ribosomal proteins (RPs) that show high sequence similarity/identity.

127 e demonstrate that after accounting for kmer sequence similarities in 3' UTRs, a statistical linear m

128 were discovered among the genes that have no sequence similarities in other organisms.

129 Essentially we use 3' UTR sequence similarity in place of population cryptic relat

130 erestingly, plant and animal TPCs share high sequence similarity in the filter region, yet exhibit dr

131 Homologs of IruO were identified by sequence similarity in the genomes of Gram-positive bact

132 ately affected by APA, primarily due to high sequence similarity in the motifs utilized by polyadenyl

133 istics, seven groups can be distinguished by sequence similarity, indicating structural and functiona

134 Using only the sequence similarity information, MS-kNN had term-based A

135 Gotcha and BLAST, which were based solely on sequence similarity information.

136 However, problems arise when sequence similarity is low.

137 gnment of short motifs, even if their mutual sequence similarity is only partial.

138 toformans NBRC 15712(T) (96.3% 16S rRNA gene sequence similarity) is the closest Bacillus species acc

139 Because of sequence similarities, it is particularly difficult to g

140 nine methyltranserase termed BlArsM with low sequence similarities (</= 39%) to other ArsMs.

141 nucleotide k-mer frequency as the proxy for sequence similarity measurement.

142 Recent studies have identified family with sequence similarity member 20C (FAM20C) as a kinase that

143 Family with sequence similarity member 20C is the primary but not th

144 By using HMM-HMM alignment as the sequence similarity metric, CMsearch clearly outperforms

145 across the entire superfamily and computed a sequence similarity network to guide classification into

146 Sequence similarity networks and genome neighborhood net

147 Using sequence similarity networks and genome neighborhood net

148 Using the resulting sequence similarity networks, we chose targets that broa

149 domain architecture of the enzymes and using sequence similarity networks, we examined the links betw

150 iles of functional and other attributes, and sequence similarity networks.

151 ved public sequences were central within TCR sequence-similarity networks.

152 The synergistic use of sequence similarity networks3 and GNNs will facilitate t

153 Despite their high sequence similarity, NiV and HeV exhibit apparent differ

154 Genetic sequence similarities of 99%-100% among IAVs of 1 market

155 In silico analysis reveals sequence similarities of GDAP1 to glutathione S-transfer

156 its wild type and a nonlinear dependence on sequence similarity of neoantigens to known antigens.

157 ce of NAHR, whereas chromosomal position and sequence similarity of paired SDs are also involved in N

158 Due to the sequence similarity of several genes on the megaplasmid,

159 Because of high sequence similarity of some of the 12 GM targets, two se

160 However, the level of sequence similarity of TCR repertoires within and betwee

161 sterior probability based upon the degree of sequence similarity of the database hit to the query seq

162 This cross-reactivity is explained by the sequence similarity of the two viruses, as the ZIKV pept

163 Given the high sequence similarity of these paired viral epitopes (56 a

164 have inferred orthology based either on pure sequence similarity or using gene-tree approaches.

165 ysteines forming four disulfide bridges with sequence similarities resembling the alpha-potassium cha

166 wn that this matrix can be optimized so that sequence similarity scores correlate well with structure

167 ent of many protein analysis systems such as sequence similarity search, sequence alignment, and phyl

168 mited by the intrinsic limitations of common sequence similarity searches and available databases.

169 Comprehensive sequence similarity searches in the genome of the parasi

170 BLAST provides sequence similarity searches of GenBank and other sequen

171 BLAST provides sequence similarity searches of GenBank and other sequen

172 BLAST provides sequence similarity searches of GenBank and other sequen

173 BLAST provides sequence similarity searches of GenBank and other sequen

174 BLAST provides sequence similarity searches of GenBank and other sequen

175 ng, de novo assembly, and translated protein sequence similarity searches, numerous known and previou

176 Using sequence similarity searches, we have identified 257 new

177 that might account for systematic errors in sequence similarity searches.

178 ssitate quality control, genome assembly and sequence similarity searching before an isolate's ST can

179 utionary information captured in the form of sequence similarity, sequence profiles and residue conse

180 Sequence similarity studies of Camelina with the other r

181 Sequence similarities suggest the presence of a related

182 ngly, these Zap proteins show no discernable sequence similarity, suggesting that they likely harbor

183 -2/4-binding activity, an assertion based on sequence similarity that TSP-1 shares with the von Wille

184 revisiae and Escherichia coli HADs share low sequence similarities, the comparison of their substrate

185 Despite sequence similarity, the coding potentials of UPOV and A

186 Despite sharing high sequence similarity, the two enzymes have different subs

187 While the stems of SL1 and SLC share little sequence similarity, their end loops are of the same siz

188 Short reads require a high level of sequence similarities to annotated genes to confidently

189 the complete and partial genomes showing no sequence similarities to public databases.

190 demonstrate its remarkable architectural and sequence similarities to spider silk fibroins, indicatin

191 chment shared 98.6%, and 98.5% 16S rRNA gene sequence similarities to Sulfurospirillum multivorans.

192 der of use during VLRC assembly by virtue of sequence similarities to the incomplete germ-line gene a

193 s molecules involved in such death show some sequence similarities to those involved in apoptosis, le

194 novo, and contigs with predicted amino acid sequence similarities to viruses in the nonredundant pro

195 nscripts, 50 of which had a greater than 99% sequence similarity to 48 of the SSTs.

196 unique tandem repeat domain that shares high sequence similarity to a non-syntenic zebrafish analog,

197 ecific transcription was identified based on sequence similarity to a previously characterized bindin

198 ify SLC38A9, an uncharacterized protein with sequence similarity to amino acid transporters, as a lys

199 activity, whereas the C-terminal domain has sequence similarity to an FMN-dependent family of nitror

200 all gap-filling reactions were supported by sequence similarity to annotated enzymes, four draft net

201 he structures of proteins without detectable sequence similarity to any protein of known structure re

202 These non-syntenic genes on 3B have high sequence similarity to at least one other gene in the wh

203 Because of its sequence similarity to Bax and Bak, Bok has long been co

204 transporters as templates but these have low sequence similarity to CFTR and are not ion channels.

205 ical endo-beta-1,4-xylanase, despite the low sequence similarity to characterized GH10 xylanases.

206 We identified a transcript with high sequence similarity to crustacean cardioactive peptide (

207 protein called Tpr (thiol protease) that has sequence similarity to cysteine peptidases of the papain

208 terminal domain in HgGLAND18 contains unique sequence similarity to domains of an immunosuppressive e

209 ated from Leptospira licerasiae-which shares sequence similarity to eukaryotic CNG and HCN channels-i

210 Sequence similarity to genes characterized in previous s

211 ate genes for these traits in pigeonpea have sequence similarity to genes functionally characterized

212 st Tsr1 is a ribosome biogenesis factor with sequence similarity to GTPases, which is essential for c

213 d to be a 40-amino acid peptide showing high sequence similarity to human (93%), mouse (93%), and Xen

214 atics analysis of MIP showed some amino acid sequence similarity to human FK506-binding proteins (FKB

215 This exon has sequence similarity to I-connectin/Titin and was acquire

216 ed aquifer sediments, a phylotype with 92.7% sequence similarity to Ignavibacterium album was identif

217 transformation at DNA sites with increasing sequence similarity to its target.

218 Despite very low sequence similarity to known homologues, TraB (VirB10 ho

219 unresolved because both Izumo1 and Juno lack sequence similarity to known membrane fusogens.

220 one of our nanostructures showed significant sequence similarity to known pH-sensitive motifs, sugges

221 new candidates for bacteriocins that bear no sequence similarity to known toxins.

222 105 members and exhibits only a very limited sequence similarity to known unsaturated beta-glucuronyl

223 utative viral sequences that lack detectable sequence similarity to known viruses.

224 e-art statistical method to quantify a CRM's sequence similarity to many different training sets of C

225 FriEPRV shows sequence similarity to members of the Caulimoviridae par

226 es (e.g., coelacanths) does tetherin exhibit sequence similarity to one potential sister gene.

227 ed enzyme at a location predicted by primary sequence similarity to only the selected C-extein sequen

228 ational taxonomic units showed the strongest sequence similarity to Ophiocordyceps, Verticillium, Pse

229 lacking NPR-17, which encodes a protein with sequence similarity to opioid receptors.

230 ycoside hydrolase family 1 and has up to 76% sequence similarity to other beta-glucosidases.

231 The 9,174-nt-long genome showed limited sequence similarity to other known viruses.

232 of 889 bp, over 90% of which has significant sequence similarity to other legumes.

233 tertiary structural information and primary sequence similarity to other proteins.

234 fied peptides cluster products, reporting of sequence similarity to proteins encoded in experimentall

235 r role of CelTOS is unknown because it lacks sequence similarity to proteins of known function.

236 lthough WFBV shows low to moderate levels of sequence similarity to Quaranfil virus and Johnston Atol

237 Some identified species had low sequence similarity to reported species indicating the p

238 by ORF CT009 interacts with MreB despite low sequence similarity to RodZ.

239 o other U.S. PDCoV strains, with the highest sequence similarity to South Korean strain KNU14-04.

240 ein-coupled apelin receptor, despite lack of sequence similarity to the established ligand apelin.

241 Because Merlin has high level of sequence similarity to the Ezrin-Radixin-Moesin family o

242 HupK, a scaffolding protein with a moderate sequence similarity to the hydrogenase large subunit and

243 0), that harbors a C-terminal extension with sequence similarity to the nitrite/sulfite reductase fam

244 s of viral proteins that have no and distant sequence similarity to the ones used for training, recep

245 disordered central segment of MDMX that has sequence similarity to the p53 transactivation domain.

246 nd in almost all eubacteria and plants, with sequence similarity to the RecA strand exchange protein

247 peptide, delta-conotoxin TsVIA, has striking sequence similarity to these delta-conotoxins from pisci

248 s of the 'variable side' with structural and sequence similarity to those encoding survival traits on

249 Its TPR domain has sequence similarity to TPR domains of transcriptional re

250 Arabidopsis (Arabidopsis thaliana) that has sequence similarity to yeast ICP55.

251 These proteins show sequence similarity to yeast prion proteins, which can i

252 lusive to the Y in all species examined, yet sequence similarity to YG2 is not detectable in the geno

253 Since the TM-domain template had low sequence-similarity to the TM domains of the CNG channel

254 clustered group of receptors that share core sequence similarities, together with a dispersed set of

255 istance, these proteins share structural and sequence similarities, underscoring their importance acr

256 zes the conflicting goals of topological and sequence similarity using the concept of Pareto dominanc

257 Sequence similarity was a poor indicator of ability: Sev

258 om the Model SEED database for which minimal sequence similarity was found in their genomes.

259 ifficulty making use of both topological and sequence similarity when aligning, with either one or th

260 me Annotation Pipeline (PGAP) relies more on sequence similarity when confident comparative data are

261 thologs in different species despite limited sequence similarity, which is applicable to mammalian an

262 edictions as a function of protein/structure sequence similarity, which permits the use of relatively

263 ty, which permits the use of relatively weak sequence similarities with an appropriate confidence mea

264 y, some proteins specific to Lh VLPs possess sequence similarities with bacterial secretion system pr

265 t gamma-clade HD-Zip I TFs share significant sequence similarities with homologous genes from other p

266 Sequence similarities with tropomyosin and myosin from m

267 STIV shares structural, morphological, and sequence similarities with viruses from other domains of

268 AD family, AAD3 shares the highest degree of sequence similarity with AAD2 and AAD4.

269 d polypeptide (IAPP), a peptide which shares sequence similarity with Abeta.

270 A49 does not share overall sequence similarity with any protein of known structure

271 d on cassava whole-genome sequence and their sequence similarity with Arabidopsis TCPs.

272 putatively secreted proteins shared highest sequence similarity with archaeal and fungal enzymes, wh

273 ructurally, beta-hCG shares a high degree of sequence similarity with beta-hLH, including a common N-

274 to Bacteria, of which 12% shared the highest sequence similarity with candidate phyla (10,11) .

275 predicted transmembrane domains, patches of sequence similarity with cellular G-protein-coupled rece

276 both twins and their siblings had more vocal sequence similarity with each other than with non-siblin

277 Many of these effectors share structural and sequence similarity with eukaryotic proteins.

278 Although FLNb shows high amino acid sequence similarity with FLNa, we reveal that only FLNa,

279 are small reductases with a high amino acid sequence similarity with glutaredoxins and mycoredoxins

280 otic methyltransferase (Ma Mtase), which has sequence similarity with ICMT in its AdoMet binding site

281 Although there was little sequence similarity with KSHV microRNAs, one candidate c

282 s enzyme, reannotated as LpxJ due to limited sequence similarity with LpxM, catalyses addition of a C

283 s BAFF-like gene in lampreys exhibits higher sequence similarity with mammalian BAFF than APRIL.

284 II RubisCOs were recovered which share high sequence similarity with metagenomic scaffolds from uncu

285 cult due to its high structural homology and sequence similarity with off-target hCAs.

286 consists of 1,359 amino acids, sharing high sequence similarity with Orf29/30 of E. tarda strain EIB

287 BCL-3 that interacts with p50 and shares low sequence similarity with other IkappaB proteins.

288 in cardiac muscle with high catalytic domain sequence similarity with other MLCKs but lacking an auto

289 virus isolated from April to May shared high sequence similarity with other strains from eastern Chin

290 MnxG shares sequence similarity with other, structurally characteriz

291 r of the p53 family, shares a high degree of sequence similarity with p53.

292 sults indicate that, although SynDIG4 shares sequence similarity with SynDIG1, it might act through a

293 nispryn, encoded by Fsd2, that has extensive sequence similarity with the C-terminus of myospryn.

294 erestingly, an internal region of Mcc shares sequence similarity with the central domain of the prion

295 ized chimera of a snail AChBP, which has 71% sequence similarity with the extracellular ligand-bindin

296 The emergent H5N6 viruses, which share high sequence similarity with the human isolate A/Guangzhou/3

297 re significantly shorter and share almost no sequence similarity with the S. cerevisiae homolog.

298 N pathway, but surprisingly, they exhibit no sequence similarity with their RSV equivalents.

299 ase A paralogs, but the toxin does not share sequence similarity with these nucleases and lacks the c

300 RIFMO shares moderate sequence similarity with well characterized flavoprotein