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1 otide-binding site, leucine-rich repeat, and serine threonine protein kinase.
2 ified as casein kinase II (CKII), a cellular serine-threonine protein kinase.
3 that it encodes a cytoplasmically localized serine-threonine protein kinase.
4 ubiquitously expressed and highly conserved serine/threonine protein kinase.
5 2alpha (casein kinase II), a multifunctional serine/threonine protein kinase.
6 , Ku) for its activation as a robust nuclear serine/threonine protein kinase.
7 otrimeric DNA-PK complex is then active as a serine/threonine protein kinase.
8 a protein complex and is a target of the Hpo serine/threonine protein kinase.
9 PAS kinase is an evolutionarily conserved serine/threonine protein kinase.
10 ectors such as p21-activated kinase (PAK), a serine/threonine protein kinase.
11 tely 465 kDa catalytic subunit [DNA-PKcs], a serine/threonine protein kinase.
12 ccharomyces cerevisiae KIN1, which encodes a serine/threonine protein kinase.
13 (DAP) kinase, a calcium/calmodulin-dependent serine/threonine protein kinase.
14 ntrols, in the ciliary gene NEK2, encoding a serine/threonine-protein kinase.
15 ase1 (LIMK1) is a member of a novel class of serine-threonine protein kinases.
16 road-spectrum inhibitor of both tyrosine and serine/threonine protein kinases.
17 or tyrosine kinases, Src family members, and serine/threonine protein kinases.
18 in, which possessed domains of homology with serine/threonine protein kinases.
19 ber of the PCTAIRE subfamily of cdc2-related serine/threonine protein kinases.
20 s, DNA-binding transcription regulators, and serine/threonine protein kinases.
21 activity levels of a large number (>100) of serine/threonine protein kinases.
23 ound that knocking down receptor-interacting serine/threonine protein kinase 1 (Ripk1) increased both
25 f PTPN12 by CDK2 impaired recruitment of the serine/threonine-protein kinase 1 (PAK1) to HER2, result
28 daptor proteins such as receptor-interacting serine/threonine-protein kinase 1 (RIPK1), receptor-inte
29 and risk for cancer associated with germline serine/threonine protein kinase 11 (STK11) mutations tha
33 2 (NOD2) and downstream receptor-interacting serine/threonine-protein kinase 2 (RIPK2) by human cytom
34 ed NOD2, the downstream receptor-interacting serine/threonine-protein kinase 2 (RIPK2), resulting in
36 ircadian clock and the cell cycle exists via serine/threonine protein kinase-29 (STK-29), the Neurosp
38 ediator of necroptosis, receptor-interacting serine/threonine-protein kinase 3 (RIP3), and HMGB1.
39 otein kinase 1 (RIPK1), receptor-interacting serine/threonine-protein kinase 3 (RIPK3), TIR-domain-co
40 GATA3, OX40 ligand, and receptor-interacting serine/threonine-protein kinase 4 (RIPK4), were downregu
41 e, we demonstrated that the tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially
44 eticulum (ER) kinase, is an ER transmembrane serine/threonine protein kinase activated during ER stre
45 otein that includes putative motifs for both serine/threonine protein kinase activity and DNA binding
47 of cell proliferation and apoptosis through serine-threonine protein kinase AKT-beta-catenin and Win
54 hat the La protein is a direct target of the serine/threonine protein kinase Akt on threonine 301, an
57 ted kinase) inhibitor U0126, but not by AKT (serine/threonine protein kinase Akt) and PI3K (phosphati
60 due to the inhibition of phosphorylation of serine/threonine protein kinase (AKT) and its downstream
63 utually exclusive amplification of RAC-alpha serine/threonine-protein kinase (AKT1) or AKT2 and other
64 cells in vitro and in vivo by inhibiting AKT serine/threonine-protein-kinase (AKT3), ribosomal-protei
65 dicated that ubiquinone pathway and the MAPK serine-threonine protein kinase and collagens gene-famil
66 th Warts (Wts)/large tumor suppressor (Lats) serine/threonine protein kinase and ability to upregulat
68 two Z-disc kinases (striated muscle-specific serine/threonine protein kinase and obscurin) was dramat
69 t of varicella-zoster virus (VZV) ORF47 is a serine/threonine protein kinase and tegument component.
70 to inhibit the mammalian target of rapamycin serine/threonine protein kinase and therefore T cell cyc
72 lts bring to light FadD32 phosphorylation by serine/threonine protein kinases and its correlation wit
73 cific phosphodiesterases, histidine kinases, serine/threonine protein kinases and protein phosphatase
74 that the native protein is phosphorylated by serine/threonine protein kinases and that this phosphory
75 ns used to infect C. elegans such as Kin1 (a serine/threonine protein kinase) and Rom2 (a Rho1 guanyl
78 e hybrid histidine protein kinase, EspA, two serine/threonine protein kinases, and a putative transpo
79 polymerase subunit 7; IIV3-044L, a putative serine/threonine protein kinase; and IIV3-080R, a protei
80 ple members of the casein kinase I family of serine/threonine protein kinases are involved in positiv
81 a show that ELM1, and genes encoding related serine/threonine protein kinases, are required for regul
82 ins contain a penicillin-binding protein and serine/threonine protein kinase-associated (PASTA) domai
83 ve disease caused by loss of function of the serine/threonine protein kinase ATM (ataxia telangiectas
88 f somatic mutations in the gene encoding the serine-threonine protein kinase B-RAF (BRAF) in the majo
92 he phosphoinositide 3-kinase (PI3K) and Akt (serine/threonine protein kinase B) survival pathway in r
93 calcium/calmodulin-dependent kinase kinase, serine/threonine protein kinase B, protein kinase A, ext
94 anisms by which some melanoma cells adapt to Serine/threonine-protein kinase B-Raf (BRAF) inhibitor t
95 velopment of a novel method for the assay of serine/threonine protein kinases based on fluorescence l
97 arbouring point mutations (Val600Glu) in the serine/threonine-protein kinase BRAF (BRAF(V600E)) depen
101 dependent manner, through diabetes-activated serine/threonine protein kinase C beta2 (PKCbeta2)-depen
102 c domain of CD86 was truncated or mutated at serine/threonine protein kinase C phosphorylation sites,
103 the delta isoform of phospholipid-dependent serine/threonine protein kinase C, which then accelerate
104 -SnRK superfamily consists of seven types of serine-threonine protein kinases: calcium-dependent prot
106 regulation of peripheral B-cell survival by serine/threonine protein kinase Cdelta (PKCdelta): spont
107 ue of Cell, report that the C2 domain of the serine/threonine protein kinase Cdelta is a phosphotyros
108 nd specifically inhibit the master regulator serine/threonine protein kinase CK2 and the wild-type/mu
110 Kinase2 (CK2) is an evolutionarily conserved serine/threonine protein kinase composed of two catalyti
111 pendent protein kinase (DNA-PK) complex is a serine/threonine protein kinase comprised of a 469-kDa c
113 in-dependent protein kinase II (CaMKII) is a serine/threonine protein kinase critically involved in s
114 ctivates a signal relay pathway in which the serine/threonine protein kinase D (PKD) activates the NF
115 physiological function of a newly described serine/threonine protein kinase D2 (PKD2) in aspects of
116 uires activities of tyrosine kinase TYK2 and serine/threonine protein kinase D2 (PKD2), whose recruit
117 hosphorylation is carried out by the nuclear serine/threonine protein kinase DNA-PKcs and promoted by
119 phototropins, to activation of a C-terminal serine/threonine protein kinase domain, which is tightly
122 everal functions have been attributed to the serine/threonine protein kinase encoded by open reading
126 ted kinase (ERK) is a prototypic member of a serine/threonine protein kinase family known as mitogen-
127 iogenesis, members of the conserved atypical serine/threonine protein kinase family, the RIO kinases
129 Previous studies have implicated a family of serine/threonine protein kinases found in rhoptries (ROP
130 nship between two components of the HSC, the serine/threonine protein kinase Fused (Fu) and the kines
131 Kinesin-related protein Costal2 (Cos2), the serine/threonine protein kinase Fused (Fu), and the tran
134 UL13, UL44, and US6 genes encoding the UL13 serine/threonine protein kinase, glycoprotein C (gC), an
135 utations in the Drosophila gene encoding the serine-threonine protein kinase Greatwall have previousl
136 Protein kinase D (PKD), a newly described serine/threonine protein kinase, has been implicated in
139 t, or protein kinase B, is a multifunctional serine-threonine protein kinase implicated in a diverse
140 eracted with integrin-linked kinase (ILK), a serine/threonine protein kinase implicated in cancer cel
141 ypical protein kinase C (aPKC) are conserved serine/threonine protein kinases implicated in the estab
142 endent kinase II (CaMKII), a multifunctional serine/threonine protein kinase in neurons, is believed
144 32)P]ATP in the presence of staurosporine (a serine/threonine protein kinase inhibitor), genistein (a
145 ated protein kinases (MAPKs) are a family of serine-threonine protein kinases involved in many cellul
146 ase (DAPK) is a calcium calmodulin-regulated serine/threonine protein kinase involved in ischemic neu
147 WNK1 [with no lysine (K)-1] is a 250-kDa serine/threonine protein kinase involved in the maintena
149 for posttranslational regulation of the Akt serine/threonine protein kinase involving ubiquitination
151 PKC) family of Ca(2+) and/or lipid-activated serine-threonine protein kinases is implicated in the pa
154 th related signals, including the actions of serine-threonine protein kinases, is less well defined.
155 Glycogen synthase kinase 3beta (GSK3beta), a serine/threonine protein kinase, is a key target of drug
156 Open Stomata 1 (OST1) (SnRK2.6 or SRK2E), a serine/threonine protein kinase, is a positive regulator
157 thioredoxin-fold-containing eukaryotic-like serine/threonine protein kinase, is a virulence factor i
158 expression of p21-activated kinase (Pak)1, a serine/threonine protein kinase, is activated in mammary
161 ), the Drosophila Ndr (Nuclear Dbf2-related) serine/threonine protein kinase, is required for the nor
162 ), the Drosophila nuclear Dbf2-related (Ndr) serine/threonine protein kinase, is required for the nor
163 silon (PKC epsilon), a member of a family of serine/threonine protein kinases, is a transforming onco
166 estigated the functions of the Hippo pathway serine/threonine-protein kinases Lats1 and Lats2, which
167 protein kinases (PAK)-LIM domain-containing serine/threonine protein kinases (LIMK) signaling pathwa
169 re, we demonstrate an essential role for the serine/threonine protein kinase mammalian target of rapa
170 ough the phosphoinositide-3 kinase-RAC-alpha serine/threonine-protein kinase-mechanistic target of ra
171 ization and the levels of PknA/PknB (PknA/B) serine-threonine protein kinase-mediated Wag31 phosphory
176 , MSMEG_6129 and a predicted eukaryotic like serine/threonine protein kinase, MSMEG_5437, in the intr
178 other proteins known to bind wild-type CCM3, serine/threonine protein kinase MST4 (MST4), sterile 20-
185 lyzed by Pak2, a member of the p21-activated serine/threonine protein kinase (Pak) family and regulat
186 ned the integrity of the CDC42-p21-activated serine/threonine protein kinases (PAK)-LIM domain-contai
187 -type channels are modulated by a variety of serine/threonine protein kinase pathways, which indicate
188 ic linkages, such as signaling domains (e.g. serine/threonine protein kinase), peptidoglycan-processi
189 protein kinases; however, the proto-oncogene serine/threonine protein kinase PIM1 (PIM-1) and glycoge
190 n of each individual complex, stabilizes the serine-threonine protein kinase PINK1 on the mitochondri
192 escence2 (bif2) encodes a co-ortholog of the serine/threonine protein kinase PINOID (PID), which regu
193 pstein-Barr virus (EBV) BGLF4 gene encodes a serine/threonine protein kinase (PK) that is expressed i
194 his study concerns one of these enzymes, the serine/threonine protein kinase PknF, that is encoded in
195 The p21-activated kinase (PAK) family of serine/threonine protein kinases plays important roles i
197 NA (dsRNA)-activated protein kinase (PKR), a serine/threonine protein kinase, plays an important role
198 inase (PAK) 2, a member of the PAK family of serine/threonine protein kinases, plays an important rol
200 eport the efficacy of the Raf proto-oncogene serine/threonine protein kinase (RAF) inhibitor, PLX8394
202 distinct molecular components including the serine/threonine protein kinase receptor-interacting pro
203 esis that p(21)-activated kinase-1 (Pak1), a serine-threonine protein kinase regulated by Ras-related
207 e comparisons between different cdc2-related serine/threonine protein kinases reveal that these prote
208 have emphasized the importance of the active serine-threonine protein kinase rhoptry protein 18 (ROP1
209 amage, and elevation of receptor-interacting serine/threonine-protein kinase (RIP) 1/3 were observed
212 target Rho-associated coiled-coil containing serine/threonine protein kinase (ROCK) is amplified by s
215 al acetaldehyde/ethanol dehydrogenase (Aad), serine/threonine protein kinase, serine/threonine protei
216 ption factor Drosophila FOXO (dFOXO) and the serine/threonine protein kinase shaggy, the fly ortholog
218 type 2C protein phosphatase (PP2C) ABI1, the serine/threonine protein kinase SnRK2.6/OST1 and the tra
221 entified and characterized a eukaryotic-type serine/threonine protein kinase (Stk1) and its cognate p
222 of these scaffolds, potent inhibitors of the serine/threonine-protein kinase STK10 were synthesized.
223 include the sensor/signaling proteins of the serine/threonine protein kinase (STPK) family that have
225 Mycobacterium tuberculosis genome encodes 11 serine/threonine protein kinases (STPKs) that are struct
227 ological inhibition of either IKKbeta or the serine/threonine protein kinase TAK1 in monocytes blocke
229 tein kinase D (PKD) family consists of three serine/threonine protein kinases termed PKD, PKD2, and P
231 irus 1 (HSV-1) US3 gene is a multifunctional serine-threonine protein kinase that can block apoptosis
232 rated by these stimuli converge on mTORC1, a serine-threonine protein kinase that has been termed the
233 protein-coupled receptor kinase-2 (GRK2), a serine-threonine protein kinase that induces internaliza
234 le inhibitor of Polo-like kinase 4 (Plk4), a serine-threonine protein kinase that initiates centriole
235 ogen synthase kinase (GSK)-3 is a ubiquitous serine-threonine protein kinase that participates in a m
236 ubiquitously expressed and highly conserved serine-threonine protein kinase that regulates cellular
238 oil-containing kinases (ROCK1 and ROCK2) are serine-threonine protein kinases that are involved in th
239 vated kinases (Paks) are Cdc42/Rac-activated serine-threonine protein kinases that regulate several k
241 e kinase 3) is a widely expressed, mammalian serine/threonine protein kinase that activates multiple
242 Protein kinase B (PknB) is a transmembrane serine/threonine protein kinase that acts as an essentia
245 an target of rapamycin is a highly conserved serine/threonine protein kinase that controls initiation
247 n kinase Czeta (PKCzeta) is an intracellular serine/threonine protein kinase that has been implicated
252 VZV) open reading frame 66 (ORF66) encodes a serine/threonine protein kinase that is not required for
253 d among the alphaherpesviruses and encodes a serine/threonine protein kinase that is not required for
254 or progression locus 2 (Tpl2) gene encodes a serine/threonine protein kinase that is overexpressed in
256 TGF)-beta-activated kinase 1 (TAK1) is a key serine/threonine protein kinase that mediates signals tr
257 sphoinositide-dependent kinase-1 (PDK1) is a serine/threonine protein kinase that phosphorylates memb
258 -terminal kinase (JNK) is a stress activated serine/threonine protein kinase that phosphorylates nume
259 tegrin-linked kinase (ILK), an intracellular serine/threonine protein kinase that plays a critical ro
260 AKT/PKB is a phosphoinositide-dependent serine/threonine protein kinase that plays a critical ro
263 AMP-activated protein kinase (AMPK) is a serine/threonine protein kinase that plays an important
264 nthase kinase 3 (GSK3) is a highly conserved serine/threonine protein kinase that plays important rol
266 that barren inflorescence2 (bif2) encodes a serine/threonine protein kinase that regulates auxin tra
267 grin-linked kinase (ILK) is an intracellular serine/threonine protein kinase that regulates cell adhe
268 Mammalian target of rapamycin (mTOR) is a serine/threonine protein kinase that regulates cell grow
270 malian target of rapamycin (mTOR) protein, a serine/threonine protein kinase that regulates ribosomal
274 vated protein kinases (PAKs) are a family of serine/threonine protein kinases that are activated by b
275 pha-kinases are a widely expressed family of serine/threonine protein kinases that exhibit no sequenc
276 Death-associated protein kinases (DAPK) are serine/threonine protein kinases that have an important
277 We explored the effects of siRNA on several serine/threonine protein kinases that have been implicat
278 p21-activated protein kinases (Paks) are serine/threonine protein kinases that phosphorylate Raf-
280 he protein kinase C (PKC) family consists of serine/threonine protein kinases that play important rol
281 omprise a family of evolutionarily conserved serine/threonine protein kinases that play multiple role
285 the nucleus and belong to the AGC family of serine/threonine protein kinases; the kinase domain of G
286 transcription factors, signalling molecules (serine/threonine protein kinases), thymosin beta 10 and
288 ce that the calcium and calmodulin-dependent serine/threonine protein kinase type II (CaMKII) is an i
290 e PKM isoforms in A549 cells lacking LKB1, a serine/threonine protein kinase upstream of AMPK, failed
291 orylation of ZEBRA protein at this site by a serine-threonine protein kinase was required for activat
292 ning of a human thymus cDNA library, PRP4, a serine/threonine protein kinase, was identified as a KLF
293 S6K1 is a member of the AGC subfamily of serine-threonine protein kinases, whereby catalytic acti
294 ing frame 36 (ORF36) of this virus encodes a serine/threonine protein kinase, which is designated the
295 The p21-activated kinases (PAKs) 1-3 are serine/threonine protein kinases whose activity is stimu
297 Akt, also known as protein kinase B, is a serine/threonine protein kinase with antiapoptotic activ
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