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1 1B heteroreceptors (receptors located on non-serotonergic neurons).
2 stry for tryptophan hydroxylase (a marker of serotonergic neurones).
3 h is the only Pcdhalpha isoform expressed in serotonergic neurons.
4 it reduces serotonin synthesis and firing of serotonergic neurons.
5 ) from the synaptic cleft after release from serotonergic neurons.
6 s that distinguish physiological subtypes of serotonergic neurons.
7 ound within brainstem areas known to contain serotonergic neurons.
8 ionary changes in the number and presence of serotonergic neurons.
9 behavior of immunohistochemically identified serotonergic neurons.
10 can substitute for the role of OCR-2 only in serotonergic neurons.
11 in 2 has selective actions on a subset of DR serotonergic neurons.
12 crossed with Tph2-Cre mice expressing Cre in serotonergic neurons.
13 a branch specific for the differentiation of serotonergic neurons.
14 of both channel genes affects other types of serotonergic neurons.
15 thelium, but is excluded from the nucleus of serotonergic neurons.
16 ior segment of the eye, and dopaminergic and serotonergic neurons.
17 ncy by controlling the rate of firing of the serotonergic neurons.
18 rom a developmental abnormality of medullary serotonergic neurons.
19 y activate dorsal raphe but not median raphe serotonergic neurons.
20 dence for potential direct actions of CRF on serotonergic neurons.
21 heartless is expressed specifically in serotonergic neurons.
22 atric disorders attributed to dysfunction of serotonergic neurons.
23 re alpha4-containing nAChRs are expressed by serotonergic neurons.
24 ectopic dorsal clusters of dopaminergic and serotonergic neurons.
25 ption factors to successfully generate human serotonergic neurons.
26 partial agonist displayed an effect only in serotonergic neurons.
27 rfascicular dorsal raphe, both areas rich in serotonergic neurons.
28 rgic, glutamatergic and, at lower frequency, serotonergic neurons.
29 se line to permit translational profiling of serotonergic neurons.
30 pletion and could not be restored by grafted serotonergic neurons.
31 ion of neurons in the adult brain, including serotonergic neurons.
32 (SERT, SLC6A4) to the synaptic terminals of serotonergic neurons.
33 c excision of p38alpha MAPK selectively from serotonergic neurons.
34 e largely not direct postsynaptic targets of serotonergic neurons.
35 ned place aversion to pain via inhibition of serotonergic neurons.
36 relatively homogenous DA population with few serotonergic neurons.
37 ague-Dawley rat to measure the activation of serotonergic neurons: (1) determination ex vivo of accum
38 are involved in controlling the activity of serotonergic neurons, 5-HT1A knockout mice had normal le
40 licited by direct optogenetic stimulation of serotonergic neurons activates HSF1 and upregulates mole
43 of Caenorhabditis elegans tph-1 in a pair of serotonergic neurons ADF during an aversive experience w
46 c excision of KOR from dopaminergic, but not serotonergic neurons, also blocked KOR-mediated disrupti
47 nduced tagged-5-HT(1A)R endocytosis in raphe serotonergic neurons and a portion of hippocampal neuron
48 xpressed in muscles that are postsynaptic to serotonergic neurons and are known to be required for th
49 mer's disease subjects showed markedly fewer serotonergic neurons and associated higher levels of neu
50 (3)ARs are coexpressed with SERT in midbrain serotonergic neurons and form a physical complex in A(3)
52 drives the differentiation of beta-cells and serotonergic neurons and imparts the shared ability to p
53 ysiological changes were driven by a loss of serotonergic neurons and reduced output as measured by h
54 oping mouse and chick neural tube, hindbrain serotonergic neurons and spinal glutamatergic V3 interne
55 ed facial motoneurons, catecholaminergic and serotonergic neurons and the ventral respiratory column
56 ntimate coordination between the activity of serotonergic neurons and their target cortical circuits.
57 ure, HA-5-HT(1B) receptors were expressed in serotonergic neurons and translocated to the forebrain.
59 3, possibly through their trophic effects on serotonergic neurons and/or motoneurons, may underlie se
60 xpressed in the ADF neurons but not in other serotonergic neurons, and act cell-autonomously to regul
61 nd eg: robo2/3 mutants lose Eg expression in serotonergic neurons, and robo2 and eg interact genetica
62 n the neocortex, modulatory dopaminergic and serotonergic neurons, and the striatal neurons that form
63 ockout mice (Lmx1bf/f/p), which lack central serotonergic neurons, and we report that opioid analgesi
64 s loss is specific to the HSN class as other serotonergic neurons appear to differentiate normally in
71 ha4-containing nAChRs, possibly expressed by serotonergic neurons, are involved in nicotinic-mediated
72 Our study revealed the cilium structure of serotonergic neurons as a trigger of regulated serotonin
73 ole in assessing the contribution of RTN and serotonergic neurons as well as glial cells to respirati
74 of putative chemosensitive glutamatergic and serotonergic neurons as well as marked astrocytic gliosi
76 ute to the respiratory stimulation caused by serotonergic neurons, but serotonin seems without effect
77 erminal neuronal identity in four classes of serotonergic neurons, but that the development of the AD
78 %) incorporated into approximately 50% of RO serotonergic neurons by injecting AAV2 DIO ChR2-mCherry
79 promoter-driven excision of p38alpha MAPK in serotonergic neurons (by Slc6a4-Cre or ePet1-Cre) or ast
80 so demonstrate that changes in the number of serotonergic neurons change larval swimming behavior.
82 ifferentiated in vitro into dopaminergic and serotonergic neurons, contractile cardiomyocyte-like cel
83 nucleus tractus solitarius (NTS) and caudal serotonergic neurons control the excitability of PBN neu
86 Paradoxically, the spiking activity of the serotonergic neurons decreased to a single burst at the
88 and roundabout3 (robo2/3) are necessary for serotonergic neuron differentiation and function indepen
89 f Robo2/3 is part of a signal that regulates serotonergic neuron differentiation and is transduced by
92 tocadherin alpha (Pcdhalpha) gene cluster in serotonergic neurons disrupts local axonal tiling and gl
93 The early specification of dopaminergic and serotonergic neurons during vertebrate CNS development r
94 g the serotonin (5-HT) content of identified serotonergic neurons embedded in a simple motor circuit.
95 We recently showed that acute inhibition of serotonergic neurons en masse blunts the CO(2) chemorefl
96 populations, we applied RC::PFtox to silence serotonergic neurons, en masse or a subset defined combi
101 the efficient generation of functional human serotonergic neurons from human fibroblasts as a novel t
104 he i5HT neurons expressed markers for mature serotonergic neurons, had Ca(2+)-dependent 5HT release a
108 y programs that control the specification of serotonergic neurons have been investigated by genetic m
110 provide a comprehensive map of the inputs to serotonergic neurons, highlighting the complexity and di
111 enteric nervous systems, SERT is located in serotonergic neurons; however, these neurons are not pre
112 ponded to 5-HT in a manner characteristic of serotonergic neurons (i.e., with activation of an inward
113 reased c-Fos expression in subpopulations of serotonergic neurons identified by either tryptophan hyd
115 te to the dysregulation of noradrenergic and serotonergic neurons implicated in the pathogenesis of M
117 directs a subset of these cells to generate serotonergic neurons in a particular location is unresol
119 selectively stimulating raphe obscurus (RO) serotonergic neurons in anesthetized mice and to test wh
120 as been observing the activity of identified serotonergic neurons in animals engaged in behavioral ta
121 han hydroxylase, we found that a majority of serotonergic neurons in both dorsal and caudal raphe cel
124 vironment and underscores neuroplasticity of serotonergic neurons in C. elegans under stress and stre
126 tudies have examined pathological changes in serotonergic neurons in depression, particularly in elde
127 duced KOR-mediated GIRK currents recorded in serotonergic neurons in DRN postsynaptically, without si
128 a method for obtaining dopaminergic (DA) and serotonergic neurons in high yield from mouse ES cells i
130 ntity, projection patterns, and functions of serotonergic neurons in juvenile and adult Aplysia are r
131 c and noradrenergic neurons or PET1-positive serotonergic neurons in mice decreased corresponding neu
132 osure is thought to selectively activate DRN serotonergic neurons in such a way as to render them tra
133 istry, we found changes in the activation of serotonergic neurons in the brainstem as well as evidenc
134 itch sensation, whereas mice lacking 5-HT or serotonergic neurons in the brainstem exhibit markedly r
136 e present study examines the distribution of serotonergic neurons in the caudal raphe involved in the
138 e neuronal density and neuritic pathology in serotonergic neurons in the dorsal raphe nuclei of elder
139 diated via the CRF type 2 (CRF2) receptor on serotonergic neurons in the dorsal raphe nucleus (DR).
140 ollable stress depend on hypersensitivity of serotonergic neurons in the dorsal raphe nucleus (DRN),
141 he expression of alpha4-containing nAChRs by serotonergic neurons in the dorsal raphe offered a means
144 ssion within the basolateral amygdala and in serotonergic neurons in the dorsal, ventrolateral, cauda
145 e if CRF2 receptor activation has effects on serotonergic neurons in the DR in conscious behaving rat
160 their differentiation into dopaminergic and serotonergic neurons in the presence of mitogen and spec
162 le, randomly presented sound pulses activate serotonergic neurons in the rat median raphe but not dor
163 suggesting that the LH innervates brainstem serotonergic neurons in the rostral ventromedial medulla
164 This removes the tonic inhibition of GABA on serotonergic neurons in the RVM, and activation of these
166 d a specific projection from NPVF neurons to serotonergic neurons in the ventral raphe nucleus (vRN).
167 sed the firing frequency of dopaminergic and serotonergic neurons in the ventral tegmental area and t
168 ty of cell types, including dopaminergic and serotonergic neurons in vitro and germ cells in vivo.
170 d laser photostimulation of ChR2-transfected serotonergic neurons increased respiratory frequency (fR
171 both short- and long-term activation of DRN serotonergic neurons induce antidepressant-like behavior
172 erm activation of dorsal raphe nucleus (DRN) serotonergic neurons induces robust behavioral responses
175 The dorsal swim interneurons (DSIs) are serotonergic neurons intrinsic to the central pattern ge
176 expression and regulation of these genes in serotonergic neurons invites speculation that they may m
177 e immune system on a specific group of brain serotonergic neurons involved in the pathophysiology of
178 ter example: the neuromodulatory effect of a serotonergic neuron is dependent on the interval between
179 neurons, but that the development of the ADF serotonergic neurons is regulated by an UNC-86-independe
183 es have suggested that activation of KORs on serotonergic neurons may be sufficient to mediate aversi
187 gic neuron activity: (1) a large fraction of serotonergic neurons modulated their tonic firing rates
188 er the DeltapH(i)/DeltapH(o) of 0.75 for non-serotonergic neurones (most of which are not chemosensit
191 assium transient current I(A) for a presumed serotonergic neuron of the rat dorsal raphe nucleus (DRN
197 duced p38alpha MAPK signaling cascade within serotonergic neurons of the dorsal raphe nucleus that me
204 ic neurons of the A7 and A5 cell groups, and serotonergic neurons of the nucleus raphe magnus (NRM).
206 The study found no evidence of a loss of serotonergic neurons or of neuritic pathology in the dor
207 nd saporin (anti-SERT-SAP; 1 microm) to kill serotonergic neurones, or (c) SP-SAP and anti-SERT-SAP t
213 rates of a subpopulation (19 of 70, 27%) of serotonergic neurons predominantly located in the ventra
218 is, in part, under the inhibitory control of serotonergic neurons projecting from the dorsal raphe nu
219 n neuronal than EC cell serotonin; moreover, serotonergic neurons promote development/survival of som
221 perpolarized the great majority (81%) of non-serotonergic neurons recorded extra- and intracellularly
224 r, the subsequent differentiation of central serotonergic neurons required both the suppression of VM
226 -like episodes correlated with the number of serotonergic neurons restored with orexin receptor expre
228 saicin-induced activation of dopaminergic or serotonergic neurons reversibly alters both physiologica
229 n the metazoan central nervous system (CNS), serotonergic neurons send projections throughout the syn
230 with the known arousal-dependent activity of serotonergic neurons, show that these receptors may medi
232 BS-NSC graft-derived catecholaminergic and serotonergic neurons showed remarkable long-distance axo
235 -Fos expression was greatly increased in DRN serotonergic neurons suggesting that OFF DRN-projecting
236 mbryoids also produced neuron-like cells and serotonergic neurons, suggesting that mesomeres are auto
238 s exclusion from GABAergic, cholinergic, and serotonergic neurons supports the notion that DNPI/VGLUT
239 pical plate and pharyngeal endoderm, and 4-6 serotonergic neurons that are confined to the apical pla
240 dicate that the BF shift can be modulated by serotonergic neurons that augment or reduce the BF shift
243 us is a major limbic target of the brainstem serotonergic neurons that modulate fear, anxiety, and le
244 he DRN are responsible for the inhibition of serotonergic neurons that occurs during natural AS.
245 r the genetic inactivation of Tph2 in caudal serotonergic neurons that project to the NTS protects ag
246 ns, egg laying, which is driven by a pair of serotonergic neurons, the hermaphrodite-specific neurons
248 ophila ventral nerve cord (VNC), each of two serotonergic neurons tiles distinct innervation patterns
249 odulatory actions at one synapse may allow a serotonergic neuron to play distinct roles at different
252 the hypothesis that the capacity of midbrain serotonergic neurons to release 5-HT at the MH is reduce
254 ), a specific marker of early differentiated serotonergic neurons, to study their migration via immun
255 amined how visceral motor neurons (VMNs) and serotonergic neurons, two neuronal subtypes, are sequent
257 reproducible and accurate method to profile serotonergic neurons under a variety of conditions and s
258 (Ucn 2) increases c-Fos expression in rat DR serotonergic neurons via actions on CRF2 receptors, we g
259 omically and functionally distinct subset of serotonergic neurons via activation of CRF2 receptors.
260 directly modulate gene expression in select serotonergic neurons via ER alpha and PR in female and m
261 ession of serotonin (5-HT) in axotomized non-serotonergic neurons via HIF-1, a hypoxia-inducible tran
262 laevis larvae modulates the specification of serotonergic neurons via regulation of expression of the
263 a mitogen-activated protein kinase (MAPK) in serotonergic neurons was found to be a critical mediator
264 A small percentage of spinally projecting serotonergic neurons was immunoreactive for the alpha3 s
265 lla, but the number of catecholaminergic and serotonergic neurons was not significantly reduced.
266 e with Fos and markers for noradrenergic and serotonergic neurons was used to examine if an intraplan
267 chniques and a novel lentiviral reporter for serotonergic neurons, we identified and overexpressed ke
268 l role of GLUA1-containing AMPA receptors in serotonergic neurons, we used the Cre-ERT2/loxP-system f
269 tro, and into mature-appearing pyramidal and serotonergic neurons weeks after being injected into the
270 in 1 receptor-positive neurons or descending serotonergic neurons were ablated before hyperalgesic pr
271 We sought to determine whether medullary serotonergic neurons were affected in multiple system at
273 Aergic and glutamatergic cells projecting on serotonergic neurons were found in the DRN and the adjac
276 the floor plate, including dopaminergic and serotonergic neurons, were greatly reduced in number or
277 F DRN-projecting RGCs predominately activate serotonergic neurons whereas ON DRN-projecting RGCs main
278 o regions receive a very small input from ML serotonergic neurons which, instead, heavily innervate t
279 d that the DeltapH(i)/DeltapH(o) of 0.69 for serotonergic neurones (which are stimulated by acidosis)
280 rominent at locations that contain medullary serotonergic neurones, which are chemosensitive in vitro
283 in contrast to activity in noradrenergic and serotonergic neurons, which is more tightly coupled to t
284 o long-term increases in the excitability of serotonergic neurons, which may represent a mechanism un
285 lls also activate dorsal raphe nucleus (DRN) serotonergic neurons, which project to the vicinity of t
286 Pet1 neurons may act downstream of Egr2-Pet1 serotonergic neurons, which were previously established
287 ntly augmented or reduced the activity of DR serotonergic neurons, while mice decided between differe
288 t with a loosely organized arousal system of serotonergic neurons whose components can be generally o
290 lularly under voltage clamp, were induced in serotonergic neurons with bath and microiontophoretic ap
294 stimuli via actions on a specific subset of serotonergic neurons within the dorsal raphe nucleus.
296 In this study, we use a pair of identified serotonergic neurons within the Drosophila olfactory sys
298 provide further support for the presence of serotonergic neurons within the median raphe nucleus tha
299 Furthermore, the basic branching pattern of serotonergic neurons within the neuropil remains unchang
300 greater neurofibrillary pathology and fewer serotonergic neurons would be found in the dorsal raphe
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