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1 neurotransmission (dopamine, benzodiazepine, serotonin receptors).
2 tes, and modulates signaling of the 5-HT(2A) serotonin receptor.
3 cell surface through an as yet unidentified serotonin receptor.
4 re transfected with 14 different isoforms of serotonin receptor.
5 in releasing hormone receptor, and the 5HT1a serotonin receptor.
6 BST, and of neuron populations that express serotonin receptors.
7 cular explanation for LSD's actions at human serotonin receptors.
8 functions and behavior by directly targeting serotonin receptors.
9 ly members for its interactions with defined serotonin receptors.
10 hich tryptamine-related agents bind at 5-HT6 serotonin receptors.
11 e polyomavirus and SV40, while JC virus uses serotonin receptors.
12 arinic M1 and M3, neurokinin, opioid KOP and serotonin receptors.
13 circuits are modulated via several different serotonin receptors.
14 of GABA-positive neurons are associated with serotonin receptors.
15 mRNAs, including the mRNAs of glutamate and serotonin receptors.
16 raphe nuclei, and expresses high density of serotonin receptors.
17 purposes, particularly in the modulators of serotonin receptors.
18 As, including the pre-mRNAs of glutamate and serotonin receptors.
19 from its mixed agonist/antagonist profile at serotonin receptors.
20 mine receptors, but instead by activation of serotonin receptors.
21 ntly enhances currents mediated by GABAA and serotonin receptors.
22 ogy of its recognition of the 5-HT1 class of serotonin receptors.
23 nge eating, and the contribution of specific serotonin receptors.
24 er insect amine receptors and the vertebrate serotonin receptors.
25 wo serotonin-related gene polymorphisms, the serotonin receptor 1A (5-HT1A) polymorphism at -1019C>G
28 arge family of S100 proteins, interacts with serotonin receptor 1B (5-HTR1B), modulates 5-HT1B recept
30 Furthermore, pharmacological inhibition of serotonin receptor 1B with SB224289, and of receptor 2A
31 d agonists for members of the 5-HT2 class of serotonin receptors, 2,5-dimethoxy-4-iodoamphetamine (DO
35 and identified tryptophan hydroxylase (Trh), serotonin receptor 2a (5HT2a), and the solute carrier 7-
36 xplored the roles of two of these receptors, serotonin receptor 2A (5HTR2A) and the D4 dopamine recep
37 ound that adrenoceptor alpha 2C (Adra2c) and serotonin receptor 2a (Htr2a) were the most highly expre
38 ms in the monoamine oxidase A (MAOA-LPR) and serotonin receptor 2A genes (rs6314) moderated the effec
40 (SCI) leads to a decrease in mRNA editing of serotonin receptor 2C (5-HT2CR) contributing to post-SCI
42 I-52 changes the alternative splicing of the serotonin receptor 2C pre-mRNA, which is different from
43 tophan hydroxylase 1 (Tph1, rs262731280) and serotonin receptor 3A (Htr3a, rs50670893) were associate
44 Noncoding variants in 5-hydroxytryptamine (serotonin) receptor 4 (HTR4) are associated with pulmona
45 affinity agonist of the 5-hydroxytryptamine (serotonin) receptor 4 that enhances motility in the gast
48 shown to be independent of their function as serotonin receptor 5-HT1B/1D agonist or cytostatic drug,
49 s for each of these receptors and found that serotonin receptor 5-HT2A is the sole molecular target f
51 n is a peripherally active antagonist of the serotonin receptor 5-HT3, and is marketed for prevention
52 monoamine oxidase A (serotonin catabolism), serotonin receptor 5-HT4, or mouse serotonin transporter
53 lactoseries tetrasaccharide c (LSTc) and the serotonin receptor 5-hydroxytryptamine (5-HT) receptor 5
58 reversal of hypothalamic NPY, alpha-MSH, and serotonin receptor (5-HT(1B)-receptor) enhancing FI.
59 n reuptake transporter (SERT) and the type 7 serotonin receptor (5-HT(7)) were expressed in human and
63 ypes: alpha7-nAChR, alpha4beta2-nAChR, and a serotonin receptor (5-HT3AR), along with a fluorescent r
64 y with CA1 pyramidal cells via activation of serotonin receptors (5-HT(1B)Rs), without affecting near
67 se to 5-hydroxytryptamine (5-HT), the type 1 serotonin receptors (5-HT1Rs) preferentially couple to t
69 emical localization of the crustacean type 1 serotonin receptor, 5-HT1crust, throughout the crayfish
71 tors, we have cloned and fully sequenced two serotonin receptors, 5-HT(1Mac) and 5-HT(2Mac), from the
72 cocorticoid receptor (GR) and an increase in serotonin receptor 5HT-1a, consistent with the decreased
76 ansport of two different cargoes (membranous serotonin receptor 6-green fluorescent protein [HTR6-GFP
77 mine (5-HT)), and we found that knockdown of serotonin receptor-6 (5-Htr6) expression or pharmacologi
78 E2 series prostaglandins and DHA influences serotonin receptor action by increasing cell membrane fl
79 tion, the intracellular signal mediating the serotonin receptor action in cholangiocytes was characte
81 We conclude that phrenic LTF requires spinal serotonin receptor activation and protein synthesis.
82 hat LTF of phrenic amplitude requires spinal serotonin receptor activation and spinal protein synthes
84 we show that presynaptic cAMP generation via serotonin receptor activation directly modulated hyperpo
88 syndrome patients with a clinically-approved serotonin receptor agonist (lorcaserin, Belviq(R)) and o
89 opropan-1-ol (6), an analogue of the 5-HT(2) serotonin receptor agonist 1-(4-bromo-2,5-dimethoxypheny
90 es a paradoxical response to the nonspecific serotonin receptor agonist m-chlorophenylpiperazine (mCP
92 ase inhibitor) and pergolide (a dopamine and serotonin receptor agonist) robustly reduced alcohol int
93 ith 5-nonyloxytryptamine (5-NT), a prototype serotonin receptor agonist, diminished reovirus cytotoxi
94 c acid diethylamide (LSD) is a non-selective serotonin-receptor agonist that was first synthesized in
95 ment for menstrual migraine is inconsistent, serotonin receptor agonists (triptans) provide acute rel
97 uts onto IO cells are strongly suppressed by serotonin receptor agonists as well as release of endoge
99 rain, attempts were made to identify 5-HT(2) serotonin receptor agonists with reduced propensity to p
100 esic agents (prostaglandin E2 and purine and serotonin receptor agonists) resulted in reduction in hy
101 of osteoblast numbers because inhibition of serotonin receptors alone in leukemic blasts did not aff
106 acts with 5-hydroxytryptamine(2A) (5-HT(2A)) serotonin receptors and attenuates receptor signaling vi
109 st notably, we found changes in dopamine and serotonin receptors and transporters (Dat1, Drd4, 5Htt,
110 ndent substituents, certain receptors (e.g., serotonin receptors) and monoamine transporters (i.e., s
111 The prototypical hallucinogen LSD acts via serotonin receptors, and here we describe the crystal st
112 00A10 (p11) was identified as a regulator of serotonin receptors, and it has been implicated in the e
113 nosine residues in a subset of glutamate and serotonin receptors, and this editing results in protein
115 s are compared with those obtained following serotonin receptor antagonism or episodic carotid sinus
116 1 receptor antagonists (NK1-RAs) and the new serotonin receptor antagonist (5HT3-RA) palonosetron.
118 longer recommends the combination of a 5-HT3 serotonin receptor antagonist and dexamethasone for the
119 SSRI fluoxetine and fluvoxamine and the 5-HT serotonin receptor antagonist cyproheptadine were conduc
121 icated healthy comparison women received the serotonin receptor antagonist metergoline as part of a d
122 ytryptamine affects phosphate excretion, the serotonin receptor antagonist methiothepin (20 microgram
124 or depotentiation, by DSI was blocked by the serotonin receptor antagonist methysergide and mimicked
126 ere occluded by serotonin and blocked by the serotonin receptor antagonist methysergide, suggesting t
128 ination of a 5-hydroxytryptamine-3 (5-HT(3)) serotonin receptor antagonist, dexamethasone, and aprepi
130 Hairless mice were injected with PAF or serotonin receptor antagonists and then exposed to solar
133 eatment of mammary epithelial membranes with serotonin receptor antagonists increased their transepit
137 ed as an affinity matrix in the screening of serotonin receptor antagonists with known affinities for
139 atients intolerant of or refractory to 5-HT3 serotonin receptor antagonists, neurokinin-1 receptor an
141 gy" and discuss how drugs targeting specific serotonin receptors are beginning to help treat a wide r
143 nervous system, and virtually all of the 15 serotonin receptors are expressed outside as well as wit
147 ychological processes, and drugs that target serotonin receptors are used widely in psychiatry and ne
148 are mediated through specific histamine and serotonin receptors, are independent of VEGF-A, and are
149 Antipsychotic drugs target dopamine and serotonin receptors as well as Kv11.1 potassium channels
150 ion of the 5-HT3 receptor, all of the cloned serotonin receptors belong to the G protein-coupled rece
151 rotonin content, serotonin uptake sites, and serotonin receptor binding measured in animal studies ar
153 riction was largely antagonized by selective serotonin receptor blockade, with little further antagon
154 the functional activity of not only 5-HT(2A) serotonin receptors but also selected Galpha(q)-coupled
155 s effect through the specific binding to the serotonin receptor, but recent research has suggested th
156 sulfonamides, sulfones) bind at human 5-HT6 serotonin receptors, but it has been difficult relating
157 regulate the expression of Htr2c, one of the serotonin receptors, by binding to its promoter, and the
158 -length N-acetylated peptides from the 5HT2c serotonin receptor C-terminal sequence, as well as for o
160 in systems and may play an etiologic role in serotonin receptor changes observed in patients with maj
161 ge of recent findings demonstrating that the serotonin receptor chaperone, p11, is an important molec
164 hment receptor for JCPyV and that the type 2 serotonin receptors contribute to JCPyV infection by fac
166 es, such as D2 dopamine receptors and 5-HT2A serotonin receptors, could evolve a mechanism that discr
168 uate their long-term effects on dopamine and serotonin receptors density in different brain areas.
170 n no reports demonstrating the expression of serotonin receptor dimers/oligomers on the plasma membra
172 The study provides valuable insight into serotonin receptor (dys)function in a limbic brain area.
174 affects diarrhea and anxiety via effects on serotonin receptors, enhanced intestinal repair, and sod
178 s are needed to determine whether postmortem serotonin receptor findings are also present in vivo and
179 LTF is serotonin dependent, and the relevant serotonin receptors for phrenic LTF are located in the c
180 ults indicate that a genetic perturbation of serotonin receptor function can modulate dentate gyrus p
182 he regulation of alternative splicing of the serotonin receptor gene in humans and other mammals.
183 dopamine receptor (Gs-coupled) and the 5HT1E serotonin receptor (Gi-coupled) mediated cellular prolif
184 gents, which block postsynaptic dopamine and serotonin receptors, have advantages over traditional an
185 rtex of Phf8 deficient mice and identify the serotonin receptors Htr1a and Htr2a as direct targets of
187 ilution phenotype was also observed with the serotonin receptor Htr6, fibrocystin PKHD1, and Arl13b.
188 This survey led to the discovery of the serotonin receptor HTR7 as a key mediator of serotonergi
190 on of a dopamine receptor effectively into a serotonin receptor illustrates the plasticity of GPCR si
191 onclusion, 5-HT7 receptor is a novel type of serotonin receptor implicated in hepatocyte proliferatio
192 tivity suggests that they do not bind to the serotonin receptor in a way such that the tricyclic naph
193 plicated the 5-hydroxytryptamine 2B (5-HT2B) serotonin receptor in mediating the heart valve fibropla
198 These findings suggest an important role of serotonin receptors in mediating the discriminative stim
199 This study aimed to determine levels of two serotonin receptors in subtypes of vascular dementia and
201 d to study the relationship between GABA and serotonin receptors in the central nucleus of the rat in
203 roxytryptamine (5-HT) 2A (5-HT2A) and 5-HT2C serotonin receptors in the hypothalamus were altered by
204 e differential roles of distinct families of serotonin receptors in this process and propose that reg
205 rally and directly activates SER-7, a type 7 serotonin receptor, in MC motor neurons in the feeding o
206 found that omega-3 fatty acids could prevent serotonin receptor-induced MAPK activation in hippocampa
211 ferences in biological activity suggest that serotonin receptor isoforms are very sensitive to subtle
212 onist propranolol (1) binds at rodent 5-HT1B serotonin receptors, it displays low affinity (Ki > 10,0
215 en little examination of the influences that serotonin receptors may play in modulating feeding withi
216 to play an important role in cognition, and serotonin receptors may provide a novel target for futur
217 gamma-aminobutyric acid, acetylcholine, and serotonin receptors, may also be erroneously modeled, an
218 c manipulation and western blot detection of serotonin receptors, measurements of serotonin, high-spe
220 rebrospinal fluid of sleep-deprived cats, on serotonin receptor-mediated responses were investigated
221 TGF-beta1 expression and activity because of serotonin receptor-mediated signal transduction with act
222 GPCRs, including histamine receptors, 5-HT (serotonin) receptors, muscarinic acetylcholine receptor,
223 ght to elicit their psychotropic actions via serotonin receptors of the 5-hydroxytryptamine 2A subtyp
224 previously that pharmacologic activation of serotonin receptors on motor neurons increases motor neu
226 lected genetic polymorphisms of dopamine and serotonin receptors or transporters were linked with agg
227 stablish their relationships to other insect serotonin receptors, other insect amine receptors and th
229 to dissect the specific function of distinct serotonin receptor populations across the life course, w
230 ography to determine whether aging decreases serotonin receptor populations in male Syrian hamsters.
234 l sites where 5-hydroxytryptamine2A (5-HT2A) serotonin receptors respond to the action of hallucinoge
235 vo many of the key molecular sites-including serotonin receptors, reuptake transporters, and enzymes-
236 gand-independent, constitutively active 5HT4 serotonin receptor (Rs1) to address how the massive incr
240 r and cellular target of citalopram, and the serotonin receptors SER-1 and SER-4 were strong genetic
241 of these aminergic receptors, including two serotonin receptors (ser-1 and ser-4), one tyramine rece
242 We found that non-endogenous agonists of the serotonin receptor share a particular IET spectral aspec
244 he antiviral properties of 5-NT suggest that serotonin receptor signaling is an important regulator o
245 ions of serotonin have been assigned through serotonin-receptor-specific drugs and mutants; however,
248 nscriptional repression includes the 5-Htr2a serotonin receptor, strongly associated with anxiety- an
250 y was used to advance the novel concept that serotonin receptor subtype 5-HT2C contributes critically
251 nputs from the basolateral nucleus (BLA) and serotonin receptor subtype 5-HT2CR in the BLA, but not C
252 t serotonin 2A is the predominant excitatory serotonin receptor subtype at hypoglossal motor neurons.
253 ferentially high affinities for a particular serotonin receptor subtype capable of stimulating mitoge
254 (2A) serotonin receptor is the most abundant serotonin receptor subtype in the cortex and is predomin
257 the distribution and function of the 5-HT5A serotonin receptor subtype, we generated knockout mice l
260 which activates cardiac afferents through a serotonin receptor (subtype 3,5-HT3 receptor) mechanism,
261 tered expression of each of three Drosophila serotonin receptor subtypes (d5-HT1A, d5-HT1B, and d5-HT
263 The effects of antagonists selective for serotonin receptor subtypes 2A, 2C, or 7 on intrinsic hy
264 alogs may permit the selective modulation of serotonin receptor subtypes and even have opposing effec
265 ols) were screened for activity at 11 cloned serotonin receptor subtypes by use of ligand-binding met
269 Initial experiments designed to clone novel serotonin receptor subtypes in the substantia nigra have
270 ceptor subtype 5-HT(1A) was one of the first serotonin receptor subtypes pharmacologically characteri
271 Sstr3 and Htr6 are the only somatostatin and serotonin receptor subtypes that localize to cilia, we h
272 ly characterize in SAVIC cultures the native serotonin receptor subtypes using specific agonists and
273 to suggest that the activation of different serotonin receptor subtypes within the feeding circuitry
280 ine2A (5-HT2A) receptor is a G(q/11)-coupled serotonin receptor that activates phospholipase C and in
281 amine receptor, and LGC-40 is a low-affinity serotonin receptor that is also gated by choline and ace
282 Salvinorin A had no actions at the 5-HT(2A) serotonin receptor, the principal molecular target respo
285 ty of the lamprey 5-hydroxytryptamine1b-type serotonin receptor to reduce excitatory postsynaptic cur
289 ts also support the development of selective serotonin receptor type 1A agonists for use as antidyski
291 t controlled by 5-HT(2)Rs must involve other serotonin receptor types and/or secondary signaling even
292 To this end we cloned all four known insect serotonin receptor types from Manduca (the Ms5HTRs).
293 lution room-temperature structure of a human serotonin receptor using sub-10-micrometer microcrystals
294 on of 100 graphics models of the human 5-HT6 serotonin receptor was constructed based on the structur
295 BTs to known antagonists of the dopamine and serotonin receptors, we explored the roles of two of the
296 pamine, tyrosine hydroxylase, and the 5-HT5A serotonin receptor were increased in the cerebral cortex
298 RETATION: Our findings suggest activation of serotonin receptors with lorcaserin may provide the firs
299 alpha1 noradrenergic (alpha1 NE), and 5-HT2 serotonin receptors within the pre-Botzinger complex (pr
300 cules tested had relatively low affinity for serotonin receptors, yet a preliminary screen indicated
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