コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 postsynaptic D2 antagonist, and inhibitor of serotonin transporter.
2 ectual disabilities the functionality of the serotonin transporter.
3 rmalin-induced pain, as did mice lacking the serotonin transporter.
4 abolism), serotonin receptor 5-HT4, or mouse serotonin transporter.
5 ts reuptake at dopamine, norepinephrine, and serotonin transporters.
6 ine D2/D3 receptors ([(11)C]raclopride), and serotonin transporter (11)C-N,N-dimethyl-2-(-2-amino-4-c
9 SIDS).Mice with a targeted disruption of the serotonin transporter (5-HTT) develop in the presence of
10 gical signaling in mouse models of disrupted serotonin transporter (5-HTT) function, a risk factor fo
12 ic blockade of monoamine oxidase A (MAOA) or serotonin transporter (5-HTT) has antidepressant and anx
15 caine self-administration at a high level of serotonin transporter (5-HTT) occupancy with no detectab
17 unoreactive (IR) with antibodies against the serotonin transporter (5-HTT) protein were widely distri
18 th are involved in serotonin synthesis), and serotonin transporter (5-HTT) were measured in the ventr
19 imaging with a radiotracer specific for the serotonin transporter (5-HTT), (11)C-McN5652, we found t
21 variations in the 5-hydroxytryptamine (5-HT; serotonin) transporter (5-HTT) gene are associated with
22 structural variants of the gene encoding the serotonin transporter [5-hydroxytryptamine transporter (
23 corresponding residues (R104E/E493R) in the serotonin transporter also rescues [(3)H](S)-citalopram
24 levels leading to the down-regulation of the serotonin transporter and a variety of 5-HT receptors, i
26 ed by platelet serotonin accumulated via the serotonin transporter and could be antagonized using ser
27 be single molecular interactions between the serotonin transporter and MFZ2-12 (a potent cocaine anal
28 functionally important Cl(-) binding site in serotonin transporter and other Cl(-)-dependent transpor
29 tion between microRNA 135 (miR135), and both serotonin transporter and serotonin receptor-1a transcri
30 involved in the pathogenesis of PAH such as serotonin transporter and tenascin-C was elevated in dis
31 18)F]MPPF, two PET radiotracers, marking the serotonin transporter and the 5-HT1AR, respectively.
33 ative affinity of the antidepressant for the serotonin transporter and to assess whether concomitant
35 May, 2016, were studied with tracers for the serotonin transporter and vesicular monoamine transporte
36 hibits both the dopamine transporter and the serotonin transporter, and simple chemical modifications
37 and interactions with dopamine transporter, serotonin transporter, and vesicular monoamine transport
38 erotonin reuptake inhibitors targeting brain serotonin transporters are first-line treatments for bip
39 MRN for tryptophan hydroxylase-2 (Tph2), the serotonin transporter, as well as 5-HT1A and 5-HT1B rece
40 croscopy to study the diffusion of the human serotonin transporter at the ER and the plasma membrane.
42 sease subgroup had significantly lower raphe serotonin transporter availability but less severe stria
43 Parkinson's disease had significantly lower serotonin transporter availability in the brainstem raph
45 on's disease patients and that reduced raphe serotonin transporter availability is associated with th
46 s and release, are downregulated in SAD, and serotonin transporter availability might be increased; h
49 d [11C]DASB binding potential as an index of serotonin transporter availability were acquired during
50 hy, markers of dopamine storage capacity and serotonin transporter availability, to investigate wheth
54 Future studies should investigate midbrain serotonin transporter binding as a predictor of suicidal
55 nt with postmortem work showing low midbrain serotonin transporter binding capacity in depressed suic
60 ding, VMAT2 binding, (18)F-FDOPA uptake, and serotonin transporter binding in multiple brain regions
62 ehavior and completed suicide, including low serotonin transporter binding in postmortem studies of c
64 rkinson's disease had significantly elevated serotonin transporter binding in the hypothalamus (compa
65 manifest Parkinson's disease show increased serotonin transporter binding in the striatum, brainstem
70 sion who attempt suicide have lower midbrain serotonin transporter binding potential compared with th
71 region (F1,10 = 0.83; P = .38), and midbrain serotonin transporter binding potential did not predict
74 el-based analysis localized further relative serotonin transporter binding reductions in the cingulat
75 atients with fatigue had significantly lower serotonin transporter binding than patients without fati
76 onin transporter promoter gene (5-HTTLPR) on serotonin transporter binding using in vivo imaging tech
80 s with bipolar disorder had 16% to 26% lower serotonin transporter BP(1) in the midbrain, amygdala, h
82 e inhibition, excellent selectivity over the serotonin transporter, but no selectivity over the dopam
84 ng PET, we assessed whether dopaminergic and serotonin transporter changes are similar in LRRK2 mutat
85 factor (BDNF), reduced Glut4, with unchanged serotonin transporter concentrations were noted in (F) (
86 y; on the other candidate genes, such as the serotonin transporter, continue to dominate in genetic s
87 er was significantly higher than that of the serotonin transporter, despite similar in vitro potencie
88 upport the hypothesis that inhibition of the serotonin transporter during neonatal life by an SSRI is
89 necessary to confirm that inhibition of the serotonin transporter during the neonatal period is suff
92 extent of down-regulation is potentiated by serotonin transporter function (IC50 of 2.3 +/- 1.0 muM,
93 associations between genetic variability in serotonin transporter function and stress-related psycho
94 patients seem to have upregulation of brain serotonin transporter function at the early phase of the
96 reuptake inhibitor, fluvoxamine, to inhibit serotonin transporter function in ovariectomized rats.
97 ch locus, supporting the notion of increased serotonin transporter functioning being pathogenetically
98 lymorphisms (5-HTTLPR and STin2 VNTR) of the serotonin transporter gene (5-HTT), we find strong evide
100 Polymorphisms in the promoter region of the serotonin transporter gene (5-HTTLPR) and exposure to ea
102 a polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) offering equivocal
103 a polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR), we found that ind
104 ed the hypothesis that a polymorphism in the serotonin transporter gene (locus, SLC6A4; variant, sero
105 etic variation in the promoter region of the serotonin transporter gene (serotonin transporter-linked
107 udies have reported associations between the serotonin transporter gene (SLC6A4) and alcohol, heroin,
108 hism (5HTTLPR) in the promoter region of the serotonin transporter gene (SLC6A4) and exposure to chil
110 ects in two candidate genes of interest--the serotonin transporter gene (SLC6A4) and the integrin bet
111 rphisms in the repeat upstream region of the serotonin transporter gene (SLC6A4) are associated with
112 R polymorphism in the promoter region of the serotonin transporter gene (SLC6A4) has been found to mo
114 nalyses of common functional variants of the serotonin transporter gene (SLC6A4), a long-standing OCD
115 rphism located in the promoter region of the serotonin transporter gene (SLC6A4), is implicated in sp
117 iry: variation in the promoter region of the serotonin transporter gene (SLC6A4; also known as 5-HTT)
119 idence of association between alleles of the serotonin transporter gene and pulmonary hypertension wa
120 e-environment interactions (GxE) between the serotonin transporter gene and stress on risk of depress
121 entifying two common genetic variants of the serotonin transporter gene and their association with in
126 igates whether a genetic polymorphism of the serotonin transporter gene moderates susceptibility to a
127 e is associated with brain morphology is the serotonin transporter gene polymorphism within the promo
128 rs1042173-TT (SLC6A4-LL/TT) genotypes in the serotonin transporter gene predicted a significant reduc
129 d that increased promoter methylation of the serotonin transporter gene predicted increased threat-re
130 re we show that a common polymorphism in the serotonin transporter gene relates to an accurate and ro
131 R, a functional promoter polymorphism of the serotonin transporter gene SLC6A4, influences cerebral c
132 The HTTLPR, a functional polymorphism of the serotonin transporter gene solute carrier family 6 (neur
133 s, carrying at least one short allele of the serotonin transporter gene was associated with a 26% hig
134 Individuals with 1 or 2 short alleles of the serotonin transporter gene were at higher risk for an in
135 We investigated polymorphic variation of the serotonin transporter gene, a biological candidate for p
137 methylation of the proximal promoter of the serotonin transporter gene, which predicts greater incre
138 in the transcriptional control region of the serotonin transporter gene, which renders carriers of th
142 renaline transporter (NAT) gene, and not the serotonin transporter genes, in dopaminergic cells, whic
143 s meta-analysis yielded no evidence that the serotonin transporter genotype alone or in interaction w
144 so differentially affected, as a function of serotonin transporter genotype, functional connectivity
148 spite the well-established role of the human serotonin transporter (hSERT) in the treatment of depres
151 e photoaffinity ligands (PALs) for the human serotonin transporter (hSERT) were synthesized based on
152 SLC6 family of proteins, including the human serotonin transporter (hSERT), utilize Na(+), Cl(-), and
157 t in the relative importance of dopamine and serotonin transporters in the abuse-related-effects of c
160 E2, the density of fibers immunoreactive for serotonin transporter innervating the auditory midbrain
163 s in humans mirror the phenotypic effects of serotonin transporter knockout in mice, highlighting the
164 he amygdala and cingulate cortex between the serotonin transporter knockout mouse, a genetic animal m
165 Parkinson's disease; and (ii) whether raphe serotonin transporter levels correlate with severity of
166 rs increased SLC6A4 transcription, increased serotonin transporter levels in brain and other tissues
168 e investigated with SPECT using the dopamine/serotonin transporter ligand (123)I-N-omega-fluoropropyl
169 pothesis: 1) observational studies about the serotonin transporter linked polymorphic region (5-HTTLP
170 ing the report of an interaction between the serotonin transporter linked polymorphic region (5-HTTLP
171 ied the influence of genetic variance in the serotonin transporter linked polymorphic region (5-HTTLP
175 er region of the serotonin transporter gene (serotonin transporter-linked polymorphic region [5-HTTLP
176 less than 150 nucleotides centromeric of the serotonin transporter-linked polymorphic region indel kn
177 1A (5-HT1A) polymorphism at -1019C>G and the serotonin transporter LS polymorphism, have been reporte
178 ta suggest that differential function of the serotonin transporter may mediate differential response
179 ed decreases in tryptophan hydroxylase 2 and serotonin transporter mRNA in the dorsal raphe dorsalis
183 cupancy was extrapolated (85%); however, low serotonin transporter occupancy prevented similar seroto
185 and from mice with PH induced by hypoxia or serotonin-transporter overexpression (SM22-5HTT(+) mice)
186 nomethyl-phenylsulfaryl)-benzonitrile (DASB) serotonin transporter PET imaging was performed in a sub
187 onin signaling in the form of a common human serotonin transporter polyadenylation polymorphism (STPP
191 association of the STin2 and/or the 5-HTTLPR serotonin transporter polymorphisms in adult males with
192 elationship of a functional variation of the serotonin transporter promoter gene (5-HTTLPR) on seroto
196 hypothesis that the S allele of the 5-HTTLPR serotonin transporter promoter region is associated with
197 was no association between genotypes of the serotonin transporter promoter region polymorphism and s
198 of serotonin and serotonergic receptors are serotonin transporter protein (SERT or soluble carrier p
199 of a genetic polymorphism (5-HTTLPR) in the serotonin transporter protein gene on the likelihood tha
200 ions in TnaT-D268S, in wild type TnaT and in serotonin transporter provide direct evidence for the in
202 ing the dopamine transporter (DAT(-/-)), the serotonin transporter (SERT(-/-)), or both (DAT(-/-)SERT
203 of the alternate conformation in a mammalian serotonin transporter (SERT) (a member of the same trans
206 ion tomography for two serotonergic markers: serotonin transporter (SERT) and serotonin 1A (5-HT1A) r
207 ial smooth muscle cell proliferation via the serotonin transporter (SERT) and serotonin can induce pu
209 y measure the interaction forces between the serotonin transporter (SERT) and the S- and R-enantiomer
210 f juvenile grasshopper mice labeled with the serotonin transporter (SERT) antibody, revealing a strik
212 We have developed a homology model for the serotonin transporter (SERT) based on the crystal struct
214 ptoms was associated with change in cerebral serotonin transporter (SERT) binding following intervent
217 ty of using (11)C-DASB for quantification of serotonin transporter (SERT) density and affinity in viv
218 lthio)benzylamine ((11)C-HOMADAM) imaging of serotonin transporter (SERT) density in healthy control
220 of intracellular solute-binding to the human serotonin transporter (SERT) expressed in HEK-293 cells.
221 panes 1-4 were synthesized as ligands of the serotonin transporter (SERT) for use as positron emissio
223 ould be via HPA axis-dependent impairment of serotonin transporter (SERT) function, the high-affinity
225 k and reports on the optimization of DAT and serotonin transporter (SERT) functional assays, as well
226 identified genetic interactions between the serotonin transporter (SERT) gene and ITGB3, which encod
228 Antagonist dissociation experiments on the serotonin transporter (SERT) have also unveiled the exis
229 t years, a number of PET studies imaging the serotonin transporter (SERT) have been used and provided
230 opane (betaFEpZIENT, 1) was synthesized as a serotonin transporter (SERT) imaging agent for both posi
232 oimaging, and genetic findings implicate the serotonin transporter (SERT) in autism spectrum disorder
247 opane (ZIENT), is a high affinity, selective serotonin transporter (SERT) ligand that has shown promi
249 rotonin (5-HT) into neurons and other cells, serotonin transporter (SERT) modulates the action of 5-H
250 rported anti-addiction properties, inhibited serotonin transporter (SERT) noncompetitively by decreas
251 opiate withdrawal, has been shown to inhibit serotonin transporter (SERT) noncompetitively, in contra
253 This 5-HT signal was not potentiated by the serotonin transporter (SERT) or the noradrenaline transp
257 lytic method to derive accurate and reliable serotonin transporter (SERT) receptor parameters with (1
263 ability in IBS-D including a decrease in the serotonin transporter (SERT) which is also seen followin
264 zing enzyme tryptophan hydroxylase (TPH) and serotonin transporter (SERT) with semiquantitative immun
265 lore structure-activity relationships at the serotonin transporter (SERT), a series of (+/-)-4- and 5
266 isms regulating disulfide bond formation for serotonin transporter (SERT), an oligomeric glycoprotein
267 finities for the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transpo
268 bind to the dopamine transporter (DAT), the serotonin transporter (SERT), and the norepinephrine tra
269 cocaine: the dopamine transporter (DAT), the serotonin transporter (SERT), and the norepinephrine tra
270 f its DAT affinity were only observed at the serotonin transporter (SERT), dopamine D2-like, and sigm
272 n, (123)I-FP-CIT has modest affinity for the serotonin transporter (SERT), predominantly represented
273 nity for DAT and robust selectivity over the serotonin transporter (SERT), whereas affinity improved
283 subsequently causes the translocation of the serotonin transporter (SERT, SLC6A4) to the synaptic ter
287 s (K(i) = 1.81 nM) with DAT selectivity over serotonin transporters (SERT; 989-fold), norepinephrine
291 Channel properties are also attributed to serotonin transporters (SERTs); however, SERT regulation
293 ential interactions between these factors on serotonin transporter (slc6a4) mRNA expression, we inves
294 ters of the SLC6 family, including the human serotonin transporter (SLC6A4), is critical for efficien
296 norepinephrine transporter (SLC6A2, NET) and serotonin transporter (SLC6A4, SERT) genes and remission
297 f the maternal polymorphism, 5HTTLPR, in the serotonin transporter, SLC6A4, coupled with prenatal str
298 activation of p38alpha MAPK translocated the serotonin transporter to the plasma membrane and increas
299 ubstituents on the 7-position with the human serotonin transporter Tyr175 versus dopamine transporter
300 and intermediate, but not low, affinity for serotonin transporter were associated with upper gastroi
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。