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3 A significant interaction between baseline serum LDH and treatment was observed; oblimersen signifi
4 at 18 months (AUC = 0.813) than did baseline serum LDH levels alone for prediction of progression-fre
6 In multivariate analysis, a high baseline serum LDH level was associated with decreased progressio
9 ncreased survival in patients whose baseline serum LDH was not elevated (median overall survival, 11.
10 overall or event-free survival, whereas both serum LDH and stage influenced both overall and event-fr
13 DH >two-thirds the upper limit of normal for serum LDH) were absent (LR, 0.04; 95% CI, 0.02-0.11).
15 PFS in patients (n = 158 per arm) with high serum LDH, a potential marker of hypoxia, PFS was longer
17 ion of baseline clinical variables including serum LDH and imaging findings with progression-free and
19 rotein >0.5, a ratio of pleural fluid LDH to serum LDH >0.6, or pleural fluid LDH >two-thirds the upp
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