ライフサイエンスコーパス: serum concentration

1 rquartile range (IQR) increment of each PFAS serum concentration.

2 nced as fast as 48 h in culture, even at low serum concentration.

3 ing occurred at the highest 17beta-estradiol serum concentration.

4 n tumor surgery were evaluated for NT-proBNP serum concentration.

5 n by detergents is annulled at physiological serum concentrations.

6 nts fed soy formula, and they result in high serum concentrations.

7 en had no estrogenic activity at therapeutic serum concentrations.

8 Y-specific ELISA allowed measurement of GNLY serum concentrations.

9 treatment that result in clinically relevant serum concentrations.

10 ndirect exposure contributing to 45% of PFOA serum concentrations.

11 onditions, to treatment with lithium (target serum concentration, 0.80-0.99 mEq/L) or divalproex (tar

12 two technicians, who had much lower initial serum concentrations (10-17 ng/mL), were strongly influe

13 We analyzed neuron-specific enolase serum concentrations 3 days after nontraumatic in-hospit

14 f thrombocytopenia (11.9%) and increased AST serum concentration (4.3%).

15 high-sensitivity C-reactive protein (hsCRP) serum concentration - a marker of systemic inflammation.

16 Serum concentrations after vaginal dosing were 56-fold l

17 avelength light were reduced with increasing serum concentration and cell confluency.

18 relationships between quartile of infliximab serum concentration and efficacy at these time points (P

19 renal clearance of cobalt increased with the serum concentration and was, on average, lower in women

20 stimate individual perfluorooctanoate (PFOA) serum concentrations and assess the association with pre

21 letion decreased chemokine (CC-motif) ligand serum concentrations and circulating Ly6C(high) monocyte

22 We measured MASP-1 serum concentrations and endogenous MASP-1/C1-INH comple

23 correlation between the increasing antibody serum concentrations and the charge-transfer resistance

24 We investigated children's PFC serum concentrations and their associations with asthma-

25 A drinking-water concentrations on estimated serum concentrations and their reported epidemiological

26 This study measured serum concentrations and urinary excretion of TMAO in a

27 e (5-MTHF) in human skin can be predicted by serum concentrations and whether there are differences i

28 redictions of milk PBDE concentrations using serum concentrations appear to be a valid method for est

29 determine whether alpha-tocopherol intake or serum concentrations are associated with fracture risk i

30 udy, we evaluated PTX3 tissue expression and serum concentration as a biomarker to discriminate prost

31 We propose that elevated Ang II serum concentrations, as occur in patients with congesti

32 The primary endpoint was trough serum concentration at cycle five, with a non-inferiorit

33 e curve at steady state (AUCtau) and maximum serum concentration at steady state (CmaxSS) at cycle 4,

34 king, and body mass index corrected for, PCB serum concentrations at baseline were not predictive of

35 Elevated IL-10 serum concentrations at clinical presentation of SaB wer

36 ent, and higher interleukin (IL)-5 and IL-10 serum concentrations at day 15 of treatment than those w

37 Serum concentration biomarkers of several vitamins and c

38 o the following regression (R(2)) values for serum concentration biomarkers: folate, 0.49; vitamin B-

39 obal HSA function is related not only to its serum concentration, but also to the preservation of its

40 inty can substantially change estimated PFOA serum concentrations, but results in only minor impacts

41 + and PH2+ was inversely related to chemical serum concentrations; but after adjustment for confounde

42 se findings suggest that a reduction in PBDE serum concentrations cannot yet be detected following th

43 e, as well as cell culture conditions (e.g., serum concentration, cell confluency, medium refreshment

44 The median maximum serum concentration (Cmax), area under the curve from 0-

45 part of MDR tuberculosis treatment have low serum concentrations compared with adults receiving 400

46 The predicted estradiol serum concentrations (convoluted from in vitro skin perm

47 CXCL9 serum concentration correlated with the modified Localiz

48 Lonafarnib serum concentrations correlated with HDV RNA change (r(2

49 Pooled serum-concentration correlated significantly with increa

50 ENG serum concentration decreased in all patients, more mark

51 After cessation of breastfeeding, all serum concentrations decreased.

52 MBL genotype frequencies and MBL serum concentrations did not differ between patients and

53 Cytochrome c serum concentrations do not have diagnostic but substant

54 ate possible reverse causality (i.e., higher serum concentrations due to decreased excretion after me

55 We studied PCB serum concentrations during and after weight loss and th

56 f type I sensitization and correction of its serum concentrations enhances the benefit of specific im

57 sing cumulative PFOA exposure (sum of yearly serum concentration estimates), most notably among males

58 s the placenta with rapidly detectable fetal serum concentrations following maternal administration;

59 ther novel features include published plasma/serum concentrations for 1278 proteins along with a sepa

60 yroid compared to euthyroid cats have higher serum concentrations for some of the investigated PBDEs

61 eation data) were compared with the observed serum concentrations for the respective products.

62 (interquartile range) p,p'-DDT and p,p'-DDE serum concentrations for VHEMBE cohort participants were

63 The increases in adiponectin serum concentrations, gene and protein expression occurr

64 A neuron-specific enolase serum concentration greater than 90 mug/L predicted Cere

65 Brain natriuretic peptide (BNP) serum concentration has been shown to be a preoperative

66 At cycle five, the geometric mean trough serum concentration in patients given subcutaneous ritux

67 Our objectives were to characterize PBDE serum concentrations in a New England cohort and assess

68 Furthermore, we evaluated PTX3 serum concentrations in an independent set of patients w

69 MBL serum concentrations in CDI and AAD subjects were determ

70 uces brain glucose uptake and increases VEGF serum concentrations in lean mice.

71 Mean cobalt whole blood and serum concentrations in men were 20 mug/L (range: 12-33

72 s detected in the percentage increase in PCB serum concentrations in MetS+ compared with MetS- subjec

73 Mean 25(OH)D3 serum concentrations in patients with HBV DNA <2,000 ver

74 Finally, we measured CCL2 serum concentrations in patients with SM and found that

75 xS: The HR was 1.42 (95% CI: 1.08, 1.87) for serum concentrations in tertile 2 versus tertile 1, and

76 Low 25(OH)D serum concentrations in the first trimester of pregnancy

77 his study evaluated common organic pollutant serum-concentrations in children, as it related to behav

78 mpared with the third trimester, lamotrigine serum concentration increased an average of 154% within

79 In the presence of daclizumab, IL-2 serum concentrations increased and IL-2R bg signaling in

80 An neuron-specific enolase serum concentration less than or equal to 17 mug/L exclu

81 Neuron-specific enolase serum concentrations less than or equal to 17 mug/L argu

82 ey had severe alpha1 antitrypsin deficiency (serum concentration <11 muM) with a forced expiratory vo

83 f populations with low-level TCDD exposures (serum concentrations <10 pg/g lipid) and heterogeneous,

84 duced increase in KLOTHO gene expression and serum concentrations may translate into beneficial clini

85 ) and dichlorodiphenyldichloroethylene (DDE) serum concentrations measured in VHEMBE mothers when the

86 rmulation that achieves equivalent rituximab serum concentrations might improve convenience and save

87 0 ng/mL and 4.0 (1.6, 10.4) for women with a serum concentration of >/=10 to <20 ng/mL (P-trend = 0.0

88 The peak serum concentration of 100 mg S44819 correlated directly

89 The serum concentration of adipokines was determined by Lumi

90 In addition, we show that increasing serum concentration of cell media results in greater cyt

91 fection caused a significant increase in the serum concentration of CXCL-10, compared with the concen

92 There was a 50% reduction in the serum concentration of CXCL10 (IP-10), CCL22 (MDC), CCL1

93 Sitagliptin reduced the serum concentration of DPP-4.

94 Serum concentration of EVs distinguished patients with m

95 SF and serum concentration of histamine was higher in RA, compa

96 HLA genotype therefore might affect the serum concentration of IgG4, and increased IgG4 might be

97 Pegylation prolongs the serum concentration of IL-10 without changing the immuno

98 Relationships between serum concentration of infliximab and efficacy outcomes

99 Serum concentration of interleukin 22 associated with di

100 Serum concentration of lipofuscine (LPS), malondialdehyd

101 ponse ratio was linearly proportional to the serum concentration of MeP-adducted peptide (MeP-P) over

102 rvival benefit was associated with decreased serum concentration of pro-inflammatory cytokines, reduc

103 The serum concentration of resistin was higher in overweight

104 The serum concentration of study targets was assessed throug

105 The serum concentration of the active metabolite N-desethyla

106 Maximum serum concentration of the radiolabeled antibody was 22.

107 B-12 was associated with a 177% increase in serum concentration of vitamin B-12 (641 compared with 2

108 Maternal CPS-specific antibody serum concentrations of >/= 1 mug/mL at the time of deli

109 -age z score (HAZ) was associated with lower serum concentrations of 1) omega-3 (n-3) and omega-6 (n-

110 Serum concentrations of 20(OH)D3 and 22(OH)D3 were only

111 Analysis of serum concentrations of 21 ETN-treated AS patients with

112 udinal self-reported cART adherence data and serum concentrations of 24 biomarkers of inflammation an

113 iry products results in significantly higher serum concentrations of 25(OH)D and a significantly grea

114 ally effective in increasing and maintaining serum concentrations of 25-hydroxyvitamin D [25(OH)D], p

115 No significant interaction between serum concentrations of 25-hydroxyvitamin D and s-retino

116 response varied among patients, approximate serum concentrations of 41 mug/mL infliximab at week 8 o

117 HAZ was associated with significantly higher serum concentrations of 5 biomarkers related to cigarett

118 d associations between maternal and paternal serum concentrations of 63 POPs, comprising five major c

119 Parental serum concentrations of 9 organochlorine pesticides, 1 p

120 ant, average annual percent increases in the serum concentrations of all three PBDEs over the four-ye

121 those previous studies which suggested that serum concentrations of alpha-synuclein and its antibodi

122 was attenuated after adjustment for BMI and serum concentrations of alpha-tocopherol (HR: 1.16; 95%

123 Low intakes and low serum concentrations of alpha-tocopherol are associated

124 Orlando stage (slit-lamp biomicroscopy), and serum concentrations of amiodarone and N-desethylamiodar

125 Serum concentrations of antibodies against outer surface

126 Plasma and serum concentrations of apoAII-ATQ/AT were measured in t

127 ospective birth cohort, we measured maternal serum concentrations of BDE-47 and other PBDE congeners

128 Median maternal serum concentrations of BDEs 28 and 47 were 1.0 and 19.1

129 y outcomes were hemoglobin concentration and serum concentrations of beta-carotene, retinol-binding p

130 h care system in the U.S. Pacific Northwest, serum concentrations of beta-HCH and mirex were positive

131 increased endometriosis risk associated with serum concentrations of beta-hexachlorocyclohexane (HCH)

132 ng feces as a noninvasive matrix to estimate serum concentrations of brominated flame retardants (BFR

133 according to hyperinsulinaemia status using serum concentrations of C-peptide, a marker of insulin s

134 expression, which inversely correlated with serum concentrations of C-reactive protein (CRP) and cli

135 Baseline serum concentrations of C-reactive protein (CRP), interl

136 Counterintuitively, elevated serum concentrations of C-X-C chemokine 10 (CXCL10), a p

137 HANES) to compare self-reported SLT use with serum concentrations of cotinine, a metabolite of nicoti

138 Estimation of GFR from serum concentrations of creatinine and cystatin C has be

139 We examined the associations of maternal serum concentrations of DDT and DDE during pregnancy wit

140 h a 1-SD increase in ln-transformed maternal serum concentrations of DDT, PBDE congeners 28 and 183,

141 er Screening Trial.We examined prediagnostic serum concentrations of diet-related metabolites in a ne

142 y as an indirect reflection of CAP activity, serum concentrations of different inflammation markers,

143 We evaluated the association between serum concentrations of eight PFCs, including perfluoroo

144 It was found that serum concentrations of eltoprazine increased in a dose-

145 Serum concentrations of factor H (FH), factor I (FI), C9

146 wer liver triacylglycerol content, and lower serum concentrations of fatty acids and beta-hydroxybuty

147 first investigated the relationship between serum concentrations of FGF2 and individual differences

148 e and mineral metabolism, including elevated serum concentrations of fibroblast growth factor-23 (FGF

149 ct of this exposure pathway, we examined the serum concentrations of five major PFASs in a Faroese bi

150 Higher serum concentrations of folate and vitamin B-12 before A

151 investigate associations between intakes and serum concentrations of folate and vitamin B-12 or serum

152 Serum concentrations of four PBB and four PCB congeners

153 We assessed serum concentrations of Glial Fibrillary Acidic Protein

154 re was no significant intervention effect on serum concentrations of glucose, adiponectin, CRP, or IL

155 to diets were assessed by measuring fasting serum concentrations of glucose, insulin, insulin-like g

156 se and that Msr1-deficient mice had elevated serum concentrations of glucose-6-phosphate isomerase.

157 DeltaDC mice showed lower serum concentrations of IFN-beta and IL-12p40, but norma

158 me NTS risk allele was associated with lower serum concentrations of IFNgamma (p=0.02) at presentatio

159 Maternal and CB serum concentrations of IgE, IgG anti-IgE, and IgG anti-

160 cell 2 cytokines and is associated with high serum concentrations of IgE.

161 We investigated serum concentrations of IGF-1 and IGFBP-3 and their mola

162 Maternal serum concentrations of IgG anti- Ia, -Ib, -III and -V p

163 Maternal and CB serum concentrations of IgG anti-IgE/IgE ICs were highly

164 filtration in affected tissues, and elevated serum concentrations of IgG4.

165 d septic human neonates demonstrate elevated serum concentrations of IL-18 compared with adults.

166 lammasome components that together increased serum concentrations of IL-18.

167 36 in atherosclerotic mice resulted in lower serum concentrations of IL-1beta and accumulation of cho

168 In this article, we demonstrate elevated serum concentrations of IL-1beta in both mice with exper

169 lls and precursors in bone marrow as well as serum concentrations of IL-7, Flt3L, SCF, and ThPO to th

170 Higher baseline serum concentrations of IL22, a cytokine whose expressio

171 ) T cells to become 'memory-like', increased serum concentrations of immunoglobulin E (IgE) and cause

172 In addition, renal mRNA and serum concentrations of inflammatory cytokines IL-1beta,

173 1 and ACT-2) to assess relationships between serum concentrations of infliximab and outcomes of adult

174 Serum concentrations of infliximab are associated with e

175 Median serum concentrations of infliximab at weeks 8, 30, and/o

176 pective evaluation of the value of measuring serum concentrations of infliximab should be performed b

177 We compared serum concentrations of infliximab with outcomes of 728

178 not observe a correlation between fecal and serum concentrations of infliximab.

179 e export of iron occurs concurrent with high serum concentrations of interferon gamma (IFN-gamma) and

180 Dose-proportional increases in serum concentrations of lanadelumab were observed; the m

181 quality of dietary fat is known to influence serum concentrations of LDL cholesterol in children.

182 ng afamin revealed increased body weight and serum concentrations of lipids and glucose.

183 etabolic syndrome (MetS) are associated with serum concentrations of liver enzymes; however, fundamen

184 MNADK-deficient patients, such as increased serum concentrations of lysine and C10:2 carnitine.

185 study, we assessed the relationship between serum concentrations of mannose-binding lectin, mannose-

186 Serum concentrations of MBL were determined using a comm

187 tive breast cancer (144 cases).Prediagnostic serum concentrations of metabolites related to alcohol,

188 Serum concentrations of most acylcarnitines, glycerophos

189 on of B-1 cells, which resulted in increased serum concentrations of natural IgM and dysregulated hom

190 le linear regression analyses indicated that serum concentrations of nearly all PFASs declined on ave

191 CSF and serum concentrations of NfL correlated with disease seve

192 CSF and serum concentrations of NfL were significantly correlate

193 This is the first study linking maternal serum concentrations of nicotinamide and related metabol

194 l exposure and health in Taiwan, we measured serum concentrations of nine PFASs and four thyroid horm

195 In adjusted models, each doubling of serum concentrations of non-ortho PCBs and TEQ was assoc

196 ancer was two times as likely among men with serum concentrations of oxychlordane in the highest quar

197 In this study the serum concentrations of oxytocin peptide were measured i

198 Serum concentrations of p,p' isomers of DDT and DDE were

199 To investigate whether serum concentrations of PBDE were associated with thyroi

200 DDT, PBDE congeners 28 and 183, and paternal serum concentrations of PBDE-183 and PCB-167.

201 We previously reported that median serum concentrations of PBDEs and their metabolites (OH-

202 Serum concentrations of PBDEs were measured using gas ch

203 Serum concentrations of PBDEs were not strongly associat

204 clinic in 2011-2012 (n = 36) and now compare serum concentrations of PBDEs, OH-PBDEs, polychlorinated

205 Our study indicates that the increment in serum concentrations of PCBs does not differ according t

206 Estimated historical exposures and serum concentrations of perfluorooctanoic acid (PFOA) ha

207 sociation between breastfeeding and maternal serum concentrations of perfluorooctanoic acid (PFOA), p

208 Previous studies have found serum concentrations of PFAS to be positively associated

209 Serum concentrations of PFASs and antibodies generally d

210 gible cohort members) who were 13 years old, serum concentrations of PFASs and of antibodies against

211 stfeeding was associated with lower maternal serum concentrations of PFOA (-3%; 95% CI: -5, -2%), PFO

212 reased renal phosphate reabsorption, and low serum concentrations of phosphate (inorganic phosphorus,

213 Increased serum concentrations of plant sterols, including stigmas

214 Each 2-SD increase in serum concentrations of polybrominated diphenyl ether-28

215 Serum concentrations of polybrominated diphenyl ethers (

216 Diabetes prevalence in relation to serum concentrations of polychlorinated biphenyl (PCB) c

217 Serum concentrations of polychlorinated biphenyls (PCBs)

218 Here we tested whether the relative serum concentrations of putatively neuroprotective (kynu

219 Increased fracture risk at high intakes and serum concentrations of retinol (s-retinol) have been ob

220 ANCOVA, adjusting for inflammation, baseline serum concentrations of retinol and beta-carotene, and s

221 und no effect on hemoglobin concentration or serum concentrations of retinol-binding protein and prea

222 under the time-concentration curves and peak serum concentrations of rifampin showed a more than prop

223 similar to her usual diet and 2) to evaluate serum concentrations of select nutrients as potential bi

224 In this work we present serum concentrations of several classes of POPs (polybro

225 The arithmetic mean serum concentrations of several PCB congeners decreased

226 sulfonamide) and paternal (PCBs 172 and 195) serum concentrations of several POPs were statistically

227 P450 3A4 (CYP3A4) activity, and can decrease serum concentrations of sex hormones.

228 substances (PFASs) is associated with lower serum concentrations of specific antibodies against cert

229 mined the associations between prediagnostic serum concentrations of sRAGE or N-(carboxymethyl)-lysin

230 By contrast, serum concentrations of tetra-, penta-, and hexa-BDEs we

231 m associations found can be used to estimate serum concentrations of tetra-decaBDEs from feces concen

232 Niacin increased serum concentrations of the anti-inflammatory adipokine,

233 he formula protein becomes important because serum concentrations of the essential amino acids should

234 Similarly, pancreatic mRNA and serum concentrations of the inflammatory cytokines IL-1B

235 The serum concentrations of the metabolite N-desethylamiodar

236 oratory tests of thyroid function (including serum concentrations of the pituitary hormone thyrotropi

237 Elevated serum concentrations of the vasoactive protein endotheli

238 paraben (MPB), and triclosan] and urine and serum concentrations of their respective biomarkers.

239 The serum concentrations of these factors were measured usin

240 seful thyroid function biomarkers, including serum concentrations of thyroid-stimulating hormone (TSH

241 perthyroidism, autoimmune thyroiditis (AIT), serum concentrations of thyroid-stimulating hormone (TSH

242 harmonization of measurement procedures for serum concentrations of thyroid-stimulating hormone are

243 Although we detected no changes in serum concentrations of thyroid-stimulating hormone or f

244 Brain-dead patients had higher serum concentrations of TNF and IL-6 and increased TNF p

245 egorized into 5 groups according to baseline serum concentrations of total 25(OH)D <30, 30 to <50, 50

246 nts, while two copies were related to higher serum concentrations of total and dust mite-specific IgE

247 The serum concentrations of total testosterone, sex hormone-

248 Serum concentrations of traditional persistent organic p

249 Similarly, the arithmetic mean serum concentrations of tri- to hexaBDEs were lower in N

250 The present study measured serum concentrations of ubiquitin C-terminal hydrolase (

251 duals consuming a vegan diet had the highest serum concentrations of uric acid compared to meat eater

252 uantitative food frequency questionnaire and serum concentrations of uric acid were measured.

253 uid chromatography/tandem mass spectrometry, serum concentrations of various SL metabolites in 406 pa

254 Allergen-blocking capacity correlated with serum concentrations of Ves v 5-specific IgG4 which rose

255 Serum concentrations of vitamin A and 25-hydroxyvitamin

256 Serum concentrations of wheat and rice sIgG and sIgG4 ar

257 ses indicated effect modification by initial serum concentrations of zinc and vitamin C.

258 Median (Q1,Q3) digoxin serum concentration on day 7 was 1.1 (0.7,1.5) ng/mL on

259 uPAR, with a mean reduction of 37 +/- 12% of serum concentration per session.

260 ndard deviation increases in log-transformed serum concentrations ranged between 18% and 21% for PCB

261 ith the increase in calcium salts-phosphates/serum concentration ratio.

262 High neuron-specific enolase serum concentrations reliably predicted poor outcome at

263 ations to those study findings or to typical serum concentrations requires pharmacokinetic modeling.

264 Increasing serum concentration resulted in a steep fall in monocyte

265 TGF-beta1 serum concentration significantly decreased in tricuspid

266 ects without proteinuria and a normal sC5b-9 serum concentration survived (P < .01).

267 had 5-7 times higher p,p'-DDT and p,p'-DDE serum concentrations than those who never lived in a hom

268 neous rituximab 1600 mg would achieve trough serum concentrations that were non-inferior to those ach

269 bcutaneous rituximab 1600 mg achieved trough serum concentrations that were pharmacokinetically non-i

270 ower than the present accepted physiological serum concentration threshold value (40 ppt) and commerc

271 1 days (CE) or carboplatin at area under the serum concentration-time curve 4 on day 1 plus etoposide

272 ion to receive carboplatin at area under the serum concentration-time curve 5 on day 1 plus etoposide

273 harmacokinetic endpoints were area under the serum concentration-time curve at steady state (AUCtau)

274 on in population-level p,p'-DDT and p,p'-DDE serum concentrations under five hypothetical interventio

275 sociation between cancer and cumulative PFOA serum concentration using proportional hazards models.

276 nes has been measured at clinically relevant serum concentrations using the label-free technique of s

277 developed a method to rapidly quantify their serum concentrations, using antibody-labeled and energy-

278 t 19 microg.mL(-1) (a clinical target trough serum concentration), vancomycin was mainly monomeric (<

279 We investigated whether 25-hydroxyvitamin D serum concentration was a modifiable risk factor for ear

280 IL-10 serum concentration was higher in SaB patient mortality

281 25-hydroxyvitamin D (25(OH)D) serum concentration was measured in 9838 individuals wit

282 While serum concentration was similar for all four polyamides

283 he exception of PFHxS, the downward trend in serum concentrations was evident for all PFASs across al

284 OH) and metabolism to PFOA) exposure to PFOA serum concentrations was investigated using a dynamic on

285 No differences in benznidazole serum concentration were found.

286 In women, mean cobalt whole blood and serum concentrations were 53 mug/L (range: 6-117 mug/L)

287 The infant PFOA and PFOS serum concentrations were 6% (95% CI: 1, 10%) and 4% (95

288 PBDE serum concentrations were associated with socioeconomic

289 PFAA serum concentrations were available for all mothers and

290 Adult p,p -DDE and total PCB serum concentrations were both associated with significa

291 eated cell culture medium containing various serum concentrations were determined.

292 Retrospective yearly PFOA serum concentrations were estimated for each participant

293 linically, median matrix metalloproteinase-8 serum concentrations were higher in patients with sepsis

294 )D-deficient mice, OVA-specific IgE and IgG1 serum concentrations were increased compared with contro

295 Steady state olaratumab serum concentrations were reached during cycle 3 with me

296 Maternal and infant serum concentrations were regressed on duration of breas

297 igenic site 412 to 423 were elicited but the serum concentrations were too low to neutralize the viru

298 f antibodies to adalimumab or the adalimumab serum concentration when assessing patients' Psoriasis A

299 sion significantly correlated mean pollutant serum-concentration with the probability of diagnosis of

300 wed that MH6-vaccinated rats had higher METH serum concentrations, yet lower brain METH concentration