ライフサイエンスコーパス: serv(e|es|ed|ing) as(| a| the) substrate(|s) for

1 s in VPg on the abilities of the peptides to serve as substrates for 3D(pol).

2 contains a CAAX motif at the C-terminal that serves as a substrate for a series of post-translational

3 product, 2-methylgeranyl diphosphate, which serves as the substrate for a subsequent cyclization rea

4 The glutamine residue that serves as a substrate for activated factor XIII becomes

5 purine- and pyrimidine-based nucleotides can serve as a substrate for actomyosin mechanics, but with

6 in double-stranded RNA or in pre-mRNAs that serve as substrates for ADAR1 or ADAR2.

7 -allo-isoleucine covalently tethered to CmaA serves as the substrate for additional enzymes in the CM

8 ATP can then modulate KATP channels, serve as a substrate for adenylyl cyclase, and possibly

9 est that lecticans in extracellular matrices serve as substrate for adhesion and migration of cells e

10 In addition, NAD also serves as a substrate for ADP-ribosylation of a number o

11 tter delineation of the atrial myopathy that serves as the substrate for AF and thromboembolic compli

12 uple to a G-protein-coupled receptor and may serve as substrates for agonist-induced G-protein activa

13 cetylmuramyl-peptidyl derivatives 2a and 2c, served as substrates for AmpD with a k(cat)/K(m) of >10(

14 identification of the cardiac ion channel(s) serving as substrate for AMPK not only would provide ins

15 nd present evidence suggesting that RetS may serve as a substrate for another sensor kinase.

16 terconnected in that a product of one enzyme serves as a substrate for another.

17 logical condition in which aldehydes or NADH serve as substrate for AOs.

18 The ability of 3-MedUMP to serve as a substrate for Asn 229 mutants shows that the

19 olic intermediates UDP-GalNGc and UDP-GlcNGc serve as substrates for assembly of most major classes o

20 city of cortical organization and that could serve as a substrate for associative learning, direct mu

21 Because dual AV node pathways serve as the substrate for AV node reentrant tachycardia

22 AKAP15) bound to the DCT, is hypothesized to serve as the substrate for beta-adrenergic regulation in

23 The ability of Tn7 recombination products to serve as substrates for both the limited gap repair requ

24 This NDP-sugar served as a substrate for both GtfC and GtfD in the pres

25 2-hydroxy derivatives, which are expected to serve as substrates for C-glycosylation.

26 slated beta subunit, but not alpha or gamma, serves as a substrate for carboxylmethylation.

27 rified eIF4G, demonstrating that eIF4G could serve as a substrate for caspase 3.

28 esidues are both necessary and sufficient to serve as substrate for CDC34-dependent ubiquitination.

29 king three Cdk phosphorylation sites did not serve as a substrate for Cdc34p-dependent ubiquitination

30 inetically inactive as an enzyme; instead it serves as a substrate for Cdk2/Cyclin E.

31 The ECM maintains tissue integrity and can serve as a substrate for cell migration.

32 s may depend on the layer of BM available to serve as a substrate for cell reattachment.

33 in tyrosine residues 596, 636 and 701 do not serve as substrates for cellular kinases.

34 d activated to its CoA thioester, which then serves as a substrate for chalcone synthase.

35 Recently we have shown that FnbA serves as a substrate for coagulation factor XIIIa and u

36 ds to ground state, suggesting that SCN- may serve as a substrate for Compound II.

37 esterification into the acceptor rather than serving as substrates for continued beta-oxidation.

38 domain, composed of multiple heptad repeats, serves as a substrate for cross-linking by transglutamin

39 NG E3 ligases suggested that CLC-1 seemed to serve as the substrate for cullin 4A (CUL4A) and 4B (CUL

40 We demonstrate that SAP 155 serves as a substrate for cyclin E-cdk2 in vitro and tha

41 Moreover, Ser(67) of inhibitor-1 serves as a substrate for cyclin-dependent kinase 5 in t

42 ng residue in ARL1, abolished the ability to serve as substrate for cytohesin-1 or C-1Sec7.

43 ived from convergent overlapping transcripts serves as a substrate for Dcr-2.

44 mport UDP-glucose into the vacuole, where it serves as substrate for de novo glycogen synthesis, thro

45 cture on the macronuclear-destined sequences serves as the substrate for de novo telomere addition, w

46 ethyl-lysine residues recognized by HP1 also serve as substrates for deacetylation by HDACs, the inte

47 In principle, any long dsRNA could serve as a substrate for Dicer.

48 H3K9ac serves as a substrate for direct binding of the SEC, as

49 sociate with the Dlar cytoplasmic domain and serve as substrates for Dlar in vitro, suggesting that t

50 termini, resulting in termini that can again serve as substrates for DNA ligases.

51 first processed to a 3'-ssDNA overhang that serves as a substrate for DNA strand exchange.

52 property of altered NF content protecting by serving as substrates for dysregulation of any NF kinase

53 ), which is not a direct purinergic agonist, serves as a substrate for ecto-ribosylation reactions th

54 Succinyl-CoA did not serve as a substrate for either enzyme.

55 ctance infrared spectroscopy, are adapted to serve as substrates for electrochemical ATR surface enha

56 Alu sequences may serve as substrates for elevated HR during cell prolifer

57 n lambda plm1, replication intermediates may serve as substrates for encapsidation.

58 These products served as substrates for enyne ring-closing metathesis a

59 ocking out available conformations which may serve as substrates for enzyme systems that limit oral b

60 olyunsaturated fatty acids, anandamide could serve as substrate for enzymes such as lipoxygenases and

61 urons in the early visual pathway that could serve as the substrate for establishing cortical represe

62 nctional RecA to bind peptide sequences that serve as substrates for eukaryotic caspases, and regulat

63 vealed that isolated alpha C fragments could serve as a substrate for factor XIIIa.

64 a central role in maintaining hemostasis by serving as a substrate for factor XIIIa and plasmin.

65 product of the ACC reaction, and acetyl CoA serve as substrates for FAS to synthesize palmitic acid.

66 cardial right ventricular outflow tract scar serving as a substrate for fast VT in high-level enduran

67 ubstrate for RL, and coelenterazine does not serve as a substrate for FL either in cell culture or in

68 rough P450scc side-chain cleavage, which may serve as a substrate for further conversions into hydrox

69 ylic acid cycle for the production of ATP or serves as substrate for glutathione synthesis.

70 ants influenced less due to their ability to serve as substrates for glycogen synthase kinase 3, whic

71 y lack the glycosylation island, they cannot serve as substrates for glycosylation.

72 logically active, we tested their ability to serve as substrates for glycosyltransferases.

73 e to the formation of lipid peroxides, which serve as substrates for GPX-1.

74 olonized by endolithic phototrophic biofilms serving as a substrate for grazing epifauna, where scrap

75 s gel and consists of glycoproteins that can serve as the substrate for growth and chemotaxis of B. p

76 program, revealing novel targets that might serve as substrates for hCds1/Chk2 or Chk1 kinase activi

77 However, an N-terminal Ser served as a substrate for Hhat, but not the Drosophila m

78 unded by 229-kb direct repeats that probably served as substrates for homologous recombination.

79 The ability of OH-PCBs to serve as substrates for human cytosolic sulfotransferase

80 hat putrescine upregulates p35 expression by serving as a substrate for hypusine modification of eIF5

81 ity of I kappa B alpha and I kappa B beta to serve as substrates for IKKs and help provide a possible

82 ells from L. monocytogenes-infected mice can serve as substrates for in vitro cross-presentation of b

83 onal differentiation, synapse formation, and serve as a substrate for information processing.

84 lar ISG15 is IFN-alpha/beta-inducible not to serve as a substrate for ISGylation-dependent antiviral

85 in to cross-linked peptidoglycan, which also serves as the substrate for its glycyl-glycine endopepti

86 sticity in MIo and SIo occurring in parallel serves as a substrate for linking sensation and movement

87 Alternatively, polyunsaturated (PU)-NAEs may serve as substrates for lipid oxidation.

88 ian small proline-rich proteins was shown to serve as a substrate for mammalian transglutaminases.

89 absence of an electron donor, H(2)O(2) could serve as a substrate for MauG-dependent TTQ biosynthesis

90 for one cycle of beta-oxidation rather than serving as a substrate for membrane lipid synthesis.

91 We propose that oscillation-induced EPSPs serve as a substrate for memory, whose expression either

92 s a ubiquitous hydrocarbon compound that can serve as substrate for microbial growth.

93 f polyubiquitin chains but, importantly, can serve as a substrate for mono-ubiquitin-dependent proces

94 ne and N-1-(1-deoxy-D-mannityl)-L-asparagine served as substrates for MOP oxidoreductase.

95 ether the OT encodes natural reinforcers and serves as a substrate for motivational information proce

96 Methylated MMCP then serves as a substrate for MT2-A, which methylates CoM.

97 in the RCR decrease the ability of 4E-BP1 to serve as a substrate for mTORC1 in vitro and in vivo.

98 We now show that NO serves as a substrate for multiple members of the mammal

99 dies showed that glutathione derivatives can serve as substrates for NaAtm1 and that its overexpressi

100 N(tz)AD(+) and N(tz)ADH serve as substrates for NADase, which selectively cleave

101 The capacity of these peptides to serve as substrates for Neisseria gonorrhoeae (NG) PBP3

102 e phosphorylation sites in beta-tubulin that serve as substrates for NEK6 in vitro.

103 ssembling peptide (sapeptide) scaffolds that serve as substrates for neurite outgrowth and synapse fo

104 boratories, have shown that 2-fluoro-ATP can serve as a substrate for nine enzymes that are represent

105 Arginine is an amino acid that serves as a substrate for nitric oxide synthase and argi

106 use/human COX-2, but only ibuprofen arginate served as a substrate for NOS.

107 TP and Mg-ATP can bind to distinct sites and serve as substrates for nucleotide hydrolysis.

108 ncogenes and double-stranded breaks that can serve as substrates for oncogenic chromosomal translocat

109 cleoprotein filament conformation and either serve as substrates for or competitively inhibit hydroly

110 We found that Asn-Bpa-Thr peptides served as substrates for OST and that photoactivation of

111 rly as elongated blades with striations, and served as substrates for other mineral products.

112 HIC and I-mfa can serve as substrates for P-TEFb.

113 ubstrate, other nonhistone proteins can also serve as substrates for P/CAF.

114 PU.1 served as a substrate for p300 and was acetylated on lys

115 important role in cell cycle progression by serving as a substrate for p34(cdc2) kinase.

116 a consensus site for p38 phosphorylation and serves as a substrate for p38 MAP kinase in vitro.

117 serine/threonine-phosphorylated, and FHF can serve as a substrate for p38delta in vitro.

118 K targeting of serine 73, whereas serine 409 serves as a substrate for p90 Rsk-1.

119 hrough the generation of new 3' termini that serve as substrates for PAP I.

120 These molecules served as substrates for PBP5.

121 wn about the nature of the polypeptides that serve as substrates for peptidogenic cytosolic proteases

122 -oxidation system to dicarboxylic acids that serve as substrates for peroxisomal beta-oxidation.

123 ymes to toxic dicarboxylic acids (DCAs) that serve as substrates for peroxisomal beta-oxidation.

124 ne to inducing resistance and less likely to serve as substrates for Pgp efflux.

125 subunits examined, only alpha 12 and alpha z served as substrates for phosphorylation by various isof

126 Injection of several other peptides that serve as substrates for PKA also reversibly inhibited ne

127 stored the ability of the alpha1S subunit to serve as a substrate for PKC.

128 p47phox-GST fusion protein, that p47phox can serve as a substrate for PKCdelta in vitro.

129 This suggests that SM-alpha actin may serve as a substrate for PKCepsilon in lung fibroblasts

130 ar and cytosolic extracts, and both proteins serve as substrates for PKR in vitro.

131 To determine if osteopontin could serve as a substrate for platelet adhesion, we measured

132 xamined whether Cyr61 and Fisp12/mCTGF could serve as substrates for platelet adhesion.

133 of a population of associated RNAs that can serve as substrates for polyadenylation.

134 The MUC5AC glycopeptide failed to serve as a substrate for ppGaNTase-T6 after modification

135 wth by stabilizing misfolded proteins, which serve as substrates for prion conversion.

136 osphorylation motif at these serine residues served as substrates for protein kinase C in vitro.

137 eceptor agonists, whereas microbial proteins serve as substrates for proteolytic cleavage and MHC II

138 amily involved in synapse formation may also serve as substrates for PS/gamma-secretase-like intramem

139 concentrated at the surface of Listeria and serves as the substrate for PtdIns(3,4,5)P3 production,

140 m is tyrosine phosphorylated in vivo and can serve as a substrate for PTPRO in vitro.

141 extensive tracts of single-stranded DNA that serve as substrate for Rad51.

142 nally silent, nonspecific retinal inputs can serve as a substrate for rapid plasticity in the adult.

143 Surface-assembled CF was also found to serve as a substrate for receptor methylation in a react

144 tinol-binding protein type 2 and the complex serves as a substrate for reesterification of the retino

145 y, therefore, that the nucleus accumbens may serve as a substrate for reinforcement learning.

146 ce (terminal resolution site [TRS]) that can serve as a substrate for Rep-mediated nicking activity.

147 n which a plasmid containing the DNA adducts served as the substrate for repair enzymes in whole-cell

148 N(tz)AD(+) also serves as a substrate for ribosyl transferases, includin

149 The requirements for pro-sigmaK to serve as a substrate for RIP were investigated by produc

150 e, d-luciferin (a substrate for FL) does not serve as a substrate for RL, and coelenterazine does not

151 ntisense oligonucleotides (ASOs) designed to serve as substrates for RNase H1 were inactive in the he

152 NF181 even prior to signaling, and Bcl10 can serve as a substrate for RNF181 E3 ligase activity in vi

153 s without major detrimental side-effects may serve as a substrate for selection response during speci

154 1024) were required for SIRT1 repression and served as substrates for SIRT1 deacetylation.

155 etocyclopropane products are demonstrated to serve as substrates for SN2, SN2', and aldehyde cycloadd

156 binding site that can exist on proteins that serve as substrates for Src family kinases and provide a

157 t both versicolorin A and versicolorin B can serve as substrates for StcU, resulting in a branched pa

158 enerated during the course of this work will serve as substrates for subsequent analysis of the NovP

159 tant efficiently formed dienone cycloadducts serve as substrates for subsequent Nazarov cyclizations

160 -tryptophan (cAATrp), the tetramic acid that serves as substrate for subsequent prenylation and oxida

161 ngly, PAPS has to be provided by plastids to serve as a substrate for sulfotransferase reactions in t

162 ded by observations that both NADPH and NADH serve as substrates for superoxide production in vascula

163 ting of a chirped diffraction grating, which serves as a substrate for surface plasmon-enhanced optic

164 the antiapoptotic transcription factor STAT3 serves as a substrate for SYK tyrosine kinase both in vi

165 Telomeres protect chromosome ends and serve as a substrate for telomerase, a reverse transcrip

166 e a long single strand TG(1-3) tail that can serve as a substrate for telomerase.

167 ions and prevent the loss of terminal DNA by serving as a substrate for telomerase, they are essentia

168 impairment of LTP induction, but could also serve as a substrate for the cognitive symptoms that com

169 Only compound 3 was found to serve as a substrate for the enzyme.

170 same mother cell in the developing neocortex serve as a substrate for the formation of this highly sp

171 homologue from Bacillus subtilis (BsIDH) to serve as a substrate for the kinase and phosphatase acti

172 eu-1 do not measurably effect its ability to serve as a substrate for the L/F-transferase, and the di

173 ative endogenous cannabinoid ester, also may serve as a substrate for the transporter.

174 In addition, paxillin was found to serve as substrate for the adhesion-activated c-Abl kina

175 , since the mutated phospholamban form could serve as substrate for the calcium-calmodulin-dependent

176 a model in which prefolded dimers of apoSOD1 serve as substrate for the CCS copper chaperone.

177 rast with the ability of free lipoic acid to serve as substrate for the dihydrolipoyl dehydrogenase (

178 Conversely, 1,2-diacylglycerol does not serve as substrate for the neutrophil ceramide kinase.

179 elated but nonidentical 19-bp sequences that serve as substrates for the activity of the Tn5 transpos

180 akin, and possibly other structural proteins serve as substrates for the attachment of ceramides by e

181 dified DNA oligonucleotides were designed to serve as substrates for the bacteriophage T4 helicase, D

182 e that members of the SRC coactivator family serve as substrates for the enzymatic coactivator coacti

183 honic acids were tested for their ability to serve as substrates for the enzyme nucleoside monophosph

184 al afferent terminals in the aortic arch may serve as substrates for the future investigation of aort

185 liganded cellular retinoid binding proteins serve as substrates for the metabolism of some retinoids

186 o targets and regulates non-coding RNAs that serve as substrates for the miRNA-processing pathway.

187 romoter-proximal short RNAs are unstable and serve as substrates for the nuclear exosome.

188 ids (tryptophan, phenylalanine and tyrosine) serve as substrates for the pathway, and it involves bra

189 e found to be comparable in their ability to serve as substrates for the peroxidase activities of PGH

190 e speculate that the small SLACS transcripts serve as substrates for the production of siRNAs to regu

191 , and 6 and Saccharomyces cerevisiae ARF2 to serve as substrates for the rat liver Golgi membrane gua

192 dorant-induced mucosal activity patterns may serve as the substrate for the perception of odorant qua

193 ex was active as a retinoblastoma kinase and served as a substrate for the Cdk-activating kinase Cak.

194 Thus oleate at sn-1 and sn-2 positions served as substrate for the delta12 desaturase and is co

195 fied by co-chromatography with standards and served as substrate for the sulfolipid synthase associat

196 The resulting co(I)rrinoids served as substrates for the ATP:co(I)rrinoid adenosyltr

197 d that retained introns, high in GC content, served as substrates for the formation of transcriptiona

198 se, with the exception of the O-phosphonate, served as substrates for the reverse enzymatic reaction,

199 to these extracts showed that these proteins served as substrates for the ubiquitin-proteasome pathwa

200 ine, the ROSA26 conditional reporter (R26R), serves as a substrate for the Cre-mediated recombination

201 This modification serves as a substrate for the elongation of anchored Lys

202 Myelin basic protein serves as a substrate for the kinase and enables further

203 an N-acyl-D-asparagine prodrug scaffold that serves as a substrate for the periplasmic D-amino peptid

204 the TCR-zeta protein in target T lymphocytes serves as a substrate for the proteolytic activities tha

205 ads to the formation of 3'-tailed DNA, which serves as a substrate for the strand exchange protein Ra

206 AA, in turn, serves as a substrate for the synthesis of leukotrienes

207 Finally, since arachidonic acid serves as the substrate for the synthesis of inflammator

208 ible prostaglandin endoperoxide synthases by serving as a substrate for the enzymes' peroxidase activ

209 IP2) is critical for T lymphocyte activation serving as a substrate for the generation of second mess

210 ride diphospholipids (Lipid II and Lipid IV) serve as substrates for these PGTs, but the product dist

211 razide, a compound that had been reported to serve as a substrate for this enzyme, was complicated by

212 but the tetrasaccharide maltotetraose cannot serve as a substrate for this phosphorylysis reaction.

213 ted age-related changes in the BFCN that may serve as a substrate for this vulnerability.

214 ntain Rad, and in vitro both Rad and Gem can serve as substrates for this kinase.

215 Amphetamines and certain antidepressants may serve as substrates for this transporter and elicit chro

216 Porphyrinogens serve as substrates for three heme biosynthetic enzymes.

217 We found that matriptase serves as a substrate for TMPRSS2 in mediating this proi

218 In this study, we show that pro-CpU serves as a substrate for transglutaminases.

219 orms large, high-quality crystals that could serve as the substrate for transistor fabrication.

220 ulation of misaminoacylated tRNAs that could serve as substrates for translation or for MurM.

221 D)J recombination in a lymphoid precursor to serve as substrates for translocations with chromosomes

222 minepentaacetate (DTPA) chelating linker and served as substrates for two types of enzymes: one with

223 dherin, alpha-catenin, or APC protein and to serve as a substrate for tyrosine kinase.

224 The skin is well-suited to serve as a substrate for vaccination strategies.

225 , we show that the dopamine D1A receptor can serve as a substrate for various GRKs and that GRK-phosp