ライフサイエンスコーパス: several

1 tion reaction of ketones in conjunction with several 3-bromoindole derivatives.

2 beta-Thalassemia is associated with several abnormalities of the innate immune system.

3 Here we identify several acetylation sites of the influenza A virus nucle

4 totagmin that suggest a structural basis for several activities required for fusion, including a C2B

5 However, there are several additional diagnoses that should be considered i

6 he basis of a number of experimental models, several alternative cell types have been proposed as the

7 Several analogues showed subnanomolar affinity and excel

8 Several analytical methods have been proposed for analyz

9 Quantitative analysis of clonal abundance in several anatomic sites identified 2 types of anatomic as

10 wledge about fecal microbiome composition in several animals and imperfect marker specificity and sen

11 ulators of the hedgehog pathway have yielded several antagonists of the GPCR-like smoothened receptor

12 nately, the leprosy bacillus is sensitive to several antibiotics.

13 It is believed to be the cellular target of several antimycobacterial compounds; however, evidence f

14 charomyces cerevisiae is a common yeast with several applications, among which the most ancient is wi

15 more attractive candidate than graphene for several applications, for example, as mechanical reinfor

16 We investigate several approaches to interpret the phase images includi

17 Using fMRI, we identified several areas of parietal, occipitotemporal, and frontal

18 In particular, we identified several arginine residues that interact with the polyani

19 tba-6 also influences several aspects of extracellular vesicle biology, includ

20 es have implied the association of IRF5 with several autoimmune diseases, including systemic lupus er

21 the PV membrane (PVM) becomes decorated with several autophagy markers, including LC3 (microtubule-as

22 mmunity has been shown to be highly toxic in several bacteria and is believed to be one of the major

23 While their study evaluated several biases, it does not account for all.

24 e cross-talk between nitric oxide and H2S in several bilogical contexts.

25 gattii were compared by MaxEnt software with several bioclimatic conditions as well as with soil char

26 We also analyze the impact of several biological and technical factors on the quality

27 ffects mechanistic and functional aspects of several biological processes such as autophagy, inflamma

28 In cardiac myocytes, there are several Ca(2+) -sensitive potassium (K(+) ) currents suc

29 25, is a marker in the clinical diagnosis of several cancers and currently is the best serum-based tu

30 n analysis, we identify associations between several candidate genes and agronomically important trai

31 s to obtain novel antibodies typically yield several candidates capable of engaging a given target.

32 Using in vitro cultures of several cell types found in the heart, we delineate the

33 llyl intermediate.Reduction of allenes poses several challenges in terms of chemo-, regio- and enanti

34 While several chemokine receptors and ligands control multiple

35 s, and fasting blood glucose) and identified several cis-eGenes (ALDH2 for systolic and diastolic blo

36 lassification was evaluated and ranked using several classification quality metrics.

37 Several clever structural features underlie this amazing

38 core splicing factors have been reported in several clonal disorders, including cancers.

39 We also identified several CNVs that include known ASD genes (SHANK3, CDH10

40 These findings may partly be attributable to several cohort-specific factors associated with breastfe

41 esolution mass spectrometry instruments with several collision energies, we proved the method's platf

42 e organic compounds in SOA is measured using several complementary techniques including aerosol mass

43 d find that the prochiral reagent can sample several complexation geometries during the lifetime of a

44 We found that several components of the PAF1 transcription elongation

45 neuron involves the sex-specific scaling of several components of the synaptic vesicle machinery, in

46 Several computer programs have now been designed to pred

47 er adults with depression more commonly have several concurrent medical disorders and cognitive impai

48 Several contact, but not conformational, mutp53s enhance

49 ipennis is a serious invasive forest pest in several countries including the United States, Canada, a

50 Although several Cyp inhibitors have been reported in the literat

51 by CD4(+) T cells are being elucidated, with several cytokines implicated.

52 Several databases were searched from inception up to Feb

53 , vacuolization of astrocytes, followed over several days by astrogliosis.

54 obial susceptibility, but they often require several days of turnaround time, which leads to compromi

55 ce of embolism in the leaves and the stem by several days.

56 Additional illnesses were identified within several days.

57 Progesterone (P4) has been used for several decades in endometrial cancer treatment, especia

58 Over the past several decades, BP has declined and hypertension contro

59 lthough their production has been banned for several decades.

60 CB approach partially restored expression of several derepressed miR-155 targets in tumor-infiltratin

61 We identified several different aggregating sites from limited proteol

62 MMB target genes are overexpressed in several different cancer types and their elevated expres

63 nd neurotoxin strychnine, are synthesized in several different cellular locations.

64 dSe quantum dot (3.0 +/- 0.2 nm) can replace several different dye catalysts needed for five differen

65 how that cis P-tau induction is a feature of several different forms of TBI in humans, and that admin

66 Using several different phylogenetic methods, we analyzed vira

67 C. auris is commonly misidentified as several different yeast species by commercially availabl

68 ured in solution; however, this approach has several disadvantages that can reduce sensitivity, such

69 s, it is expected that mechanisms underlying several disease states involving the interactions betwee

70 ince oxidative stress and Nrf2 are linked to several diseases, cell competition may occur in a number

71 licing (AS) events have been associated with several disorders.

72 Several distinctive features observed in ISAV HE are not

73 ables, connection to extensive annotation of several domain-relevant semantic classes, and connection

74 tic analysis revealed significant changes in several dynamic and static gait parameters resulting in

75 t the spawning phenology and distribution of several ecologically and commercially important fish spe

76 y, IFI outbreak investigations have revealed several emerging issues, including new populations at ri

77 Secondly, several emulsions based on plant oils differing in their

78 me profiling (rRibo-seq) data and outperform several established methods in both computational effici

79 ncreased number of population geneticists in several European countries).

80 We show several examples of using this cartridge to perform rapi

81 of nanoparticle-based drug delivery, opening several exciting avenues for selective and prolonged car

82 The Vd991 genome harbored several exclusive, lineage-specific (LS) genes within LS

83 Also STELLS2 is usually more accurate than several existing methods when there is one allele per sp

84 Several extracts of examined Rosa species demonstrated i

85 n of AGO4-dependent het-siRNAs also requires several factors known to participate in the effector por

86 ans regulators of EIF2B5 splicing identified several factors that influence intron retention in EIF2B

87 Although several families with KS have been described previously,

88 (WNV) nonstructural (NS) 4B-P38G mutant has several features for an ideal vaccine candidate, includi

89 The tetramers share several features with structures reported for IAPP fibri

90 unction of TCR complexes are orchestrated by several fine-tuned cellular processes that encompass (a)

91 directly enhance microtubule growth rate by several-fold in vitro.

92 rotein has also been implicated in mediating several forms of use-dependent plasticity, but the mecha

93 We find that several fossilizable aspects of bone microstructure, inc

94 reased amounts of total cellular protein and several free amino acids.

95 he main objective of this study was to build several full-scale biosand filters (BSFs) and assess the

96 studies revealed the presence of disorder in several functional native enzymes.

97 nd its cleavage products C3a and C3b mediate several functions in the context of inflammation, but li

98 netics and molecular dynamics simulations on several GalNAc-T2 flexible linker constructs show altere

99 e introduce this dynamic utility function to several games.

100 ocompatibility Complex (MHC) region contains several gene families characterized by highly polymorphi

101 We identified several genes involved in disease resistance and pathoge

102 Due to the sequence similarity of several genes on the megaplasmid, BTA121 can serve as a

103 se-causing mutations have been discovered in several genes.

104 d beta-cell gene signatures and substantiate several genes/pathways.

105 m cell transplantation (HSCT) approaches for several genetic diseases that can be diagnosed at birth.

106 with visual and acoustic posturing found in several, geographically widespread populations of Austra

107 Over the last few years, several groups have evaluated the potential of microRNAs

108 Multiplexing of several guide RNAs does not increase the efficiency of m

109 lutathione (GSNO) increased the abundance of several histone acetylation marks in Arabidopsis (Arabid

110 eted agents has improved patient outcomes in several human cancers, no such advance has been achieved

111 Several human papillomavirus type 16 (HPV16) oncoprotein

112 ar mechanisms in human cells, we established several human stem cell lines: human embryonic stem cell

113 GRPr proteins are highly overexpressed in several human tumors, including prostate cancer (PCa).

114 n vivo in real time at high resolution along several hundred micrometers of the zebrafish spinal cord

115 netics on a much longer time scale of ten to several hundred nanoseconds.

116 in human cell proteomes and have identified several hundred residues with heightened reactivity that

117 We generate several hypotheses for future research.

118 issues and required for tumor eradication in several immunotherapy models.

119 rofiles of explicit proton transport through several important D-channel mutants.

120 egulating endosomal recycling and sorting of several important neuronal receptors.

121 We have characterized several important predictors of deceased donor kidney di

122 The server summarizes several in silico prediction algorithms and conservation

123 rriers of the GABRA6 rs3219151 T allele with several independent markers and predictors of suicidal b

124 The risk of any AD and several individual ADs was consistently higher among fir

125 onmyocyte transcriptional programs uncovered several injury-responsive genes across regenerative and

126 of post-natal lung development and revealed several insights, including in sphingolipid-mediated apo

127 Teamwork competency was assessed using several instruments with extensive validity evidence, in

128 hylamino-L-alanine (BMAA) has been linked to several interrelated neurodegenerative diseases.

129 These genes included several involved in bacterial envelope biogenesis, prote

130 road applications of fatty acid-conjugation, several issues should be addressed, including a poor sol

131 This simple chemical approach addresses several key challenges, such as control over phase purit

132 lts show that the combination of activity of several key kinases can predict the occurrence of long-l

133 Several key regulators of ciliogenesis and ciliary signa

134 This work regulates several key variables of PbS NC assembly (e.g., NC conce

135 Calcium orchestrates the activity of several kinases and phosphatases, which interact in a co

136 EVS activation engages several kinetically distinct synaptic processes that pro

137 g patient survival, as well as in predicting several known histopathological subtypes of breast cance

138 Several Kruppel-like transcription factors (KLF), includ

139 long-acting antiretroviral response against several laboratory-adapted and clinical HIV-1 isolates.

140 Several large-scale efforts have systematically catalogu

141 sly moving around on lakes were described by several Latin authors almost two millennia ago.

142 tion factor family are pivotal regulators of several lineage-selective differentiation programs.

143 Several lines of evidence suggest that parvalbumin (PV+)

144 les, or personnel proved to be important for several livestock epidemics.

145 the laser frequency as it is scanned across several longitudinal modes of the optical cavity.

146 There are several major mechanisms that cause AF in patients, incl

147 by time-of-flight, we were able to identify several major time-dependent phenotypic changes in blood

148 intestinal bacteria can promote infection of several mammalian enteric RNA viruses, but the mechanism

149 olecules, including the adhesion proteins of several marine organisms.

150 Several mechanisms of action have been proposed, includi

151 ys of alpha-satellite DNA, which spans up to several megabases.

152 an influence cellular inflammatory responses.Several metabolic factors affect cellular glucose metabo

153 of MeCP2 suggests that it may be involved in several metabolic pathways, but the molecular mechanisms

154 Cancer cells share several metabolic traits, including aerobic production o

155 Several metalloindene complexes have been isolated and c

156 RATIONALE: There are several methods to measure cardiomyocyte and muscle cont

157 This drift over several micrometers is reversible and can be controlled.

158 Although several microRNAs were predicted to bind CircPVT1, only

159 informatics approach, the authors identified several miR-7a2 target genes and pathways that have not

160 or MjAgo function, we analysed the effect of several MjAgo mutants.

161 Several models have been proposed to describe body sway

162 On the contrary, 1F11 showed efficacy in several models of inflammation yet was less potent at in

163 SSB homotetramers bind ssDNA in several modes that differ in occluded site size and coop

164 onships on our original series by presenting several modifications in the lead compounds 1 (HS665) an

165 Today, several modifiers have now been studied in enough detail

166 nd recent fracture (all markers increase for several months).

167 We previously reported that several mosquito species, including Aedes aegypti, do no

168 Several motif variant peptides translocate into syntheti

169 Several mouse models have been generated to study OPMD;

170 rns under severe OXPHOS deficiency comparing several mouse models, that will deepen our understanding

171 g and demethylation activity that influences several mRNA processing events.

172 ed by mass spectrometry analysis showed that several N-terminally truncated amyloid-beta42 species, r

173 ural products was designed, aiming to access several natural products from a common synthetic interme

174 The aqueous bulk diffusivities of several near-spherical (icosahedral) and nonspherical (t

175 In recent years, several network models have been introduced to elucidate

176 n deformation and damage are associated with several neurodegenerative conditions.

177 ntion because of its possible implication in several neurological and psychiatric disorders, includin

178 However, this technology has also raised several new computational challenges.

179 nt evolution of these structures, we observe several new features.

180 nse to a need for better sepsis diagnostics, several new gene expression classifiers have been recent

181 In this Series paper, we explore several new ideas that could improve understanding of th

182 Several new pairs were applied in a multimolecular FRET

183 sed transcriptional profiling and identified several novel candidate retinotectal guidance molecules.

184 Here, we identify several novel CO2-dependent changes in the NF-kappaB pat

185 netics of primary brain tumors by uncovering several novel driver genetic alterations.

186 These studies have raised several novel insights on transcriptional regulation suc

187 ression in many precerebellar neurons and in several nuclei implicated in the control of autonomic fu

188 imate intakes of energy, macronutrients, and several nutrients in fruits and vegetables, such as caro

189 his thesis was put forward after discounting several O2 production mechanisms in comets, including ph

190 The beneficial effects of several of the antimalarial drugs (AMDs) on clinical fea

191 ent state and during PSC-differentiation for several of the CBX3 subfragments.

192 tently inserted images of the wrong blots in several of the figures, resulting in the duplications; h

193 ungi have been reported from many plants and several of these fungi have been shown to contain viruse

194 Several of these mutations result in MEK1 constitutive a

195 Several of these processes may be potential therapeutic

196 Several of these proteins showed high diagnostic values

197 r a large diversity of coronaviruses (CoVs), several of which are related to zoonotic pathogens that

198 hogen that lead to metal homeostasis provide several opportunities for interception and, thus, allow

199 that a thin metasurface coating can control several optical properties simultaneously over a broad f

200 s(-1) mum(-2) ) in a natural scene vary over several orders of magnitude from shady woods to direct s

201 A) were synthesized with stability constants several orders of magnitude higher than those of gadolin

202 prisingly, the resulting current changes are several orders of magnitude larger than that expected fr

203 e to accelerate surface reaction kinetics by several orders of magnitude.

204 y affected, but Ebola cases were exported to several other African and European countries as well as

205 Also, several other components of IL6 signaling were affected,

206 d Drug Administration (FDA) in late 2016 and several other compounds are in advanced clinical trials.

207 Variants in several other genes encoding members of the TRAPP comple

208 ogically, the AR pathway has cross-talk with several other key signaling pathways, including the PI3K

209 of lytic viral expression but do not inhibit several other lytic activation pathways.

210 f PhosphoPredict is competitive with that of several other popular prediction tools, including Kinase

211 own significantly with the identification of several other reflexes regulating discrete immune functi

212 og, associates with all 13 eIF3 subunits and several other translational preinitiation factors.

213 and lymphoproliferative diseases, as well as several other types of cancer.

214 We further uncover that several P2X receptors, including those able to desensiti

215 he case of the three- and four-stage models, several parameters that are theoretically structurally i

216 d method used to protect individuals against several pathogens and toxins.

217 y and cohesion of the blood-brain barrier in several pathophysiological states.

218 Among several pathways implicated in E-T coupling, activation

219 cently, our laboratory and others have shown several pathways of regulation of ILC2s by co-stimulator

220 cs, namely age, sex, and ethnicity; however, several patient-level variables could not be included in

221 Several peptides with DPP-IV inhibitory features or know

222 At baseline, several PFAS were cross-sectionally associated with smal

223 pic electrophiles has been investigated with several phenols.

224 of maternal exposure to early-life stress on several phenotypic traits in their offspring in a functi

225 Multiexcitonic transitions and emission of several photons per excitation comprise a very attractiv

226 Several phototrophic bacterial clades are thought to hav

227 Sialic acids play many important roles in several physiological and pathological processes, includ

228 ubiquitin-like (Ubl) proteins is crucial for several physiological processes and in the onset of vari

229 a mechanism which could be of relevance for several physiological processes.Proteins fold under mech

230 We highlight several plant natural products that are either in the cl

231 odomain is a conserved protein fold found in several plus-strand RNA viruses that binds to the small

232 In mammals and yeast, several PMPs traffic via the ER in a Pex3- and Pex19-dep

233 Taken together, these data highlight several potential biomarkers that can be used in a blood

234 This article reviews several potentially paradigm-changing mechanisms enabled

235 Our analysis identified several previously unknown signatures of infection, such

236 mass of compelling data that throws light on several previously unresolved issues.

237 injected at ZT2 increased the expression of several pro-inflammatory genes within the spleen; this w

238 rotein (iafgp), which encodes a protein with several properties, including the ability to alter bacte

239 N-termini of several proteases were downregulated in prt6, including

240 Several protein combinations outperformed hemoglobin in

241 Several proteins expressed at the inner leaflet of the p

242 Several proteolytic processes were clearly site-specific

243 We found however that several [PSI (+)] strains harbored an additional chromos

244 We also identify age-onset rhythmicity in several putative primary piRNA transcripts overlapping a

245 Despite their functional importance, several questions remain about how these proteins are as

246 nd BRAF induce perinuclear relocalization of several RAS pathway proteins, including the kinases CK2

247 .1-1.2 log unit for equilibrium constants of several reactions leading to halamines in water.

248 ribed previously, our case is noteworthy for several reasons.

249 Indeed, several recent challenges hosted by the U.S. government

250 Several recent papers report spectacular, and unexpected

251 ears to provide higher value for patients in several recognized high-risk subgroups.

252 ein, we address the diverse contributions of several recombination/repair proteins to telomere mainte

253 Several regional associations between gait speed and PiB

254 gy was associated with elevated perfusion in several regions including the right dorsal anterior cing

255 at light absorption by brown carbon (BrC) in several regions of the world is approximately 30-70% of

256 is controlled by the combinatorial action of several regulatory proteins.

257 analysis of the Fermi surface of lithium in several relevant structures.

258 Recently, there have been several reports describing their application to the dete

259 NAs' 3'UTRs have enriched binding motifs for several RNA-binding proteins, which implies extensive tr

260 In malaria, CD36 plays several roles, including mediating parasite sequestratio

261 However, several samples were poorly predicted suggesting that ch

262 mouse models it normalized protein levels of several SCA2-related proteins expressed in Purkinje cell

263 ) sensors at a range of time points spanning several seconds and subsequently sort a mixed-cell popul

264 Several sensitivity analyses were performed restricting

265 We report several series of pyrazolopyran-based inhibitors targeti

266 lliative needs has led to the development of several service-level interventions intended to improve

267 Unlike other macrolides, which carry several side chains, a single desosamine sugar is attach

268 Several significant associations were identified with mi

269 iew the status of these clinical efforts for several significant retinal diseases, describe the chall

270 We produced several simple models inspired by the known anatomical s

271 However, these markers are subject to several sources of variability, including feeding (resor

272 The method was able to detect several species of crab spiked into complex food matrice

273 ribution of aromatase (estrogen synthase) in several species suggest that mechanisms for neuroestroge

274 individual differences (g) in performance in several species, and also at the aggregate level (G); ho

275 In this article, we summarize several statistical approaches that can be used to test

276 Although several steps in MPO biosynthesis and processing have be

277 on is triggered by allergen exposure through several steps including release of IL-33, which promotes

278 It is known to sense several stimuli that are potentially associated with the

279 Investigation of several stress-related parameters in SeCspA and SeCspB t

280 have synthesized oligonucleotides containing several structurally and electronically varied artificia

281 Several studies have defined transcription-induced nucle

282 Recently, however, several studies have determined that genes known to have

283 Several systemic medications for low back pain are assoc

284 he treatment of advanced breast cancer, with several targeted therapies that enhance the efficacy of

285 We perform survival analysis of several TCGA subtypes and find that GRAPE pathway scores

286 unit (April 2011-April 2014) we implemented several technical modifications to reduce environmental

287 ield SWNTs with large length polydispersity (several tens of nanometers up to centimeters) and hetero

288 Based on comparisons between several theoretical and experimental datasets, we assign

289 s, and thus entanglement swapping occurs for several thousand pairs of spatial light modes simultaneo

290 alysis workflows are required to be executed several times to systematically correlate output variati

291 Several transcription factors regulating pancreas lineag

292 C-MYC expression and increased expression of several tumor suppressor genes, including Src homology r

293 ral primate retina with single-electrode and several types of multi-electrode stimulation.

294 Several ubiquitin chain types have remained unstudied, m

295 associated cancer risks and pathogenicity of several variants in the Icelandic population.

296 e to infection and the replicative cycles of several viruses.

297 ctrostatic, because an explicit inclusion of several water molecules at the density-functional theory

298 RW was defined in several ways, with the main definition being physician-d

299 ght scatter technology has been proposed for several years as a rapid screening tool, whereby negativ

300 In the past several years, inflammasome activation and subsequent si