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3 tacrolimus, Bonferroni's P<0.001) and in the severe combined immunodeficient-beige mice (117+/-18 in
6 fused W6/32 Fab'2 antibody to human HLA into severe combined immunodeficient/beige mice that had been
7 To address this we used nonobese diabetic-severe combined immunodeficient-beta(2) microglobulin kn
8 ion of ospA mRNA was found in tissues of C3H-severe combined immunodeficient (C3H-scid) mice, but not
9 Human fetal lung tissue was implanted into severe combined immunodeficient (CB17-scid) mice and ino
10 l evidence that in a recombination inducible severe combined immunodeficient cell line poly(ADP-ribos
13 s to restore euglycemia in nonobese diabetic/severe combined immunodeficient diabetic recipients was
14 the recurrence of autoimmune diabetes in NOD/severe combined immunodeficient disease (SCID) islet iso
15 al vein of either C57BL/6 (DNA-PKcs(+/+)) or severe combined immunodeficient (DNA-PKcs(-/-)) mice.
19 f immunocompetent limited flora (I-LF) mice, severe combined immunodeficient limited flora (SCID-LF)
20 antation of these cells in nonobese diabetic-severe combined immunodeficient mice (a) generated xenog
21 fts in three genetically isolated strains of severe combined immunodeficient mice (C.B-17, C57BL/6J,
22 uction of the human HGF ligand in transgenic severe combined immunodeficient mice (hHGF(tg)-SCID mice
26 mum tolerated dose of 2L-Rap-hLL1-gamma4P in severe combined immunodeficient mice (SCID) or BALB/c mi
27 ntitumor effects were markedly diminished in severe combined immunodeficient mice and (b) CD8+ T cell
30 nted tumors when transplanted into syngeneic severe combined immunodeficient mice and normal mice.
31 MDMs were injected into the basal ganglia of severe combined immunodeficient mice and then Li was adm
32 e studied the effects of THMAM-MD in vivo in severe combined immunodeficient mice bearing HT-29 colon
35 ncer and significantly prolonged survival of severe combined immunodeficient mice bearing LAPC-4 xeno
36 activity of 8H9(scFv)-PE38 was evaluated in severe combined immunodeficient mice bearing MCF-7 breas
39 PET/CT small-animal imaging was performed in severe combined immunodeficient mice bearing solid and d
41 e drug combination decreased tumor volume in severe combined immunodeficient mice by approximately 60
42 growth and the gain in mean tumor volume in severe combined immunodeficient mice compared with vehic
43 nd engraft immunodeficient nonobese diabetes/severe combined immunodeficient mice during both primary
44 cific neutralizing anti-CXCL12 antibodies to severe combined immunodeficient mice expressing human no
45 on of late-passage H-Ras-expressing cells in severe combined immunodeficient mice formed carcinomas w
46 eplication in nontumor tissues and protected severe combined immunodeficient mice from developing let
47 was used in vivo to treat nonobese diabetic/severe combined immunodeficient mice given injections of
49 he marrow space of the bone implanted in the severe combined immunodeficient mice implanted with feta
50 0530 profoundly inhibits tumor metastasis in severe combined immunodeficient mice implanted with GRP-
51 opic HIV-1(JR-CSF) isolate (JR-CSF mice) and severe combined immunodeficient mice implanted with huma
55 CDV) and octadecyloxyethyl-CVD (ODE-CDV)--in severe combined immunodeficient mice in which either hum
56 5(+) T cells to infected macrophage-depleted severe combined immunodeficient mice induced CNS demyeli
57 ionship between phospho-AKT and FAS in vivo, severe combined immunodeficient mice injected intraperit
58 meliorated adoptively transferred ileitis in severe combined immunodeficient mice injected with CD4 +
60 dies, BMSCs and ECs were cotransplanted into severe combined immunodeficient mice on biodegradable po
61 t study, we induced EAE in T-cell-deficient, severe combined immunodeficient mice or in immunocompete
63 macrophages (MDMs) into the basal ganglia of severe combined immunodeficient mice recapitulates histo
64 th a targeted deletion of the T-bet gene and severe combined immunodeficient mice receiving CD4+ cell
65 er growth was evaluated in hu-PBL-SCID mice (severe combined immunodeficient mice reconstituted with
67 uman ovarian tumor cells into the ovaries of severe combined immunodeficient mice resulted in periton
68 racranial implantation of human gliomas into severe combined immunodeficient mice showed a marked red
69 The standard adoptive transfer study in NOD-severe combined immunodeficient mice showed that periphe
71 following immunization of nonobese diabetic-severe combined immunodeficient mice that were repopulat
74 cells harvested from carcinoma formation in severe combined immunodeficient mice were designated caM
80 tin-expressing tumors grown as xenografts in severe combined immunodeficient mice were responsive to
83 ive, Fc-dependent, passive immunity, even in severe combined immunodeficient mice with an established
84 inst subcutaneous B-cell tumor xenografts in severe combined immunodeficient mice with comparable or
85 KLMS-1 and rhabdomyosarcoma RD xenografts in severe combined immunodeficient mice with DC101 resulted
86 HCV-infected urokinase plasminogen activator-severe combined immunodeficient mice with livers repopul
87 Furthermore, Kp-10 inhibits tumor growth in severe combined immunodeficient mice xenografted with hu
89 volume, rate of metastasis, and mortality of severe combined immunodeficient mice xenografted with PC
90 model originating from footpad injection in severe combined immunodeficient mice, 95% of the resulti
91 ere injected directly into the peritoneum of severe combined immunodeficient mice, and in a syngeneic
92 neither resulted in weight loss nor death in severe combined immunodeficient mice, and pock lesions w
93 the growth of TPras transgenic melanomas in severe combined immunodeficient mice, blocked invasive b
94 model established by tail vein injection in severe combined immunodeficient mice, clonality of lung
96 sgene expression was substantially higher in severe combined immunodeficient mice, indicating that in
97 as far less efficacious in immunocompromised severe combined immunodeficient mice, indicating the req
99 ally injected into the basal ganglia of CB17 severe combined immunodeficient mice, received daily int
102 When injected into the mammary fat pads of severe combined immunodeficient mice, the tumors formed
104 marrow of human bones that were implanted in severe combined immunodeficient mice, tumors formed by c
105 Finally, using an angiogenesis assay in severe combined immunodeficient mice, we demonstrate tha
106 lls, bone marrow chimeras, and reconstituted severe combined immunodeficient mice, we identify the pr
107 human stem cell-engrafted nonobese diabetic/severe combined immunodeficient mice, where 24% of the h
108 ation of SKOV3ip1 cells in nonobese diabetic/severe combined immunodeficient mice, with increased pho
149 d not express uPAR formed palpable tumors in severe combined immunodeficient mice; however, metastase
150 asion assays, and/or injected into flanks of severe combined immunodeficient mice; xenograft tumor gr
151 owth of malignant mesothelioma xenografts in severe-combined immunodeficient mice and extended host s
155 line (EGI-1) after xenotransplantation into severe-combined-immunodeficient mice, (3) expression of
156 6Mre11(ATLD1/ATLD1) and C57BL/6(Prkdc/SCID) (severe combined immunodeficient) mice exposed to low-dos
157 ation in soft agar, tumor formation in SCID (severe combined immunodeficient) mice, and adhesion.
160 an peripheral blood leukocytes (hu PBL-SCID [Severe Combined Immunodeficient] mice) to test the hypot
162 prevent progression of established CaP in a severe combined immunodeficient mouse implanted with fet
163 f normal islets in a streptozotocin-diabetic severe combined immunodeficient mouse marginal islet mas
175 one B (dEpoB) in xenograft nonobese diabetic/severe combined immunodeficient mouse models with subcut
177 ound to inhibit pancreatic tumor growth in a severe combined immunodeficient mouse xenograft model.
178 c. human GD2-positive melanoma growth in the severe combined immunodeficient mouse xenograft model.
179 These investigations in a nonobese diabetic severe combined immunodeficient mouse-human neural cell
181 dicates that the NOD/SCID (nonobese diabetic/severe combined immunodeficient) mouse model can be a va
182 ta-glucuronidase-deficient nonobese diabetic/severe combined immunodeficient/mucopolysaccharidosis ty
183 geneic graft-versus-host disease (X-GVHD) in severe combined immunodeficient murine recipients of hum
184 bet knockout (KO) mutants, or congenic SCID (severe, combined immunodeficient) mutants were given liv
185 BD islets transplanted to non-obese diabetic-severe combined immunodeficient (NOD-SCID) mice efficien
190 population with use of the nonobese diabetic/severe combined immunodeficient (NOD/SCID) and NOD/SCID
191 ngraftment of AML cells in nonobese diabetic/severe combined immunodeficient (NOD/SCID) animals, and
193 ibialis anterior muscle of nonobese diabetic-severe combined immunodeficient (NOD/SCID) beta 2m(-/-)
194 higher tumor incidence in nonobese diabetic/severe combined immunodeficient (NOD/SCID) Ilgamma2(null
196 selected for passage into nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice and mini
197 is trial transplanted into nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice resulted
198 ns in the liver and gut of nonobese diabetic-severe combined immunodeficient (NOD/SCID) mice that und
199 gate the in vivo efficacy, nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice were xen
200 ultiple ALL cell lines and nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice xenograf
201 the retroorbital plexus of nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice, allowed
202 IM CD34(+) cells engrafted nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice, demonst
203 ncreased tumorigenicity in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice, possibl
204 xenografts established in nonobese diabetic/severe combined immunodeficient (NOD/SCID) mice, were di
209 Here we report that a new nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse line ha
210 er, when injected into the nonobese diabetic/severe combined immunodeficient (NOD/SCID) mouse prostat
211 We examined whether the nonobese diabetic/severe combined immunodeficient (NOD/scid) mouse, which
213 ll as stem cells using the nonobese diabetic/severe combined immunodeficient (NOD/SCID) xenograft mod
214 e was backcrossed onto the nonobese diabetic/severe combined immunodeficient (NOD/SCID) xenotransplan
215 Stem cell engraftment into nonobese diabetic-severe combined immunodeficient (NOD/SCID)/beta2m-/- mic
216 (+) B-cell malignancies in nonobese diabetic/severe combined immunodeficient (NOD/SCID)/gamma(c)(null
217 regression was blocked in nonobese diabetic/severe combined immunodeficient (NOD/SCID-gamma) mice, w
218 e therefore developed an in vivo MM model in severe combined immunodeficient/nonobese diabetic mice i
219 rsus FasL(-/-) mouse liver CD8(+) T cells to severe combined immunodeficient or RAG1(-/-) recipient m
222 nfected donors expanded in reovirus-infected severe combined immunodeficient recipient mice and media
223 il also improved transduction in human SCID (severe combined immunodeficient) repopulating cell (SRC)
226 or its ability to protect wild-type (WT) and severe combined immunodeficient (SCID) C.B-17 mice again
227 uated envelope SU cloned sequences from five severe combined immunodeficient (SCID) foals infected wi
228 raacetic acid (DOTA)-RGD in 20 tumor-bearing severe combined immunodeficient (SCID) mice after a bolu
230 titumor effects of MEDI-575 in tumor-bearing severe combined immunodeficient (SCID) mice and in genet
231 xpressed in autoimmune target tissues of NOD/severe combined immunodeficient (scid) mice and of autoi
232 in the brain's extracellular space of C.B.17 severe combined immunodeficient (scid) mice and tumor ce
233 antibody significantly prolonged survival of severe combined immunodeficient (SCID) mice bearing CD70
234 f B-B4-DM1 in 3 human MM models in mice: (1) severe combined immunodeficient (SCID) mice bearing subc
235 e tissues (5-8), two studies have shown that severe combined immunodeficient (SCID) mice can be infec
237 iver homogenates after 24 serial passages in severe combined immunodeficient (SCID) mice caused sever
238 ted in urokinase plasminogen activator (uPA)/severe combined immunodeficient (SCID) mice engrafted wi
240 -dependent protein kinase (DNA-PK)-defective severe combined immunodeficient (SCID) mice have a great
241 be here a novel in vivo model of human WM in severe combined immunodeficient (SCID) mice implanted wi
243 splantation of purified HSCs into a panel of severe combined immunodeficient (SCID) mice leads to a r
244 and their splenocytes were transferred into severe combined immunodeficient (SCID) mice to induce IT
245 man dorsal root ganglion (DRG) xenografts in severe combined immunodeficient (SCID) mice to investiga
248 WT) mice were subjected to DNFB-induced CHS, severe combined immunodeficient (SCID) mice were injecte
249 nificantly extends survival of 697 xenograft severe combined immunodeficient (SCID) mice without disc
250 e was tested for its metastatic potential in severe combined immunodeficient (SCID) mice, by i.v. inj
251 When coinjected with human MM cells into severe combined immunodeficient (SCID) mice, green fluor
253 AML cells in vivo in nonobese diabetic (NOD)-severe combined immunodeficient (SCID) mice, suggesting
256 ith the cDNA for heparanase are implanted in severe combined immunodeficient (SCID) mice, the resulti
274 e studied hippocampal synaptic function in a severe combined immunodeficient (SCID) mouse model of HI
275 and tumor formation in an immunocompromized severe combined immunodeficient (SCID) mouse model of or
278 ntaneous metastasis assay was performed in a severe combined immunodeficient (SCID) mouse model.
279 med by human prostate cancer cell lines in a severe combined immunodeficient (SCID) mouse tibial inje
280 anti-proliferative effects in the human skin-severe combined immunodeficient (SCID) mouse transplant
281 e show that LRP-1 is abundantly expressed in severe combined immunodeficient (SCID) mouse xenografts
282 in psoriasis in an in vivo system using the severe combined immunodeficient (SCID) mouse-human skin
285 ive to adult bone marrow in allogeneic fetal severe combined immunodeficient (SCID) recipients compar
287 ymphocytes and within human thymic grafts in severe combined immunodeficient (SCID)-hu (Thy/Liv) mice
288 tivities of docetaxel both in culture and in severe combined immunodeficient (SCID)-human model of ex
289 we measure the activity of multipotent human severe combined immunodeficient (SCID)-repopulating cell
290 th pleiotrophin also substantially increased severe combined immunodeficient (SCID)-repopulating cell
291 wn in the epithelium-free mammary fat pad of severe combined immunodeficient (SCID)/Beige and nonobes
293 g plasmablasts can be enriched in vivo, in a severe combined immunodeficient (SCID)/beige mouse host.
294 (+) PMF CD34(+) cells into nonobese diabetic/severe combined immunodeficient (SCID)/IL-2Rgamma(null)
296 ed the growth of primary tumors in the human severe combined immunodeficient (SCID-hu) model of myelo
297 ibodies on an ATL model in nonobese diabetic/severe combined immunodeficient (SCID/NOD) wild-type mic
298 (PMNs) and in human intestinal xenografts in severe-combined immunodeficient (SCID-HU-INT) mice, a no
299 um antibodies to the systemic compartment of severe-combined-immunodeficient (SCID) mice temporarily
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