1 ner, mimicking the function of Dictyostelium severin.

2 l migration, the simultaneous induction of M-severin and loss of gelsolin during epithelial transform

3 ng proteins such as gelsolin, scinderin, and severin, are calcium-regulated actin-modifying proteins.

4 se lung tissue contained minute amounts of M-severin, attributed to motile cells in pulmonary connect

5                    In striking contrast to M-severin, gelsolin was highly expressed in normal lung bu

6                               Induction of M-severin in an invasive tumor was directly observed in hu

7 ebae, we have identified a mammalian form of severin in murine LL/2 carcinoma cells lacking gelsolin.

8 tochemistry with antibodies directed against severin isolated from both Dictyostelium amoebae and Lew

9                         Mammalian severin (M-severin) isolated from LL/2-derived Lewis lung carcinoma

10 lium from the same patient did not express M-severin, it may serve as a sensitive marker for detectio

11                                    Mammalian severin (M-severin) isolated from LL/2-derived Lewis lun

12 n suggests that replacement of gelsolin by M-severin may function to achieve actin filament rearrange

13                                            M-severin preferentially localized to the cleavage furrow

14 structure of the F-actin binding domain 2 of severin, the gelsolin homologue from Dictyostelium disco

15               Using an antibody specific for severin, the Mr 40,000 actin filament severing protein f