ライフサイエンスコーパス: severity

1 range, 0-34; higher scores indicate greater severity).

2 amas results in an exaggerated impression of severity).

3 dverse events were generally grade 1 or 2 in severity.

4 illness in children or with critical illness severity.

5 rder, but not cognitive dysfunction or motor severity.

6 y of suicidality independent from depression severity.

7 der than 50 years of age with a range of AMD severity.

8 graphics, mechanism, vital signs, and injury severity.

9 the role of EHF in modifying CF lung disease severity.

10 e associated (adjusted P < .05) with disease severity.

11 y and negatively, respectively, with disease severity.

12 f-report numeric rating scale (NRS) for itch severity.

13 zed by different levels of influenza illness severity.

14 eks to induce a continuum of steatohepatitis severity.

15 o S. aureus expression of clfA and infection severity.

16 r response to disturbance varied with winter severity.

17 nd severe forms of disease, progressing with severity.

18 he early control of the parasite and disease severity.

19 d disease and may lead to underestimation of severity.

20 the adverse events were mild or moderate in severity.

21 phenotype bias leading to increased disease severity.

22 ever, and food allergy and increased disease severity.

23 disease and have been associated with asthma severity.

24 when adjusted for confounders, like disease severity.

25 ent for DME may experience improvement in DR severity.

26 ed with either seizure prevalence or seizure severity.

27 ith increased serum IL-17A levels and asthma severity.

28 rticipate, irrespective of previous reaction severity.

29 n chronic disease and not just biomarkers of severity.

30 on was observed according to clinical asthma severity.

31 iological activity significantly reduced AIM severity.

32 lopment of diarrhea and colitis with varying severity.

33 cumulation in the intestine, and the disease severity.

34 de that produces sputum and mediates disease severity.

35 al cycles, or altering disease incidence and severity.

36 ay be limited to patients with lower illness severity.

37 ing for baseline characteristics and disease severity.

38 ss appears to improve psoriasis symptoms and severity.

39 prescriptions, symptom duration, and symptom severity.

40 peripheral p11 levels correlate with disease severity.

41 rs58542926 polymorphisms influenced disease severity.

42 evidence), improvement was reported in pain severity (8 of 8 fair-quality studies), function (5 of 5

43 ensity was associated with the initial STEMI severity, adverse remodeling, and long-term health outco

44 Baseline severities and features of initial DR are prognostic for

45 d to aid land managers in predicting disease severity and accordingly adjust their management decisio

46 fic symptoms, medication-free days, rhinitis severity and asthma control.

47 ganese and lead are also correlated with ASD severity and autistic traits.

48 The correlation between symptom severity and baseline mood parameters supports an associ

49 ogy can be a prognostic indicator of disease severity and can influence treatment decisions.

50 Parent-reported child depression severity and child cortisol response following stress we

51 ltivariate regression controlling for injury severity and demographic variables, the difference in LO

52 ach mating type treated mice showed that the severity and disease progress were enhanced in (+) matin

53 The correlation between disease severity and dopamine loss appears linear, but the major

54 ganisms including pathogens in asthma onset, severity and exacerbation, yet with the exception of ant

55 have caused human infections, with differing severity and frequency.

56 th CNS cryptococcosis may help gauge disease severity and guide the therapeutic approach in those pat

57 types that are indicators of risk for asthma severity and instability.

58 irect impact of antibiotic resistance in the severity and outcomes of P. aeruginosa infections is not

59 or HFpEF, similarly associating with disease severity and outcomes.

60 d that the association between adult symptom severity and prefrontal neuronal activity was confined t

61 radation, are possible biomarkers of disease severity and progression in bronchiectasis.

62 hat paediatric liver disease differs in both severity and rate of progression compared with adult for

63 sor was associated with increased depression severity and reduced amygdala reactivity to salient outc

64 IX levels are a major determinant of disease severity and risk of liver dysfunction in patients with

65 AIM: To analyze associations between severity and sensitization patterns, patient characteris

66 The interaction between baseline severity and treatment was significant (beta=0.22, 95% C

67 l cardiac chemical signatures related to the severity and ultimate outcome of the infection.

68 del of multiple sclerosis, reducing clinical severity and weight loss.

69 we found hematopoietic phenotypes of graded severity and/or stage specificity that together delineat

70 ying autism spectrum disorder social symptom severity, and further research into the gyral surface of

71 2 years; and emotional awareness, depression severity, and general health outcomes in children and ad

72 ge, prestroke functional limitations, stroke severity, and history of atrial fibrillation.

73 Advancing age, shock severity, and persistent organ dysfunction are predictiv

74 vioral symptom severity, psychiatric symptom severity, and sleep impairment were significantly worse

75 stimated bottleneck size and donor infection severity, as measured by temperature.

76 There is a lack of simple and validated severity assessments that are feasible for clinical prac

77 predicted sustained improvements in symptom severity at 3-month follow-up.

78 unctioning, psychological distress, and pain severity at 4 and 24 weeks.

79 Disease severity at baseline, surgical incisions, sutures, and c

80 x10(-7)) but not with cardiovascular disease severity at baseline.

81 men is mostly because of age but also stroke severity, atrial fibrillation, and prestroke functional

82 ation of change in classification of disease severity based on alveolar bone loss and tooth loss duri

83 ther, during NIV, the categorization of ARDS severity based on the PaO2/FiO2 Berlin criteria is usefu

84 l tolerated, with diarrhea (mild-to-moderate severity) being the most common side effect.

85 severity of symptoms reported by the parent (severity: boys, 11.1 [7.7] vs girls, 9.4 [8.1]; mean dif

86 severity of symptoms reported by the child (severity: boys, 15.1 [9.8] vs girls, 11.8 [9.2]; mean di

87 correlated with ALS disease progression and severity but not with the survival time, as did neurofil

88 dies have evaluated risk factors for dry eye severity, but few have assessed risk factors or symptom

89 lar across health and the spectrum of asthma severity, but the percentage of neutrophils expressing C

90 poxygenase correlated with increased disease severity by histological evaluation and paw swelling com

91 siometry, oedema by plethysmometry, clinical severity by scoring, joint function by grid test, myelop

92 /mast cell interactions contribute to asthma severity by transiently increasing MMP activation, airwa

93 stratified by baseline C difficile infection severity, cancer presence, age (>/=75 years vs <75 years

94 n 15% of patients with ARDS, irrespective of severity category.

95 ssion tomographies at low-risk physiological severity CFR >/=2.3 to CFR <2.0, thereby implying high-r

96 us variceal bleeding stratified by cirrhosis severity (Child A versus B/C) by means of individual tim

97 hild and parent report of symptom number and severity, cognition (Standardized Assessment of Concussi

98 but they had similar pre-treatment clinical severity compared with patients who did not have GA.

99 ly delayed disease onset and reduced disease severity compared with wild-type (Plg(+)) mice.

100 AR, including use of different diagnosis and severity criteria, lack of consistent scoring or grading

101 rovided cough duration and 369 (93%) symptom severity data.

102 es recommendations for assessment of disease severity, data collection, and endpoint definitions.

103 ke recommendations for assessment of disease severity, data collection, and updated endpoint definiti

104 It is also possible that disease severity depends on the virulence of the chlamydial inoc

105 commended for patients with mild to moderate severity depression.

106 Disease severity does not influence the response to systemic cor

107 e, baseline peanut/egg sensitization, eczema severity/duration, age of introduction, gender, and race

108 lcoholic hepatitis based on baseline disease severity, extent of therapeutic improvement, long-term i

109 Impingement severity for both ITI (p = 0.01) and BTB (p = 0.05) was

110 as a 40% or greater reduction in depression severity from baseline) averaged over months 4-6 of the

111 present at time of reaction and anaphylaxis severity grades were retrieved.

112 across epidemics since 2013, while clinical severity has not changed substantially.

113 tics, genotypes, and determinants of disease severity in a large patient cohort with EPP or XLP.

114 sorders, disorder age at onset, and disorder severity in a nationally representative sample of US ado

115 PTTG1IP and MAML3 are associated with BHR severity in adult asthma.

116 h doses of corticosteroids indicates disease severity in asthmatic patients.

117 A significantly reduced seizure duration and severity in CD rats after acute seizures with subsequent

118 nal brain activity to reward, and depression severity in children 4 to 6 years old.

119 MRI-visible perivascular space severity in either location did not predict PiB-PET.

120 cutaneous anakinra versus placebo on fatigue severity in female patients with CFS.

121 pes associated with coronary atherosclerosis severity in patients at least 65 years old.

122 possible that the z-score underestimates AL severity in patients older than 60 years of age with sev

123 rize disease progression, heterogeneity, and severity in patients with severe or difficult-to-treat a

124 ent with doxycycline does not reduce fatigue severity in QFS patients compared to placebo.

125 B signaling that is correlated with aneurysm severity in these human subjects.

126 ty was not a reliable surrogate for glaucoma severity in this cross-sectional study.

127 ular correlates of strain-dependent epilepsy severity in this model.

128 T2 genes increased with severity in those treated with corticosteroids but were

129 clinically significant reduction in fatigue severity in women with CFS and severe fatigue.

130 atment allocation, using the Eczema Area and Severity Index (EASI), which was log-transformed for ana

131 inical measures included the Ichthyosis Area Severity Index (IASI), which integrates erythema (IASI-E

132 analysis showed that intrahospital Pneumonia Severity Index (PSI) class (hazard ratio [HR], 2.45, P =

133 The current disease severity index may have relevance for clinical practice,

134 notype also had the highest Composite Asthma Severity Index score, the highest asthma treatment step,

135 nline ratings of insomnia severity (Insomnia Severity Index) and online sleep diary-derived values fo

136 with trabectome surgery using a new glaucoma severity index.

137 ere self-reported online ratings of insomnia severity (Insomnia Severity Index) and online sleep diar

138 ened impact of combined etiologies on anemia severity is highlighted.

139 lial nitric oxide (NO) pathways with disease severity is unknown.

140 m accurately discriminated stages of disease severity (low to high): A (5-6 points), B (7-9), and C (

141 is associated with indices of global illness severity, markers of end-organ dysfunction, and profiles

142 ease in DTN time, 95% CI 1%-20%), and stroke severity (National Institutes of Health Stroke Scale sco

143 To balance injury severity, nonrecipients of prehospital transfusion were

144 ealing was defined as CD Endoscopic Index of Severity of 0 in CD or Mayo endoscopic sub-score of 0-1

145 The incidence and severity of 15 gastrointestinal symptoms and overall sym

146 ilar between vehicle and CAR-DCN groups, the severity of AAA in the CAR-DCN group was significantly r

147 AAL(S) reduced the severity of acute AAD by suppressing tissue eosinophils

148 ake Louise Questionnaire Score to assess the severity of acute mountain sickness.

149 Incidence and severity of adverse events was mostly similar between gr

150 isotype resulted in reduced development and severity of anaphylaxis as measured by decline of body t

151 anxiety occurred in all groups; however, the severity of anxiety and social anxiety symptoms varied b

152 n chondrocytes also modulates the course and severity of arthritis.

153 ate PVR at 30 days showed a reduction in PVR severity of at least 1 PVR class at 1 year.

154 ejection, and attenuates the progression and severity of autoimmune diseases and experimental colitis

155 leaching in 1998 and 2002 did not lessen the severity of bleaching in 2016.

156 on with propofol significantly increases the severity of bloodstream MRSA infection, even when admini

157 on and end-systolic volume, but not with the severity of brain or bone abnormalities.

158 ting that climate may moderate the forms and severity of bullying, as well as predict its prevalence

159 f patients, such as gender, impulsivity, and severity of cannabis use, when selecting a medication in

160 The type and severity of cardiac events in this population and the im

161 rise can rapidly increase the frequency and severity of coastal flooding.

162 As), and attenuated the wasting syndrome and severity of colitis ( approximately 70% reduction in the

163 Oral administration of ERG240 reduces the severity of collagen-induced arthritis in mice and cresc

164 reliminary findings of reduced incidence and severity of complications as compared with the open appr

165 mal stress precludes assessing physiological severity of coronary artery disease.

166 w reserve (FFR), an index of the hemodynamic severity of coronary stenoses, is derived from invasive

167 e ratio (iFR) is an index used to assess the severity of coronary-artery stenosis.

168 Neuropathological severity of CTE was distributed across the highest level

169 The impact of this strategy on severity of disease among infected infants has not been

170 ll-powered studies to explore differences in severity of disease and clinical outcomes are lacking.

171 low health literacy and numeracy, and higher severity of disease were independently associated with c

172 telescreening to determine the presence and severity of DR.

173 overexpression of miR-31-3p ameliorated the severity of DSS-induced colitis.

174 An important mechanism for the severity of EBOV infection is its suppression of innate

175 lationship was found between depth, risk and severity of embolism, which has not been previously demo

176 the three mental illnesses studied, and the severity of flooding might be the reason for some, but n

177 The alarming increase in the incidence and severity of food allergies has coincided with lifestyle

178 Thus, the severity of glass-ceramic degradation depends not only o

179 reased in intensity with the progression and severity of GN in rats, mice and humans.

180 heir GINS1 genotype, and correlated with the severity of growth retardation and the in vitro cellular

181 of circulating PCs and the pathogenesis and severity of HF and their impact on incident HF events.

182 hanges in the dentate gyrus translate to the severity of hippocampal sclerosis and seizure burden in

183 RYGB, high oxalate intake contributed to the severity of hyperoxaluria.

184 ffect varied, however, depending on baseline severity of hypoxemia (P = 0.0003), with harm increasing

185 kers may not only prove useful in predicting severity of illness but also will hopefully allow for id

186 ed medical ICU; p = 0.002), and had a higher severity of illness by relative expected mortality (21.3

187 tween 1997 and 2013 despite little change in severity of illness during this time.

188 d that is not readily explained by increased severity of illness.

189 e PML-IRIS stage overlap but differ in their severity of inflammation.

190 bolite profiles and brain injury topography, severity of injury, and prematurity-related clinical com

191 ss of pre-mortem clinical findings including severity of IOP elevation, retinal nerve fiber layer thi

192 burns were significantly associated with the severity of lifetime BCC.

193 s by mechanism of injury, prehospital shock, severity of limb amputation, head injury, and torso hemo

194 The coprimary outcomes were improvement in severity of liver disease (change in MELD) at 3 months a

195 Both the severity of liver disease and POPH (as assessed by MELD

196 The GSG-index is a possible marker of severity of liver disease independent of body mass index

197 eatly influence the relationship between the severity of lung injury and the degree of hypoxemia and/

198 on-affective psychosis, which are markers of severity of mental illness, and older age, which is a ma

199 propriate inflammation increase the risk and severity of mood disorders; however, only recently have

200 to disease, as inhibiting OXPHOS reduces the severity of murine colitis and psoriasis.

201 the established PCA-tdTHz, we evaluated the severity of myelin deficit lesions in rhesus monkey brai

202 -FLT PET may be a useful tool to measure the severity of myelofibrosis, and to monitor noninvasively

203 like syndrome, aprepitant did not reduce the severity of nausea when reduction in VAS score was used

204 DTI-MRN correlated closely with the severity of neuropathy, demonstrating strong association

205 ce findings were related to the presence and severity of neuropathy.

206 and dynamic retinal vascular caliber and the severity of obstructive sleep apnea (OSA).

207 atment effects were observed for duration or severity of other acute lower respiratory tract infectio

208 in mitochondrial myopathy correlate with the severity of OXPHOS dysfunction, as indicated by the leve

209 ical therapies for the ability to reduce the severity of paralysis in a mouse model of EV-D68 infecti

210 the CRR of 1:1 was inadequate to assess the severity of periodontitis on the basis of the 2D RL and

211 kine interleukin (IL)-12 correlates with the severity of periodontitis.

212 lobal pulmonary vascular remodeling, but the severity of PH correlates most strongly with venous and

213 ascularised tissue reduces the frequency and severity of pharyngocutaneous fistula formation.

214 esis to explain how this element reduced the severity of plant diseases.

215 hnicity, marital status, social deprivation, severity of psychopathology, duration of index CRT episo

216 the pace of dose increase, or the number or severity of reactions experienced.

217 ve index that correlates accurately with the severity of rejection.

218 uteroplacental insufficiency (UPI) increases severity of retinopathy of prematurity, we developed a c

219 portunity to divide patients into cohorts by severity of rod and cone dysfunction.

220 rd-mesenchymal stem/stromal cells reduce the severity of rodent E. coli-induced acute respiratory dis

221 control oxidative stress and the phenotypic severity of SCD.

222 a power, they also correlated with increased severity of sensory and executive dysfunctions (i.e. hyp

223 Chronic Health Evaluation (APACHE) II score, severity of sepsis and renal function were enrolled.

224 Exogenous IL-15 exacerbates the severity of sepsis by activating NK cells and facilitati

225 of genes that correlate negatively with the severity of SSc skin disease.

226 ies (RPs) per day, participants reported the severity of stress and craving and whether they had seen

227 nctional connectivity may be associated with severity of suicidal ideation and attempt lethality.

228 on in MDD were inversely proportional to the severity of suicidality independent from depression seve

229 Patients assessed severity of swelling using a visual analog scale seriall

230 of reduction in DNA-binding affinity and the severity of symptoms in XP patients.

231 d a small effect on the mean (SD) number and severity of symptoms reported by the child (severity: bo

232 2]; effect size, 0.35), mean (SD) number and severity of symptoms reported by the parent (severity: b

233 t of anemias at older age depends on (1) the severity of the anemia, (2) underlying condition(s), and

234 ividual patient's risk of thrombosis and the severity of the bleeding.

235 The functional severity of the CLCNKB mutation is an important determin

236 zed in this study to determine the degree of severity of the disease within an asthma cohort.

237 topic dermatitis and can result in increased severity of the disease.

238 atory cell infiltrates, independently of the severity of the exocrine lesion and in the absence of am

239 gher scores on the measures indicate greater severity of the symptoms.

240 The severity of the various ischemic fundus and retinal lesi

241 seases receiving nonpreferred therapy due to severity of their reported allergy.

242 this area correlates with the frequency and severity of violations of the Generalized Axiom of Revea

243 We examined the effects of fire severity on the soil respiration rate (Rs) and its compo

244 identified between mutation type and disease severity or progression.

245 se exposures failed to reduce the incidence, severity, or duration of AKI after cardiac surgery in hi

246 ns between the microbiota profiles and these severity outcomes (all P>/=.10).

247 ckout (FKO) demonstrates enhanced phenotypic severity over males (MKOs), due to partial redundancy wi

248 l phase, and C4 was lowest after the maximum severity peak.

249 2.0, thereby implying high-risk quantitative severity potentially appropriate for interventions but b

250 nitude of LDX-induced improvement in symptom severity predicted both direction and magnitude of LDX-i

251 el of accuracy for classification as well as severity prediction far exceeds any other approach in th

252 Sensitivity analyses stratified by TBI severity produced similar results.

253 ne expression networks in relation to asthma severity provided potentially new insight into biologica

254 isfaction with life, neurobehavioral symptom severity, psychiatric symptom severity, and sleep impair

255 ase (r = -0.451, P = 0.004), whereas symptom severity (r = 0.326; P = 0.037) and quality of life (r =

256 a hereditary neurodegenerative disease with severity ranging from progressive infantile paralysis an

257 detection of periodontal disease and/or its severity, salivary levels of NLRP3, ASC, and IL-1beta ma

258 wed a positive correlation with the Glaucoma Severity Score (rs = 0.33; P < .001) and a negative corr

259 unt trauma patients (n = 472, average injury severity score [ISS] = 20.2) exhibited elevations in pla

260 tomical injury defined as minor by an injury severity score between 2 and 8 and normal physiology as

261 e and the Clinical Global Impression Disease Severity Score but not sex (multivariate HR 0.93; 95% CI

262 of 0.24 (95% CI, 0.11-0.36) and for the MetS severity score of 0.50 (95% CI, -0.05 to 0.99).

263 and/or Abbreviated Injury Scale head-region severity score of 3 or greater) and a prehospital systol

264 tion of Diseases, Ninth Revision head region severity score of 3 or greater, and/or Abbreviated Injur

265 etransplant magnetic resonance imaging (MRI) severity score of less than 10 (scale range, 0-34; highe

266 A severity score was assigned to each patient based on the

267 re and a significant increasing trend in the severity score was observed from healthy control, to unc

268 ity, such as the Confusion Assessment Method-Severity Score, can aid in monitoring response to treatm

269 a secondary infection showed higher disease severity scores and higher mortality up to 1 year than t

270 PATIENTS OR Trauma patients with injury severity scores greater than 20 (n = 10) at days 1, 3, a

271 1(+/+) mice were challenged for CIA and mean severity scores were recorded thrice weekly.

272 c R-loops, inversely correlates with disease severity scores.

273 se some of the best single correlations with severity (Scoring of AD, or SCORAD) are detected not onl

274 ne and follow-up, patient-reported global AD severity significantly correlated with oSCORAD (Spearman

275 Dystonic symptom severity significantly correlated with theta but not bet

276 Four to five intermediate-severity stenoses were generated in the left anterior de

277 In severity-stratified analysis of PG eyes, OCT had signifi

278 clinical cutoff on the FCR Inventory (FCRI) severity subscale at screening.

279 Measures of severity, such as the Confusion Assessment Method-Severi

280 developmental windows increases ASD risk and severity, supporting the hypothesis of systemic elementa

281 ment resulted in greater improvement in PTSD severity than group treatment.

282 which uses 4 escalating tiers of hierarchal severity to derive a total score for events encountered

283 al hazards models adjusted for age, sex, AMD severity, VA, history of cataract surgery, and assigned

284 The time to maximum symptom severity varied from 1 day to more than 3 months.

285 Kidney disease severity varies considerably and accurate information re

286 Mean symptom severity was 1.99 points in the prednisolone group and 2

287 Longitudinal increase in NMS severity was associated with the older age (0.008) and l

288 Alcohol withdrawal syndrome severity was defined by CIWA-Ar score as minimal (< 10),

289 y was performed, and intestinal inflammation severity was evaluated histologically.

290 Coronary artery disease (CAD) severity was quantified in each subject via coronary ang

291 PPB severity was quantitated by the elevation in depressed m

292 Primary outcome (eczema severity) was assessed at baseline, 2, 4, and 6 mo, by n

293 st common adverse events of grade 3 or worse severity were anaemia (38 [19%] of 195 patients in the o

294 Both anxiety diagnosis and symptom severity were associated with smaller right hippocampal

295 fic CTSD(f/f)/p48(Cre/+) animals, markers of severity were reduced only at 1 h, whereas in the comple

296 d with RSV representing extremes of clinical severity were studied.

297 Lbh knockout exacerbated disease severity, which is associated with elevated levels of IL

298 leeding score, plaque score, and periodontal severity with linear and ordinal logistic regression mod

299 tory epithelium, causing disease of variable severity with little or no direct systemic effects.

300 ir analysis of patients with similar disease severity with or without transplantation.