ライフサイエンスコーパス: sex

1 ng and exhibiting greater V k* in the second sex.

2 ial Differences in Stroke study (REGARDS) by sex.

3 th hypertension in young adults depending on sex.

4 utionalized division of labor beyond age and sex.

5 or the whole sample as well as stratified by sex.

6 person-years were calculated by country and sex.

7 e regression to control for age at death and sex.

8 epositions due to recent unprotected vaginal sex.

9 from treatment, number of calcifications, or sex.

10 urden, presence of extrahepatic disease, and sex.

11 ted with calcified carotid plaques in either sex.

12 ng in a partial temporal segregation between sexes.

13 to oxidative stress is lost with age in both sexes.

14 perience has on this process in mice of both sexes.

15 es that differ from the soma and between the sexes.

16 of conviction for a violent offense in both sexes.

17 ts with HF (limits for mean age=49-80 years, sex=0%-92% females, left ventricular ejection fraction=2

18 well as replicated in meta-analysis of both sexes (1-tailed P = 0.021).

19 a who consented, 286 (mean age, 7.7 yr; male sex, 65.8%) were mite sensitized, and 284 were randomize

20 Natural reinforcers, like food and sex, activate this pathway, thereby increasing the likel

21 Our analyses accounted for age, sex, adiposity, and the use of psychoactive medications.

22 timate between observed BMI and AF (age- and sex-adjusted hazard ratio 1.05 [1.04-1.06] per kg/m(2),

23 The age-/sex-adjusted population attributable risk for these Simp

24 ith the MESA cohort, the race/ethnicity- and sex-adjusted risk of AMD in LSOCA was 1.75 (95% CI 1.16,

25 We determined the age- and sex-adjusted risk of death for each type of synucleinopa

26 for 19 geographical areas or ethnicities by sex, age group, and cancer type.

27 did not differ significantly with respect to sex, age, and cutaneous, abdominal, articular, or renal

28 d models, which controlled for fiber intake, sex, age, body mass index, and repeated sampling within

29 Sex, age, ethnicity, marital status, social deprivation,

30 ierarchy of regulation among multiple inputs-sex, age, nutritional status, and microbial environment-

31 ome relationship, adjusting for demographic (sex, age, race, ethnicity), socioeconomic (income, educa

32 roportional hazards models adjusted for age, sex, AMD severity, VA, history of cataract surgery, and

33 Male sex and age were also associated with appropriate ICD sh

34 ores using linear mixed models, adjusted for sex and education, and meta-analytic techniques.

35 to acute stress is known to be influenced by sex and genetics.

36 in changes on gait speed in addition to age, sex and hypertension independent from brain atrophy.

37 ye diameters and brain region volumes across sex and life stage, the latter through micro-computed X-

38 system consisted of clinical variables (male sex and previous percutaneous coronary intervention) and

39 gle equation worked well across subgroups of sex and race/ethnicity.

40 d to the odour of a non-relative of the same sex and reproductive status.

41 andard deviations below the mean for age and sex and results in moderate to severe mental deficiencie

42 ears of family formation, including opposite-sex and same-sex couples, measured brain response to cop

43 cles of capecitabine, with stratification by sex and use in adjuvant or neoadjuvant vs palliative set

44 tries divided into 21 world regions, in both sexes and 20 age groups, between 1990 and 2015.

45 yzed alphaII spectrin-deficient mice of both sexes and found that loss of alphaII spectrin causes pro

46 actors for recurrence were older age, female sex, and comorbidity.

47 dmission rates were calculated by year, age, sex, and county of residence.

48 Personal data regarding age, sex, and duration and daily frequency of smoking were ga

49 mber of patient characteristics, namely age, sex, and ethnicity; however, several patient-level varia

50 A number of factors, including age, sex, and genotype, may affect these metabolic processes.

51 tal femur and proximal tibia related to age, sex, and height.

52 ion of poor outcome were independent of age, sex, and initial rhythm but higher for out-of-hospital c

53 ciated with nonwhite race, younger age, male sex, and lack of access to health care.

54 impact, disaggregated where possible by age, sex, and location.

55 e (70% male) and 92 controls of similar age, sex, and low Framingham 10-year coronary artery disease

56 On the basis of age, sex, and MMSE score only, the 3-year progression risk to

57 Controls were individually matched for age, sex, and municipality.

58 depending on comorbid conditions, genetics, sex, and other factors.

59 tum stress, gestational age at birth, infant sex, and postnatal age at magnetic resonance imaging sca

60 , 1.28; 95% CI, 1.13-1.46) adjusted for age, sex, and race.

61 s) over the study period, stratified by age, sex, and race.A 1-y MMC in 2015 would increase the avera

62 alculated for each TFA and their sum by age, sex, and race/ethnicity (non-Hispanic white, non-Hispani

63 (HC, n = 168) was composed according to age, sex, and smoking habits.

64 CI, 1.06-2.30; P = 0.024), adjusted for age, sex, and statistically significant covariates.

65 We used logistic regression adjusted by age, sex, and study design features and examined effect modif

66 rease in global cognition, adjusted for age, sex, and study subcohort.

67 transcription of IL-1beta was higher in both sexes, and TNFalpha was elevated in females.

68 ve study, data were collected including age, sex, antiplatelet factor 4/heparin enzyme-linked immunos

69 The inclusion of sex as a biological variable in research is absolutely e

70 Future research needs to employ sex as a classification variable, as sex differences can

71 o found that Atoh1 heterozygous mice of both sexes (Atoh1(lacZ/+)) have adult-onset deafness.

72 issues then were used to predict how various sex-based differences underlie arrhythmia risk in the se

73 n-lethal prediction of ovary development and sex because only a small amount of ovary sample (<50 mg)

74 n in men, but the mechanisms underlying this sex bias are unknown.

75 Furthermore, a sex bias for severe sequelae from coxsackievirus infecti

76 putative genetic mechanisms underlying this sex bias: sex-specific heterogeneity and higher burden o

77 systems are implicated in diverse domains of sex-biased behavior and pathology, but we lack a basic u

78 oof of principle that when CRF is in excess, sex-biased CRF1 coupling translates into divergent cell

79 es in male and female brains, as a result of sex-biased CRF1 signaling.

80 That sex-biased exposure might translate to sex-specific adve

81 m manipulation disproportionately influences sex-biased gene expression but show that the direction o

82 males and persistent in females-regulate the sex-biased, STAT5-dependent expression of hundreds of ge

83 gnificant mechanistic implications regarding sex biases in NDDs.

84 We test the hypothesis that sex-biases in infection are related to variation in mult

85 ers had not smoked after correction for age, sex, birth weight, height, body weight, Tanner stage of

86 unplanned readmissions included age, female sex, black/Hispanic race, prior amputation, Charlson com

87 ios (HRs) with adjustments for baseline age, sex, body mass index, physical activity, symptoms, and r

88 l hazards models that were adjusted for age, sex, body mass index, smoking status, education, energy

89 onmental complexity affects the evolution of sex by adapting replicate populations to various environ

90 d deviations from the median BMI for age and sex), cardiometabolic outcomes, quality of life, other h

91 P values were adjusted for age, sex, carotid artery site, and family relations.

92 igh body-mass index (BMI), according to age, sex, cause, and BMI in 195 countries between 1990 and 20

93 the union of two sperm from pollen with two sex cells in the female embryo sac.

94 ur results demonstrate that the direction of sex change is a pivotal variable in predicting demograph

95 bserved that, regardless of the direction of sex change, individuals conform to the same overall stra

96 icting demographic changes and resilience in sex-changing fish, many of which sustain highly valued a

97 ad differentiation, development of secondary sex characteristics (SSC) and gametogenesis.

98 that accompany interwoven variations in sex, sex chromosome complement, and brain size.SIGNIFICANCE S

99 requires zygotic gene expression to read the sex chromosome karyotype, early embryos must remain gend

100 Sex chromosome trisomy affects 0.1% of the human populat

101 phic within species, suggesting that nascent sex chromosomes arise frequently over the course of evol

102 Sex chromosomes often differ between closely related spe

103 The house fly has sex chromosomes that resemble the ancestral fly karyotyp

104 of complex interactions among sex hormones, sex chromosomes, and immune response genes.

105 Sex-chromosomes have formed repeatedly across Diptera fr

106 nant of orangutan movement among all age and sex classes, with orangutans more likely to move in dire

107 e in the maintenance of these disorders (ie, sex, co-morbid conditions, types of trauma exposure, and

108 After adjustment for age, sex, country, and SCD phenotype, a low hemoglobin level

109 y formation, including opposite-sex and same-sex couples, measured brain response to coparental stimu

110 t failure incidence (standardised by age and sex) decreased, similarly for men and women, by 7% (from

111 susceptibility for developing diabetes in a sex-dependent manner.

112 Sex-dependent pituitary growth hormone (GH) secretory pr

113 hat E2 signaling in BLA neurons is regulated sex-dependently, presumably via mechanisms that have bee

114 modulates synaptic plasticity in rodent BLA sex-dependently.

115 The study of temperature-dependent sex determination (TSD) in vertebrates has attracted maj

116 elopment, Rspo1 is a key factor required for sex determination and differentiation of the follicular

117 nvestigate the impact of fatty acids (FA) on sex determination and reproductive development, we exami

118 sults provide crucial evidence for genotypic sex determination facilitating land-water transitions in

119 Since sex determination in C. elegans requires zygotic gene ex

120 Consequently, sex determination of juvenile remains is rarely undertak

121 onment interactions that support a polygenic sex determination system in domesticated (laboratory) ze

122 all crocodilians, has temperature-dependent sex determination, in which the sex of an embryo is dete

123 To identify regulatory sites during sex determination, we subjected Sertoli cells from mouse

124 ng model for studying this enigmatic mode of sex determination.

125 iggered a revolution in our understanding of sex determination.

126 Here, we focus on the conserved sex-determination gene doublesex (dsx) and the mechanism

127 temperature-sensitive point mutation in the sex-determination gene, transformer-2 (tra-2), using CRI

128 ing linkage mapping, polyploid phylogeny and sex-determining region (SDR) in a unified framework, we

129 hIFN-kappa) near the type I IFN locus on the sex-determining Z chromosome.

130 nce does not consistently favor the proposed sex difference in attractiveness preferences, nor the fi

131 Sex difference in mouse metabolic response to erythropoi

132 employ sex as a classification variable, as sex differences can generally be expected.

133 Traditionally, sex differences have been attributed to the differential

134 odents, and discuss the relationship between sex differences in behavior and sexual dimorphism in the

135 lence of ASD might partially be explained by sex differences in clinical symptoms, etiological models

136 hundreds of genes in mouse liver, imparting sex differences in hepatic drug/lipid metabolism and dis

137 We also found no sex differences in heroin self-administration or the str

138 and ryanodine receptors that contributes to sex differences in hyperalgesic priming.SIGNIFICANCE STA

139 Sex differences in immune responses, especially during a

140 This variation may be linked to sex differences in inflammation.

141 Accordingly, this study aimed to investigate sex differences in LV mechanics with altered adrenergic

142 d focus on understanding the determinants of sex differences in rehospitalization risk among conditio

143 We compared sex differences in rehospitalization using a Cox proport

144 state cancer but also likely contributing to sex differences in the health and diseases of man.

145 gy, but we lack a basic understanding of how sex differences in the human cerebellum are distributed

146 These sex differences in the role of these prostanoids in the

147 Whether sex differences in treatment decisions reflect patient p

148 The biological basis of these sex differences is poorly understood.

149 Regional sex differences suggest that extrinsic factors, such as

150 risk and characteristics, which accounts for sex differences, but there is also evidence to support u

151 a brain region not normally associated with sex differences, this work sheds light on ways that gene

152 ed on one sex, or include limited aspects of sex differences.

153 c expression, preceding the onset of gonadal sex differentiation.

154 ng FLG expression, FLG genetic variants, and sex, discrimination between children who will and will n

155 The presence of sex disparity in living donor kidney transplantation (LD

156 ue, we studied 87 human participants of both sexes during a stimulus-selective stop-signal task and p

157 female partners of HIV-infected men resuming sex early after male circumcision.

158 ct coverage was equitably distributed across sex, education, income, religion, and caste.

159 Analyses were performed to adjust for age, sex, educational level, history of skin cancer, and hist

160 Healthy subjects of both sexes encoded and retrieved novel objects during periods

161 in a foraging ecology, such as cooperation, sex equality and egalitarianism.

162 tion in paired kidney exchanges may increase sex equity in LDKT.

163 ST2 = .62; P = .001), less discomfort during sex (EST1 = .49 and EST2 = .66; P = .001), and less sexu

164 intensity statin prescriptions included male sex, filling beta-blocker and antiplatelet agent prescri

165 iginator attributes, specifically biological sex, from a single analyte.

166 dy quantifies the respective effects of age, sex, genetics, and cellular heterogeneity on the interin

167 ymptoms adjusted for infant characteristics (sex, gestational age, birthweight, parity and breast fee

168 gh 2013, disaggregated by condition, age and sex group, and type of care.

169 and their importance among specific age and sex groups are still poorly understood.

170 in their prodromal period across all age and sex groups, with HRs consistently increasing with proxim

171 Sex had a small effect on the mean (SD) number and sever

172 U was negatively associated with age, female sex, height, and body mass index, and these variables ac

173 re reviewed with regard to age at diagnosis, sex, histologic subtype, and other tumors presented by t

174 ical and disease processes sensitive to male sex hormone actions, thereby not only affecting the path

175 ne, dehydroepiandrosterone sulfate (DHEAS)], sex hormone binding globulin (SHBG), and EOC risk by tum

176 studied predominantly within the context of sex hormone effects.

177 s in transgender populations receiving cross-sex hormone therapy (CSHT) limits appropriate primary an

178 NK in lung cancer and may explain why female sex hormones accelerate lung cancer development.

179 are prone to vitamin D deficiency, deviated sex hormones and blood lipids.

180 e is evidence implicating the role of female sex hormones as a major factor in determining migraine r

181 gonadal secretions (commonly referred to as sex hormones), which substantially influence many aspect

182 he elucidation of complex interactions among sex hormones, sex chromosomes, and immune response genes

183 n analyses between genetic variants and age, sex, hypertension, and body mass index in the AFGen Cons

184 When adjusted to sex, hypertension, diabetes mellitus, target vessel, ser

185 After matching for age, sex, hypertension, type 2 diabetes, previous stroke, and

186 Thus, understanding how sex impacts immunity requires the elucidation of complex

187 in multilayer contact networks structured by sex in a population of European badgers Meles meles natu

188 genital samples were attributable to vaginal sex in the past week.

189 mosome in phenotypic differences between the sexes in health and disease.

190 ding to age, residence [urban vs rural], and sex) in all countries to recruit eligible children aged

191 from Ppargc1a(f/+)Alb-cre(+/0) mice of each sex, in a cell-autonomous manner, but was greater in liv

192 e study objective was to investigate whether sex influences 3'-deoxy-3'-(18)F-fluorothymidine ((18)F-

193 Evidence that sex influences dendritic morphogenesis in two models of

194 f longevity by other factors including diet, sex, insulin signalling and population density.

195 ds light on ways that genes, environment and sex interact to affect the transcriptome's response to a

196 stment for covariates and testing for an age-sex interaction.

197 Thus, sex is a potential variable to consider in defining quan

198 on; and (3) the rise in the practice of oral sex is contributing to the increased prevalence of C. tr

199 cortical neurons from rodent embryos of both sexes is distributed throughout the somatodendritic comp

200 state policies in 32 states permitting same-sex marriage with year-to-year changes in suicide attemp

201 n 15 states without policies permitting same-sex marriage.

202 All case patients were age and sex matched with control subjects.

203 = 11) and control subjects (n = 12; age and sex matched), we performed diffusion tensor imaging and

204 lth-related quality of life than an age- and sex-matched control group in the domains of self-care, u

205 first-degree relatives and pairwise age- and sex-matched controls underwent a comprehensive epilepsy

206 L/Forty-five stroke patients and 45 age- and sex-matched controls were recruited.

207 cognitively-intact patients and 21 age- and sex-matched healthy controls completed a right-hand, pac

208 In the USA, men who have sex men (MSM) are at high risk for HIV, and black MSM ha

209 (age [35-44, 45-54, 55-64, and 65-75 years], sex [men and women], geographical region [western, centr

210 Sex modified the relationship between GLS and outcome su

211 al Impression Disease Severity Score but not sex (multivariate HR 0.93; 95% CI 0.67 to 1.28).

212 e used intracellular recordings in rat (both sexes) neocortical brain slices to assess the ionic mech

213 re-dependent sex determination, in which the sex of an embryo is determined by the incubation tempera

214 .49, 95% CI: 1.21, 1.83) than was not having sex on first meeting, while living/continued communicati

215 populations mediated the effects of age and sex on gene expression, including CD8(+) T cells for age

216 There was no significant association with sex or Chinese ethnicity.

217 ding to age (among donors <70 years of age), sex, or height (among donors </=190 cm tall).

218 models of population spread are based on one sex, or include limited aspects of sex differences.

219 are not modified by parity, latitude, fetal sex, or smoking.

220 Among men who reported having 2 or more same-sex oral sex partners, the prevalence of high-risk HPV i

221 in questionnaires were older age and female sex ( P < .01).

222 nown to mediate copula formation in opposite-sex pairs [6], but have not been investigated in larger

223 re contact-traced by C. trachomatis-positive sex partners at the STI outpatient clinic in Amsterdam,

224 who reported having 2 or more same-sex oral sex partners, the prevalence of high-risk HPV infection

225 arious patient- and implant-related factors (sex, patient age, smoking, number of remaining teeth, pe

226 to 53 years) with similar prevalence in both sexes; pediatric cases (</=16 years of age) accounted fo

227 Sex pheromones facilitate reproduction by attracting pot

228 associated with older age at diagnosis, male sex, poor initial levodopa treatment response, and postu

229 Older age, female sex, preference for English, more education, health and

230 Age, sex, previous admission for lower gastrointestinal bleed

231 roportional hazards model adjusting for age, sex, race, and comorbidity.

232 Age, sex, race, and ethnicity have small effects on the Z sco

233 uated in multivariable models including age, sex, race, APOE genotype, and educational level.

234 included interactions of ECT with age group, sex, race/ethnicity, and diagnosis group.

235 n a Cox regression, while adjusting for age, sex, race/ethnicity, modified Charlson comorbidity index

236 , we examined the effect of PQ on gametocyte sex ratio as a possible explanation for this early steri

237 wenty-four hours after treatment, gametocyte sex ratio became male-biased and was not significantly d

238 We showed that sex ratio response to elevated temperature is family-spe

239 Genetic sexing revealed that fish with undifferentiated gonads w

240 Female to male sex reversal was achieved in an emerging agricultural in

241 lly leads to masculinization (female-to-male sex reversal), resulting in neomales.

242 ics requires tracking males and females (and sex-reversed individuals) separately.

243 tion that accompany interwoven variations in sex, sex chromosome complement, and brain size.SIGNIFICA

244 ng forced religious conversion, torture, and sex slavery.

245 isparities in control of CVD risk factors by sex, socioeconomic status, and level of disability.

246 ts of whom 47514 (5%) immigrated since 1985, sex, socioeconomic status, urban (vs rural) residence, a

247 That sex-biased exposure might translate to sex-specific adverse outcomes such as behavioral deficit

248 A more thorough understanding of sex-specific cardiovascular differences both at baseline

249 Similarly, current analyses revealed sex-specific changes in network connectivity and identif

250 Sex-specific comparative effectiveness of direct oral an

251 dsx) and the mechanisms by which it mediates sex-specific development in a horned beetle species by c

252 developmental-genetic mechanisms underlying sex-specific development remain poorly understood.

253 eedback regulation is essential to establish sex-specific differences in muscle metabolism and body w

254 We explored sex-specific DNA methylation in the cord blood of 39 fem

255 s that affect parental care, 8 of which have sex-specific effects, suggesting that parental care can

256 Age- and sex-specific GS quintiles were used.

257 genetic mechanisms underlying this sex bias: sex-specific heterogeneity and higher burden of risk in

258 Epidemiological data suggest that sex-specific life experiences such as pregnancy increase

259 Sex-specific mating behaviors occur in a variety of mamm

260 y altered by letrozole, the findings suggest sex-specific mechanisms of E2 signaling.SIGNIFICANCE STA

261 The contrasting patterns of sex-specific migration during these two migrations sugge

262 ination improvement were used to compare the sex-specific risk scores with other tools that have all-

263 ntiation into such a hub neuron involves the sex-specific scaling of several components of the synapt

264 This work suggests that sex-specific skin innate responsiveness to Hla and neutr

265 ion is ensured by its collaboration with non-sex-specific terminal selector-type transcription factor

266 iffer between males and females and were not sex-specifically altered by letrozole, the findings sugg

267 these disorders, the mechanisms driving the sex specificity of disease vulnerability remain unclear.

268 ctor-type transcription factors, whereas the sex specificity of dmd-3 action is ensured by the hermap

269 ns and songbirds is linked to the actions of sex steroid hormones during ontogeny but also in adultho

270 panic and Chinese ancestry, with and without sex stratification, for six traits associated with ectop

271 In the discovery cohort, sex-stratified analysis identified 2 additional genome-w

272 A sex-stratified illness-death model was applied to estima

273 Using sex-stratified multivariable-adjusted Cox proportional h

274 p between haploid-beneficial alleles and the sex that experiences haploid selection most often (e.g.,

275 We found, in acute rat OB slices from both sexes, that inhibitory synchrony is evident in the spont

276 In studies that reported sex, the total number of females was 11226 (53.2%).

277 method that can correctly assign biological sex to human remains of any age is highly desirable.

278 anatomical measurements from mice of either sex to inform modeling of sparse and filopodia-bearing m

279 onsidered "too well" were advanced age, male sex, university hospital admission, comorbidity, and low

280 In addition, having sex upon first meeting was associated with higher odds o

281 n in young, healthy human participants (both sexes) using concurrent EEG-fMRI and a sustained selecti

282 density, and aortic annulus diameter, female sex was an independent risk factor for higher fibrosis s

283 athematic equations, and the significance of sex was assessed using the Student t test.

284 for screening nor history of receptive anal sex was significantly associated with HSIL.

285 for age and CD4(+) T cells and monocytes for sex, we detected a direct effect of these intrinsic fact

286 Similar patterns overall and by sex were observed for ID.

287 Interactions by age and sex were tested, and models controlled for sociodemograp

288 no GBCA administration), matched for age and sex, were inculded.

289 than half of which occurred in men who have sex with men (MSM).

290 , female sex workers (FSW), and men who have sex with men (MSM).

291 Lastly, STIs in men who have sex with men have increased since the late 1990s.

292 n and women in South Africa and men who have sex with men remain at increased KS risk, likely due to

293 , suggesting legalisation of some aspects of sex work could reduce HIV among sex workers to the great

294 We found that the relation between sex work policy and HIV among sex workers might be partl

295 of homelessness, drug use, imprisonment, and sex work.

296 ansmission in the general population, female sex workers (FSW), and men who have sex with men (MSM).

297 lation between sex work policy and HIV among sex workers might be partly moderated by the effectivene

298 e aspects of sex work could reduce HIV among sex workers to the greatest extent in countries where en

299 ed individually with 10 people without MS by sex, year of birth, age/vital status at MS diagnosis, an

300 gher intelligence, East Asian ancestry, male sex, younger age, formal music training-especially befor