ライフサイエンスコーパス: shape change

1 umbers in a bilayered epithelium can lead to shape change.

2 rkers and TH2 cytokines, and eotaxin-induced shape change.

3 actomyosin redistribution together with cell shape change.

4 tures for cell proliferation, migration, and shape change.

5 rnover and generating the force for filament shape change.

6 udies how the cytoskeleton controls cellular shape change.

7 d, putatively, diseases associated with cell shape change.

8 ex vivo prostaglandin D2-mediated eosinophil shape change.

9 noparticle surfactants and arresting further shape change.

10 , integrin alpha(IIb)beta(3) activation, and shape change.

11 suggest a simple design rule for controlled shape change.

12 secretion, cell division, cell motility, and shape change.

13 ical rigidity to the cell and drive cellular shape change.

14 tin polymerization, platelet activation, and shape change.

15 itate retraction of membranes during dynamic shape change.

16 ination of actomyosin contractility and cell shape change.

17 rangement, apical domain elongation and cell shape change.

18 which correspond to the protein's effective shape change.

19 lets, which mediate platelet aggregation and shape change.

20 pe change, which defines the onset of tissue shape change.

21 memory polymer to regulate the time of such shape change.

22 Tissue morphogenesis is orchestrated by cell shape changes.

23 cell divisions, cell rearrangements and cell shape changes.

24 ynamics of N-BAR proteins relate to membrane shape changes.

25 s of stabilization to result in irreversible shape changes.

26 uce a variety of tissue movements and tissue shape changes.

27 ns, as well as a variety of resulting tissue shape changes.

28 process driven by asymmetric epidermal cell shape changes.

29 pal mechanistic features underlying cellular shape changes.

30 erstand the real three-dimensional nature of shape changes.

31 e-chain spectra and interference of spectral shape changes.

32 healing relies on tissue movements and cell shape changes.

33 nter the nucleus, but did cause keratinocyte shape changes.

34 polarity establishment, migration, and cell shape changes.

35 d remodeling of glia may facilitate neuronal shape changes.

36 s a novel cellular strategy for driving cell shape changes.

37 these sheets are folded and reshaped by cell-shape changes.

38 that regulate NF-kappaB in response to cell shape changes.

39 is cancelled by cell rearrangements and cell shape changes.

40 es based on their past shape despite dynamic shape changes.

41 ntractility is critical for tissues to adopt shape changes.

42 long "track" MTs, resulting in dramatic cell shape changes.

43 nce of myosin motor activity cell and tissue shape changes.

44 e show that, during these activation-induced shape changes, a dramatic HDAC6-mediated tubulin deacety

45 riven locomotion but retain the soft-bodied, shape-changing ability to explore confined environments.

46 g the FABD fully rescued morphogenesis, cell shape change, actin regulation, and viability, whereas k

47 gnificantly inhibits activation-induced cell shape changes, adhesion and recruitment to sites of infl

48 addition to these cell rearrangements, cell shape changes also contribute to tissue deformation.

49 Such molecular shape changes alter intermolecular packing and thus affe

50 During development, coordinated cell shape changes alter tissue shape.

51 These membrane reservoirs facilitate cell shape change and buffer mechanical stress, but we do not

52 issue organization and the basis of all cell shape change and cell movement in development.

53 ation and with CXCL8 to stimulate neutrophil shape change and chemotaxis.

54 the time-dependent correlation between cell shape change and intracellular factors that may play a r

55 deletion of NAP-2 markedly reduced leukocyte shape change and intrathrombus migration.

56 room3 is a potent inducer of epithelial cell shape change and is required for lens and neural plate m

57 n-based cell protrusion into persistent cell shape change and migration.

58 on-dependent cellular processes such as cell shape change and migration.

59 re likely sources of forces that direct cell shape change and movement we explicitly model the dynami

60 t to elongation at the growth zone, but cell shape change and rearrangement contribute as much as 40%

61 Independent of mew, Rac regulates cell shape change and rearrangement in the proximal gland, wh

62 atelet cytoskeleton are crucial for platelet shape change and secretion and are thought to involve ac

63 large scale tissue deformations, cell level shape change and subcellular F-actin organization and by

64 mptions by visualizing the stages of nuclear shape change and the corresponding evolution of the cort

65 many developmental processes involving cell shape change and tissue deformation.

66 od-shaped cells were committed to subsequent shape change and to becoming sonication-resistant spores

67 nlarged in inflamed tissues through pericyte shape change and were used as exit points by neutrophils

68 1-K38A eliminated this dynamic mitochondrial shape change and, importantly, blocked GSIS.

69 as a new model system for understanding cell shape change and, putatively, diseases associated with c

70 recise orchestration of cell migration, cell shape changes and cell adhesion.

71 is required within the fat body for the cell-shape changes and cell detachment that are characteristi

72 o in wild-type protoplasts generates similar shape changes and cell division.

73 ells by MK571 or probenecid resulted in cell shape changes and decreases in actin stress fibers and M

74 growing MTs are important to coordinate cell shape changes and directed migration into the surroundin

75 Nuclear shape changes and HIV inhibition both mapped to the nucl

76 siderable interspecies variation in the cell shape changes and neighbor exchanges underlying appendag

77 In addition, gross cell shape changes and organelle movements buffer local Ca(2+

78 ic arrangements of actin and, thus, for cell shape changes and process formation.

79 wild-type embryos, spatially regulated cell-shape changes and rearrangements organize cells into hig

80 sue morphogenesis requires control over cell shape changes and rearrangements.

81 m in which neurogenesis is coupled with cell shape changes and regulated steps of cell intercalation.

82 isruption of tip links, leads to stereocilia shape changes and shortening.

83 egulated by Rock proteins, disrupted KV cell shape changes and the anteroposterior distribution of KV

84 toplasm accounts quantitatively for the cell shape changes and the nucleus movement in Drosophila ven

85 /or VCAM-1 and demonstrated ICAM-1-dependent shape-change and crawling behavior.

86 ical mechanisms governing ligand-induced RNA shape-change and enables the development of cell-free an

87 the cell polarization, actin reorganization, shape change, and motility in simple gradients.

88 g of a hydrogel as the driving force for the shape change, and the temperature-dependent modulus of a

89 e result of coordinated cell movements, cell shape changes, and the organisation of pigment cells dur

90 is accompanied by a columnar-to-conical cell shape change (apical constriction or AC) and is known to

91 hese classes of mechanical metamaterials for shape change applications like morphing structures.

92 While the mechanisms underlying this shape change are now well described, the functional impo

93 Shape changes are accompanied by a significant lowering

94 Although these cell shape changes are accompanied by an apparent large incre

95 These cell shape changes are controlled by nonmuscle myosin II (NMI

96 Cell shape changes are determined by the interplay of cell wa

97 Cell-shape changes are insured by a thin, dynamic, cortical l

98 sms that translate these signals into tissue shape changes are not well understood.

99 These shape changes are shown to originate in the interplay be

100 Individual cell shape changes are the basis for the morphogenetic events

101 g cytokinesis, the cell undergoes a dramatic shape change as it divides into two daughter cells.

102 longevity pathways.Mitochondria can undergo shape changes as a result of fusion and fission events.

103 nding magnetocaloric cooling with reversible shape changes as high as 5.6% under only 1.3 T, or 3 T a

104 shape-change assay relative to the isolated shape change assay, potentially reflective of its relati

105 W039 retained its potency in the whole-blood shape-change assay relative to the isolated shape change

106 These shape changes associated with lateral intercalation beha

107 Cell-shape changes associated with processes like cytokinesis

108 and platelet aggregates stimulated leukocyte shape change at sites of endothelial injury; however, on

109 tors of innate immunity and undergo dramatic shape changes at all stages of their functional life cyc

110 Vertebrate embryos undergo dramatic shape changes at gastrulation that require locally produ

111 ion of molecular switches to stimulate rapid shape changes at the macroscale and thus to maximize act

112 raphy changes dramatically during neutrophil shape change (both locally and globally) and can be trig

113 d inhibited PGD2-stimulated human eosinophil shape change, but importantly QAW039 retained its potenc

114 he mechanical feedback systems ensure robust shape changes, but if they go awry, they are poised to p

115 Endoderm cells move by amoeboid shape changes, but in contrast to other instances of amo

116 ical actin network controls many animal cell shape changes by locally modulating cortical tension.

117 duce functional changes in a device and that shape changes can be actuated via heating of printed com

118 Similar shape changes can be generated by contraction as well as

119 eloping zebrafish embryo as their successive shape changes can be visualized in real-time in vivo.

120 inuous case, we find that sufficiently large shape changes can drive reconfiguration on timescales co

121 its rheology sets the rate at which cellular shape changes can occur.

122 e active pellicle shear deformations causing shape changes can reach 340%, and estimate the velocity

123 ables quantification of the dynamics of cell shape changes, cell interfaces and neighbor relations at

124 hormonal controls that orchestrate the cell shape changes, cell-cell junction remodeling and polariz

125 These coincide with a novel cell shape change--cell extension along the anterior-posterio

126 enhanced chemoattractant-induced eosinophil shape change, chemotaxis, CD11b surface expression, and

127 of platelet biology, including aggregation, shape change, coagulation, and degranulation, as well as

128 Here we demonstrate a new reversible shape-changing component design concept enabled by 3D pr

129 Finally, we create several 2D and 3D shape changing components that demonstrate the role of k

130 These results indicate that regional cell shape changes control the development of anteroposterior

131 Locomotion is driven by shape changes coordinated by the nervous system through

132 Cell-shape change demands cell-surface growth, but how growth

133 Net cell shape change depends on whether cell shape is stabilized

134 and PIN1a suggests that PAN2-dependent cell shape changes do not involve any of these proteins, indi

135 underlying epithelial folding involves cell shape changes driven by myosin-dependent apical constric

136 l behaviors originate from the Fermi surface shape change due to pressure-induced band inversion.

137 host red cell undergoes an abrupt, dramatic shape change due to the sudden breakdown of the erythroc

138 ion furrow can also achieve the same type of shape change during cytokinesis without myosin contracti

139 gnaling, as essential for controlling airway shape change during development through an effect on mit

140 l manner, this synctium undergoes remarkable shape change during development.

141 Tjp1a is a novel regulator of cell shape changes during colour pattern formation and the fi

142 Cell shape changes during cytokinesis in eukaryotic cells hav

143 llular matrix (ECM) adhesions regulates cell shape changes during embryonic development and tissue ho

144 omyosin accumulation that drive initial cell shape changes during gastrulation.

145 We show that when body shape changes during growth, these models make opposing

146 ent that the cell nucleus undergoes dramatic shape changes during important cellular processes such a

147 tiate the regulation of NMII to mediate cell shape changes during MHB morphogenesis are not known.

148 Here, we have quantified shape changes during mouse heart looping, from 3D recons

149 ork beneath the cell membrane, to facilitate shape changes during processes like cytokinesis and moti

150 ion and the ecological significance of brain shape changes during the evolutionary diversification of

151 Eukaryotic cells undergo shape changes during their division and growth.

152 analysis of the fast dynamics of whole-cell shape changes during tissue folding and points to a simp

153 We find that the specific sequence of cell-shape changes during VF formation is critically controll

154 a focus on open questions about kinetics of shape change, effects of block copolymer architecture on

155 s a powerful method to understand how tissue shape changes emerge from the complex choreography of co

156 n Shh(-/-) mutants, which recapitulate heart shape changes expected from a persistent dorsal mesocard

157 Platelets adherent to fibrin displayed shape change, exposure of procoagulant phospholipids, an

158 Here, we report shape changing films that are powered by DNA strand exch

159 egulate actin cortex remodeling and membrane-shape changes for cell polarization.

160 a notch (r(2) = 0.804), and the metaphyseal shape changed from flat (r(2) = 0.766) to clearly undula

161 With advancing GA, the epiphyseal shape changed from spherical (r(2) = 0.664) to hemispher

162 exposure to >/=10 mM NaCl, the in-plane AgNP shape changed from triangular to circular, the sidewalls

163 hen moving, requiring perceivers to separate shape changes from object motions.

164 e suppressive mutations lead to a major cell shape change, from the normal cylindrical shape to a bra

165 al lipid domains, often accompanied by their shape change, fusion or splitting.

166 Although conversion of light into shape changes has been reported and compared to artifici

167 FRD perturbations, whereas models with large shape changes have considerable FRD potential.

168 he physical basis for the regulation of cell shape changes, here, we use a cell-like system with a co

169 Shape-changing hydrogels that can bend, twist, or actuat

170 dependent, time-resolved information on cell shape changes (impedance) and dynamic mass redistributio

171 was normal in mutant mice, whereas platelet shape change in aggregometry was attenuated.

172 However, the role of mitochondrial shape change in cholestasis is not defined.

173 oskeleton to cell-cell junctions drives cell shape change in development and homeostasis.

174 Shape change in hydrogels has been induced by global cue

175 contributes to physiologically relevant cell shape change in intact organisms.

176 inding of Neph1 did not induce a significant shape change in Myo1c, indicating this as a spontaneous

177 genesis are controlled by genetics, physical shape change in plant tissue results from a balance betw

178 stabilization and phenocopied the attenuated shape change in response to collagen, suggesting that Ra

179 al flow, drove a lamellipodial-to-filopodial shape change in suspended cells, and induced a novel act

180 clude by describing several forces likely to shape change in the medical liability environment over t

181 llular signals, signaling pathways, and cell shape changes in a noisy background.

182 elop a general mathematical model to examine shape changes in a permeable object subject to boundary

183 tudy of chemotaxis, we demonstrate that cell shape changes in a wave-like manner.

184 t-PA also induced marked shape changes in both brain endothelial cells and astroc

185 al actomyosin contractions began before cell shape changes in both Caenorhabitis elegans and Drosophi

186 Cell shape changes in cytokinesis are driven by a cortical ri

187 a high-throughput image cytometer to assess shape changes in Escherichia coli during hyperosmotic sh

188 ynamics of these large-amplitude strains and shape changes in few-nanometre-scale particles.

189 Shape changes in plant tissues affect the pattern of str

190 ning multiple domains that undergo different shape changes in response to different DNA sequences.

191 aves undergo rapid and reversible volume and shape changes in response to extracellular hypertonic or

192 /actin filament interactions underlying cell shape changes in response to guidance cues, plays a role

193 ores have the potential to forecast imminent shape changes in the contamination pattern, even before

194 requently accompanied by protein-facilitated shape changes in the plasma membrane.

195 such interactions have been identified with shape changes in the sprouts and the associated rearrang

196 The macroscopic bidirectional shape changes in TMPAs could be correlated with changes

197 podocytes not susceptible to sema3a-induced shape changes, indicating that MICAL1 mediates sema3a-in

198 We found that platelet shape change induced by selective G(12/13) stimulation w

199 Localized cell shape change initiates epithelial folding, while neighbo

200 ethods for quantitatively decomposing tissue shape changes into cellular contributions.

201 physiological significance of mitochondrial shape change is poorly understood.

202 In a second step, the dynamic shape change is realized by cross-linking the P2VP domai

203 apical cell surfaces, and the resulting cell shape change is thought to cause tissue folding.

204 rized; however, the mechanical basis of cell shape changes is largely unknown because of a lack of me

205 The extent of these shape changes is limited by the mechanical properties of

206 The molecular basis and control of glial shape changes is not well understood.

207 At the core of cell-shape changes is the ability of the cell's machinery to

208 ntractile systems coordinate to promote cell shape changes is unclear.

209 ated after vessel injury and undergo a major shape change known as disc to sphere transition.

210 chanisms revealed impaired chemokine-induced shape change/lamellipod extension and increased integrin

211 (ECM), are known to drive cell branching and shape change largely through a myosin-II-mediated reorga

212 pical constriction is a widely utilized cell shape change linked to folding, bending and invagination

213 res strongly regulated by size, with axes of shape change linked to the actions of recently identifie

214 nd molecular motors is encapsulated within a shape-changing lipid vesicle.

215 structural systems that can achieve gigantic shape change, making them ideal as a platform for super

216 To regulate shape changes, motility and chemotaxis in eukaryotic cel

217 ownstream of Pitx2 to directly regulate cell shape changes necessary for early gut tube morphogenesis

218 ercomes cortical tension to produce the cell shape changes needed for locomotion.

219 Specific cell shape changes occur at the point of deepest constriction

220 When these drastic shape changes occur rapidly, cell volume and surface are

221 jor reorganizations, which contribute to the shape change of activating platelets.

222 ppear closely associated with the continuous shape change of mitochondria mediated by fission and fus

223 Shape change of RhoA-deficient platelets in response to

224 r and mechanical processes that underlie the shape changes of individual cells and their collective b

225 s on intracellular microtubules, we measured shape changes of individual microtubules following laser

226 t is transformed into units of strain by the shape changes of individual switches, until a threshold

227 e process in which coordinated movements and shape changes of large numbers of cells form tissues, or

228 putational model predicts the velocities and shape changes of rolling leukocytes as observed in vitro

229 Dynamic shape changes of the plasma membrane are fundamental to

230 l is generally achieved by head movements or shape changes of the sound-emitting mouth or nose.

231 The shape-change of 3D printed smart materials adds an activ

232 e quantitatively account for this wing-blade shape change on the basis of cell divisions, cell rearra

233 anching clades but thermal performance curve shape changes on shorter time scales.

234 ing, as well as other processes that require shape change or force generation.

235 her elongation mechanisms, specifically cell shape change, orientated cell division and cell rearrang

236 Moreover, quantitative analysis of filament shape change over time revealed that myosin XI generates

237 s to quantify tissue deformation and surface shape changes over the course of leaf development, appli

238 an approach for quantifying rapid whole-cell shape changes over time, and we combined it with deep-ti

239 requires precise measurements of whole-cell shape changes over time.

240 lding allows bleb inflation and dynamic cell-shape changes performed by migrating cells.

241 photopatterning, and iii) there is permanent shape change post-irradiation.

242 ingression during cytokinesis, a model cell-shape-change process.

243 orally controlled leukocyte adhesiveness and shape-changes promoting leukocyte attachment to the inne

244 Riboswitches are shape-changing regulatory RNAs that bind chemicals and r

245 Soft materials capable of programmable shape change require localized control of the magnitude

246 at the base of fissures fail to undergo cell shape changes required for fissure initiation.

247 plays an important role in the turgor-driven shape changes required for stomatal pore opening to occu

248 Specific shape changing scenarios, e.g., based on bending, or twi

249 self-fold to specified shapes in controlled shape changing sequences.

250 he electrical resistivity measurement with V shape change signals the transition from a Rashba type t

251 platform for super light-weight structures, shape-changing soft robots, morphing antenna and RF devi

252 oxLDL, but not native LDL, induced shape change, spreading, and phosphorylation of MLC (ser

253 ous microarchitectures designed for specific shape change strategies, e.g. sequential shape recovery.

254 Cell shape changes such as cytokinesis are driven by the acto

255 orce imbalance at cell contacts induces cell shape changes, such as apical constriction or polarized

256 al epithelia, including epithelia undergoing shape changes, such as the fin folds.

257 Inherent adaptability should allow such shape-changing systems to measure numerous different env

258 sterior zonules may have a greater impact on shape change than the equatorial zonule and that choice

259 Apical constriction is a cell shape change that promotes epithelial bending.

260 Apical constriction is a cell shape change that promotes tissue remodeling in a variet

261 VF formation along the same sequence of cell-shape change that we observed in the actual embryo, with

262 We investigated the apical cell-shape changes that characterize amnioserosa cells during

263 ch flexible E153-R210 links mediate capsomer shape changes that control where pentons are placed to c

264 astrulation pathway triggers epithelial cell shape changes that drive gastrulation and tissue folding

265 cytoskeleton is a major determinant of cell-shape changes that drive the formation of complex tissue

266 oskeletal rearrangements that cause the cell shape changes that drive tubulogenesis are not well unde

267 skeleton within individual cells drives cell shape changes that fold tissues.

268 ng of KV cells revealed region-specific cell shape changes that mediate tight packing of ciliated cel

269 Morphogenesis is driven by small cell shape changes that modulate tissue organization.

270 n must be maintained during the complex cell shape changes that occur during cytokinesis in vertebrat

271 e role of NMIIA and NMIIB in regulating cell shape changes that occur during MHB morphogenesis.

272 even more regulatory events driving the cell shape changes that produce tubes of specific dimensions.

273 folding/unfolding can contribute to the cell-shape changes that promote embryonic morphogenesis.

274 is stimulus, rather than causing a temporary shape change, the CAN structure responds by permanently

275 reorienting stimuli than cells with dynamic shape changes, the degree of the shape-induced effects b

276 both a-cells and alpha-cells and their cell shape changes, the extracellular diffusion of mating phe

277 d actin cytoskeletal reorganization and cell shape change; these responses could be rescued by the fo

278 cAMP)-dependent signaling modulates platelet shape change through unknown mechanisms.

279 ation of cell contractility coordinates cell shape change to construct tissue architecture and ultima

280 near the transversal ones (with more N), its shape changes to a prism.

281 tress and displacement fields with simulated shape changes to accommodation in living lenses.

282 cently developed methods for relating tissue shape changes to cell dynamics have not yet been widely

283 apices, undergo a series of coordinated cell-shape changes to form a ventral furrow (VF) and are subs

284 broader cortical areas induces proportional shape changes to growth domains, demonstrating that both

285 zation, we demonstrate how to exploit subtle shape changes to infer cell wall material properties.

286 need to coordinate spindle positioning with shape changes to maintain cell-cell adhesion.

287 ransition, in coupling moesin-dependent cell shape changes to mitotic exit.

288 ) have the ability to show large recoverable shape changes upon temperature, stress or magnetic field

289 lates between two defect configurations, and shape-changing vesicles with streaming filopodia-like pr

290 )-mediated inhibition of thrombin-stimulated shape change was accompanied by diminished phosphorylati

291 The mechanical nature of this shape change was confirmed by polyhedrocyte formation fr

292 on, but neither additional eyespots nor wing shape changes were observed in forewings as expected of

293 onally modelling Ca(2+) release, endothelial shape changes were shown to alter the geometry of the Ca

294 it slightly enlarged meshwork faces and some shape changes, whereas LB1-deficient nuclei exhibit prim

295 (AC) is a widely utilized mechanism of cell shape change whereby epithelial cells transform from a c

296 tural basis for the known dramatic molecular shape change, whereby the molecular length can increase

297 d nanoparticles initiates a rapid isothermal shape change which triggers the activation of multiple f

298 nsition from reversible to irreversible cell shape change, which defines the onset of tissue shape ch

299 rial architectures that exhibit programmable shape changes with temperature and time.

300 s, as they undergo large reversible uniaxial shape changes, with strains of 20-500% and stresses of 1