ライフサイエンスコーパス: shed

1 Compared with baseline, genital HSV-2 shedding rates immediately after dosing were reduced wit

2 e of Developmental Cell, Majda et al. (2017) shed light on how the jigsaw shape can arise from locali

3 tly published in Nature, Brown et al. (2017) shed new light on how the skin handles the activation of

4 n, Liu et al. (2017) and Huynh et al. (2017) shed new light on this important question.

5 Understanding the function of Nectin-4 shedding in ovarian cancer progression is critical to fa

6 HHV-6 shedding rate and viral load were similar between childr

7 the role of the Asp358Ala variant in sIL-6R shedding from neutrophils and its pro-inflammatory effec

8 nical relevance of this ADAM17-mediated ACE2 shedding in hypertensive patients and further identify t

9 ype 1 receptors promote ADAM17-mediated ACE2 shedding in the brain of hypertensive patients, leading

10 ed between PIVs and persistent low-level AdV shedding may account for the higher method discordance o

11 In this issue, Pontes et al. shed new light on how the interplay among membrane tensi

12 n this issue of Cancer Cell, Sheltzer et al. shed new light on Theodor Boveri's century-old hypothesi

13 ly contribute to modern sericulture but also shed light on future antiviral therapy.IMPORTANCE Pathog

14 The kinetics experiments also shed light on the effects of chloride concentration on r

15 Results from our analyses shed light on the physiological role of the type-B ARRs

16 Our structural and biochemical analysis sheds new light on the molecular basis for IFIT1 transla

17 variate but also with multivariate analysis, shed more light on the analysis of samples as they occur

18 hat have leveraged biosynthetic advances and shed light on the mechanism of action of clb metabolites

19 echanisms controlling these associations and shed light on the stepwise acquisition of this genetic t

20 pects of Blimp1's role in T cell biology and shed light on the intricate mechanisms regulating Treg a

21 the arrangement of Wnt-FZD CRD complexes and shed structural insights that could aide in the identifi

22 asis for the derived chimaeroid cranium, and shed new light on the chondrichthyan response to the ext

23 ulating MSC fate during root development and shed light on how BMP signaling can achieve functional s

24 a novel bacterial selenoprotein family, and shed additional light on the phylogenetic distribution o

25 s identified here will advance the field and shed light on why defence traits shift so dramatically a

26 E has potential to improve reading frame and shed light on A-site occupancy in ribosome profiling exp

27 bility framework for data-driven PP-GLMs and shed new light on the stochastic dynamics of state-of-th

28 ic insights important for HLHS pathology and shed new insights into the role of this pathway during h

29 the temperature sensitivity of SA11-tsC and shed new light on functional protein-protein interaction

30 ; and factors influencing concentrations and shedding rates of pathogens originating from animal fece

31 TAM expression and shedding by tubular epithelial cells were investigated b

32 anding of this specialized enzyme family and shedding critical light onto the biosynthesis of bioacti

33 fic regulation of inflammation mediators and shedding new light on the role of fibroblasts in chronic

34 lux of chemokines through the regulation and shedding of syndecans.

35 rstanding of membrane protein biogenesis and sheds light on the role of TRAP in human congenital diso

36 Brocadia and sheds light on their metabolism in engineered ecosystems

37 irst of a sactionine bond forming enzyme and sheds light on structures and mechanisms of other member

38 g among genetically distinct individuals and sheds light on possible phenotypic consequences of such

39 ineates the signaling network of PfCDPK1 and sheds light on mechanisms via which it regulates invasio

40 d-latitude terrestrial and marine sites, and sheds light on the long-distance transport of tephra in

41 s a large number of experimental studies and sheds light on a novel therapeutic avenue to target dise

42 ization of neurotransmitter transporters and sheds light on their drug modulation.

43 in crystallographic bond lengths and angles shed light on the structural changes accompanying oxidat

44 P0) >/=five days, 4/6 direct-contact animals shed the H9N2:pH1N1 (P7).

45 Interestingly, those four animals shed virus with titers similar to those of the pH1N1, wh

46 ains (NfL) are unique to neuronal cells, are shed to the cerebrospinal fluid (CSF), and are detectabl

47 ms on cell bodies, and their ectodomains are shed by metalloproteinases in response to NMDA receptor

48 he 100S complexes in Gram-positive bacteria, shedding light on the mechanism of translation suppressi

49 nized pups required high levels of bacterial shedding in nasal secretions and was temporally correlat

50 gies to be useful, the quantity of biomarker shed into the blood and its relationship to tumor growth

51 omarker kinetics that accounts for biomarker shedding from tumor and healthy cells, biomarker entry i

52 Reaction kinetics and DFT calculations shed light on the mechanism of the reaction and explain

53 2Ce32Al16Ni5Cu15 bulk metallic glass and can shed new light on the mechanisms of polyamorphism and st

54 The geographic distribution can shed light on where an allele first arose, what populati

55 etic variants influencing sleep patterns can shed light on the physiological processes underlying sle

56 In this area, CARP sheds new light on some old problems.

57 xtending the approach to treatment of cattle sheds, or deploying other tactics that target zoophilic

58 e patients stimulated ADAM17-dependant CD163 shedding from healthy donor-derived monocytes.

59 s to protect HG MKs from apoptosis and CD42b shedding, we also demonstrate that apoptosis precedes CD

60 so demonstrate that apoptosis precedes CD42b shedding and that apoptosis inhibition enriches the FV(+

61 osis and glycoprotein Ib alpha chain (CD42b) shedding.

62 e demonstrate the prognostic impact of CD62L shedding from T cells and increased sCD62L plasma levels

63 Bonding characteristics shed light on the reasons for the very different stabili

64 edding vs. intensity and duration of chronic shedding in individuals.

65 s, the subtle dynamical influence of chronic shedding relative to more obvious epidemic drivers, and

66 demonstrations of the importance of chronic shedding to pathogen persistence at the population-level

67 effects of population prevalence of chronic shedding vs. intensity and duration of chronic shedding

68 Studying chronic shedding using commonly collected disease data is hamper

69 infection and validated them using clinical shedding data.

70 CMV shedding rate and viral load were higher in children wit

71 ly detected self-limited, low-level oral CMV shedding events, which we termed transient CMV infection

72 The structure of the complex sheds light on the mechanism of selectivity in extracell

73 These novel compounds shed light on the role of functional selectivity at the

74 netic analysis of paired specimens confirmed shedding of 2 distinct HSV-2 strains collected at differ

75 understanding its genome architecture could shed light on plant adaptation and genome evolution.

76 s a safe, rapid imaging technique that could shed light on the pathogenesis of rare diseases of the o

77 tion relies on circulating tumor DNA (ctDNA) shed from tumor deposits into circulation.

78 Phagocytosis of daily shed photoreceptor outer segments is an important functi

79 Genomic data shed new light on transmission dynamics and can be used

80 These data shed important insights on the emergence of viruses with

81 These data shed new light on the important role astrocytic EAAT2 pl

82 Analysis of Deltam sheds light on the mass balance (in addition to the char

83 indings support a role for MT3-MMP-dependent shedding of NgR1 in regulating excitatory synapse develo

84 The results as described shed a useful light on the reactivity, appearance, and r

85 Despite shedding of the bacteria, the remnant matrix remains int

86 n addition to new archeological discoveries, sheds light on the origin of this important crop and pro

87 brane molecule, it also undergoes ectodomain shedding to become a synaptic basal lamina component.

88 novel Col13a1tm/tm mice in which ectodomain shedding is impaired.

89 The eDNA shedding and decay rates reported within are the first f

90 he universality and robustness of the effect shed new light on the MIT in complex oxides.

91 influences the observed enantioselectivity, shedding light on the success of this emerging ligand cl

92 in asthma and is characterized by epithelial shedding, goblet cell hyperplasia, basement membrane thi

93 omes from additional members of this family, shedding new light on their unusual biology.

94 pread beyond the respiratory tract and fecal shedding.

95 rovirus (MNoV) infection and regulates fecal shedding and viral titers in tissue.

96 al tissue titers and enhanced reovirus fecal shedding.

97 This finding sheds light on how eukaryotes utilize RNA to repair chro

98 This finding sheds light on mechanisms underlining p63 function in th

99 More generally, our findings shed light on evolutionary mechanisms that give rise to

100 Collectively, our findings shed light on how mammalian dynein complexes associate w

101 Our findings shed new light into understanding of ovarian carcinomas

102 Our findings shed new light on the regulation of a key cholesterol sy

103 These findings shed light on a novel role for this conserved domain in

104 These findings shed light on the epigenetics and cellular origins of li

105 These findings shed light on the formation of physiological extracellul

106 These findings shed new light on the diversity of primate vocalizations

107 These previously unrecognized findings shed light on the intricacies underlying the contributio

108 .6% of visits with detectable VL had genital shedding.

109 ons was used to assess predictors of genital shedding among women with undetectable plasma viral load

110 Predictors of genital shedding were HIV disease stage, antiretroviral regimen,

111 tomers were occupied by the CD4mc, and gp120 shedding from the Env trimer was increased in the presen

112 Although crystallography has shed light on the mechanism of mC flipping by SRA, tools

113 ureus obtained by X-ray crystallography have shed light on fine details of drug binding sites and hav

114 Recent experiments have shed light on this question by showing that, hidden with

115 d insights from the basic neurosciences have shed important new light on how sleep and Abeta homeosta

116 lex with key host cell binding partners have shed light on protein-protein interactions critical to N

117 The results have shed further light and provided additional clarification

118 Previous studies have shed light on post-transcriptional synaptic NMDAR mediat

119 Previous studies have shed light on the factors influencing bird migration but

120 of genetic and cell biological studies have shed light on the question-the site of BDNF release at t

121 res, and emerging analytical techniques have shed light on nuanced and context-dependent nano-bio int

122 Advances in imaging techniques have shed new light on the structure of vesicles formed by CO

123 They have shed light on the pathogenesis of different amyloid type

124 larizability, and orbital energies, can help shed light on the energetic, physical, and spectroscopic

125 This research helps shed light on the movement of populations across the con

126 rom a biological perspective, our work helps shed light on how ants and other social insects can obta

127 lence risk ratios (adjPRR) of detectable HIV shedding (VL > 40 copies/mL) were estimated by Poisson r

128 Among children with RTI, the median HMPV shedding time by PCR was 13 days (range, 6-28 days), but

129 30 microg and 100 microg reduced genital HSV shedding and lesion rates.

130 ers an interpretation of feature importance, shedding light on the driving forces of the underlying b

131 Results of these incubations shed new light on nitrogen cycling complexity and possib

132 simplex virus 1 (HSV-1)-infected individuals shed the virus in their body fluids following reactivati

133 ated platelets and endothelial cells induces shedding of the P-selectin ectodomain into the circulati

134 Rather, activation intensity shed insight on the level of mental effort, i.e., how ha

135 Cell-free DNA (cfDNA) is shed into the blood by tumor cells undergoing apoptosis

136 Pathological examination shows that ChHV5 is shed in skin.

137 Importantly we show that TRAILshort is shed in microvesicles into the cellular microenvironment

138 e virus appear to correlate with urinary JCV shedding and serostatus.

139 Escape into the cytosol and outer-layer shedding depend on interaction of a hydrophobic surface

140 ions, characterized by persistent high-level shedding, viremia, and seroconversion.

141 ic gene expression and plasma protein levels sheds light on potential disease mechanisms.

142 Longitudinal shedding rates were determined by Kaplan-Meier survival

143 a metalloproteinase inhibitor inhibited LRP1 shedding and significantly attenuated RAP-induced cytoki

144 TACE is a major shedding protease, responsible for the liberation of the

145 gulation during axonal morphogenesis and may shed light on MAP7 function in neurological disorders.SI

146 newly defined role of cytoplasmic Cl(-) may shed light on the mechanisms of intracellular Cl(-) sign

147 These findings may shed light onto obesity-related cardiac remodeling and h

148 ssed lncRNA landscape characterized here may shed light into normal biology and lung adenocarcinoma p

149 pecific allele frequency possible, which may shed light on selection of candidate variants for rare d

150 TACE; ADAM17, CD156b), the metalloproteinase shedding CD62L, was increased at diagnosis and significa

151 atterns of the foraging behaviour that might shed a light onto development of Roman roads in the Balk

152 The use of the novel Crwn-THF moiety sheds lights in the design of novel PIs.

153 Exposure of P1 ECs to MPs shed from senescent P3 cells or circulating MPs from ACS

154 wever, we need to know how much eDNA mussels shed into their environment and how long the eDNA persis

155 oire of oxidative stress genes in S. mutans, shedding new light on the role of Spx regulation.

156 gmented epithelium (RPE) is the clearance of shed photoreceptor outer segments (POS) through a multis

157 tectable (P = .195), though the magnitude of shedding significantly increased (P = .04).

158 Prevalence of shedding did not vary by time since ART initiation when

159 Our findings not only shed light on how the tumor microenvironment contributes

160 Taken together, our study not only shed light on the mechanism by which glucocorticoid impa

161 This not only sheds new light on how efficient nature is in preventing

162 We characterized kinetics of oral shedding during primary and chronic infection for each v

163 Each HHV has a distinct pattern of oral shedding which depends partially on the age and immune s

164 ong-term potentiation at mossy cell outputs, shedding light on their mysterious function.

165 nization by C. rodentium, prolonged pathogen shedding, exaggerated cytokine responses, and greater ti

166 ause of gastroenteritis, can be persistently shed during infection, but its in vivo cellular tropism

167 earance of megakaryocytes following platelet shedding and constrains platelet lifespan in the circula

168 n crucial to understanding the role of prion shedding in disease transmission and for diagnosis.

169 to P4, and was associated with a progressive shedding of procoagulant MPs.

170 performed to evaluate factors for prolonged shedding (>/=21 days).

171 conditioning were associated with prolonged shedding.

172 m mouse to human and used parameters for PSA shedding and prostate cancer.

173 ut not all, of the capsid protein is rapidly shed in tissue culture and primary target cells, indepen

174 phils showing signs of increased reactivity: shedding of l-selectin, CD11b upregulation, increased ox

175 F, and the CusBA complex have been resolved, shedding some light on the efflux mechanism underlying t

176 Our results shed crucial insights into the mechanisms through which

177 Our results shed light on black phosphorus degradation which can aid

178 Our results shed light on the intricate structural and functional re

179 Our results shed light on the mechanisms that underpin decision-maki

180 Our results shed light on the network architectures that underlie ex

181 Our results shed light on the unusual role of zeroth LLl mode in tra

182 Our results shed new light on the interaction between metabolism, im

183 Our results shed new light on the ways in which gene flow reshaped E

184 The results shed light on the molecular mechanisms underlying its ab

185 The results shed light on the prevailing mechanistic uncertainties i

186 Together the results shed light onto binding of the precursor peptide and the

187 These results shed light on how to avoid the trap of parochialism and

188 Together, these results shed light on the function of CPSF in mediating PAS-depe

189 Collectively, these results shed light on the mechanism by which beta-III-spectrin,

190 These results shed new light on the function of Parkin in vivo.

191 Together, these results shed new light on the mechanisms by which missense mutat

192 These results shed new light on the origins of the pathway complexity

193 These results shed some light on how SP-C-induced lipid perturbations

194 Collectively, these results shed the light on the repertoire of IFNs in avian specie

195 The mean levels of influenza viral RNA shedding in asymptomatic and paucisymptomatic cases were

196 The duration of viral RNA shedding was shorter and declined more rapidly in paucis

197 edicts for poor prognosis of esophageal SCC, shedding light upon the tumor promoting oncogenic aspect

198 o and in vitro, including reduced l-selectin shedding, oxidative burst, chemotaxis, neutrophil extrac

199 rhydrophobic surface for enhancement by self-shedding and sweeping of condensate.

200 amics of condensate that the continuous self-shedding and sweeping effectively remove the droplets fr

201 The identification of this pore binding site sheds light on the mechanism of barbiturate inhibition o

202 intranasal inoculation, both animal species shed the vaccine viruses for a limited time but without

203 n regulating responses to rewarding stimuli, shedding light on the broader neurobiology of emotions a

204 Our studies shed light onto the antimicrobial mechanisms of Ctn and

205 Taken together, our studies shed new light on the role of mRNA splicing genes in the

206 Moreover, our study shed light on the importance of AAAs and might provide n

207 Therefore, not only does this study shed further light into the complexity of colorectal car

208 This proof-of-concept study sheds light on genotype-phenotype interactions, using ra

209 Collectively, our study sheds light on a conserved strategy by the viral protein

210 Hence, our study sheds light on cellular membrane biophysics by underscor

211 Our study sheds light on the nonlinear response of a circumpolar s

212 Our study sheds light on the regulation of Rab12 activation and la

213 are important for social behavior, our study sheds light on the specific nature of their interaction,

214 In conclusion, our study sheds light on the structural and biological properties

215 id, quantitative, and independent, our study sheds new light on the interpretation of previous basin

216 This study sheds light into the as yet unrevealed action of PFOS on

217 This study sheds light on the agricultural economy that underpinned

218 This study sheds light on the biology and ecology of basal fungi in

219 This study sheds light on the design of radiation-tolerant material

220 This study sheds light on the molecular evolution of viruses by cle

221 This study sheds lights on a deformation mechanism in metals with h

222 This study sheds new light on how differences in food availability

223 This study sheds new light on the heterogeneity and complexity of M

224 Naked surgeons shed fewer bacteria into the operating room environment

225 A new imaging technique sheds light on how cilia regulate their length and growt

226 evelopment of cortical interneurons and that shed light on when their fate is determined, on the infl

227 d an allelic series of GmSHMT08 mutants that shed new light on the mechanistic aspects of GmSHMT08-me

228 Here, we review recent studies that shed light on endogenous sources of mutation and epigeno

229 is made on existing comparative studies that shed light on the effect of nanoparticle anisotropy on t

230 Furthermore, we argue that shedding light on the interplay between number and conti

231 Here, we report a fossil biota that sheds new light on these issues.

232 pmental lens, we review recent evidence that sheds light on the origin and developmental unfolding of

233 el for Hel308 translocation along ssDNA that sheds light on how superfamily 1 and 2 helicases turn AT

234 res, we also performed a modeling study that sheds light on the crucial interactions for both the aff

235 Introduction of the shed ectodomain of NgR1 is sufficient to accelerate exci

236 This approach enabled us to discriminate the shedding of prions in saliva and the detection of prions

237 tion of PI(4,5)P2, a reaction needed for the shedding of endocytic factors from their membranes.

238 However, secreted MMP-7 participated in the shedding of Syndecan-4 from the surface of B-lymphocytes

239 Studying the shedding of cell membrane-bound hTNF by Adam17, a known

240 Our electronic band theory sheds new light on known topological insulators, and can

241 g attention by changing choice bias, thereby shedding new light on how the brain mediates attention.

242 Our findings therefore shed light on variation between iPSC lines and illustrat

243 An-based extended structures and, therefore, shed light on possible optimization of nuclear waste adm

244 They shed light on the involvement of these lymphatic changes

245 We show that the consequence of this shedding can be the production of inflammatory mediators

246 Many vertebrates replace teeth through shedding of the functional tooth.

247 To shed light on the processes underlying the emergence of

248 To shed light on these mechanisms, we performed patch-clamp

249 To shed light on this issue, we examined the motions of thr

250 riants associated with complex traits and to shed new insights on underlying biology, in addition to

251 Collectively, we attempt to shed light on shared and divergent neuroimaging effects

252 In an attempt to shed more light onto the pathogenesis of PTFL, an integr

253 gs that are specific to LMS and has begun to shed light on the similarities and possible unique aspec

254 tion and density, and neural connectivity to shed light on the effects of bilingualism in vivo in Alz

255 rom two shelter facilities and determined to shed atypical EPEC at a culture-based prevalence of 18%.

256 multisensory brain regions is fundamental to shed light on their neuronal operations.

257 otations are growing and can be harnessed to shed a new light on psychiatric disorders.

258 ges during APEC infection, which may help to shed light on the roles of these recently identified gen

259 These findings help to shed light on the underlying mechanisms of cardiac alter

260 rticle X-ray scattering has the potential to shed light on key biological processes.

261 vironmental microbiomes has the potential to shed light on the richness of bacterial biosynthetic div

262 egation patterns in parents and siblings, to shed new light on aetiology.

263 , and phosphatase enzyme activity in soil to shed light on potential effects of climate change on pho

264 ized the Xenopus oocyte expression system to shed light on how CFTR channel activity is reduced by SM

265 se advanced molecular dynamics techniques to shed light on these nonclassical effects, which are ofte

266 e Change Institute, has already been used to shed light on our flawed understanding of natural levels

267 In addition to shedding light on this critical process, these findings

268 the distinct anomeric fragment ions, in turn shedding light on gas-phase dissociation mechanisms of g

269 , but the mechanism and significance of uPAR shedding remain obscure.

270 genicity through tissue factor upregulation, shedding of procoagulant MPs, endothelial nitric oxide s

271 determined by severity and length of vaginal shedding, WT C57BL/6 and HLA-DR4 mice were significantly

272 Viral shedding was detected in only six (6%) of 101 participan

273 n different degrees of lung damage and viral shedding.

274 tment showed a significant decrease in viral shedding at day 3 relative to monotherapy, this differen

275 inal tissue viral titers and increased viral shedding in the stool.

276 We compared the patterns of influenza viral shedding between these groups.

277 The presence of influenza viral shedding in patients with influenza who have very few or

278 inued protection against infection, no viral shedding, and boosting of the immune response.

279 to moderate diarrhea, lower titers of viral shedding, and no mortality, whereas the icPC22A virus ca

280 and will evaluate the effect of 4b on viral shedding from sanctuary sites in EBOV survivors.

281 d with a significant reduction in both virus shedding and recurrent corneal herpetic disease.

282 y infected with BoHV-1, culminating in virus shedding and transmission.

283 solution of viremia and termination of virus shedding in oropharynges and feces.

284 Moreover, we shed new light on TLR4-TLR6 assembly and localization an

285 anscriptomes across 37 deuterostome taxa, we shed light on the evolution and diversity of TLR pathway

286 er relevant appressorium-forming fungi which shed light on how glycerol is synthesized and how appres

287 Identifying who infected whom sheds considerable light on transmission patterns, high-

288 Moreover, it will shed light on how GPCRs selectively couple to and activa

289 ation and specification in the pancreas will shed light in the origins of pancreatic diseases and may

290 It is our hope that these results will shed light on biological interactions as well as provide

291 In the end, this review will shed light on how regulatory systems, although seemingly

292 This work will shed light on the development of materials with high irr

293 fter 60 minutes, pigs were resuscitated with shed blood and crystalloid.

294 Our work sheds further light on chondrocyte-specific SOX9 express

295 ciprocity and isolation to statics, our work sheds light on energy propagation in nonlinear materials

296 Our work sheds light on how nuclear organization and Polycomb gro

297 This work sheds light on regions of low complexity often found nea

298 y associated with sex differences, this work sheds light on ways that genes, environment and sex inte

299 This work sheds new light on the limitations of the CD45.1/CD45.2

300 This work sheds new light on the role played by water in the ADOR