ライフサイエンスコーパス: short hairpin RNA

1 TGFBR2 were knocked-down in CRC cells using short hairpin RNA.

2 by lentiviral expression of a Cx43-specific short hairpin RNA.

3 fects were abolished after TGR5 reduction by short hairpin RNA.

4 2, BCL-XL and DAD1) was downregulated by BTK short hairpin RNA.

5 been knocked down with lentivirus-transduced short hairpin RNA.

6 containing RNA via microRNA 30 (miR30)-based short hairpin RNAs.

7 rexpressed in human PDAC tumor samples using short hairpin RNAs.

8 s by using in vivo gene delivery of specific short hairpin RNAs.

9 nhibited by three different mechanisms: InsR short hairpin RNA, a small InsR-blocking peptide, S961 a

10 no-associated virus (AAV) vector producing a short hairpin RNA (AAV.sh.p11).

11 migration of the TNBC cell lines expressing short hairpin RNA against CDCP1.

12 d viral vectors encoding Cre recombinase and short hairpin RNA against Crb2.

13 n adeno-associated viral vector expressing a short hairpin RNA against Homer1 mRNA (AAV-shHomer1).

14 ferentiating mouse embryonic stem cells, and short hairpin RNA against IDAX increases TET2 protein ex

15 ng factors (Oct4, Klf4, Sox2, and c-Myc) and short hairpin RNA against p53 ("4-in-1 CoMiP").

16 nd in BE(2)-M17 cells stably transduced with short hairpin RNA against PINK1.

17 ophages nucleofected with plasmid containing short hairpin RNA against PKCalpha showed markedly reduc

18 Stable knockdown of PDE10 by short hairpin RNA also inhibits colony formation and inc

19 sAC knockdown by tetracycline-inducible short hairpin RNA also prevented BSIA.

20 -kappaB activation is inhibited by anti-RIP2-short hairpin RNA and by the expression of a RIP2 CARD-o

21 cific inhibition of HER2 using an inhibitor, short hairpin RNA and dominant-negative mutant HER2 abol

22 he expression of Munc13-2 in B6 mice using a short hairpin RNA and found this recapitulated the presy

23 Finally, we report that anti-Fsp27 short hairpin RNA and PPARalpha agonists synergize to am

24 transduced with lentivirally expressed N-Ras short hairpin RNA and pulsed with L. major-expressed MAP

25 as well as viral vector-mediated delivery of short hairpin RNAs and artificial microRNAs.

26 n-coding complementary DNAs but also include short hairpin RNAs and microRNA genes, thus broadening t

27 microinfusion of a lentivirus harboring PERK Short hairpin RNA, and pharmacological inhibition was ac

28 he CDO1/CSA axis using a lentiviral-mediated short hairpin RNA approach resulted in significant tumor

29 Finally, FoxO3a silencing using a lentiviral short hairpin RNA approach significantly reduced hypoxic

30 Recent work using short-hairpin RNA approaches in vitro suggest that the p

31 r complex, or expression of a c-Jun-specific short hairpin RNA attenuated pregnenolone sulfate-induce

32 Crh-short hairpin RNA, but not control short hairpin RNA, gi

33 ilon using a selective chemical inhibitor or short hairpin RNA complements the effects of idelalisib,

34 AL1 in erythroid K562 cells using lentiviral short hairpin RNA, compromising its association in the b

35 chymal delivery of an adeno-associated virus-short hairpin RNA construct was sufficient to markedly a

36 and in the LAD2 MC line by using lentiviral short hairpin RNA constructs.

37 In contrast, short-hairpin RNA depletion of GRIN2A in mutant cell lin

38 decreasing expression of HER3 or HER4 using short hairpin RNAs did not block the induction of G2/M a

39 se targets with small molecule inhibitors or short hairpin RNA diminished the proliferation of patien

40 Depletion of P85 by P85-specific short hairpin RNAs disrupts their interaction and dimini

41 activities by specific inhibitors as well as short-hairpin RNA downregulation of beta1 integrin signi

42 The combination of two short hairpin RNAs (dual-shRNA) against different coding

43 Knockdown of DHX15 expression by short hairpin RNA efficiently reduced the ability of mye

44 fects were further confirmed using p22(phox) short-hairpin RNA-engineered HeLa cells and Nox2(-/-) co

45 Lentivirally expressed SHP-1 short hairpin RNA enhanced the CD40-induced L. major par

46 beta1-mediated cytostasis evident in control short hairpin RNA-expressing HK-2 cells.

47 Crh-short hairpin RNA, but not control short hairpin RNA, given into the central nucleus of the

48 Control short hairpin RNA had no effect on these TGF-beta1-induc

49 bitor Torin1 or by downregulation of mTOR by short hairpin RNA had no impact on FcepsilonRI-induced d

50 in-D1 and c-Myc, while silencing EphA2 using short hairpin RNA had the opposite effect.

51 Gene therapy with a virus encoding Salv short hairpin RNA improves heart function when delivered

52 Silencing TCTP by short hairpin RNA in breast carcinoma MCF-7 cells leads

53 ER2 using either IGF-1R antibodies or IGF-1R short hairpin RNA in combination with trastuzumab result

54 Reduction of KLF13 with short hairpin RNA in differentiating HPV-positive cells

55 Use of short hairpin RNA in ESC demonstrated that DNA methyltra

56 igen-specific T cells during infection using short hairpin RNAs in a microRNA context (shRNAmir).

57 Knockdown of Tip60 with short hairpin RNAs in cells that maintain HPV episomes b

58 ing of TREX1, SAMHD1, RNASEH2A, and ADAR1 by short hairpin RNAs in human neural stem cell-derived ast

59 ion to the nucleus, and knockdown of MITF by short hairpin RNA indicated its absolute requirement for

60 encing of both PYCR1 and PYCR2 by expressing short hairpin RNAs induced defects in cell proliferation

61 cell motility, while depletion of STIM1 with short hairpin RNA inhibited CRC cell migration.

62 Depletion of PKCdelta with short hairpin RNA inhibited ligand-induced growth in bot

63 ngiogenesis in Matrigel plugs, while p56/Lck short hairpin RNA inhibited the antiangiogenic effect of

64 In contrast, short hairpin RNA inhibition of AGS3 enhanced CXCL8-indu

65 Further, reconstitution with short hairpin RNA-insensitive SLC25A23 cDNA restores mit

66 nt of ATF2 or expression of an ATF2-specific short hairpin RNA interfered with TRPM3-mediated stimula

67 rest, and that reducing DHX33 levels through short hairpin RNA interference has the same effect.

68 n pharmacologically or knocking it down with short hairpin RNA interferes with ciliogenesis.

69 ere versus monolayer cells with a lentivirus short hairpin RNA kinome library.

70 Adenovirus-short hairpin RNA knockdown (KD) of Syt-7 in human islet

71 manipulations through small interfering RNA/short hairpin RNA knockdown and ectopic expression, west

72 Furthermore, using a short hairpin RNA knockdown approach, we observed that t

73 duced pluripotent stem cell (iPSC) and MeCP2 short hairpin RNA knockdown approaches to identify novel

74 null HSPC phenotype, as both in vitro Dnmt3a short hairpin RNA knockdown assays and a genetic haploin

75 increased LNCaP proliferation, whereas PSGR short hairpin RNA knockdown inhibited proliferation and

76 Skin of CTSH-deficient mice and CTSH short hairpin RNA knockdown keratinocytes showed reduced

77 Short hairpin RNA knockdown of Chrna7 in the DG enhanced

78 Short hairpin RNA knockdown of Gp78 in HT-1080 fibrosarc

79 s) and pharmacologic (imatinib) and genetic (short hairpin RNA knockdown of IL4RA and ABL1) approache

80 relevant to Ca(2+) reabsorption in vivo, as short hairpin RNA knockdown of NDPK-B leads to decreased

81 Short hairpin RNA knockdown of NEDD4 elevated HER3 level

82 C3-deficient macrophages and fibroblasts and short hairpin RNA knockdown of NLRC3 in THP1 cells.

83 Short hairpin RNA knockdown of RNase L allowed us to dis

84 Lentiviral short hairpin RNA knockdown of scavenger receptor class

85 Adeno-associated virus-mediated short hairpin RNA knockdown of Tm6sf2 in mice increased

86 Lentiviral short hairpin RNA knockdown of vimentin led to a signifi

87 FABP4 inhibition using FABP4 short hairpin RNA knockdown or a small molecule inhibito

88 ing PHD3 expression or catalytic activity by short hairpin RNA knockdown or pharmacological inhibitio

89 te cell cultures RAPTOR upregulation or AKT1 short hairpin RNA knockdown reduced expression of the pr

90 in kinase CbetaII (PKCbetaII) by CPG53353 or short hairpin RNA knockdown severely inhibits chemoattra

91 P14-deficient T cells was attenuated by TAB1 short hairpin RNA knockdown.

92 Short-hairpin RNA knockdown of Mybpc3 mRNA in wild-type

93 Using short-hairpin RNA knockdown/rescue, we find that palmito

94 pholino-mediated knockdowns in zebrafish and short hairpin RNA knockdowns in U937 cells cultured with

95 Depletion of FOXO1 with short hairpin RNA led to almost complete resistance to c

96 e and natural reward using viral delivery of short hairpin RNAs (lenti-shCRFR1) and investigate the e

97 We infected cardiomyocytes using a short hairpin RNA lentivirus library in which the mouse

98 Through screening a short hairpin RNA library, we found that RARgamma was es

99 Knockdown of Atg7 in AML cells using short hairpin RNA markedly increased apoptosis and DNA d

100 mutation in Npas2 and adeno-associated virus-short hairpin RNA mediated knockdown of Npas2 and Clock

101 s induced from Ink4a/Arf-null astroglia, and short hairpin RNA-mediated acute knockdown of p16Ink4a a

102 stasis, combined with an inducible system of short hairpin RNA-mediated Akt isoform knockdown in huma

103 Short hairpin RNA-mediated depletion of C3G in epithelia

104 Conversely, short hairpin RNA-mediated depletion of CHES1 increases

105 Initial studies revealed that short hairpin RNA-mediated depletion of the HIF1beta in

106 Short hairpin RNA-mediated down-regulation of Puma confe

107 ell as two independent methods of lentiviral short hairpin RNA-mediated gene knockdown in primary CD4

108 ransient inactivation of the gp78 complex by short hairpin RNA-mediated gene silencing causes signifi

109 Short hairpin RNA-mediated inhibition of PTX2 levels in

110 However, short hairpin RNA-mediated knockdown (KD) of Usp9x in my

111 Using short hairpin RNA-mediated knockdown in human cell lines

112 CL cell lines, CC-122-induced degradation or short hairpin RNA-mediated knockdown of Aiolos and Ikaro

113 Short hairpin RNA-mediated knockdown of Bnip3 in culture

114 which was abrogated by Ca(2+) chelators and short hairpin RNA-mediated knockdown of CnAbeta mRNA.

115 -mediated knockout and doxycycline-inducible short hairpin RNA-mediated knockdown of EXT1, a critical

116 Furthermore, short hairpin RNA-mediated knockdown of hypothalamic LDH

117 gh) ALL cell lines, which was antagonized by short hairpin RNA-mediated knockdown of Mer.

118 sor of myofibroblast differentiation, stable short hairpin RNA-mediated knockdown of Purbeta in cultu

119 ific RalA and p27 mutants, complemented with short hairpin RNA-mediated knockdown of Ral downstream s

120 Furthermore, a short hairpin RNA-mediated knockdown of SIRT3 in human m

121 ccelerated by heterozygosity for Suz12 or by short hairpin RNA-mediated knockdown of Suz12 or Ezh2.

122 Although short hairpin RNA-mediated knockdown of the STAT5A and S

123 Furthermore, short hairpin RNA-mediated knockdown of vinculin also at

124 ell proliferation in vitro and in vivo while short hairpin RNA-mediated knockdown or pharmacologic in

125 g with its expression or function, either by short hairpin RNA-mediated knockdown or with a fragment

126 erythroid cells, UNC0638 and EHMT1 or EHMT2 short hairpin RNA-mediated knockdown significantly incre

127 Here we use short hairpin RNA-mediated knockdown to survey the funct

128 Using HCC cell lines, we found that short hairpin RNA-mediated macroH2A1 knockdown induces a

129 the single cell level in MEPs and found that short hairpin RNA-mediated MYB knockdown promoted commit

130 Short hairpin RNA-mediated S100A4 silencing in 231BR-EGF

131 By interrogating data from a large-scale short hairpin RNA-mediated screen across 390 cancer cell

132 Short hairpin RNA-mediated silencing identified TBX5 as

133 that reducing nuclear lamin B1 expression by short hairpin RNA-mediated silencing in cancer cell line

134 Short hairpin RNA-mediated silencing of flotillins in hu

135 a ligand and inhibitor or through lentiviral short hairpin RNA-mediated TGFBR2-specific knockdown.

136 Short hairpin RNA-mediated Vps35 knockdown revealed that

137 Inhibition of SK2 by SK2- specific short hairpin RNA or ABC294640 (a SK2 specific inhibitor

138 TLR2 short hairpin RNA or anti-TLR2 or anti-lipophosphoglycan

139 re evaluated in various cell-based models by short hairpin RNA or inhibition by cabozantinib, the mul

140 combination of STAT3- and C/EBPbeta-specific short hairpin RNA or miR-142-3p confirmed the importance

141 Treatment of WT1mut AML cells with short hairpin RNA or pharmacologic PRC2/enhancer of zest

142 ASPH knockdown or knockout was achieved by short hairpin RNAs or the CRISPR/Cas9 system, respective

143 otion, and suppression of this expression by short-hairpin RNAs or a loss-of-function allele impairs

144 proteins were reduced in Caco-2 cells using short-hairpin RNAs or proteins were inhibited pharmacolo

145 lines (NE3 and NE083), and other cells with short hairpin RNAs, or by genome engineering.

146 demonstrated that N-WASP down-regulation by short hairpin RNA prevented TGF-beta1-mediated disruptio

147 MSI-1 levels, whereas silencing of NOTCH3 by short hairpin RNA reduced MSI-1 levels in both colorecta

148 SET-DeltaSET mutant and knockdown of ESET by short hairpin RNA reduced trimethylation of UBF and resu

149 Depletion of IBTKalpha by short hairpin RNA reduced viability of cultured cells co

150 Knockdown of microRNA-3151 (miR-3151) with short hairpin RNAs reduces cell proliferation and increa

151 Silencing of C5aR2 using lentiviral short hairpin RNA rendered the cells unresponsive to C5a

152 ed TH activity whereas knockdown of Hsc70 by short hairpin RNA resulted in decreased TH activity and

153 Compared with controls, depleting Dsg1 via short hairpin RNA resulted in further reduction of Dsc1

154 ckdown of VTA CTR via adeno-associated virus short hairpin RNA resulted in hyperphagia and exacerbate

155 ncreased by Hrd-1, and knockdown of Hrd-1 by short hairpin RNA resulted in increased abundance in tom

156 We also show that CTCF depletion by short hairpin RNA results in an increase in major IE (MI

157 Depletion of p21 by short hairpin RNA reversed 15-PGDH-induced inhibition of

158 In a short hairpin RNA screen for genes that affect AKT phosp

159 eed, we developed a high content image-based short hairpin RNA screen monitoring levels of the autoph

160 Using a targeted short hairpin RNA screen of BCL-2 family members, we ide

161 ponse of B-ALL to GCs with a next-generation short hairpin RNA screen to identify GC-regulated "effec

162 In this study, we performed a genome-scale short hairpin RNA screen to identify mediators of predni

163 , we use a high-content confocal image-based short hairpin RNA screen to identify tumour suppressors

164 pe and then validated these through a pooled short hairpin RNA screen.

165 Here, we use a targeted short-hairpin RNA screen in a B-cell lymphoma line to id

166 Using a short hairpin RNA screening, we have identified FBXL5 as

167 etic dependencies, we conducted genome-scale short hairpin RNA screens in 17 AML cell lines and analy

168 RNA [shNT]) and FLG knockdown (FLG knockdown short hairpin RNA [shFLG]) LSEs were identified by means

169 ns from paired control (nontargeting control short hairpin RNA [shNT]) and FLG knockdown (FLG knockdo

170 ocytes with knocked down either SCT or SR by short hairpin RNAs show reduced EV secretion during LPS

171 as expressed from an adenoviral vector and 2 short hairpin RNAs (shRdRp2.4) directed against CVB3 wer

172 fficiently delivered synergistic DNA CpG and short hairpin RNA (shRNA) adjuvants, as well as tumor-sp

173 Short hairpin RNA (shRNA) against either TopBP1 or Brd4

174 se down-regulation of DDX20 expression using short hairpin RNA (shRNA) amplified ATF3- and NF-kappaB-

175 PLCbeta1 activities were inhibited by STIM1 short hairpin RNA (shRNA) and absent in TRPC1(-/-) cells

176 We compared the ability of short hairpin RNA (shRNA) and CRISPR/Cas9 screens to ide

177 the i-proteasome catalytic subunit PSMB9 by short hairpin RNA (shRNA) decreased the expression of bo

178 erference experiments using lentivirus-based short hairpin RNA (shRNA) delivery.

179 We show that short hairpin RNA (shRNA) depletion of TET2 results in a

180 , AG1024 and picropodophyllin (PPP), or with short hairpin RNA (shRNA) directed against IGF1R selecti

181 These interventions, or short hairpin RNA (shRNA) directly targeting SQSTM1/p62,

182 Cells were transfected with DBR1 short hairpin RNA (shRNA) followed 48 h later by infecti

183 here, we report that depletion of EYA1 using short hairpin RNA (shRNA) in breast cancer cells destabi

184 Here using in utero electroporation of NDE1 short hairpin RNA (shRNA) in embryonic rat brains, we ob

185 ited by TRPC1 and STIM1 antibodies and STIM1 short hairpin RNA (shRNA) in wild-type VSMCs, and was ab

186 wn of human LIM domain kinase 1 (LIMK1) with short hairpin RNA (shRNA) inhibits HIV infection, no spe

187 0 but not that of ADAM17, as demonstrated by short hairpin RNA (shRNA) knockdown of furin, and promot

188 r the soluble IFN decoy receptor B18R nor by short hairpin RNA (shRNA) knockdown of mitochondrial ant

189 Previous studies showed that short hairpin RNA (shRNA) knockdown of the RNA lariat de

190 Furthermore, short hairpin RNA (shRNA) knockdown of Yap1 expression i

191 In all responsive cell lines, cGAS/STING short hairpin RNA (shRNA) knockdown resulted in a loss o

192 viral replication compartments; furthermore, short hairpin RNA (shRNA) knockdown shows that several,

193 Short hairpin RNA (shRNA) lentiviral vectors targeting T

194 (MDA-MB-435S and SK-MEL-28) cell lines using short hairpin RNA (shRNA) lentiviral vectors.

195 To do this, we analyzed gene trap and short hairpin RNA (shRNA) libraries in AZ-521 human gast

196 he MLL-AF9 fusion oncogene and an epigenetic short hairpin RNA (shRNA) library to screen for novel po

197 Using short hairpin RNA (shRNA) methods, we observed that the

198 ted viral vector containing either the SGLT1 short hairpin RNA (shRNA) or a scrambled RNA sequence.

199 genes were either silenced using lentiviral short hairpin RNA (shRNA) or functionally ablated using

200 Lentivirus-expressed TLR1-short hairpin RNA (shRNA) or TLR2-shRNA administration r

201 iral vector expressing mutant Krt75-specific short hairpin RNA (shRNA) persistently suppressed this p

202 of YAP binding to MT or silencing of YAP via short hairpin RNA (shRNA) reduced MT transformation, sug

203 therapeutic targets in TNBC, we performed a short hairpin RNA (shRNA) screen for protein kinases com

204 We devised an in vivo pooled short hairpin RNA (shRNA) screen in which shRNAs targeti

205 Through a short hairpin RNA (shRNA) screening, we identified singl

206 Knockdown of endogenous NFAT3 expression by short hairpin RNA (shRNA) significantly inhibited tumor

207 Here we show that both targeted mutation and short hairpin RNA (shRNA) silencing of CD24 retard the g

208 Both PLC-gamma1-specific inhibitor and short hairpin RNA (shRNA) strongly suppress the replicat

209 Using a short hairpin RNA (shRNA) system, we show that loss of B

210 th inducible promoters and cognate-inducible short hairpin RNA (shRNA) targeted against the reporter

211 ntation experiments with lentiviral-infected short hairpin RNA (shRNA) targeting all FIR variants as

212 deno-associated virus-mediated delivery of a short hairpin RNA (shRNA) targeting the endogenous rat S

213 etion of the essential PRC2 protein Suz12 by short hairpin RNA (shRNA) technology enhanced the RA-ass

214 re we utilize a mouse model of inducible p53 short hairpin RNA (shRNA) to show that temporarily block

215 Knockdown of Hrs by short hairpin RNA (shRNA) transduction resulted in signi

216 crophages that had been depleted of Rab1B by short hairpin RNA (shRNA) treatment, indicating that T2S

217 ls revealed that downregulation of SLPI with short hairpin RNA (shRNA) upregulated nuclear factor kap

218 This study utilized novel lentiviral short hairpin RNA (shRNA) vectors to target expression o

219 Specific inhibitors and short hairpin RNA (shRNA) were employed to demonstrate r

220 ably express the K-Ras oncogene and obscurin short hairpin RNA (shRNA), but not scramble control shRN

221 nflammasome-induced pathway was inhibited by short hairpin RNA (shRNA), HBoV1-induced cell death drop

222 Using an unbiased genome-scale screen with short hairpin RNA (shRNA), we identified the receptor TR

223 Using a conditional, short hairpin RNA (shRNA)-based knockdown system in the

224 Acute short hairpin RNA (shRNA)-mediated depletion of c-MYC re

225 Lentiviral short hairpin RNA (shRNA)-mediated depletion of Ror2 in

226 A permanent reduction of DNMT1 protein using short hairpin RNA (shRNA)-mediated DNMT1 silencing rende

227 function, we performed parallel genome-scale short hairpin RNA (shRNA)-mediated gene knockdowns in KI

228 Lentiviral short hairpin RNA (shRNA)-mediated genetic screening is

229 that the acute and selective Fgf14-targeted short hairpin RNA (shRNA)-mediated in vivo "knock-down"

230 Short hairpin RNA (shRNA)-mediated knockdown of EN1 trig

231 Short hairpin RNA (shRNA)-mediated knockdown of LC3 prev

232 We demonstrate that short hairpin RNA (shRNA)-mediated knockdown of Megf10,

233 Furthermore, short hairpin RNA (shRNA)-mediated knockdown of the p75N

234 -) or Foxp3-mRFP/cd69(-/-) reporter mice and short hairpin RNA (shRNA)-mediated silencing and miR-155

235 Using short hairpin RNA (shRNA)-mediated suppression of NRP1,

236 hat are prone to Gravin depletion and Gravin short hairpin RNA (shRNA)-treated cells, an increase in

237 Acute gene inactivation using short hairpin RNA (shRNA, knockdown) in developing brain

238 henylglycine t-butyl ester (DAPT), or Notch1 short hairpin RNAs (shRNA) remarkably reduced the cispla

239 Short, hairpin RNA (shRNA) silencing lentivirus targetin

240 In parallel, 362 short-hairpin RNA (shRNA) constructs against 276 unique

241 We also constructed a short-hairpin RNA (shRNA) for silencing fatty-acid-bindi

242 Knockdown of endogenous MEF2D with a short-hairpin RNA (shRNA) increases sensitivity to etopo

243 Using a barcoded lentivirus-based pooled short-hairpin RNA (shRNA) library combined with next gen

244 Indeed, short-hairpin RNA (shRNA)-mediated knockdown of p62 impa

245 compared to other RNAi-based methods such as short-hairpin RNAs (shRNA).

246 ansfer (adeno-associated viral expression of short hairpin RNA [shRNA]) approaches were used to inhib

247 nsduction system to deliver microRNA-adapted short hairpin RNAs (shRNAmirs) into the parasite to sile

248 Systematic knockdown of all six genes using short hairpin RNAs (shRNAs) and follow-up functional stu

249 Short hairpin RNAs (shRNAs) are effective in generating

250 plex, including CUL4B, DDB1 or DCAF11, using short hairpin RNAs (shRNAs) attenuated the ubiquitinatio

251 ae (baker's yeast) was engineered to produce short hairpin RNAs (shRNAs) corresponding to the Aedes a

252 A screen using pooled short hairpin RNAs (shRNAs) identified the ATP-buffering

253 oblast-specific lentiviral delivery of FOSL1 short hairpin RNAs (shRNAs) provided in vivo validation

254 ines for doxycycline-inducible expression of short hairpin RNAs (shRNAs) targeting the PI4P effector,

255 ens using short interfering RNAs (siRNAs) or short hairpin RNAs (shRNAs), as well as for Drosophila s

256 Thus, similar to manmade RNAP III-generated short hairpin RNAs (shRNAs), the BLV pre-miRNAs are init

257 e gene expression consequences of expressing short hairpin RNAs (shRNAs).

258 using tetraspanin antibodies and tetraspanin short hairpin RNAs (shRNAs).

259 classifier to predict potent microRNA-based short hairpin RNAs (shRNAs).

260 either RAGE overexpression or knockdown with short hairpin RNAs (shRNAs).

261 uced neurospheres with lentiviruses encoding short-hairpin RNAs (shRNAs) against MCT4, resulting in g

262 n of S100A8 and S100A9 in cancer cells using short hairpin RNA significantly diminished migration and

263 g endosomal membranes, and NHE5 knockdown by short hairpin RNA significantly elevates pH of TfR-posit

264 Dominant negative constructs and short hairpin RNA silencing demonstrated a role for MYO5

265 Short hairpin RNA silencing of kindlin-2, but not c-Src,

266 engineered to carry short interfering RNA or short hairpin RNA specific to oncogenic Kras(G12D), a co

267 A lentiviral vector encoding short-hairpin RNA specific for hCtr1 (Lenti-hCtr1-shRNA)

268 cally inhibited its liver expression using a short hairpin RNA strategy in mice.

269 Using a short hairpin RNA strategy, we demonstrate here that the

270 d SPOP mutants or upon knockdown of SPOP via short-hairpin-RNA, suggesting that SPOP inactivation dir

271 Using PC12 cells stably transfected with short-hairpin RNA targeted to synaptotagmin I, an exocyt

272 el, subcutaneous injection of SK5 cells with short hairpin RNA-targeted downregulation of mGlu1 recep

273 A short hairpin RNA targeting AnxA2 (shAnxA2) was formulat

274 ably transduced PC12 cells with an inducible short hairpin RNA targeting clathrin heavy chain, result

275 Adenovirus expressing short hairpin RNA targeting fibroblast growth factor 21

276 Short hairpin RNA targeting of TMEM88 during hESC cardia

277 ma3e using adeno-associated virus 2 carrying short hairpin RNA targeting Sema3e promoted disoriented

278 used a virally mediated knockdown strategy (short hairpin RNA targeting the glucocorticoid receptor

279 Conditionally expressed short hairpin RNA targeting these lncRNAs in castration-

280 nses to IL-17 using a tetracycline inducible short hairpin RNA targeting TRAF3IP2.

281 ion of galectin-3 in human melanocytes using short hairpin RNA technology resulted in the reduction o

282 -associated virus (AAV-GLP-1R) that utilizes short hairpin RNA to chronically knock down GLP-1 recept

283 ere transfected with histidine decarboxylase short hairpin RNA to decrease histamine secretion and su

284 By using short hairpin RNA to deplete proteins involved in specif

285 e downstream effects could be reversed using short hairpin RNA to KISS1 or PGC1alpha, these data appe

286 Finally, using short hairpin RNA to knock down CD29 and/or CD49f in met

287 graft were pretreated with HDAC inhibitor or short hairpin RNA to knock down expression of HDAC4 and

288 eotactically injected viral vectors encoding short hairpin RNA to knock down expression of the essent

289 We used knockout mice and short hairpin RNA to knock down guanine nucleotide bindi

290 on had been silenced by stable expression of short hairpin RNA to target DST.

291 each candidate protein in HepG2 cells using short hairpin RNAs to determine their effect on LDL upta

292 xpression of GPA, GPB, or GPC via lentiviral short hairpin RNA transduction of erythroid progenitor c

293 tatus of these cells compared with nontarget short hairpin RNA-treated cells.

294 Knockdown of RhoE by short-hairpin RNA using a lentiviral approach led to inc

295 Furthermore, short hairpin RNA vectors and small molecule inhibitors

296 which DISC1 function was reduced in vivo by short hairpin RNA viral knockdown or in vitro by dialysi

297 To investigate LSP1 function in HCC, short hairpin RNA was utilized to stably knock down LSP1

298 However, by using MMP2 short hairpin RNA, we demonstrate that the alphavbeta6 e

299 Using short hairpin RNA, we knocked down spartin in RAW264.7 c

300 were individually silenced using lentiviral short hairpin RNAs, which lead to a decrease (>/=80%) of