ライフサイエンスコーパス: short-lived

1 with PCNSL; however, responses were usually short lived.

2 to be long lived while mRNAs tend to be more short lived.

3 triatal transmissions, and these effects are short lived.

4 iotic treatment, this response appears to be short lived.

5 d and stable, whereas COX-2 is inducible and short lived.

6 marrow, PCs in the gut have been considered short lived.

7 eveal that 20% of spines lack PSD-95 and are short lived.

8 ncer chest wall metastases but responses are short-lived.

9 ate-limiting and metabolic intermediates are short-lived.

10 this behavior have typically shown it to be short-lived.

11 y, however, this tumor response is generally short-lived.

12 the radiative effect of volcanic forcings is short-lived.

13 cannot be measured in vivo because they are short-lived.

14 ative effects on reproductive fitness can be short-lived.

15 lying that magnetic activity would have been short-lived.

16 Visual symptoms were usually mild and short-lived.

17 (e.g. a specific ubiquitin ligase) is itself short-lived.

18 reme events and find that they are generally short-lived.

19 t relatively poor B-cell responses which are short-lived.

20 d titer increases were only about 2-fold and short-lived.

21 g among auditory cortex neurons was weak and short-lived.

22 cted that this species should be kinetically short-lived.

23 nefficient polarization in water, relatively short-lived (1)H-polarization, and relatively limited su

24 to our conclusion is the demonstration that short-lived (10)Be can be readily synthesized in such su

25 We use the reconstructed concentrations of short-lived (26)Al in chondrules to constrain the timing

26 The short-lived (26)Al radionuclide is thought to have been

27 prohibitive to clinical translation, but the short-lived (51)Mn (t1/2: 46 min, beta(+): 97%) represen

28 mouse embryonic fibroblasts, we observe that short-lived (~8 s) Pol II clusters correlate with basal

29 of sensitized emission from an intrinsically short-lived acceptor.

30 hat ubiquitin-like processing of Sde2 into a short-lived activated form may function as a checkpoint

31 pecific proteases Ubp5 and Ubp15 generates a short-lived activated Sde2-C fragment with an N-terminal

32 new approaches, such as the use of the very short-lived African killifish (Harel et al.), are bridgi

33 pendently provide a reference genome for the short-lived African turquoise killifish, establishing it

34 ssemble a reference genome for the naturally short-lived African turquoise killifish, providing a uni

35 formation can be restored by the addition of short-lived, Ag-pulsed APC at this checkpoint.

36 n sensitive, immunologically compromised and short-lived, all phenotypes associated with compromised

37 d also hold for other high-affinity mAbs and short-lived alpha-emitters.

38 We describe novel short lived and cycling patterns of gene expression and

39 n the glomerular capillaries, where they are short lived and make a modest contribution to glomerular

40 The spikes were short-lived and accounted for less than 10% of annual ha

41 Mass extinction events are short-lived and characterized by catastrophic biosphere

42 ry stage of community convergence was itself short-lived and independent of founders' personality; al

43 involving IR(-) NK cells were generally more short-lived and IR(-) NK cells did not become activated

44 ligodendrocyte glycoprotein-specific Abs and short-lived and long-lived autoantibody-secreting cells

45 Using the WorMotel, we find that short-lived and long-lived strains exhibit patterns of b

46 al studies indicate that these exceptionally short-lived and low-abundance species form Watson-Crick-

47 t antibody kinetics in wildlife hosts can be short-lived and produce patterns that are repeatable acr

48 ells expressing these tegumental factors are short-lived and rapidly turned over.

49 ctions, and in particular of the role of the short-lived and reactive intermediate states involved, w

50 Junctions can be relatively short-lived and simple structures, forming and dissolvin

51 Neutrophils are short-lived and spontaneously die by apoptosis.

52 its protein coat, but this altered state is short-lived and thus poorly understood.

53 arget and a permissive environment, they are short-lived and thus require supplemental strategies suc

54 netics may be suitable for labeling with the short-lived and widely clinically available radiometal (

55 Side effects were short-lived, and clinical improvement was maintained for

56 ders diploid partial apomicts evolutionarily short-lived, and results in fixation of triploid apomict

57 s than after RV144, but these responses were short-lived, and their magnitude did not increase with s

58 We now demonstrate that the presence of a short-lived anionic flavin semiquinone (ASQ) is not suff

59 CDK9 mediated transcriptional regulation of short-lived antiapoptotic proteins is critical for the s

60 ard the rapid induction of strongly induced, short-lived antibodies of limited efficacy.

61 colysis and other metabolic pathways to form short-lived antigens.

62 fs during exciton deactivation, but they are short-lived ( approximately 100 fs) and quickly transfer

63 In addition, various short-lived aqueous species are also induced, regardless

64 ttachment on indole-3-acetic acid1 (IAA1), a short-lived Arabidopsis (Arabidopsis thaliana) Auxin/ind

65 rovide new insight into the poorly known and short-lived Arctic forest community of the Early Eocene

66 ated by these synthetic complexes are not as short-lived as those obtained from heme-based oxidants a

67 larger, landslide deposits is exceptionally short-lived, as they are rapidly reworked.

68 We have found indication of short-lived ASCs in the local lymphoid tissue, further e

69 DV-specific ASCs, indicating the presence of short-lived ASCs, a hallmark of a T-independent 2 (TI-2)

70 The frequent, but short-lived, associations of bison with different spatia

71 on from the triplet excited state and a very short-lived biradical intermediate, which does not accum

72 bacterial community, defined initially by a short-lived bloom of Methylophaga (putative oil degrader

73 This short-lived burst in kinase activity links development w

74 phosphodiesterase 4) promoted degradation of short-lived (but not long-lived) cell proteins generally

75 Interestingly, transgenic IL-12 was short-lived, but endogenous IL-12 expression was induced

76 s with stroma cells as indicated by sporadic short-lived calcium spikes.

77 to the incoherent excitation transfer to the short-lived carotenoid excited states.

78 since most HIV-1 target cells are activated, short-lived CD4 T cells.

79 We found that short-lived channel closures during channel openings rep

80 Rather, a short-lived CheR binding interaction appears to promote

81 e protein occupancy, especially for TFs with short-lived chromatin binding.

82 Understanding the role of short-lived climate forcers such as black carbon (BC) at

83 glacial timescales, but their sensitivity to short-lived climate perturbations is largely unknown.

84 , the super pollutant (SP) lever to mitigate short-lived climate pollutants, and the carbon extractio

85 -time constant (taucf ), which describes the short-lived closures that interrupt open bursts, was gre

86 udies, we observed that Pol II clusters were short-lived (cluster lifetime ~8 s) in living cells.

87 was shown to be quite broad when applied to short-lived clusters found in molecular-beam experiments

88 rs of ANCL CSPalpha mutants were shown to be short-lived compared with wild-type CSPalpha, suggesting

89 and the N-terminal domain formed a tight but short lived complex, characterized by fast on- and off-r

90 A relatively short-lived component (0.3-1.7 mus) accounts for only 3-

91 pants aged 5-17 months, the half-life of the short-lived component of the antibody response was 45 da

92 d that anchor-matrix bonds that are weak and short-lived confer superior trapping potency, contrary t

93 rayed states are metastable intermediates or short-lived configurations during the full dissociation

94 er half-lives in indolent cases, and weaker, short-lived contacts mediating the aggressive ones.

95 action resulted in the formation of numerous short-lived cortex-bound alphaABD clusters.

96 one marrow LLPCs compared with their splenic short-lived counterparts (SLPCs).

97 yruvate-dependent respiration, whereas their short-lived counterparts could not.

98 (NK) cells have historically been considered short-lived cytolytic cells that can rapidly respond aga

99 g-lived daf-2 mutant but are enhanced in the short-lived daf-16 mutant.

100 patterns in mating behaviour in adults of a short-lived damselfly, Coenagrion puella and the implica

101 ong-lived stem cells and frequently-dividing short-lived daughter transit cells.

102 Short-lived diradical species were observed in the oxyge

103 onal transport of cytosolic cargos, based on short-lived direct interactions of cargo with a highly p

104 Chemotherapy and targeted therapies offer short-lived disease control.

105 he metallic melt, the resultant ULVZs may be short-lived domains that are replenished or regenerated

106 The ability to exploit local and short-lived dSi hotspots using a specific search behavio

107 ases where T cell immunity is ineffective or short-lived due to PD-1-mediated signaling.

108 However, the adjuvant activity of IL-12 is short-lived due to regulatory T cell (Treg) reinfiltrati

109 are highly effective but responses are often short-lived due to the emergence of drug-resistant tumor

110 iate into two main populations of effectors: short-lived effector cells (SLECs) and memory precursor

111 ector cells (MPECs), which are distinct from short-lived effector cells that provide acute protection

112 ic CD8(+) T cells into CD127(low)KLRG1(high) short-lived effector cells, preferentially expanding the

113 nce the response toward long-lived memory or short-lived effector cells.

114 bisulfite sequencing of primary human naive, short-lived effector memory (TEM), and longer-lived cent

115 the gene encoding FOXO1, T cells revert to a short-lived effector phenotype, exhibit reduced viabilit

116 +)YFP(+)GFP(+) T cells generally exhibited a short-lived effector rather than effector memory T cell

117 Most of these are short-lived effector T cells (SLECs) that die after clea

118 eonatal CD8(+) T cells preferentially become short-lived effectors and adult CD8(+) T cells selective

119 killer (NK) cells have long been considered short-lived effectors of innate immunity.

120 ment the gammadeltaT-17 response in favor of short-lived effectors with limited plasticity, particula

121 Control and mechanistic studies suggest a short-lived electrophilic intermediate, which is likely

122 lted in only a mild and transient rash and a short-lived elevation of the body temperature.

123 d luminescence of Mn(2+) with the relatively short-lived emission of lanthanides.

124 We conclude that the highly proliferative, short-lived enterocyte precursors serve as a large reser

125 Alternatively, geographic variants might be short-lived entities with rates of formation that are un

126 A) in the MARCH6 CTE stabilized the normally short lived enzyme to the same degree as a catalytically

127 e focus of anoxia at these times, as well as short-lived episodes of oxia that supported diverse biot

128 Most short-lived eukaryotic proteins are degraded by the prot

129 model of the nanopore system to characterize short-lived events that do not reach their steady-state

130 phorous triamide intermediates are typically short lived, evolving with elimination of the N-borylami

131 conformational exchange dynamics present in short-lived excited protein states, such as those transi

132 occurs when the final state coincides with a short-lived excited state.

133 fers a strategy to circumvent the inherently short-lived excited states of 3d metal complexes for the

134 asts and plasma cells (PCs) by enhancing the short-lived extrafollicular response and reducing the po

135 CR2-dependent manner, where they mature into short-lived F4/80(lo)MHCII(+) cells that act, in part, a

136 on but drives effector CD8(+) T cells into a short-lived fate, whereas IFN-gamma signaling impairs th

137 ing competitive plants to divert carbon from short-lived fine roots to long-lived woody biomass.

138 g genes are under positive selection in this short-lived fish and long-lived species, raising the int

139 d, reflecting an input from the decay of the short-lived fission products (95)Zr and (97)Zr.

140 the Zn(2+) ion, forming a marginally stable, short-lived folded Abeta40 species.

141 the addition/head-to-tail polymerization of short-lived free phosphinoborane monomers, R(1)R(2)P-BH2

142 Here we observe such a transition in a short-lived gas of exciton-polaritons, bosonic light-mat

143 re stable or decreasing due to reductions in short-lived gases or net radiative forcing.

144 ally isolated lineages, while the latter had short-lived geographically diffuse lineages.

145 analyses of short-lived Mdh2 as a target of short-lived Gid4, we illustrate the advantages of PRT ov

146 alysis of myeloid progenitors, which produce short-lived granulocytes, demonstrate that these are der

147 We show that short-lived greenhouse gases contribute to sea-level ris

148 All other adverse events were mild: short-lived headaches coincident with seasonal allergies

149 roxy oxygens, consistent with synthesis of a short-lived hemiacetal intermediate that breaks down spo

150 dox catalysis processes and particularly the short-lived highly reactive radical intermediate BrO2(*)

151 mited to the early Eocene, especially during short-lived hyperthermals.

152 Current vaccines against CBPP induce short-lived immunity and can cause severe postvaccine re

153 recurs frequently and establishes a weak and short-lived immunity.

154 d, suggesting that elevational generalism is short-lived in geological time?

155 results suggest that Cu and Cuox NPs will be short-lived in the environment unless dissolution is hin

156 in the electronic excited-state, undergoes a short-lived increase in acidity.

157 Sld2-pre-RC complex, but the complex is only short-lived, indicating an anti-cooperative mechanism.

158 This is not the case for a neutrophil, a short-lived innate immune cell with an unusual multilobu

159 ells were previously considered to represent short-lived, innate lymphocytes.

160 We observed predominantly short-lived interactions in a free-ranging tortoise popu

161 ng NTF2 binding, which is dominated by weak, short-lived interactions that derive from steric hindran

162 unfolded OMP makes, on average, hundreds of short-lived interactions with chaperones before folding

163 the presence and translocation mechanisms of short-lived intermediate bound states that are likely to

164 hree conformations: resting, activated and a short-lived intermediate state.

165 demonstrate that sulfenic acid is a crucial short-lived intermediate that dictates the protein's fat

166 A very short-lived intermediate was observed to start the G4 fo

167 g regulate the transition of bonds among the short-lived, intermediate, and long-lived state.

168 rstanding on the structure and properties of short-lived intermediates but also with the aim to creat

169 New syntheses with very short-lived intermediates have been enabled by sub-milli

170 e determination of reactivity parameters for short-lived intermediates provides an indispensable tool

171 tructural information about the proposed and short-lived intermediates.

172 In contrast, application of short-lived intraventricular pressure surges neither tri

173 Mn(2+) upconversion emission and relatively short-lived lanthanide upconversion emission in a partic

174 ng-lived leaves (i.e., evergreen) to low-LMA/short-lived leaves (i.e., deciduous).

175 adiocarbon-enriched signals to represent two short-lived (less than 500 years) "overshoot" events, wi

176 Neutrophils are exceptionally short-lived leukocytes, yet it remains unclear whether t

177 For instance, in our short-lived life history, individual variability has lar

178 ely populated ( approximately 0.02-0.4%) and short-lived (lifetimes approximately 0.2-2.5 ms) Hoogste

179 that RNAs exist in dynamic equilibrium with short-lived low-abundance 'excited states' that form by

180 A duplexes exist in dynamic equilibrium with short-lived, low-populated Watson-Crick-like mispairs th

181 d off-target binding events are, on average, short-lived (<1 second).

182 esterol and its presumed promotion of a very short-lived (<50 ms) lipid stalk intermediate is the mai

183 Through analyses of short-lived Mdh2 as a target of short-lived Gid4, we ill

184 d rule pathway, whose substrates include the short-lived Mdh2 malate dehydrogenase.

185 Neutrophils are critical and short-lived mediators of innate immunity that require co

186 pectroscopy measurements, and that even if a short-lived, metastable species does exist at the vacuum

187 -metathesis by-products-and the formation of short-lived methylidene complexes.

188 of times between life-history events, using short-lived midge species as an example.

189 ric dissolved organic matter ((3)CDOM*) is a short-lived mixture of excited-state species that plays

190 crobes to supply, accumulate, and regenerate short-lived Mn(3+) species in the litter layer.

191 ialization include reliance on findings from short-lived model organisms, poor biological understandi

192 The long sought-after, intrinsically short-lived molecule ethylenedione (OCCO) was observed a

193 proteins allowing for the differentiation of short-lived monocytes into long-lived macrophages, a key

194 The presence of viral uracils in short-lived monocytes suggests their recent infection th

195 As a result, short-lived mRNAs were imaged throughout their complete

196 However, for short-lived mRNAs, the tight binding of the MS2 coat pro

197 ammatory disorders characterized by aberrant short-lived myeloid cell lifespan.

198 at the phonon gap signifies the formation of short-lived nanometre-scale lipid clusters and transient

199 tance of developing tools capable of probing short-lived nanoscale species at the single-particle lev

200 We propose that the resulting short-lived nature of CRISPR-dependent bacteria-virus co

201 Due to the highly reactive and short-lived nature of ROS and RNS, combined with limitat

202 This enabled the identification of a short-lived Ni(I) species aided by time-dependent densit

203 cies increases with pump beam intensity, and short-lived nitrogen emission originating from the ambie

204 resolution enabled detection and analysis of short-lived non-coding RNAs as well as intron-containing

205 Short-lived, nonequilibrium nanocrystals are observed, s

206 adation of long-lived cell proteins, but not short-lived ones, by stimulating proteolysis by proteaso

207 to the RNAP cleft and opening 13bp to form a short-lived open intermediate (I2).

208 t it is equivocal whether the improvement is short-lived or long-lasting, and additionally what accou

209 ng but can be difficult to characterize when short-lived or not significantly populated.

210 As a result, many deployments become short-lived or underutilized, and many new scientific de

211 at formation of the crystalloid-a unique and short-lived organelle of the Plasmodium ookinete and ooc

212 or on, the surface were suggested to explain short-lived outbursts seen near sunrise on comet 9P/Temp

213 he presence of a noncognate substrate but is short-lived owing to lack of optimal complementarity bet

214 Peroxynitrite is a short-lived oxidant species that is a potent inducer of

215 Sulfate radical (SO4(*-)) is a strong, short-lived oxidant that is produced when persulfate (S2

216 er of singlet oxygen ((1)O2), a reactive and short-lived oxygen species, has until now been unknown.

217 ly selectively at the CH3O group to generate short-lived oxymethyllithiums.

218 d during malaria, a disease characterized by short-lived, parasite-specific Ab responses.

219 This coupled excitable system leads to short-lived patches of activated Ras and associated F-ac

220 by supporting the survival of LLPC, but not short-lived PC (SLPC).

221 ntibody responses may be sustained solely by short-lived PCs with repopulation from clonally related

222 all treatments and taxa to take advantage of short-lived periods of high moisture availability, when

223 ot much information has been obtained on the short lived persistent radical species.

224 Short-lived phasic electrical stimulation of the region

225 ive organisms across various habitats - from short-lived phytoplankton to long-lived corals - in resp

226 n assay; it is specifically expressed in the short-lived placenta at the level of the syncytial feto-

227 fast-slow continuum, including fast-growing, short-lived plant species at one end and slow-growing, l

228 The extrafollicular pathway gives rise to short-lived plasma cells (PCs) that can rapidly secrete

229 LLPCs took up more glucose than did short-lived plasma cells (SLPCs) in vivo, and this gluco

230 activation, proliferation, and generation of short-lived plasma cells that reside in extrafollicular

231 low levels of Ig and are mostly found among short-lived plasmablasts.

232 ronous concerted mechanism with a relatively short-lived polar transition state (average lifetime = 5

233 phenomena arise from a confluence of rapid, short-lived positive signals driven by the protein tyros

234 boxylic acids and amide derivatives with the short-lived positron emitter carbon-11 (t1/2 = 20.4 min)

235 on of synthetic biomolecules often result in short-lived presentations, or require genetic manipulati

236 long evolutionary and historical path, from short-lived primate ancestors to contemporary Japan, Swe

237 more responsive to IFN-gamma than cells from short-lived primate species, and this increase in IFN-ga

238 Over time, they become short-lived progenitors, generating differentiating daug

239 ent study, we have discovered that PDK4 is a short lived protein (t(1/2) approximately 1 h) and is sp

240 Steady-state level of this short-lived protein is tightly controlled by multiple me

241 transcription factor MATalpha2 (alpha2) is a short-lived protein known to be ubiquitylated by two dis

242 fective ribosomal products (DRiPs) and other short-lived proteins (SLiPs) into autophagosomes via seq

243 The proteasome degrades many short-lived proteins that are labeled with an ubiquitin

244 ed proteins to become stabilized relative to short-lived proteins, leading to alterations in the abun

245 s suggest that the reaction proceeds through short-lived radical intermediates with F-transfer mediat

246 electrospray emitter, allows us to detect a short-lived radical metabolite of chlorpromazine which i

247 of chemical reactions are initiated by these short-lived radical species in solution.

248 c aerosols (SOA) were investigated using the short-lived radioactive tracer (13)N in flow-reactor stu

249 nontarget tissues, and facilitate the use of short-lived radionuclides that would otherwise be incomp

250 supernovae also produce telltale patterns of short-lived radionuclides, which would be preserved toda

251 OM) can sensitize the formation of different short-lived reactive intermediates (RIs), including hydr

252 The short-lived reactive oxygen species (ROS) and reactive n

253 The short-lived reactive species in CAP may activate cells i

254 stabilize and assist the characterization of short-lived reactive species such as cyclobutadiene or o

255 eport on LSD in 1950, psychedelics enjoyed a short-lived relationship with psychology and psychiatry.

256 irth and subsequent growth) and mortality of short-lived, relatively shade-intolerant tree species.

257 rhyolitic eruption in New Zealand reflected short-lived residence at magmatic temperatures interleav

258 lived response) and immunoglobulin G3 (IgG3; short-lived response indicating more recent infection) f

259 the lack of abortive RNA in initiation from short-lived ribosomal promoter OCs are well described by

260 O2 play a crucial role for the production of short-lived RNS.

261 reactions: NO3 is an important precursor for short-lived ROS, and in turn OH, O2(-) and HO2 play a cr

262 eodymium-142 ((142)Nd), the decay product of short-lived samarium-146 ((146)Sm).

263 ward communities dominated by bloom-forming, short-lived seaweeds.

264 hitherto only been proposed tentatively as a short-lived species generated in electrochemical or micr

265 thesis, but the presence and impact of these short-lived species on semiconductor nanowire growth are

266 eneration time effect" should be stronger in short-lived species, explaining why the generation time

267 The identification of short-lived species, likely active species, is often hin

268 atures through extended signal averaging for short-lived species.

269 lation period T, enhances the sensitivity to short-lived species.

270 photocarriers manifest themselves through a short-lived spike in terahertz photoconductivity that de

271 onventional models, VB-HMM revealed multiple short-lived states characterized by rapid switching and

272 time scales of reversibility of TSLR due to short-lived substances provides insights into physical p

273 This suggests that, at least for the short-lived superoxide species, light-independent proces

274 hermal half-lives of their (Z)-isomers, from short-lived T-type to thermally stable P-type derivative

275 d MDC peaked early (Tmax=15-45 min) and were short lived (t1/2=60-90 min), while HHMC and HMMC peaked

276 Large numbers of short-lived Teff cells were continuously produced via a

277 eased CD8(+) T cell differentiation toward a short-lived, terminal effector fate, as evidenced by inc

278 star by a supermassive black hole leads to a short-lived thermal flare.

279 r and anxiety; both show phasic responses to short-lived threat; and both show heightened activity du

280 er possibility, that the connections are too short-lived to be captured by microscopy during a normal

281 estern banded geckos, which are abundant and short-lived, to chuckwallas and desert iguanas, which ar

282 quantification of myocardial blood flow with short-lived tracers, such as (82)Rb-chloride, requires a

283 The p53 tumour suppressor protein is a short-lived transcription factor that can inhibit the gr

284 ransitions for these excited states assign a short-lived transient signal to the spectroscopic signat

285 Once activated, SCs typically give rise to short-lived transit-amplifying cells (TACs), which then

286 We conclude that, despite being short-lived, transplanted ASCs can accelerate wound-heal

287 Their abrupt nature necessitates a similarly short-lived trigger, and large igneous province magmatis

288 iomarkers that can predict the conversion of short-lived tumor antigen-specific T effector cells into

289 goals and suppresses conflicting maladaptive short-lived urges to balance impulsivity, exploration an

290 ollowed by the accumulation of PI(3)P on the short-lived vacuole.

291 n experimental aging research is the lack of short-lived vertebrate models for genetic studies.

292 lifish (Nothobranchius furzeri), a naturally short-lived vertebrate, we show that the gut microbiota

293 On its own, this moderate, short-lived warming was unlikely to cause widespread dam

294 e-like responses are typically thought of as short-lived, we found that changes persisted for months

295 Among terrestrial species, abundances of a short-lived, winter-spring breeder increased markedly by

296 However, these reducing moieties are short-lived (with a half-life of 1.9 h) and easily oxidi

297 rders in which benefits from shunting may be short-lived, with a consequently unfavorable risk-benefi

298 l in inducing remissions, these are normally short-lived, with median response durations of <1 year.

299 Igalpha tail-truncated B cell population is short-lived, with the HC-deficient cells displaying sign

300 A stepwise mechanism involving short-lived zwitterion intermediates is established.