ライフサイエンスコーパス: shortcoming

1 very, remains an acknowledged but unresolved shortcoming.

2 mmonly used cyclooctynes represent a serious shortcoming.

3 necessary to determine the reasons for this shortcoming.

4 activity-based NP screening to address these shortcomings.

5 hat our findings remain robust despite these shortcomings.

6 esses are available, although each possesses shortcomings.

7 t of numerical cognition that remedies these shortcomings.

8 ular tools that can be used to address these shortcomings.

9 l and transseptal routes, both of which have shortcomings.

10 ation of B-DNA in solution, despite residual shortcomings.

11 developed, while most of them have distinct shortcomings.

12 influence the performance of LFIAs and their shortcomings.

13 tenosis), and most trials had methodological shortcomings.

14 ese by-products would overcome both of these shortcomings.

15 shown that this description has substantial shortcomings.

16 of a generalised model that overcomes these shortcomings.

17 cardiac leads and their associated risks and shortcomings.

18 we present a new method that overcomes these shortcomings.

19 labelling have been developed, each with its shortcomings.

20 However, they have several shortcomings.

21 melt, but these two interpretations have two shortcomings.

22 ssessed, and most studies had methodological shortcomings.

23 induced thrombocytopenia (HIT) has important shortcomings.

24 ear translational potential and have various shortcomings.

25 ne scenario that may partially explain these shortcomings.

26 h modality has its own unique advantages and shortcomings.

27 y between studies and important methodologic shortcomings.

28 considered uncertain because of methodologic shortcomings.

29 nstrate how ATria overcomes several of their shortcomings.

30 echnological aspects as well as benefits and shortcomings.

31 (HSC) ageing is linked to several functional shortcomings.

32 Despite these gains, the ACA has numerous shortcomings.

33 e included, many of which had methodological shortcomings.

34 y, therefore each one has its advantages and shortcomings.

35 ated the impact of SCM due to methodological shortcomings.

36 s (bNAbs) against HIV-1 could overcome these shortcomings.

37 (ts) and halorhodopsin [1-3]), but both have shortcomings [4-9].

38 To address this shortcoming a new, photoredox-Ni dual catalytic strategy

39 While each hypothesis alone has its shortcomings, a synthesis of the two can explain much of

40 followed by freeze drying can overcome this shortcoming and can produce CNC aerogels with minimal st

41 We have also overcome the shortcomings and combined the features of two royalty-fr

42 ies enumerated above will help address these shortcomings and enhance patient care worldwide.

43 d future increases in demand despite several shortcomings and gaps in the current offer.

44 olds significant promise to circumvent these shortcomings and has the additional advantage of potenti

45 dations on how to experimentally address any shortcomings and improve data for persistence and risk a

46 he present article discusses the theoretical shortcomings and misconceptions of this approach to visu

47 Specific shortcomings and potential pit falls in preclinical eval

48 earning methods and suggests reasons for the shortcomings and problems listed above.

49 s from the injured site would abrogate these shortcomings and provide enumerative insights into the r

50 nd large patient cohorts will overcome these shortcomings and provide further insight into the pathog

51 symptoms, but were limited by methodological shortcomings and small sample sizes.

52 with superionic conductivity can avoid those shortcomings and work with a metallic lithium anode, the

53 provide several examples to illustrate this shortcoming, and derive a lower bound on the information

54 ly large internal climate variability, model shortcomings, and because CA lies within a transition zo

55 tion of model results and their assumptions, shortcomings, and errors.

56 n the progress made in higher education, the shortcomings, and how new initiatives hold great promise

57 ommonly used stroke models, their merits and shortcomings, and how these have contributed to translat

58 uid behavior are phenomenological, have many shortcomings, and lack consistent links to elementary po

59 acknowledgement of the study's strengths and shortcomings, and more recent trial data, suggest that a

60 uccessful strategy to date to overcome these shortcomings, and more than 10 PEGylated proteins have b

61 We describe recent highlights as well as shortcomings, and our ideas on the further development o

62 parasite HGT, discussing their merits, their shortcomings, and the multiple lines of evidence needed

63 lectively highlight experimental advantages, shortcomings, and tools of each model organism.

64 s molecular diagnostics and their merits and shortcomings are also discussed in some depth.

65 These shortcomings are attributed to limited structural contro

66 gic behind current classifications and their shortcomings are explored in various examples of lung di

67 The shortcomings are its semiquantitative measurements, lowe

68 However, we show that such shortcomings are not an inherent limitation of approxima

69 Methodological shortcomings are prevalent in preclinical cardiovascular

70 quency domain nonlinear optics overcomes the shortcomings arising from the convolution in conventiona

71 entify important features underlying C-PfCSP shortcomings as a vaccine target.

72 This is an obvious shortcoming, as networks are dynamic, and sometimes not

73 tural development, as well as advantages and shortcomings associated with each method.

74 This paper addresses this shortcoming by considering two significant sources of un

75 Here, we address this shortcoming by demonstrating multiplexed northern blotti

76 t is not high-dimensional, we can avoid this shortcoming by doing an exhaustive search.

77 Here we address this shortcoming by establishing a methodical workflow necess

78 The present review mitigates this shortcoming by hierarchically exploring within an ecotox

79 We address this shortcoming by investigating a series of methylated adam

80 We have attempted to address this shortcoming by producing a dynamic, six-compartmental mo

81 n the SLAM approach and ways to address such shortcomings by combining SLAM with inverse methods are

82 Here, we address these shortcomings by developing region-specific SDRs for Euro

83 tic engineering strategies to overcome these shortcomings by integrating CRISPR/Cas9 system into a te

84 this gap in knowledge and overcome previous shortcomings by thoroughly examining music effects acros

85 Here, we show that this shortcoming can be circumvented through an injectable, i

86 lear benefits, but because of methodological shortcomings comparative studies with uniform patient se

87 Failure to address this shortcoming could increase morbidity and mortality as a

88 Despite various shortcomings, disease severity is generally determined b

89 findings that may result from methodological shortcomings (e.g. small sample size, no valid stressor)

90 ever, these approaches are not without their shortcomings; enzymatic amplification and ligation of ol

91 We address this shortcoming first through an interdisciplinary ensemble

92 However, there are presently shortcomings for both the extensively studied bilayer ep

93 ommon modalities and specific advantages and shortcomings for each are reviewed.

94 technologies, describe their advantages and shortcomings for engendering useful genetic alterations,

95 These shortcomings have been recently addressed by restricting

96 ing centrality algorithms also have a second shortcoming, i.e., the list of the most central nodes ar

97 Here, we outline its shortcomings, illustrate how these can lead to misguided

98 A key shortcoming in meeting this challenge has been the lack

99 A major shortcoming in olefin metathesis, a chemical process tha

100 One prominent shortcoming in oncology is a high frequency of false-pos

101 e than 50 degrees C, which addresses a major shortcoming in plasmon actuated cargo delivery systems.

102 One major shortcoming in previous studies of ion-irradiated films

103 applied to mouse liver tissue suffers from a shortcoming in terms of sensitivity for lower abundance

104 This shortcoming in the current U.S. NOx control policy is ex

105 The principal shortcoming in the lack of accurate and precise alignmen

106 rade toxic effects; we aimed to address this shortcoming in this study.

107 in this system, also highlights a potential shortcoming in using density or abundance as a metric of

108 Despite its shortcomings in accuracy, hierarchical clustering is the

109 s employed for electrochemical analysis have shortcomings in actual homecare applications.

110 ative BTA, and Cxbladder; and methodological shortcomings in almost all studies.

111 importance of imaging in ophthalmology, the shortcomings in current image management systems need to

112 hand, but also allowed the identification of shortcomings in current theoretical approaches.

113 Their effectiveness and shortcomings in determining carbon contamination are pre

114 ted self-insight is not necessarily implied: Shortcomings in either exercise could be implicated, whe

115 dress these challenges, but known BVMOs have shortcomings in either stability or substrate selectivit

116 Major shortcomings in experimental research center on the diff

117 lattice during VLP assembly or are caused by shortcomings in interactions of Gag with essential and s

118 We addressed three major shortcomings in miRNA FISH, identifying optimal conditio

119 Shortcomings in our understanding and promising areas fo

120 PR/Cas9 is still questionable due to current shortcomings in phage-based delivery systems such as ine

121 cuss general and pervasive model-independent shortcomings in preclinical oncology work, and we propos

122 ost affected by the epidemic, and to redress shortcomings in realizing population-level HIV preventio

123 d technique for mixture analysis, but it has shortcomings in resolving carbohydrate mixtures due to t

124 There have been serious shortcomings in statistical methods for the evaluation o

125 Shortcomings in study design and data reporting, as well

126 Shortcomings in study design, including channeling, conf

127 nctional endpoints, but there were important shortcomings in the agent and/or the trial design in eac

128 we evaluate that study and find significant shortcomings in the analysis.

129 rmore, we point to empirical and theoretical shortcomings in the authors' case, such as a failure to

130 Despite shortcomings in the evidence base, several studies show

131 We have found substantial shortcomings in the handling of confounding and effect m

132 In addition, there are shortcomings in the prediction of GVHD before clinical s

133 e power of the QM/MM approach and identified shortcomings in the use of nonhydrolyzable substrate ana

134 However, shortcomings in this research limit the findings.

135 Although shortcomings in viral vector properties will render exte

136 hough each approach suffers from significant shortcomings, in combination, the methods described prov

137 Moreover, the existing software has some shortcomings including the requirement for significant m

138 ional, and most had important methodological shortcomings, including failure to adjust for potential

139 g, and as such these algorithms have several shortcomings, including susceptibility to false positive

140 cacy, as well as for the ability to overcome shortcomings inherent with conventional active vaccinati

141 Here, this shortcoming is addressed via a quintuple-detector size-e

142 This shortcoming is important because health is affected by f

143 However, because every model has shortcomings, it is important to understand how predicti

144 l reporter systems have been developed, many shortcomings limit their use in the assessment of HCV in

145 This shortcoming makes it very challenging to diagnose and tr

146 This shortcoming markedly limits the interpretability of the

147 A key to remedying these shortcomings may lie in a better understanding of long-l

148 We conclude that despite a number of shortcomings, Mexico is better set to develop biological

149 f robust design and important methodological shortcomings, negatively influencing generalizability.

150 on morphology and size that may overcome the shortcoming of 2DTEE, leading to a better prediction of

151 cting bad luck for researchers rather than a shortcoming of American voters.

152 This shortcoming of bacterial expression systems is particula

153 One potential shortcoming of current approaches to Alzheimer disease d

154 oves the widely accepted explanation for the shortcoming of current III-V QD syntheses and points to

155 ork, we analyzed causes for a recently noted shortcoming of filtration models, which is to predict co

156 A common shortcoming of ICDs is imperfect rhythm discrimination,

157 One shortcoming of Kurzban et al.'s model is that it is not

158 A shortcoming of many gene expression control studies is t

159 The shortcoming of most refractive index (RI)-based label-fr

160 Our study illustrates an underappreciated shortcoming of siRNA gene knockdown technology.

161 A shortcoming of the PLUM was the inability to separate la

162 Another shortcoming of the previous studies stems from their use

163 A shortcoming of these drugs is their inability to target

164 A major shortcoming of these theories is that they lack a solid

165 The shortcoming of this approach is that the attenuating mut

166 A shortcoming of this model is that clonally expanded prec

167 One shortcoming of traditional KAT assays is their inability

168 A major shortcoming of WES is uneven coverage of sequence reads

169 ts antagonists, and some of the triumphs and shortcomings of alphaIIbbeta3 antagonism.

170 rpose of this commentary is to (1) highlight shortcomings of and potential pitfalls in BiFC assays, (

171 ented in this study, and on the demonstrated shortcomings of array-based approaches, we argue for a c

172 ery disease (CAD) but subject to the various shortcomings of available radiotracers.

173 The shortcomings of BCC interventions are partly due to barr

174 In order to overcome the shortcomings of biological experimental methods, many co

175 h a critical analysis of both the merits and shortcomings of carbon nanotube transparent conductive f

176 Their stories reveal shortcomings of common perspectives on medical decision

177 The algorithm improves upon shortcomings of computer vision by effectively recognizi

178 present concepts in tumor heterogeneity, the shortcomings of conventional targeted systems, lessons l

179 t including a lack of new molecular targets, shortcomings of current animal models, and the lack of b

180 BS diagnosis (particularly the strengths and shortcomings of current criteria), definitions used in c

181 problem is a consequence of the fundamental shortcomings of current estimation techniques under inte

182 easured at the point of care, overcoming the shortcomings of current instrumentation.

183 This paper discusses the shortcomings of current metabolomics data analysis techn

184 ally sighted corneal light reflex avoids the shortcomings of current ocular axes for clinical applica

185 e potential value of genetic testing and the shortcomings of current pathways to access testing.

186 novel cancer genes and addresses many of the shortcomings of current tools.

187 ergy and Clinical Immunology, highlights the shortcomings of current treatment guidelines for patient

188 immediate and long-term), and challenges and shortcomings of currently available treatment options; a

189 lar scaffolds were developed to overcome the shortcomings of drug-eluting stents in percutaneous coro

190 We discuss the advantages and shortcomings of each approach, and present and review th

191 evels can create a system that mitigates the shortcomings of each of the individual mechanisms.

192 objective is to highlight the strengths and shortcomings of each technique and summarize lessons we

193 ion in drought responses, the advantages and shortcomings of each, and what each of these approaches

194 To overcome the shortcomings of electroanalytical methods in analyzing t

195 STAR addresses some of the shortcomings of existing Golden Gate or solid-phase asse

196 Shortcomings of existing instrumentation are also noted.

197 neering techniques may alleviate some common shortcomings of existing models of viral infection, with

198 proposed SDM-based clustering overcomes the shortcomings of Fuzzy C-means which focuses purely on wi

199 tic approach of GEPNETs and can overcome the shortcomings of histopathologic grading especially in in

200 may have implications for understanding the shortcomings of host response in newborns where TACI exp

201 Despite recognized shortcomings of in vivo animal models, the underlying pa

202 approach to religion not only avoids various shortcomings of institutional approaches, but also offer

203 However, several shortcomings of OECD 308 have been identified that hampe

204 are promising candidates to address existing shortcomings of other infrared-emissive nanomaterials.

205 a general strategy to supplement some of the shortcomings of otherwise highly useful circulating biom

206 t refute this conclusion, nor do the claimed shortcomings of our modeling have validity.

207 The strengths and shortcomings of passive sampling are assessed for water,

208 To address the shortcomings of past guidelines, the Institute of Medici

209 polation have been widely used to offset the shortcomings of PM2.5 data observed at sparse monitoring

210 Our study was designed to overcome the shortcomings of previous double-blinded trials of househ

211 l assessment of the current applications and shortcomings of previously proposed biomarkers.

212 inically established RNR inhibitors have the shortcomings of short half-life, drug resistance, and ir

213 omising new strategy that might overcome the shortcomings of single gene testing in colorectal cancer

214 inferences are neither due to methodological shortcomings of specific measurements nor due to artifac

215 long-term toxicities and chemoresistance are shortcomings of standard chemotherapy.

216 d clinical heterogeneity, and methodological shortcomings of studies.

217 l differentiation and function is limited by shortcomings of suitable and scalable experimental syste

218 ry systems have been studied to overcome the shortcomings of systemic delivery.

219 Study limitations include potential shortcomings of the adherence measures and use of a conv

220 parisons with DFT calculations highlight the shortcomings of the B3LYP functional in properly depicti

221 The shortcomings of the black box-idea of mtROS are discusse

222 demonstrated it to be an improvement on the shortcomings of the current industry "gold standards" DO

223 ecorporate iron are reviewed, along with the shortcomings of the currently available therapeutics.

224 miliarize themselves with the advantages and shortcomings of the NCDB, as well as its evolution over

225 the Gini correlation can compensate for the shortcomings of the Pearson correlation, the Spearman co

226 08 to 2013 and qualitatively explain certain shortcomings of the previous approach.

227 The basis for the new design have been the shortcomings of the previous ion mobility spectrometers,

228 It highlights the shortcomings of the RV144 vaccination trial [ALVAC-HIV (

229 tile techniques, compares the advantages and shortcomings of these approaches, outlines the use of co

230 We discuss differences, advantages, and shortcomings of these two approaches.

231 ntitative approach elegantly illustrates the shortcomings of this still-entrenched viewpoint.

232 ugh theory and simulations the strengths and shortcomings of three SNP-based inbreeding measures comm

233 asive genotyping while avoiding the inherent shortcomings of tissue genotyping and repeat biopsies.

234 vibrations in liquid H2O, and illustrate the shortcomings of traditional relaxation models.

235 Vote maps illustrate the potential shortcomings of using a limited number or type of tomogr

236 ally interesting, especially considering the shortcomings of vaccines in protecting against noninvasi

237 9)Zr-alphaGPC3-F(ab')2 addresses some of the shortcomings of whole-antibody immuno-PET probes.

238 The impact of this shortcoming on mortality for patients with end-stage ren

239 sual care was limited and had methodological shortcomings, precluding strong conclusions.

240 This shortcoming reflects the combinatorics and multiple-test

241 t on modern organic chemistry, but important shortcomings remain: for example, the lack of efficient

242 laser-accelerated ion beams, addresses these shortcomings simultaneously.

243 ntly used for uncertainty analysis have some shortcomings: statistical uncertainty analysis via Monte

244 hniques for determining adenine have several shortcomings such as high cost, high time consumption, t

245 approach is of prognostic value, it harbours shortcomings such as ill-defined parameters for subtypes

246 Although mass cytometry has some shortcomings such as inability to analyze potential tran

247 o overcome their intrinsic biopharmaceutical shortcomings, such as poor enzymatic stability, rapid bo

248 rs, eventually embody several methodological shortcomings, such as the lack of time-dependency and in

249 This article examines the serious shortcomings that characterize the current taxonomy of p

250 We identified methodologic shortcomings that contributed to these errors in the med

251 but one of the trials did have methodologic shortcomings that may have allowed the introduction of b

252 However, redistricting has the shortcomings that Organ Procurement Organizations (OPOs)

253 However, their model suffers from shortcomings that reduce its applicability to empirical

254 utational methods and draws attention to the shortcomings that their application has brought to light

255 tions and these suffered from methodological shortcomings, the evidence appears to support the cost-e

256 Despite these shortcomings, the human imiquimod model might be useful

257 ds, with an emphasis on their advantages and shortcomings; then it summarizes major findings on the e

258 To overcome this shortcoming, there is an urgent need to identify appropr

259 Addressing this shortcoming, this study presents an actor-oriented analy

260 This paper addresses this shortcoming, through a hybrid approach that estimates th

261 llular transformation and represents a major shortcoming to current therapeutic strategies and the ab

262 cted to closely related species is a central shortcoming to their translational development.

263 There are substantial shortcomings to the various preclinical animal models, a

264 parent success, however, masks a fundamental shortcoming: topological insulators represent only a few

265 To overcome this shortcoming two sensors were assembled with a canted ang

266 to better understand the reasons behind this shortcoming we categorise peptide self-assembled materia

267 To address this shortcoming, we constructed a novel and safer gene trans

268 To address this shortcoming, we created a generalizable protein knock-ou

269 In order to overcome this shortcoming, we demonstrate the use of a living contrast

270 To remedy this shortcoming, we designed the first consistent elastic mo

271 To address this shortcoming, we developed a long Stokes shift RFP-based

272 To address this shortcoming, we developed Clonify, which is able to perf

273 To address this shortcoming, we have developed a robust, high-throughput

274 To address this shortcoming, we measured trace metal concentrations in t

275 To remedy this shortcoming, we present a new genetic annotation approac

276 To address this shortcoming, we present Sushi.R, an R/Bioconductor packa

277 To address this shortcoming, we produced a novel transgenic quail that u

278 To address these shortcomings, we assessed the stoichiometric efficiency

279 To alleviate such shortcomings, we demonstrate a simple route toward the r

280 To address these clinical shortcomings, we developed a synthetic polycation, Unive

281 To address these shortcomings, we established an ex vivo 3D Ewing sarcoma

282 Considering these shortcomings, we explored the possibility of constructin

283 To overcome these shortcomings, we have combined loop-mediated isothermal

284 To address these shortcomings, we have developed an N-glycan labeling rea

285 To overcome these shortcomings, we here introduce the MetaProteomeAnalyzer

286 Because existing studies have shortcomings, we present a large, unselected cohort of p

287 To address these shortcomings, we sought to design a family of HP-beta-CD

288 port responsive surfaces that overcome these shortcomings: we achieve fault-tolerant behavior based o

289 Methodologic shortcomings were identified by the adoption of the Crit

290 The main shortcomings were identified in the steps of pre-process

291 The most common shortcomings were observed in items related to anthropom

292 Potential shortcomings were recognized, and lessons learned will p

293 d treatment assessment assays, however, face shortcomings when applied to these large, complex, and h

294 come increasingly popular to emphasize their shortcomings when translating observations to humans.

295 Similarly, such shortcomings will limit the programmatic usefulness of M

296 One shortcoming with its use is that Mcl-1, a member of the

297 The non-disclosure patterns suggest shortcomings with authors and the rigor of journal pract

298 ment patterns because they overcome inherent shortcomings with the prevailing paradigm - discrete ran

299 titude observations are essential because of shortcomings within climate models in their depiction of

300 To overcome these shortcomings without degrading temporal resolution, ultr