ライフサイエンスコーパス: shorten

1 es (cell shortening) and in vivo (fractional shortening).

2 ir gamma-static fusimotor drive when muscles shorten.

3 h reflex whose amplitude decreases as muscle shortens.

4 shold responses, latencies were consistently shortened.

5 hin attachment pad associated with flagellum shortening.

6 ng G-quadruplexes which can lead to telomere shortening.

7 ve to reference tissues that did not show T1 shortening.

8 ons produced distinct effects on IK1 and APD shortening.

9 ons in both longitudinal and circumferential shortening.

10 ation of Slc26a6 results in action potential shortening.

11 inks, leads to stereocilia shape changes and shortening.

12 w rate of ATP utilization during extended V0 shortening.

13 t allow operations like chain elongation and shortening.

14 ate of ATP utilization found during unloaded shortening.

15 d force during the force redevelopment after shortening.

16 siological recordings is reflected in muscle shortening.

17 ation imposed by zinc addition leads to cell shortening.

18 tection against mutant LRRK2-induced neurite shortening.

19 , while the orogeny accommodates most of the shortening.

20 R4-NOT complex function in mRNA poly(A) tail shortening.

21 ce during the force development following V0 shortening.

22 , whereas topo-II promotes chromosome-length shortening.

23 he well-characterized phenotype of dendritic shortening.

24 2 vs. +4.2), and left ventricular fractional shortening (16% vs. 17%) at diagnosis were similar betwe

25 weeks (ejection fraction, -45.6%; fractional shortening, -22.6%).

26 ction fraction %, 54.76 +/- 0.67; fractional shortening %, 27.53 +/- 0.50) compared with sham control

27 ction fraction %, 71.60 +/- 4.02; fractional shortening %, 39.63 +/- 3.23).

28 ction fraction %, 73.06 +/- 6.31; fractional shortening %, 42.33 +/- 5.70) compared with sham S2814A

29 ction fraction %, 73.57 +/- 0.20; fractional shortening %, 46.75 +/- 0.38).

30 Telomere shortening, a marker of cellular ageing, is linked with

31 t, increased fast Ca(2+) buffering strength, shortened action potentials and reduced L-type Ca(2+) cu

32 ene expression and hERG currents (IhERG) and shortened action-potential duration (APD).

33 Manganese has long been employed as a T1-shortening agent in magnetic resonance imaging (MRI) app

34 ons in both circumferential and longitudinal shortening (all p < 0.01).

35 ined; all but three are depleted of the life-shortening alleles in older Biobank participants.

36 The use of this cell allowed to shorten analysis time and to decrease the sample volume.

37 rovides the following benefits: ease of use, shortened analysis time, and decreased analysis cost.

38 he ability of their cylindrical cell body to shorten and elongate upon cell depolarization and hyperp

39 ombination indicated that axonemes gradually shorten and outer segments progressively degenerate.

40 Improved drug regimens to shorten and simplify treatment are urgently required, ho

41 cilia initially developed normally but later shortened and disappeared; surprisingly, stereocilia wid

42 n, and therefore interepisode interval, also shortened and slowed activity, suggesting that pump acti

43 changes, including a general trend of 3'UTR shortening and activation of intronic APA isoforms.

44 arts exhibited a 36% reduction in fractional shortening and an increased diastolic ventricular chambe

45 "hand-over-hand" longitudinal pulling causes shortening and bending of platelet-attached fibers, resu

46 tants after accidental release through chain shortening and biotransformation, emphasizing the import

47 linking the SV with the PM, varies by random shortening and lengthening of the macromolecules at rest

48 developed MC model accurately reproduced AP shortening and reduced effective refractory period assoc

49 Insofar as telomere shortening and replicative senescence prevent genomic in

50 ng of the Indian continental lithosphere and shortening and thickening of the Northern Tibetan lithos

51 The value of n decreases progressively with shortening and, during V0 shortening starting at the end

52 Unexpected shortening (and, thus, strengthening) of the O-H...O hor

53 ility was determined in cardiomyocytes (cell shortening) and in vivo (fractional shortening).

54 recombination at telomeres, delayed telomere shortening, and postponed senescence onset.

55 ells transit back to myelinating cells, they shorten approximately 7-fold to generate the typically s

56 Telomere length and telomere shortening are associated with age-related health outcom

57 increases more slowly, the marginal band may shorten as microtubules slide relative to each other.

58 To prevent progressive telomere shortening as a result of conventional DNA replication,

59 ction against mutant LRRK2-elicited dendrite shortening, as did inhibiting MCU-mediated calcium impor

60 al, Wenckebach cycle length, and AH interval shortening, associated with a negative response to atrop

61 F-fibre latency does not shorten at temperatures above 30 degrees C.

62 t placed in a rigor state then stretched and shortened at different displacements (0.1-0.3 mum per sa

63 contraction (by motility assay or sarcomeric shortening) at different actin concentrations (which is

64 ) to identify the level of AP duration (APD) shortening attributed to KATP channel activation.

65 Additionally, a shortened beta1-beta2 linker allows for the formation of

66 loss of function in the zebrafish results in shortened body axis, microphthalmia with disorganized le

67 ggested that against this overall pattern of shortening, bouts of telomere length increase occur in s

68 deletion of rad51 and blm separately caused shortened but stably maintained telomeres, whereas delet

69 ial phase, TPMs do not prevent bulk telomere shortening but extend cellular life span by healing the

70 otonin reuptake inhibitor use, gestation was shortened by 1.8 days, 152 of 1000 additional newborns r

71 ATP hydrolysis cycle 3.7-fold, whereas it is shortened by 27 and 63% in the presence of Tpm1.8 and Tp

72 1000 neonates and duration of gestation was shortened by 3.6 days; with maternal serotonin reuptake

73 +) ions observed as the glycan antennae were shortened by stepwise exoglycosidase treatments; this tr

74 th this, polyphosphate quantification can be shortened by use of Raman microscopy from days to hours

75 stent peritonitis cells showed reduced cell shortening, Ca transient amplitude and sarcoplasmic reti

76 icroM of KN93 prevented the decrease in cell shortening, Ca transient amplitude, and sarcoplasmic ret

77 "Air Suction" could extremely shorten capture.

78 f the hallmarks of aging, including telomere shortening, cellular senescence, activation of PI3 kinas

79 ability phenotypes, such that when telomeres shortened, chromosome instability increased and when tel

80 ng the switch into the trans isomer leads to shortened circadian periods.

81 placebo group (*p = 0.018), indicative of a shortened clonal evolution treated sulindac.

82 Moreover, midazolam shortened cortical up states at low, but not at high con

83 season (during which time food is ample) and shortening critical development time (the period from th

84 e-stain electron microscopy on a recombinant shortened CSP (rsCSP) construct saturated with Fabs.

85 mouse model studies, treatment with mAb 2E8 shortened DENV-induced prolonged bleeding time and reduc

86 Ag expression at skin inoculation sites and shortened DENV-induced prolonged bleeding time.

87 imensions, ejection fraction, and fractional shortening) deteriorated in TNC-deficient mice compared

88 Warmer temperatures consistently shortened development time without costs to embryo mass

89 hancing surface thermodynamic contributions, shortening diffusion lengths, and increasing the number

90 sed protein and carbohydrate extractability, shortened dough development time, reduced gel strength a

91 for >/=80% of the final R-R and AH interval shortening during ablation.

92 nals are critical for the regulation of cell shortening during initial MHB formation.

93 s, reduced ejection fraction, and fractional shortening (ejection fraction %, 54.76 +/- 0.67; fractio

94 d preserved ejection fraction and fractional shortening (ejection fraction %, 73.06 +/- 6.31; fractio

95 he life span of affected organisms is barely shortened, enabling the transfer of radionuclides throug

96 pisode duration, whereas monensin slowed and shortened episodes.

97 tely after unreinforced lever presses during shortened extinction sessions decreased lever pressing d

98 he IL increased active lever pressing during shortened extinction sessions, but did not alter the ret

99 Left ventricular shortening fraction, ejection fraction, mass, and fracti

100 y potentiated, unless the pre-post delay was shortened from 10 to 5 ms, which selectively potentiated

101 the photoluminescence) and carrier lifetime shortening (from approximately 18.3 +/- 0.8 to approxima

102 To develop a shortened glaucoma symptom measure based on the Collabor

103 1 long-range resection pathway significantly shortened hetDNA, suggesting that these pathways normall

104 y US hospitals are implementing protocols to shorten hospitalization after major surgery.

105 imum velocity at which a skeletal muscle can shorten (i.e. the velocity of sliding between the myosin

106 otors per half-myosin filament (n) during V0 shortening imposed either at the end of LR or at the pla

107 of T cells and that telomeres progressively shorten in a heterogeneous population of T cells, even i

108 protective caps at the ends of chromosomes, shorten in response to oxidative stress, and telomere sh

109 ysiological tremor increased as calf muscles shortened in contrast to the stretch reflex whose amplit

110 n and the following R peak was significantly shortened in MCS when the auditory rule was violated.

111 asal septum to be abnormally mineralized and shortened in Mgp(-/-) mice.

112 Median survival was significantly shortened in overt PMF (7.2 vs 17.6 years), with triple

113 3-induced thrombosis model was significantly shortened in the TRAF3 knockout mice.

114 sed cardiac ejection fraction and fractional shortening in aged (24-month-old) mice and Ang II-infuse

115 eatment with BRD4 inhibitors caused telomere shortening in both mouse and human cells, suggesting BRD

116 and with a higher prevalence of postsystolic shortening in FGR as compared with controls.

117 Here, we demonstrate that telomere shortening in NOTCH1-haploinsufficient mice is sufficien

118 Significantly, 3' UTR shortening in S. pombe coordinates with up-regulation of

119 (2+) load, together with decreased sarcomere shortening in Slc26a6(-/)(-) cardiomyocytes.

120 dministrations showed visually detectable T1 shortening in the dentate nucleus (n = 13), globus palli

121 reveal progressive, eastward steepening and shortening in the horizontal advance of the subducting I

122 Telomere shortening induces chromosomal instability that, in the

123 eaction mechanism, abundant active sites and shortened ion diffusion distance.

124 Sheath shortening is associated with a low frequency of [Ca(2+)

125 n response to oxidative stress, and telomere shortening is correlated with reduced survival and life

126 rtening (range 30-80 nm per hs) and, when V0 shortening is imposed at the end of LR, n can be as low

127 g due to musculus syringealis ventralis (VS) shortening is intrinsically constraint at maximally 12%

128 Telomere shortening is proposed to be a primary molecular cause o

129 When V0 shortening is superimposed on the maximum isometric forc

130 With shortened isolation times and improved mitochondrial pur

131 increasing its polyubiquitination level and shortening its half-life from 24 h to approximately 3.5

132 beta-TrCP1 promotes FBXW2 ubiquitylation and shortens its half-life, FBXW2 does the same to SKP2.

133 phasize that Pinatubo-like eruptions tend to shorten La Ninas, lengthen El Ninos and induce anomalous

134 Finally, TC-PTP knockout mice showed a shortened latency of tumorigenesis and significantly inc

135 care by reducing unnecessary antibiotic use, shortening length of hospital stay, improving influenza

136 ians were blinded to results unless cervical shortening less than 15 mm was identified.

137 stolic dysfunction was defined as fractional shortening less than 25%.

138 blockade LH surge, while RU486 into the ARC shortened LH pulse interval in the progesterone treated

139 High milk consumption might shorten life span through increased oxidative stress.

140 eural effusions have significant dyspnea and shortened life expectancy.

141 ramatic nephrocyte functional impairment and shortened life span, as well as collapse of nephrocyte l

142 ned silencing or sustained loss of silencing shortens life span.

143 with Asxl2(-/-) and Asxl2(+/-) BM cells have shortened lifespan due to the development of MDS-like di

144 ant flies and found that loss of Atg9 led to shortened lifespan, locomotor defects, and increased sus

145 on of ageing-like physiological changes or a shortened lifespan.

146 ult tissue morphology and functionality, and shortened lifespan.

147 g exc-7, double mutants displayed a severely shortened lifespan.

148 Tsc2cKO(Prrx1-cre) mice had shortened lifespans and extensive hamartomas containing

149 d growth may also mean more rapid ageing and shortened lifetime.

150 ic condition characterized by short stature, shortened limbs, and facial dysmorphism.

151 e we constructed a mutant murine P-gp with a shortened linker to facilitate structural determination.

152 odystrophy in dogs is defined by dysplastic, shortened long bones and premature degeneration and calc

153 er slope <5 Hz (i.e., greater alpha activity shortened LRD).

154 c and cell survival pathways that prolong or shorten macrophage development and viability, the tissue

155 shing of PFCs can contaminate the plasma and shorten material lifetime.

156 RIPC significantly shortened mechanical ventilation (MV) duration [weighted

157 Acute native shortened modified look-locker inversion recovery T1 map

158 - to C-state does not occur, although during shortening muscle stiffness is reduced compared to the i

159 ine 123 and calcein-AM transport, the linker-shortened mutant P-gp possesses basal ATPase activity an

160 RIPC may also shorten MV duration and ICU stay.

161 hed motors per half-thick filament during V0 shortening (n) is estimated by imposing, on tetanized si

162 de repeat disorders are severe, usually life-shortening, neurological disorders caused by nucleotide

163 One of the factors most contributory to the shortening of a surgeon's career is work-related pain an

164 The possible factors associated with the shortening of lead time between ocean warm water volume

165 the compression of morbidity, measured as a shortening of life expectancy with disability, an extens

166 The primary outcome was shortening of P100 latency delay on full-field, pattern-

167 ing pathway in which the formation and chain-shortening of polysulfide occur at early stage accompani

168 through contractile mechanisms that involve shortening of sarcomeres along myofibrils.

169 The shortening of target sequences through use of two target

170 ation to soluble TcO4(-)) resulted from both shortening of TcO2 chains during redox cycling and assoc

171 myocytes and embryonic zebrafish resulted in shortening of the atrial action potential duration, a ha

172 ng, the PAS domain contracts, resulting in a shortening of the C-terminal beta-strand.

173 Substantial shortening of the Ce horizontal lineN bond was observed

174 ce of the UCNP donor revealed a considerable shortening of the donor lifetime as a clear hint for For

175 cluding growth retardation, disproportionate shortening of the limbs, round head, mid-face hypoplasia

176 ence of ribonucleotides induces a systematic shortening of the molecules, together with a decrease of

177 signals that are spectrally identifiable and shortening of the MRI relaxation times T 1 and [Formula:

178 , especially the tip of the nose, indicating shortening of the nose and upturning of the nose tip.

179 lation of Shh signaling is associated with a shortening of the primary cilium length and with a reduc

180 patients, 7%), lack of elongation effect or shortening of the prosthesis (7 patients, 4.5%), prosthe

181 ng of the Si-O-Si dihedral angle rather than shortening of the Si-O bond, and consequently there is n

182 Facial retrusion, the proximodistal shortening of the snout and widening of the hard palate

183 ack of C-strand maintenance leads to gradual shortening of the telomeric dsDNA, similar to that obser

184 Kinesin-4-mediated shortening of these overlaps at the onset of cytokinesis

185 ven more so, of principal cells can reliably shorten or abolish seizures in vitro Our work suggests t

186 Various approaches using shortened or interrupted acquisitions were compared with

187 ations of caudal sites in 8Av (close to FEF) shortened or prolonged saccadic reaction times, dependin

188 at the tips of dendrite branches, leading to shortening or removal of dendrites.

189 ther such increases reflect substantial life shortening or short-term displacement of deaths (harvest

190 the dogs lacking cone ERG are truncated with shortened outer and inner segments.

191 e will be useful to identify children with a shortened PAAT.

192 ds to increased stemness, tumorigenicity and shortened patient survival.

193 erated tissue factor-bearing microparticles, shortened plasma-clotting times, and increased thrombus

194 , global warming can disrupt connectivity by shortening potential dispersal pathways through changes

195 Here, we show that substrate shortening progressively destabilizes the consecutive en

196 decreases progressively with the increase of shortening (range 30-80 nm per hs) and, when V0 shorteni

197 ighest reticulocyte counts and concomitantly shortened RBC lifespans.

198 m [1-7] and can increase task efficiency via shortening reaction times and saving on neural tissue [8

199 lding solvent-free synthetic procedures, and shortens reaction times, among others.

200 h ROL or Bt2cAMP at the peak of inflammation shortened resolution intervals, improved resolution indi

201 isual stimulation (F1 values), significantly shortened response latency, and dramatically increased r

202 ered TB mortality by 3% (95% UR: 1%-6%), and shortening RR TB treatment from 20 to 6 mo reduced RR TB

203 ce had smaller but still substantial impact: shortening RS TB treatment duration from 6 to 2 mo lower

204 nd purification with 1-butanol significantly shortened sample preparation (30min) and provided clear

205 ot phenotypes including upward leaf curling, shortened siliques and narrow lateral branch angles.

206 ll, increased ejection fraction and fraction shortening, so as to inhibit HF at 2 weeks after TAC.

207 Here, we show that loss of Dlx5 leads to a shortened soft palate and an absence of the levator veli

208 progressively with shortening and, during V0 shortening starting at the end of LR, is 1-4.

209 nge of 0.15-0.275 nm(-1) was observed during shortening suggesting that an azimuthal Tpm movement fro

210 atio, 0.86; 95% CI, 0.83-0.89; P < .001) and shortened survival (hazard ratio, 0.92; 95% CI, 0.88-0.9

211 y abolished rebound delays and, importantly, shortened synaptically evoked inhibitory pauses, thereby

212 ed with group 1-5 media showed significantly shortened T2 relaxation times compared with unlabeled co

213 This study provides evidence that shortened telomere length is associated with familial ri

214 ue to NOTCH1 haploinsufficiency in mice with shortened telomeres were concordant with proosteoblast a

215 rom female rats displayed greater fractional shortening than males, and female ARVMs and myofibrils t

216 rved a rarely observed process of acyl chain shortening that likely induces membrane thinning, along

217 051 can reverse SGK1's effects on NaV1.5 and shorten the action potential duration in induced pluripo

218 nd is retracted to extend the Ser65 loop and shorten the C-terminal tail.

219 ows that two kinesin-4 motor proteins act to shorten the domain of overlapping microtubules at the ph

220 with medications during pregnancy, which can shorten the duration of gestation slightly.

221 ered that both inbred and outbred rats could shorten the duration of SWDs to obtain a reward.

222 6), can interfere with DNA gate dynamics and shorten the dwell time in the closed state.

223 ically from KTs, we show that KT-derived MTs shorten the half-life of noncaptured KTs from 48-49 s to

224 ely and permanently reduce the fertility and shorten the lifespan of adult females.

225 xins, that are shed into the environment and shorten the lifespan of both sexes.

226 ificantly reduce the reagent consumption and shorten the reaction and analysis time by utilizing nano

227 al toxicology-assessment package in order to shorten the route to human studies and reduce its cost.

228 tuberculosis infection (preventive therapy), shorten the time between disease onset and treatment ini

229 the drugs used for PrEP) would substantially shorten the time for cost savings to be realised.

230 e peak median VL by approximately 3 logs and shorten the time to undetectable median VL by approximat

231 Gain-of-function mutations shortened the action potential duration in single cells,

232 high dose expedited the renal excretion and shortened the blood retention.

233 the active site serine residue (FXII-S544A), shortened the clotting time of FXII-deficient plasma and

234 eased cumulative biogas production, but also shortened the duration for a stable biogas production ra

235 ld more beating iCMs than retroviral-GMT and shortened the duration to induce beating cells from 30 t

236 Moreover, PTPRO phosphatase activity shortened the half-life of ERBB2 by increasing endocytot

237 o in MMTV-Erbb2 transgenic mice dramatically shortened the mammary tumor latency and accelerated tumo

238 nor supplementation increased motivation and shortened the minimum stimulus length required for a cor

239 Acute lung inflammation slightly shortened the residence time of the anti-IL-17A and anti

240 ne, doxorubicin, and cyclophosphamide, which shortened the treatment duration from 49 to 29 days.

241 r than commercial Pd/C (0.72 A per mgPd), by shortening the distance between Pd and Ni active sites,

242 ing embryo-splitting approach, we found that shortening the half-life of Cas9 in fertilized zygotes r

243 ng granulomas will be vital to improving and shortening the long course of TB treatment.

244 increments less than 0.02 A correspondingly shortening the proton transfer pathway.

245 impeding exit from naive pluripotency and by shortening the S-G2/M phases.

246 Shortening the scan duration to 45 min provided similar

247 1b infection without cirrhosis are limited; shortening the treatment duration might reduce the burde

248 However, shortening the treatment duration to less than 8 weeks c

249 Shortening the work:recovery durations (16:32 s vs. 32:6

250 We demonstrate that ethylene shortens the circadian period, conditional on the effect

251 RATIONALE: Caffeine in the newborn period shortens the duration of assisted ventilation and reduce

252 on of Ornithodira (pterosaurs and birds) and shortens the ghost lineage inferred at the base of Aveme

253 I)) or hypoxia reduces the protein level and shortens the half-life of cytoplasmic Plk3 in a ubiquiti

254 N double knockout GBM mouse model additively shortens the latency of glioma onset and survival compar

255 ministic bistability-and promoter activation shortens the lifetime of this transient threshold.

256 e dominant minor allele of rs1079597 on DRD2 shortens the onset age range.

257 nstitutive HDAC4 localization in the nucleus shortens the period of MSDR.

258 The pipeline shortens the time line, but it most prominently reduces

259 The method described shortens the time required for the sample to be digested

260 l rearrangement of a single channel directly shortens the tip link.

261 n assessment of bleeding with CT angiography shortens the total diagnostic time, which results in pro

262 surface and numerosity, whereas lengthening (shortening) the duration yielded under- (over-) estimati

263 When the linker is shortened, the diffusion distance is reduced proportiona

264 During shortening, the myofibril stiffness was independent of d

265 Without shortening, the wider cell-plate membrane depositions ev

266 were concerned that musculoskeletal pain may shorten their career.

267 the sodium content of meat products without shortening their shelf-life.

268 king these outbreaks is an important tool in shortening them and developing strategies to prevent the

269 , the protective ends of linear chromosomes, shorten throughout an individual's lifetime.

270 at a bradykinin B2 receptor antagonist would shorten time-to-resolution from ACE inhibitor-associated

271 ctive study is required to determine whether shortening time to physical therapy evaluation and treat

272 ective in verifying proper tip placement and shortens time to catheter utilization.

273 eter insertion verifies proper placement and shortens time to catheter utilization.

274 unpaired electron to the methyl protons that shorten Tm at T > 70 K in currently used labels.

275 nerations of telomerase deficiency telomeres shorten to the point of uncapping, causing defects most

276 ) diode-pumped Nd:YAG laser cavity, which is shortened to 10 mm in length and which contains an RIG f

277 y be capable of delivering further treatment shortening, to days rather than weeks, if combined with

278 Critical to improving TB-therapy is shortening treatment duration and increasing therapeutic

279 ing transition from isometric contraction to shortening under low load.

280 de preclinical proof-of-concept of treatment shortening using antibiotic+ABZ combinations to deliver

281 e) and provides novel insights into unloaded shortening velocities (declining with increasing slack l

282 orce-generating capabilities, faster maximum shortening velocities, and/or a difference in myosin hea

283 ric force-generating capabilities or maximum shortening velocities-as has long been suggested-but rat

284 Accordingly, the unloaded shortening velocity (V0 ) is already set at the end of l

285 ric force/cross-sectional area) and unloaded shortening velocity; (iii) myosin/actin ratio and myosin

286 delayed rectifier (IKs) channel critical for shortening ventricular action potentials during high bet

287 opulation Health Metrics Research Consortium shortened verbal autopsy questionnaire was used for each

288 )) formed thrombi at a faster rate and had a shortened vessel occlusion time.

289 ng affinity also decrease IFN inhibition and shorten VP24 half-lives.

290 Pregnancy was significantly shortened (vs. FA) by approximately 0.4d when exposure o

291 the Wenckebach cycle length and AH interval shortening was 18.1+/-11% and 24.6+/-19%, respectively.

292 Surfactant chain shortening was coupled to an increased abundance of the

293 Furthermore, the myofibril stiffness during shortening was greater than that during stretching and t

294 Microbial enzymatic chain shortening was responsible for a shift in ethoxymer mole

295 r whereas LV contractility and LV fractional shortening were higher when compared to the HAART-unexpo

296 ncreases in physiological tremor with muscle shortening - while successfully replicating the concomit

297 In most tissues, telomeres shorten with each round of cell division, placing a fini

298 the latency period to the onset of Ca waves shortened with reduced variance.

299 s-depressed mean left ventricular fractional shortening z scores (-7.85+/-3.98 versus -9.06+/-3.89, P

300 ciated with left ventricular (LV) fractional shortening (z-score for difference = 1.07; p = 0.02) and