ライフサイエンスコーパス: shortening

1 es (cell shortening) and in vivo (fractional shortening).

2 inks, leads to stereocilia shape changes and shortening.

3 w rate of ATP utilization during extended V0 shortening.

4 t allow operations like chain elongation and shortening.

5 ate of ATP utilization found during unloaded shortening.

6 d force during the force redevelopment after shortening.

7 siological recordings is reflected in muscle shortening.

8 ation imposed by zinc addition leads to cell shortening.

9 tection against mutant LRRK2-induced neurite shortening.

10 , while the orogeny accommodates most of the shortening.

11 of CDW and blended with a commercial bakery shortening.

12 nt of forced disruption of Tp53 and telomere shortening.

13 ude of ktr following step shortening or ramp shortening.

14 R4-NOT complex function in mRNA poly(A) tail shortening.

15 reduced TEL patch dosage in causing telomere shortening.

16 nancy leading to significant life-expectancy shortening.

17 ce during the force development following V0 shortening.

18 , whereas topo-II promotes chromosome-length shortening.

19 he well-characterized phenotype of dendritic shortening.

20 hin attachment pad associated with flagellum shortening.

21 ng G-quadruplexes which can lead to telomere shortening.

22 ve to reference tissues that did not show T1 shortening.

23 ons produced distinct effects on IK1 and APD shortening.

24 ons in both longitudinal and circumferential shortening.

25 ation of Slc26a6 results in action potential shortening.

26 versus 23%; P=<0.001) and midwall fractional shortening (15.9% versus 16.7%; P=0.001) were lower in P

27 2 vs. +4.2), and left ventricular fractional shortening (16% vs. 17%) at diagnosis were similar betwe

28 weeks (ejection fraction, -45.6%; fractional shortening, -22.6%).

29 ction fraction %, 54.76 +/- 0.67; fractional shortening %, 27.53 +/- 0.50) compared with sham control

30 ction fraction %, 71.60 +/- 4.02; fractional shortening %, 39.63 +/- 3.23).

31 ction fraction %, 73.06 +/- 6.31; fractional shortening %, 42.33 +/- 5.70) compared with sham S2814A

32 ction fraction %, 73.57 +/- 0.20; fractional shortening %, 46.75 +/- 0.38).

33 Telomere shortening, a marker of cellular ageing, is linked with

34 Manganese has long been employed as a T1-shortening agent in magnetic resonance imaging (MRI) app

35 ons in both circumferential and longitudinal shortening (all p < 0.01).

36 ined; all but three are depleted of the life-shortening alleles in older Biobank participants.

37 ttern strengthens the prevention of telomere shortening among Ala carriers.

38 ks psychosocial stress to premature telomere shortening and accelerated human aging; however, this as

39 changes, including a general trend of 3'UTR shortening and activation of intronic APA isoforms.

40 Telomere shortening and alterations of mitochondrial biogenesis a

41 arts exhibited a 36% reduction in fractional shortening and an increased diastolic ventricular chambe

42 "hand-over-hand" longitudinal pulling causes shortening and bending of platelet-attached fibers, resu

43 tants after accidental release through chain shortening and biotransformation, emphasizing the import

44 Cell shortening and calcium transients were measured on isola

45 ormalities translate into reduced fractional shortening and cardiac contractility at the in vivo leve

46 relative to body weight, as well as reduced shortening and ejection fractions.

47 1 (EB1) remains at the tip during flagellar shortening and in the absence of intraflagellar transpor

48 3s can regulate mutant LRRK2-induced neurite shortening and kinase activity.

49 linking the SV with the PM, varies by random shortening and lengthening of the macromolecules at rest

50 adenosine-induced action potential duration shortening and prevented AF induction.

51 ients of glutathione oxidation go along with shortening and re-elongation of the organelle.

52 developed MC model accurately reproduced AP shortening and reduced effective refractory period assoc

53 petent RyR2 displayed depressed AM sarcomere shortening and reduced in vivo atrial contractile functi

54 Insofar as telomere shortening and replicative senescence prevent genomic in

55 attenuated ectosome release during flagellar shortening and shortening was slowed.

56 losis and MDR-tuberculosis, with the goal of shortening and simplifying treatment.

57 ng of the Indian continental lithosphere and shortening and thickening of the Northern Tibetan lithos

58 of muscle to produce force and power during shortening and to alter the rate of force redevelopment

59 The value of n decreases progressively with shortening and, during V0 shortening starting at the end

60 Unexpected shortening (and, thus, strengthening) of the O-H...O hor

61 ility was determined in cardiomyocytes (cell shortening) and in vivo (fractional shortening).

62 recombination at telomeres, delayed telomere shortening, and postponed senescence onset.

63 ldhood adversity is associated with telomere shortening, and several investigations have shown short

64 Finding new treatment-shortening antibiotics to improve cure rates and curb th

65 Telomere length and telomere shortening are associated with age-related health outcom

66 To prevent progressive telomere shortening as a result of conventional DNA replication,

67 ction against mutant LRRK2-elicited dendrite shortening, as did inhibiting MCU-mediated calcium impor

68 al, Wenckebach cycle length, and AH interval shortening, associated with a negative response to atrop

69 contraction (by motility assay or sarcomeric shortening) at different actin concentrations (which is

70 ) to identify the level of AP duration (APD) shortening attributed to KATP channel activation.

71 After crystallizing the oleogel/shortening blends by using a pilot scale crystallization

72 ggested that against this overall pattern of shortening, bouts of telomere length increase occur in s

73 ial phase, TPMs do not prevent bulk telomere shortening but extend cellular life span by healing the

74 ies, they have been shown to induce telomere shortening, but no epidemiologic study to date has exami

75 The potentiation of neurite shortening by difopein in G2019S-LRRK2 neurons was rever

76 stent peritonitis cells showed reduced cell shortening, Ca transient amplitude and sarcoplasmic reti

77 icroM of KN93 prevented the decrease in cell shortening, Ca transient amplitude, and sarcoplasmic ret

78 f the hallmarks of aging, including telomere shortening, cellular senescence, activation of PI3 kinas

79 increase in young cells exposed to lifespan-shortening conditions or decrease in young cells exposed

80 to liquid oil, but they were harder than the shortening containing products.

81 es (extends) in-plane in one direction while shortening (converging) in the perpendicular in-plane di

82 munomodulating therapies may be effective in shortening corrected QT interval and reducing TdP recurr

83 Furthermore, progressive telomere shortening correlated with severity of disease, causing

84 season (during which time food is ample) and shortening critical development time (the period from th

85 imensions, ejection fraction, and fractional shortening) deteriorated in TNC-deficient mice compared

86 hancing surface thermodynamic contributions, shortening diffusion lengths, and increasing the number

87 for >/=80% of the final R-R and AH interval shortening during ablation.

88 nals are critical for the regulation of cell shortening during initial MHB formation.

89 t maintained translation despite tail-length shortening during oocyte maturation, and prevented essen

90 s that the Tianshan crust experienced strong shortening during the Cenozoic.

91 The QT-shortening effect of ranolazine remained effective throu

92 s, reduced ejection fraction, and fractional shortening (ejection fraction %, 54.76 +/- 0.67; fractio

93 d preserved ejection fraction and fractional shortening (ejection fraction %, 73.06 +/- 6.31; fractio

94 ndrial calcium uptake and dendritic/neuritic shortening elicited by mutant LRRK2, whereas expression

95 Since many life-shortening events are related to diseases, we developed

96 Critical telomere shortening (for example, secondary to partial telomerase

97 Left ventricular shortening fraction, ejection fraction, mass, and fracti

98 the photoluminescence) and carrier lifetime shortening (from approximately 18.3 +/- 0.8 to approxima

99 l measurements (calcium transient, sarcomere shortening) from isolated myocytes (n=42-104 myocytes pe

100 tal disorder characterized by mesomelic limb shortening, genital hypoplasia, and distinctive facial f

101 , as demonstrated by disease activity, colon shortening, histology, and elevated IL-6 and IL-5 in col

102 otors per half-myosin filament (n) during V0 shortening imposed either at the end of LR or at the pla

103 sed cardiac ejection fraction and fractional shortening in aged (24-month-old) mice and Ang II-infuse

104 eatment with BRD4 inhibitors caused telomere shortening in both mouse and human cells, suggesting BRD

105 tle is known about risk factors for telomere shortening in childhood.

106 some release and thereby influence flagellar shortening in Chlamydomonas.

107 ning oleogels for partial replacement of the shortening in cookies.

108 rodegenerative disease characterized by axon shortening in corticospinal motor neurons and progressiv

109 We report progressive telomere shortening in developing mouse cardiomyocytes after post

110 caused a 28.67% block of INaL and 12.57% APD shortening in experiments, while the model predicted 10.

111 ovide direct evidence for leukocyte telomere shortening in famine survivors.

112 and with a higher prevalence of postsystolic shortening in FGR as compared with controls.

113 verexpression (C1 (OE) ) in rice causes root shortening in high copper conditions and under iron defi

114 mass famine may be associated with telomere shortening in male descendants of famine survivors.

115 14-3-3theta overexpression reversed neurite shortening in neuronal cultures from BAC transgenic R144

116 Here, we demonstrate that telomere shortening in NOTCH1-haploinsufficient mice is sufficien

117 Significantly, 3' UTR shortening in S. pombe coordinates with up-regulation of

118 (2+) load, together with decreased sarcomere shortening in Slc26a6(-/)(-) cardiomyocytes.

119 from MgATP hydrolysis to generate force and shortening in striated muscle.

120 region (UTR) lengthening in head and 3' UTR shortening in testis, and characterize new tissue and de

121 dministrations showed visually detectable T1 shortening in the dentate nucleus (n = 13), globus palli

122 ac cycle and prematurely truncates sarcomere shortening in the facilitation of rapid relaxation.

123 reveal progressive, eastward steepening and shortening in the horizontal advance of the subducting I

124 ar Ca(2+) concentration ([Ca(2+)]i) and cell shortening induced by uterotonics, and this reversal eff

125 Telomere shortening induces chromosomal instability that, in the

126 This proliferation-independent telomere shortening is accompanied by an induction of a DNA damag

127 Abnormal telomere shortening is also described in cases of acquired aplast

128 Sheath shortening is associated with a low frequency of [Ca(2+)

129 Leucocyte telomere length (LTL) shortening is associated with cardiovascular ischemic ev

130 Their shortening is caused by inflammation and oxidative stres

131 n response to oxidative stress, and telomere shortening is correlated with reduced survival and life

132 rtening (range 30-80 nm per hs) and, when V0 shortening is imposed at the end of LR, n can be as low

133 g due to musculus syringealis ventralis (VS) shortening is intrinsically constraint at maximally 12%

134 Telomere shortening is proposed to be a primary molecular cause o

135 When V0 shortening is superimposed on the maximum isometric forc

136 Deadenylation, also called poly(A) tail shortening, is the first rate-limiting step in general c

137 ptimizing peritransplant conditions, such as shortening ischemic times with the use of thrombolytic d

138 increasing its polyubiquitination level and shortening its half-life from 24 h to approximately 3.5

139 1, negatively modulates beta-TrCP1 levels by shortening its protein half-life through promoting its u

140 mperatures (SST), hastening development, and shortening larval durations.

141 care by reducing unnecessary antibiotic use, shortening length of hospital stay, improving influenza

142 ians were blinded to results unless cervical shortening less than 15 mm was identified.

143 stolic dysfunction was defined as fractional shortening less than 25%.

144 uplift is potentially attributed to tectonic shortening, lithospheric delamination and unloading due

145 ysmorphisms, severe micrognathia, rhizomelic shortening, microcephalic dwarfism, and mild development

146 the linear phase quickened relaxation, while shortening movements prolonged the time course.

147 crobead, the force it could transduce from a shortening MT averaged 3-5 pN but could exceed 10 pN, id

148 ying CENP-F as a highly effective coupler to shortening MTs.

149 - to C-state does not occur, although during shortening muscle stiffness is reduced compared to the i

150 systolic peak strain, and mild post-systolic shortening (n = 35); and type III: systolic stretching w

151 systolic stretching with large post-systolic shortening (n = 37).

152 hed motors per half-thick filament during V0 shortening (n) is estimated by imposing, on tetanized si

153 de repeat disorders are severe, usually life-shortening, neurological disorders caused by nucleotide

154 telomere elongation rather than the telomere shortening observed in other telomeropathies.

155 In humans, telomere shortening occurs during aging, while inappropriate acti

156 One of the factors most contributory to the shortening of a surgeon's career is work-related pain an

157 One of the factors most contributory to the shortening of a surgeon's career is work-related pain an

158 10-100 micromol/L) produced more significant shortening of action potential durations in RA (from 290

159 vesicle and is regulated by force-generating shortening of active zone material macromolecules in dyn

160 l dysplasia characterized by fetal akinesia, shortening of all long bones, multiple contractures, rib

161 Optical shortening of cardiac action potentials may benefit path

162 s at AT-SR junctions and earlier, more rapid shortening of central sarcomeres.

163 genome-wide, but instead lead to a dramatic shortening of chromosome 12 that contains the large arra

164 ovitine or S-CR8 is accompanied by sustained shortening of cilia and a more normal epithelial phenoty

165 mary cilia formation, and caused significant shortening of cilia length in cells that did form cilia.

166 c disease progression and is associated with shortening of ciliary length as well as restoration of c

167 small interfering RNA results in significant shortening of ciliary length, similar to what we observe

168 d that main advantage of UAE is considerable shortening of extraction procedure with strong emphasis

169 e found that R recombinase benefits from the shortening of its C-terminus.

170 The possible factors associated with the shortening of lead time between ocean warm water volume

171 It is shown that the shortening of lead time is due to frequency increases of

172 the compression of morbidity, measured as a shortening of life expectancy with disability, an extens

173 APA-mediated shortening of NRAS and c-JUN was seen frequently, and th

174 The primary outcome was shortening of P100 latency delay on full-field, pattern-

175 ing pathway in which the formation and chain-shortening of polysulfide occur at early stage accompani

176 t conferred by the environment, leading to a shortening of red blood cell half-life.

177 The stem-zone loss is attributed to shortening of S phase and acceleration of cell cycle exi

178 through contractile mechanisms that involve shortening of sarcomeres along myofibrils.

179 The shortening of target sequences through use of two target

180 relative to a GaCu analogue, indicative of a shortening of taus.

181 ation to soluble TcO4(-)) resulted from both shortening of TcO2 chains during redox cycling and assoc

182 inhibition of cancer cell proliferation and shortening of telomere length.

183 Studies in rats have shown that the shortening of telomeres in key tissues plays an importan

184 xposure to famine is not associated with the shortening of telomeres in peripheral blood leukocytes a

185 Loss of telomerase activity results in shortening of telomeric DNA and eventually a specific G2

186 ger through the record, with a corresponding shortening of the 'winter' reprieve from warm temperatur

187 ACR expression allowed precisely controlled shortening of the action potential duration by switching

188 myocytes and embryonic zebrafish resulted in shortening of the atrial action potential duration, a ha

189 ng, the PAS domain contracts, resulting in a shortening of the C-terminal beta-strand.

190 Ca(2+)-induced shortening of the Ca(2+) switch helix changes solvent ac

191 Substantial shortening of the Ce horizontal lineN bond was observed

192 esulting decrease in SAP activity leads to a shortening of the cell proliferation period and reduced

193 ce of the UCNP donor revealed a considerable shortening of the donor lifetime as a clear hint for For

194 tially cleaved glycosidic bond, and a slight shortening of the endocyclic C1-O5 bond.

195 The tuning is the result of mechanical shortening of the helical pitch achieved by imposing a u

196 cluding growth retardation, disproportionate shortening of the limbs, round head, mid-face hypoplasia

197 ence of ribonucleotides induces a systematic shortening of the molecules, together with a decrease of

198 signals that are spectrally identifiable and shortening of the MRI relaxation times T 1 and [Formula:

199 , especially the tip of the nose, indicating shortening of the nose and upturning of the nose tip.

200 erally thought that decapping is preceded by shortening of the poly(A) tail to a length that can no l

201 lation of Shh signaling is associated with a shortening of the primary cilium length and with a reduc

202 patients, 7%), lack of elongation effect or shortening of the prosthesis (7 patients, 4.5%), prosthe

203 Significant shortening of the R-R interval (P=0.0009), Wenckebach cy

204 ng of the Si-O-Si dihedral angle rather than shortening of the Si-O bond, and consequently there is n

205 Facial retrusion, the proximodistal shortening of the snout and widening of the hard palate

206 of meiotic chromosome movement is caused by shortening of the spindle to bring poles in contact with

207 Consistent with shortening of the telomeric C strand, metaphase chromoso

208 ack of C-strand maintenance leads to gradual shortening of the telomeric dsDNA, similar to that obser

209 Kinesin-4-mediated shortening of these overlaps at the onset of cytokinesis

210 affects the magnitude of ktr following step shortening or ramp shortening.

211 at the tips of dendrite branches, leading to shortening or removal of dendrites.

212 ther such increases reflect substantial life shortening or short-term displacement of deaths (harvest

213 two possible steady-state velocities: rapid shortening or slow growth.

214 , global warming can disrupt connectivity by shortening potential dispersal pathways through changes

215 which indicated that selective poly(A)-tail shortening primarily specifies these changes.

216 Here, we show that substrate shortening progressively destabilizes the consecutive en

217 Besides shortening QTc interval, mexiletine caused a major reduc

218 The trabeculae were subjected to shortening ramps over a range of velocities and the exte

219 decreases progressively with the increase of shortening (range 30-80 nm per hs) and, when V0 shorteni

220 m [1-7] and can increase task efficiency via shortening reaction times and saving on neural tissue [8

221 ormation (n = 12); type II: delayed onset of shortening, reduced systolic peak strain, and mild post-

222 virals (DAAs) and the feasibility of further shortening regimens is unclear.

223 the northern part of the Lhasa terrane, is a shortening-related basin.

224 ered TB mortality by 3% (95% UR: 1%-6%), and shortening RR TB treatment from 20 to 6 mo reduced RR TB

225 ce had smaller but still substantial impact: shortening RS TB treatment duration from 6 to 2 mo lower

226 from croissants prepared with the respective shortenings, samples containing gelatinized wheat starch

227 ll, increased ejection fraction and fraction shortening, so as to inhibit HF at 2 weeks after TAC.

228 peak force (p < 0.001) and reduced fascicle shortening speed (p < 0.001).

229 progressively with shortening and, during V0 shortening starting at the end of LR, is 1-4.

230 nge of 0.15-0.275 nm(-1) was observed during shortening suggesting that an azimuthal Tpm movement fro

231 se was stronger during (more effortful) step shortening than during step lengthening.

232 rom female rats displayed greater fractional shortening than males, and female ARVMs and myofibrils t

233 rved a rarely observed process of acyl chain shortening that likely induces membrane thinning, along

234 ietary restrictions, saving endoscopies, and shortening the diagnostic process.

235 r than commercial Pd/C (0.72 A per mgPd), by shortening the distance between Pd and Ni active sites,

236 Among all the interventions, we find that shortening the duration between death and burial and imp

237 By shortening the duration of therapy from the currently re

238 Shortening the duration of treatment with HCV direct-act

239 ing embryo-splitting approach, we found that shortening the half-life of Cas9 in fertilized zygotes r

240 Our studies indicate that shortening the interval between boosts can yield abundan

241 We show in this study that shortening the intervals between boosting events to 2 wk

242 culated iFR (iFRmatlab) and iFR-like indexes shortening the length of the WFP by 50 and 100 ms (iFR-5

243 ng granulomas will be vital to improving and shortening the long course of TB treatment.

244 Shortening the neck-linker does not facilitate rear-head

245 hermal conductivity typically through either shortening the phonon mean free path or reducing the spe

246 shortened the breathing cycle by selectively shortening the post-inspiratory phase.

247 s to an in-frame deletion of 92 amino acids, shortening the protein from 209 to 117 residues.

248 increments less than 0.02 A correspondingly shortening the proton transfer pathway.

249 e acceptable up to a factor of 3.8x, thereby shortening the required breath-hold duration from 17.7 s

250 impeding exit from naive pluripotency and by shortening the S-G2/M phases.

251 Shortening the scan duration to 45 min provided similar

252 Shortening the time from health-care seeking to diagnosi

253 ogical response) for a primary endpoint, (2) shortening the time point for measuring the surrogate by

254 Shortening the time required to concentrate NAs and inte

255 e device offers the significant advantage of shortening the time to collect data by allowing simultan

256 ps and increasing throughput by dramatically shortening the time to obtain clonally expanded cell col

257 1b infection without cirrhosis are limited; shortening the treatment duration might reduce the burde

258 However, shortening the treatment duration to less than 8 weeks c

259 Shortening the work:recovery durations (16:32 s vs. 32:6

260 The size and the speed of the early rapid shortening (the isotonic working stroke) increase by red

261 surface and numerosity, whereas lengthening (shortening) the duration yielded under- (over-) estimati

262 During shortening, the myofibril stiffness was independent of d

263 Without shortening, the wider cell-plate membrane depositions ev

264 the sodium content of meat products without shortening their shelf-life.

265 king these outbreaks is an important tool in shortening them and developing strategies to prevent the

266 ctive study is required to determine whether shortening time to physical therapy evaluation and treat

267 nation, conversely, involves a striking cell shortening to form the typical short myelin cells of reg

268 y be capable of delivering further treatment shortening, to days rather than weeks, if combined with

269 Critical to improving TB-therapy is shortening treatment duration and increasing therapeutic

270 l therapy has failed, and the feasibility of shortening treatment duration.

271 ing transition from isometric contraction to shortening under low load.

272 nduces DNA damage at telomeres and telomeric shortening upon long-term chemical exposure in cultured

273 de preclinical proof-of-concept of treatment shortening using antibiotic+ABZ combinations to deliver

274 e) and provides novel insights into unloaded shortening velocities (declining with increasing slack l

275 orce-generating capabilities, faster maximum shortening velocities, and/or a difference in myosin hea

276 ric force-generating capabilities or maximum shortening velocities-as has long been suggested-but rat

277 Accordingly, the unloaded shortening velocity (V0 ) is already set at the end of l

278 its methacholine dose-response relationship, shortening velocity, and response to length oscillations

279 force (PO /CSA) and an increase in unloaded shortening velocity, which could be a result of both qua

280 ric force/cross-sectional area) and unloaded shortening velocity; (iii) myosin/actin ratio and myosin

281 delayed rectifier (IKs) channel critical for shortening ventricular action potentials during high bet

282 instability, alternating between growth and shortening via catastrophe and rescue events.

283 The mean left ventricular fractional shortening, wall thickness, and thickness-to-dimension r

284 the Wenckebach cycle length and AH interval shortening was 18.1+/-11% and 24.6+/-19%, respectively.

285 The total shortening was approximately 40% of the original length.

286 When the shortening was completely replaced with oleogel softer p

287 Surfactant chain shortening was coupled to an increased abundance of the

288 Furthermore, the myofibril stiffness during shortening was greater than that during stretching and t

289 Microbial enzymatic chain shortening was responsible for a shift in ethoxymer mole

290 some release during flagellar shortening and shortening was slowed.

291 One hydrogenated and one non-hydrogenated shortening were baked with isolated components of a croi

292 r whereas LV contractility and LV fractional shortening were higher when compared to the HAART-unexpo

293 hila homologue of JNK, exacerbated longevity shortening, whereas overexpression of Bsk extended lifes

294 ncreases in physiological tremor with muscle shortening - while successfully replicating the concomit

295 iments, while the model predicted 10.06% APD shortening with 29.33% block of INaL.

296 Results suggest that gradual replacement of shortening with oleogels may be a suitable approach for

297 On the other hand, partial replacement of shortening with oleogels provided much more acceptable d

298 s-depressed mean left ventricular fractional shortening z scores (-7.85+/-3.98 versus -9.06+/-3.89, P

299 Mean fractional shortening z scores measured 3.5 to 6.4 years after diag

300 ciated with left ventricular (LV) fractional shortening (z-score for difference = 1.07; p = 0.02) and