ライフサイエンスコーパス: shunting

1 id editing, stop codon leakage and ribosomal shunting.

2 5' portion of the mRNA were found to assist shunting.

3 nown elements of epsilon were not needed for shunting.

4 vements of Pao(2)/FIO(2) ratio and pulmonary shunting.

5 r the departure site, were not essential for shunting.

6 ged-1), and showed evidence of arteriovenous shunting.

7 the papilledema resolved with weight loss or shunting.

8 ittle evidence of internal ribosome entry or shunting.

9 hin the P-coding region were dispensable for shunting.

10 mmodation, nonlinear temporal summation, and shunting.

11 ging alone for detection of gastrointestinal shunting.

12 A SPECT when detecting extrahepatic arterial shunting.

13 on of delivery and detection of extrahepatic shunting.

14 e, we assessed the biosynthetic events after shunting.

15 he DHBV polymerase is initiated by ribosomal shunting.

16 ugh an alternate mechanism known as ribosome shunting.

17 sential for protein 100k to promote ribosome shunting.

18 tite leader, are both essential for ribosome shunting.

19 inical status and decreased interventricular shunting.

20 critical to promote a high level of ribosome shunting.

21 nown as internal ribosome entry and ribosome shunting.

22 ad to embryonic hemorrhage and arteriovenous shunting.

23 ere hypoxemia and significant intrapulmonary shunting.

24 bility of inhaled NO to reduce right-to-left shunting.

25 that synaptic input may operate primarily by shunting.

26 ase required venovenous bypass or portocaval shunting.

27 lly managed by portal or mesenteric-systemic shunting.

28 showed a well seated device without residual shunting.

29 had mild and two (3%) had moderate residual shunting.

30 capillaries and extensive arteriolar-venular shunting.

31 g the physiologic effects during interatrial shunting.

32 ere assigned to undergo ventriculoperitoneal shunting.

33 ry sensitive to detect even small degrees of shunting.

34 tsynaptic potential (EPSP) amplitude through shunting.

35 w, GFR, O2 consumption, and arteriovenous O2 shunting.

36 ty-three patients were treated with surgical shunting, 24 mesocaval and 19 mesoatrial.

37 zed, renal perfusion can only be improved by shunting a higher proportion of cardiac output to the ki

38 Using a simple model we show how shunting a proportion of the tunnelling current through

39 By shunting a small junction with the Josephson kinetic ind

40 rption by bile ducts results in cholehepatic shunting, a pathway that amplifies the canalicular osmot

41 ikely by interfering with AA cyclization and shunting AA to the LOX pathway under physiological condi

42 s, an atrial septal defect was produced, and shunting across the atrial septum was visualized.

43 depending on the direction and magnitude of shunting across the ventricular septal defect (VSD).

44 cular interaction also facilitates ribosomal shunting across two types of obstacles: an upstream AUG

45 was a significant decrease in left-to-right shunting after device implantation (P<0.001) and signifi

46 tension may present with or without reversed shunting and associated cyanosis (ie, Eisenmenger syndro

47 vein organization and to prevent abnormal AV shunting and AVM pathogenesis.

48 nslation by cap-dependent scanning, ribosome shunting and cap-independent internal ribosome entry.

49 ar septal defects with exclusive ventricular shunting and demonstrate that, contrary to current hypot

50 ial distributions for the assessment of lung shunting and extrahepatic uptake.

51 , particularly for the first few years after shunting and for patients of Child's class A or B or wit

52 The nonlinear interaction between shunting and I(M) has other important consequences.

53 ry for myelomeningocele reduced the need for shunting and improved motor outcomes at 30 months but wa

54 thromboembolism, dissection and intracardiac shunting and mass effect over adjacent cardiovascular st

55 H-015 significantly alleviated portosystemic shunting and mesenteric vascular density in BDL rats, bu

56 100k protein therefore promotes ribosome shunting and selective translation of viral mRNAs by bin

57 h, when coupled together, inhibit spikes via shunting and spike threshold accommodation.

58 atures of AVMs by P14, including abnormal AV shunting and tortuous vessels in the brain, intestine an

59 Both shunting and transplantation can result in a 5-year surv

60 s of BAVMs, including cerebral arteriovenous shunting and vessel enlargement, by 3 weeks of age and d

61 compartment is the result of porto-systemic shunting and/or blocked P4501A induction in Ahr(-/-) dam

62 PFO size, degree of shunting, and a coexisting hypercoagulable state may be

63 icoenteric arterial anatomy, hepatopulmonary shunting, and appropriate dosimetry considerations.

64 Breathing oxygen for 1 min reduced shunting, and breathing oxygen for 2 min eliminated shun

65 nternal ribosome entry site (IRES), ribosome shunting, and eIF4G enhancers.

66 ted with liver portal hypertension, vascular shunting, and portal fibrosis through unknown mechanisms

67 sheath fenestration and cerebrospinal fluid shunting are used in the pediatric population.

68 (MAA) scan quantification of intrapulmonary shunting as predictors for outcome after liver transplan

69 RW responses is not consistent with synaptic shunting as the main cause of the reduction of the EPSP

70 y used as a bridge to surgical portosystemic shunting, as well as liver transplantation, but may caus

71 ution of the effectiveness of vesicoamniotic shunting at 28 days.

72 roliferation by manipulation of intracardiac shunting at the atrial level.

73 on at the C13 AUG occurred through ribosomal shunting because translation from this codon was cap dep

74 AV shunting began promptly after Notch4* expression in endo

75 These observations are most consistent with shunting being directed by signals that act through an u

76 lar network show an enhancement of diffusive shunting between arterioles, venules and capillaries and

77 causes portal hypertension, porto-pulmonary shunting, bleeding from collateral bypass vessels, and e

78 it) surgery relieves aortic stenosis (AS) by shunting blood from the apex of the left ventricle to th

79 hibition via sodium channel inactivation and shunting but can evoke spikes under certain conditions.

80 nventional treatment is ventriculoperitoneal shunting, but surgeons are usually not immediately avail

81 gher in the fetuses receiving vesicoamniotic shunting, but the size and direction of the effect remai

82 We avoid unwanted charge current shunting by the low resistive NM layer utilizing the new

83 Exercise-induced right-to-left shunting can be detected by noninvasive, cardiopulmonary

84 ystem provide direct evidence that ribosomal shunting can be mediated by mRNA-rRNA base pairing, a fi

85 oelectric self-sensing system by integrating shunting circuitry into conventional sensors.

86 This GlyR-mediated shunting conductance is independent of the presynaptic s

87 cally relevant conditions showed that when a shunting conductance was activated in the proximal third

88 as an intercellular signal and that pyruvate shunting contributes to aerobic lactate production by as

89 nflux opens SK channels that provide a local shunting current to reduce the EPSP and promote rapid Mg

90 Functional changes include venous-venous shunting, delayed arteriovenous transit, and delayed or

91 current serves to regulate synaptic gain by shunting depolarizing potentials that can produce Ca2+-d

92 Increased membrane conductance, or shunting, does not simply reduce neuronal excitability.

93 e is not able to support the hypothesis that shunting during carotid artery surgery reduces the risk

94 cise testing despite increased right-to-left shunting during exercise.

95 DP-ribose) polymerase, which inhibits GAPDH, shunting early glycolytic intermediates into pathogenic

96 neurons, published ChloCs produced a strong shunting effect but also a small, yet significant depola

97 e cell's membrane conductance and thus had a shunting effect on GABA(A)R currents.

98 strongly inhibitory primarily because of its shunting effect.

99 ances from Renshaw inputs exert considerable shunting effects in motoneurons and reduce the frequency

100 ated chloride channels is mediated mainly by shunting effects, which exert optogenetic control much m

101 In addition, shunting efficiency was altered by stress and was greatl

102 gnancies randomly assigned to vesicoamniotic shunting, eight neonates survived to 28 days, compared w

103 exchange when right-to-left exercise-induced shunting (EIS) occurs.

104 ts of the mRNA as directed by cis-acting RNA shunting elements and trans-acting protein factors.

105 e during inhibition, which counters membrane shunting even at high frequencies at which IPSPs sum.

106 een June and October 2010, 25 thresher shark shunting events were analysed.

107 e receptors exert their inhibitory effect by shunting excitatory currents and by hyperpolarizing neur

108 espite this, GABA inhibits PG cell firing by shunting excitatory signals.

109 Most physicians prefer TIPS to surgical shunting for patients with poor hepatic reserve because

110 o assess the effectiveness of vesicoamniotic shunting for treatment of LUTO.

111 ent a normal physiologic adaptation to allow shunting from either systemic-to-pulmonary circulation (

112 ating increases in product may be due to APP shunting from the beta-secretase to the alpha-secretase

113 routes of GTN biotransformation ("metabolic shunting") from thiol nitrosation to heme nitrosylation.

114 greater than 50%, portal vein invasion, and shunting had confirmed association with high LSF at mult

115 Patients with intrapulmonary shunting had lower Pao2 than both patients with PFO and

116 For some mRNAs, shunting has been shown to require various mRNA elements

117 tions like stereotactic ventriculoperitoneal shunting have been found to be attractive alternatives.

118 h as transjugular intrahepatic portosystemic shunting, hemodialysis, and in some cases, liver transpl

119 saturation (indicating greater right-to-left shunting); higher transferrin iron saturation index; int

120 n this clinical trial of an energy-absorbing/shunting hip protector conducted in US nursing homes, we

121 4 for ETV-CPC and 2 for ventriculoperitoneal shunting; Hodges-Lehmann estimated difference, 0; 95% co

122 % CI, 1.03 to 1.11), and cerebrospinal fluid shunting (HR, 2.02; 95% CI, 1.07 to 3.78) were associate

123 th corticosteroids, antiparasitic drugs, and shunting if hydrocephalus is present.

124 ded valves and occurred without intracardiac shunting in 55% of this surgical series.

125 at adenovirus protein 100k promotes ribosome shunting in a tyrosine phosphorylation-dependent manner.

126 or eliminated exercise-induced arteriovenous shunting in all subjects at submaximal and in 4/7 subjec

127 g, and breathing oxygen for 2 min eliminated shunting in all subjects.

128 rly identical to those required for ribosome shunting in cauliflower mosaic virus RNA and are well co

129 h disclosed virtually complete portosystemic shunting in Fut2(-/-)(high) mice, discrete portosystemic

130 Fut2(-/-)(high) mice, discrete portosystemic shunting in Fut2(-/-)(low) mice, and no shunting in wt l

131 Prolonged systemic-to-pulmonary shunting in growing piglets induces PH with biventricula

132 rizing in OML interneurons but predominantly shunting in IML interneurons.

133 stratum lucidum inhibitory interneurons was shunting in nature across the entire developmental age r

134 size is the result of massive portosystemic shunting in null animals.

135 acy of therapeutic left-to-right interatrial shunting in patients with heart failure with reduced eje

136 septal myocardium, leading to left-to-right shunting in the form of ventricular septal defect and pa

137 es after ETV-CPC versus ventriculoperitoneal shunting in Ugandan infants with postinfectious hydrocep

138 emic shunting in Fut2(-/-)(low) mice, and no shunting in wt littermates.

139 anslation initiation referred to as ribosome shunting, in which 40S ribosomes bind the cap and bypass

140 One postulated mechanism involves ribosomal shunting, in which ribosomal subunits completely bypass

141 ested an 86% probability that vesicoamniotic shunting increased survival at 28 days and a 25% probabi

142 n a phase plane model and was explained by a shunting-induced increase in voltage threshold.

143 Motor nerves play the critical role of shunting information out of the CNS to targets in the pe

144 endritic excitation and a phasic perisomatic shunting inhibition delivered by interneurons, a subset

145 It has been suggested that the shunting inhibition evoked by visual stimulation is resp

146 to V1 from higher cortical areas results in shunting inhibition in V1 neurons, which changes the res

147 her increases in tonic GABAA conductance the shunting inhibition starts to dominate over excitatory a

148 ulting tonic conductance generates a form of shunting inhibition that is capable of altering cellular

149 Shunting inhibition via these receptors reduced N-methyl

150 of more proximal inhibitory inputs, favoring shunting inhibition, is not satisfied.

151 embrane conductance is also increased during shunting inhibition, which accompanies the classic GABAA

152 quencies of oscillations and the duration of shunting inhibition.

153 mV), and dampened excitatory potentials via shunting inhibition.

154 of other depolarizing events, could lead to shunting inhibition.

155 spiking was under the control of concurrent shunting inhibition.

156 f GABAergic events on membrane conductance ('shunting' inhibition) and membrane potential ('hyperpola

157 ls (ECs) have a hyper-glycolytic metabolism, shunting intermediates to nucleotide synthesis.

158 EPO produced in CHO cells can be improved by shunting intracellular CMP-Neu5Ac away from GSL biosynth

159 Hepcidin contributes to AI by shunting iron away from erythropoiesis and sequestering

160 Ribosome shunting is a poorly understood form of initiation in wh

161 Portacaval shunting is an option for controlling hemorrhage from th

162 sion casts and angiography demonstrated that shunting is consistent with the existence of a patent du

163 A molecular mechanism for ribosome shunting is described by which enhanced binding of eIF4G

164 rrespective of whether or not vesicoamniotic shunting is done.

165 Neither venovenous bypass nor portocaval shunting is necessary to perform the procedure, and modi

166 over, BA derivatives undergoing cholehepatic shunting may allow improved targeting to the bile ducts.

167 egenerative disorders in which benefits from shunting may be short-lived, with a consequently unfavor

168 mentarity to 18S rRNA suggests that ribosome shunting may involve either specific RNA structural feat

169 rrangement suggests that regulation of cIAP2 shunting may involve recruitment of RNA binding proteins

170 ta indicate that DHBV employs either a novel shunting mechanism or a major variation on one of the ch

171 re identified as a prelude to dissecting the shunting mechanism.

172 and facilitating glycolysis via a substrate shunting mechanism.

173 tions as a switch in optic lobe development, shunting Medea from the Dpp pathway to the Activin pathw

174 e of CB receptors, severity of portosystemic shunting, mesenteric vascular density, vascular endothel

175 s lost in FRET experiments and culminates in shunting migration in a fibrous fibronectin matrix.

176 that moths generate antioxidant potential by shunting nectar glucose to the pentose phosphate pathway

177 pers dealing with issues surrounding carotid shunting, no randomized controlled trials evaluating thi

178 Highly efficient shunting occurred when multiple Gtx elements were presen

179 be the molecular mechanism by which ribosome shunting occurs with high efficiency on adenovirus late

180 ermine whether there is a risk for excessive shunting of (90)Y-microspheres to the lungs; to detect e

181 ts suggest the importance of selenium in the shunting of AA metabolism toward the production of PGD(2

182 on transport is balanced out by paracellular shunting of acid/base.

183 seem to not take into account arterio-venous shunting of amino acids, which comprises approximately 8

184 The shunting of arachidonic acid to the PGI(2) precursor PGH

185 t ammonia accumulation that results from the shunting of arginine catabolism into alternative nitroge

186 cretin pretreatment) results in cholehepatic shunting of bile acids.

187 al types of atrial communications that allow shunting of blood between the systemic and the pulmonary

188 is unknown (i.e., arising either from active shunting of blood or passive steal).

189 ulature of a tumor, increasing the effective shunting of blood through its capillary bed.

190 s a consequence of both portal hypertension (shunting of blood through portosystemic collaterals) and

191 s a consequence of both portal hypertension (shunting of blood through portosystemic collaterals) and

192 s a consequence of both portal hypertension (shunting of blood through portosystemic collaterals) and

193 s a consequence of both portal hypertension (shunting of blood through portosystemic collaterals) and

194 rease of flow through the capillaries due to shunting of blood through the superficial layer, allowin

195 Here we show that the shunting of carbon metabolism toward the mitochondrial t

196 Hbr, likely resulting from a combination of shunting of CBV to the focus and decreased metabolic dem

197 conclusion, secretin stimulates cholehepatic shunting of conjugated bile acids and is associated with

198 deficit in synaptic potentiation arose from shunting of dendritic EPSPs and APs.

199 able to replicate the conductance-dependent shunting of dendritic potentials, but show that synaptic

200 enestration of the Fontan circuit allows for shunting of deoxygenated blood to the systemic circulati

201 een thought to result from long-term passive shunting of excess glucose through alternative metabolic

202 olysis and apoptosis (TIGAR), which promotes shunting of glucose-6-phosphate into the pentose phospha

203 es excellent mechanical stability, effective shunting of high separation currents, and ease of manufa

204 es excellent mechanical stability, effective shunting of high separation currents, and ease of manufa

205 al [3-(13)C]alanine, indicating preferential shunting of imported glucose away from storage and into

206 GDS-607, indicating that the pharmacological shunting of K-Ras into the geranylgeranylation pathway p

207 ide direct evidence for switchboard-mediated shunting of metabolic flux by measuring mRNA levels of t

208 (TAP) involved in antigen presentation, and shunting of newly assembled chains to lysosomes.

209 sed bile flow was attributed to cholehepatic shunting of norUDCA as well to the lack of micelles in b

210 metabolites were decreased, consistent with shunting of prostanoid biosynthesis toward PGE2 by coact

211 t decrease in neuronal input resistance, and shunting of PSPs; all effects are possibly attributable

212 -phase insulin secretion from beta-cells and shunting of substrates to nonmuscle tissues, collectivel

213 at ubiquitinated Tau inclusions arise due to shunting of Tau degradation toward a less efficient ubiq

214 with WT gain, and it can be attributed to a shunting of the cardiac potentials due to the low resist

215 t of ClC-3 in endosomal acidification by Cl- shunting of the interior-positive membrane potential cre

216 midal neurons during ripples is countered by shunting of the membrane and postripple silence is media

217 transcription or predicted to be involved in shunting on the basis of mechanisms documented in other

218 ion decreased in all patients independent of shunting or change in LV EDA.

219 disease by molecular mechanisms that enhance shunting or increase the relative accessibility the BACE

220 d of the mRNA and appeared to involve either shunting or reinitiation.

221 either globally (left-to-right intracardiac shunting) or from flow and volume diversion from lost or

222 ation, increase right-to-left intrapulmonary shunting, or impair the ability of inhaled NO to reduce

223 ation during sepsis or thyrotoxicosis, blood shunting, or reduced blood oxygen content/viscosity (Fig

224 s the need for surgical revision, portacaval shunting, or repeat transplantation.

225 vein invasion (P = .033), and arterioportal shunting (P < .001) were significantly associated with d

226 failure favored HGPCS, as did survival after shunting, particularly for the first few years after shu

227 irrefutably establishes a role for surgical shunting, particularly HGPCS.

228 We hypothesized that pulmonary arteriovenous shunting (PAVS) is normally present in fetal lungs and t

229 red with their WT counterparts, suggesting a shunting phenomenon within the arachidonic acid (AA) met

230 nvasion (present, absent), and arterioportal shunting (present, absent) were correlated with (99m)Tc-

231 regarding the efficacy of acetazolamide, CSF shunting procedures and cerebral transverse venous sinus

232 ed by percutaneous or surgical portasystemic shunting procedures.

233 This unique shunting profile is consistent with a peak expression of

234 changes occurred in parallel with pulmonary shunting, progressive decreases in Pao2/Fio2 ratio, and

235 Shunting promptly resumed upon breathing room air.

236 Routine, selective or no shunting protocols during carotid artery surgery remain

237 Portal-systemic shunting (PSS) is common in patients with cirrhosis and

238 , mesenteric vascular density, portosystemic shunting (PSS), intrahepatic angiogenesis, and fibrosis

239 y at 6 months was confirmed by left-to-right shunting (pulmonary/systemic flow ratio: 1.06 [SD 0.32]

240 several degrees of increased intrapulmonary shunting (QS/QT), assessing the impact of intra- and ext

241 Disrupting the CART complex results in shunting receptors to a slower recycling pathway that in

242 me entry site (IRES) initiation and ribosome shunting, rely on ribosomal protein S25 (RPS25).

243 This residue acts as a kinetic switch, shunting repair toward long-patch BER upon correct dCMP

244 A sequences were both mutated indicated that shunting required an intact complementary match.

245 neocortical neurons and a hyperpolarizing or shunting response in mature neocortical neurons.

246 llular property but a dynamic consequence of shunting resulting from electrical coupling.

247 s dominated by consequences of portosystemic shunting resulting in microcirculatory disturbances, mil

248 Hyperpolarization or shunting results from outward current produced by chlori

249 eotides upstream) in a region not scanned by shunting ribosomes.

250 Relevant intrapulmonary shunting seems to occur in lung regions with CT numbers

251 Molecules that undergo cholehepatic shunting should be powerful choleretics in humans.

252 Shunting significantly increased during exercise in pati

253 We conclude that by shunting substantial amounts of carbohydrate into urine,

254 The wide range we found in foramen ovale shunting suggests a degree of variability in the way blo

255 on disease usually treated by suboptimal CSF shunting techniques.

256 ediates translation exclusively via ribosome shunting that bypasses 62 uAUGs.

257 nsistent with the theory of distal dendritic shunting-that can regulate the robustness of sensory-evo

258 GDH) is the metabolic enzyme responsible for shunting the glycolytic intermediate 3-phosphoglycerate

259 chloride that are beyond merely electrically shunting the proton pump.

260 hese conditions, cells maintain viability by shunting the reaction through an aberrant recombinationa

261 put should suppress network activity through shunting; this prediction was supported by cell ablation

262 It is unknown whether right-to-left shunting through PFO increases during exercise impairing

263 synaptic input onto CA3 interneurons remains shunting throughout development.

264 at transjugular intrahepatic portal-systemic shunting (TIPS) may improve quality of life in patients

265 after transvenous intrahepatic portosystemic shunting (TIPS), and before/after yogurt treatment.

266 ted thrombolysis, transjugular portosystemic shunting (TIPS), and liver transplantation, has expanded

267 sis, transjugular intrahepatic portosystemic shunting (TIPS), and orthotopic liver transplantation (O

268 interatrial septal shunt device that allows shunting to reduce the left atrial pressure provides cli

269 to late failure but is also less likely than shunting to result in a reduction in ventricular size th

270 nal radiation therapy to detect extrahepatic shunting to the lung or the gastrointestinal tract.

271 ion of the Krebs cycle and enhanced pyruvate shunting toward the glycolytic pathway.

272 shift in the Bermuda High to the southeast, shunting tropical storms to the south of Florida into th

273 nfected rats and cultured astroglioma cells, shunting tryptophan degradation toward the production of

274 0] Hounsfield Units interval, which includes shunting units within less opacified lung regions.

275 aluation revealed the presence of paraportal shunting vessels, increased numbers of portal vascular s

276 aris closure was observed as well as dilated shunting vessels.

277 t guidewire snaring to perform portosystemic shunting via femoral access.

278 ensitivity for detection of gastrointestinal shunting was 25%, the specificity 87%, and the accuracy

279 maging modalities to detect extrahepatic MAA shunting was compared.

280 and gait measures before and 4 months after shunting was correlated with amyloid beta plaques, neuri

281 Portosystemic shunting was demonstrated by portal angiography, which d

282 Pulmonary arteriovenous shunting was detected by direct epicardial echocardiogra

283 Once significant arteriovenous shunting was documented (bubble score = 2), workload was

284 ng room air, FIO2 = 0.209) and arteriovenous shunting was evaluated using saline contrast echocardiog

285 Shunting was less efficient, however, when the multiple

286 Pulmonary arteriovenous shunting was not present in animals studied at four week

287 Shunting was often required to control raised ICP.

288 Intrahepatic lobe shunting was present on NMI in only 2.9% of the cases bu

289 Gastrointestinal shunting was revealed by planar imaging in 4, by SPECT i

290 in all patients except one, in whom trivial shunting was seen at 12-month follow-up.

291 In Protocol I, shunting was seen in all subjects at 120-300 W.

292 al survival rates at 1, 3, and 5 years after shunting were 83%, 78%, and 75%, respectively.

293 Resource consumption and survival after shunting were determined.

294 were mapped, and RNA elements important for shunting were identified as a prelude to dissecting the

295 the discontinuous ribosomal transfer during shunting were mapped, and RNA elements important for shu

296 sed profound blood vessel enlargement and AV shunting, which are hallmarks of AVM, and led to lethali

297 endoscopic ETV-CPC and ventriculoperitoneal shunting with regard to cognitive outcomes at 12 months.

298 R imaging demonstrated arterio-portal-venous shunting, with draining into the TIPS.

299 t with increased ASBT promoting cholehepatic shunting, with secretin pretreatment, we found TC induce

300 This shunting would disturb arterial PCO2 and H+ homeostasis