ライフサイエンスコーパス: shut down

1 omes stable at induced HSP70 genes that have shut down.

2 lied along with ParB, expression of lacZ was shut down.

3 Ag-L appears and HDV RNA synthesis begins to shut down.

4 ellular stress, cap-dependent translation is shut down.

5 from chromatin rapidly once transcription is shut down.

6 the active ES, correlated with transcription shut-down.

7 r 31 was used, the electron-transfer pathway shuts down.

8 E1 RNA depletion shut down 18 rRNA formation, without overaccumulation of

9 , for the first time, that RTS-based control shuts down a dangerous short-circuit event 3 times earli

10 they promptly inhibit neighbouring cells and shut down activity.

11 MPP+ shuts down aerobic oxidative phosphorylation and ETC-med

12 d to be displayed, indicating that they were shut down after detection.

13 during embryonic development, but it usually shuts down after birth.

14 ripts from a gene before its activity can be shut down and its chromatin reset to an inactive state.

15 ed drug dose-dependent, long-term blood flow shut down and tumor growth delay in the MCaIV tumor, gro

16 ming of the cold-induced FLC transcriptional shut-down and upregulation of FLC antisense transcripts,

17 even under the harsh conditions of start-up, shut-down, and/or hydrogen starvation.

18 gonists and antiandrogens, cannot completely shut down AR signaling.

19 However, the mechanisms leading to vascular shut-down are still unknown.

20 scribed during growth, and its transcription shut down as the cells approached stationary phase.

21 r ecosystem service of leguminous crops--was shut down at high nano-CeO(2) concentration.

22 Protein synthesis is globally shut down at late times postinfection in the baculovirus

23 lop in mice in which IFN-gamma expression is shut down at P16 do not.

24 p tumors, whereas if transgene expression is shut down at P16, the clinical symptoms and tumors progr

25 on from the mutagenized ptb promoter was not shut down at the end of exponential growth.

26 Ethylene production is shut down at the level of 1-aminocyclopropane-1-carboxyl

27 Further, the gating of the channel can shut down ATP flux completely while, simultaneously, all

28 e autoregulation (RPAR) loop is critical for shutting down ATP-consuming active potassium uptake to c

29 zation of azobenzene switching, while Cu(II) shuts down azobenzene isomerization.

30 ctivated during mitochondrial inhibition and shuts down biosynthetic processes to help conserve cellu

31 ular ischemia model in mice that selectively shuts down blood supply to the ipsilateral hippocampal f

32 stituent (R=tBu), this catalytic reaction is shut down, but the complex becomes active for aqueous el

33 lipid hydrolase, acid sphingomyelinase, was shut down by E11.

34 ent-ionization (RESI) channel, are virtually shut down by mid-IR fields.

35 ar antigen and DNA, but the activity was not shut down by Pol delta in accord with rapid association/

36 ated in a system where cross-presentation is shut down by pretreatment with CpG.

37 pathogen, but then, the NKT cell response is shut down by two mechanisms; apoptotic contraction and m

38 ectopic expression patterns and hence were "shut down" by the model.

39 ndfast sea ice produces enough resistance to shut down calving at the terminus.

40 romoting adipogenesis and lipogenesis and by shutting down catabolic processes such as lipolysis and

41 f the enzyme and induces a loop closure that shuts down catalysis at the active site.

42 ) even in the face of anergy protocol, which shut down CD40L expression in normal T cells.

43 broad EC protective functions by effectively shutting down cell death pathways initiated by inflammat

44 rapy regimens, these xenograft breast tumors shut down classic estrogen signaling and activate altern

45 attenuates the TGFbeta signaling pathway to shut down clusterin expression, thereby stimulating angi

46 mediated cleavage of complement C3b, thereby shutting down complement activation.

47 ed significant inhibition, and nitrification shut down completely with TBP addition.

48 supplemented with corn trypsin inhibitor (to shut down contact activation) was studied in well-plates

49 Like immunophilins, Shut-down contains an FK506-binding protein domain and a

50 The likely contaminant responsible for shutting down cross-presentation is peptidoglycan (PGN).

51 both impaired CUP1 induction and failure to shut down CUP1 normally.

52 eceptor promotes M2-polarization in order to shut-down deleterious immune responses and limit bystand

53 isplatin activates ATR, CHK1 and WEE1, which shut down DNA replication and attenuate cisplatin induce

54 Though many genes are shut down during diapause, others are specifically expre

55 CME is shut down during early mitosis, but the mechanism of thi

56 s continuously in non-dividing cells, but is shut down during mitosis, when clathrin concentrates at

57 tion of a long-chain phospholipid completely shuts down electron transfer.

58 shut-down encodes a novel Drosophila protein similar to

59 ne of reasoning suggests that bacteria might shut down endogenous fatty acid synthesis on the additio

60 nosa has evolved tight regulatory systems to shut down energy-expensive type III secretion apparatus

61 Thus, L. pneumophila can shut down ER-mitochondria communication through cleavage

62 -terminal kinase (JNK) phosphorylation while shutting down ERK1/2 and p38 phosphorylation.

63 OP1 provides a regulatory feedback loop that shuts down excessive inflammatory responses and thereby

64 is dependent upon its ability to completely shut down expression of its lytic genes during lysogenic

65 both on the non-recombining Y chromosome, to shut down expression of maladapted genes [3], and on the

66 ed with the same timing as those that either shut down expression prior to initiation or lacked expre

67 an erythrocyte, the developing erythroblast shuts down expression of most of its genes but preserves

68 aining NuRD complex plays a critical role in shutting down expression of specific synaptogenesis-rela

69 ic (D/DMga4) is completely inactive in vivo, shutting down expression of the Mga regulon.

70 of the mutant phenotypes can be recovered by shutting down FAF1 expression through the administration

71 S. Typhi of TviA, a regulatory protein that shuts down flagellin (FliC) expression when bacteria tra

72 t documents, but by 1967, it was effectively shut down following the refusal of journals to accept ar

73 Clonal analysis indicates that shut-down functions autonomously in the germline.

74 s; and (ii) addition of succinate reduced or shut down further expression of plcH in osmoprotectant-i

75 methylation alone might not be sufficient to shut down gene expression.

76 ional cloning approach, we have isolated the shut-down gene.

77 This process shuts down general protein synthesis to conserve amino a

78 might correspond to regulatory mechanisms to shut down glycolysis in a reverse, step-wise fashion in

79 Our study also reveals a novel mechanism of shutting down gp96 post-translationally in regulating it

80 Human adenoviruses (HAdVs) shut down host cellular cap-dependent mRNA translation w

81 . aeruginosa secreting ExoS, upon infection, shuts down host cell survival signal pathways by inhibit

82 ellular pathways that regulate apoptosis: it shuts down host cell survival signal pathways by inhibit

83 sport networks of small safe conduits and/or shutting down hydraulic function by dropping leaves duri

84 proper timing even when transcription is not shut down; i.e., mioC does not serve as a negative regul

85 iation of a "switched" Th1 population, which shuts down IFN-gamma secretion and upregulates IL-10 and

86 ly, IL-10-producing neutrophils specifically shut down IL-17A production by Th17 CD4 cells, but not I

87 s in anergic cells and may enable T cells to shut down IL-2 production selectively during anergy.

88 These Treg shut down IL10, gain potential to express IL17, and swit

89 echanism by which activated transcription is shut down in human cells.

90 ns (0.01% oxygen) DNA replication is rapidly shut down in immortalized mouse embryo fibroblasts.

91 Oceanic convection shut down in response to this flow, concentrating the en

92 s be tightly controlled to keep the response shut down in the absence of pheromone.

93 Retrograde transport was effectively shut down in this membrane-bound state, allowing for eff

94 ain (CTD), we find that oocyte transcription shuts down independently of maturation.

95 weak loss-of-function alleles confirms that shut-down is also required at later stages of oogenesis.

96 Here, we show that shut-down is essential for the normal function of the ge

97 bout 5 to 10 Myr ago, catastrophic slab loss shut down island-arc volcanic activity north of the Aleu

98 cts the TRP channel function so as to nearly shut down its activity.

99 subjected to degradation during apoptosis to shut down its signaling.

100 findings will help explain how L. heterotoma shuts down its hosts' immunity and shed light on the mol

101 tions become unfavorable in early autumn, it shuts down its reproductive axis, increases its body wei

102 orylation at S344 of MtCCaMK is adequate for shutting down its activity, and is epistatic over previo

103 f an interaction with lysozyme still fail to shut down late transcription and, remarkably, have becom

104 ovides a basis for eukaryotes to effectively shut down mature mRNA transport and thereby tailor prote

105 Our results suggest that shut-down may regulate germ cell divisions in the germar

106 lcyclopropane and ethephon revealed that the shut-down mechanism in ethylene biosynthesis is developm

107 ling tubercle bacilli to restrict growth and shut down metabolism in a coordinated fashion.

108 Under these conditions, where motility is shut down, microarray experiments showed an increased RN

109 , was not influenced by the time required to shut down mioC transcription, since the eclipse was the

110 Galphas promotes maturation of endosomes and shuts down mitogenic MAPK-ERK1/2 signals from endosomes.

111 translation in response to diverse stresses shut down most protein translation to conserve energy an

112 nding domains may be a general mechanism for shutting down motor protein activity and thereby regulat

113 tion, glucose starvation not only signals to shut down mTOR, but also results in the transient phosph

114 in dendritic cells serving to simultaneously shut down multiple pathways of inflammation.

115 on through depleting client oncoproteins and shutting down multiple oncogenic pathways.

116 alone in p53 negative tumors resulted in the shut down of angiogenesis and led to sustained tumor reg

117 of the tumor microenvironment including the shut down of angiogenesis and the induction of cellular

118 the p53-dependent induction of TSP-1 and the shut down of angiogenesis.

119 Stable shut down of miR-21, p47(phox) or STAT3 and overexpressi

120 tes that a fraction of tumour cells survives shut down of oncogenic signalling.

121 physiological changes occur that lead to the shut down of photosynthesis and a cessation of growth.

122 he Drosophila model of aggression, the acute shut down of the entire serotonergic system yields flies

123 ly due to the across-the-board, non-specific shut down of transcription in a condition of growth arre

124 at later times postinfection, likely due to shut down of transgene expression, and indicating that t

125 In animal tumors, it can cause the shut-down of blood flow, leading to extensive tumor cell

126 ould form a positive feedback loop for rapid shut-down of ceramide channels.

127 ance of origin activity and, consequently, a shut-down of plasmid replication under conditions of hig

128 ion (EHT) is a dynamic process involving the shutting down of endothelial gene expression and switchi

129 ation genes, but rather is important for the shutting down of the pluripotency network in differentia

130 s are driven toward the MS, and the field is shut down once the ions reach the vicinity of the MS inl

131 these organisms, equalization is achieved by shutting down one of the two X chromosomes in the somati

132 remain metabolically active, whereas others shut down or rely on anaerobic metabolism.

133 re activated intracellularly (PrfA 'ON') but shut down outside the host (PrfA 'OFF').

134 Lytic cycle reporter promoters were shut down over time, and long-term survival of neurons h

135 of the IDH mutation on intrinsic apoptosis, shuts down oxidative phosphorylation and reduces ATP lev

136 and rapidly moved to restore Pak1 levels by shutting down Pak1 shRNA expression through a methylatio

137 Thus, upon abrupt glucose depletion, yeast shuts down pathways consuming large amounts of energy, i

138 Once star formation has been shut down, perhaps during the quasar phase of rapid accr

139 duced starvation response can be reverted by shutting down polyP synthesis genetically or pharmacolog

140 d stress response pathways in bacteria, RelE shuts down protein synthesis by cleaving mRNA within the

141 elay, while pyrylium-like ether terminations shut down proton exchange.

142 es initiates immediately upon activation and shuts down quickly even in the continuous presence of th

143 ere, we demonstrate that RFS-1/RIP-1 acts by shutting down RAD-51 dissociation from ssDNA.

144 For example, it can be used to shut down radical pathways and to give access to aryl ca

145 Point mutations that disrupt the Y-Y dyad shut down radical transport.

146 motes NRP internalization, which effectively shuts down receptor-mediated signaling by a second ligan

147 d that during mitosis, when transcription is shut down, Runx2 selectively occupies target gene promot

148 Knock-down of either pathway shuts down SA biosynthesis and abrogates pathogen resist

149 w the replication of the virus to be quickly shut down should adverse effects be detected.

150 NeuAc), added to the media of cultured cells shuts down sialylation by a mechanism involving its intr

151 rylation, VEGF, or VEGFR2 are ineffective in shutting down signaling to ERK1/2.

152 e homolog as a repair template is regulated, shutting down simultaneously for both CO and noncrossove

153 inflammatory response has to be regulated or shut down so as to allow for the reestablishment of matr

154 that the Compound I (peroxidase) pathway is shut down, so that instead the reaction intermediate div

155 Surprisingly, Aire could be shut down soon thereafter and remain off for long period

156 hat the tropical terrestrial carbon sink may shut down sooner than current models suggest.

157 Many will shut down sooner.

158 flammatory cytokines and trophic factors, by shutting down STAT1/STAT5 signaling that mediate essenti

159 rations, favoring fast nutrient utilization, shutting down stress responses, and boosting growth.

160 ial immune responses to foreign antigens and shutting down such responses prematurely.

161 expressed on activated T cells and serves to shut down T-cell activation, culminating in T-cell death

162 s a minimal inhibitory potential required to shut down TF-initiated thrombin generation.

163 ressing the formation of H3+ and effectively shutting down that mode of cooling.

164 embly during DNA replication and the need to shut down the activating system under replication-stress

165 While AG is known to shut down the expression of the stem cell maintenance ge

166 Here we show that SA can directly shut down the expression of the vir regulon.

167 This process may completely shut down the gated injection.

168 d with impurities and other methods that can shut down the hydrogenation reactions are highlighted in

169 The objective of HSCT is to immediately shut down the immune response and allow the transplanted

170 sor or valve during infection to temporarily shut down the lymph node to further antigenic challenge.

171 the N-RPS19 interaction is a novel target to shut down the N-mediated translation strategy and hence

172 ssion and glycolysis, and IFN-gamma addition shut down the oxidative metabolism in SYL-infected mphis

173 ker studies demonstrated the ability of 3 to shut down the PI3K/Akt pathway and induce apoptosis in c

174 of Gravin, paraxial mesodermal cells fail to shut down the protrusive activity mediated by the Rho/RO

175 low rapid transfer to activated Galpha(q) to shut down the signal.

176 ed task-related signals, but also completely shut down the spontaneous activity within the IO, which

177 ntegrated stress response is able to rapidly shut down the synthesis of proteins in eukaryotic cells.

178 ectural elements to effectively condense and shut down the Xi.

179 d isomerization to the open merocyanine form shuts down the FRET process by efficient quenching of th

180 ids, a standard treatment of disease flares, shuts down the interferon signature, further supporting

181 The use of base shuts down the isomerization pathway and allows for the

182 m the environmental occurrence of P3N, which shuts down the Krebs cycle by inactivating succinate deh

183 R (PKR), a versatile antiviral host factor, shuts down the translation machinery upon activation in

184 ng RNAs (siRNAs) and evaluated the effect of shutting down the expression of these proteins on rotavi

185 It is generally believed that shutting down the kinase activity of BCR-ABL by imatinib

186 t contribute to decreasing DC activation and shutting down the production of pathogenic IL-23.

187 for achieving an effective HTP, is twofold: shutting down the radically induced chain-growth additio

188 These results suggest that shutting down the residual activity of the limbic-arousa

189 when the plant was operating to when it was shut down, the plant was found to contribute a large per

190 Activation of PLC can shut down their activity if it depletes the PIP(2) pool

191 no acids to the bacteroids, enabling them to shut down their ammonium assimilation.

192 ly directed cell migration, but they fail to shut down their protrusive behavior and undergo the norm

193 rine bone marrow-derived M2 macrophages also shut down their TIMP-1 expression and produced proMMP-9

194 tiation of human dendritic cells effectively shuts down their immunogenic pathways and implicates tra

195 g infection, HSV-1 has evolved mechanisms to shut down these responses to evade the proinflammatory c

196 hotochemical azide activation pathway can be shut down through coordination of the terminal azide lig

197 onally thought as a consequence of the brain shutting down to external inputs, it is now acknowledged

198 caused by an indirect mechanism: these cells shut down transcription in response to DNA damage, effec

199 er growth-limiting conditions, budding yeast shut down transcription of genes of the translation appa

200 immune responses, the egress process can be shut down transiently.

201 in eukaryotic mRNA decay that simultaneously shuts down translation initiation and activates mRNA deg

202 tant Ndel1 lacking key phosphorylation sites shut down transport completely, as did a dominant-negati

203 phenotype than Lis1 RNAi alone, essentially shutting down transport.

204 of lysogeny by binding to Mu operator DNA to shut down transposition.

205 age Mu establishes and maintains lysogeny by shutting down transposition functions needed for phage D

206 age Mu establishes and maintains lysogeny by shutting down transposition functions needed for phage D

207 as trbA, encoding a repressor which helps to shut down trbBp.

208 l phenomenon whereby flagellum production is shut down under conditions which turn on T-pilus formati

209 How caspase activity is restrained and shut down under such nonapoptotic conditions remains unk

210 not dependent on protein synthesis, which is shut down very early during apoptosis before caspase-3 a

211 Until now, the silencer element, which shuts down vimentin synthesis in selected tissues during

212 aureus colonization by producing a signal to shut down virulence.

213 This exchange process is completely shut down when [Cp2TiCH2CH(CD3)(SiMe3)](+) is used, sugg

214 When IFN-gamma expression is shut down with doxycycline at postnatal day 12 (P12), th

215 e conditions until the decarbonation factory shut down with the collision of Greater India with Asia