ライフサイエンスコーパス: shut off

1 is phosphorylated, and protein synthesis is shut off.

2 s activated raises the question of how it is shut off.

3 rylated and protein synthesis is prematurely shut off.

4 entual promoter eviction and transcriptional shut off.

5 but had no effect on the saturated response shut off.

6 ng infection, when host protein synthesis is shut off.

7 in no longer is required and the gene can be shut off.

8 rgo ringdown decays when the cavity input is shut off.

9 ssion of the inducible plasmid ccrM gene was shut off.

10 ormally limits the rate of phototransduction shut-off.

11 or a strain where expression of Myo1p can be shut-off.

12 l a specific stimulus commands a coordinated shut-off.

13 thogen and a paradigm for virus-induced host shut-off.

14 prA interaction with ComE altered competence shut-off.

15 ontrol loop model that is proposed to aid in shutting off ABA signal transduction, to counteract leak

16 receptors bind ethylene, their signaling is shut off, activating responses.

17 to neuronal cell death, indicating that the shut-off aerobic glycolysis is essential for neuronal su

18 the first few days of differentiation and is shut off after 1 to 2 weeks.

19 First, when receptor synthesis is shut off, akr1 delta cells retain the ability to mate lo

20 nces in the rates at which PAR1 and PAR4 are shut off allow thrombin to trigger intracellular signali

21 uption to enhance NMJ stability, and is then shut off allowing NMJ disassembly during persistent cyto

22 econd, signalling activities display a rapid shut off and a slower adaptation during which responsive

23 ation and rapidly declining when the origins shut off and neighboring promoters turn on.

24 activated cells, host DNA synthesis is then shut off and replaced with virus DNA synthesis.

25 phorylation and arrestin binding, transducin shut-off and calcium feedback has revealed their respect

26 of chromosomal intertwines, transcriptional shut-off and complete segregation of chromosomes.

27 roarray analysis revealed host transcription shut-off and identified three temporal classes of phage

28 hosphate-responsive element-binding protein) shut-off and nuclear accumulation of class IIa histone d

29 Fah does not execute host transcription shut-off and relies on host RNA polymerase (RNAP) sigma(

30 sing knockout mice with defects in rhodopsin shut-off and transducin signaling, we show that two diff

31 l differentiation, in which Tcf3 is normally shut off, and promote features of the follicle outer roo

32 ate decays, however, the enhanced back ET is shut off, and some of the re-excited electrons relocaliz

33 nic protein, and the subsequent inability to shut off angiogenesis.

34 Here, we describe a double-shut-off approach to deplete yeast cells of Toa1, the la

35 found to be maximal in exponential phase and shut off as the bacteria entered stationary phase, while

36 rains in which msbA synthesis is selectively shut off at 42 degreesC accumulate hexa-acylated lipid A

37 eraction and subvert the immune response are shut off at intermediate levels of CodY activity, while

38 there is a mechanism by which replication is shut off at late times after transfection, which may ref

39 n early event in viral infection and is then shut off at late times.

40 in early myeloid differentiation is abruptly shut off at the level of late progenitors/early differen

41 While normal B cells promptly shut off BCL6 when they exit the GC, many GC-derived B-c

42 n of replication, since it might normally be shut off before initiation, and never be limiting, even

43 ome replication, while mioC transcription is shut off before initiation.

44 l of GRK1 accelerated the dim flash response shut off but had no effect on the saturated response shu

45 The SRD has a GAGA tetraloop that is shut off by a Watson-Crick C2658 x G2663 pair.

46 In the dark, the activity of PDE6 is shut off by the inhibitory gamma subunit (Pgamma).

47 n accumulation can be cleared after promoter shut-off by a combination of autophagy and vacuolar prot

48 ucer and activator of transcription 3, TSP-1 shut-off by HGF/SF is prevented solely by inhibiting mit

49 -1) protein ICP27, which contributes to host shut-off by inhibiting pre-mRNA splicing, interacts with

50 Tetracycline can effectively shut off c-Jun overexpression and prevent EC apoptosis.

51 In addition to its role in shutting off cap-dependent host mRNA translation, L(pro)

52 During mitosis, transcription is shut off, chromatin condenses, and most transcription fa

53 to active, phosphorylated GPCRs and thereby shut off 'classical' signalling to G proteins, trigger i

54 ntraction coupling, and ideally this release shuts off completely between heartbeats.

55 es, and previous data suggest that SOCS3 may shut off cytokine activation at the early stages of live

56 ter anomaly was carried to the Labrador Sea, shutting off deep convection.

57 ve demonstrated that cellular translation is shut off during apoptosis; however, details of the mecha

58 shed the acceleration of saturated responses shut off during light adaptation.

59 LF delayed the time taken for these genes to shut off during recovery from heat shock.

60 s of a hormone-coupled molecular switch that shuts off earlier developmental programs to allow for la

61 vations suggest that the microcirculation is shut off early in severe sepsis, allowing the effects of

62 s coding for factors of host gene expression shut-off, enzymes of viral genome replication and expres

63 ha-P dephosphorylation, assessed by a kinase shut-off experiment, progressed normally in Sephin1-trea

64 of mature particles, as measured by promoter shut-off experiments, is normal in the absence of the Br

65 ranscription factor to a repressor form that shuts off expression of Shh target genes.

66 ne" diseases was the realization that merely shutting off expression of a disease-encoding transgene

67 apid loss of mating competence observed upon shutting off expression of a TLS mutant form of Kex2p (Y

68 ENO was then shut off for 15 min before start of treatment with inhal

69 of G protein signaling' (RGS proteins) help shut off G-protein-mediated signaling by GTPase activati

70 penicillamine (SNAP), a NO donor essentially shut off glucose uptake, and in hearts from ecNOS (+/-)

71 We found that after 1 or 3 weeks of shutting-off hAPP expression, the glomerular circuit was

72 The effects of protein density on response shut-off have not been reported.

73 Failure to shut off histone expression disrupts centromeric chromat

74 d 3C(pro), to process their polyproteins and shut off host cell activities detrimental to virus repli

75 We also show that the viruses fail to shut off host cell polypeptide production.

76 had no effect on the ability of the virus to shut off host cell protein synthesis but did affect viru

77 han MP-12 did in Vero E6 cells and failed to shut off host protein synthesis in Vero cells.

78 Influenza A virus (IAV) infection shuts off host cell gene expression at transcriptional a

79 protein of encephalomyocarditis virus (EMCV) shuts off host cell nucleocytoplasmic trafficking (NCT)

80 n of type I IFNs and IFN-stimulated genes by shutting off host cell macromolecular synthesis, which i

81 its host cell pre-mRNA splicing, effectively shutting off host cell protein synthesis.

82 r surface can respond to immune complexes by shutting off IL-12 biosynthesis, to prevent the Th1-type

83 rods and the acceleration of their response shut off in background light.

84 ld-type virus, whereas protein synthesis was shut off in cells infected with R5103 virus.

85 ssion of a GAL1 promoter-driven KEX2 gene is shut off in MAT(alpha) cells, the TGN becomes depleted o

86 ve cytokines, although IL-17A production was shut off in the course of the infection.

87 though protein synthesis was not prematurely shut off in the human neuroblastoma cell line SK-N-SH, g

88 o-, aphtho-, and enterovirus groups causes a shut-off in cap-dependent translation of cellular mRNAs

89 l arrestin is indispensable for rapid signal shut-off in rod photoreceptors.

90 Polyadenylation shut-off in such cells results in a nearly normal ratio

91 This rapid shut-off indicates that the system is reset by an active

92 Interestingly, while IL-2 production was shut off, inhibitory anti-CTLA-4 mAbs permitted inductio

93 vent negative feedback loops that ultimately shut off insulin-dependent glucose uptake in vivo.

94 Our results imply that picornavirus-induced shut-off is not due to an intrinsic inability of p100 to

95 This shut-off is thought to be mediated in part by the proteo

96 mediated conformational switch of HK853 that shuts off its phosphatase activity under acidic conditio

97 The delayed shut-off kinetics of ISG43 mRNA corresponded to an incre

98 Thus PAR4 signaling is shut off less rapidly than PAR1, probably due to differe

99 f these GTP-binding proteins is an efficient shut-off mechanism that ensures the decay of the signal.

100 To prevent toxic accumulation, rapid shut-off mechanisms are required.

101 levels of OTUD1 inhibit cancer stemness and shut off metastasis.

102 h of gp55 is produced during T4 infection to shut off middle transcription by direct competition with

103 tion of poly(A)- mRNAs after polyadenylation shut-off might result from an increase in the ratio of r

104 The failure by the PI replicons to shut off minus-strand synthesis was not due to some defe

105 This defect shuts off miR-198 expression in favor of sustained FSTL1

106 ith E. chaffeensis, respectively, which were shut off more rapidly than with LPS stimulation.

107 sis per activated receptor than PAR1 and was shut off more slowly than PAR1.

108 transport of Li ions, while the Li-based SEI shuts off Na-ion transport.

109 ld is predicted to decrease with time and to shut off naturally when the Moon recedes far enough from

110 EPEC barely elicits cytokine production and shuts off nuclear translocation of NF-kappaB p65.

111 recovery phase of phototransduction through shut off of GTP/Talpha-activated PDE.

112 luenza virus infection results in a dramatic shut-off of cellular protein synthesis that is concomita

113 The shut-off of flagellin synthesis in response to CF airway

114 pment (late schizogony), there was a general shut-off of gene expression, although a small set of gen

115 ation factor (eIF)-2 complex, resulting in a shut-off of general translation, induction of apoptosis,

116 deficient states, resulting in translational shut-off of global hepatic protein synthesis, including

117 of this cleavage correlates broadly with the shut-off of host cell protein synthesis in infected cell

118 e basal transcription factor THIIH to induce shut-off of host cell transcription.

119 Coliphage N4 infection leads to shut-off of host DNA replication without inhibition of h

120 due to their inability to prevent host-cell shut-off of protein synthesis caused by hyperphosphoryla

121 1alpha (PP1) and is required to prevent the shut-off of protein synthesis resulting from phosphoryla

122 and found that abd1-ts cells display a rapid shut-off of protein synthesis upon shift to the restrict

123 eIF-2alpha, that it has evolved to preclude shut-off of protein synthesis, and that GADD34 may have

124 ing that inhibition of NMD induces premature shut-off of TCR-beta rearrangement.

125 It is proposed that Ca(2+)-dependent shut-off of the On bipolar cell transduction current may

126 rther the role proteolysis of eIF4G plays in shut-off of translation, we altered the 2A cleavage site

127 eformed replicase, thereby resulting in slow shut-off of viral RNA synthesis.

128 d, little is known about how the systems are shut-off once the inducing stress has subsided, except t

129 t that is activated by this protocol rapidly shuts off, or desensitizes.

130 f Escherichia coli to uroepithelial cells is shut off outside the host at temperatures below 26 degre

131 tions, activated a general and dominant CREB shut-off pathway that blocked induction of BDNF expressi

132 at were treated with doxycycline for 3 weeks shut off Pdx1 expression, decreased insulin production,

133 Additionally, indomethacin, which shuts off PGE2 synthesis, and cAMP-blocking reagents fai

134 We show that TSP-1 shut-off plays an important, extrinsic role in HGF/SF-me

135 it can compensate for radiative cooling and shut off precipitation.

136 Using a galactose shut-off procedure, we determined that the half-life of

137 n often includes activation of pathways that shut off protein synthesis and thereby inhibit viral rep

138 In the reticulocyte lysate system the W RNAs shut off protein synthesis through an ability to activat

139 cking general-base capability in this pocket shuts off rescue.

140 As rhodopsin kinase works with arrestin in shutting off rhodopsin after it has been activated by a

141 AML1-ETO quickly shuts off scl expression, and restoration of scl express

142 scP mutant, or in an lcrG mutant effectively shut off secretion.

143 nct residues as the activator as well as the shut-off signal of Wnt/beta-catenin signaling and (ii) s

144 tion; however, the mechanisms of PAR1 signal shut off still remain unclear.

145 Of 177 selected conditional shut-off strains tested, the virulence of 102 was blocke

146 The liver, skin, and tail fibroblasts shut off tadpole genes and activate frog genes in the sa

147 tory system, growth arrest can be induced by shutting off Tag expression in the presence of Tc.

148 explain the ability of the alpha subunit to shut off the activity of the betagamma complex.

149 of the electrons in immediate contact pairs shut off the back electron transfer, whereas excitation

150 centrations of sodium dodecyl sulfate, which shut off the coalescence mechanism forcing ATPS formatio

151 3 are 87% identical, HSV-2 strains generally shut off the host more rapidly and completely than HSV-1

152 of this similarity, HSV-2 strains generally shut off the host more rapidly and completely than HSV-1

153 lizes kinetochore-microtubule attachments to shut off the spindle checkpoint, suggesting that cells r

154 hips that involved P binding to either G (to shut off the synthesis of P) or M (to stimulate its degr

155 The cold upper atmosphere shuts off the anticipated enhanced-Jeans, hydrodynamic-l

156 onstrated by the finding that angiopoietin-1 shuts off the expression of BMPR1A, a transmembrane prot

157 d a cell autonomous program that temporarily shuts off the insulin gene.

158 egative regulatory mechanism that ultimately shuts off the mating signal downstream of the receptor.

159 the AAA ATPases in the 19 S regulatory cap, shuts off the proteasome through the inhibition of ATPas

160 This system almost totally shuts off the reactions that form undesired CO and CO(2)

161 tical to control the differentiation program shutting off the c-Myc gene in large pre-B cells.

162 accelerating turnover of Mre11 at DNA ends, shutting off the DNA damage checkpoint and allowing cell

163 ding, NADP(+) bends and interacts with D317, shutting off the entrance to create a protected micro-en

164 (F) is sufficient to feminize XY germ cells, shutting off the expression of male-specific markers and

165 e and high quality printing while completely shutting off the nonilluminated counterparts.

166 intrinsic instability of Sda contributes to shutting off the pathway.

167 redistributed stress in southern California, shutting off the production of small earthquakes in some

168 Shutting off the promoter resulted in changes normally a

169 ctivated in the presence of immune complexes shut off their production of IL-12p70 and induced a Th2-

170 share an unexpected intrinsic mechanism for shutting off their action.

171 tly induced upon viral infection and rapidly shut off thereafter.

172 olved mechanisms to rapidly and specifically shut off these beneficial inflammatory activities before

173 A key switch in the hypothalamus shuts off this arousal system during sleep.

174 ssible Top10 promoter system to specifically shut off transcription of the Fed-1 transgene.

175 impaired the cell's ability to appropriately shut off transcription of the induced ARG1 gene, indicat

176 richia coli, gidA and dnaA transcription are shut off transiently after initiation of chromosome repl

177 cellular compartments where it is unable to shut off translation and repress viral replication.

178 low the replicase copying from the 3' end to shut off translation of upstream ORFs and free the RNA o

179 e idea that a ribosomal protein binds to and shuts off translation of ceruloplasmin mRNA.

180 ing host cell antiviral pathways that act by shutting off translation.

181 trfAp is very strong and shuts off trbAp activity until trfAp is inhibited by Kor

182 nts via interaction with RecA and competence shut-off via interaction with ComE, avoiding physiologic

183 ed these processes but subsequently acted to shut off viral gene expression and replication after the

184 age of a temperature-sensitive polymerase to shut off viral transcription, and we demonstrate that SI

185 expression had been induced and subsequently shut off were able to persist in vivo and reinitiate leu

186 ermits NO signalling, and this signalling is shut off when Hb alpha is reduced to the Fe(2+) state by

187 lity to nucleate microtubules is selectively shut off while maternal centrosomes remain competent to

188 cadBA expression was shut off within 4 min following a shift from acidic to n

189 osuppressed state with all Ty1-related genes shut off, without uncoordinated or mosaic expression in

190 cell division and the processes involved in shutting off YneA activity.

191 ctivation is a specific regulatory system to shut off zinc uptake activity in cells exposed to high e