ライフサイエンスコーパス: shutdown

1 ng the molecular mechanisms that mediate its shutdown.

2 tylation events correlate with induction and shutdown.

3 tive to PM extract acquired during the plant shutdown.

4 Severe TBI is associated with sustained shutdown.

5 on of the CME machinery does not account for shutdown.

6 near the outflow declined by 46% during the shutdown.

7 re significant again for those deployed post-shutdown.

8 romatin, resulting in global transcriptional shutdown.

9 drial dysfunction and the level of metabolic shutdown (analogous to a hibernation-type response), see

10 These data suggest that protein synthesis shutdown and apoptosis are separate responses of Ld652Y

11 ossible connection between protein synthesis shutdown and apoptosis, a series of recombinant AcMNPVs

12 Both groups exhibited renal shutdown and died in 57 hours or less.

13 virus, is able to preclude protein synthesis shutdown and ensure production of AcMNPV progeny in Ld65

14 -infected cells do not undergo translational shutdown and fail to establish an antiviral state during

15 35 was translated prior to protein synthesis shutdown and functioned to prevent apoptosis.

16 ing tumor vasculature, which causes vascular shutdown and leads to cancer cell death and necrosis.

17 nction at lower levels of primary production shutdown and possess a lower collapse threshold than Cam

18 gene expression patterns caused by a general shutdown and reprogramming of protein synthesis.

19 n a specific order, allowing for coordinated shutdown and subsequent reinstatement of photosynthesis.

20 e replenishment induces CSR2 transcriptional shutdown and switches Csr2 to an inactive, deubiquitylat

21 reactive oxygen species that cause vascular shutdown and tumor cell death.

22 response to transient operating conditions (shutdowns and startups).

23 esponse is accompanied by increased vascular shutdown, and erlotinib increases the in vitro cytotoxic

24 support corrosion during vehicle startup and shutdown, and platinum dissolution during vehicle accele

25 messenger RNA (mRNA) following transcription shutdown are linked by sharing the same sequence element

26 This signal leads to global translational shutdown, but it also enables translation of the transcr

27 ntly different for males deployed during the shutdown, but they were significant again for those depl

28 sts in an exaggerated CD4(+)Tem response and shutdown by apoptosis.

29 P(-) cell populations were isolated from the shutdown clones, they quickly reverted to the original d

30 Moreover, this shutdown could be closely coupled to fatty acid degradat

31 of pairs of pressure sensors for shutdown/no shutdown decisions, we apply a similar test to sensor pa

32 we conclude that endocytosis is temporarily shutdown during early mitosis.

33 HRF-1 prevented protein synthesis shutdown even when the cells were undergoing apoptosis,

34 n (BF) produced an initial transient network shutdown followed by diminished auditory responsiveness

35 nces recruit repressor machinery to actively shutdown gene expression.

36 The PKR-induced translational shutdown helps host cells to establish an antiviral stat

37 that inactivation of TolC triggers metabolic shutdown in E. coli cells grown in minimal glucose mediu

38 It causes reversible vascular shutdown in established tumors in vivo, consistent with

39 We also observed a mitochondria shutdown in infected cells and mitochondrial swelling in

40 d block both apoptosis and protein synthesis shutdown in Ld652Y cells infected with p35 mutant AcMNPV

41 lymph nodes (LNs), coupled with a transient shutdown in lymphocyte exit, results in dramatic cellula

42 When soils were dry, however, the shutdown in plant N uptake, along with the activation of

43 Profiles for males deployed pre-shutdown in receiving water were significantly different

44 eviously unknown mechanism for translational shutdown in response to viral infection and identify mTO

45 The VTAs cause a rapid shutdown in the blood supply to the tumor that kills tum

46 mg/kg i.p.) produced a preferential vascular shutdown in the tumor tissue at 2 and 6 h, leading to ma

47 othelial cells in vitro and induces vascular shutdown in tumor models in vivo.

48 eries, K(TdR) measurements showed a complete shutdown in tumor proliferation in patients in whom FDG

49 l tissue endothelia to induce acute vascular shutdown in tumors.

50 mutant AcMNPVs but not the protein synthesis shutdown in wild-type AcMNPV-infected Ld652Y cells.

51 the innate immune system are known to cause shutdown, including interferon alpha/beta (IFN-alpha/bet

52 rrosion induced during fuel cell startup and shutdown is a far more potent failure mode than platinum

53 Fibrinolysis shutdown is common postinjury and predicts poor outcomes

54 eat shock of p68 homozygotes, and hsp70 gene shutdown is delayed.

55 In this study, we show that the mitotic shutdown is due to an unmet requirement for actin in CME

56 till delayed in these mutants; however, CUP1 shutdown is normal.

57 The shutdown is not gradual: We describe a binary switch fro

58 This cellular shutdown is temporarily regulated, and during hypoxic ex

59 hese data indicate that CUP1 transcriptional shutdown, like induction, is an active process controlle

60 This shutdown may increase an organism's susceptibility to se

61 ranscriptionally by preventing translational shutdown mediated by the double-stranded RNA (dsRNA)-act

62 ing multiple periods (pre-, during, and post-shutdown) near the outflow for a wastewater treatment pl

63 to readings of pairs of pressure sensors for shutdown/no shutdown decisions, we apply a similar test

64 Rapid RNAP2 eviction, transcriptional shutdown, nucleosome invasion, and reduced transcription

65 olve the puzzle of the lack of translational shutdown observed in hantavirus-infected cells.

66 began a bold experiment involving the total shutdown of a 500-bed state hospital.

67 facultative heterochromatin), and the stable shutdown of a developmentally regulated gene (developmen

68 sed metabolomic study was conducted during a shutdown of a pulp and paper mill (PPM) to assess the im

69 rculosis (Mtb) is ensured by the coordinated shutdown of active metabolism through a broad transcript

70 nhances Ag presentation to T cells without a shutdown of Ag processing, allowing continued sampling o

71 We found that acute shutdown of all three D-cyclins in bone marrow of adult

72 Here we perturb the timing of the shutdown of Bicoid (Bcd)-dependent hunchback (hb) transc

73 d with the P/V-CPI(-) mutant show an overall shutdown of both host and viral translation at late time

74 Shutdown of CaCSE4 expression resulted in a sharp declin

75 M45 induces the degradation of NEMO and the shutdown of canonical NF-kappaB activation.

76 We observed rapid shutdown of carbon fixation in chloroplasts after SIPK/N

77 plicing followed by complete transcriptional shutdown of CD34.

78 ession of PS as a component of the regulated shutdown of cellular function that permits hibernating g

79 rs appear to be a component of the regulated shutdown of cellular functions that permits hibernating

80 n undifferentiated cells, SV induced a rapid shutdown of cellular protein synthesis and pE2 was effic

81 In differentiated cells, the SV-induced shutdown of cellular protein synthesis was transient and

82 Ubiquitous shutdown of cyclin D1 or inhibition of cyclin D-associat

83 we have traced this auxotrophy to a complete shutdown of cys-3+ gene expression.

84 eas increased RIP1 level leads to a complete shutdown of DNA damage-induced p53 induction by enhancin

85 Aptazyme-mediated shutdown of E1A expression translates into inhibition of

86 ong-standing paradigm in cell biology is the shutdown of endocytosis during mitosis.

87 n receptor at the cell surface, and not to a shutdown of endocytosis.

88 a decline of the ATP level and followed by a shutdown of energy-consuming processes.

89 he FLC locus and accelerates transcriptional shutdown of FLC during cold exposure.

90 on of cyclin kinase inhibitor activity and a shutdown of G1 kinase activity.

91 suggest that insect diapause is not merely a shutdown of gene expression but is a unique, development

92 ars to be ideally positioned to enable rapid shutdown of genes associated with metabolism and growth

93 The progressive shutdown of HIV transcription following infection sugges

94 of D10 synthesis correlates better with the shutdown of host gene expression, and deletion of this g

95 f host mRNAs, can contribute to the profound shutdown of host protein synthesis and blunting of antiv

96 s has previously been shown to result in the shutdown of host protein synthesis, cell rounding, and c

97 plicative lefs also abrogated AcMNPV-induced shutdown of host protein synthesis, suggesting that viru

98 ugh the CD4(+)CD8(+) stage involved a global shutdown of housekeeping genes that is rare among cells

99 Upon shutdown of Hoxb8 expression, near-unlimited numbers of

100 tential to differentiate into basophils upon shutdown of Hoxb8 expression.

101 lation of CD4(+) T cell apoptosis during the shutdown of immune responses is not fully understood.

102 pan was shortened, results suggesting that a shutdown of insulin signaling prompts activation of the

103 In particular, shutdown of interleukin 2 (IL-2) in the highly Th1 cell-

104 eappearance of an organized cytoskeleton and shutdown of K-Ras activity.

105 argeted inhibition of AEG1 might lead to the shutdown of key elemental characteristics of HCC and cou

106 e downregulation is not caused by the global shutdown of kinesin-1, as the ability of kinesin-1 to tr

107 o fundamental prerequisites is required: (i) shutdown of larval development by exposing larvae to low

108 Hypoxia (oxygen limitation) triggers the shutdown of major cellular processes, including gene exp

109 ent on either MET or EGFR combined to create shutdown of many programs vital to hepatocytes.

110 We conclude that the shutdown of membrane ion currents by elevated pi(o) is n

111 ection of PI cells with wt SFV triggered the shutdown of minus-strand synthesis, which we believe is

112 racellular retention or a global or specific shutdown of mRNA or protein synthesis.

113 a support the idea of a glacial weakening or shutdown of North Atlantic Deep Water production, wherea

114 ations do not necessarily require a complete shutdown of overturning.

115 cted much of Italy on 28 September 2003: the shutdown of power stations directly led to the failure o

116 During the shutdown of proliferation and onset of differentiation o

117 cient cells of each type have been produced, shutdown of proliferation and removal of excess cells.

118 le gene 153 (GADD153) that culminates in the shutdown of protein synthesis and apoptosis.

119 ond to viral infection and contribute to the shutdown of protein synthesis.

120 arm of this pathway results in the transient shutdown of protein translation, through phosphorylation

121 s can accumulate by Muller's ratchet after a shutdown of recombination, as in an evolving Y chromosom

122 hritis into end-stage disease coincides with shutdown of renal DNaseI expression in (NZBxNZW)F1 mice.

123 ad.RFC may clear PCNA from DNA to facilitate shutdown of replication in the face of DNA damage.

124 ional role of Rv1738 is to contribute to the shutdown of ribosomal protein synthesis during the onset

125 mutually exclusive relationship facilitates shutdown of sense FLC transcription in cis.

126 -level reconfiguration involving the partial shutdown of some but not all organs.

127 -modified lymphocytes persisted in vivo, the shutdown of TCR transgene expression was observed.

128 ls during the agonist-evoked response caused shutdown of the additional conductance; (iii) when appli

129 Snail2 knockdown, preventing transcriptional shutdown of the adhesion molecule Cad6b (Cadherin6b), th

130 ggests that, in order to ensure an effective shutdown of the apoptotic pathway, TNF induces multiple

131 rease in apoE expression was due to cellular shutdown of the cytomegalovirus promoter.

132 tiation, which is essential for the complete shutdown of the ESC gene expression program and the tran

133 olytic lymphocytes in general, may involve a shutdown of the genes for these proteins.

134 ions are associated with the nearly complete shutdown of the hydrological cycle.

135 arent body, capturing the decay and eventual shutdown of the magnetic field as core solidification co

136 ascribed to the aftermath of almost complete shutdown of the ocean ecosystems for millions of years d

137 nd in 2012-2015 coincided with the permanent shutdown of the reactors after the accident in 2011.

138 sponsive genes, thereby favoring a sustained shutdown of the synthesis of host cell proteins while th

139 cruitment could be responsible for a gradual shutdown of the undesirable Th2 arm of the immune respon

140 Shutdown of this translation mechanism might selectively

141 tiple phosphorylation targets for the global shutdown of transcription at mitosis.

142 sults indicated that an essentially complete shutdown of transcription occurs upon temperature shift

143 and double-stranded RNA and thus prevent the shutdown of translation by a mechanism that differs from

144 trinsic resistance of CTSL to stress-induced shutdown of translation.

145 Histology also confirmed shutdown of tumor vascular perfusion.

146 First, the long-term shutdown of tumour blood vessels by the anti-angiogenesi

147 through the FcR is not mediated by a global shutdown of tyrosine phosphorylation but is, rather, a s

148 atin condensation either by blocking mitotic shutdown of U1 and U2 snRNA transcription or by phenocop

149 actors from the promoter plays a role in the shutdown of U2 gene transcription in mitosis.

150 nd strength as well as realistic buildup and shutdown of wind burst activity in the western Pacific.

151 altering interactions between genes through shutdown or activation of pathways.

152 not undergo further testing because of case shutdown or insufficient sample quantity.

153 also guides the user through the startup and shutdown procedures, provides a continuous update on the

154 ining the CBF1 gene under the influence of a shutdown promoter (tetO-ScHOP) arrested their growth aft

155 ivirus-infected cells showed a wide range of shutdown rates, with the majority showing a 50% silencin

156 Stress induced-translational shutdown recruits the MSC to stress-granules, a depot fo

157 is involved in inducing a protein synthesis shutdown response in the absence of late viral gene expr

158 erfibrinolysis (HF; LY30 >/=3), fibrinolysis shutdown (SD; LY30 </=0.8), and normal (LY30 = 0.9-2.9)

159 A delayed shutdown specifically increases Bcd-activated hb levels,

160 n, suggesting that it provides an "emergency shutdown" system to regulate metabolism in response to d

161 slated into an extended period of lymph node shutdown, the induction of IFN-gamma-positive T cells, a

162 anti-angiogenesis agent, causing a vascular shutdown; the inner nanoparticle, which is trapped insid

163 on factor eIF2alpha and causes translational shutdown to create roadblocks for the synthesis of viral

164 prevents the PKR-induced host translational shutdown to ensure the continuous synthesis of viral pro

165 e thymocytes, increased apoptosis, or thymic shutdown to prevent tolerance to the pathogen from devel

166 or example, 3-season operation with a winter shutdown was favored to avoid high greenhouse gas emissi

167 However, the long-term vascular shutdown was mediated by thrombus formation, as evidence

168 HF without associated shutdown was not related to poor outcome, but extreme HF

169 ntrast, serine mutations in H2A prevent CUP1 shutdown when combined with spt10 deletions.

170 enotype also exhibited an exaggerated immune shutdown with heightened sensitivity to activation-induc

171 OTCH1 signaling in T-ALL induces a metabolic shutdown, with prominent inhibition of glutaminolysis an