ライフサイエンスコーパス: sialomucin

1 es a sulfated oligosaccharide carried by the sialomucins.

2 m selective metastasis of cells that produce sialomucins.

3 and podocalyxin comprise the CD34 family of sialomucins.

4 decrease in cell surface 9-O-acetylation of sialomucins.

5 des, O-linked chains carried on cell surface sialomucins.

6 The C2-O-sLe(X) motif occurs primarily on sialomucins and has been directly shown to contribute to

7 Thus, 9-O-acetylation on these sialomucins appears to be primarily regulated by the rat

8 rodimeric glycoprotein complex composed of a sialomucin ascites sialoglycoprotein (ASGP)-1 and a tran

9 ed expression of cell surface 9-O-acetylated sialomucins (but not the 9-O-acetylated ganglioside).

10 digestion with a glycoprotease that digests sialomucins, but no adhesion to cells that express selec

11 clonal antibody MECA-79 reacts with the PNAd sialomucins by recognizing an N-acetylglucosamine (GlcNA

12 These ligands consist of a complex of sialomucins, candidates for which are glycosylation- dep

13 The sialomucin CD34 is expressed on human and mouse hematopo

14 One such stem cell-associated antigen is the sialomucin CD34, a highly O-glycosylated cell surface gl

15 reported that MAb L11, against the leukocyte sialomucin CD43, blocks T-lymphocyte binding to lymph no

16 Muc4/Sialomucin complex (SMC) acts as an intramembrane ligand

17 Overexpression of the membrane mucin MUC4/Sialomucin complex (SMC) has been observed during malign

18 Muc4/sialomucin complex (SMC) is a heterodimeric glycoprotein

19 Sialomucin complex (SMC) is a large heterodimeric glycop

20 Sialomucin complex (SMC) is a large, heterodimeric glyco

21 Muc4/sialomucin complex (SMC) is a multifunctional glycoprote

22 mucin is considered as the homologue of rat sialomucin complex (SMC, rat Muc4) due to its similar st

23 Sialomucin complex (SMC, rat Muc4) is a heterodimeric gl

24 Sialomucin complex (SMC, rat Muc4) is a heterodimeric gl

25 Sialomucin complex (SMC, Rat Muc4) is a heterodimeric gl

26 Sialomucin complex (SMC, rat Muc4) is a membrane mucin i

27 munofluorescence staining was used to detect sialomucin complex in frozen sections and impression cyt

28 rmal growth factor, induce the expression of sialomucin complex in mammary epithelial cells.

29 These combined results indicate that sialomucin complex is a unique secreted product in the m

30 Because sialomucin complex is also present in the ocular tear fi

31 Sialomucin complex joins MUC1 as another membrane mucin

32 ent epitope on the mucin subunit (ASGP-1) of sialomucin complex occurs in a differentiation-dependent

33 n blot analysis assays were used to identify sialomucin complex RNA in ocular surface epithelia.

34 for carbohydrate and peptide epitopes on the sialomucin complex subunits.

35 Sialomucin complex transcripts were also detected in the

36 Sialomucin complex was immunoprecipitated from tear flui

37 Sialomucin complex was originally identified in rat mamm

38 Northern blot analyses were used to identify sialomucin complex/Muc4 (SMC/Muc4) mRNA in rat lacrimal

39 d peripheral node addressin (PNAd), a set of sialomucins displayed on high endothelial venules (HEVs)

40 nsin-180 contains 17 leucine-rich repeats, a sialomucin domain, an apparent transmembrane domain, and

41 re with the other family members including a sialomucin domain, but also possesses an extremely acidi

42 The sialomucin endolyn is a transmembrane protein with a uni

43 The sialomucin endolyn is implicated in adhesion, migration,

44 In this report, we show that CD43, a sialomucin expressed constitutively on T cells, can also

45 selectin glycoprotein ligand 1 (PSGL-1) is a sialomucin expressed on leukocytes that mediates neutrop

46 in ligand-1 (PSGL-1), a heavily glycosylated sialomucin expressed on most leukocytes, has dual functi

47 cantly increased levels of mRNA for CD164, a sialomucin found on human CD34+ hematopoietic stem cells

48 We show that purified neutrophil PSGL-1, a sialomucin glycoprotein that serves as a ligand for both

49 The L11 antigen is CD43, a sialomucin implicated in vitro in regulation of lymphocy

50 Antibodies to CD49f and PODXL, a sialomucin in the CD34 family, were the most robust for

51 to cells that express selectins that bind to sialomucin ligands could be detected.

52 teractions mediated by L-selectin binding to sialomucin ligands in high endothelial venules (HEVs).

53 ectin expressed on lymphocytes with sulfated sialomucin ligands such as CD34 and GlyCAM-1 on high end

54 We hypothesized that podoplanin, a sialomucin-like glycoprotein, increases the risk of VTE

55 mediated by binding of L-selectin to unknown sialomucin-like glycoproteins.

56 Both GD3.5 Ag and WC1 appeared to be sialomucin-like molecules that share similar O-sialoglyc

57 , indicating that it belongs to the class of sialomucin-like proteins.

58 ion into lymphoid tissues through binding to sialomucin-like receptors on the surface of high endothe

59 ll incompletely defined, they share a common sialomucin-like structure which is thought to present cl

60 P-selectin glycoprotein ligand-1 (PSGL-1), a sialomucin on human leukocytes, mediates rolling of leuk

61 nitor cells (HSPCs) express platelet-binding sialomucin P-selectin (CD162) and integrin Mac-1 (CD11b-

62 y and confirmed recently that podocalyxin, a sialomucin, plays a major role in maintaining the urinar

63 m that results in expression of glycosylated sialomucin proteins and the vesicle tethering and fusion

64 ning of neutrophils was diminished following sialomucin removal by O-glycoprotease, and its reactivit

65 differentiation of cultured myoblasts, (ii) sialomucins represent a class of potential effectors of

66 calyxin, and endoglycan comprise a family of sialomucins sharing both structural similarity and seque

67 an endopeptidase that selectively degrades O-sialomucins such as PSGL-1, abolished P-selectin but not

68 ) in total acidic mucins and in the ratio of sialomucin:sulfomucin (P = 0.0001).

69 D164 encodes a widely expressed cell surface sialomucin that has been implicated in regulation of cel

70 odocalyxin is an anti-adhesive transmembrane sialomucin that has been implicated in the development o

71 lyxin-like protein (PCLP) is a transmembrane sialomucin that is similar in structure to the well-char

72 CD164 is a cell surface sialomucin that is targeted to endosomes and lysosomes v

73 L-selectin on lymphocytes and PNAd, a set of sialomucins that are constitutively displayed on high en

74 se-dependent expression of this CD34-related sialomucin was discovered in Kit(+)CD71(high) proerythro

75 D34 and podocalyxin are structurally related sialomucins, which are expressed in multiple tissues inc

76 Furthermore, we show that GD3.5 and WC1 are sialomucins, which provides important clues to their fun

77 hepatic endothelial cells, and inhibition of sialomucin with antisense to the MUC2 gene inhibited adh