ライフサイエンスコーパス: sialoprotein

1 lating endopeptidase homolog), and Bsp (bone sialoprotein).

2 omologous to the cDNA sequence of rat dentin sialoprotein.

3 role in mediating the PTH induction of bone sialoprotein.

4 all as assessed by immunostaining for dentin sialoprotein.

5 -binding properties and bone tropism to bone sialoprotein.

6 n high levels of sialic acid similar to bone sialoprotein.

7 l10, osterix, alkaline phosphatase, and bone sialoprotein.

8 Bone sialoprotein accumulates within bone acidic glycoprotein

9 bone-associated proteins (osteopontin, bone sialoprotein, alkaline phosphatase, type I collagen) in

10 n gene confirms our finding that both dentin sialoprotein and dentin phosphoprotein are encoded by a

11 eened a mouse molar tooth library for dentin sialoprotein and dentin phosphoprotein cDNA clones.

12 support the previous suggestion that dentin sialoprotein and dentin phosphoprotein have distinct fun

13 dentin extracellular matrix proteins, dentin sialoprotein and dentin phosphoprotein, are expressed as

14 major noncollagenous dentin proteins, dentin sialoprotein and dentin phosphoprotein, are specific cle

15 Two dentin proteins, dentin sialoprotein and dentin phosphoprotein, have been shown

16 Dspp, and cleaved into two peptides, dentin sialoprotein and dentin phosphoprotein, that are localiz

17 two distinct extracellular proteins: dentin sialoprotein and dentin phosphoprotein.

18 o lead to a loss of function of both dentine sialoprotein and dentine phosphoprotein.

19 of osteoblastic differentiation (i.e., bone sialoprotein and osteocalcin) in the preosteoblasts, sug

20 sion of osteoblast marker genes such as bone sialoprotein and osteocalcin.

21 The bone matrix proteins dentin sialoprotein and osteopontin, but not transforming growt

22 cyte marker), while osteoblast markers, bone sialoprotein and osteopontin, remained unchanged.

23 ted that BMP-2 decreased mRNA levels of bone sialoprotein and type I collagen dose-dependently (10-30

24 reases in the expression of major bone (bone sialoprotein) and cartilage (type II collagen) matrix pr

25 rentiation markers such as osteocalcin, bone sialoprotein, and dentin matrix protein 1 (DMP1) was als

26 d with significant reductions in Runx2, bone sialoprotein, and osteocalcin expression, paralleled by

27 n markers Runx-2, alkaline phosphatase, bone sialoprotein, and osteocalcin.

28 nked glycoproteins) family of proteins, bone sialoprotein, and osteopontin, bound first to a cell sur

29 steogenic markers alkaline phosphatase, bone sialoprotein, and Runt-related transcription factor 2 re

30 NCPs were separated into osteopontin-, bone sialoprotein-, and dentin matrix protein-1-enriched frac

31 Surprisingly, osteocalcin and bone sialoprotein are also expressed by malignant but not nor

32 Osteocalcin and bone sialoprotein are the most abundant noncollagenous bone m

33 SPACR (sialoprotein associated with cones and rods), is the maj

34 ranscription factor 2 at 7 days and for bone sialoprotein at days 7 and 10 as well as higher OPN leve

35 that the Staphylococcus aureus MSCRAMM bone sialoprotein-binding protein (Bbp) might recognize host

36 e, exotoxin, Ser-Asp fibrinogen-binding bone sialoprotein-binding protein, fibrinogen and keratin-10

37 eonectin, whereas alkaline phosphatase, bone sialoprotein, bone Gla protein, and collagen II, all ind

38 Bone sialoprotein (BSP) and apatite co-localize in the extrac

39 BP and IGF promoted gene expression of bone sialoprotein (BSP) and OPN.

40 Bone sialoprotein (BSP) and osteocalcein (OCN) markers were u

41 B or TGF-beta resulted in a decrease in bone sialoprotein (BSP) and osteocalcin (OCN) mRNAs while PDG

42 u hybridization, for gene expression of bone sialoprotein (BSP) and osteocalcin (OCN), and histomorph

43 lendronate suppressed the expression of bone sialoprotein (BSP) and osteonectin in both femurs and bo

44 es associated with mineralized tissues, bone sialoprotein (BSP) and osteopontin (OPN), and a cell-sur

45 Bone sialoprotein (BSP) and osteopontin (OPN, ETA-1) are expr

46 l correlation between the expression of bone sialoprotein (BSP) and skeletal metastasis of breast can

47 tochemistry methods were used to detect bone sialoprotein (BSP) distribution in Hyp and WT mouse mola

48 y to determine the relationship between bone sialoprotein (BSP) expression and osteocalcin expression

49 rowth and enhanced osteocalcin (OC) and bone sialoprotein (BSP) gene expression in human prostate can

50 The bone sialoprotein (Bsp) gene provides an excellent model for

51 Expression of the bone sialoprotein (BSP) gene, a marker of bone formation, is

52 Bone sialoprotein (BSP) has been shown to induce limited gela

53 r phosphoproteins osteopontin (OPN) and bone sialoprotein (BSP) have been implicated in biological fu

54 d glycoproteins), osteopontin (OPN) and bone sialoprotein (BSP) in the Galnt1-null mice relative to t

55 Bone sialoprotein (BSP) is a multifunctional, highly phosphor

56 Bone sialoprotein (BSP) is a secreted glycophosphoprotein nor

57 Bone sialoprotein (BSP) is an acidic 301 amino acid protein e

58 Bone sialoprotein (BSP) is an acidic phosphoprotein with coll

59 Bone sialoprotein (BSP) is an extracellular matrix protein fo

60 cted in microdot cultures of UMR-106-01 Bone Sialoprotein (BSP) osteoblast cells.

61 ated proteins, i.e., osteopontin (OPN), bone sialoprotein (BSP), alkaline phosphatase (ALP), osteocal

62 g bone acidic glycoprotein-75 (BAG-75), bone sialoprotein (BSP), and alkaline phosphatase that are th

63 related transcription factor 2 (RunX2), bone sialoprotein (BSP), and osteocalcin (OCN) messenger RNA

64 Dentin matrix protein-1 (DMP1), bone sialoprotein (BSP), and osteopontin (OPN) are three SIBL

65 roteins: full-length osteopontin (OPN), bone sialoprotein (BSP), dentin matrix protein 1 (DMP1), dent

66 and expression of osteocalcin (OC) and bone sialoprotein (BSP), genes pivotal to bone matrix formati

67 f a mineralized tissue-specific marker, bone sialoprotein (BSP), indicating that epithelial products

68 s of mineral-associated genes including bone sialoprotein (BSP), OC, and osteopontin (OPN) in the cel

69 liferating cell nuclear antigen (PCNA), bone sialoprotein (BSP), osteocalcin (OCN), and tartrate-resi

70 mentoblast population (OC/CM) expressed bone sialoprotein (BSP), osteopontin (OPN), and OC, markers s

71 ted markers, e.g., osteocalcin (OCN) or bone sialoprotein (BSP).

72 containing the response element of rat bone sialoprotein (BSP).

73 entially expressed gene was found to be bone sialoprotein (Bsp).

74 this hypothesis, we infected 5-day-old bone sialoprotein (BSP)/avian retroviral receptor gene (TVA)

75 or core binding factor alpha-1 [Cbfa1], bone sialoprotein [BSP], osteocalcin [OCN], and osteopontin [

76 ne marrow mesenchymal stem cell, BMMSC; bone sialoprotein, BSP; hydroxyapatite/tricalcium phosphate,

77 integrin-binding phosphoglycoproteins (bone sialoprotein, BSP; osteopontin, OPN; and dentin matrix p

78 et genes, osteocalcin, osteopontin, and bone sialoprotein but did not significantly alter Runx2 level

79 rate that TCR-induced exclusion of the large sialoprotein CD43 from the synapse is an active event me

80 a significant decrease in expression of bone sialoprotein, characteristics of periodontal ligament in

81 entin sialophosphoprotein (DSPP) into dentin sialoprotein, dentin phosphoprotein, and dentin glycopro

82 Dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) are e

83 r matrix protein that is cleaved into dentin sialoprotein (DSP) and dentin phosphoprotein (DPP) with

84 Two acidic proteins, dentin sialoprotein (DSP) and dentin phosphoprotein (DPP), are

85 that is processed into two proteins: dentin sialoprotein (DSP) and dentin phosphoprotein (DPP).

86 two distinct proteins referred to as dentin sialoprotein (Dsp) and dentin phosphoprotein (Dpp).

87 ialophosphoprotein (DSPP) consists of dentin sialoprotein (DSP) and dentin phosphoprotein (DPP).

88 ly two structural/functional domains: dentin sialoprotein (DSP) and dentin phosphoprotein (DPP).

89 osphoprotein (DSPP) is processed into dentin sialoprotein (DSP) and dentin phosphoprotein.

90 Dentin sialoprotein (DSP) and phosphophoryn (PP) are the two no

91 Dentin sialoprotein (DSP) and phosphophoryn (PP) are two major

92 requires two highly acidic proteins, dentin sialoprotein (DSP) and phosphophoryn (PP).

93 Dentin sialoprotein (DSP) is a dentin extracellular matrix prot

94 Dentin sialoprotein (DSP) is a glycoprotein that is critical fo

95 Dentin sialoprotein (DSP) is essential for dentinogenesis and p

96 The expression of dentin sialoprotein (DSP) specifically marked dentin synthesis

97 alcin; and late markers like DMP2 and dentin sialoprotein (DSP) that are expressed by terminally diff

98 matrix protein that is processed into dentin sialoprotein (DSP), dentin glycoprotein (DGP) and dentin

99 ssion of dentin phosphoprotein (DPP), dentin sialoprotein (DSP), dentin matrix protein-1, and osteoca

100 chimeric protein composed of 3 parts: dentin sialoprotein (DSP), DPP, and dentin glycoprotein (DGP).

101 ssed by immunostaining for nestin and dentin sialoprotein (DSP).

102 nstream target genes such as DMP1 and dentin sialoprotein (DSP).

103 ntin phosphoprotein (DPP), generating dentin sialoprotein (DSP)/DGP and DPP.

104 llows: Dentin matrix protein (DMP-1), dentin sialoprotein (DSPP), and matrix extracellular phosphogly

105 2 preceded increases in osteocalcin and bone sialoprotein expression and this increase in Osf2 bindin

106 se results suggest that osteocalcin and bone sialoprotein expression is coordinated and regulated thr

107 y is to investigate how osteocalcin and bone sialoprotein expression is regulated in prostate cancer

108 teopontin and osteocalcin and decreased bone sialoprotein expression was detected within 7 days and m

109 itioned medium-mediated osteocalcin and bone sialoprotein gene expression in prostate cancer cells.

110 fferentiated MC4 cells, osteocalcin and bone sialoprotein gene expression were both down-regulated by

111 pment (e.g. Col1a1, Postn/Osf2, and the bone sialoprotein gene or BSP), genes that are expressed in t

112 scription factor in the osteocalcin and bone sialoprotein genes that cannot be resolved by traditiona

113 of osteoblast-specific osteocalcin and bone sialoprotein genes, alkaline phosphatase activity, and m

114 alkaline phosphatase, osteocalcin, and bone sialoprotein genes, and temporally associates with these

115 phosphoproteins such as osteopontin and bone sialoprotein have yielded important biological informati

116 ferentiation genes osterix (Sp7), Atf4, bone sialoprotein (Ibsp), and osteocalcin (Bglap) without aff

117 (DSPP), dentin matrix protein 1 (DMP1), bone sialoprotein II (IBSP), and bone morphogenetic proteins

118 phosphatase/ALPL, osteopontin/SPP1, and bone sialoprotein II/IBSP) in a subset of the hMSC population

119 n wild-type animals, the inclusion of dentin sialoprotein in the forming aprismatic enamel may accoun

120 osphatase), Ocn (osteocalcin), and Bsp (bone sialoprotein) in response to recombinant PP and stably t

121 teoblastic marker genes, namely Ocn and bone sialoprotein, in Atf4(-/-) developing bones.

122 ial protein, and those of pFv, an endogenous sialoprotein, involve binding interactions with overlapp

123 otein Fv (Fv binding protein (pFv)), a human sialoprotein involved in gut-associated immunity, have b

124 Bone sialoprotein is a 70-kDa extracellular matrix component

125 Bone sialoprotein is a major noncollagenous protein of bone.

126 Similar fragments of bone sialoprotein, like the intact protein, did not functiona

127 lcium deposition and gene expression of bone sialoprotein, lipoprotein lipase, and fatty acid binding

128 d osteocalcin mRNA levels and increased bone sialoprotein mRNA, consistent with an inhibition of term

129 increase in the steady-state levels of bone sialoprotein mRNAs within primary cultures of embryonic

130 (NEU1), promotes the interaction between the sialoprotein, mucin 1 (MUC1), and the opportunistic path

131 es in response to added native purified bone sialoprotein (nBSP) and its dephosphorylated form (dBSP)

132 a highly hydrophilic and negatively charged sialoprotein of approximately 298 amino acids that conta

133 a highly hydrophilic and negatively charged sialoprotein of approximately 298 amino acids with diver

134 Podocalyxin (PC), the major sialoprotein of glomerular epithelial cells (GECs), help

135 dontoblastic gene expression, such as dentin sialoprotein, on the untreated control resin was recover

136 enic animal approach we have extended dentin sialoprotein or dentin phosphoprotein expression through

137 us normal human valves for osteopontin, bone sialoprotein, osteocalcin, alkaline phosphatase, and the

138 d osterix-producing cells and increased bone sialoprotein, osteocalcin, and BMP-7 expression.

139 d increased mRNA levels of osteopontin, bone sialoprotein, osteocalcin, and Cbfa1 in the calcified va

140 llel, a decreased expression of Runx-2, bone sialoprotein, osteocalcin, and RANK-L.

141 c markers such as Runx2, Osterix, DMP1, Bone sialoprotein, Osteocalcin, NFATc1, and Schnurri-2, which

142 gand N-linked glycoproteins (SIBLINGs): bone sialoprotein, osteopontin, and dentin matrix protein 1,

143 onstrated that a sizeable proportion of bone sialoprotein particles were located within a 50-nm radiu

144 Plasma apolipoprotein (apo) E, a sialoprotein, plays an important role in reverse cholest

145 nd reduced sialylation of the major podocyte sialoprotein, podocalyxin.

146 revealed that (a) human osteocalcin and bone sialoprotein promoter activities in an androgen-independ

147 ed stimulation of human osteocalcin and bone sialoprotein promoter activities occurs through increase

148 s found to induce human osteocalcin and bone sialoprotein promoter activities via increased CRE/CRE-b

149 ased or repressed human osteocalcin and bone sialoprotein promoter activities.

150 osteoblast-specific element within the bone sialoprotein promoter and demonstrate its regulation by

151 etion analysis of human osteocalcin and bone sialoprotein promoter regions identified cyclic AMP (cAM

152 Overexpression of dentin sialoprotein results in an increased rate of enamel mine

153 ctin, type I collagen, osteopontin, and bone sialoprotein) showed any detectable effect on PG metabol

154 Bone sialoprotein specifically binds proMMP-2 and active MMP-

155 line phosphatase, bone Gla protein, and bone sialoprotein, suggesting an osteogenic phenotype.

156 1, and higher levels of osteopontin and bone sialoprotein than the normal.

157 kappaB ligand (RANKL), and integrins binding sialoprotein to be genes upregulated at the TB interface

158 potential interaction of MMP-20 with dentin sialoprotein was confirmed by coimmunoprecipitation and

159 n both genotypes, and the expression of bone sialoprotein was similar in tumor-bearing bones of both

160 Bone sialoprotein was the only osteoblast marker strongly ind

161 toblast-specific cDNA which codes for dentin sialoprotein, we discovered a 801-base pair open reading

162 To better regulate these sialoproteins, we asked whether endothelial cells (ECs)

163 rotein (BMP)-2, BMP-7, osteopontin, and bone sialoprotein were evaluated in alveolar sockets.

164 proteins, osteopontin, osteonectin, and bone sialoprotein, were identified in the protein extracts; t

165 actor 2), osteocalcin, osteopontin, and bone sialoprotein, were reduced proportionate to the reductio

166 pro-adhesive molecules osteopontin and bone sialoprotein, which is in contrast to the high levels of

167 Podocalyxin is a type 1 transmembrane sialoprotein with an N-terminal mucin-like domain.