ライフサイエンスコーパス: sialylated

1 retained the ability to bind fH when LOS was sialylated.

2 f polylactosamine alpha chains that could be sialylated.

3 s lipooligosaccharides (LOS) that are highly sialylated.

4 K(v)4.2, and K(v)4.3 were O-glycosylated and sialylated.

5 omplex, biantennary Fc glycan preferentially sialylated.

6 pooligosaccharide (LOS) molecule that can be sialylated.

7 l (RBC) surface receptors, many of which are sialylated.

8 anation for these findings is that levels of sialylated airway ligands for Siglec-F might be diminish

9 unotherapy in allergic patients also induced sialylated allergen-specific IgGs.

10 rmines that it binds to one or more alpha2,3-sialylated and alpha1,3-fucosylated glycan receptors tha

11 d glycine residues to interact with alpha2,3-sialylated and alpha1,3-fucosylated glycan receptors, in

12 on to and infection of neutrophils depend on sialylated and alpha1,3-fucosylated glycans.

13 Both sialylated and nonsialytated FetA bind to LPS, but only

14 ity to detect labile glycans such as heavily sialylated and polysialic acid N-glycans, which are diff

15 ine specificity of Siglec-8 toward different sialylated and sulfated carbohydrate ligands and determi

16 Purified mucin preparations carried sialylated and sulfated glycans, bound to eosinophils an

17 iety of either sulfated, sialylated, or both sialylated and sulfated glycopeptides.

18 that are expected to carry high densities of sialylated and sulfated O-linked glycans.

19 We demonstrate that H-ficolin is sialylated and that removal of sialic acid abrogates IAV

20 We generated one highly sialylated and two distinct more galactosylated 6-19 IgG

21 ctive species of Panx3, likely glycosylated, sialylated, and phosphorylated, was highly expressed in

22 structural variants, including high mannose, sialylated, and terminal galactosylated species were stu

23 coprotein ligand-1 (PSGL-1) and the alpha2,3-sialylated- and alpha1,3-fucosylated-moiety sialyl-Lewis

24 Two strategies for installation of sialylated antennae are explored, and both approaches co

25 gen-specific: only T cells responsive to the sialylated antigen become tolerized.

26 Exposure of B cells to sialylated antigens results in the inhibition of key ste

27 The ability of sialylated antigens to inhibit BCR signaling through tra

28 onstrating that immune complexes composed of sialylated antihemagglutinin antibodies and seasonal ina

29 and desialylated A2HSG, and depleted in mono-sialylated ApoC-III (ApoC-III1).

30 ents were enriched in SAA, LBP, ApoC-III, di-sialylated ApoC-III (ApoC-III2) and desialylated A2HSG.

31 an also be engaged by two potentially lethal sialylated bacterial pathogens of newborns and infants,

32 y to unsialylated, as compared with alpha2-6-sialylated, beta1 integrins.

33 One group represents sialylated biantennary compounds with an N-glycan core t

34 with mass spectrometry and found to contain sialylated biantennary structures.

35 to 2,6-sialylated Fc compared with similarly sialylated, biantennary glycoproteins, thus suggesting t

36 typic Malawian diet with or without purified sialylated bovine milk oligosaccharides (S-BMO).

37 taining fluorophore at the reducing end were sialylated by a one-pot three-enzyme system to generate

38 een the TGN and the plasma membrane, was not sialylated by a sialyltransferase at the TGN and that th

39 e may explain the increased pathogenicity of sialylated C. jejuni and may be key to the initiation of

40 s CD14, and the amplified response of DCs to sialylated C. jejuni LOS is CD14 dependent.

41 lpha and IFN-beta responses to i.v.-injected sialylated C. jejuni.

42 of Sn showed greatly reduced phagocytosis of sialylated C. jejuni.

43 cterial survival are also facilitated by GBS sialylated capsular polysaccharide interactions with Sig

44 The sialylated capsular polysaccharide of group B Streptococ

45 Many CTCs express sialylated carbohydrate ligands on their surfaces that a

46 e demonstrate that JCPyV can engage numerous sialylated carbohydrate receptors.

47 B mediates high-affinity binding to distinct sialylated carbohydrate structures on human platelets an

48 Siglec-5 (CD170) and its complexes with two sialylated carbohydrates.

49 n of increased surface expression of several sialylated cell adhesion molecules, including the known

50 evealed that Siglec-8 is partially masked by sialylated cis ligands.

51 P1 of HPyV6 and HPyV7 does not interact with sialylated compounds in solution or on cultured human ce

52 tional analysis revealed that binding to all sialylated compounds was mediated by the C-terminal bind

53 s ST6Gal-I and ST6GalNAc-I, forming alpha2,6-sialylated compounds.

54 rm that was characterized by the presence of sialylated core 1 and core 2 O-glycans.

55 e CHO cells is glycosylated with the typical sialylated core 1 structure.

56 Furthermore, for the generation of sialylated core 1 structures constructs encoding human p

57 anA, is required for S. pneumoniae to cleave sialylated core-1 O-linked glycans.

58 ted with gonococcal Por1B was similar to the sialylated counterpart only in the presence of higher (2

59 ts of eukaryotic plasma membranes, and their sialylated derivatives, gangliosides, are the major clas

60 rvation of an effective survival factor, the sialylated exopolysaccharide capsule.

61 This alpha2,6-sialylated Fc (sFc) has been reported to bind to the car

62 onstrate that it preferentially binds to 2,6-sialylated Fc compared with similarly sialylated, biante

63 ed the anti-inflammatory activity of IVIG or sialylated Fc fragments.

64 G subclass and Fc glycans, with abundance of sialylated Fc glycans (sFc) predicting quality of vaccin

65 eering of the IVIG's Fc glycans into a fully sialylated Fc glycoform, which may possess significantly

66 unctional P1 promoter, was unable to produce sialylated Fc in the systemic circulation, despite the p

67 parison of the structures of asialylated Fc, sialylated Fc, and F241A Fc, a mutant that displays incr

68 s identify an antibody receptor specific for sialylated Fc, and present the initial step that is trig

69 We now demonstrate that these sialylated Fcs require a specific C-type lectin, SIGN-R1

70 inflammatory status, pretreatment levels of sialylated FetA in the blood are indicative of the likel

71 y reveals that high levels of O-glycosylated sialylated FetA isoforms are found in patients exhibitin

72 Sialylated forms of the Fc fragment of immunoglobulin G,

73 odies made by p individuals recognize x2 and sialylated forms of x2, whereas x2 is lacking on P-defic

74 portion of antiproliferative factor (APF), a sialylated frizzled-8 related glycopeptide that inhibits

75 A lectin panel, distinguishing normally sialylated from hyposialylated glycans, used WGA, SNA, P

76 ecies, identifying CE peaks corresponding to sialylated (G1 + NANA, G2 + NANA), afucosylated (G0-GlcN

77 in which preferentially recognizes alpha-2,6 sialylated galactosides showed strong binding reactivity

78 on from Lewis(x)-type structures in mESCs to sialylated Galbeta1,3GalNAc-type glycans on differentiat

79 ialic acid precursor analogs to modulate the sialylated ganglioside-dependent interaction of MLV part

80 alylated PrP(C) contained greater amounts of sialylated gangliosides and cholesterol than membrane ra

81 ins mediate attachment of bacterial cells to sialylated gangliosides on the platelet cell surface.

82 PyV can both engage LSTc as well as multiple sialylated gangliosides.

83 mutation on HA resulted in a mixed alpha2-3 sialylated glycan (alpha2-3)/alpha2-6 binding virus (NY1

84 lutinin (HA) to long (chain length) alpha2-6 sialylated glycan (alpha2-6) receptors on the human uppe

85 Composed of a sialylated glycan attached to a ceramide lipid, the same

86 O) structure, we show ABH antigens stabilize sialylated glycan clusters on erythrocyte membranes uniq

87 ies on sialic acid recognition using a novel sialylated glycan microarray containing modified sialic

88 Our results demonstrate the utility of this sialylated glycan microarray to investigate the biologic

89 f its B subunit, PltB, with specific lumenal sialylated glycan packaging receptors.

90 Crystal structures of EV-D68 in complex with sialylated glycan receptor analogues show that they bind

91 pecificity of the viral hemagglutinin to the sialylated glycan receptors (in the human host) by use o

92 on surfaces, obstructing a groove that binds sialylated glycan receptors in many other polyomaviruses

93 stability and ionization bias experienced by sialylated glycan species.

94 Campylobacter jejuni expressing a GD1a-like, sialylated glycan.

95 itative binding affinity of HA to alpha2-->6 sialylated glycans (human receptors) is one of the impor

96 inding, with Gal-8N recognizing sulfated and sialylated glycans and Gal-8C recognizing blood group an

97 --enables specific binding of HA to alpha2-6 sialylated glycans and that recognition of this topology

98 Sialylated glycans are found at elevated levels in many

99 Single-cell binding studies indicate that sialylated glycans are likely not required for initial a

100 Sialylated glycans are synthesized in mammals by a singl

101 glec) family that recognizes alpha2-6-linked sialylated glycans as ligands.

102 tissues and highlight a functional role for sialylated glycans as reovirus coreceptors in the CNS.

103 IL-6 secretion were enriched in ApoC-III, di-sialylated glycans at multiple A1AT glycosylation sites

104 Two sialylated glycans bearing N-acetylneuraminic acid were

105 ot only result in accurate identification of sialylated glycans but also improve the characterization

106 ows for linkage specific characterization of sialylated glycans directly from the precursor mass but

107 Hemagglutinin (HA) binds to sialylated glycans exposed on the host cell surface in t

108 irus (IBV), require specific alpha2,3-linked sialylated glycans for attachment and entry.

109 Surprisingly, Gal6S is undetectable in sialylated glycans from eosinophils and BAL fluid analyz

110 me, fluorescence and radionuclide imaging of sialylated glycans in a murine tumor model in vivo.

111 ring 3F-NeuAc to mice dramatically decreases sialylated glycans in cells of all tissues tested, inclu

112 NAc), were incorporated into fucosylated and sialylated glycans in several cancer cell lines, allowin

113 MS analysis of sialylated glycans is challenging due to their low ioniz

114 The analysis of sialylated glycans is critical for understanding the rol

115 icity depends on toxin binding to terminally sialylated glycans on surface glycoproteins.

116 lutinin, and Sambucus nigra agglutinin) with sialylated glycans on the same cell surface.

117 Sialylated glycans on the surface of mammalian cells act

118 Binding of sialylated glycans or other ligands triggers signals tha

119 In vertebrates, sialylated glycans participate in a wide range of biolog

120 s in ionization efficiency among neutral and sialylated glycans prevent direct quantitative compariso

121 dulated by HopZ, including hopP, which binds sialylated glycans produced by GEPs in vivo.

122 in the expression of truncated core 1-based sialylated glycans rather than the core 2-based glycans

123 array approach to analyze the repertoire of sialylated glycans recognized by viruses from the same c

124 ed from the aqueous phase, while neutral and sialylated glycans remained in the DCM phase.

125 Sialylated glycans serve as cell surface attachment fact

126 DRAG), to quantitatively compare neutral and sialylated glycans simultaneously by MALDI-MS.

127 binding to sialyl Lewis x (sLe(x)) and other sialylated glycans that decorate P selectin glycoprotein

128 tested preferentially utilize NeuAcalpha2-6-sialylated glycans to infect SRECs.

129 However, quantification of sialylated glycans using MS is not as reliable because o

130 tiates viral entry by engaging host receptor sialylated glycans via its receptor-binding site (RBS).

131 and alkaline BGE systems, the mobilities of sialylated glycans were shifted relative to nonsialylate

132 ly, we used a nonmetabolic approach to label sialylated glycans with an independent chemistry, enabli

133 viruses, specifically bind to long alpha2-6 sialylated glycans with this topology.

134 for simultaneous profiling both neutral and sialylated glycans without derivatization or labeling.

135 sialylated glycans) to human-like (alpha2-6 sialylated glycans) receptors is believed to be associat

136 hemagglutinin (HA) from avian-like (alpha2-3 sialylated glycans) to human-like (alpha2-6 sialylated g

137 ereas Gal-1 bound alpha2-3- but not alpha2-6-sialylated glycans, and Gal-3 bound to some glycans term

138 high-mannose glycans, fucolsylated glycans, sialylated glycans, and hybrid structures were studied.

139 2)v showed a predominant binding to alpha2-6-sialylated glycans, similar to human-adapted influenza A

140 which bound almost exclusively to alpha-2,6 sialylated glycans, the seal H3 bound preferentially to

141 -R1 has not previously been shown to bind to sialylated glycans, we demonstrate that it preferentiall

142 hibited significantly reduced binding to all sialylated glycans, whereas Gal-1 bound alpha2-3- but no

143 the ionization responses for all neutral and sialylated glycans.

144 mproved desorption of both large and heavily sialylated glycans.

145 protein exhibiting no detectable binding to sialylated glycans.

146 generally not microbial cell surfaces, have sialylated glycans.

147 hat lack coding nucleic acids but do possess sialylated glycans.

148 he seal H3 bound preferentially to alpha-2,3 sialylated glycans.

149 teroids, phospholipids, phosphopeptides, and sialylated glycans.

150 MCs depends on alpha1,3-fucosylated, but not sialylated, glycans.

151 -adapted pathogen that encounters terminally sialylated glycoconjugates and free sialic acid (Sia) in

152 Sialylated glycoconjugates on the surfaces of mammalian

153 genic tetrazine, allowing for the imaging of sialylated glycoconjugates within live zebrafish embryos

154 yze the removal of sialic acid residues from sialylated glycoconjugates.

155 c) and TF-antigen, and (3) fetuin (FET), the sialylated glycoform of ASF.

156 nflammation, depends on a specific alpha-2,6-sialylated glycoform of IgG Fc to induce Interleukin 4 (

157 Gangliosides (sialylated glycolipids) play an essential role in the CN

158 Herein, we report a total of 45 sialylated glycopeptides and an increase of sialylation

159 ive proteomics strategy in which we enriched sialylated glycopeptides by SNA, labeled them at the N-t

160 Fucosylated and sialylated glycopeptides from human lactoferrin served a

161 in the presence of m-NBA the charge state of sialylated glycopeptides increased and the chromatograph

162 can quantitatively and qualitatively enrich sialylated glycopeptides more than the commercially avai

163 aracteristic fragmentation of differentially sialylated glycopeptides.

164 A sialylated glycoprotein called serum amyloid P (SAP) inh

165 processes; however, it is laborious to study sialylated glycoproteins due to the labile nature of sia

166 22 ligands, the receptor is known to bind to sialylated glycoproteins on the cell surface.

167 ral pH to label the majority of cell-surface sialylated glycoproteins while maintaining high cell via

168 Therefore, OmpA interacts with sialylated glycoproteins.

169 e to incorporate sialic acid precursors into sialylated glycoproteins.

170 We report here that sialylated glycosphingolipids with 5 N-acetyllactosamine

171 Quantitatively minor terminally sialylated glycosphingolipids with 5 to 6 LacNAc repeats

172 roles have been attributed to this family of sialylated glycosphingolipids, e.g. in modulation of ion

173 Gangliosides, sialylated glycosphingolipids, found on all vertebrate c

174 ionally modified with N-linked glycans and a sialylated glycosylphosphatidylinositol (GPI) anchor.

175 e generated their degalactosylated or highly sialylated glycovariants and compared their pathogenic e

176 n FcgammaR-independent mechanism by which Fc-sialylated glycovariants might limit proinflammatory IgG

177 retions that can result in desialylation of (sialylated) gonococcal LOS.

178 ly at amino acid 1203 (N1203R) also bound to sialylated gonococci and restored killing.

179 ctional importance of Arg-1203 by incubating sialylated gonococci with normal human serum, in the pre

180 define amino acids important for binding to sialylated gonococci.

181 ain 20 of HufH contains the binding site for sialylated gonococci.

182 are consistent with the hypothesis that the sialylated GPI anchor attached to PrP(C) acts as a synap

183 tition studies showed that pretreatment with sialylated GPIs prevented the targeting of PrP(C) to syn

184 The total neutral and sialylated HMGs were derivatized with a bifunctional flu

185 atic activity to be confined to specific non-sialylated HMOs and synergistic with a number of convent

186 in two Malawian birth cohorts revealed that sialylated HMOs are significantly less abundant in those

187 allowed the generation of SM6 decorated with sialylated human-type oligosaccharides, comparable to pl

188 heir capacity to produce inhibitory IgG4 and sialylated IgG able to mediate anti-inflammatory mechani

189 Transfer of low amounts of antigen-specific sialylated IgG Abs was sufficient to inhibit B cell acti

190 Sialylated IgG Abs, which are immunosuppressive, and Tre

191 ry from murine studies, which states that Fc-sialylated IgG alters the balance between activating and

192 ghlighting the anti-inflammatory activity of sialylated IgG antibodies.

193 Sialylated IgG Fc (sFc) increases the activation thresho

194 Sialylated IgG Fc domains have antiinflammatory properti

195 lly recombinant preparation of appropriately sialylated IgG Fc fragments.

196 nvolving basophils and the binding of highly sialylated IgG Fc to DC-SIGN-expressing myeloid cells.

197 on of IVIg, but unexpectedly, recombinant Fc-sialylated IgG or sialic acid-enriched IVIg were equally

198 Protective antibodies, including IgG4, Fc sialylated IgG, and IgA, have the capacity to modulate t

199 ment, and thus generate a fully recombinant, sialylated IgG1 Fc with greatly enhanced potency.

200 through the generation of immunosuppressive sialylated IgGs and may provide insight on the role of T

201 Here we propose that these Fc-sialylated IgGs engage a unique receptor on macrophages

202 tory mechanism mediated by anti-inflammatory sialylated IgGs that are formed on TD tolerance inductio

203 se expression and secreted immunosuppressive sialylated IgGs that were sufficient to block antigen-sp

204 that TI immune responses induced suppressive sialylated IgGs, in contrast to TD proinflammatory Th1 a

205 alizing antibodies through immunization with sialylated immune complexes.

206 able process for generating a well-qualified sialylated IVIg drug candidate with maximum Fc sialylati

207 tion, with several isomers, corresponding to sialylated lacto-N-tetraose.

208 ted during HMO fermentation and is active on sialylated lacto-N-tetraose.

209 sion of the fucosylated epitopes Lewis X and sialylated Lewis X in CHO cells, indicating competition

210 immune encephalomyelitis, Sn interacted with sialylated ligands expressed selectively on CD4(+)Foxp3(

211 e (Mphi)-restricted receptor that recognizes sialylated ligands on host cells and pathogens.

212 Sialylated lipids serve as cellular receptors for polyom

213 essing gonococcal PorB.1B in the presence of sialylated lipooligosaccharide bound more fH, more effec

214 shown to incorporate a specific glycoform of sialylated LOS within the biofilm matrix.

215 trate for the first time that in addition to sialylated LOS, the biofilm formed by NTHI in vivo conta

216 Highly sialylated LPS was ineffective in depleting bactericidal

217 ans, 3-sialyl globo unit of glycolipids, and sialylated macromolecules to 5'-CMP.

218 counterpart of factor H binding showed that sialylated meningococcal mutants that possessed gonococc

219 ce of extracellular DNA, and the presence of sialylated moieties on or between bacteria.

220 tran show that the endosomal accumulation of sialylated molecules can be largely attributed to impair

221 nfluenza infection increases sialic acid and sialylated mucin availability and enhances desialylation

222 via multiple interactions involving terminal sialylated mucin glycans.

223 sequences of trans interactions by employing sialylated multivalent antigens that can engage both CD2

224 icient and consist mostly of core 1 alpha2,6 sialylated N-acetylgalactosamine, a configuration suspec

225 nked glycans, characterized by a terminal or sialylated N-acetylgalactosamine.

226 The LC method is capable of separating sialylated N-glycan isomers differing in alpha2-3 and al

227 first total synthesis of triantennary, fully sialylated N-glycan of complex type is described.

228 ering approach led to secreted A1AT carrying sialylated N-glycan structures largely resembling its se

229 attributed to a decrease in neutral and mono-sialylated N-glycans and an increase in di-sialylated N-

230 NeuAcalpha2-6-terminated polylactosamine and sialylated N-glycans are important determinants for infl

231 eceptors for binding to HA in the absence of sialylated N-glycans at the cell surface.

232 l viruses tested interacted with one or more sialylated N-glycans but not O-glycans or glycolipid-der

233 inhibitory activities, showing a key role of sialylated N-glycans in inducing the IgM-mediated immune

234 the syntheses of bi- and triantennary fully sialylated N-glycans is described.

235 n heterogeneity was identified of the highly sialylated N-glycans of rHuEPO by extensive acetylation,

236 Sialylated N-glycans play crucial roles in physiological

237 The key step to identify the sialylated N-glycans was to quantitatively neutralize th

238 ry appeared to be affected by the absence of sialylated N-glycans, dynamin-dependent entry was not af

239 uded the detection of a new class of heavily sialylated N-glycans, including polysialylated N-glycans

240 o-sialylated N-glycans and an increase in di-sialylated N-glycans.

241 ng binding to sialylated polylactosamine and sialylated N-glycans.

242 PrP(C) has two sialylated N-linked carbohydrates.

243 Sialylated N-linked glycans have been reported to be ess

244 r knowledge, we show for the first time that sialylated N-linked glycans induce the internalization o

245 C1INH sialylated-N- and -O-glycans were not only essential for

246 Highly sialylated negatively charged glycans also exhibit high

247 linear (maltooligosaccharides) and branched (sialylated, neutral and core fucosylated biantennary IgG

248 ts and immunological responses to whole-cell sialylated NTHi were measured.

249 Using bovine fetuin (because it contains the sialylated O-glycans most commonly found on biopharmaceu

250 We find that sialylated O-glycans on these novel PILRalpha ligands, a

251 ritic cartilage and has reduced affinity for sialylated O-glycans, a glycophenotype associated with i

252 er cells, it is decorated by multiple short, sialylated O-linked glycans (MUC1-ST).

253 Sialylated oligosaccharide epitopes found on a variety o

254 alpha1-acid glycoprotein (AGP) as well as of sialylated oligosaccharide reference standards and found

255 -resolution insights into the recognition of sialylated oligosaccharides by a parasite surface protei

256 allowing the observation of both neutral and sialylated oligosaccharides in a single negative ion mod

257 dies of various complexes between TgMIC1 and sialylated oligosaccharides provide high-resolution insi

258 yses, we identified a novel interaction with sialylated oligosaccharides that resolves several prevai

259 nce standards and found that for more highly sialylated oligosaccharides the loss is greater than the

260 ifies the peptide moiety of either sulfated, sialylated, or both sialylated and sulfated glycopeptide

261 ferences in interactions with strains of the sialylated pathogen, group B Streptococcus, and with sia

262 strate that Sn plays a key role in capturing sialylated pathogens and promoting rapid proinflammatory

263 er from GDP-fucose to GlcNAc residues of the sialylated polylactosamine acceptor NeuAcalpha2-3Galbeta

264 aining NeuAcalpha2-6, with strong binding to sialylated polylactosamine and sialylated N-glycans.

265 r is similar to that reported previously for sialylated Por1B gonococci.

266 Upon incubation with human serum, Por1A and sialylated Por1B strains bound full-length human fH (Huf

267 Both sialylated PorB.1B- and (unsialylated) PorB.1A-bearing g

268 gG3 mAb are poorly galactosylated and hardly sialylated, possibly contributing to the pathogenic pote

269 red by the difficulty of generating suitable sialylated products for clinical use.

270 Airway epithelia express sialylated receptors that recognize exogenous danger sig

271 t unfavorable to bind any negatively charged sialylated receptors, consistent with the recombinant H1

272 sting that EV-D68 can use multiple redundant sialylated receptors.

273 ed homogeneous glycoforms, including a fully sialylated (S2G2F) glycoform that may gain anti-inflamma

274 atic, scalable process to produce a tetra-Fc-sialylated (s4-IVIg) IVIg drug candidate and its qualifi

275 ic eosinophilic airway inflammation and less sialylated Siglec-F ligands in their airways.

276 use of in-source and metastable decay of the sialylated species.

277 Factor H binding to the sialylated strain remained unchanged over this factor H

278 enables the controlled in vivo synthesis of sialylated structures with different interlinkages and d

279 ycans from tissues and serum have mature and sialylated structures.

280 odified with hybrid, highly fucosylated, and sialylated sugars.

281 Siglec-F recognizes sialylated sulfated glycans in glycan-binding assays, bu

282 rapid identification of various fucosylated, sialylated, sulfated glycotopes and definitive determina

283 both the sialyl Lewis-X (sLe(X)) and the di-sialylated T-antigen (NeuAcalpha2,3Galbeta1,3(NeuAcalpha

284 counts for the accommodation of the alpha2,6-sialylated terminus of a biantennary N-glycan by viscumi

285 Three mono- and di-sialylated tetra-antennary N-glycans and one mono-sialyl

286 nnary structures, as well as the increase in sialylated tetraantennary and FA3G3S[3,3,3]3 structures.

287 As a result, spleen-derived PrP(Sc) is more sialylated than brain-derived PrP(Sc).

288 on SP cells is hypoglycosylated and heavily sialylated; the characteristics of the tumor-specific fo

289 lated tetra-antennary N-glycans and one mono-sialylated tri-antennary N-glycan of rHuEPO are reported

290 eover, we observed a progressive increase of sialylated triantennary and tetraantennary structures tw

291 and 2-6 sialyllactose as well as 2-3 and 2-6 sialylated triantennary glycan.

292 The 2,6-sialylated tridecasaccharide 1 associated with the Fc fr

293 The recognition of FITC-APBA to sialylated TRITC-AF leads to the FRET signal that is ana

294 d terminal Galp residues that become readily sialylated upon addition of parasite trans-sialidases.

295 The highly sialylated vascular endothelial surface undergoes change

296 was significantly more immunogenic than the sialylated version when administered in two different ad

297 et endothelial cell adhesion molecule-1, was sialylated via alpha2,6-linkages, as shown by Sambucus n

298 ction potential waveforms and gating of less sialylated voltage-gated Na+ channels were altered consi

299 t strains when lipooligosaccharide (LOS) was sialylated, whereas PorB molecules of lptA null mutants

300 Glycans at Asn-168 were predominantly sialylated with bi- to tetra-antennary branches, and Asn