ライフサイエンスコーパス: sialylated glycan

1 Campylobacter jejuni expressing a GD1a-like, sialylated glycan.

2 teroids, phospholipids, phosphopeptides, and sialylated glycans.

3 the ionization responses for all neutral and sialylated glycans.

4 mproved desorption of both large and heavily sialylated glycans.

5 protein exhibiting no detectable binding to sialylated glycans.

6 generally not microbial cell surfaces, have sialylated glycans.

7 hat lack coding nucleic acids but do possess sialylated glycans.

8 he seal H3 bound preferentially to alpha-2,3 sialylated glycans.

9 MCs depends on alpha1,3-fucosylated, but not sialylated, glycans.

10 mutation on HA resulted in a mixed alpha2-3 sialylated glycan (alpha2-3)/alpha2-6 binding virus (NY1

11 lutinin (HA) to long (chain length) alpha2-6 sialylated glycan (alpha2-6) receptors on the human uppe

12 inding, with Gal-8N recognizing sulfated and sialylated glycans and Gal-8C recognizing blood group an

13 --enables specific binding of HA to alpha2-6 sialylated glycans and that recognition of this topology

14 re substituted with a variety of neutral and sialylated glycans and the spectra obtained were such th

15 ereas Gal-1 bound alpha2-3- but not alpha2-6-sialylated glycans, and Gal-3 bound to some glycans term

16 high-mannose glycans, fucolsylated glycans, sialylated glycans, and hybrid structures were studied.

17 sm for a parietal cell-deficient niche where sialylated glycans are expressed by a narrow band of pit

18 Sialylated glycans are found at elevated levels in many

19 Single-cell binding studies indicate that sialylated glycans are likely not required for initial a

20 Sialylated glycans are synthesized in mammals by a singl

21 glec) family that recognizes alpha2-6-linked sialylated glycans as ligands.

22 tissues and highlight a functional role for sialylated glycans as reovirus coreceptors in the CNS.

23 IL-6 secretion were enriched in ApoC-III, di-sialylated glycans at multiple A1AT glycosylation sites

24 Composed of a sialylated glycan attached to a ceramide lipid, the same

25 Two sialylated glycans bearing N-acetylneuraminic acid were

26 ot only result in accurate identification of sialylated glycans but also improve the characterization

27 O) structure, we show ABH antigens stabilize sialylated glycan clusters on erythrocyte membranes uniq

28 ows for linkage specific characterization of sialylated glycans directly from the precursor mass but

29 Hemagglutinin (HA) binds to sialylated glycans exposed on the host cell surface in t

30 irus (IBV), require specific alpha2,3-linked sialylated glycans for attachment and entry.

31 Surprisingly, Gal6S is undetectable in sialylated glycans from eosinophils and BAL fluid analyz

32 itative binding affinity of HA to alpha2-->6 sialylated glycans (human receptors) is one of the impor

33 me, fluorescence and radionuclide imaging of sialylated glycans in a murine tumor model in vivo.

34 ring 3F-NeuAc to mice dramatically decreases sialylated glycans in cells of all tissues tested, inclu

35 NAc), were incorporated into fucosylated and sialylated glycans in several cancer cell lines, allowin

36 MS analysis of sialylated glycans is challenging due to their low ioniz

37 The analysis of sialylated glycans is critical for understanding the rol

38 ies on sialic acid recognition using a novel sialylated glycan microarray containing modified sialic

39 Our results demonstrate the utility of this sialylated glycan microarray to investigate the biologic

40 icity depends on toxin binding to terminally sialylated glycans on surface glycoproteins.

41 lutinin, and Sambucus nigra agglutinin) with sialylated glycans on the same cell surface.

42 Sialylated glycans on the surface of mammalian cells act

43 Binding of sialylated glycans or other ligands triggers signals tha

44 f its B subunit, PltB, with specific lumenal sialylated glycan packaging receptors.

45 In vertebrates, sialylated glycans participate in a wide range of biolog

46 ies of the first six reported siglecs, using sialylated glycans presented in multivalent form, on syn

47 s in ionization efficiency among neutral and sialylated glycans prevent direct quantitative compariso

48 dulated by HopZ, including hopP, which binds sialylated glycans produced by GEPs in vivo.

49 in the expression of truncated core 1-based sialylated glycans rather than the core 2-based glycans

50 Crystal structures of EV-D68 in complex with sialylated glycan receptor analogues show that they bind

51 pecificity of the viral hemagglutinin to the sialylated glycan receptors (in the human host) by use o

52 on surfaces, obstructing a groove that binds sialylated glycan receptors in many other polyomaviruses

53 go-potential gastric stem cells that express sialylated glycan receptors recognized by H. pylori adhe

54 sialylated glycans) to human-like (alpha2-6 sialylated glycans) receptors is believed to be associat

55 array approach to analyze the repertoire of sialylated glycans recognized by viruses from the same c

56 ed from the aqueous phase, while neutral and sialylated glycans remained in the DCM phase.

57 Sialylated glycans serve as cell surface attachment fact

58 2)v showed a predominant binding to alpha2-6-sialylated glycans, similar to human-adapted influenza A

59 DRAG), to quantitatively compare neutral and sialylated glycans simultaneously by MALDI-MS.

60 stability and ionization bias experienced by sialylated glycan species.

61 binding to sialyl Lewis x (sLe(x)) and other sialylated glycans that decorate P selectin glycoprotein

62 which bound almost exclusively to alpha-2,6 sialylated glycans, the seal H3 bound preferentially to

63 tested preferentially utilize NeuAcalpha2-6-sialylated glycans to infect SRECs.

64 hemagglutinin (HA) from avian-like (alpha2-3 sialylated glycans) to human-like (alpha2-6 sialylated g

65 However, quantification of sialylated glycans using MS is not as reliable because o

66 tiates viral entry by engaging host receptor sialylated glycans via its receptor-binding site (RBS).

67 -R1 has not previously been shown to bind to sialylated glycans, we demonstrate that it preferentiall

68 and alkaline BGE systems, the mobilities of sialylated glycans were shifted relative to nonsialylate

69 hibited significantly reduced binding to all sialylated glycans, whereas Gal-1 bound alpha2-3- but no

70 ly, we used a nonmetabolic approach to label sialylated glycans with an independent chemistry, enabli

71 viruses, specifically bind to long alpha2-6 sialylated glycans with this topology.

72 for simultaneous profiling both neutral and sialylated glycans without derivatization or labeling.