ライフサイエンスコーパス: side

1 t side) or no significant number bias (right side).

2 vs 32.0%, P = 0.043 (1-sided), P = 0.074 (2-sided)].

3 .1% vs 8.0%, P = 0.516 (1-sided), P = 1.0 (2-sided)].

4 the middle and zinc-binding modules on each side.

5 ms hairpin intermediates on the flanking DNA side.

6 t indicate reduced attention to the affected side.

7 road sampling from inputs on the ipsilateral side.

8 which appeared to be diminished on the right side.

9 active site for SOAT2 located on the luminal side.

10 rome exhibited a bias away from the affected side.

11 uals, but instead larger around the affected side.

12 All statistical tests were 2-sided.

13 of active yaws if the lower limit of the two-sided 95% CI for the difference in rates was higher than

14 rity was shown if the upper limit of the two-sided 95% CI for the local relapse hazard ratio [HR] was

15 oup and 83.6% in the ALND group (HR, 0.85 [1-sided 95% CI, 0-1.16]; noninferiority P = .02).

16 testing for noninferiority was based on a 1-sided 97.5% confidence interval.

17 On the opposite side, a kinetoplastid-specific kinesin facilitates attac

18 microfluidic channel fabricated with double-sided adhesive tape) and all the optical components are

19 the crystal structure, such that the side-by-side aligned polyhedra are offset by 158 degrees.

20 However, the prime side also significantly modulates DENV protease binding

21 nd the superior mesenteric artery, and right-sided anastomosis.

22 information falling on the individual's left side) and allocentric neglect (neglect of the left side

23 FindNeighbour and FindNeighbour2 are server-side applications which build, maintain, and persist eit

24 isplacements under excitation from different sides, as well as one-way displacement amplification.

25 tly greater number of small pulmonary artery side branches <300 mum per cm vessel (3.8 +/- 1.1 vs. 1.

26 lial sprouting, which results in the loss of side branches and the enlargement of vessels when pericy

27 Toll signaling on the ventral side breaks the Dorsal/Cactus complex, allowing Dorsal t

28 ndom in the crystal structure, such that the side-by-side aligned polyhedra are offset by 158 degrees

29 Side-by-side comparison of PORCN and Hedgehog acyltransf

30 Side-by-side comparison of research MIOCT angiograms and

31 Surprisingly, our side-by-side comparison uncovered that the African ZIKV

32 Side-by-side comparisons confirmed massive cell death, b

33 During the memory test, subjects viewed side-by-side pictures of the previously-constructed bloc

34 distinct interactions at 4.7 A between Phe1 side chain and perfluoroaryl electrophile moiety are obs

35 A set of recently available short side chain Aquivion ionomers spanning a range of equival

36 se activation step corresponds to subsequent side chain carbonylation, likely at Lys72/73.

37 elf-assembly triples the extent of non-polar side chain contacts.

38 , producing polysulfonates with a variety of side chain functionalities in >99 % conversion within 10

39 tional transitions of a conserved tryptophan side chain in the LBD that trigger reorganization of the

40 y despite the presence of only 50% of chiral side chain in the sequence.

41 In the N139L mutant, the bulky L139 side chain inhibits timely reprotonation of E286 through

42 to enable intersheet association mediated by side chain interactions, which is characteristic of the

43 is modification is to lock the hydroxymethyl side chain of the neomycin or paromomycin ring I, as par

44 comes from kinase group and family specific side chain orientations.

45 epts a hydrogen-bonding interaction from the side chain residue of Asn315.

46 work, we studied the effect of inverting the side chain stereochemistry of individual Thr or Ile resi

47 (K side chain) with a primary amide group (Q side chain) weakens the hydrophobic interaction generate

48 ng suggests that replacing an amine group (K side chain) with a primary amide group (Q side chain) we

49 urrence revealed a positively charged lysine side chain, conserved in other flavin mediated oxidoredu

50 hain hydrogen bonding with human CRM1 Lys568 side chain, which acts as a specificity filter that prev

51 in their structure of an extended alkyl-aryl side chain, which establishes idiosyncratic interactions

52 Combined screening for m/z 130.1 along with side chain-specific J1 [M - 173](+) and J2 [M - 291](+)

53 a-carboxyl-linkages to the growing glutamate side chain.

54 a sterically hindered alpha-chiral aliphatic side chain.

55 b-states characterized by different aromatic side-chain conformations at the RNA-binding surface allo

56 ory shows that, among others, degradation of side-chain fluorinated polymers in the environment and l

57 folded conformation defined by the isoprenyl side-chain folding back over the napthoquinone in a U-sh

58 this internal redistribution and rewiring of side-chain interactions led to large cancellations resul

59 ase in rate constants with increasing carbon side-chain length.

60 all-atom statistical potential derived from side-chain packing, named OPUS-DOSP, for protein structu

61 Here, we use side-chain proton NMR relaxation dispersion measurements

62 Mutant receptors with a variety of side-chain replacements still accessed both the ON and O

63 rsions are subtle in that they do not change side-chain size, flexibility, hydropathy, charge, or pol

64 We report ncAAs with aryl carbamate side chains (PheK and FPheK) that can react with proxima

65 However, in reality, side chains are attached to the peptide backbone and sur

66 nificant variety of biologically relevant AA side chains are tolerated including those for alanine, v

67 more, it may be speculated that this pair of side chains could promote oligomerization of kalata B1 t

68 ds incorporate 13 different amine-containing side chains designed to bind in the minor groove of DNA

69 While the variation of the side chains does not alter the photoconductive propertie

70 Random oxidative modification of cryptic side chains exposed by mechanical unfolding can be slowe

71 eneric platform to target other redox-active side chains for native conjugation.

72 n supporting the importance of these charged side chains in fibril formation of betaS.

73 the peptide backbone and surrounded by other side chains in the protein scaffold in biology, which ma

74 embrane proteins fold involves the burial of side chains into lipid bilayers.

75 uences, through which a subset of the native side chains is displayed on an unnatural building block

76 In molecular dynamics simulations, the side chains of residues coordinating the zinc rearrange

77 nucleophilic functional groups, such as the side chains of serine and cysteine, using electrophilic

78 aryotic ubiquitin-like protein Pup to lysine side chains of the target protein via an isopeptide bond

79 bility and potency, whereas more hydrophilic side chains reduced VL activity.

80 time scale, specificity for protein residue side chains vs backbone as well as selectivity for diffe

81 rings (a simple model of aromatic amino acid side chains) can switch inherent dynamical tendencies fo

82 Unlike other macrolides, which carry several side chains, a single desosamine sugar is attached to th

83 gnificantly, two highly conserved asparagine side chains, each one located between two tryptophan res

84 n DeltaDeltaGsc(o) for more than half of the side chains, most of which are polar residues.

85 and electrostatic repulsions between acidic side chains, which collectively drive a sharp pH-trigger

86 ng aldoximes containing chemically different side chains, whose break-down products are involved in s

87 ic lipids with defined head groups and lipid side chains.

88 ride can specifically interact with aromatic side chains.

89 interaction generated by the six cyclohexyl side chains.

90 strong steric hindrance of bulky ethylhexyl side chains.

91 The grafting density (number of side chains/number of norbornene backbone repeats) could

92 and that a conformational switch of aromatic side-chains fine-tunes sequence specific binding affinit

93 estimate the surface exposure of amino-acid side-chains in the variable region directly from the ant

94 are possible for all the aromatic amino acid side-chains.

95 fined as receiving short- or long-term right-sided circulatory support, continuous inotropic support

96 Right-side colon cancer was also associated with gallstone dis

97 iated with pooled gastrointestinal and right-side colon cancers.

98 Side-by-side comparison of PORCN and Hedgehog acyltransferase (H

99 Side-by-side comparison of research MIOCT angiograms and clinica

100 Surprisingly, our side-by-side comparison uncovered that the African ZIKV isolate

101 Side-by-side comparisons confirmed massive cell death, before sy

102 On the organic matrix side, concerns over the polymerization stress and the po

103 versatile method, that requires only single sided contact, we measure enhanced radiative conduction

104 it preferentially interacts with the leader-side CRISPR repeat, and finally, it catalyses a nucleoph

105 pattern is observed in experiment, where the side discharges associated with honeycomb superlattice a

106 included have revealed formation dynamics of side discharges, suggesting that transverse plasma diffu

107 neuropathy (CIPN) is a common dose-limiting side effect experienced by patients receiving treatment

108 Thrombocytopenia is a major side effect of a new class of anticancer agents that tar

109 y (CIPN), the most common treatment-limiting side effect of all the most common anticancer therapies.

110 ning ventricular arrhythmias, is a potential side effect of many marketed and withdrawn medications.

111 its animal reservoirs, with the evolutionary side effect of potential persistence in incidental human

112 f thyroid iodide uptake is a well-documented side effect of the use of iodinated contrast media (ICM)

113 mal survival while demonstrating a favorable side effect profile.

114 s problem of drug resistance and the adverse side effect profiles of many TB drugs, further investiga

115 -to-moderate severity) being the most common side effect.

116 al tumors, but intestinal injury is a common side effect.

117 le therapeutic strategy to limit this common side-effect of many types of chemotherapy.

118 Without E1 and E2 enzymes, SidE effectors ubiquitylate serine residues in substrate

119 Extrapyramidal side effects (n = 7) emerged at a threshold concentratio

120 f high doses of antibiotics, which result in side effects and drug resistance.

121 treatment modality due to its remarkably low side effects and high treatment efficacy compared to con

122 ate concentrations ratio and extracted their side effects and indications as features.

123 e in blood pressure, but was devoid of major side effects and was also associated with a small reduct

124 Polyphenol metabolism and possible toxic side effects are also considered.

125 isms underpinning antipsychotic efficacy and side effects are poorly understood.

126 mportance in life sciences but light-induced side effects are serious confounding factors.

127 r replacement of Taxol(R) that mitigates the side effects associated with Cremophor EL.

128 ingle medication is unsuccessful or produces side effects at higher dosages; (3) treatment should be

129 actor, but its inhibition is associated with side effects due to its pleiotropic roles.

130 Allergic side effects during E-OIT were common but all were mild

131 in motor functions and explains some of the side effects elicited by D2R blockers when used in neuro

132 on the psychotropic medications prescribed, side effects experienced, metabolic outcomes, and scores

133 daches and nervousness have been reported as side effects following prolonged Aldara use.

134 sidered promising as an additive to minimize side effects in bleaching gel formulation.

135 ensitization can reduce the dose and adverse side effects of diverse medical treatments which require

136 nding could have therapeutic implications as side effects of Flunarizine are low and specific sepsis

137 incompatibility with existing GAL4 lines and side effects on physiology and behavior.

138 atment sessions had to be interrupted due to side effects related to the procedure.

139 ld fears relating to opioids, and experience side effects related to their use.

140 is challenging and can result in undesirable side effects such as non-specific adsorption, protein de

141 form, is associated with fewer unacceptable side effects than amphotericin, and is widely used in pl

142 current cooling strategies cause undesirable side effects that limit their clinical applications.

143 lpha checkpoint inhibitors and the potential side effects that these may have are discussed.

144 despread use is constrained by dose-limiting side effects thought to be due to activation of the pero

145 ent, but the treatment can cause significant side effects to patients.

146 lity to take tolvaptan without dose-limiting side effects was assessed, 1370 patients with ADPKD who

147 Rates of discontinuation owing to side effects were 35% for INH, 21% for RIF, and 10% for

148 Rates of discontinuation due to side effects were lower among those taking RPT/INH.

149 No short-term side effects were observed.

150 tients and discuss the possible benefits and side effects with them.

151 ally effective, they may produce undesirable side effects, and provide only partial amelioration of n

152 intervals, peripheral vasodilation, unwanted side effects, and restricted use in pediatric patients.

153 these medications are associated with severe side effects, and whether they are efficacious in treatm

154 tics are indicated because it displays fewer side effects, such as sedation and depression-like sympt

155 experiencing any of 21 common antipsychotic side effects, vital signs were obtained, fasting blood s

156 stemic ROCK inhibition causes cardiovascular side effects, we evaluated the effects of a locally acti

157 s by the antibiotics and elucidate potential side effects.

158 lve infectious inflammation without unwanted side effects.

159 ic, and does not seem to possess emetic-like side effects.

160 therapy and to minimize stimulation-induced side effects.

161 eness to dobutamine is limited with numerous side effects.

162 because of a lack of efficacy or intolerable side effects.

163 o treat cancer despite severe energy balance side effects.

164 of scopolamine, its mechanisms of action and side effects.

165 ter treatment cessation, and minimization of side effects.

166 ient's metabolism, a key condition to reduce side effects.

167 drug, enhance efficacy, and reduce unwanted side effects.

168 or designing effective treatments with fewer side effects.

169 ce in the target population with no reported side effects.

170 ilies to analyse their association with drug side effects.

171 DOR) produces similar analgesia with reduced side effects.

172 apachone treatment in humans, avoiding toxic side effects.

173 CCA growth in vivo without inducing obvious side effects.

174 -brain-barrier (BBB) and eliminates systemic side effects.

175 y to be within proteins associated with drug side effects.

176 offers further protection but has additional side effects.

177 m use of opioids is associated with multiple side effects.

178 to develop new drugs that do not cause these side-effects and have prolonged anabolic effects on bone

179 patients (15.4%) withdrew due to subjective side-effects at first dose.

180 TRUS-biopsy can cause side-effects including bleeding, pain, and infection.

181 ese remarkable advances, concerns about rare side-effects of anti-resorptive drugs, particularly bisp

182 A dye containing methyl group on the donor side exhibited blue shift in absorption and emission whe

183 Ag(0) incorporation exclusively in the prism side facets to a size regime with accelerated growth in

184 OI of the NEPTR to that in the contralateral side (FAcontra) and to that in the internal capsule (FAi

185 The two dice land on side [Formula: see text] with unknown probabilities [For

186 Here, we describe the use of side-group chemistry to control the properties of a sing

187 rdiac magnetic resonance (MR) imaging, right-sided heart catheterization, and 6-minute walk testing w

188 art remodeling differ between AF-TR and left-sided heart disease-TR.

189 flected by increased ratio of right- to left-sided heart filling pressures (0.64+/-0.17 versus 0.56+/

190 On the demand side, inaccurate forecasts and sole sourcing lead to und

191 However, more advanced right-sided lesions were detected at follow-up CT colonography

192 ent overreduction of plastoquinone and donor-side limitation of photosystem I (PSI).

193 etect a difference of 10% in accuracy by a 2-sided McNemar test.

194 Side mode suppression is electrically modulated from 6

195 'deorphanized' four more members of the Beat-Side network.

196 ia healing agents that are added to the feed side of a membrane system and seal the defect site becau

197 he unconventional myosin Dachs on the distal side of cells (nearest the center of the disc).

198 patial clustering was identified on the west side of Chicago and in the southern parts of Chicago and

199 and allocentric neglect (neglect of the left side of each object, regardless of the position of that

200 SP clusters in close proximity to the apical side of lipid droplets (LDs).

201 junctions (TJs) form a barrier on the apical side of neighboring epithelial cells in the bronchial mu

202 However, the side of origin of colon cancer (CC) still does not repre

203 locker toxin maurocalcine on the cytoplasmic side of RyR.

204 has occurred in the brain, usually the left side of space.

205 sed with elevated voltage, regardless of the side of sugar addition.

206 rmation at all locations is shifted to the 5-side of that found in mixed-sequence nucleosomes.

207 erobic bacteria were significant only on the side of the anode facing the membrane in the MPPC.

208 d them up to four conical openings on either side of the body as well as possible sensory structures.

209 gates sensory inputs from the contralateral side of the body.

210 afferent information from the contralateral side of the body.

211 s frequently with Ras activation in the back/side of the cell or with F-actin in the front of the cel

212 is exposed to luminal glucose at the apical side of the cell, suggesting that the two types of trans

213 tric modes of the acetylene groups on either side of the central atom in this system.

214 over that fibrils accumulate towards the hot side of the channel at the temperature range studied, th

215 ethanol exhibit the structures capped on one side of the channel, whereas the compounds based on [3-(

216 a, Romania, from those either grown in other side of the country or foreign samples is represented by

217 ions to bind to a quaternary epitope on each side of the dimeric capsid spike.

218 tilaginous cristae and ridges on the plantar side of the distal tibiotarsus and proximal tarsometatar

219 ually focusing cells inside a droplet to one side of the droplet using negative dielectrophoresis (nD

220 s localized in the vicinity of the abluminal side of the endothelium.

221 onocyte subset that patrols the intraluminal side of the endothelium.

222 Oleosin is synthesized on the cytosol side of the ER and extracts the LD from the ER-LD to cyt

223 e for SOAT1 that is located on the cytosolic side of the ER, while BeauIII is not accessible to the c

224 structures and was present on the cytosolic side of the ER.

225 o reciprocally monophyletic lineages on each side of the Great Rift System, high genetic exclusivity,

226 that the 2nd position towards the N-terminus side of the HA PCS (P2 position) avoided hydrophobic res

227 all alpha subunit on the intermembrane space side of the inner membrane.

228 early 100 mitochondria cluster at the apical side of the inner segment, directly below the outer segm

229 t a significant potential drop on the SrTiO3 side of the interface occurs within 2 nm of the interfa

230 tead conveys conformational changes from one side of the membrane to the other, a process we term mec

231 the substrate binding site to the alternate side of the membrane.

232 Pockets extruding from either side of the microchannels volumetrically control the num

233 ongue-driven sound sources located along the side of the mouth, and that the sonar beam direction can

234 to the mother SPB (mSPB) on the cytoplasmic side of the nuclear envelope (NE).

235 smooth hot electron distribution at the rear-side of the plastic target.

236 ve propionic acids (2 and 4) on the opposite side of the porphyrin plane.

237 (2+)-binding site located on the cytoplasmic side of the RyR channel.

238 um estimated area of 2,790 m(2) on the north side of the site's plaza and consisting of both governme

239 show that Dorsal accumulates on the ventral side of the syncytial blastoderm.

240 eal that proton binding to the extracellular side of the transporter facilitates a reorientation from

241 nergy sources for eddy generation on the two sides of Kuroshio axis.

242 yclonic) eddies are on the western (eastern) sides of Kuroshio.

243 , we added gA-free DC22:1PC vesicles to both sides of planar DC18:1PC bilayers preincubated with gA,

244 at two copies of VirD4 dimers locate on both sides of the apparatus, in between the VirB4 ATPases.

245 althcare professionals and ethicists on both sides of the debate.

246 dicate that membrane scission occurs on both sides of the midbody ring with random order and that com

247 ce to the electrochemical potentials of both sides of the QDs layer, so that electrical current causi

248 stimuli are presented simultaneously on both sides of the snout.

249 blished within mesodermal tissue on the left side only.

250 d heart failure, VT cycle length, and a left-sided-only procedure.

251 uced by a single electronic spin in a single-sided optical microcavity.

252 ion toward the small (or large) grain-filled side or an unbiased random motion.

253 bias restricted to the smaller numbers (left side) or no significant number bias (right side).

254 ard ratio [HR] 0.712, 96% CI 0.56-0.906; one-sided p value 0.0018).

255 p (hazard ratio 0.62 [95% CI 0.47-0.80]; one-sided p<0.001).

256 azard ratio [HR] 0.67, 95% CI 0.53-0.84, one-sided p=0.00030).

257 the placebo group (HR 0.76 [0.60-0.97], one-sided p=0.014).

258 rage AK clearance was 76% vs 58% on the sham side (P < .01), including 3 patients with complete clear

259 ater on the gentamicin side than the control side (P = 0.0349).

260 e control group [8.3% vs 32.0%, P = 0.043 (1-sided), P = 0.074 (2-sided)].

261 postoperatively [4.1% vs 8.0%, P = 0.516 (1-sided), P = 1.0 (2-sided)].

262 as paid to highlight possible artifacts, and side phenomena related to the absorption and relaxation

263 ing the memory test, subjects viewed side-by-side pictures of the previously-constructed block tower

264 .5]metaparacyclophane could be prepared as a side product en route to combretastatin D-2 by synchrono

265 An ionic Pd(II)Br3 dimer side product was isolated, characterized, and identified

266 -C and two C-N bonds, with water as the only side product.

267 competing boronic acids showed no crossover side-products and confirmed the stability and lack of re

268 units as well as to utilise CO2 and recycle side-products in the process are described in the third

269 arious reaction conditions, we show that the side reaction is alkyne-alkyne (i.e., Glaser) coupling.

270 rahydropyran conversion, in order to avoid a side reaction that afforded an alternative cyclization p

271 ed yield through suppression of an oxidative side reaction, while employment of a cooperative catalyt

272 eventing the possible thiolate dioxygenation side reaction.

273 the spirolactone and prevent intramolecular side reactions during chemical labeling, allowing effici

274 s of labeling reagent without intramolecular side reactions.

275 gin of competing oxidation/protodeboronation side reactions.

276 gh energy density and alleviation of cathode side reactions/corrosions, but introduces drawbacks such

277 d are prone to undergo deleterious acid-base side-reactions under the reaction conditions for homolog

278 PRP structures are dominated by four-sided right-handed beta-helices typically consisting of

279 Large right-sided serrated lesions were confirmed in 20 individuals

280 Based on these results, CC side should be acknowledged as a criterion for establish

281 ith the disulfide, not the thiol, leading to side silica coating.

282 n risk factors for infants include prone and side sleeping, soft bedding, bed sharing, inappropriate

283 d care) was 1.227 (97.5% CI 0.656-2.292; one-sided stratified log-rank p=0.77); at 24 months, the est

284 Two-sided t tests were used for comparisons between treatmen

285 The use of zwitterionic hydrogel (a double-sided tape) and commercial superglue is combined and a d

286 dy in the context of a pre-hospital or pitch-side test to detect brain injury.

287 was significantly greater on the gentamicin side than the control side (P = 0.0349).

288 ubiquitous patterning of animals whereby the side that typically faces the highest illumination is da

289 There have been arguments made by both sides that the ban will make our country safer, while ot

290 export metabolic intermediates to the apical side to nourish the outer retina.

291 uires proton transfer from the bulk at the N-side to the BNC.

292 ovel approaches, and if so, what is the flip side to the use of this technology?

293 is forward motion and a willingness on many sides to understand and address the risks and to explore

294 uximab clearly benefitted patients with left-sided tumors (vs FOLFIRI or FOLFIRI plus bevacizumab, re

295 , respectively), whereas patients with right-sided tumors derived limited benefit from standard treat

296 ns of CRYSTAL and FIRE-3, patients with left-sided tumors had a markedly better prognosis than those

297 kedly better prognosis than those with right-sided tumors.

298 On the microbial side, we found that P. palmivora encodes an active chiti

299 LUT2 is located at the basolateral, vascular side, while SGLT1 is exposed to luminal glucose at the a

300 hydroxylase (TH)-positive grafted cells per side with normalized striatal TH-immunoreactive fiber in