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1 kinetics of growth: linear, exponential and sigmoidal.
2 y than with 5-HT and its time course was not sigmoidal.
3 the oxygen binding curve becomes completely sigmoidal.
4 se and steady-state plasma concentration was sigmoidal.
8 curves for wild-type tau fibrillization were sigmoidal and correlated well with measurements of total
11 this critical scan rate, the i-v response is sigmoidal as a result of hemispherical radial diffusion.
12 stant versus phosphodonor concentration were sigmoidal, as were PhoB binding isotherms for the phosph
15 longitudinal diameter, adjusting the double sigmoidal behavior in response to changes in the time.
16 ypothesis that the mechanistic basis for the sigmoidal behavior is the same for both d-tyrosine activ
18 DNA concentrations compared to LoxP, but the sigmoidal behavior of the concentration dependence was m
24 ed five distinct stages characterized by two sigmoidal behaviors, showing the time-dependent transiti
27 toxins fail to form oligomers but still show sigmoidal binding to cholesterol-containing membranes.
28 erature dependence of steady active force is sigmoidal both in isometric and in shortening muscle.
29 4-, the velocity dependence on total Mg2+ is sigmoidal, but plateaus at high concentrations of free M
30 ents recovered by the control chimera have a sigmoidal Ca(2+) fluorescence (DeltaF/F) versus voltage
34 les and all NaCl-containing LDL samples, the sigmoidal changes in the absorbance units vs. temperatur
36 with Ca(II), Sr(II), and Ba(II) were highly sigmoidal, characterized by Hill coefficients of 2.3-6.5
39 pendence of the phosphorescence intensity is sigmoidal, consistent with cooperative actin filament bi
41 ty of the enzyme: dGTPase activity displayed sigmoidal (cooperative) behavior without DNA but hyperbo
42 reproduce the force/velocity characteristic sigmoidal correlation, while also reproducing the hand-o
43 est are sampled at a fixed time to produce a sigmoidal current-potential curve akin to a pseudo stead
44 curvature induced by endophilin and observe sigmoidal curvature/composition coupling isotherms that
49 on of the reduction potential and presents a sigmoidal curve that fits a quasireversible model and is
51 relaxation was closely fitted by a Boltzmann sigmoidal curve which allowed us to estimate the mean ME
52 vs. urine osmolality (OsmU) were fitted to a sigmoidal curve, and EC50 was determined by non-linear r
53 orded at different time scales into a unique sigmoidal curve, which clearly highlights kinetic compli
54 the HX reaction as a function of pH gives a sigmoidal curve, which reaches the maximal rate constant
55 ghted distribution of conformers describes a sigmoidal curve, with a transition midpoint near 1.5 kca
63 ffusion and transformed these data sets into sigmoidal curves characterizing the phase transition of
65 Folding was cooperative, as evidenced by the sigmoidal curves in solvent denaturation experiments.
66 peak-shaped CV and the plateau current in a sigmoidal CV, provides a simple means for calculating th
68 eets at a TOD (FTIR) of 72.4 degrees C and a sigmoidal decrease in IgY activity at TOD (ELISA) of 67.
70 d Delta21, a 50-ms depolarization produced a sigmoidal DeltaF/F versus voltage curve with a lower tha
72 ed (deuterated) water density region, with a sigmoidal density profile at the hydrophobic silane-wate
73 irion infectivity follows gp120 density as a sigmoidal dependence and reaches an apparent plateau.
74 performed under special conditions yielded a sigmoidal dependence of fiber tension on temperature--a
75 nt Kd values of 0.05 and 2.3 muM, based on a sigmoidal dependence of heme spin state on Nile Red conc
76 tration data than the Hill model, predicts a sigmoidal dependence of key parameters with calcium conc
78 By contrast, amylin fibrillogenesis has a sigmoidal dependence on heparin fragment length, with an
79 tic analysis for the double mutant reveals a sigmoidal dependence on homocysteine that is not observe
82 timuli, and steady-state depression showed a sigmoidal dependence on stimulation frequency, with half
83 e oxidation of L-ascorbate by rsAPX showed a sigmoidal dependence on substrate concentration and data
85 h respect to the filament axis had a roughly sigmoidal dependence on temperature in relaxing conditio
86 ve behavior: (i) the ATPase activity shows a sigmoidal dependence on the ATP concentration; (ii) ATPg
87 were found transported cooperatively with a sigmoidal dependence on the Cd2+ concentration (n = 1.4)
89 min produced similar results but shifted the sigmoidal dissociation curves to lower urea concentratio
90 subunit dissociation were evaluated from the sigmoidal dissociation data by assuming a single transit
91 in urea for 10 min at room temperature, the sigmoidal dissociation transitions were centered at 3.7,
92 rmers in equilibrium was used to fine tune a sigmoidal, distance-dependent dielectric function so tha
94 e, LDL colocalized with proteoglycans with a sigmoidal dose dependence (inflection point, approximate
95 limitation, we developed and implemented the Sigmoidal Dose Response Search (SDRS) algorithm, a grid
96 taCr (p < .001) and ARF (p < .001) exhibited sigmoidal dose-dependent associations to lowest hematocr
97 The ability of quantification is shown by a sigmoidal dose-response curve fitting to analyze IL-6 pr
99 say was completed in less than 3 min and the sigmoidal dose-response curve spanned an antibody concen
100 tion of RNase H by these metal ions followed sigmoidal dose-response curves suggesting cooperative me
103 the cascade without feedback showed a steep (sigmoidal) dose-response and a wide, nearly bimodal yEGF
104 so shown to target deoxyguanosine and showed sigmoidal enzyme kinetics (K0.5(deoxyguanosine) = 302 +/
108 th associated with coagulation diameter in a sigmoidal fashion (ex vivo, R(2) = 0.78; in vivo, R(2) =
109 hrough the bacterial membrane increased in a sigmoidal fashion as the AMP binding increased in time,
113 cal reaction in a ball mill exhibits unusual sigmoidal feedback kinetics that differ dramatically fro
117 the other single-loop chimeras, recovered a sigmoidal fluorescence-voltage curve indicative of skele
119 ng transient cyclic voltammogram (CV) with a sigmoidal forward wave followed by a peak-shaped reverse
120 lular calcium, maintained the characteristic sigmoidal frequency-intensity relationship and generated
121 (20 femtomoles, 1 mL) is estimated from the sigmoidal function best fitting (R(2) = 0.989) IAW exper
122 combined with data from previous studies, a sigmoidal function describes the overall trend throughou
125 (1 - e(-(t/tau))), where deltaV(L,max) was a sigmoidal function of P(aw) and tau varied with lung vol
128 lity distributions were parametrized using a sigmoidal function to determine TVFR0.5 (the temperature
131 racellular acidification response asymptotic sigmoidal functions and concentration-response behavior
133 , potentiation can be described by a pair of sigmoidal functions matched to input/output curves; (2)
136 ubstrate concentrations were best fit to the sigmoidal Hill equation, with a K(0.5) of 19.4 +/- 1.3 m
138 at although growth kinetics are likely to be sigmoidal in most cases, natural selection will restrict
139 the metal-ion dependence of DNA cleavage was sigmoidal in nature, and rates and levels of DNA cleavag
140 n curves were hyperbolic but became strongly sigmoidal in the presence of low concentrations of nucle
141 FTIR)) of 69.5 degrees C, concomitant with a sigmoidal increase in intermolecular (denatured) beta-sh
142 rownian hydrodynamics simulations, we find a sigmoidal increase of the enzymatic rate as a function o
144 by mercury poisoning, temperature-dependent sigmoidal kinetic curves, and dynamic light scattering.
145 CsgA polymerizes into an amyloid fiber in a sigmoidal kinetic fashion with a distinct lag, growth, a
147 uch nonlinear networks (NLN) readily lead to sigmoidal kinetic profiles as a function of the relative
149 aintains glucose homeostasis by displaying a sigmoidal kinetic response to increasing blood glucose l
150 s in modulation from substrate inhibition to sigmoidal kinetics (k(cat) = 1.7 +/- 0.3 s(-1), K(m) = 1
151 t if two structures are assumed to grow with sigmoidal kinetics (logistic and Gompertz) the resulting
154 rial strain alone degraded phenanthrene with sigmoidal kinetics but could not degrade alkanes or the
156 ther ACATs, EutT catalyzes the reaction with sigmoidal kinetics indicative of positive cooperativity
159 hermophilus tyrosyl-tRNA synthetase displays sigmoidal kinetics similar to those observed for activat
160 ith soluble diC8 PI(4,5)P(2) as a substrate, sigmoidal kinetics were observed, suggesting the presenc
162 Intriguingly, the inactivation exhibits sigmoidal kinetics with a Hill coefficient of 2.5 and an
163 xhibited hyperbolic kinetics, BAM2 exhibited sigmoidal kinetics with a Hill coefficient of over 3.
164 In vivo phosphorylated Cyt c shows enhanced sigmoidal kinetics with COX, and half-maximal turnover i
165 D-tyrosine, the activation reaction displays sigmoidal kinetics with respect to ATP concentration und
167 fers caffeoyl and 4-coumaroyl CoAs, exhibits sigmoidal kinetics with these substrates, and is substra
168 ow Si(OH)(4) concentrations, uptake followed sigmoidal kinetics, indicating regulation by an alloster
173 ron transport activity of CcO decreases in a sigmoidal manner during the first transition and this de
174 (a) also varied with C6PS concentration in a sigmoidal manner, whereas amidolytic activity of unlabel
175 d flow spectroscopy; the rate increased in a sigmoidal manner, with a Hill coefficient of 4, indicati
178 alpha-helicity and do not show a cooperative sigmoidal melt with temperature, indicating that these m
180 tions, a plot of Vmax versus free Co2+ shows sigmoidal metal activation of MetAP1D, both with and wit
186 ge in the substrate-velocity response from a sigmoidal one seen with the native enzyme (Hill coeffici
187 betaN changes the nitrocefin kinetics into a sigmoidal one, suggested that PAbetaN inhibited the effl
189 uation, there are important exceptions where sigmoidal or nonhyperbolic behavior is observed and have
191 e-response curve of split luciferase shows a sigmoidal pattern which indicates cooperativity in oligo
192 formation by the synthetic complex follows a sigmoidal pattern; following a quiescent induction perio
194 his equilibrium could be responsible for the sigmoidal pH dependence of the recovery of the dark-adap
196 of syn-2 in the presence of CuCl(2) showed a sigmoidal quenching curve indicating cooperative recogni
197 rm face area, a face-space coding model with sigmoidal ramp tuning provided a better account of the d
198 ucose concentrations, thereby generating the sigmoidal rate dependence that defines kinetic cooperati
200 Hb deviates from second-order kinetics, and sigmoidal reaction progress is determined by a balance b
201 reactivation of equilibrium-unfolded mAAT is sigmoidal, reactivation of the short term unfolded prote
202 rs with a time constant of 91 ms whereas the sigmoidal recovery of triggering probability lags behind
205 hmark to evidence conformist transmission: a sigmoidal relation between individuals' probability to c
207 nder ecologically plausible conditions, this sigmoidal relation can also be detected without equippin
209 40 My to identify a well-defined and clearly sigmoidal relationship between atmospheric CO(2) and sea
214 surface concentrations, however, there was a sigmoidal relationship between the initial velocity and
216 le both pERK and egr1 mRNA show a saturating sigmoidal relationship to the concentration of GnRH expo
217 addition, the probability of severing has a sigmoidal relationship to the crossover dwell time, indi
218 inst the estimated thylakoid lumen pH, and a sigmoidal relationship was obtained with a Hill coeffici
219 ty amplification for competing ligands; both sigmoidal response and affinity amplification exhibit a
220 selenide phase, as manifested by a strongly sigmoidal response in optical spectroscopy and electron
225 s biochemical characteristics, including the sigmoidal response to cholesterol, the IC(50) value towa
226 d the NBD-Cys or NBD-Hcy adducts generates a sigmoidal response with a dynamic range of 3 orders of m
227 ow-scan cyclic voltammetry (LSCV) revealed a sigmoidal response with a midpoint potential of -0.17 V
231 cromolar concentration range follow apparent sigmoidal sequential first-order kinetics, with rate con
233 c response of the bipolar cell has a similar sigmoidal shape and limiting current; however, the respo
234 t versus potential curve dependence showed a sigmoidal shape characteristic of mediated enzyme cataly
236 substrate potential features the retraceable sigmoidal shape of a quasi-steady-state voltammogram alt
237 ve P(50) values, coupled with the absence of sigmoidal shape of the O(2) equilibrium curves, was cons
240 was primarily valued according to a striking sigmoidal shape; its rate of change consistently present
241 rays are represented by two major regimes: a sigmoidal shaped i-v response for arrays acting as indiv
242 M KCl on each of the micro NEEs resulted in sigmoidal-shaped voltammograms which were reproducible a
243 vity versus concentration of coreceptors had sigmoidal shapes, implying involvement of multiple corec
245 te provides an intuitive explanation for the sigmoidal shifts in levels of phosphorylated substrate.
247 on system parameters that are necessary for sigmoidal signal-response relationships and define key p
250 eratures (or urea concentrations) and lack a sigmoidal signature characteristic of cooperative unfold
251 kinase is a monomeric enzyme that displays a sigmoidal steady-state kinetic response toward increasin
253 t initially appears as a twisted and writhed sigmoidal structure with a temperature as high as 10 MK,
254 AnsA is positively cooperative, displaying a sigmoidal substrate dependence curve with an [S](0.5) of
255 fts the reaction kinetics from hyperbolic to sigmoidal such that COX is fully or strongly inhibited u
257 ontent similar to WT and shows a cooperative sigmoidal temperature melt but with a decreased stabilit
258 ase "gated" reaction kinetics and a striking sigmoidal temperature profile that has led to a model of
259 sure of the sample (history dependence), and sigmoidal temporal behavior of the moisture-induced degr
261 s obtained with DCP-UO22+ from hyperbolic to sigmoidal, the latter characterized by Hill coefficients
262 oiled coil with the nativelike properties of sigmoidal thermal and urea-induced unfolding transitions
266 THEMATICS measures deviation from typical, sigmoidal titration behavior to identify functionally im
267 anges in the presence of urea show curved or sigmoidal titration curves suggestive of direct urea bin
268 e of the DeltaF/F versus voltage curve, from sigmoidal to bell-shaped, with a maximum at approximatel
271 8A11-Cy5 and DCP-UO22+ species changed from sigmoidal to hyperbolic at high concentrations of protei
272 follow different curve shapes, ranging from sigmoidal to hyperbolic, according to the relative impor
274 tion study of compound 12c revealed both the sigmoidal topology of the polyyn-diyl bridge and the fin
275 damage is characterized by a lag phase and a sigmoidal transition, which matches the kinetic profile
276 determined from reversible and well-defined sigmoidal transitions revealed two distinct phases refle
277 iacetyl, acetoin, and 2-butanone) followed a sigmoidal trend described by the modified Gompertz model
280 PAT to the binding of ATP was observed to be sigmoidal under fixed PhP concentrations, but substrate
281 ded as judged by CD and NMR, and all exhibit sigmoidal urea and thermally induced unfolding transitio
283 monolayer is confirmed by the appearance of sigmoidal voltammetric profile, characteristic behavior
285 ifera, both the stem and petiole had similar sigmoidal vulnerability curves but differed in pressure
286 t globular proteins exhibit a characteristic sigmoidal water adsorption isotherm at ambient condition
292 and the reciprocal absolute temperature was sigmoidal with half-maximal tension at 9.5 degrees C.
293 The ROI-biodegradability relationship was sigmoidal with higher biodegradability associated with P
294 eakly basic drug (quinine; pK(a) = 7.95) was sigmoidal with respect to -dF/M(w) values, with a profil
295 n versus reciprocal absolute temperature was sigmoidal, with a half-maximal tension at 10-12 degrees
296 ension-(reciprocal) temperature relation was sigmoidal, with a half-maximal tension at 8 degrees C.
298 dium activation of gemcitabine transport was sigmoidal, with a K0.5 of 8.5+/-0.3 mM for Na+ and a Hil
300 The pH dependence of this interaction is sigmoidal, with an apparent pK(a) for binding close to 5
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