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1  to LexA-like proteases and Escherichia coli signal peptidase I.
2 s identified as a substrate of S. pneumoniae signal peptidase I.
3 yme in the ER contains proteins unrelated to signal peptidase I.
4                    In addition, we find that signal peptidase is able to cleave after phenylalanine a
5 (SPase) can change the specificity such that signal peptidase is able to cleave pro-OmpA nuclease A i
6 d R. typhi have been demonstrated to possess signal peptidase I activity in Escherichia coli preprote
7            Finally, Gly-272 is essential for signal peptidase I activity, consistent with it being lo
8  the evidence suggests that it is cleaved by signal peptidase I and a 19-residue C-terminal domain is
9 ey P3 substrate specificity determinants for signal peptidase I and demonstrates the power of the flu
10                  All these data suggest that signal peptidase I and LexA-like proteases are closely r
11          Sequence analysis revealed that the signal peptidase I and LexA-like proteases show sequence
12 ues serine 38 and lysine 76 of S. pneumoniae signal peptidase I are critical for enzyme activity and
13 erved region, Box E, of the Escherichia coli signal peptidase I are critical for maintaining a functi
14 These data provide the first evidence that a signal peptidase is bifunctional and that SipW has a reg
15 via the novel mechanism of inhibiting type I signal peptidase, is broader than previously believed an
16  was inhibited by a C(16) compound targeting signal peptidase I, but not by a C(1) compound known to
17                              Since bacterial signal peptidase is capable of processing both prokaryot
18 imilar to LexA-like proteases, S. pneumoniae signal peptidase I catalyzes an intermolecular self-clea
19 etwork trained to identify the most probable signal peptidase I cleavage site of secreted proteins.
20 25-amino-acid leader peptide terminated by a signal peptidase I cleavage site.
21     BBA74 is posttranslationally modified by signal peptidase I cleavage to a mature 25-kDa protein.
22 xamined to date, yeast Sec11p, is related to signal peptidase I from bacteria.
23 roteases including calpain, metacaspase, and signal peptidase I have been implicated to be central me
24 proposed for the catalytic dyad mechanism of signal peptidase I in which the general base Lys-145 is
25  to incorporate full-length Escherichia coli signal peptidase I into phospholipid vesicles.
26                                    Bacterial signal peptidase I is responsible for proteolytic proces
27  we have cloned, expressed, and purified the signal peptidase I of gram-positive Streptococcus pneumo
28                       With the criteria of a signal peptidase I or II cleavage site or a predicted tr
29 e protein (Bmp), a previously characterized, signal peptidase I-processed protein.
30  amino acids that is homologous to bacterial signal peptidase I proteins.
31 s (HCV) E2-p7-NS2 precursor mediated by host signal peptidase is relatively inefficient, resulting in
32  of the consensus endoplasmic reticulum (ER) signal peptidase I site within exon 3 (UL37x3) were repl
33                                Using a novel signal peptidase I (SPase I) cleavage assay, we show tha
34 -144 and Ile-86 residues in Escherichia coli signal peptidase I (SPase) can change the specificity su
35                                              Signal peptidase I (SpI) cleavage sites were found in 46
36 tributes to the high fidelity of cleavage of signal peptidase is the Ile-144 residue.

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