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1 IFNL1, IFNL2, or Janus kinase signaling via signal transducer and activator of transcription.
2 ism of a novel mutation at the SUMO motif on signal transducer and activator of transcription 1 (STAT
3 rthermore, IFNalpha promoted the switch from signal transducer and activator of transcription 1 (Stat
4 rom patient tissues and incubated with IL28; signal transducer and activator of transcription 1 (STAT
5 dominant gain-of-function (GOF) mutation in signal transducer and activator of transcription 1 (STAT
7 activator of transcription 5b (STAT5b), and signal transducer and activator of transcription 1 (STAT
8 a T helper 1 (Th1)-type immune response and signal transducer and activator of transcription 1 (STAT
10 und more binding of the transcription factor signal transducer and activator of transcription 1 (STAT
11 ain-of-function (GOF) mutations in the human signal transducer and activator of transcription 1 (STAT
12 presses interferon gamma (IFN-gamma)-induced signal transducer and activator of transcription 1 (STAT
13 d expression of HLA-DR, NKp46, NKG2A, CD85j, signal transducer and activator of transcription 1 (STAT
14 STING leads to increased phosphorylation of signal transducer and activator of transcription 1 (STAT
15 ion of Pfn isoforms indirectly by modulating signal transducer and activator of transcription 1 (STAT
16 led-coil domain or the DNA-binding domain of signal transducer and activator of transcription 1 (STAT
17 b(+/D849V) mice and test the hypothesis that signal transducer and activator of transcription 1 (STAT
18 f hypoxia/hypoglycemia on phosphorylation of signal transducer and activator of transcription 1 (STAT
19 interferons directly upregulated tPA through signal transducer and activator of transcription 1 (STAT
20 In vivo, ruxolitinib treatment suppressed signal transducer and activator of transcription 1 activ
21 ratinocytes, IFNlambda did not phosphorylate signal transducer and activator of transcription 1 in fi
22 levels of Ifng and higher levels of phospho-signal transducer and activator of transcription 1 in th
24 reduction-oxidation-dependent mechanisms of signal transducer and activator of transcription 1 signa
28 able H. pylori decreased IFN-gamma-activated signal transducers and activators of transcription 1 and
29 or genetic activation of AMPK inhibited the signal transducer and activator of transcription-1 (STAT
30 y of stress transcription factors, including signal transducer and activator of transcription-1 (STAT
33 effect of sorafenib on SHP-1, phosphorylated signal transducer and activator of transcription 3 (p-ST
36 as recombinant SEA, stimulate activation of signal transducer and activator of transcription 3 (STAT
37 ulatory cells, accompanied by a reduction in signal transducer and activator of transcription 3 (STAT
39 e this method to demonstrate a dependence of signal transducer and activator of transcription 3 (STAT
43 Insulin-like growth factor-1 (IGF-1) and signal transducer and activator of transcription 3 (STAT
44 factor-kappaB (NF-kappaB)- and interleukin-6/signal transducer and activator of transcription 3 (STAT
45 ased IL-6 target gene expression and reduced signal transducer and activator of transcription 3 (STAT
46 ivated BMFs to produce mHGF, which activated signal transducer and activator of transcription 3 (STAT
47 Janus kinase 2 (JAK2) and phosphorylation of signal transducer and activator of transcription 3 (STAT
48 epatoprotective effects that are mediated by signal transducer and activator of transcription 3 (STAT
51 ures with autosomal dominant HIES because of signal transducer and activator of transcription 3 (STAT
54 iple pro-oncogenic pathways/genes, including signal transducer and activator of transcription 3 (STAT
56 rated previously that patients and mice with signal transducer and activator of transcription 3 (STAT
59 inhibitors reportedly involves activation of signal transducer and activator of transcription 3 (STAT
60 /2 (ERK1/2)-regulated phosphorylation of the signal transducer and activator of transcription 3 (STAT
61 nction mutations in the transcription factor signal transducer and activator of transcription 3 (STAT
62 4 and T-bet, GATA binding protein 3 (GATA3), signal transducer and activator of transcription 3 (STAT
63 lium-derived factor (PEDF) via activation of signal transducer and activator of transcription 3 (STAT
65 in-enhancer of activated B cells (NF-kappaB)/signal transducer and activator of transcription 3 (STAT
66 ion of nuclear factor kappaB (NF-kappaB) and signal transducer and activator of transcription 3 (STAT
67 ectly by raising the level of phosphorylated signal transducer and activator of transcription 3 (STAT
70 tive and interleukin 6-induced activation of signal transducer and activator of transcription 3 (STAT
72 ithout a DOCK8 mutation and 64 patients with signal transducer and activator of transcription 3 (STAT
73 ation of the oncogenic transcription factors signal transducer and activator of transcription 3 (STAT
74 kinase 2 (JAK2) and the acute phase response signal transducer and activator of transcription 3 (STAT
76 the major IL-6 downstream signaling molecule signal transducer and activator of transcription 3 (STAT
79 The activity of the transcription factor signal transducer and activator of transcription 3 (STAT
80 own genetic causes for HIES are mutations in signal transducer and activator of transcription 3 (STAT
81 g mutations in Ras GTPases and activation of signal transducer and activator of transcription 3 (STAT
84 tes keratinocytes in vitro, as manifested by signal transducer and activator of transcription 3 (STAT
85 We have revealed herein opposing roles for signal transducer and activator of transcription 3 (STAT
88 6 silencing impairs nuclear translocation of signal transducer and activator of transcription 3 (STAT
89 acellular signal-regulated kinases, SMAD and signal transducer and activator of transcription 3 (STAT
91 rosis factor (TNF), leading to activation of signal transducer and activator of transcription 3 (STAT
92 s was partially controlled by ER stress in a signal transducer and activator of transcription 3 (STAT
93 omoter to knock out the transcription factor signal transducer and activator of transcription 3 (STAT
94 report a novel finding that IL-10 triggers a signal transducer and activator of transcription 3 (STAT
95 twork centering on the transcription factor- signal transducer and activator of transcription 3 (STAT
96 its canonical role in nuclear transcription, signal transducer and activator of transcription 3 (STAT
99 in the SopB/SopE2-induced phosphorylation of signal transducer and activator of transcription 3 (STAT
100 Mechanistically, Liraglutide engages Akt and signal transducer and activator of transcription 3 (STAT
101 ally, CAMK2gamma in IECs enhanced epithelial signal transducer and activator of transcription 3 (STAT
103 tated (ATM), autosomal dominant mutations in signal transducer and activator of transcription 3 (STAT
104 Herein, we show that IL-6 robustly activates signal transducer and activator of transcription 3 (STAT
105 ore malignant phenotype via amplification of signal transducer and activator of transcription 3 (STAT
106 echanistically, ApoA-I was found to modulate signal transducer and activator of transcription 3 (STAT
107 n injury salvage kinase [RISK] pathway), and signal transducer and activator of transcription 3 (surv
109 ppressive activity of these cells depends on signal transducer and activator of transcription 3 activ
110 for chemokine release and the necessity for signal transducer and activator of transcription 3 activ
111 hepatic inflammation and fibrosis (decreased signal transducer and activator of transcription 3 activ
112 ls to produce IL-10, possibly linked to poor signal transducer and activator of transcription 3 and e
113 to EphA2 on oral epithelial cells activates signal transducer and activator of transcription 3 and m
114 utative targets for these miRNAs include the signal transducer and activator of transcription 3 and t
115 the discovery of forkhead box protein O4 and signal transducer and activator of transcription 3 as th
117 RIPC in pigs causally involves activation of signal transducer and activator of transcription 3 but n
118 l outgrowth, and pharmacologic inhibition of signal transducer and activator of transcription 3 compl
119 s time point, XBP1 bound the promoter of the signal transducer and activator of transcription 3 gene
121 used a conditional astrocytic phosphorylated signal transducer and activator of transcription 3 knock
122 , these data show that an IL-10/Janus kinase/signal transducer and activator of transcription 3 pathw
123 ng retrovirus AKT8 in rodent T-cell lymphoma/signal transducer and activator of transcription 3 pathw
125 by Gab2 deletion via regulation of Jak2 and signal transducer and activator of transcription 3 phosp
126 n effect that is accompanied by an increased signal transducer and activator of transcription 3 phosp
129 d that mutant IL-21(Leu49Pro) did not induce signal transducer and activator of transcription 3 phosp
130 Activation of S1PR2 by S1P and downstream signal transducer and activator of transcription 3 signa
131 we demonstrate that, although DL1 activates signal transducer and activator of transcription 3 signa
132 TIMP-3 in CD146(+) TSCs are regulated by JNK/signal transducer and activator of transcription 3 signa
133 y an increase in LMO4 expression mediated by signal transducer and activator of transcription 3 throu
134 embles a transcriptional complex with Stat3 (signal transducer and activator of transcription 3) and
135 MPK/sirtuin-1 inhibit the activity of STAT3 (signal transducer and activator of transcription 3) and
136 tor and the JAK1/2-STAT3 (Janus Kinase 1/2 - Signal Transducer and Activator of Transcription 3) axis
137 y discovered that high levels of host STAT3 (signal transducer and activator of transcription 3) curt
138 RFA or sham treatment with or without STAT3 (signal transducer and activator of transcription 3) inhi
139 binds Janus kinase 2 (JAK2) promoting STAT3 (signal transducer and activator of transcription 3) recr
140 hrough group 3 innate lymphoid cells, STAT3 (signal transducer and activator of transcription 3), and
141 lving upregulation of the oncoprotein STAT3 (signal transducer and activator of transcription 3).
142 administration suppressed phosphorylation of signal transducer and activator of transcription 3, a ce
143 beta, activation of the transcription factor signal transducer and activator of transcription 3, and
144 activate extracellular-regulated kinase 1/2, signal transducer and activator of transcription 3, and
145 r and activation of the transcription factor signal transducer and activator of transcription 3, and
147 uced direct cytotoxicity is mediated through signal transducer and activator of transcription 3-depen
148 n normal and ALPS T cells via a Janus kinase/signal transducer and activator of transcription 3-depen
151 mesenchymal stromal cells was consequent to signal transducer and activator of transcription 3-media
152 accharide via both nuclear factor-kappaB and signal transducer and activator of transcription 3-media
153 r and increased expression and activation of signal transducer and activator of transcription 3.
154 inase 1/2, phosphoinositide 3-kinase/AKT and signal transducer and activator of transcription 3.
155 aling 3 leads to an altered ratio of nuclear signal transducer and activator of transcription 3/NF-ka
156 mokine receptor 7 (CXCR7) expression through signal transducer and activator of transcription 3/nucle
157 duced formation of trypsin and activation of signal transducer and activator of transcription 3; thes
159 perplasia due to aberrant phosphorylation of signal transducers and activators of transcription 3 (ST
160 luble glycoprotein 130 Fc fragments, and the signal transducers and activators of transcription 3 inh
161 eased inflammation and greater activation of signal transducer and activator of transcription-3 (STAT
164 ET-1 induced Ets-like kinase-1 (Elk-1), signal transducer and activator of transcription-3 (STAT
165 es through ephrin-B1-mediated stimulation of signal transducer and activator of transcription-3 (STAT
167 Furthermore, injured RGCs display activated signal transducer and activator of transcription-3 (STAT
168 GV hinders EGFR activation and inhibits the signal transducer and activator of transcription-3 [(STA
169 d age-associated elevation in phosphorylated signal transducer and activator of transcription-3, and
170 (RTK) activity and activation of the Src/FAK/signal transducers and activators of transcription-3 (ST
171 actor of activated T cells and survivin, and signal transducers and activators of transcription-3 act
173 of transcription 6 (pSTAT6), phosphorylated signal transducers and activators of transcription 4, an
174 creased activation of hepatic growth hormone-signal transducer and activator of transcription 5 (GH-S
175 EPOR engagement of canonical Janus kinase 2/signal transducer and activator of transcription 5 (JAK2
176 nced by prolactin-induced phosphorylation of signal transducer and activator of transcription 5 (pSTA
178 actin receptor (hPRLR)-Janus kinase 2 (JAK2)-signal transducer and activator of transcription 5 (STAT
179 lly, IL2RG-JAK1-JAK3-STAT5B mutations led to signal transducer and activator of transcription 5 (STAT
180 2 (IL-2) secretion and IL-2 receptor (IL-2R)-signal transducer and activator of transcription 5 (STAT
181 ent of mice, which cooperates with activated signal transducer and activator of transcription 5 (STAT
183 dylinositol 3-kinase-Akt (PI3K-Akt) pathway, signal transducer and activator of transcription 5 (STAT
184 tant role in the non-canonical activation of signal transducer and activator of transcription 5 (STAT
185 , we found that CD69 deficiency impaired the signal transducer and activator of transcription 5 (STAT
186 Enhancement is accompanied by an increase in signal transducer and activator of transcription 5 (STAT
187 ways, one of the most notable being the JAK2/signal transducer and activator of transcription 5 (STAT
188 34(+) CP-CML cells also led to activation of signal transducer and activator of transcription 5 and t
190 The mbIL15-CAR T cells signaled through signal transducer and activator of transcription 5 to yi
191 d to poor responsiveness to IL-2 and phospho signal transducer and activator of transcription 5 up-re
192 pass grafting (CABG), only the activation of signal transducer and activator of transcription 5 was a
194 tyrosine phosphatase PTPN2 attenuates STAT5 (signal transducer and activator of transcription 5) sign
195 serves as the main signaling unit linked to signal transducer and activator of transcription 5, p38
196 educed the level of the transcription factor signal transducer and activator of transcription 5, whic
197 onstitutive activation of Janus kinase 2 and signal transducer and activator of transcription 5/3/1.
199 Here we demonstrate that the activation of signal transducers and activators of transcription 5 (ST
201 by mutations in IL-2 receptor alpha (IL2RA), signal transducer and activator of transcription 5b (STA
202 further, we crossed Kit(W-sh/W-sh) mice with signal transducer and activator of transcription 6 (i.e.
203 /-) mice had less pulmonary vascular phospho-signal transducer and activator of transcription 6 (STAT
205 for multiple transcription factors including signal transducer and activator of transcription 6 (STAT
206 f the key type 2 signal-transducing molecule signal transducer and activator of transcription 6 (STAT
207 on interleukin (IL)-4-signalling components, signal transducer and activator of transcription 6 (Stat
208 luding nuclear factor kappaB (NF-kappaB) and signal transducer and activator of transcription 6 (STAT
209 on was associated with enhanced IL-13-driven signal transducer and activator of transcription 6 activ
210 ved a reduced sensitivity to M2 polarization/signal transducer and activator of transcription 6 activ
211 decreased cytokine production and inhibited signal transducer and activator of transcription 6 phosp
212 te intracellular signaling pathways, such as signal transducer and activator of transcription 6.
215 to binding sites of pathogen-activated STAT (signal transducer and activator of transcription) and IR
216 eceptor (EGFR), which subsequently activates signal transducer and activator of transcription factor
217 cus hypersecretion by suppressing MUC5AC via signal transducer and activator of transcription factor
218 lating a novel, non-canonical and convergent signal transducer and activator of transcription factor
219 ere, we provide evidence that PTTG acts as a signal transducer and activator of transcription factor
220 ding domain mutation (p.G418_E445) in Stat4 (Signal Transducer and Activator of Transcription Factor
221 nd transcription factors (TFs) of the STAT ('signal transducer and activator of transcription') famil
222 therapy are characterized by a repressed IFN/signal transducer and activator of transcription (IFN/ST
223 activation of the JAK/STAT (Janus kinase and signal transducer and activator of transcription) intrac
224 blocking the interferon-induced Janus kinase-signal transducer and activator of transcription (JAK-ST
225 hoinositide 3-kinase (PI3K) and Janus kinase-signal transducer and activator of transcription (JAK-ST
226 growth by exploiting endogenous Janus kinase/signal transducer and activator of transcription (JAK/ST
227 required for Janus-activated tyrosine kinase/signal transducer and activator of transcription (JAK/ST
228 by the evolutionarily conserved Janus kinase-signal transducers and activators of transcription (JAK-
229 ally, IRS-1 deficiency promotes Janus kinase/signal transducers and activators of transcription (JAK/
230 L-6) secretion, which activates Janus kinase/signal transducers and activators of transcription (JAK/
231 e suggests a role for the Janus kinase (JAK)/signal transducer and activator of transcription pathway
232 0 involved the classical Janus kinase family-signal transducer and activator of transcription pathway
233 nases (JAKs) and their downstream effectors, signal transducer and activator of transcription protein
234 , inhibitor of DNA binding 3, phosphorylated signal transducer and activator of transcription (pSTAT)
235 [KRT16] mRNA expression, and phosphorylated signal transducer and activator of transcription [pSTAT]
236 reased levels of TLR4, NANOG, phosphorylated signal transducer and activator of transcription (pSTAT3
238 eir further induction through Janus kinase 2-signal transducers and activators of transcription signa
239 ivating mitogen-activated protein kinase and signal transducer and activator of transcription signali
240 ing tumor suppressors, Ras, and Janus kinase-signal transducer and activator of transcription signali
241 via JAK2 transactivation and persistent JAK-signal transducer and activator of transcription signali
242 ain-like receptor signaling and Janus kinase-signal transducer and activator of transcription signali
243 ffort to explore the effect of activation of signal transducers and activators of transcriptions (STA
244 in cytokine receptor and Janus kinase (JAK)/signal transducer and activator of transcription (STAT)
249 ior cells secrete Unpaired (Upd) to activate Signal transducer and activator of transcription (STAT)
251 R signaling, with reduced phosphorylation of signal transducer and activator of transcription (Stat)
252 f U251MG cells that harbor aberrantly active signal transducer and activator of transcription (Stat)
254 e their induction through Janus kinase (JAK)-signal transducer and activator of transcription (STAT)
255 Chronic activation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT)
256 vIL-6 activity via gp130 and gp130-activated signal transducer and activator of transcription (STAT)
257 nuclear nuclear factor kappaB (NFkappaB) and signal transducer and activator of transcription (STAT)
258 which was associated with downregulation of signal transducer and activator of transcription (STAT)
260 s cells activation of the Janus kinase (JAK)/signal transducer and activator of transcription (STAT)
261 tinct T-helper cell populations, we focus on signal transducer and activator of transcription (STAT)
262 fication of gamma-activated site (GAS)-like, signal transducer and activator of transcription (STAT)
263 unpaired-3 cytokine, which signals through a Signal transducer and activator of transcription (STAT)
264 tion is mediated by early phosphorylation of signal transducer and activator of transcription (STAT)
265 ion, IL-6 immunostaining, activation of IL-6/signal transducer and activator of transcription (STAT)
266 evidence for activation of the JAK1/JAK2 and signal transducer and activator of transcription (STAT)
267 gulation of transcription factors, including signal transducer and activator of transcription (STAT)
269 (JAK) signaling and downstream induction of signal transducer and activator of transcription (STAT)
270 eceptor alpha, which augmented and sustained signal transducer and activator of transcription (STAT)
271 development is dependent on the Janus kinase-signal transducer and activator of transcription (STAT)
272 mbined treatment, inhibition of constitutive signal transducer and activator of transcription (STAT)
273 data will show that VEGF165b inhibits VEGFR1 signal transducer and activator of transcription (STAT)-
274 ood intake, and leptin-mediated hypothalamic signal transducer and activator of transcription (STAT)-
275 h recruitment to the IL-10 promoter requires signal transducer and activator of transcription (STAT)-
277 , and functional studies using a conditional signal transducer and activator of transcription (STAT)-
278 eased expression of the transcription factor signal transducer and activator of transcription (STAT).
279 N-gamma or its downstream signaling molecule signal transducer and activator of transcription (STAT)1
280 ty and IFN-gamma production are regulated by signal transducer and activator of transcription (STAT)1
281 1, 33, and 36, inhibit constitutively active signal transducer and activator of transcription (Stat)3
282 though previous studies have shown increased signal transducer and activator of transcription (STAT)3
284 responsiveness of T cells, through affected signal transducer and activator of transcription (STAT)5
285 ect of JWH-133 on IL-17 production relied on signal transducer and activator of transcription (STAT)5
286 owledge about the significance of individual signal transducers and activators of transcription (STAT
287 Signal Transducers and Activators of Transcription (STAT
288 turn phosphorylates and activates downstream signal transducers and activators of transcription (STAT
289 n potential and activated Janus kinase (JAK)/signal transducers and activators of transcription (STAT
290 ion of nuclear factor-kappaB (NF-kappaB) and signal transducers and activators of transcription (STAT
291 g evidence points to a role for Janus kinase/signal transducers and activators of transcription (STAT
292 osophila Wnt-1) and STAT92E (sole Drosophila signal transducer and activator of transcription [STAT]
293 tic processes and hearing loss by activating signal transducer and activator of transcription (STAT1)
294 tion of a key ISG transcriptional regulator, signal transducer and activator of transcription (STAT1)
295 esulted in high levels of phosphorylation of signal transducer and activator of transcription (STAT5)
296 We also show that the signal transducer and activator of transcription (Stat92
297 JAK (Janus kinase) protein kinases to STAT (signal transducers and activators of transcription) tran
298 STAT (Signal Transducer and Activator of Transcription) transc
299 iated Jak protein tyrosine kinases and STAT (signal transducer and activator of transcription) transc
300 STAT3 is a member of STAT (signal transducer and activator of transcription) transc
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