ライフサイエンスコーパス: signal transduction mechanism

1 nal by employing an artificial transmembrane signal transduction mechanism.

2 II, appear to be integral to this nucleotide signal transduction mechanism.

3 e NMDA receptor function by an intraneuronal signal transduction mechanism.

4 the L-type Ca2+ channel is a more effective signal transduction mechanism.

5 s mutually occlusive, suggestive of a common signal transduction mechanism.

6 studies, very little is known of a possible signal transduction mechanism.

7 ic pLGIC, and opens new avenues to study the signal transduction mechanism.

8 implicates IRS-2 as a key component of this signal transduction mechanism.

9 ed protein degradation is a widely occurring signal transduction mechanism.

10 gand-induced folding could serve as an ideal signal-transduction mechanism.

11 some recent achievements in elucidating the signal transduction mechanisms.

12 ermal growth factor to co-opt the receptor's signal transduction mechanisms.

13 n mimetics and contribute to elucidating NGF signal transduction mechanisms.

14 tion between highly efficacious agonists and signal transduction mechanisms.

15 ted with or without adiponectin to elucidate signal transduction mechanisms.

16 ins which coordinate gene expression through signal transduction mechanisms.

17 which ultimately leads to proliferation via signal transduction mechanisms.

18 solution, we investigated the intramolecular signal transduction mechanisms.

19 insight into the primary mechanosensing and signal transduction mechanisms.

20 id uncoupling of A1 adenosine receptors from signal transduction mechanisms.

21 TLR9 are similar regarding localization and signal transduction mechanisms.

22 ivation, particularly through his studies on signal transduction mechanisms.

23 tor diversification and of receptor-effector signal transduction mechanisms.

24 arget binding can be coupled to a variety of signal transduction mechanisms.

25 are recognized and countered by a number of signal transduction mechanisms.

26 cells providing a new means to modulate cell signal transduction mechanisms.

27 e may have had defects in GM-CSF receptor or signal-transduction mechanisms.

28 ents a viable ligand detection mechanism, or signal transduction mechanism across membranes, distinct

29 Guidance cues and signal transduction mechanisms acting at the nerve growt

30 2)O(2) activates p90RSK to gain insight into signal transduction mechanisms activated by reactive oxy

31 Signal transduction mechanisms activated during the earl

32 TH may stem from its ability to activate two signal transduction mechanisms: adenylate cyclase and ph

33 ed for precise control over each step of the signal transduction mechanism and developing therapeutic

34 15; P = 2.63 x 10(-8)) with an intracellular signal transduction mechanism and in ACOT4 (rs35724886;

35 e used this paradigm to probe the muscarinic signal transduction mechanism and the site(s) gating noc

36 in the functional categories of defense and signal transduction mechanisms and cell cycle control, c

37 ighly essential for the research of chemical signal transduction mechanisms and for the development o

38 spite intense research, key aspects of their signal transduction mechanisms and photochemistry remain

39 s provide the tools for continued probing of signal transduction mechanisms and structural elements r

40 n sperm utilize membrane potential-dependent signal transduction mechanisms and that a depolarization

41 erstand the relationship between single-cell signal transduction mechanisms and wave propagation and

42 ern definitions of their cellular receptors' signal-transduction mechanisms and physiological and pat

43 ally regulated, which is later replaced by a signal transduction mechanism, and they demonstrate the

44 nding of endogenous receptor tyrosine kinase signal transduction mechanisms, and affect how Ang2 and

45 e area of quorum sensing: sociomicrobiology, signal transduction mechanisms, and interspecies communi

46 nterested in ;all things Wnt', including Wnt signal transduction mechanisms, and Wnt signaling in evo

47 Its ligand binding specificity and important signal transduction mechanisms are conferred by the IL-4

48 an Hh signaling, the prevailing view that Hh signal transduction mechanisms are conserved across spec

49 e normal cell migration, but that downstream signal transduction mechanisms are intact.

50 ribed and abused medications, although their signal transduction mechanisms are not well understood.

51 However, the signal transduction mechanisms are unknown.

52 re functional receptors, we have pursued the signal transduction mechanism associated with the V1a va

53 Investigation of signal transduction mechanisms associated with tensin re

54 ion of long-term potentiation (LTP), yet the signal transduction mechanisms behind the maintenance-ex

55 Results also suggest a unique signal transduction mechanism between the PXR homodimeri

56 MB has a signal transduction mechanism built within the molecule

57 The specific signal transduction mechanism by which BMP-2 regulates t

58 This provides a genomic signal transduction mechanism by which PregS could parti

59 To understand the signal transduction mechanism by which the bacterium rec

60 The results suggest cell biological and signal transduction mechanisms by which insulin modulate

61 oblasts in culture, we have investigated the signal transduction mechanisms by which phorbol esters,

62 experimental results and show that the same signal transduction mechanism can explain both short- an

63 lized to the plasma membrane and involved in signal transduction mechanisms controlling cell polarity

64 These results suggest that signal transduction mechanisms coupled to prolactin rece

65 ide a framework to study the neurobiological signal transduction mechanisms coupling neuronal electri

66 for these receptors have been cloned, their signal transduction mechanisms determined, and their int

67 stance, which involves a membrane-associated signal transduction mechanism, either at or before initi

68 Second, we investigated in detail the signal transduction mechanisms elicited by these purifie

69 In these studies, we have identified signal transduction mechanism employed by 5-HT during re

70 lly, advances have been made in defining the signal transduction mechanisms employed by these factors

71 s are highly conserved, the variations in Hh signal transduction mechanisms exhibited by existing mod

72 have revealed a new binding environment and signal transduction mechanism for heme; they have also p

73 imerization of CD44 represents an additional signal transduction mechanism for regulating receptor-li

74 lthough females appear to recruit additional signal transduction mechanisms for some analgesic drugs.

75 Our results illustrate the versatility of signal transduction mechanisms for the heme-PAS class of

76 ate starvation have been used to examine the signal-transduction mechanisms governing the Pho regulon

77 Our understanding of these signal transduction mechanisms has benefitted from studi

78 However, many Ca(2+) signal transduction mechanisms have not been explored in

79 a favourite target of investigation for new signal transduction mechanisms; however, without molecul

80 Chemosensory pathways are a major signal transduction mechanism in bacteria.

81 context, a future application of P-ETOF as a signal transduction mechanism in biosensors is outlined.

82 t multiple-step phosphorelay may be a common signal transduction mechanism in D. vulgaris.

83 Gbeta, and Ggamma subunits, are a conserved signal transduction mechanism in eukaryotes.

84 hat prion-like polymerization is a conserved signal transduction mechanism in innate immunity and inf

85 To understand the RANK-mediated signal transduction mechanism in osteoclastogenesis, we

86 phosphorelay, a variation of the predominant signal transduction mechanism in prokaryotes.

87 ligand binding and oligomerization is a key signal transduction mechanism in the AIM2 inflammasome.

88 ruitment to M(1), suggesting a role for this signal transduction mechanism in the cholinergic modulat

89 nding induces heme flattening as part of the signal transduction mechanism in the H-NOX family.

90 We focus on a light-driven signal transduction mechanism in the LOV2 domain (LOV, l

91 , the CSD proteins may be part of the stress signal transduction mechanism in the mammalian system.

92 (Ptc), in Hh reception and suggests a novel signal transduction mechanism in which Hh binds to Ptc,

93 Our study supports a signal transduction mechanism in which the helical array

94 the heart of the pharmacologically important signal transduction mechanisms in a large variety of rec

95 egulatory loci, suggesting the importance of signal transduction mechanisms in adaptation to either p

96 yclic reactions as part of the isomerization-signal transduction mechanisms in both bacteriorhodopsin

97 e findings indicate that Fgfr1 uses distinct signal transduction mechanisms in different developmenta

98 n kinase (MAPK) cascades are frequently used signal transduction mechanisms in eukaryotes.

99 ification patterns of proteins to understand signal transduction mechanisms in greater detail.

100 e mechanosensory response; the receptors and signal transduction mechanisms in olfactory neurons are

101 highly developed system for dissecting early signal transduction mechanisms in plants.

102 Investigation of the signal transduction mechanisms induced by RANTES in T ce

103 We investigated the signal transduction mechanism initiated by hypotonic cel

104 tal step forward in our understanding of the signal transduction mechanism involved in animal magneto

105 d in vivo animal models, we investigated the signal transduction mechanism involved in CB(2) receptor

106 We have investigated signal transduction mechanisms involved in alpha1, adren

107 However, signal transduction mechanisms involved in E. coli invas

108 lso be induced independently of p53, but the signal transduction mechanisms involved in regulating p2

109 these single cells permits investigation of signal transduction mechanisms involved in regulating re

110 ological synapse and suggests constraints on signal transduction mechanisms involved in T cell activa

111 lternatives, one must understand the complex signal transduction mechanisms involved in transformatio

112 regulate endothelial cell function, but the signal-transduction mechanisms involved in this process

113 IL-12 and expression of IL-10 share distinct signal transduction mechanisms involving other kinases.

114 Studies of cellular signal transduction mechanisms involving receptor-mediat

115 To better understand the signal transduction mechanisms involving small polypepti

116 However, its signal transduction mechanism is not well understood.

117 0A1-S100B protein-mediated calcium-modulated signal transduction mechanism is novel.

118 We conclude that the core signal transduction mechanism is relatively simple, with

119 li aspartate receptor, Tar, is known and its signal transduction mechanism is under investigation.

120 One of the best-described transmembrane signal transduction mechanisms is based on receptor acti

121 A better understanding of signal transduction mechanisms is of critical importance

122 sporter genes in brain neurons; however, the signal-transduction mechanism is not clearly defined.

123 acon, an oligonucleotide probe with inherent signal transduction mechanisms, is an optimal tool for v

124 membrane-bound substrates through a general signal transduction mechanism known as regulated intrame

125 , implying that autophagy is the result of a signal transduction mechanism leading from Tor to the tr

126 and not the result of interference with the signal transduction mechanism leading to calcium release

127 However, the distinct signal transduction mechanisms leading to each angiogeni

128 t is critically involved in endothelial cell signal transduction mechanisms leading to migration and

129 The signal transduction mechanism linking mitochondrial ATP

130 These results suggest that different signal transduction mechanisms may be used in neural cre

131 Thus, a signal transduction mechanism mediated by the O-(2) and

132 ood clotting, protein kinase C isoforms, and signal transduction mechanisms mediating alcohol's benef

133 und desensitization of cannabinoid-activated signal transduction mechanisms occurs after chronic Delt

134 The structure and signal transduction mechanism of Aer is providing import

135 nd the ATP-binding site are important in the signal transduction mechanism of AfGcHK.

136 ese findings distinguish a novel step in the signal transduction mechanism of agrin and raise the pos

137 d Pro41-to-Glu53 sequence is involved in the signal transduction mechanism of EnvZ.

138 in the present study was to characterize the signal transduction mechanism of phosphatidylinositol 3-

139 ucidate the role of this interaction for the signal transduction mechanism of plexins.

140 is, synaptic plasticity and cell survival; a signal transduction mechanism of sAPPs may involve modul

141 aused by ligand binding may be a part of the signal transduction mechanism of the KinB-AlgB two-compo

142 hat the role of KSR is closely linked to the signal transduction mechanism of the MAPK cascade, the p

143 for interdomain steps of the ligand-coupled signal transduction mechanism of the oxygen receptor fro

144 ine hydroxylase (TH) in the neurons, but the signal transduction mechanism of this neuromodulation is

145 dynamically how the intricate transport and signal transduction mechanisms of a model morphogen, Son

146 The signal transduction mechanisms of CD28 are not well unde

147 We suggest interference with the signal transduction mechanisms of infected macrophages a

148 Thus, the signal transduction mechanisms of neurocalcin and CD-GCA

149 results propose a role for these vesicles in signal transduction mechanisms of normal and neoplastic

150 activation is not a convergent point for the signal transduction mechanisms of NPY receptors and sigm

151 tress, but little is known of the signals or signal transduction mechanisms of plastid-to-nucleus (re

152 in development and neoplastic processes, the signal transduction mechanisms of RET remain unknown.

153 These results demonstrate that the intricate signal transduction mechanisms of supramolecular optical

154 Although the signal transduction mechanisms of the receptor tyrosine

155 ver, neither the cell biological effects nor signal transduction mechanisms of the reverse signal are

156 provides an insight into the recognition and signal transduction mechanisms of this large multifuncti

157 s study was designed to examine the role and signal transduction mechanisms of TNF alpha modulation o

158 widespread eukaryotic phosphoinositide-based signal transduction mechanisms, phosphoinositidase C-cat

159 depolarization and the subsequent Ca2+-based signal transduction mechanisms play important roles in t

160 the beta isoform of PKC in learning-related signal transduction mechanisms, potentially in the basol

161 to distinguish between the proposed PP-InsP signal transduction mechanisms: protein binding, and a c

162 of aged animals may be due to decrements in signal transduction mechanisms proximal to cAMP.

163 activation due to an upstream defect in the signal transduction mechanisms rather than in the GPIIb-

164 led to a more detailed understanding of the signal transduction mechanisms regulating digestive enzy

165 pathways to exert its effects, although the signal transduction mechanisms remain to be clarified fu

166 As and corticosteroids, although the precise signal transduction mechanisms remain to be determined.

167 This signal transduction mechanism requires attachment of typ

168 revisiae is a central component of a glucose signal transduction mechanism responsible for glucose-in

169 GCR1, GPA1, and PD1 form all of or part of a signal transduction mechanism responsible for the light-

170 rd specific cellular receptors and initiates signal transduction mechanisms responsible for inflammat

171 In an attempt to define the signal transduction mechanisms responsible for MMR-media

172 on of EF-G, suggesting that a conformational signal transduction mechanism, similar to that employed

173 The signal transduction mechanism subserving odorant recepto

174 the induction of autophagy involves a direct signal transduction mechanism that affects membrane dyna

175 esis postulates the existence of a dedicated signal transduction mechanism that induces autophagy dir

176 We studied the signal transduction mechanism that is involved in c-Jun

177 ut it is not known if it plays a part in the signal transduction mechanism that leads to the oscillat

178 This review concentrates on the signal transduction mechanism that links altered PO2 to

179 that Lemon is a component of an unusual RTK signal transduction mechanism that may involve transmemb

180 Many theories existed regarding the signal transduction mechanism that mediates this difficu

181 We propose that the absA locus encodes a signal transduction mechanism that negatively regulates

182 ggest a novel pathogen-induced transmembrane signal transduction mechanism that plays a key role in t

183 f a danger signal receptor and corresponding signal transduction mechanism that regulate pathways imp

184 nd ATF-1 phosphorylation via a PAFR-mediated signal transduction mechanism that required pertussis to

185 mechanism and is intimately involved in the signal transduction mechanism that senses and allows imm

186 CCK secretion in STC-1 cells is driven by a signal transduction mechanism that senses insoluble fatt

187 findings define a Smad-independent TGF-beta signal transduction mechanism that underlies the stimula

188 reveal those GABAergic and integrin receptor signal transduction mechanisms that are likely to be dow

189 It is therefore crucial to understand the signal transduction mechanisms that connect DNA damage w

190 d by transgenics; however, the roles of many signal transduction mechanisms that drive this different

191 ated in the genesis of cardioprotection, the signal transduction mechanisms that enable this link and

192 expression in yeast, but nitrogen-responsive signal transduction mechanisms that govern meiotic gene

193 ions, and overview a subset of the operative signal transduction mechanisms that have begun to emerge

194 e, though relatively less is known about the signal transduction mechanisms that link DNA damage in t

195 However, the signal transduction mechanisms that link glutamate recep

196 l events, and recent studies have identified signal transduction mechanisms that link glutamate-induc

197 eal SI, and that such binding is relevant to signal transduction mechanisms that mediate in vitro and

198 the mature peptide; elucidation of gastrin's signal transduction mechanisms that mediate the trophic

199 -BP by epidermal growth factor (EGF) and the signal transduction mechanisms that mediate this effect.

200 nt genes; however, little is known about the signal transduction mechanisms that modulate the express

201 in uncoupling of A1 adenosine receptors from signal transduction mechanisms that produce injury after

202 In examining the signal transduction mechanisms that regulate JunD-depend

203 mental myelination have been identified, the signal transduction mechanisms that regulate oligodendro

204 cheduled expression of genes associated with signal transduction mechanisms that regulate stomatal op

205 Microorganisms have evolved intricate signal transduction mechanisms that respond both to diox

206 ng mediators have provided insights into the signal transduction mechanisms that underlie axon growth

207 The signal transduction mechanisms that underlie the learnin

208 coupled phospholipase C (PLC) in a molecular signal-transduction mechanism that raises cytoplasmic Ca

209 The signal-transduction mechanisms that couple synaptic even

210 r, these data provide new information on the signal-transduction mechanisms that modulate the rewardi

211 receptor clustering is a recurring theme in signal transduction mechanisms, the dependence of molecu

212 Psp system: inducing signals, the underlying signal transduction mechanisms, the physiological roles

213 We emphasize on the underlying detection (or signal transduction) mechanisms, the unique roles and ad

214 cheme using fluorescence self-quenching as a signal-transduction mechanism, the fluorescence intensit

215 ay funnel into this previously unappreciated signal transduction mechanism to regulate the activity o

216 the T-type Ca2+ channel is a less effective signal transduction mechanism to the SR than is Ca2+ ent

217 ngths of light) signals act through specific signal transduction mechanisms to coordinate higher plan

218 nt wavelengths of light act through specific signal transduction mechanisms to coordinate higher plan

219 Microorganisms have adapted intricate signal transduction mechanisms to coordinate tolerance t

220 iatum there is a switch in receptor-mediated signal transduction mechanisms to produce a supersensiti

221 G Proteins provide signal transduction mechanisms to seven transmembrane re

222 we achieved by specifically considering the signal transduction mechanism ultimately resulted in fac

223 The signal transduction mechanism underlying PDGF-induced ch

224 Studies of the signal transduction mechanisms underlying learning and m

225 r, these data provide new information on the signal transduction mechanisms underlying opiate actions

226 To understand the signal transduction mechanisms underlying the activation

227 To investigate the signal transduction mechanisms used by dopamine in devel

228 ated receiver domain, show that NtrC1 uses a signal transduction mechanism very similar to that of Dc

229 This signal transduction mechanism was analysed by creating m

230 The signal transduction mechanism was elucidated by undertak

231 he importance of cholesterol to a variety of signal transduction mechanisms, we assessed the effect o

232 To gain insight into cold signal transduction mechanisms, we isolated Arabidopsis

233 uction of nitrite to NO., and the subsequent signal transduction mechanisms were all significantly im

234 These results define in GPCRs a canonical signal transduction mechanism where ligand binding induc

235 far in the quantitative understanding of the signal transduction mechanisms where NO is involved.

236 n in L. brevis operates via a multicomponent signal transduction mechanism wherein the presence of gl

237 iological state of the cell is controlled by signal transduction mechanisms which regulate the balanc

238 lts are confirmation of a hallmark of the HK signal transduction mechanism with atomic resolution on

239 entified, hindering our understanding of the signal transduction mechanism within the complex.

240 a foundation for further characterization of signal transduction mechanisms within CetA/CetB.

241 or protein in the nucleus suggests there are signal transduction mechanisms within the nucleus that r