ライフサイエンスコーパス: signal transduction pathway

1 used these genes to investigate the c-di-GMP signal transduction pathway.

2 including those involved in the phytochrome signal transduction pathway.

3 a role in cell proliferation through the Shh signal transduction pathway.

4 ated kinase/mitogen-activated protein kinase signal transduction pathway.

5 /extracellular signal-regulated kinase (ERK) signal transduction pathway.

6 nd IL-1 receptor-like 1 (IL1RL1), act in one signal transduction pathway.

7 bly through a hitherto unknown communication signal transduction pathway.

8 w that it is an indispensable part of the OS signal transduction pathway.

9 proteins and the mechanisms that govern this signal transduction pathway.

10 the immunoreceptor tyrosine-based activation signal transduction pathway.

11 ed to inflammation or activation of the STAT signal transduction pathway.

12 rganelles harboring components of the visual signal transduction pathway.

13 ion, suggesting early activation of the STAT signal transduction pathway.

14 receptor conformations activating different signal transduction pathways.

15 in degradation, subcellular localization and signal transduction pathways.

16 ral nervous system functions through diverse signal transduction pathways.

17 r stromule frequency in reaction to internal signal transduction pathways.

18 ase-3 (Gsk-3) is a key regulator of multiple signal transduction pathways.

19 aches to cancer treatment focus on targeting signal transduction pathways.

20 is, and cellular regulation of immune system signal transduction pathways.

21 one of the critical steps for many cellular signal transduction pathways.

22 cellular outputs and responses by modulating signal transduction pathways.

23 ncert exert reversible control over numerous signal transduction pathways.

24 cytokinesis 8 (DOCK8), which are involved in signal transduction pathways.

25 process, and is often activated by multiple signal transduction pathways.

26 factors act indirectly via receptor-mediated signal transduction pathways.

27 thyroid carcinoma and describe the involved signal transduction pathways.

28 ARPs are not simply downstream executors of signal transduction pathways.

29 /ligand interactions that stimulate numerous signal transduction pathways.

30 esolution that is necessary in understanding signal transduction pathways.

31 rocesses as a mediator of cross-talk between signal transduction pathways.

32 required to selectively modulate downstream signal transduction pathways.

33 ity and trafficking, and the organization of signal transduction pathways.

34 ght allow activation of yet to be identified signal transduction pathways.

35 lation of cytokine receptors or TLR-mediated signal transduction pathways.

36 peutically important phosphatases feature in signal transduction pathways.

37 and enzymatic complexes to the regulation of signal transduction pathways.

38 nical stimuli and initiate specific cellular signal transduction pathways.

39 unraveling the general principles underlying signal transduction pathways.

40 sis of cell-surface proteins and controlling signal transduction pathways.

41 l signals to the activation of intracellular signal transduction pathways.

42 cluded cytokine production and activation of signal transduction pathways.

43 ed the effects of 4-OH-E2 on redox-sensitive signal transduction pathways.

44 ular signal-regulated protein kinases (ERKs) signal transduction pathways.

45 terial chemotaxis is one of the best studied signal transduction pathways.

46 response require a coordinated regulation of signal transduction pathways.

47 ity involves a complex interplay between key signal transduction pathways.

48 cytes involving TLR4/MyD88 and NFkappaB/MAPK signal transduction pathways.

49 e strict specificity of phototropin-mediated signal transduction pathways.

50 cal macrophages is likely mediated via STAT1 signal transduction pathways.

51 d that Epr3 is integrated into the symbiosis signal transduction pathways.

52 ted proteins into complexes, organelles, and signal transduction pathways.

53 arcinoma cells and for the study of involved signal transduction pathways.

54 duced cell transformation and the associated signal transduction pathways.

55 lotting were used to determine activation of signal transduction pathways.

56 for sensory physiology and modulate various signal transduction pathways.

57 Cells communicate with their environment via signal transduction pathways.

58 bosome biogenesis, and phosphorylation-based signal transduction pathways.

59 lular messenger that plays a central role in signal transduction pathways.

60 s are evolutionarily conserved regulators of signal transduction pathways.

61 the measured responses of a few proteins or signal transduction pathways.

62 opmental decision-making in association with signal-transduction pathways.

63 pressor genes, and dysregulation of multiple signal-transduction pathways.

64 9 transcription is mediated through cAMP/PKA signaling transduction pathway.

65 e a role in regulating protein stability and signaling transduction pathways.

66 elease into the cytosol is a hallmark of key signalling transduction pathways.

67 a can function as an integrated two-receptor signal transduction pathway, a finding with implications

68 Signal transduction pathways activated by chemoattractan

69 MK2 is also one of the major players in the signal transduction pathways activated in response to DN

70 enic responses depending upon the balance of signal transduction pathways activated, targeting specif

71 and molecular composition, the intracellular signal transduction pathways, active during specific pha

72 trosylation can be an important modulator of signal transduction pathways, akin to phosphorylation.

73 w-abundance signaling molecules that control signal transduction pathways and are necessary for cellu

74 anslational modification controlling several signal transduction pathways and displaying an acute eff

75 tein FHL2 is a crucial modulator of multiple signal transduction pathways and functions as a scaffold

76 to CXCL16 stimulation, but exhibited unique signal transduction pathways and homing properties.

77 ting actin cytoskeletal dynamics, regulating signal transduction pathways and inhibiting host secreto

78 Ras GTPase mediates several cellular signal transduction pathways and is found mutated in a l

79 albumin concentrations, which disrupt normal signal transduction pathways and lead to an overactivati

80 ls of their host genes involved in olfactory signal transduction pathways and other critical neurolog

81 G-protein-coupled receptors regulate signal transduction pathways and play diverse and pivota

82 ulated kinase 1/2, and ribosomal S6 kinase 1 signal transduction pathways and subsequent increase in

83 t the role of the ERM proteins in regulating signal transduction pathways and suggests that modulatio

84 nderstood with our evolved knowledge of many signal transduction pathways and the way they converge a

85 rk architecture to integrate the activity of signal transduction pathways and transcriptional regulat

86 comprised different, functionally unrelated signal transduction pathways and were expressed in diffe

87 (5)beta(1) integrin, identify the downstream signal transduction pathway, and further investigate the

88 3/phosphoinositide 3-kinase/protein kinase B signal transduction pathway, and that can be overcome by

89 and cell cycle control, microRNA silencing, signal transduction pathways, and hormone-driven disease

90 bolism are tightly controlled by enzymes and signal transduction pathways, and their dysregulation le

91 veal a cross-talk among the external milieu, signal transduction pathways, and transcription factors

92 Systems biology approaches to defining how signal transduction pathways are integrated at the level

93 Host cell signal transduction pathways are often targets of bacter

94 rticipates in the canonical Wnt/beta-catenin signal transduction pathway as well as modulating cytosk

95 Increasing knowledge about signal transduction pathways as drivers of cancer growth

96 ment, generating a holistic view of cellular signal transduction pathways as exemplified by analysis

97 tanding the feedback regulation of olfactory signal transduction pathways as well as the control of s

98 this study are the first to define the LytSR signal transduction pathway, as well as determine the me

99 is the ligand-specific activation of certain signal transduction pathways at a receptor that can sign

100 oral manner and therefore fills a gap in the signal transduction pathway between pathogen recognition

101 ling, via FGF receptor 4 (Fgfr4), mediates a signal-transduction pathway between Wnt16 and Dlc, but n

102 ches to tune the activation of intracellular signal transduction pathways both predictably and select

103 llular localization is dependent not only on signal transduction pathways, but also on mechanical str

104 ein methylation is an important modulator of signal transduction pathways, but methyltransferases the

105 nal cues are controlled by a small number of signal-transduction pathways, but how the specificity of

106 d to show binding and activation of Dectin-1 signal transduction pathway by the beta-glucan-containin

107 P450 expressed only in males, as well as the signal transduction pathway by which episodic GH solely

108 receptors, and some family members modulate signal transduction pathways by acting as co-receptors.

109 eins play pivotal roles in the regulation of signal transduction pathways by connecting upstream rece

110 The activation of cellular signal transduction pathways by solar ultraviolet (SUV)

111 diated, in part, through redox-sensitive AKT signal transduction pathways by up-regulating the expres

112 However, the signal transduction pathways by which extracellular sign

113 In budding yeast, one such signal transduction pathway called the mitotic exit netw

114 Changes in these signal transduction pathways can lead to differential ge

115 biotic stresses are often very specific, but signal transduction pathways can partially or completely

116 lles and membrane-trafficking intermediates, signal transduction pathways, cell cycle regulators, the

117 tion of mtDNA may emerge from studies of how signal transduction pathways command mitochondrial funct

118 of which is controlled through a proteolytic signal transduction pathway comprising a sensor protein

119 re we characterise a multi-step phosphorelay signal transduction pathway consisting of TcsA, TcrA, Fs

120 tors of the phosphoinositide 3-kinase (PI3K) signal transduction pathway contribute to the hypothalam

121 Multiple wound-related signal transduction pathways control the deposition of E

122 tical cellular stress response; however, the signal transduction pathways controlling autophagy induc

123 Ras is at the hub of signal transduction pathways controlling cell proliferat

124 Signal transduction pathways converge upon sequence-spec

125 ed, indicating that targeting a specific D2R signal transduction pathway could allow for more precise

126 ession profiles of genes enriched in several signal transduction pathways critical for coronary heart

127 links to and regulates synaptic adhesion and signal transduction pathways critical for normal cogniti

128 However, the signal transduction pathways culminating in the biologic

129 r regulation of several processes, including signal transduction pathways, development, and disease.

130 Suppressing FGFR or its downstream signal transduction pathways diminished Lgr5-expressing

131 ese results suggest that CnrN functions in a signal transduction pathway downstream of AprA and CfaD

132 s, cytoskeletal protein networks and complex signal transduction pathways driven by localized protein

133 ignaling pathway is considered to be a major signal transduction pathway during embryonic development

134 dissect in vivo the requirement of different signal transduction pathways emanating from KIT for tumo

135 Activation of the EphR-Ephrin signal transduction pathway enhances S863 phosphorylatio

136 lso function as modulators of a multitude of signal transduction pathways evoked by environmental sti

137 has been proposed to play a central role in signal transduction pathways evoked by the drought and s

138 on the PhoB and TctD mediated two-component signal transduction pathways exemplify how P. aeruginosa

139 ects through direct interactions with ILK, a signal transduction pathway firmly linked to cell motili

140 The signal transduction pathways for the cross talk between

141 NPM-ALK co-opts several intracellular signal transduction pathways, foremost being the STAT3 p

142 Notch signaling is a ubiquitous signal transduction pathway found in most if not all met

143 thesis with sphingolipid metabolism and link signal transduction pathways from the plasma membrane to

144 The evolutionary conserved Wnt signal transduction pathway has long been known for its

145 Although central elements in the cytokinin signal transduction pathway have been identified, mechan

146 Light signal transduction pathways have been extensively studi

147 olecular mechanisms that underlie plant cell signal transduction pathways have successfully used the

148 entified crucial pathways, including several signal transduction pathways, hormone response, oxidativ

149 lly disordered proteins are instrumental for signal-transduction pathways; however, many mechanistic

150 The inference is that engaging a particular signal transduction pathway in a defined cell type leads

151 rovides evidence for a novel target gene and signal transduction pathway in adipocytes and indicates

152 lem of signaling regulation, a two-component signal transduction pathway in bacterial homeostasis, an

153 r microenvironment, activating the NF-kappaB signal transduction pathway in MDSCs and regulating thei

154 Our data describe a novel signal transduction pathway in neurons whereby ApoE acti

155 arious BMP receptors and members of the SMAD signal transduction pathway in nociceptive sensitization

156 e Arabidopsis thaliana forward nuclear auxin signal transduction pathway in Saccharomyces cerevisiae

157 CIATED RECEPTOR KINASE1 (BAK1) to initiate a signal transduction pathway in which autophosphorylation

158 n the bacterial phosphotransferase system, a signal transduction pathway in which phosphoryl transfer

159 enes were involved in multiple signaling and signal transduction pathways in a wide variety of cellul

160 mor microenvironment, epithelial plasticity, signal transduction pathways in cancer progression, and

161 Protein kinases regulate the majority of signal transduction pathways in cells and have become im

162 The crosstalk between these signal transduction pathways in coordinating environment

163 Epigenetic enzymes modulate signal transduction pathways in different biological con

164 mprehensive, validated, and annotated map of signal transduction pathways in inflammatory Mvarphis ba

165 Calcium is a second messenger in signal transduction pathways in plants, and it has been

166 Crk and CrkL are capable of initiating major signal transduction pathways in response to extracellula

167 w for a screening-type analysis of potential signal transduction pathways in the cells.

168 een used as tools for selectively modulating signal transduction pathways in vitro and in vivo.

169 3 receptors via both PKC/Ca(2+) and PKA/cAMP signal-transduction pathways in vitro.

170 tion as molecular switches within elementary signal transduction pathways, including the regulation o

171 catenins and regulates several intracellular signal transduction pathways, including Wnt/beta-catenin

172 Emerging work points to Nrf2-Keap1 signal transduction pathway inhibitors, including Bach1

173 lix transcription factors and inhibited by a signal transduction pathway initiated by TOO MANY MOUTHS

174 imeric G proteins play a pivotal role in the signal-transduction pathways initiated by G-protein-coup

175 lists confirms the pan-cancer importance of signal transduction pathways, innate and adaptive immune

176 These results indicate that a signal transduction pathway involved in self-renewal and

177 However, little is known about the signal transduction pathways involved in mechanical stim

178 However, signal transduction pathways involved remain largely uni

179 Traditional study of signal transduction pathways involves mapping cellular s

180 These data define a novel signal transduction pathway involving c-src that is acti

181 trations is reported that operates through a signal transduction pathway involving multivalent intera

182 Our studies have identified a signal transduction pathway involving ROS, PKC, ERK, and

183 vascular remodeling is mediated by specific signal transduction pathways involving NFAT or C/EBPbeta

184 FLS is controlled by multiple interconnected signal transduction pathways involving reversible phosph

185 activation is not mediated by the canonical signal transduction pathway, involving ApoER2/VLDLR and

186 BR signal transduction pathway is well elucidated in Arabid

187 fectiveness of cancer therapeutics targeting signal transduction pathways is comprised of a diversity

188 ferentially signal through a small number of signal transduction pathways is not well resolved.

189 ent analysis reveals that the 'plant hormone signal transduction' pathway is enhanced during pollen-p

190 highly homologous yet distinct components of signal transduction pathways known to regulate cell surv

191 PKR also mediates activation of signal transduction pathways leading to interferon beta

192 odulate a number of key elements in cellular signal transduction pathways linked to apoptosis, angiog

193 Understanding the mechanism of the signal transduction pathways mediated by these proteins

194 rstanding of the cellular mechanisms and the signal transduction pathways mediating host-virus intera

195 First, we examined whether Pfs47 affected signal transduction pathways mediating mosquito immune r

196 To address the signal transduction pathways mis-regulated in renal inju

197 lls are endowed with a PLCbeta2/IP3 R3/TRPC6 signal transduction pathway modulating release of neurop

198 actions between HIV-1 proteins and key human signal transduction pathways necessary for activation of

199 evealed as the upstream components of growth signal transduction pathway of psoriatic pathogenesis.

200 The signal transduction pathway of the DNA damage response (

201 nd assessed systemic insulin sensitivity and signal transduction pathways of glucose utilization at t

202 lization of IL-21 contributes to the overall signal transduction pathways of the Ag receptor to influ

203 at design principles inspired by the complex signal-transduction pathways of eukaryotes may be genera

204 However, the underlying intracellular signalling transduction pathways of alpha-syn-mediated m

205 Thus, two signal transduction pathways, one depending on PI3K, ano

206 levels) via either its native two-component signal transduction pathways or synthetic signalling sen

207 somatic events converging on the same gene, signal transduction pathway, or protein complex in diffe

208 The signal transduction pathways, orchestrating the differen

209 suppressed following stimulation by multiple signal transduction pathways, our findings also suggest

210 view Ca2+/CaM as a limiting resource in the signal transduction pathway owing to its low abundance r

211 a transcription factor of the abscisic acid signal transduction pathway, plays a major role during s

212 The signal transduction pathways present during the early ph

213 stalk mechanisms on the dynamics of parallel signal transduction pathways; reciprocal side-effects be

214 structure, constitutive activity, isoforms, signal transduction pathways, regional differences in ex

215 Signal-transduction pathways regulated by extracellular

216 mic reticulum stress and modulating multiple signal transduction pathways regulating cancer cell grow

217 To screen for signal transduction pathways regulating mRNA export comp

218 ar mechanisms that negatively regulate these signal transduction pathways remain poorly understood.

219 In this study, we investigated the signal transduction pathways responsible for APOBEC3B up

220 We therefore investigated the signals and signal transduction pathways resulting in ACSL1 inductio

221 Little is known about the signal transduction pathway(s) controlling PhyR phosphor

222 Investigating the YopH-targeted signal transduction pathway(s) in neutrophils during inf

223 Yet, the signal transduction pathway(s) seems to be noncanonical,

224 This highlights the existence of signal transduction pathway(s) that limit plant developm

225 rs of sub-zero acclimation, although the CBF signal transduction pathway seems to be less important d

226 eration, and survival; activation of the key signal transduction pathways STAT3 and mTORC1; and expre

227 nscription 3 (STAT3), while preserving other signal transduction pathways such as Akt and extracellul

228 ns that constitutively activate the JAK-STAT signal transduction pathway, such as JAK2 V617F, or exon

229 or internalization and activation of several signal transduction pathways, such as phosphoinositide 3

230 ogy (GO) terms associated with signaling and signal transduction pathways, suggesting the presence of

231 We also found signal transduction pathways tend to show extensive dyna

232 h factor (HGF)/c-Met supports a pleiotrophic signal transduction pathway that controls stem cell home

233 gonadotropes, we investigated the potential signal transduction pathway that conveys the inhibitory

234 The unfolded protein response (UPR) is a signal transduction pathway that coordinates cellular ad

235 cterial phosphotransferase system (PTS) is a signal transduction pathway that couples phosphoryl tran

236 the MAP kinase signaling cascade, a central signal transduction pathway that governs a broad spectru

237 minin acts both like a component of the FGF4 signal transduction pathway that governs trophoblast pro

238 The major pathway is the canonical ethylene signal transduction pathway that incorporates CONSTITUTI

239 tch signaling is an evolutionarily conserved signal transduction pathway that is essential for metazo

240 ctivity of the alpha7 nAChR is mediated by a signal transduction pathway that is independent of ion c

241 ieA is part of an operon encoding the VieSAB signal transduction pathway that is nearly silent in V.

242 omeostatic synaptic plasticity; however, the signal transduction pathway that links reduced Ca(2+)-le

243 st that H2O2 signaling is under control of a signal transduction pathway that links the respiratory c

244 /4/5/8 operate downstream of cytokinins in a signal transduction pathway that negatively regulates pl

245 servations suggest that metformin inhibits a signal transduction pathway that results in an inflammat

246 n of RNA-binding proteins is integrated with signal transduction pathways that also govern gene trans

247 eting agent that invokes the blockage of two signal transduction pathways that are central to the dev

248 fully capable of activating several cellular signal transduction pathways that are ICP27 dependent.

249 r signaling, which may begin to identify the signal transduction pathways that are important in the p

250 om cytotoxin-induced death by stimulation of signal transduction pathways that are linked to prion pr

251 vival are poorly understood, but may include signal transduction pathways that are modulated by chang

252 Signal transduction pathways that are regulated by pH an

253 we can elucidate and dissect the fundamental signal transduction pathways that control cell behavior

254 Thus, amino acids could activate signal transduction pathways that control cell metabolis

255 the augmented IHVR, is regulated by multiple signal transduction pathways that could be potential the

256 r recovery from pneumonia, and modulation of signal transduction pathways that have been linked to pr

257 VEGF-A stimulates signal transduction pathways that modulate endothelial o

258 er, after decades of basic research into the signal transduction pathways that promote cancer cell su

259 Restraint of intracellular signal transduction pathways that promote release of mas

260 The signal transduction pathways that promote this rapid pro

261 cently identified as a key components in the signal transduction pathways that regulate activation of

262 tor phosphorylation, which in turn activates signal transduction pathways that regulate cell-collagen

263 Relatively little is known regarding key signal transduction pathways that serve as cytosolic bri

264 Many of the signal transduction pathways that trigger activation of

265 ional modification (PTM) is a key feature of signal-transduction pathways that allows the modulation

266 ment of cancer is to understand the cellular signaling transduction pathways that cause cancer at the

267 h contribute to TAV by initiating outside-in signaling transduction pathways that elicit monocyte rec

268 ct as an extension of the established immune signal transduction pathways, thereby adding an extra la

269 However, the signal transduction pathways through which mGluR5s regul

270 of the CWI mitogen-activated protein kinase signal transduction pathway to target the relocalization

271 led receptors (GPCRs) utilize (at least) two signal transduction pathways to elicit cellular response

272 ossibility is that information is encoded in signal transduction pathways to ensure stimulus- and cel

273 lusters, ranging from epigenetic control and signal transduction pathways to global and specific tran

274 that acts as a docking platform integrating signal transduction pathways to nucleic acid-related pro

275 ng CPEB4, thereby integrating phase-specific signal transduction pathways to regulate cell cycle prog

276 Bacteria frequently use two-component signal transduction pathways to sense and respond to env

277 rahepatocytic beta1 integrins, which trigger signal transduction pathways toward choleresis.

278 n, suggesting that a nonclassical EGFR-based signal transduction pathway triggered ERK2-NF-kappaB act

279 variety of proteins to fulfill key roles in signal transduction pathways triggered by activation of

280 conclude that mDia1 integrates oxidative and signal transduction pathways triggered, at least in part

281 d its metabolite sphingosine 1-phosphate, on signal transduction pathways under cell stress is import

282 diated by toll-like receptor 4 (TLR-4)/MyD88 signal-transduction pathway up-regulation of MLCK expres

283 nal permeability was mediated by TLR-4/MyD88 signal-transduction pathway up-regulation of MLCK.

284 This mechanism might be a general signal transduction pathway used by PP2A to initiate cel

285 e Hedgehog pathway is one of the most common signal transduction pathways used by mammalian cells.

286 S1P1 directly activated the Jak-STAT3 signal-transduction pathway via IL-6.

287 Our results indicated that the p38-related signal transduction pathway was dramatically affected by

288 ty of the nuclear factor (NF)-kappaB and p53 signal transduction pathways was monitored using the rep

289 Signal transduction pathways were characterized in Ba/F3

290 oreover, loci expressing other regulators of signal transduction pathways were conspicuous among the

291 Targeting signal transduction pathways which promote therapy resis

292 is transduced by a receptor kinase-mediated signal transduction pathway, which is distinct from anim

293 hat often lead to dysregulation of oncogenic signal transduction pathways, which in turn alters downs

294 ors of NFkappaB and MAPKs were used to study signal transduction pathways while TLR4 and MyD88 were s

295 dings illuminate an evolutionarily conserved signal transduction pathway with essential roles in meta

296 RNPK), a protein known to integrate multiple signal transduction pathways with gene expression, as a

297 to drought stress depend on highly regulated signal transduction pathways with multiple interactions.

298 rategy for treating the disease by modifying signal transduction pathways with small-molecule drugs.

299 gnals on the exterior of a cell and activate signal transduction pathways within the cell.

300 ls from central energy/stress sensing kinase signal transduction pathways within the nucleus.