ライフサイエンスコーパス: signaling cascade

1 aluronan synthase HAS2 by activating the Akt signaling cascade.

2 nt growth, driven instead by a FGFR/MAPK/ID1 signaling cascade.

3 ity-dependent, non-apoptotic Bax/Bak-caspase signaling cascade.

4 extracellular signal-regulated kinase [ERK]) signaling cascade.

5 ally upstream of the mitochondrial apoptosis signaling cascade.

6 phospholipase (PLC)/ protein kinase C (PKC) signaling cascade.

7 position in the activating receptor-mediated signaling cascade.

8 roperties of Kv4 channels through a specific signaling cascade.

9 mbrane fraction, where it activates the cAMP-signaling cascade.

10 edgehog (HH) paracrine system as a candidate signaling cascade.

11 ds to TLR2 degradation and disruption of the signaling cascade.

12 ine kinase/phosphatidylinositol 3-kinase/Akt signaling cascade.

13 ple signalling sub-pathways involved in this signaling cascade.

14 lutionarily conserved peroxiredoxin-p38/MAPK signaling cascade.

15 orylates multiple proteins in the checkpoint signaling cascade.

16 ght-controlled activation of the Raf/MEK/ERK signaling cascade.

17 ase 1-independent manner to activate the WNT signaling cascade.

18 tivation and pMad phosphorylation within the signaling cascade.

19 at and cocaine on the proliferative TGF-beta signaling cascade.

20 a negative feedback mechanism in the Ain/Lux signaling cascade.

21 y constraints on the modules involved in the signaling cascade.

22 (+)-induced stimulation of the ASK1-mediated signaling cascade.

23 ma-metalloproteinase/EGFR-dependent MAPK/ERK signaling cascades.

24 ore distant cells, where they induce various signaling cascades.

25 ucrose non-fermentative-related kinase-based signaling cascades.

26 iple binding partners and integrates diverse signaling cascades.

27 tes the canonical and noncanonical NF-kappaB signaling cascades.

28 hate oxidases (NOX) control various cellular signaling cascades.

29 ost response by targeting key proteins along signaling cascades.

30 (NLR), and Toll-like receptor (TLR) protein signaling cascades.

31 insic behavior, free of complicated cellular signaling cascades.

32 tracellular matrix and triggering associated signaling cascades.

33 ons to regulate a multitude of intracellular signaling cascades.

34 classical receptor tyrosine kinase-activated signaling cascades.

35 e of ubiquitin-mediated regulation to refine signaling cascades.

36 regulatory network of apoptotic proteolytic signaling cascades.

37 ent for the targeting and initiation of many signaling cascades.

38 nds to "DNA sensors," which in turn initiate signaling cascades.

39 nterleukin-1 (IL-1)/Toll-like receptor (TLR) signaling cascades.

40 oteins to the membrane to activate oncogenic signaling cascades.

41 atically disentangle the effects of space in signaling cascades.

42 rs involved in multiple fundamental cellular signaling cascades.

43 ctivation of the ATM and CaMKII proapoptotic signaling cascades.

44 rs, locally amplifying ECM input to internal signaling cascades.

45 l-surface receptors to control intracellular signaling cascades.

46 and biological processes, such as intricate signaling cascades.

47 s, and regulation of inflammatory and immune signaling cascades.

48 abolic pathways, and activating inflammatory signaling cascades.

49 eby simplifying workflows in studies of cell-signaling cascades.

50 at intermediate nodes to deconvolve complex signaling cascades.

51 rotein complexes, and activation of multiple signaling cascades.

52 that although TP53 elicits vastly divergent signaling cascades across cell lines, it directly activa

53 One of the signaling cascades activated by nitro-fatty acids is the

54 mitogen-activated protein kinase Sty1-driven signaling cascade activates hundreds of genes to induce

55 methods are very effective for studying cell signaling cascade activation induced by external stimuli

56 stress activates the DNA damage response, a signaling cascade allowing cell cycle arrest and repair

57 These results identify an interspecies signaling cascade allowing ticks to detect invading bact

58 part of a complex, monoaminergic/peptidergic signaling cascade and appears to selectively inhibit neu

59 ing p41ARC as a new component of the insulin-signaling cascade and connecting PAK1 signaling to N-WAS

60 trol of the phototropin-dependent blue-light signaling cascade and correlated with the activity of th

61 rning this process, we here focus on the TCR signaling cascade and demonstrate that a rise in intrace

62 fic miRNAs which play a causal role in their signaling cascade and hence may regulate disease progres

63 the effects of LXA4 and BML-111 on the HMGB1 signaling cascade and inflammation in lipopolysaccharide

64 new regulatory layer of the Wnt/beta-catenin signaling cascade and provide new insight into SETD6 bio

65 ion, activation of an ILK/EGFR/Ras/NF-kappaB signaling cascade and subsequent Slug expression.

66 XS domain indicates an attenuation of the Pi signaling cascade and the up-regulation of genes involve

67 f the other members of the canonical beta2AR signaling cascade and, therefore, constitutes a novel si

68 The signaling cascades and energy-dissipating pathways that

69 eover, this approach dissects the downstream signaling cascades and facilitates identification of con

70 ntraction coupling, but also impacts diverse signaling cascades and influences the regulation of gene

71 ha) by initiating a variety of intracellular signaling cascades and is considered to be a key element

72 Additional studies have to address the signaling cascades and mechanistic processes that form t

73 ce of retinoschisin on Na/K-ATPase-regulated signaling cascades and Na/K-ATPase localization.

74 Whereas CDK8 is linked to specific signaling cascades and oncogenesis, the cellular roles o

75 Probing the molecular topology of complex signaling cascades and other heterogeneous networks is f

76 plants; however, the connection between MAPK signaling cascades and submergence tolerance is currentl

77 DAC6 in EMT via mediating the TGF-beta-Notch signaling cascade, and support HDAC6 as a key regulator

78 les supported the clinical relevance of this signaling cascade, and we propose that pharmacological a

79 ialic acid (SA)-involved signaling, the MAPK signaling cascade, and WRKY-involved transcriptional reg

80 ncluding the Raf/Mek/Erk and PI3K/Akt/mTORC1 signaling cascades, and also the WNT/beta-catenin pathwa

81 II IFNs share homology, expression patterns, signaling cascades, and antiviral functions with type I

82 ng Boolean response programs, multi-cellular signaling cascades, and self-organized cellular patterns

83 This study shows that a unique ligand and signaling cascade are used in immune cells to mount an i

84 pathophysiologic synaptic activity, multiple signaling cascades are activated that ultimately initiat

85 ogy have been key tools to identifying which signaling cascades are controlled by G proteins or beta-

86 While complex signaling cascades are known to be involved, it remains

87 therapeutic targets that modulate disrupted signaling cascades are of significant interest.

88 Heterotrimeric G protein signaling cascades are one of the primary metazoan sensi

89 nase mitogen-activated protein kinase (MAPK) signaling cascades are present in virtually all eukaryot

90 lecular mechanism linking both to left-right signaling cascades are unknown.

91 of actin-dependent growth cone steering, via signaling cascades, are well documented.

92 We show the STAT3-mediated IGF2/IGF-1R signaling cascade as a key modulator for both acquired a

93 signaling controls a conserved PDK-TORC2-Akt signaling cascade as part of a homeostasis network that

94 least in part, via inhibition of TLR4/MyD88 signaling cascade as well as inactivation of NLRP3 infla

95 d by the downstream effectors of cytoplasmic signaling cascades as well as translocation of the cytop

96 s via adhesion, and integrates intracellular signaling cascades associated with cytoskeleton dynamics

97 ession or pharmacological inhibition of this signaling cascade at multiple levels restored pigmentati

98 peripheral T cell survival depend on several signaling cascades, but whether a dedicated mechanism ex

99 ow that binding of sCD83 to MD-2 alters this signaling cascade by rapidly degrading IL-1R-associated

100 These findings uncover a signaling cascade by which starvation promotes autophagy

101 Individual steps of these signaling cascades can be targeted by specific intervent

102 e for an underappreciated mechanism by which signaling cascades can potentially affect growth cone tu

103 l cells are involved in the retina-to-sclera signaling cascade causing myopia.

104 These kinases act via a three-component signaling cascade comprising Mst1 and Mst2, the protein

105 entified the interferon pathway as the major signaling cascade consistently activated by trisomy 21 i

106 provides important clues regarding how these signaling cascades contribute to malignancy.

107 pled receptors (GPCRs), Gbetagamma-dependent signaling cascades contribute to specifying the spatiote

108 ) are ubiquitous lipid kinases that activate signaling cascades controlling cell survival, proliferat

109 eptors activate transcriptional networks and signaling cascades controlling the expression and activi

110 in interacting proteins control inflammatory signaling cascades could provide new pathways for therap

111 Targeted activation of signaling cascades coupled to mGluRIs in mice expressing

112 ese results implicate a novel ERK-S6K1-GluA1 signaling cascade critically involved in extinction.

113 integrins, thereby serving as a platform for signaling cascade cross-talk.

114 Hedgehog (Hh) pathway is a highly conserved signaling cascade crucial for cell fate determination du

115 potassium levels and other stimuli trigger a signaling cascade culminating in phosphoinositide-phosph

116 ed beta1 integrin levels and activation of a signaling cascade culminating in Slug induction, epithel

117 sm in which cholesterol depletion triggers a signaling cascade, culminating with contraction impairme

118 ent adenovirus (Ad.Mda-5) initiates multiple signaling cascades, culminating in cytotoxicity and type

119 Collectively, our findings describe a signaling cascade downstream of PDGF that sustains prone

120 formulated a computational model for a MAPK signaling cascade downstream of the EGF receptor to inve

121 xon ensheathment are facilitated by distinct signaling cascades downstream of Akt.

122 g assays, and inhibition of LRP6 or critical signaling cascades downstream of LRP6, including JNK and

123 Inflammatory signaling cascades downstream of TNF, TLR agonists, anti

124 the activation of the Hedgehog (Hh) and MET signaling cascades driving the epithelial-to-mesenchymal

125 nvolved, and reveal key contributors in this signaling cascade during human embryonic development.

126 ure of the intracellular effects that follow signaling cascades during early development and cell-res

127 sequent activation of Akt and its downstream signaling cascades (e.g. mTORC1) dominates the landscape

128 This signaling cascade enhanced the formation of an infectiou

129 tudies have elucidated the role of different signaling cascades, especially the DAF-16 cascade, on li

130 We found that mbGR/PLC/PKC signaling cascade exists in all cell types tested, sugge

131 e transforming growth factor beta (TGF-beta) signaling cascade (FBN1, TGFBR1, TGFBR2, TGFB2, TGFB3, S

132 stitutive activation of G protein downstream signaling cascades for some of the affected residues.

133 heir complex functions through activation of signaling cascades from receptors localized at the cell

134 ive regulator shared across STAT3 and mTORC2 signaling cascades, functioning as a tumor suppressor in

135 The interleukin (IL)-12 signaling cascade has been associated with primary bilia

136 Although several signaling cascades have been reported to be involved in

137 k1, that function at different levels of the signaling cascade; however, none have been identified th

138 hosphorylation, and activation of downstream signaling cascades, impacting neurite outgrowth and spin

139 t mutations of genes controlling the Rac/Rho signaling cascade important for proper migration and dif

140 The PI3K signaling cascade in APCs has been recognized as an esse

141 constitutive activation of the TAK1-NFkappaB signaling cascade in CD133(+) LSCs, and this program int

142 idation ligands and activating innate immune signaling cascade in platelets.

143 y acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chem

144 de a better understanding of phosphorylation signaling cascade in symbiosis.

145 the AWC neurons are thought to deploy a cGMP signaling cascade in the detection of and response to AW

146 uronal DAF-7/TGFbeta causes a DAF-1/TGFbetaR signaling cascade in the gonadal distal tip cell (DTC),

147 in regulating proteins in the insulin/IGF-1 signaling cascade in vivo in physiological states via th

148 fy SIK2 at the apex of the adipocyte-induced signaling cascades in cancer cells and make a compelling

149 ostimulation of protein kinase A and C-delta signaling cascades in conjunction with retinoic acid-ind

150 agement of G protein-coupled receptor (GPCR) signaling cascades in genetically defined GABAergic BNST

151 However, the impact of T21 on systemic signaling cascades in living individuals with DS is unde

152 ping Beauty transposons implicate additional signaling cascades in MPNST pathogenesis.

153 (gal3), are secreted proteins that initiate signaling cascades in several diseases, and recent human

154 , these findings indicate that JAK1-mediated signaling cascades in skin regulate the expression of pr

155 mong the different PDEs that coordinate cAMP-signaling cascades in these cells.

156 We show that this signaling cascade includes the small GTPase Arf6 and S6

157 transcription factor 1/2alpha (HIF-1/2alpha) signaling cascade including proteins involved in oxidant

158 n PDAC cells, leading to stimulation of HER2 signaling cascade, including ERK1/2, FAK, AKT and PAK1 a

159 ents are fine-tuned by a network of hormonal signaling cascades, including abscisic acid (ABA), ethyl

160 PTSD was also observed converging on common signaling cascades, including cytokine, innate immune, a

161 ated in the control of plasticity-associated signaling cascades, including Pten, Spred1, and Notch1.

162 eviewed here, multiple components of the RAS signaling cascade influence inflammatory cell phenotype

163 This inhibition is exerted both on the signaling cascade initiated by the lipopolysaccharide wi

164 herichia coli senses envelope stress using a signaling cascade initiated when DegS cleaves a transmem

165 in induction of distinct but interdependent signaling cascades instrumental in adaptive responses.

166 ion has addressed early steps in the insulin signaling cascade, insulin resistance in obesity seems t

167 are important downstream targets of a CSF-1 signaling cascade involved in myeloid development.

168 ultiple pathways, including stimulation of a signaling cascade involving AMP-activated protein kinase

169 In the case of starvation, a signaling cascade involving AMPK and histone deacetylase

170 ibition of TRPM3 channels occurs via a short signaling cascade involving Gbetagamma proteins, which f

171 tes an intrinsic pro-degenerative axon death signaling cascade involving loss of the NAD(+) biosynthe

172 process occurs via an MR-dependent, genomic signaling cascade involving SGK1 and a functioning TRPM7

173 Here, we identify a new neuroprotective signaling cascade involving the activity-induced transcr

174 Activation of the PI3K-AKT signaling cascade is a common critical event during mali

175 The NF-kappaB signaling cascade is comprised of two branches, the cano

176 neurons and conclude that an ETH-JH-dopamine signaling cascade is required during a critical period f

177 ically, our data indicate that the NF-kappaB signaling cascade is significantly upregulated in Nlrx1(

178 he biological importance of a WHSC1-mediated signaling cascade is substantiated by patient sample ana

179 Whereas the vertebrate JAK/STAT signaling cascade is transduced via multiple receptor co

180 Temporal and spatial control of these signaling cascades is achieved through networks of regul

181 ey act downstream of separate or overlapping signaling cascades is still unclear.

182 network (MEN), an essential Ras-like GTPase signaling cascade, is inhibited by the spindle position

183 though TLR TIR is central to a number of TLR signaling cascades, its role in sensory neurons is poorl

184 It operates a mechanosensitive signaling cascade known as the spindle assembly checkpoi

185 Although many LC8-interactors have roles in signaling cascades, LC8's role in developing epithelia i

186 In apoptotic cells, caspase-initiated signaling cascades lead to the downstream production of

187 ol of the gain of spike firing depended on a signaling cascade leading to extracellular signal-relate

188 ase 1)-IRF3 (interferon regulatory factor 3) signaling cascade leading to IFN-beta production and the

189 tical contractility during mitosis through a signaling cascade leading to multipolar divisions, and i

190 promoting a protein kinase A (PKA)-dependent signaling cascade leading to phosphorylation of serine S

191 rs P2Y1 and P2Y12, stimulating intracellular signaling cascades, leading to integrin alphaIIbbeta3 ac

192 n to prompting a diverse range of downstream signaling cascades, LFA-1 stimulation in T lymphocytes m

193 e data showing that AGE induces several cell signaling cascades, like NF-kappaB, PKC, ERK, and MAPK,

194 ignaling pathway; however, the early nuclear signaling cascade linking DNA damage and NF-kappaB activ

195 This signaling cascade may be relevant to other diseases invo

196 ive oxygen species-triggered LKB1/CaMKK-AMPK signaling cascade may provide a quick, adaptable switch

197 the possibility that MOR and its downstream signaling cascades may be novel targets for antidepressa

198 Consequently, these signaling cascades may represent potential therapeutic t

199 s take into account the dynamic responses of signaling cascades measured from in vivo cellular system

200 -irradiated cells also activate a checkpoint signaling cascade mediated by the ATM and Rad3-related (

201 The innate immune inflammasome signaling cascade mediates the production of essential p

202 , pathophysiologic activity can also trigger signaling cascades mediating potentially compensatory ne

203 These Tec kinases are involved in signaling cascades mediating T-lymphocyte proliferation,

204 ceptor genes, upstream effectors of the MAPK signaling cascade, might be novel target genes for pain

205 proteins in the RLR, NLR, and TLR antiviral signaling cascades modulate IFN-I expression.

206 rotein Tau, has been shown to participate in signaling cascades, modulate microtubule dynamics, and p

207 acellular ligands to transduce intracellular signaling cascades, modulate target gene expression, and

208 The mechanistic target of rapamycin (mTOR) signaling cascade modulates experience-dependent synapti

209 result in the preferential activation of one signaling cascade more than another.

210 negatively regulates the NF-kappaB pathway-a signaling cascade necessary for HIV-1 replication and in

211 tro, baicalein down-regulated the TLR4/MyD88 signaling cascades (NF-kappaB and MAPKs) in lipopolysacc

212 ng to the Crk family that is involved in the signaling cascade of IL-2, stromal cell-derived factor 1

213 In this study, we report a bifurcation in a signaling cascade of the NIMA-related kinases (Neks) Nek

214 ith reduced side effects have focused on the signaling cascades of the mu-opioid receptor (MOR).

215 ders, such as autism and schizophrenia, this signaling cascade offers new avenues to modulate synapti

216 e role of KORs and KOR-coupled intracellular signaling cascades on reinstatement of nicotine CPP.

217 distinguishes two separate Abetao-dependent signaling cascades, one dependent on extracellular Ca(2+

218 es such that alpha-arrestins, stimulated via signaling cascades or in their basal state, recognize tr

219 the results together, this work depicts the signaling cascades orchestrating Rps6 phosphorylation in

220 he cyclooxygenase-2 (COX-2)/prostaglandin E2 signaling cascade (phospholipase A2, COX-2, multidrug re

221 and cross-talk between proteins within these signaling cascades potentiate IFN-I expression, and inve

222 ctivation of c-Jun NH2-terminal kinase (JNK)-signaling cascades, pro-inflammatory effectors/cytokines

223 the calcineurin/NFAT, FasL/Fas, and caspase signaling cascades promote neonatal pig GMC apoptosis.

224 model for GBM are enriched for intracellular signaling cascade proteins (GO: 0007242) and Ras protein

225 +) leakage, or blocking the beta2-adrenergic signaling cascade reduced betaAPP processing and the pro

226 It is implicated as suppressed TCR-signaling cascades, reduced alterations in activation ma

227 These results reveal that different signaling cascades regulate cerebral blood flow at the c

228 The partially understood phosphoinositide signaling cascade regulates multiple aspects of cellular

229 This signaling cascade regulates the fate of its targets thro

230 The NF-kappaB signaling cascade relays external signals essential for

231 Therefore, the AKT/WHSC1/mTORC2 signaling cascade represents a vicious feedback loop tha

232 Notch and ERBB are evolutionarily conserved signaling cascades required for the maintenance of melan

233 translational efficiency via an AKT/HSF1/HuR signaling cascade resulting in enhanced mTORC2 activity

234 in of RAGE initiates a complex intracellular signaling cascade, resulting in the production of reacti

235 cursor cells, RIT1 controls an Akt-dependent signaling cascade, resulting in the stabilization and tr

236 ropic glutamate receptors (mGluRs) activates signaling cascades, resulting in calcium release from in

237 ilencing of major inflammatory intracellular signaling cascades (STAT1, STAT3, STAT5, p38, and ERK1/2

238 lts demonstrate that targeting the BRD4-p300 signaling cascade supports the generation of superior an

239 wnstream of Abeta through a beta2-adrenergic signaling cascade that activates PKA.

240 messenger in phototransduction, a G-protein signaling cascade that conveys photon absorption by rhod

241 -HETE binds and through which it activates a signaling cascade that culminates in many of the functio

242 CLV3 ligand/CLV1 receptor system initiates a signaling cascade that elevates cytosolic Ca(2+), and th

243 The Wnt signaling pathway is one such signaling cascade that enables hepatic homeostasis and c

244 RIG-I like receptor family, that activate a signaling cascade that induces IFN production.

245 p1 in promoting the dermal papilla inductive signaling cascade that initiates HF growth.

246 s (PRRs) of infected cells, which triggers a signaling cascade that initiates innate intracellular an

247 an essential node within the RAS/RAF/MEK/ERK signaling cascade that is commonly activated by oncogeni

248 rovides insight into a non-canonical TGFbeta signaling cascade that is responsible for inducing EMT b

249 Aberrant PAD exposure induces a signaling cascade that leads to disruption of axonal tra

250 aining adaptor protein (TIRAP), triggering a signaling cascade that leads to innate immune responses.

251 tor neurons (ORNs) involves primarily a cAMP-signaling cascade that leads to the opening of cyclic-nu

252 The MEN is a signaling cascade that localizes to spindle pole bodies

253 independent GOF mutant p53-AMPK-FOXO3a-FOXM1 signaling cascade that plays an important role in mediat

254 Cumulatively, we identify a signaling cascade that provokes structural remodeling of

255 4-1BB ligation on T cells triggers a signaling cascade that results in upregulation of antiap

256 idopsis (Arabidopsis thaliana), triggering a signaling cascade that shares some similarities to respo

257 sphatidylinositol 4,5-bisphosphate-dependent signaling cascade that suppresses persistent activity.

258 ds, but they also participate in the ensuing signaling cascades that allow skeletal muscle to adapt t

259 essive pathways, as well as mechanosensitive signaling cascades that are activated by increased tissu

260 rtain growth factors but also the fine-tuned signaling cascades that are initiated by hypoxia.

261 We report that signaling cascades that are traditionally viewed as coag

262 d places recombination within the context of signaling cascades that control B cell development.

263 olytopic membrane proteins impacts the redox signaling cascades that control cell proliferation and d

264 ues in receptor tyrosine kinases and trigger signaling cascades that control critically important cel

265 egrins by the extracellular matrix initiates signaling cascades that drive a variety of cellular func

266 how passive and active forces induce similar signaling cascades that drive self-renewal, migration, d

267 Signaling cascades that localize to cholesterol-rich reg

268 Stress-activated MAP kinase signaling cascades that mediate cytokine synthesis are w

269 However, the intracellular signaling cascades that mediate the osteoblastogenic fun

270 However, the precise signaling cascades that mediate the TNF-alpha-induced ac

271 t roles in the initiation and progression of signaling cascades that regulate cell functions.

272 ructure of distinct scaffolds induces unique signaling cascades that regulate migration and morpholog

273 pathway, a common final pathway for multiple signaling cascades that regulate the actin cytoskeleton,

274 e postsynaptic neuron and trigger downstream signaling cascades that regulate the synaptic state.

275 verned by combinatorial inputs from numerous signaling cascades that ultimately dictate lineage-speci

276 erated asymmetric fluid flow, resulting in a signaling cascade - the Nodal-Pitx2 pathway - being robu

277 As a core signaling cascade, the canonical Wnt pathway is regulate

278 critical proteins of the NF-kappaB and MAPK signaling cascade, thereby blocking inflammatory cytokin

279 APP-CTF accumulation initiates CREB signaling cascade through an association of APP-CTF with

280 ereas targeted DNMT1 depletion abrogates KIT signaling cascade through Sp1/miR-29b network.

281 This work describes how C1P activates a signaling cascade to dynamically regulate P-glycoprotein

282 OCK5-dependent activation of the Crk-p130Cas signaling cascade to promote Rac1-mediated lamellipodial

283 where its overexpression activates multiple signaling cascades to promote malignant progression and

284 (miRNAs) - which are critical regulators of signaling cascades - to identify so far uncharacterized

285 d JNK mitogen-activated protein (MAP) kinase signaling cascades trigger specific cellular responses a

286 approach, we identified a robust and diverse signaling cascade triggered by HIV-1 upon entry into hum

287 ng at the Golgi, where betagamma activates a signaling cascade, ultimately resulting in vesicle fissi

288 ional methods can help rescue disruptions in signaling cascades underlying memory formation.

289 ce of T lymphocytes that initiates cytosolic signaling cascades upon binding antigens presented by MH

290 an upstream component of the integrin Tyr(P) signaling cascade, was diminished in GIV-depleted cells,

291 of inhibitors against components of the TCR signaling cascade, we demonstrate that Notch activation

292 togen-activated protein (MAP) kinase (MAK-1)-signaling cascade, whereas a second MAP kinase pathway (

293 egulation can lead to changes in the insulin signaling cascade, which can translate to insulin resist

294 on in activating an evolutionarily conserved signaling cascade, which ensures that continuous uptake

295 These factors are regulated via a signaling cascade, which includes mobile EPIDERMAL PATTE

296 on-dependent cell proliferation is the Hippo signaling cascade, which is coregulated by the transcrip

297 ponses mediated through the PI3K/TOR or MAPK signaling cascades, which act to protect the parasite fr

298 Activation of signaling cascades, which mediate inflammasome responses

299 llular signal-regulated kinase (ERK) protein signaling cascade within the brain is crucial for optima

300 specifying and cell-polarizing intracellular signaling cascades, Wnts can polarize cells at their sit