ライフサイエンスコーパス: signaling pathway

1 ntrols angiogenesis, the Norrin-beta-catenin signaling pathway.

2 ssing the adaptive unfolded protein response signaling pathway.

3 f ATP signaling and activation of the ERK1/2 signaling pathway.

4 pecifically binds IL-1alpha and inhibits its signaling pathway.

5 ulation of components of the Cxcr4-chemokine signaling pathway.

6 d ETR2 do not require the canonical ethylene signaling pathway.

7 how that this aptamer inhibits the IL-1alpha signaling pathway.

8 independent but EGFR- and integrin-dependent signaling pathway.

9 nes with aberrant activation of the Hedgehog signaling pathway.

10 downstream effectors of the Ras/Raf/MEK/ERK signaling pathway.

11 tion by manipulating the IDL6-HAE/HSL2-ADPG2 signaling pathway.

12 Wallenda (Wnd)/DLK MAP kinase axonal damage signaling pathway.

13 ral component of the NPM-ALK-dependent actin signaling pathway.

14 d scaffolding protein in the T-cell receptor signaling pathway.

15 activation of downstream sensors in the RLR signaling pathway.

16 without stimulation of the proximal insulin signaling pathway.

17 ryonic polarity and regulating the NF-kappaB signaling pathway.

18 amily members are influenced by this hormone signaling pathway.

19 type 1 (AGTR1), in the Ca2+/AT-IIR/alpha-AR signaling pathway.

20 tasis via Akt(S437) phosphorylation mediated signaling pathway.

21 ory role for embryonic myosin in the TGFbeta signaling pathway.

22 ns in the nuclear factor kappa B (NF-kappaB) signaling pathway.

23 ostasis through the Paneth cells and the Wnt signaling pathway.

24 genes GPC4 and RAC3, both linked to the Wnt signaling pathway.

25 liferation of PDGFRalpha+ cells via PI3K/Akt signaling pathway.

26 riation in 40 of 41 genes comprising the NOD signaling pathway.

27 ion in the murine lung via a TLR2/TLR4/MyD88-signaling pathway.

28 cogenic dependency from the BCL-2 to the ERK signaling pathway.

29 tivating a Calcineurin-FoxO-MuRF1-proteosome signaling pathway.

30 ell growth involves inhibition of the p70S6K signaling pathway.

31 , receptor 1 (TRPV1)-substance P nociceptive signaling pathway.

32 addition to thiol-containing proteins in key signaling pathways.

33 TU suppressed the Emax insurmountably in all signaling pathways.

34 ll as downregulation of extracellular matrix signaling pathways.

35 mediated through differential or synergistic signaling pathways.

36 sively to understand the selectivity of GPCR signaling pathways.

37 g the control of apoptosis with the relevant signaling pathways.

38 ntial role in propagating TNF-alpha-mediated signaling pathways.

39 icipates in crosstalk between these critical signaling pathways.

40 e by upregulating critical cancer-associated signaling pathways.

41 ions, which, in turn, may reveal further Wnt signaling pathways.

42 ylic acid- and jasmonic acid-related defense signaling pathways.

43 at can cleave extracellular matrix and alter signaling pathways.

44 Rs) are central to many fundamental cellular signaling pathways.

45 sias often due to interacting or overlapping signaling pathways.

46 like receptors and pro-inflammatory cytokine signaling pathways.

47 be correlated to restoration of ERK and AKT signaling pathways.

48 inking phagosomal maturation to specific TLR signaling pathways.

49 1-cyto expression in HMECs induced NF-kappaB signaling pathways.

50 and interleukin 1 receptor (IL-1R) mediated signaling pathways.

51 ns 273 scaffold proteins and 1118 associated signaling pathways.

52 n if they are mediated by shared or distinct signaling pathways.

53 ction of allosteric interaction networks and signaling pathways.

54 rmations to respond to regulatory signals in signaling pathways.

55 rom mouse tracheas were assayed in vitro for signaling pathways.

56 ccording to a mechanism involving endogenous signaling pathways.

57 iles accumulating in GPCR, PI3K-Akt and FGFR signaling pathways.

58 bolic, transport, genetic, developmental and signaling pathways.

59 associated with alterations in intracellular signaling pathways.

60 disease virulence through disruption of host signaling pathways.

61 onses to various signals and crosstalk among signaling pathways.

62 ndicated an upregulation of "Axonal Guidance Signaling" pathway.

63 Down-regulation of the ARP2/3 complex signaling pathway, a common final pathway for multiple s

64 cytosolic immune responses through the STING signaling pathway, although evidence suggests that alter

65 eta is an established regulator of the Notch signaling pathway, although its mechanism of action rema

66 associated unique abnormalities in cellular signaling pathways amenable to directed therapies.

67 , we find that a recognized growth-promoting signaling pathway amplifies the F-actin disassembly and

68 attenuated the upregulation of the TGF-beta signaling pathway and alpha1-antitrypsin protein (a seri

69 phenotypes restore sensitivity to the mTORC1 signaling pathway and cause death, indicating that persi

70 tion of mammalian target of rapamycin (mTOR) signaling pathway and inhibition of glycogen synthase ki

71 ified, and connections between the symbiosis signaling pathway and key transcriptional regulators tha

72 cer and activator of transcription 3 (STAT3) signaling pathway and negated by TLR4-specific antibody

73 ion, involvement of the Akt/WNT/beta-catenin signaling pathway and relevant phosphatases in VE-cadher

74 t the functional plasticity of the NF-kappaB signaling pathway and underscores the need for more sele

75 genously in vivo and has multiple effects on signaling pathways and cell function.

76 NSPs) that play roles in the control of cell-signaling pathways and defense against pathogens and who

77 in this study between cell-specific dynamic signaling pathways and drug sensitivity.

78 released from multiple cells engage distinct signaling pathways and effector systems across the entir

79 TCR induced a rapid expression of apoptotic signaling pathways and formation of embryonic gene clust

80 n is sufficient to activate BCR and PI3K/Akt signaling pathways and further enhances signaling follow

81 earlier work linking the immune and insulin signaling pathways and identify new targets of insulin s

82 regulated is important for elucidating cell signaling pathways and identifying new targets for treat

83 However, inter-dependence between these signaling pathways and key mucosal barrier components in

84 This can be a challenge, since signaling pathways and ligands are commonly used at mult

85 We identified alterations in signaling pathways and proteins with related functions,

86 s, called effectors, to manipulate host cell signaling pathways and subvert host defense mechanisms.

87 toxin functions to specifically impair host signaling pathways and suggest a general strategy for ma

88 c progression of HCC by integrating multiple signaling pathways and suggest that Gab2 might be a powe

89 d endocrine systems, by influencing cellular signaling pathways and sulfhydration of target proteins.

90 ent of this association involves a number of signaling pathways and transcriptional responses between

91 These findings uncover a new Ssp1-Kin1 signaling pathway, and define its functional and mechani

92 des by activating the TIR-1 - JNK-1 - DAF-16 signaling pathway, and the cell wall component of BB68 c

93 ntial to differentiate the respective roles, signaling pathways, and phenotypic outcomes of hUII and

94 adrenergic signaling, cross-talk with other signaling pathways, and the effects of betaAR-directed d

95 ptor internalization, regulation of distinct signaling pathways, and transcriptional regulation.

96 urotransmitter systems through intracellular signaling pathways-and may unify a number of currently c

97 Surprisingly, what signaling pathways are active in the basal state and the

98 nally, we identified that NF-kappaB and MAPK signaling pathways are both involved in the process of I

99 Cytokine-mediated intracellular signaling pathways are fundamental for the development,

100 nrichment analysis (GSEA) indicated multiple signaling pathways are involved DKD pathogenesis.

101 Wnt signaling pathways are of significant interest in develo

102 le resource for understanding how individual signaling pathways are regulated.

103 activation of epithelial NF-kappaB and PI3K signaling pathways are restricted by the M-ILK deficienc

104 uppressive activities by PKC-theta and Dlgh1 signaling pathways are shared.

105 reviously uncharacterized IGF1-RIT1-Akt-Sox2 signaling pathway as a key component of neurogenic niche

106 SNHG1 was involved in the AKT signaling pathway as it promotes the neighboring transcr

107 cluding activation of the p38 MAPK-C/EBPbeta signaling pathway as well as the ubiquitin-proteasome an

108 umber of candidate genes involved in the ABA signaling pathway, as well as transcription factors, tra

109 (mTOR), proinflammatory, and anti-apoptotic signaling pathways, as well as downregulation of extrace

110 se and phospho-AKT serine/threonine kinase 1 signaling pathways, as well as increased total and activ

111 bowel diseases is driven by the inflammatory signaling pathways associated with mucosal epithelial da

112 ng vascular endothelial growth factor (VEGF) signaling pathways at concentrations too low to be detec

113 provides an easy and systematic way to study signaling pathways at the single-cell level.

114 Tumor biopsies showed decreases in cell-signaling pathways (Bcl-2, Bcl-6, c-Myc), reduced prolif

115 To infer when during evolution signaling pathways became associated with cilia, we char

116 By aberrantly activating the RAF-MEK-ERK signaling pathway, BRAF-V600E shapes key biologic featur

117 avior by participating in a seemingly simple signaling pathway, but outcomes produced by Notch signal

118 kappaB-mediated inflammatory and tumorigenic signaling pathways can explain the absence of hepatic tu

119 The major endoplasmic reticulum stress signaling pathway causing cardiac hypertrophy involves e

120 hepatic AMPK/sirtuin-1 and FGF21/beta-klotho signaling pathways combined with down-regulation of STAT

121 in transcript levels of elements of several signaling pathways considered critical for diapause regu

122 Thus, we hypothesized that the JNK/c-Jun signaling pathway contributes to TNBC tumorigenesis.

123 Here, we identify a novel signaling pathway contributing to IL-8 secretion in the

124 hosis and HCC, but the molecular players and signaling pathways contributing to these processes remai

125 to coordinate an IL6-dependent AMPK nuclear signaling pathway converging on FoxO3 transcription fact

126 findings provide novel information regarding signaling pathways coordinating central control of whole

127 e-B-cell receptor and interleukin 7 receptor signaling pathways critical to B-cell development (with

128 mber of the Bone Morphogenetic Protein (BMP) signaling pathway, Decapentaplegic (Dpp), specifically i

129 rain-region-specific neural progenitor-based signaling pathway dedicated to regulating GM vessel deve

130 ate, through activation of the PTEN/PI3K/Akt signaling pathway, different molecules involved in apopt

131 ding on the cell type, expression level, and signaling pathway downstream of this receptor.

132 treatment, and a better understanding of the signaling pathways downstream of PD-1 could provide biom

133 Deregulation of the Wnt/beta-catenin signaling pathway drives the development of colorectal c

134 a crucial role in metabolic, regulatory, and signaling pathways, due in part to the high tunability o

135 bB4-induced phosphorylation of the canonical signaling pathway effectors Erk1/2, Akt, or STAT5 nor Er

136 To search for signaling pathways enriched in muscle of ICU-acquired we

137 As the primary cilium coordinates several signaling pathways essential for odontogenesis, ciliary

138 a specific context by receptors to initiate signaling pathways for engulfment.

139 trated that the TGF-beta and IL-6/JAK2/STAT3 signaling pathways form a positive feedback signaling lo

140 How signaling pathways function reliably despite cellular va

141 During human brain development, multiple signaling pathways generate diverse cell types with vari

142 The RTK/ERK signaling pathway has been implicated in prostate cancer

143 geted therapies specific to the BRAF-MEK-ERK signaling pathway have shown great promise in the treatm

144 Both signaling pathways have been predicted previously using

145 This study proposes CTC biomarkers and signaling pathways implicated in BCBM that may be used e

146 Examination of TLR signaling pathways implicated the canonical NF-kappaB pa

147 calcium ions (Ca2+) represents a fundamental signaling pathway in all eukaryotic cells.

148 inc-induced cancer prevention and Orai1-SOCE signaling pathway in cancer cells.

149 gated the molecular role of Wnt/beta-catenin signaling pathway in reparative dentinogenesis using an

150 Light and ACh share a common signaling pathway in sphincter muscle.

151 Activation of the nodulation signaling pathway in spontaneously nodulating mutants wa

152 These data help to develop a new signaling pathway in the regulation of steroid hormones

153 logous phosphatases that negatively regulate signaling pathways in a number of hematopoietic lineages

154 growth factor 21 (FGF21), and activation of signaling pathways in adipose tissue.

155 t implications for interventions that target signaling pathways in angiogenesis relevant to cancer, v

156 h have been shown to be involved in numerous signaling pathways in Arabidopsis.

157 has been shown to inhibit numerous oncogenic signaling pathways in cancer cells.

158 ceptor-mediated proliferation and cell death signaling pathways in different tumor types and presents

159 e alterations in protein phosphorylation and signaling pathways in pancreatic cancer cells after gemc

160 and imaging strategies directed at aberrant signaling pathways in pancreatic tumor cells may improve

161 ownregulated RTK, mTOR, and Wnt/beta-catenin signaling pathways in premalignant mammary tissues.

162 cells, whether it directly engages nutrient signaling pathways in skeletal muscle to maintain system

163 HBoV1 takes advantage of signaling pathways in the DNA damage response for effici

164 tion clock) driving the rhythmic activity of signaling pathways in the presomitic mesoderm (PSM).

165 nd inflammation including NF-kappaB and Nrf2 signaling pathways in the retina which may contribute to

166 roles of NFIC-dependent and NFIC-independent signaling pathways in tooth root formation.

167 IL-6/IL-6R signaling pathway, in particular, has been proposed to b

168 upregulation of a number of hypoxia mediated signaling pathways including cell proliferation, metabol

169 es and apoptosis at the wound healing stage, signaling pathways including Wnt and TGFbeta during earl

170 iple cellular processes and enzyme-regulated signaling pathways, including chromatin modifications an

171 13 also linked SMYD2 to other PKD-associated signaling pathways, including ERK, mTOR, and Akt signali

172 that they can activate a range of downstream signaling pathways, including MAP kinase and Akt.

173 stability along with upregulation of several signaling pathways, including the cytokine-cytokine rece

174 h and survival via activation of MM survival signaling pathways, including the MEK-extracellular sign

175 athway has cross-talk with several other key signaling pathways, including the PI3K/Akt/mTOR and MAPK

176 idly activate intracellular second-messenger signaling pathways independently of gene expression (non

177 t of the well-studied heat shock and insulin signaling pathways, indicating that the IPR is a distinc

178 gs that inhibit important kinases in the BCR signaling pathway inhibit activation of lytic viral expr

179 ligand (RANKL), sclerostin, and Dickkopf Wnt signaling pathway inhibitor 1 levels.

180 This study elucidated a novel cytoprotective signaling pathway initiated by the APP transcriptionally

181 Calcium-dependent signaling pathways initiated by store-operated calcium e

182 ial-to-mesenchymal transition and the ERK1/2 signaling pathway inversely affected by miR-519d or EphA

183 diseases such as atopic dermatitis, but the signaling pathways involved are unclear.

184 ically diverse malignancy, and new genes and signaling pathways involved in pathogenesis continue to

185 ed sensitization of the channel to stimulate signaling pathways involved in regulating skin homeostas

186 Signaling pathways involved in stiffness-mediated podocy

187 Based on these results, we propose that signaling pathways involved in structural plasticity lik

188 ents and further identify the cell types and signaling pathways involved in this process.

189 inhibition of the RIG-I-like receptor (RLR) signaling pathway involves inhibition of RIG-I K63-linke

190 in-releasing pancreatic beta cells through a signaling pathway involving the second messenger cyclic

191 Identifying specific signaling pathways involving Abeta has allowed for the d

192 a tool for optogenetic manipulation of cell-signaling pathways involving cyclic nucleotides.

193 3K-protein kinase B (PKB; also known as Akt) signaling pathway is a central axis in mediating proxima

194 mouse infection models, we show that the SIP signaling pathway is active during infection and contrib

195 The activin signaling pathway is an attractive candidate to fulfill

196 normal palatal tissues and that the Eda/Edar signaling pathway is downstream of Pax9 in palatogenesis

197 The NETRIN1 signaling pathway is identified as a candidate pathway f

198 Our results also suggest that the SA signaling pathway is involved in CP-mediated plant defen

199 tion of the presence of WNV through the MAVS signaling pathway is not required for generation of effe

200 Although the canonical Notch signaling pathway is well characterized, accumulating ev

201 However, understanding of cAMP signaling pathways is hindered by the presence of at lea

202 eonine phosphatases integrate with G protein signaling pathways is less understood.

203 in blood oxygenation with those in neuronal signaling pathways is missing.

204 f important molecular components of the TGFB signaling pathway, it is likely that interactions remain

205 metric to study information transmission in signaling pathways, it does not capture the overlap betw

206 Although much is known about the underlying signaling pathways, it remains unclear how macroscopic f

207 When it is depleted, specific signaling pathways leading to antiviral effectors are af

208 was shown to be interference with the lipid signaling pathway, leading to reduced expression of MDR

209 led to the recognition of distinct neuronal signaling pathways linking Abeta to synaptotoxicity and

210 ng the last years in understanding the SnRK1 signaling pathway, many of its components remain unident

211 are routinely used for clinical analysis of signaling pathways, mass spectrometry-based approaches s

212 Targeting fibrinogen or its downstream BMP signaling pathway may help with CNS repair.

213 Taken together, we propose that RR and its signaling pathway may serve as novel actionable targets

214 s or agonists that target these chemosensory signaling pathways may be considered as new therapeutic

215 y (TBI), suggesting that stimulation of BDNF signaling pathways may facilitate functional recovery.

216 three agonists in a parallel manner for all signaling pathways measured.

217 ns was a result of activation of alternative signaling pathways mediated by factors secreted by BM st

218 However, whether this ubiquitin signaling pathway mediates Abeta-induced loss of surface

219 1, 0007155) and pathways in cancer, PI3K-Akt signaling pathway, metabolic pathways (pathway IDs: 5200

220 to be spatially regulated through two myosin-signaling pathways, myosin light chain kinase and Rho-as

221 ylation of components of the hepatic insulin-signaling pathway, namely IRS1, Akt, and GSK3, was decre

222 e results also provide new evidence that the signaling pathway of cellular MKK2 phosphorylation plays

223 We now show that in AAV-NT mice, the signaling pathways of the CR mediators, AMP-activated pr

224 This unconventional signaling pathway offers an innovative therapeutic targe

225 e improved understanding of the beta-catenin signaling pathway over the past three decades, attempts

226 F-kappaB1/p50 gene and inhibit the NF-kappaB signaling pathway (p-P65 downward arrow, NF-kappaB1/p50

227 reciprocal feedback between AR and PI3K/AKT signaling pathways, pAKT levels were increased in androg

228 ng substrates and activation of the cAMP/pkA signaling pathway play a key role in spontaneous lizard

229 vel transcriptional coactivator of the Notch signaling pathway, playing an important role in neural s

230 The hedgehog (Hh) signaling pathway plays a central role during embryonic

231 dence demonstrates that the Wnt/beta-catenin signaling pathway plays a dominant role in bone repair.

232 Aberrant activation of the Wnt signaling pathway plays an important role in human cance

233 Accordingly, stem cell-specific oxygen signaling pathways precisely control the balance between

234 icant because the canonical Wnt/beta-catenin signaling pathway promotes neurogenesis and inhibits neu

235 maturation through the cytoplasmic gelsolin signaling pathway, providing new drug targets for the tr

236 These results suggest that an active ET signaling pathway reduces root attractiveness to SCN in

237 animal kingdom, it is unknown whether common signaling pathways regulate the development of neuronal

238 In an attempt to identify novel actin signaling pathways regulated by NPM-ALK, a comprehensive

239 The Reelin-Dab1 signaling pathway regulates development of the mammalian

240 we show that the butterfly-shaped TIPRL (TOR signaling pathway regulator) makes highly integrative mu

241 sity lipoprotein receptor), while the APOER2 signaling pathway remains active, which accounts for the

242 R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia o

243 Interestingly, inhibiting the TOR signaling pathway rescued the midgut defects of the Atg9

244 entiation of Langerhans cells, delineate the signaling pathways responsible for each phase of the hai

245 mine triggered the Akt-nitric oxide synthase signaling pathway, resulting in time- and isoform-specif

246 Signaling pathways (retinoic acid, sonic hedgehog, and N

247 ents of the Bone Morphogenetic Protein (BMP) signaling pathway, revealing that BMP signaling inactiva

248 ted with S100A4 elevation, defining required signaling pathway(s) for S100A4 in this setting.

249 In a signaling pathway screen, lysophosphatidic acid increase

250 concurrent blockage of the NF-kappaB and Akt signaling pathways sensitizes lung cancer cells to cispl

251 ng genetic aberrations that impair the Hippo signaling pathway showed heightened sensitivity to gemci

252 AP4Ks as important regulators of the DLK/JNK signaling pathway.SIGNIFICANCE STATEMENT Neuronal degene

253 tein kinase 1 (MSK1)-ranges of intracellular signaling pathways similar to those activated by opioid

254 rts mutational testing for genes in the EGFR signaling pathway, since they provide clinically actiona

255 The EGF signaling pathway specifies neuronal identities in the D

256 significance, as therapeutic targeting of a signaling pathway such as NG2/CSPG4 may have different e

257 ale that is inconsistent with canonical trkB signaling pathways, suggesting a noncanonical role for t

258 esign of rational cytokine and intracellular signaling pathway-targeted therapeutics, reviewed herein

259 Here, we characterize a novel signaling pathway that can be targeted to inhibit the se

260 cidate a novel RARbeta-TET2-miR-200c-PKCzeta signaling pathway that directs cancer cell state changes

261 At the core of trans-Tango is a synthetic signaling pathway that is introduced into all neurons in

262 ns are the downstream effectors of the Hippo signaling pathway that regulate cell proliferation and s

263 an target of rapamycin complex 1 (mTORC1), a signaling pathway that regulates synaptic protein synthe

264 S339-CXCR4 in order to activate a PREX1-Rac1-signaling pathway that stabilizes interleukin-2(IL-2), I

265 yme involved in protein degradation affect a signaling pathway that stimulates the development of the

266 LTCCs) in the plasma membrane can initiate a signaling pathway that ultimately increases nuclear CREB

267 zing AMPK to allosteric drugs, and activates signaling pathways that appear independent of Thr172 pho

268 activin and TGF-beta are strongly connected signaling pathways that are important in advanced CRC.

269 ets of which were enriched for intracellular signaling pathways that are important to coordinating in

270 5, resulting in the activation of downstream signaling pathways that have been linked to pro-nocicept

271 ity and an obese tumor microenvironment with signaling pathways that predict aggressive breast cancer

272 mily of nonreceptor tyrosine kinases acts in signaling pathways that regulate cell migration, cell ad

273 al and homing characteristics exist, but the signaling pathways that regulate their development are i

274 identified multiple candidates in many cell signaling pathways that were able to mediate significant

275 nscriptomic analysis identified numerous key signaling pathways that were differentially expressed be

276 These purinoreceptors and the signaling pathways they activate have been identified as

277 ere found to be involved in pAkt - NF-kappaB signaling pathway through a reduction in phosphorylation

278 Promotion of AD-related signaling pathways through this mechanism may contribute

279 he blockade of the HER2-pY(1196)-PAK1-T(423) signaling pathway, thus increased tumor cell motility.

280 s, many of which signal through the JAK/STAT signaling pathway to exert their biological effects.

281 llular ATP signaling directly impacts the JA signaling pathway to maximize plant defense responses.

282 progenitors, we found activation of the Wnt signaling pathway to promote neurogenesis of the ENS in

283 x network with serotonergic and neuropeptide signaling pathways to control food-regulated behavioral

284 n upstream regulators of the TORC1 and TORC2 signaling pathways to coordinate cellular stress respons

285 edgehog (Gli1, Ptch1, SMO), and mTOR (pS6K1) signaling pathways to determine the mechanism of action

286 hat target angiotensin II-dependent NFkappaB signaling pathways to improve the treatment of this brea

287 to IL-32beta and also IL-6, IL-8, and CXCR1 signaling pathways to reverse the proapoptotic effect of

288 A signaling pathway transmits information from an upstream

289 However, the intracellular signaling pathway triggering Src activation of IRF4 rema

290 of a variety of genes and identify multiple signaling pathways underlying taste cell differentiation

291 etween the mRNA capping machinery and the Hh signaling pathway, unveils a new facet of Hh signaling r

292 Nitro-fatty acids can modify specific signaling pathways via post-translational modifications

293 This signaling pathway was required for both the early and la

294 ave in part described this systemic-to-brain signaling pathway, we lack information on how these chan

295 fusions activate both the MAPK and PI3K/mTOR signaling pathways, we identify combinatorial inhibition

296 cies, autophagy activation and intracellular signaling pathways were analyzed in Mincle-sufficient an

297 antagonism patterns could vary in different signaling pathways, which could be related to conformati

298 By screening TAK1-associated signaling pathways with inhibitors and siRNAs, we found

299 types via distinct classical and alternative signaling pathways, with implications for improved under

300 EVs secreted by AFSC could target a specific signaling pathway within the glomerulus, thus representi