ライフサイエンスコーパス: signaling through

1 in is required to mediate BMP-2-induced Smad signaling through a Cdc42-Src-FAK-ILK pathway.

2 We report a link between ABA and JA signaling through a direct interaction of the ABA recept

3 This gives chronic oxidative stress signaling through a feed forward loop.

4 contrast, Cap-1 modifications abrogate RIG-I signaling through a mechanism involving the H830 residue

5 ing TLR4 signaling and inflammatory cytokine signaling through a negative feedback regulation loop in

6 mice, it stimulates type I interferon (IFN) signaling through a pathway dependent on the DNA sensor

7 tory protein that counteracts FcvarepsilonRI signaling, through a pathway involving PPARg.

8 Furthermore, enhanced Shh signaling through activated Smo cannot overcome impaired

9 stimulation, the mTOR/Akt pathway amplified signaling through activating NK cell receptors by enhanc

10 ally influence HC development and that FGFR1 signaling through activation of MEKK4 is necessary for o

11 like GM-CSF or IL-5, IL-3 triggers prolonged signaling through activation of ribosomal protein S6 (RP

12 CD2AP also regulates NGF signaling through AKT, but not ERK, and regulates long-r

13 treatment also caused impairments in insulin-signaling through Akt, which were prevented by PKD1 inhi

14 Hence, ghrelin signaling through AMPK in SN dopamine neurons mediates C

15 Concurrent inhibition of Ang1 and Ang2 signaling (through an antagonistic anti-Tie2 antibody) w

16 chaperone constitutively activates receptor signaling through an abnormal interaction with the throm

17 c-Myc in a manner associated with diminished signaling through an AKT/GSK3beta/c-MYC phosphorylation

18 rombosis, the present study examined whether signaling through another switch region of G13, i.e. Gal

19 and infectious diseases and confers altered signaling through antigen receptors and PRRs.

20 egulation of gene transcription by GPCR-cAMP signaling through augmentation of the intracellular labi

21 ceptor-associated factor 3 (TRAF3) regulates signaling through B-lymphocyte receptors, including CD40

22 death promoter, thereby permitting survival signaling through BCL-XL.

23 e excitability of the BLA, and a decrease in signaling through beta2 nAChRs alters anxiety- and depre

24 These results suggest that signaling through beta2* nAChRs is essential for baselin

25 We investigated how the c-Met-mediated signaling through binding to its ligand hepatocyte growt

26 herapeutic ultrasound, indicating downstream signaling through both nitric oxide and prostaglandins.

27 r engagement, bypassed fusion, and initiated signaling through both TLR7 and TLR9, which was not util

28 Genesis of these contacts involves signaling through c-Src and Cdc42, which modulate actin

29 Taken together, these data suggest that C5a signaling through C5aR may in part play a pivotal role i

30 creatic cells is regulated by Ca(2+) and ROS signaling through Ca(2+)-induced structural changes prom

31 lly, ASIC1 is required for acidosis-mediated signaling through calcium influx.

32 erotrimeric G proteins, activates downstream signaling through cAMP and plays important roles in skel

33 ractions can reinforce each other to enhance signaling through canonical downstream second messengers

34 f M4 activators were found to require intact signaling through CB2 cannabinoid receptors.

35 We propose that CCL5 signaling through CCR5 may increase platelet counts duri

36 SNX9 assembly via its PX-BAR domain, whereas signaling through Cdc42 is activated by PI(4,5)P2 alone.

37 Antibodies have been shown to block signaling through cell surface receptors using several m

38 including therapeutic antibodies that block signaling through cell surface receptors whose ligands a

39 mechanism by which GNE activity might affect signaling through cell-surface receptors.

40 Signaling through cGMP has therapeutic potential in the

41 dicating a role for NCAM in activating EphA3 signaling through clustering.

42 e to precise regulation of beta cell mass by signaling through cognate GPCRs, and considerable eviden

43 s CRYs link the circadian clock and JAK-STAT signaling through control of STAT5B phosphorylation, whi

44 d clustering as a means to regulate receptor signaling through controlling the interactions with prot

45 miR-193b was found to regulate FAK-SRC-CRKL signaling through CRKL and FAK.

46 s positively and negatively regulated by ATM signaling through CtIP/MRN and 53BP1-bound Rif1, respect

47 Aberrant signaling through cytokine receptors and their downstrea

48 ily tyrosine kinase 2 (TYK2) participates in signaling through cytokine receptors involved in immune

49 ondrial antiviral signaling protein-mediated signaling through cytosolic pattern recognition receptor

50 Though biased signaling through D2Rs has been demonstrated, acquiring

51 ith the overactivation of G protein-mediated signaling through DA receptors.

52 hat both promote and inhibit autoimmunity by signaling through different receptors, including recepto

53 n contrast, the provision of additional ICOS signaling through direct ICOS-L expression by tumor cell

54 alpha2A-adrenergic receptor endocytosis and signaling through disrupting arrestin 3 recruitment.

55 Disruption of hepatocyte growth hormone (GH) signaling through disruption of Jak2 (JAK2L) leads to fa

56 on of murine T cells producing IL-9 (Th9) by signaling through DR3 in a cell-intrinsic manner.

57 show that CaSR and OGR1 reciprocally inhibit signaling through each other in central neurons, and tha

58 EG and prostaglandin E2 converge to activate signaling through EGFR.

59 nd we identify a novel pathway consisting of signaling through EP2/EP4-->induction of cAMP-->downregu

60 LPS receptor TLR4 and suppressed downstream signaling through ERK and NF-kappabeta, resulting in a s

61 VEGF/VEGFR2 signaling through Erk1/2 and Stat3 leads to upregulation

62 (EDCs) are suspected of altering estrogenic signaling through estrogen receptor (ER) alpha or beta (

63 by intercellular interactions involving Erk signaling through extracellular Fgf4.

64 Hh signaling through FAP cilia regulated the expression of

65 of fibroblast growth factor (FGF) 1 and FGF2 signaling through FGF receptor (FGFR) 1c.

66 Signaling through FGFR1 is also required to constrain le

67 Moreover, signaling through FGFR2, a known risk factor in breast c

68 MuSCs and demonstrate that integrin-mediated signaling through focal adhesion kinase and the p38 mito

69 of heart failure (HF), induces pathological signaling through G protein betagamma (Gbetagamma) subun

70 cell-type-specific differences in activating signaling through G protein-dependent pathways in cell-b

71 inding promotes receptor internalization and signaling through G protein-independent pathways.

72 binding events at distal sites critical for signaling through G proteins remain unclear.

73 These data are not compatible with SKF83959 signaling through Galphaq or through a D1/D2 heteromer a

74 roteins, lowers blood pressure by decreasing signaling through Galphaq.

75 ion channels (pLGICs) mediate fast chemical signaling through global allosteric transitions.

76 GluD2 receptor ligand, and endogenous D-Ser signaling through GluD2 has recently been shown to regul

77 at functions to negatively regulate cytokine signaling through GP130 and pSTAT3Y705 and is molecularl

78 ent to drive neural regeneration from MGPCs, signaling through gp130 inhibits the neurogenic potentia

79 s an important role in negatively regulating signaling through GPVI-FcRgamma and indicated that the t

80 late designer receptors that mimicked mGluR5 signaling through Gq in nNOS interneurons, we recapitula

81 se production critically depends on enhanced signaling through hepatic glucagon receptors (GCGRs).

82 in-2 (IL-2) regulates lymphocyte function by signaling through heterodimerization of the IL-2Rbeta an

83 s fully competent to support Hsp90-dependent signaling through heterologously expressed glucocorticoi

84 e of the Mst1 kinase, resulting in increased signaling through Hippo and suppressed activity of YAP a

85 Signaling through histamine receptors on dendritic cells

86 d NCoR1 and advance our understanding of how signaling through HRMs affects the major cellular proces

87 3-mediated IFN induction and downstream IFN signaling through IFN receptor was necessary to inhibit

88 ely, these data reveal that excess glutamate signaling through iGluRs induces hair-cell death indepen

89 nstrated that interleukin-1alpha (IL-1alpha) signaling through IL-1R and MyD88 in both stromal and im

90 ese phenotypic changes result from increased signaling through IL-2R.

91 tment show an additive inhibition of insulin signaling through increased IRS1 serine 307 phosphorylat

92 in CP-CML and determine if inhibition of Hh signaling, through inhibition of smoothened (SMO), was a

93 roperties that were associated with enhanced signaling through insulin and leptin receptors in animal

94 oncogenic O-GlcNAcylation regulate NF-kappaB signaling through interplay with phosphorylation and ace

95 homeostasis, group IIA/X sPLA2s inhibit Wnt signaling through intracellular activation of Yap1.

96 ncreases and promotes aberrant extrasynaptic signaling through ionotropic and metabotropic glutamate

97 To investigate the mechanism by which signaling through IRS-1 and IRS-2 results in differentia

98 ocal adhesion formation, mediates outside-in signaling through Itgbeta1 to drive cell invasion, and i

99 Insulin controls nutrient partitioning via signaling through its cognate receptor in peripheral tar

100 PMK) critically contributes to intracellular signaling through its inositol-1,4,5-trisphosphate (Ins(

101 VCAM1 affects the NSC fate by signaling through its intracellular domain to regulate b

102 NF-kappaB signaling through its NFKB1-dependent canonical and NFKB

103 Inhibitors of CSF1 signaling through its receptor, CSF1R, were tested in co

104 sosome, binds to SLC38A9 and inhibits mTORC1 signaling through its sterol transport function.

105 LGR5 potentiates WNT/beta-catenin signaling through its unique constitutive internalizatio

106 neuroprotective effects of IL-21R arose from signaling through JAK/STAT pathways and upregulation of

107 the IL-2 family of cytokines, which mediate signaling through JAK3 and various downstream pathways t

108 eptor expression, and that preventing CaMKII signaling through Kalirin and Trio prevents LTP inductio

109 mation and potentiate growth factor receptor signaling through kinase.

110 l protein to inhibit mitochondrial antiviral signaling through lipid raft-like microdomains.

111 s show that in dSPNs, endogenous cholinergic signaling through M4 muscarinic receptors (M4Rs) promote

112 Here we demonstrate that ATP signaling through macrophage P2X7 receptors uncouples th

113 oters, correlating with decreased downstream signaling through MAPK and AKT in Prox1 mutant lenses.

114 th a memory stem-cell phenotype sustained by signaling through mbIL15.

115 se and spleen tyrosine kinase activation and signaling through mechanisms that appeared largely unrel

116 clathrin-coated vesicle trafficking, defense signaling through membrane lipid metabolism and mucilage

117 expression and was not directly mediated by signaling through microglial glutamate receptors.

118 igen-mediated, B-cell antigen receptor (BCR) signaling through modulation of the function of the inhi

119 m repeat-type lectin galectin-9 (Gal-9), and signaling through mouse (m)4-1BB is reduced in galectin-

120 nd other alarmins inadvertently prime innate signaling through multiple mechanisms, resulting in the

121 The TIR-TcpC mediated inhibition of signaling through MyD88, and subsequent amelioration of

122 This mechanism links mRNA turnover to mTORC1 signaling through Nanos2-containing mRNPs and establishe

123 al and molecular manipulations that decrease signaling through neuromuscular NMDA receptors, whereas

124 show that this new function requires Sema3d signaling through Neuropilin1, which then regulates Acti

125 in pregnancy, infection, and autoimmunity by signaling through NK cell receptors (NKRs).

126 re enriched for Nod1 up-regulated cells, and signaling through Nod1 promotes competitive survival of

127 Signaling through NOD1 resulting in HCMV suppression was

128 Accordingly, signaling through Nod1 was both necessary and sufficient

129 ulates transforming growth factor (TGF)-beta signaling through Notch-mediated transcriptional repress

130 y Galphaolf subunit, and can amplify odorant signaling through odorant receptors in vitro However, th

131 ystem, we found that prostaglandin E2 (PGE2) signaling through one of its receptors, Ptger4, was suff

132 Insufficient signaling through one or more of these metabolite-sensin

133 seesaw manner, whereby conditions promoting signaling through one receptor simultaneously inhibit si

134 , sustains intramembranous bone formation by signaling through Osmr and Stat3, acting on the recruitm

135 Ablation of estrogen signaling through ovariectomy produced nipples with abno

136 In summary, Galpha12/13-mediated WNT/FZD4 signaling through p115-RHOGEF offers an intriguing and p

137 morphosis-associated transcription; finally, signaling through p38 and c-Jun N-terminal kinase (JNK)

138 Signaling through p38MAPK and JNK in reprogrammed macrop

139 This was prevented by counteracting mTORC1 signaling through p70S6Ks (S6K1/2) or eukaryotic initiat

140 Accumulating evidence suggests that signaling through PAR-1 is involved in inflammation, how

141 in and activity, diminishes thrombin-induced signaling through PAR1 to ERK, and inhibits bleomycin-in

142 r control of WNV infection, are initiated by signaling through pathogen recognition receptors, RIG-I

143 an effect mediated by specific loss of TrkB signaling through phospholipase Cgamma1 (PLCgamma1).

144 m of how O-GlcNAcylation activates NF-kappaB signaling through phosphorylation and acetylation is not

145 is report we investigate the hypothesis that signaling through phototransduction controls production

146 ressive and metastatic disease with elevated signaling through PI3K and, surprisingly, the mitogen-ac

147 strate how the interplay between biochemical signaling through positive feedback, combined with diffu

148 This study suggests that serotonin signaling through postsynaptic 5-HT1A receptors in the h

149 ride, which is believed to increase dopamine signaling through presynaptic autoreceptor blockade.

150 ride, which is believed to increase dopamine signaling through presynaptic autoreceptor blockade.

151 al pentraxin 1 from presynaptic terminals by signaling through presynaptic protein tyrosine phosphata

152 umor suppressors ZNRF3 and RNF43 inhibit Wnt signaling through promoting degradation of Wnt corecepto

153 al transforming growth factor beta (TGFbeta) signaling through protein kinase B (Akt2) induces phosph

154 Cellular signaling through protein tyrosine phosphorylation is we

155 h modulates insulin-like growth factor (IGF) signaling through proteolytic cleavage of IGF-binding pr

156 Taken together, intracellular D2LR signaling through Rabex-5/PDGFRbeta is critical for ERK

157 Signaling through RAS/MAP kinase pathway is central to b

158 e show that this impact is mediated by TORC1 signaling through reading the FAD-dependent ATP level.

159 FGF signaling through receptors Fgfr3 and Fgfr4 is crucial f

160 HCV and HIV independently activated TGFbeta1 signaling through ROS (antioxidant response elements), N

161 Slit glycoproteins signaling through Roundabout (Robo) receptors have been

162 lly validated strategy to modulate oncogenic signaling through selective attenuation of gene expressi

163 cesses - inhibiting polymerization-promoting signaling through sequestration of Rac/Rho family GTPase

164 suppressed as a result of membrane ER-alpha signaling through several kinases to inhibit carbohydrat

165 ation, and cytokine secretion in response to signaling through several TLRs.

166 anistic investigations revealed that TGFbeta signaling through SMAD2/SMAD3 was necessary for breast c

167 tiation of G protein-coupled receptor (GPCR) signaling through specific interactions with a variety o

168 Bacteria play key roles in coordinating the signaling through spleen tyrosine kinase, Src family kin

169 nvasion required matrix anchorage as well as signaling through Src, PI3K, and Rac1, and increasingly

170 s during viral infection and have convergent signaling through STAT1.

171 cells and limits inflammation by suppressing signaling through stimulatory receptors.

172 aintenance of T cells is controlled by tonic signaling through T cell antigen receptors and common ga

173 In vitro, MYD88 L265P mutation promoted p100 signaling through TAK1/IKKalpha and GSK3/Fbxw7a pathways

174 constitutive activation of type I interferon signaling through TBK1 (TANK-binding kinase), independen

175 Similarly, TLR signaling through the adaptor molecule Toll/IL-1R domain

176 Although TLR signaling through the adaptor protein, MyD88, has been s

177 Here we hypothesized that adenosine signaling through the ADORA2B on AAMs impacts the progre

178 in II-induced activation of SREBP-1 required signaling through the angiotensin II type I receptor and

179 g and shaping the initial response following signaling through the antigen receptor, inhibitory pathw

180 have previously demonstrated that DNA damage signaling through the ataxia telangiectasia mutated (ATM

181 icate that apoptin is a sensor of DNA damage signaling through the ATM-Chk2 pathway, which induces it

182 espond to antigenic stimulation by restoring signaling through the B-cell receptor (BCR).

183 These data suggest that curtailed signaling through the B7-CD28 costimulatory axis during

184 n this study, we sought to determine whether signaling through the BCAR3-Cas complex was responsible

185 e have previously reported that enhanced BMP signaling through the BMP type IA receptor (BMPR1A) in c

186 cytokines like TNFalpha cooperated with MAPK signaling through the c-Jun/AP-1 transcription factor co

187 Thrombopoietin (Thpo) signaling through the c-Mpl receptor promotes either qui

188 Signaling through the C5a-C5aR axis thus appears injurio

189 detectably alter extracellular DA levels or signaling through the cAMP/DARPP-32 signaling pathway in

190 Decreasing signaling through the cAMP/PKA pathway suppresses mutHtt

191 DA and D1R agonists, signaling through the cGMP/protein kinase G (PKG) pathwa

192 and activation of ATB2 cells was mediated by signaling through the chemokine leukotriene B4 (LTB4) an

193 C-NAP1-deficient cells were capable of signaling through the cilium, as determined by gene expr

194 during germinal center formation, and normal signaling through the classical NF-kappaB pathway.

195 This study is the first to show that BDNF signaling through the cognate tropomyosin receptor kinas

196 Mphi differentiation is mediated by signaling through the colony-stimulating factor-1 recept

197 an indirect regulator of K-Ras4A and K-Ras4B signaling through the control of PtdSer plasma membrane

198 Signaling through the DA receptor DOP-1 activates the ex

199 ed herpesvirus also did not stimulate immune signaling through the DNA-sensing pathways.

200 aled that MED1 acted directly to regulate ER signaling through the downstream IGF1 pathway but not th

201 SPASM sensors also retain signaling through the endogenous G protein milieu.

202 APPL1 degradation is blocked when signaling through the endosome is inhibited by chloroqui

203 Our studies show that forward signaling through the EphA4 tyrosine kinase receptor, me

204 CLM may attenuate signaling through the estrogen receptor by reducing leve

205 ther the presence of microbial compounds nor signaling through the extracellular ATP receptor P2X7 Mo

206 ivation with increased lysosome content, but signaling through the fractalkine receptor CX3CR1 is not

207 s followed by binding of 14-3-3 proteins and signaling through the G protein exchange factor Tiam1.

208 havioral phenotypes consistent with enhanced signaling through the G-protein coupled protease activat

209 ants underpinning GLP-1 and Ex-4 binding and signaling through the GLP-1R, these have primarily focus

210 Glucagon-like peptide-1 (GLP-1) signaling through the glucagon-like peptide 1 receptor (

211 In this article, we show that signaling through the HR inhibits ETP maturation to the

212 transgenic murine model, we demonstrate that signaling through the IFN-alpha/beta receptor is require

213 viral MOIs differentially activate JAK/STAT signaling through the IFNAR, which greatly affects the p

214 IL-13 induces CTCL cell growth in vitro and signaling through the IL-13Ralpha1.

215 Signaling through the IL-17 receptor (IL-17R) is require

216 Interleukin 2 (IL-2) signaling through the IL-2 receptor alpha chain (CD25) f

217 In contrast to IL-2, IL-15 mediated stronger signaling through the IL-2/15 receptor complex and provi

218 Here we show that interleukin 33 (IL-33) signaling through the IL-33 receptor ST2 and myeloid dif

219 IL-4 signaling through the IL-4 receptor alpha (IL-4Ralpha) c

220 Signaling through the immune checkpoint programmed cell

221 and reveal a novel role for non-canonical Hh signaling through the induction of chromosomal instabili

222 t regulates intracellular calcium levels via signaling through the inositol trisphosphate receptor.

223 s by antibiotic treatment reduced epithelial signaling through the intracellular butyrate sensor pero

224 Here, we report that novel signaling through the intracellularly localized D2R long

225 Secreted IFNs induce autocrine and paracrine signaling through the JAK-STAT pathway, leading to the t

226 Disruption of chemosensory signaling through the loss of TRMP5 abrogates the expans

227 AMLs are devoid of NRAS(V12) expression and signaling through the major oncogenic Ras effector pathw

228 such metabolic stress leads to inhibition of signaling through the mammalian Target of Rapamycin Comp

229 urokinase plasminogen activator (uPA) drives signaling through the MAPK pathway, which results in sup

230 s on Ube3A deficiency-induced alterations in signaling through the mechanistic target of rapamycin (m

231 We now show that signaling through the Mer proto-oncogene tyrosine kinase

232 osclerosis-associated foam cell formation by signaling through the miR-155-CARHSP1-TNF-alpha pathway.

233 es increased cancer cell growth and enhanced signaling through the mTOR/S6K pathway; evaluation of mu

234 tiates G protein-mediated signaling but also signaling through the multifunctional adapter protein be

235 Strikingly, dysregulated signaling through the Notch-1 receptor, recently linked

236 bitors of ATF6alpha signaling, not affecting signaling through the other branches of the UPR, or prot

237 through one receptor simultaneously inhibit signaling through the other receptor, potentiating the d

238 zed heterogeneity in PanNET characterized by signaling through the PDGF-DD/PDGFRbeta axis.

239 one marrow in a manner that was dependent on signaling through the PGI2 receptor IP.

240 AktPH domain, a translocation biosensor for signaling through the phosphoinositide 3-kinase pathway,

241 gainst ischemic and toxic cellular injury by signaling through the PI3K-AKT and MAPK pathways.

242 utations in SHORT syndrome result in reduced signaling through the PI3K-AKT-mTOR pathway.

243 uptake may be the key factor in mediating Pi signaling through the PiT proteins.

244 ival factor after ischemic and toxic injury, signaling through the plasma calcium channel PMCA4b to a

245 hymocytes, and it is required for productive signaling through the preTCR, with impaired signaling vi

246 of kynurenine found in plasma inhibited IL-2 signaling through the production of reactive oxygen spec

247 CD8(+) function and signaling through the programmed cell death protein (PD)

248 We show that cAMP signaling through the protein kinase A (PKA) pathway act

249 t by upregulation of LEPR and its downstream signaling through the protein PR/SET domain 1 (PRDM1).

250 Aberrant signaling through the Raf/MEK/ERK (ERK/MAPK) pathway cau

251 ctly blocks interaction with Raf and reduces signaling through the Raf/MEK/ERK pathway.

252 C activation inhibited VEGF receptor (VEGFR) signaling through the Ras/MEK/ERK pathway.

253 ne ALDH1A2 Interestingly, classical NFkappaB signaling through the RelA transcription factor was equa

254 Signaling through the Ror2 receptor tyrosine kinase prom

255 cular chaperones and requires TORC1 activity signaling through the Sfp1 transcription factor.

256 lesterol drives mTORC1 activation and growth signaling through the SLC38A9-NPC1 complex.

257 DMP fate and development by controlling BMP signaling through the Smad-dependent pathway to drive ti

258 Signaling through the T cell receptor (TCR) controls ada

259 ts ligand PD-L1, PD-1 is thought to suppress signaling through the T cell receptor (TCR).

260 Signaling through the T-cell receptor (TCR) is critical

261 of membrane proteins required for effective signaling through the T-cell receptor.

262 Naive fetal T cells also exhibit increased signaling through the TGF-beta pathway, with these cells

263 h transgenic TCR mouse strains, had impaired signaling through the transgenic TCRs.

264 also increased significantly in response to signaling through the TUDCA-Akt axis.

265 trigger JNK activity in epithelial cells by signaling through the tumor necrosis factor (TNF) orthol

266 rs were also shown to inhibit Tyk2-dependent signaling through the Type I interferon receptor but not

267 TLR4 triggers NFkappaB signaling through the ubiquitin ligase TRAF6 (tumor necr

268 Much has been learned of the actions of PGR signaling through the use of pharmacologic inhibitors an

269 that the MITF protein was stabilized by Wnt signaling, through the novel C-terminal GSK3 phosphoryla

270 and JAK3 contribute to constitutive JAK/STAT signaling through their reciprocal regulation.

271 ata demonstrate that C3a and C5a, via direct signaling through their specific receptors, suppress IFN

272 ability of ligands to differentially affect signaling through these pathways is termed functional se

273 Because signaling through these pathways leads to Bcl-xL inducti

274 Signaling through these receptors converged on the adapt

275 Proper signaling through this complex is achieved and maintaine

276 Then we established that signaling through this receptor complex leads to activat

277 biological response permits interrogation of signaling through thousands of quantified proteins, of w

278 Signaling through TLR3 and TLR4, which lie upstream of I

279 (m229), the latter of which is incapable of signaling through TLR5.

280 In addition, signaling through Toll-like receptor (TLR) 9 of the inna

281 Here, we show that sugar signaling through TOR controls the accumulation of the b

282 mulates invasion by promoting autocrine EGFR signaling through transcriptional up-regulation of key E

283 DNA, but not cytosolic fractions, stimulated signaling through TREM2.

284 BDNF signaling through TrkB receptors differentially modulate

285 Brain-derived neurotrophic factor (BDNF) signaling through TrkB receptors plays a well establishe

286 These findings suggest that signaling through TRPV4, triggered by changes in extrace

287 Indeed, balanced IgG signaling through type I and type II Fc receptors is req

288 e levels, including local Ag stimulation and signaling through type I IFNRs, and it coincides with th

289 hat brain-derived neurotrophic factor (BDNF) signaling through tyrosine kinase B (TrkB) receptors in

290 AR expression increases after an injury, and signaling through uPAR promotes tissue remodeling.

291 ely illustrate that, by activating NF-kappaB signaling through upregulating a cellular miRNA to targe

292 esults indicate that by activating NF-kappaB signaling through upregulating a cellular miRNA to targe

293 tes leukocyte recruitment and activation via signaling through various cell surface receptors.

294 Signaling through VE-cadherin requires association and a

295 ted HGF-MET signaling and enhanced autocrine signaling through VEGF and PDGF.

296 TLR4 knockdown inhibited VEGF signaling through VEGF receptor 2 (VEGFR2), Akt, and ERK

297 endosomal pH in regulating receptor-mediated signaling through vesicular trafficking.

298 nt and enhances cell adhesion, migration and signaling through vitronectin binding and interactions w

299 echanism for intercellular regulation of Wnt signaling through VLDLR ectodomain shedding.

300 these results suggest that KIT can activate signaling through wild-type RAF proteins, thus interferi