ライフサイエンスコーパス: signature

1 idine downstream PSSs served as a processing signature.

2 re a strengthened AMOC with a global climate signature.

3 d effects on the transcriptome with an aging signature.

4 y associated with a higher radiative forcing signature.

5 -fold change were considered a CRC proteomic signature.

6 syndromes in diseases with active type I IFN signature.

7 isk or high-risk groups based on the 52-gene signature.

8 ore set of genes comprising a vertebrate IEC signature.

9 n correlates with a BRCAness gene expression signature.

10 ique protein-coding genes yielding a 17-gene signature.

11 mpact of specific conditions on the chemical signature.

12 c infections display a persistent type I IFN signature.

13 ically relevant invasion and metastasis gene signatures.

14 t alpha, beta, delta, and PP/gamma cell-type signatures.

15 ponse and ER stress response transcriptional signatures.

16 ules distinguished by unique force-extension signatures.

17 nt-specific, high-resolution gene expression signatures.

18 o unique, highly specific and sensitive DNAm signatures.

19 entrations coupled with increased delta(15)N signatures.

20 large B-cell lymphomas with similar genetic signatures.

21 effector subsets with distinctive molecular signatures.

22 e surfaces, demonstrated by specific DESI MS signatures.

23 orted SLE loci to identify shared regulatory signatures.

24 genes previously reported as ESC-like cancer signatures.

25 variation and absence of UV-derived mutation signatures.

26 cids (PLFAs) and their carbon stable isotope signatures.

27 analysis using data-defined functional gene signatures.

28 lite on its own or other published metabolic signatures.

29 cancer diagnosis based on altered metabolic signatures.

30 This indicated that COSMIC mutational signature 24, previously hypothesized to stem from aflat

31 oter methylation is strongly associated with signature 3 and, in our data set, was highly enriched in

32 a pattern of genome-wide mutations known as signature 3.

33 ablishment of T cell exhaustion, making this signature a prime target in the search for the regulator

34 al convergence in epithelial gene expression signatures across multiple public access transcriptomics

35 lected on the basis of the murine transcript signature allowed prediction of response status with an

36 Our signature also provides information on potential candida

37 Five highly represented signature amino acid residues (37A, 95K, 224N, and 242N

38 A whole-genome sequence signature analysis identified 3 amino acid changes, 16 s

39 We designed ADAGE signature analysis to perform gene set analysis using da

40 an R package and web server to provide ADAGE signature analysis to the community.

41 tient based on the expression of the 17-gene signature and a significant increasing trend in the seve

42 hma was associated with an IL-13-induced TH2 signature and IL-1 receptor-like 1 (IL1RL1) mRNA express

43 This remodeling produces a distinct gene signature and new vulnerabilities to the proapoptotic dr

44 re characterized by their unique (77) Se NMR signatures and 2) the structure of amorphous Se consists

45 in vivo Overall, we identify gene expression signatures and candidate therapeutics that could improve

46 We identified gene expression signatures and clinical data that are associated with su

47 egion-related, and disease-related molecular signatures and may be important in other human age-assoc

48 and searching spliced sequences for splicing signatures and miRNA events.

49 While NMR and IR spectroscopic signatures and structural characteristics of low-barrier

50 port on East-Asian alpha- and beta-cell gene signatures and substantiate several genes/pathways.

51 to the establishment of new gene expression signatures and thus new cell identity.

52 levels of paused Pol II, a unique chromatin signature, and are highly expressed regardless of cell t

53 g mode confinement, polarization, scattering signature, and crosstalk, which are critical to system m

54 ssociated with stem cell-like and metastasis signatures, and their depletion impairs the metastatic p

55 Gene expression signatures are commonly used as predictive biomarkers, b

56 Because these signatures are directly learned from data without superv

57 Key properties of the calcium signatures are not intuitive, exemplifying the importanc

58 Plant volatile signatures are often used as cues by herbivores to locat

59 s an example, three distinct D-versus-sigma "signatures" are calculated, corresponding to gating by d

60 We present the 97-gene signature as an accurate prognostic predictor of overall

61 rker for HRM, we observed complex melt curve signatures as compared to 16S rDNA amplicons with enhanc

62 ong and specific correlation with a mutation signature associated with BRCA1/2 mutant tumours.

63 This glomerulocapillary miRNA signature associated with HLA class I-DSA could improve

64 ocellular carcinoma (HCC) to search for gene signatures associated with chromosomal instability (CIN)

65 e expression and alternative polyadenylation signatures associated with early-onset PE (EO-PE; sympto

66 Here, we characterized signatures associated with gluten directed immune activi

67 + blood monocyte transcriptome and epigenome signatures associated with human atherosclerosis.

68 pth bear a strong topographic and hydrologic signature at landscape to global scales.

69 roducibility and comparability of microbiome signatures at a meaningful taxonomic resolution.

70 f characteristic bidirectional transcription signatures at active TSSs in GRO/PRO-seq data, and provi

71 hibited distinct bacterial communities, with signature bacterial taxa.

72 r feature set for a compound than a spectral signature based on peak positions and intensities.

73 scriptional signatures but differed in other signatures both between cell type and between activation

74 ction not only bears its intrinsic plasmonic signature but is also imprinted with the characteristics

75 ecific activation-associated transcriptional signatures but differed in other signatures both between

76 We confirm this unique FLC signature by analysis of two independent FLC cohorts (n

77 To gain insights, we developed a signature, "CA20", comprising centrosome structural gene

78 ets, such as transcriptomic and metabolomics signatures, cell populations, and cytokine levels, and i

79 meningeal cells with distinct transcriptome signatures characteristic of (1) neurogenic radial glia-

80 t egg allergy exhibit a unique innate immune signature, characterized by increased numbers of circula

81 higher oxidative metabolism, transcriptional signatures closer to those of adult ventricular tissue,

82 with different structural and spectroscopic signatures compared with its crystalline core.

83 cell migration and stromal stimulation gene signatures compared with their SOX11(-) counterparts.

84 Signature component Lgals3 encoding galectin-3 was incre

85 ment membrane, with LN-alpha5 representing a signature component specifically produced by epithelial

86 component analysis showed a serum amino acid signature composed of arginine, leucine/isoleucine, phen

87 case, Top1 generates a distinctive mutation signature composed of short deletions in tandem repeats;

88 herapy samples from 10 cases, the mutational signatures, copy number, and SNV mutational profiles ref

89 We identified immune-related signatures correlating with clinical benefit using a lea

90 e imaging (n = 829) to assess a composite AD signature cortical thickness and hippocampal volume (HVa

91 A developmental signature could be distinguished, characterized by seque

92 mmation and identify cellular sources of the signature cytokine IL-13.

93 ey (NHANES) with BTEXS and 2,5-dimethylfuran signatures derived from the smoke of machine-smoked ciga

94 library of integrated network-based cellular signatures.Despite the importance of pharmacological and

95 In validation data, the signature discriminated cases that developed metastasis

96 the microbiota composition and the metabolic signature dramatically change.

97 and the mammary stem cell regulator Id4 This signature drove clustering of breast cancer cell lines a

98 rtments precedes and defines DNA methylation signatures during differentiation and maturation of card

99 d how levels of signal and noise in movement signatures during the 1st year of life constrain early d

100 We identify six mutational signatures (E1-E6), and Signature E4 is unique in ESCC l

101 ntify six mutational signatures (E1-E6), and Signature E4 is unique in ESCC linked to alcohol intake

102 the endosomal-lysosomal network (ELN) are a signature feature of Alzheimer's disease (AD).

103 However, enhanced gluconeogenesis is also a signature feature of type 2 diabetes (T2D).

104 -1 and HS/Npt mice, to determine a molecular signature for genetic risk for high intensity, binge-lik

105 ed to design a NET-related inflammatory gene signature for human myeloid malignancies.

106 e find the emergence of a eukaryote-specific signature for interclass complexation of canonical J-pro

107 mponent of a prognostic multigene expression signature for NSCLC.

108 lator analysis) to combine a transcriptional signature for oncogenic KRAS derived from a murine isoge

109 Within the 16 miRNA signature for the normal SC niche, we found that miR-206

110 ing pocket of AHR, with identical structural signatures for AHR induction before and after activation

111 y rate</=0.05), to identify unique proteomic signatures for each disease.

112 d the use of predictive/prognostic molecular signatures for guiding treatment decisions in breast can

113 xidation and oxygen respiration as metabolic signatures for inflammation-associated dysbiosis.

114 pting) providing highly informative chemical signatures for quality assessment.

115 s and image densitometry were used to detect signatures for the hexon, penton, fiber, minor capsid, a

116 VE-1-negative, bearing a different molecular signature from blood and true lymphatic vessels.

117 o obtain single cell-type or tissue specific signatures from a mixed signal and most of them follow t

118 AFB1 mutational signatures from all four experimental systems were remar

119 sed an efficient protocol to distil multiple signatures from the same block of data, thus reducing th

120 Transcriptome signatures from these two types of CTL responses reveale

121 , we find that mature microglia rapidly lose signature gene expression after isolation, and that this

122 icant number of genes in the transcriptional signature (gene set enrichment analysis [GSEA] p < 0.01)

123 The 57 identified meta-signature genes and involved pathways, together with the

124 Assessing 15 representative signature genes in patients with multiple sclerosis, we

125 L-17 production and expressed high levels of signature genes of the TH17 pathway, RORgammat and Il17,

126 ions eventually accumulated mutations in the signature genes strongly associated with adaptation to t

127 P3 repressed the expression of the brown fat signature genes uncoupling protein (UCP)-1 and peroxisom

128 lly and biologically relevant genes and gene signatures (GSs) measured by RNA sequencing to predict t

129 es of HCL, including its specific expression signature, hairy morphology, and antiapoptotic behavior.

130 outcome of patients, although more specific signatures have refined our prognostic abilities.

131 Moreover, the miRNA signature identified in mice predicted ulcerative coliti

132 Methylation signatures identified a layer 6 excitatory neuron subtyp

133 The order of mutational signatures identified previous treatment and germline re

134 This obliquity signature implies coincidence with a minimum of the 2.4

135 The different transcriptional signatures imply an alteration in the mode of action und

136 ividual cells, we uncover a novel mutational signature in healthy aging endocrine cells.

137 gnaling maintained a trunk neural crest gene signature in melanomas.

138 A novel amino acid and metabolomics signature in mice overexpressing muscle uncoupling prote

139 miRNA genes comprising an erlotinib response signature in NSCLC.

140 nal profiling showed little evidence for IFN signature in whole blood.

141 rmined the frequency and origin of these OCT signatures in a clinical cohort of DPED eyes.

142 and heart structure, function, and molecular signatures in a muscle- and heart-specific CPT2-deficien

143 main boundaries are marked by characteristic signatures in chromatin marks and transcription factors

144 is associated with distinct transcriptional signatures in DCs in vivo, reflecting the diverse enviro

145 main (SD) optical coherence tomography (OCT) signatures in DPED and determined the frequency and orig

146 Taken together, the results reveal miRNA signatures in PA useful to identify potential biomarkers

147 km upstream of a reservoir left geochemical signatures in sediments and porewaters corresponding to

148 Signatures in the hair cell's behavior provide a means t

149 ned effective connectivity and neurochemical signatures in the pregenual anterior cingulate cortex (p

150 This result differs from cisplatin mutation signatures in XPF-deficient Caenorhabditis elegans and s

151 ssion levels of the immature-like neutrophil signature increased linearly with pregnancy, an immune s

152 Population genetic signatures indicated that this autoimmunity variant has

153 round to individual cone receptive fields, a signature inherited by downstream neurons and implicated

154 e glycoconjugates, showing that the anomeric signature is also observable in fragments derived from l

155 score reflecting genetic variability of this signature is associated with memory performance (P=0.000

156 This signature is characteristic of aliphatic organic matter

157 The co-expression signature is conserved across 31 TCGA cancers suggesting

158 For fluorene, such signature is not identified probably due to lower oscill

159 ila embryo, we find that the poised enhancer signature is specifically generated during patterning in

160 t, which includes sample-specific mutational signatures, long-range mutation rate variation, and posi

161 Lab (Immunexpress, Seattle, WA), a molecular signature measuring the relative expression levels of fo

162 ween endotype assignment and sepsis response signature membership.

163 l mutational load was associated with APOBEC-signature mutagenesis.

164 h vaccine regimens, natural killer (NK) cell signatures negatively correlated with and predicted prot

165 A specific "peripheral lymphocyte signature" observed in patients with IgG4-RD, could supp

166 demonstrate that temporal correlations are a signature of a 'multitasking' behavior of network agents

167 to offshore conditions displayed the typical signature of a late stage biofilm, suggesting that biofi

168 To test whether the neural signature of a trait similarly varies, we investigated c

169 A transcriptome signature of activated hepatic stellate cells (HSCs), th

170 des in the immunohistochemical and molecular signature of AITL have brought increased ability to diag

171 The thermodynamic signature of AmtB-GlnK in the absence of lipids indicate

172 nts from the Thar Desert probably choked the signature of an independent Saraswati-like river.

173 rconductivity and is interpreted as a direct signature of an odd frequency superconducting order.

174 We further define a gene expression signature of anergic CLL cells consisting of several NFA

175 We found that this "core" signature of asthma is shared by mild, moderate, and sev

176 erall, these results generated new molecular signature of astrocyte types in the adult CNS, providing

177 The gene signature of blood-derived TAMs, but not microglial TAMs

178 expressed in many malignancies as part of a signature of chromosome instability.

179 ith just one coupling path, which is a clear signature of constructive quantum interference.

180 ild pollinators could recognize an exclusive signature of cues unique to each environment or flower s

181 aturation of silent synapses in the NAc is a signature of drug-context association, but this maturati

182 We therefore asked whether the DNA-binding signature of ERalpha differs between endometrial tumors

183 hallmark of FSHD, and that it is as major a signature of FSHD muscle as DUX4 target gene expression.

184 A signature of genes present in mouse ILC except NK cells,

185 d from healthy volunteers, and the mycobiome signature of hypersensitive patients differed from that

186 ed phosphate was previously interpreted as a signature of kinetics of the force-generating step in th

187 st deviation from 1/f power-law scaling, the signature of LRD.

188 ugh the tissue of residence defined the core signature of macrophages, phagocytosis imprinted a disti

189 Finally, we detect the signature of nepotism in the Italian system, with a decl

190 Finding a signature of purifying selection in a gene is usually in

191 assess whether a patient-specific molecular signature of radiation sensitivity could be used to iden

192 ognition test phase, a characteristic neural signature of recognition recruited first the right-front

193 e wild allele under short day and exhibits a signature of selection.

194 The hallmark of the TDP-43 pathological signature of sporadic ALS is restricted to cortical area

195 radio light curve of GW170817 has no direct signature of the afterglow of an off-axis jet.

196 We observed the signature of the Collisionless Shock Acceleration mechan

197 entropy per particles can be considered as a signature of the Dirac materials.

198 + N) coexistence for rod-like colloids is a signature of the first-order thermodynamics nature of th

199 nce network membership) as a neurobiological signature of the MDMA experience, and relate this brain

200 A neurophysiologic signature of the melanopsin-mediated persistent constric

201 We find a neural signature of the unique hues 230 ms after stimulus onset

202 tered in injured nociceptors, and the global signature of these LCM-captured neurons differed markedl

203 Finally, we harness the impedance signature of unstimulated T cells to set a boundary sepa

204 the absence of Egr1 identifies the molecular signature of white adipocyte browning downstream of Egr1

205 This brain region also presented signatures of a hierarchical process that disentangles d

206 We identified strong signatures of adaptive evolution at multiple sites along

207 pt has been made to understand the molecular signatures of bacterial fouling.

208 tions (15-29Hz) are among the most prominent signatures of brain activity.

209 Examination of molecular signatures of breast cancer (based on complex gene expre

210 tified new molecular markers and metabolomic signatures of cardiovascular disease risk (including bra

211 In this study, we used gene signatures of CD40L stimulation derived from human immat

212 olcano Stromboli suggest that characteristic signatures of clast recycling are different in the two e

213 new opportunities for identifying molecular signatures of coordinated behaviors of cancer cells as a

214 We uncover epigenomic signatures of domestication traits during cotton evoluti

215 e, we identify two possible crystallographic signatures of geometric frustration: excess volume and c

216 Signatures of HIV gene diversification can allow precise

217 mor microenvironment in nude mice, exhibited signatures of immune evasion, increased stemness, increa

218 To enhance the optical signatures of individual viruses and increase their sign

219 alysis identified several previously unknown signatures of infection, such as induction of potassium

220 rt Study participants to identify epigenetic signatures of kidney function.

221 rd-shifting prisms to selectively affect EEG signatures of motor but not attentional processes.

222 and Dorea were identified as gut microbiota signatures of NAFL onset and NAFL-NASH progression, resp

223 To characterize in vivo signatures of pathological diagnosis in a large cohort o

224 identifying highly conserved, novel genomic signatures of potential gene regulation in Trichodesmium

225 rphism data, progress in identifying genetic signatures of recent demography has been limited.

226 mirrored in transcriptomic and histological signatures of residual cancer cells from neoadjuvant-tre

227 We found that fMRI pattern-based signatures of reward identity in lateral posterior OFC w

228 Findings point to neural signatures of risk for maintaining PTSD symptoms after t

229 Intravital FLIM revealed the metabolic signatures of S1 and S2 proximal tubules to be distinct

230 However, we did not detect any strong signatures of selection during replication in macaques.

231 Netherlands to better understand how genetic signatures of selection translate into variation in fitn

232 re, we sought to identify neurophysiological signatures of such processes in the human brain (both fe

233 The thermodynamic signatures of the EED aminopyrrolidine compounds were fo

234 Signatures of the forcing frequencies related to the pla

235 creen with patient-derived phospho-proteomic signatures of the KRas downstream pathway, and identifie

236 ight into the interpretation of the spectral signatures of the measured 2D signals.

237 ation of potassium channels exhibits classic signatures of transmembrane allostery.

238 ed in TE sequences and display the molecular signatures of transposon-derived piRNAs.

239 rrors that function as the key computational signatures of two distinct classes of RL models-namely,

240 This may be used to identify unique chemical signatures of various cells.

241 The plume contains chemical signatures of water-rock interaction between the ocean a

242 Alternatively, quantum digital signatures offer security guaranteed by the physical law

243 icroenvironment creates an immunosuppressive signature on tumor-associated macrophages (TAM), which f

244 A "molecular signature" on transport through layers with thicknesses

245 rns identifies novel biomarkers, including a signature outperforming RAS/RAF mutations in predicting

246 experimental transmission of quantum digital signatures over channel losses of up to 42.8 +/- 1.2 dB

247 A unique geochemical signature overlaps with the southeastern flows of this v

248 nfection and that type I IFN-associated gene signatures persist, even during ART.

249 Cardiolipin (CL), the signature phospholipid of mitochondrial membranes, is im

250 denocarcinomas, the presence of the 425-gene signature predicted a significantly shorter survival.

251 us nucleotide triplet code constitutes a key signature providing PIC binding specificity in the human

252 rmation gain identified a 14 gene expression signature related to the 9VF's.

253 We further detected novel cardiac chemical signatures related to the severity and ultimate outcome

254 Our results demonstrate that these signatures represent biological processes that are pertu

255 re used to construct multiple non-joint gene signatures representing the same biological state.

256 arch of RSV inhibitors, we have integrated a signature resistance mutation into a recombinant RSV vir

257 with dicot CADs and elucidates the potential signature sequence for their substrate specificity and a

258 ine residue lying within the activation loop signature sequence S-E-G.

259 r in bacterial cytokinesis, had the "tubulin signature sequence" present in all alpha-, beta-, and ga

260 Accordingly, tumor gene expression signatures specific for myeloid cell chemotaxis and home

261 lpha diversity (Shannon index) and mycobiome signature (stability selection) of both groups of IBS pa

262 ed how to ontologically model LINCS cellular signatures such as their non-tumorigenic epithelial cell

263 asures of recovery over indirect statistical signatures, such as spatial variance or autocorrelation.

264 some-rich cells (RRCs) have a transcriptomic signature suggesting expression and secretion of extrace

265 ty of Strawn and stray gas crustal noble gas signatures suggests that the Strawn is the source of str

266 anscriptomic analyses generated a Notch gene signature that included Notch pathway components, the on

267 dels of colitis, we identified a serum miRNA signature that indicated the development of colitis and

268 FOXO1 activates a stem cell molecular signature that is also present in AE preleukemia cells a

269 phages exhibit a novel transcriptional lupus signature that is conserved within the gene expression p

270 ures associated with chiral edge plasmons, a signature that robust edge channels are intrinsic to thi

271 For the identification of transcriptome signatures that can distinguish between treatment respon

272 d to evaluate the ability of cellular immune signatures that differ between active tuberculosis and L

273 t timescales will also leave similar genomic signatures that reflect paleodrainage properties.

274 Compared to published signatures, these gene markers are more robust to identi

275 ese three metabolites were combined into one signature, they classified mice based on insulin sensiti

276 nt revealed variation in the ability of each signature to cluster samples according to patient-of-ori

277 Here, we use a chromatin signature to infer MAE for genes in lymphoblastoid cell

278 ignaling in governing an embryonic cell gene signature to promote melanoma progression, thus providin

279 blood monocyte's transcriptome and epigenome signatures to find differential methylation and expressi

280 tudy, we extended our investigation on tsRNA signatures to samples collected from patients with colon

281 A method using surrogate signatures to train the ANN was validated by comparing b

282 of applications: from transient vibrational signature tracking to amplifying weak normal Raman scatt

283 DBP-FITC, but revealed a type-I IFN (IFN-I) signature unique to DCs from Nb-primed mice.

284 h Landau level (LL) at the crossing point, a signature unique to relativistic fermions.

285 This tool illuminates spectral signatures unique to various modes of cell death, such a

286 aAlO3 /SrTiO3 , exhibit quantum interference signatures up to room temperature.

287 The signature was able to discriminate between patients with

288 In addition, the 3q gene signature was associated with better response to neoadju

289 In the metastatic subpopulations, a gene signature was defined (MET-75) that predicted survival o

290 An IFN-I signature was evident in DCs responding to the helminth

291 These DNAm signatures were able to differentiate pathogenic mutatio

292 Cytokine/protein signatures were determined by ELISA, cytometric bead arr

293 Functional CREB signatures were extracted from the transcriptomes using

294 None of these signatures were observed in healthy carriers nor at the

295 Literature-based gene signatures were used to evaluate the relative impact fro

296 same tumor mass share genomic and expression signatures, whereas geographically separated, multifocal

297 that incorporates bacterial DNA methylation signatures, which are detected using single-molecule rea

298 ns carriers showed a consistent pathological signature with numerous round, hyaline, TAR DNA-binding

299 granular brain-region and cell-type specific signatures with corresponding biomarkers in GTEx data, i

300 lls, gathering insight about other molecular signatures within macrophages that might be affected by