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2 d nonstimulant medications led to clinically significant reductions of 14.93 to 24.60 absolute points
4 ed sample study demonstrated a statistically significant reduction of 40% in 24 h BC concentrations w
6 ter 2 and 12 weeks of treatment, we observed significant reductions of 51% and 72%, respectively, in
7 (0.90) in the placebo group, representing a significant reduction of 68% (difference -2.75 dB, 95% C
11 of cholesterol levels TTP(-/-) mice showed a significant reduction of acetylcholine-induced, nitric o
12 n the pH of the potato samples resulted in a significant reduction of acrylamide formation in fried p
13 eed to be genetically inactivated to cause a significant reduction of activity-evoked release at two
14 erm sustained weight loss is associated with significant reduction of AF burden and maintenance of si
15 ction of liver inflammation accompanied by a significant reduction of alanine aminotransferase levels
17 mitral valve (MV) annular geometry, we found significant reduction of anterior-posterior (-0.31 +/- 0
21 can children had a normal FEV1/FVC ratio but significant reductions of approximately 0.5 z-scores ( a
26 SP-A/SP-B(N)-treated infected mice showed significant reduction of bacterial burden, enhanced neut
27 best compound (13a) was as low as 4 nM with significant reduction of bacterial resistance to the com
30 Bland-Altman analyses revealed a clinically significant reduction of bias when results were reported
33 utation of the Su(H) binding site leads to a significant reduction of brE reporter expression in foll
34 or its downstream target Mxi1 resulted in a significant reduction of c-Myc and Id1 ( approximately 7
36 h DES was safe but was not associated with a significant reduction of cardiac events at 3-year follow
37 ctosamine in T. cruzi-infected mice led to a significant reduction of cardiac fibrosis and inflammati
38 ion of rat ventricular myocytes and led to a significant reduction of cardiac myocyte proteins (alpha
40 d the role of ccf-mtDNA in PD, identifying a significant reduction of ccf-mtDNA in PD patient cerebro
42 is of tumor-infiltrating leukocytes revealed significant reduction of CD8(+) T cells in the tumors of
46 lesterases localized to the apoplast and had significant reduction of cell wall acetylation compared
51 electrospray (ESI)-FTICR is supported by the significant reduction of chlorophyll and its related met
52 ality improvement was demonstrated by a mean significant reduction of coma -1.52 mum after 12 months
53 as GCN2 knockout (GCN2KO) macrophages had a significant reduction of cytokine gene expression after
55 ues above these thresholds could result in a significant reduction of decomposition and mineralizatio
56 n shown that a similar program resulted in a significant reduction of delirium incidence and duration
57 wly discovered protease inhibitors yielded a significant reduction of dengue and West Nile virus tite
59 the Src kinase inhibitor PP2 resulted in the significant reduction of disinhibited synaptic currents
61 PP transgenic mice treated with NIR showed a significant reduction of endogenous Abeta at CNS synapse
62 on of nonrisk allele promoter activity and a significant reduction of endogenous GUCY1A3 expression.
63 cedent hypoglycemia with placebo resulted in significant reductions of epinephrine, norepinephrine, g
64 PET/CT and whole-body SPECT/CT resulted in a significant reduction of equivocal readings compared wit
65 n both in S2 cells and in flies results in a significant reduction of Escherichia coli-induced expres
66 he intronic mutation, showed a statistically significant reduction of exon X-containing Cep290 transc
67 ent with an anti-Neo1 antibody resulted in a significant reduction of experimental hepatic ischemia a
70 trated a synergistic loss of body weight and significant reductions of fat mass, blood glucose, and l
72 D increase in water arsenic was related to a significant reduction of FEV1 (-74.4 ml, P < 0.01; and -
73 stalk with ERK1/2 in iRhom2(-/-) mEFs, and a significant reduction of FGF7/ADAM17/EGFR-stimulated mig
74 or at both 3,13-positons of chlorin exhibit significant reduction of fluorescence in polar solvents.
77 d after digestion of fortified bread and the significant reduction of free amino groups confirm the p
79 of TDP-43-induced proteinopathy, there is a significant reduction of futsch mRNA at the NMJ compared
81 sociation due to osmotic stress results in a significant reduction of Galphaq/phospholipase Cbeta-med
82 ol women, and we demonstrate a statistically significant reduction of genes in the IL-15 pathway, kno
83 nts who underwent deferoxamine therapy had a significant reduction of GLC (from 0.64 mug/g +/- 0.29 t
88 tinib and showed reduction of the CRM genes, significant reduction of graft-infiltrating cells, and e
89 deletion of both Nap1 and Chz1 resulted in a significant reduction of H2A.Z deposition at promoters a
90 that the sdg8 deletion is associated with a significant reduction of H3K36me3, preferentially toward
92 r an in vivo model of angiogenesis, showed a significant reduction of haemoglobin content (54.2%) in
93 with WT mice, mPGES-1 null mice exhibited a significant reduction of hapten-specific serum Abs in re
95 A (siRNA)-induced gene silence resulted in a significant reduction of HCV attachment to Huh-7.5 cells
96 od cells from affected individuals exhibited significant reductions of HES1 and NOTCH3 expression ref
98 gitudinal study showed that cART resulted in significant reductions of HIV-specific effector antibody
99 sing a polarized microscope, demonstrating a significant reduction of ice crystal size induced by CCH
100 nsive BP treatment was not associated with a significant reduction of ICH expansion (relative risk, 0
103 nzyme in generating these oxysterols, showed significant reduction of IL-17-producing cells, includin
105 ment and clinical response correlated with a significant reduction of IL-6 levels in the CSF as well
107 2 month follow-up, YAM was associated with a significant reduction of incident suicide attempts (odds
109 opioids by colitogenic CD4(+) T cells led to significant reduction of inflammation-associated viscera
110 tion against influenza was associated with a significant reduction of influenza-related morbidity, he
112 ors in mouse hippocampal neurons, leading to significant reduction of inhibitory synaptic transmissio
113 ed efficient treatment of wastewater so that significant reduction of initial oxygen demand of wastew
116 techniques, but both techniques resulted in significant reduction of interface fluid during the proc
117 oing glatiramer acetate therapy as well as a significant reduction of interleukin 6 production in a s
120 ion of TbIP(3)R by RNA interference caused a significant reduction of IP(3)-mediated Ca(2+) release i
121 reatment for 3 months may be associated with significant reduction of IPA without influencing mortali
122 443 to glutamate within RGCT, which led to a significant reduction of IQGAP1 affinity for CDC42 and R
123 intestine length that was associated with a significant reduction of Ki67-positive smooth muscle cel
124 educed (18)F-FLT PET reflected a modest, yet significant, reduction of Ki67 immunoreactivity, inhibit
125 evodopa challenge, 5 mg eltoprazine caused a significant reduction of L-DOPA-induced dyskinesias on a
126 bute to resistance against S. exigua through significant reduction of larval growth and attraction of
128 ssigned to omega-3 fatty acids experienced a significant reduction of left ventricular systolic volum
131 runcated version of EXP-1 resulted in both a significant reduction of liver burden and delayed blood-
132 ) carbon tetrachloride-treated mice showed a significant reduction of liver fibrosis compared to carb
134 e mosquito bite challenge, leading to a more significant reduction of liver-stage burden and even a l
136 anical stability for all three G-quartets by significant reduction of loop interactions for the top a
140 the corresponding yeast mutation result in a significant reduction of m(7)G46 methylation of specific
141 rthritis, where this biased agonist afforded significant reduction of macroscopic and histological pa
142 different capacities allowed elimination or significant reduction of manpower, labor, and time with
148 act-based spatial statistics analysis showed significant reductions of mean diffusivity within the wh
151 f hypoxia and NFkappaB signaling resulted in significant reduction of MIF promoter activity to 0.86 +
153 e severity subgroup meta-analysis revealed a significant reduction of mortality in the intermediate-
156 phenotypic correction was associated with a significant reduction of mutant Krt75 mRNA in the skin g
157 functional mitral regurgitation experienced significant reduction of MV annular dimensions, which wa
158 validate the efficacy, but it did not show a significant reduction of myocardial ischemia and angina
161 atment with bitopertin was associated with a significant reduction of negative symptoms in the 10-mg/
163 th the Ro5-3335 small molecule resulted in a significant reduction of neovascular tufts in oxygen-ind
164 of MTA biomass in the field was linked to a significant reduction of net C uptake (-13%) of the enti
168 ith a small interfering RNA (siRNA) caused a significant reduction of NMDAR-mediated ionic or synapti
170 se models, overexpression of Sox2 leads to a significant reduction of Notch1 and Notch2 transcripts,
171 extracellular domain mutations, we observed significant reduction of NOTCH1 expression, suggesting i
172 In zebrafish, knockdown of fam65b leads to significant reduction of numbers of saccular hair cells
174 that received the computerized handoff tool (significant reductions of omissions in 11 of 14 categori
176 ogous regularization of corneal shape with a significant reduction of opposite sector index by a mean
177 ant decrease of disease incidence as well as significant reduction of oropharyngeal carriage of group
179 ive organ development in males, resulting in significant reduction of oviposition periods and fecundi
181 pecific receptor with specific antibodies, a significant reduction of P-STAT3 levels and, consequentl
182 of patients with multiple sclerosis showed a significant reduction of P2RY12, a marker expressed in h
183 ates the WNT/calcium pathway associated with significant reduction of p38-MAPK (p38-mitogen-activated
184 Reformulated OxyContin was associated with a significant reduction of past-month abuse after its intr
185 ly during follow-up by 13% (P<0.001), with a significant reduction of patients presenting an ejection
187 The absence of NFL protein resulted in a significant reduction of phosphorylated and dephosphoryl
189 polyinosinic:polycytidylic acid and found a significant reduction of plaque size in NK-cell-deficien
190 ministration of intravenous LA resulted in a significant reduction of platelet reactivity compared wi
191 te-induced macrophage depletion results in a significant reduction of portal fibrosis and portal hype
194 MHCII deficiency in pDCs was associated with significant reductions of proatherogenic T cell-derived
196 rnight following with 2-min boiling led to a significant reduction of protease inhibitor activity.
197 kdown of HTT in WT co-cultures resulted in a significant reduction of PSD-95 clustering in SPNs.
199 odies prevent and reverse PH in rats through significant reduction of pulmonary arterial inflammation
201 owder diffraction and FTIR analyses showed a significant reduction of QC crystallinity upon formulati
202 Stress-CMR strategy was associated with a significant reduction of radiation exposure and cumulati
203 ocalization in the cytoplasm, thus mediating significant reduction of RAS-GTP levels and of cell clon
206 and prevents dystrophic pathology through a significant reduction of regeneration, necrosis and fibr
207 ntral striatum) showed significant or nearly significant reductions of regional binding potential in
208 Repeated administration of A-705253 caused significant reductions of relapse-like excessive alcohol
209 oss of the first intron of vWF resulted in a significant reduction of reporter gene expression in end
210 9 mix, C. lechleri essential oil displayed a significant reduction of revertants at 0.05 mg/plate, fr
211 confirmed for 12 SQ-HDM, with statistically significant reductions of rhinitis symptoms and medicati
212 elated optic neuropathy in AD by OCT, with a significant reduction of RNFL thickness (p = 0.038), mor
214 eizure outcome was estimated on the basis of significant reduction of seizure frequency at the first
215 ariant scoring problems, thus resulting in a significant reduction of sensitivity and precision.
217 increased recipient survival and resulted in significant reduction of serum transaminases, bilirubin,
219 er tonne of suspended solids treated, with a significant reduction of sludge mass (80% reduction of w
222 increase in crumb hardness at time 0 while a significant reduction of staling was observed only at 5d
224 ownstream FAK/Akt signaling concomitant with significant reduction of stromal invasion and spontaneou
226 eemed their interventions as successful with significant reduction of symptoms irrespective of AF.
228 amber pacemaker programmed to DDD60 led to a significant reduction of syncope or symptomatic events a
232 with overexpression of dFMRP resulting in a significant reduction of TDP-43 in the aggregate fractio
233 ith ongoing islet autoimmunity resulted in a significant reduction of TFH precursors in peripheral bl
234 aralogs in Nicotiana benthamiana resulted in significant reduction of TGB1 accumulation in the nucleu
235 suppressed in naive T cells, paralleled by a significant reduction of Th17 cells in the lamina propri
236 PBMCs treated with ANE for 4 hours showed a significant reduction of the adherent cells on the micro
237 The spin transition is associated with a significant reduction of the aggregate VP/VS via the agg
238 ior to 3-AP and 3-AP-Me treatment leads to a significant reduction of the antiproliferative propertie
239 iet, Gucy1a3(-/-)/Ldlr(-/-) mice exhibited a significant reduction of the atherosclerotic plaque size
241 acebo controls, this combination resulted in significant reduction of the bacterial burden in tissue
243 ding to Scheimpflug-based CATCRP result in a significant reduction of the CAant and CATCRP, but do no
244 n of myocardial FA uptake in atATGL-KO and a significant reduction of the cardiac hypertrophic respon
247 with state-of-the-art algorithms and with a significant reduction of the computational complexity.
249 e sites with an inactive mutant results in a significant reduction of the demethylation rate without
250 AMs on the electrode surface, resulting in a significant reduction of the electron transfer resistanc
252 eduction of its 5,6-double bond results in a significant reduction of the exchange rate (k(ex)) betwe
253 human kallikrein 5 transgenic mouse revealed significant reduction of the global proteolytic activity
254 ia additional ethenylene linker results in a significant reduction of the HOMO-LUMO gap and an enhanc
255 rug resistance that can be associated with a significant reduction of the intracellular platinum conc
257 e O1 antigen of C. turicensis cells caused a significant reduction of the membrane potential which is
259 The placebo group, in contrast, displayed a significant reduction of the N400 repetition effect afte
260 LOD) of 10 ng/mL (400 pM), attributed to the significant reduction of the net charge of JR2EC upon di
266 C activity by bile acids is accompanied by a significant reduction of the single-channel current ampl
267 Such arrangement is accompanied by a very significant reduction of the source temperature, in prin
270 e and can achieve favourable outcomes with a significant reduction of the treatment burden compared t
272 use models, 4LB5 administration results in a significant reduction of the tumor volume without eviden
273 We attribute the improved emission to a significant reduction of the work function rather than a
277 ardiac output optimization protocol led to a significant reduction of total isovolumic time with conc
282 ministration of VSV-DeltaM51-GFP resulted in significant reduction of tumor growth for tested mouse P
283 armacokinetic properties, and demonstrates a significant reduction of tumor growth in vivo on A375 xe
284 commercially processed and prepared foods, a significant reduction of US sodium intake could occur.
285 n affected-female-derived fibroblasts showed significant reduction of USP9X level, confirming the los
286 ubglottic secretion suctioning resulted in a significant reduction of ventilator-associated pneumonia
292 treatment of cells with AS1411 results in a significant reduction of viral titers after DENV infecti
294 oximal external region peptides) resulted in significant reduction of virus neutralization, suggestin
295 suggested that nhx5 nhx6 knockouts showed a significant reduction of VSR binding to both cargoes.
296 s with VT recurrence, CA still resulted in a significant reduction of VT burden, with 31 (53%) patien
297 tients with VT recurrences, CA resulted in a significant reduction of VT burden, with 8 (50%) having
298 nificantly reduced in both groups, whereas a significant reduction of WAR and mixed (gas + liquid) re
299 s with IP linTT1-D(KLAKLAK)2-NWs resulted in significant reduction of weight of peritoneal tumors and
300 With this small sample size, we observed significant reduction of white blood cell and absolute l
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