ライフサイエンスコーパス: significantly alter

1 tein ions, their conformational profiles are significantly altered.

2 e single and double lambda3r mutants was not significantly altered.

3 ermal growth factor receptor levels were not significantly altered.

4 based on this technique, blood flow was not significantly altered 30min after treatment.

5 MPA significantly altered 35 proteins mainly related to nucl

6 133 S-stamped vs 3/32 unstamped) and did not significantly alter 6-month endothelial cell loss (31+/-

7 The same peptides significantly altered a nicotinic receptor induced behav

8 Additionally, CPAP treatment significantly altered a total of 47 plasma miRNAs and de

9 2775 unique proteins, of which 316 exhibited significantly altered abundance during LS diet.

10 y established roles in pathophysiology, have significantly altered activity in corresponding diseases

11 Spectral fingerprints of A. baylyi significantly altered after 1-h exposure to pure alkanes

12 ncentrations of luteinising hormone were not significantly altered after 5 days of NKB antagonist (me

13 e found circulating expression profiling was significantly altered after CRT.

14 pair capacity in U2OS cells were found to be significantly altered after TUFM knock-down.

15 we demonstrated how different approaches can significantly alter analysis outcomes.

16 expressions of E-cadherin and alpha-SMA were significantly altered, and these alterations were signif

17 e generation of viable chimeric viruses with significantly altered antigenicity and virulence.

18 choactive or cardiovascular effects, did not significantly alter any of these outcomes.

19 rescue, synapse formation in these fish was significantly altered as a result of delayed AChR expres

20 ese surface properties and performances were significantly altered as CBLG bound to serum proteins.

21 and showed that aberrant DNA methylation is significantly altered at enhancer regions and that the m

22 ed States, cities' hard infrastructures have significantly altered at least 7% of streams, which infl

23 hronic exposure to a neonicotinoid alone can significantly alter bee flight.

24 , and membrane stability were observed to be significantly altered between EAE and control (p < 0.05,

25 ized in beta1-integrin(RNAi) animals without significantly altered body-wide patterning.

26 brain after administration of (64)Cu-GTSM is significantly altered by AD-like pathology in the TASTPM

27 response kinetics of distal inputs were not significantly altered by dendritic filtering.

28 ntified, among which 144 proteins were found significantly altered by diabetes.

29 ctivation in intestinal epithelial cells are significantly altered by germ-free conditions.

30 The amplitude modulation was not significantly altered by head-on-trunk position, but the

31 that average metabolite concentrations were significantly altered by increased body mass (90 of 130)

32 ions) of a flexible fluorescent probe can be significantly altered by its embedding micro-environment

33 ve and neurogenic effects on NSCs, which are significantly altered by microglial miR-155 overexpressi

34 rg(-/-) slices, both forms of plasticity are significantly altered by P42.

35 the interactions between the HK domains are significantly altered by photoconversion.

36 erum amyloid A, and lipid peroxidation, were significantly altered by polybacterial infection, demons

37 , 69.27, p = 0.969; Q = 0.69, I(2) = 0%) was significantly altered by statin therapy.

38 six sites on TSC2 whose phosphorylation was significantly altered by the EC treatment.

39 indicates that the dimensions of PEG are not significantly altered by the presence of either guanidin

40 c effects of individual mutations were often significantly altered by the presence or absence of othe

41 cterize the cell subsets identified as being significantly altered by trauma using cytometry by time-

42 o be interpreted with caution since they are significantly altered by variables like fasting and medi

43 y composition and structure were subtly, but significantly, altered by fertilization, with higher alp

44 whether pathophysiologic changes in pHo can significantly alter CaR responsiveness in both heterolog

45 nses during a simultaneous coinfection would significantly alter CD8 T cell memory in a mouse model w

46 iting DC migration out of the liver does not significantly alter CD8(+) T cell responsiveness, indica

47 rchitecture of the lung microenvironment can significantly alter cell function and injury and demonst

48 Modulation of miR-143 in PASMCs significantly altered cell migration and apoptosis.

49 ypoxia-affected cells undergo sickling which significantly alters cell dynamics.

50 ly rare cells while cell culture methods may significantly alter cellular phenotypes and gene express

51 Untargeted metabolomics further revealed a significantly altered cellular content of 58 metabolites

52 NAFLD is associated with significantly altered circulating BA composition, likely

53 in (0.32 mg/kg per day) doses also failed to significantly alter cocaine choice.

54 aily sulindac administration in FAP patients significantly altered colorectal stem cell dynamics, whi

55 ming effect of fluctuating resources did not significantly alter community temporal variability.

56 ting reduces junctional current, it does not significantly alter conduction velocity during cardiac f

57 nalysis revealed that individual nucleosomes significantly alter CPD formation, protecting nucleosoma

58 ounterparts, both macrophages and SCs showed significantly altered cytokine gene expression in neurof

59 Modulation of ZIP6 and ZIP7 expression significantly altered cytosolic zinc influx in pancreati

60 As we previously reported, hypoxia significantly altered dendritic cells (DCs) to a DC2 phe

61 prefrontal cortex of the fmr1(-/y) mouse is significantly altered due to changes in several voltage-

62 observe that the crystallization kinetics is significantly altered due to the formation of these inte

63 , miR-195-5p, miR-223-3p, and miR-451a) were significantly altered during the 48 hours interval.

64 The Three Gorges Dam has significantly altered ecological and environmental condi

65 activation of the M3 RASSL receptor did not significantly alter either M3-M3 homomer or M2-M3 hetero

66 lifoliae in the treatment plots, but did not significantly alter either the species richness or abund

67 hat the occurrence of SNPs within three COMs significantly altered enhancer activity.

68 disrupts MLL2/4 and SETd1B complexes without significantly altering enzymatic activity in vitro Notab

69 Finally, perilipin1 knockdown significantly altered ethanol-induced lipophagy.

70 As the structure is significantly altered, even at low hydration levels, rep

71 ion in patients with NASH and 177 genes with significantly altered expression in patients with NAFLD,

72 Of the 65 genes with significantly altered expression in patients with NASH a

73 identified four splicing factors exhibiting significantly altered expression levels in HD patient br

74 RNA-seq analysis identified significantly altered expression of 62 transcripts share

75 r-depleted monocyte/macrophage cells display significantly altered expression of cell-surface markers

76 Many common TE variants were associated with significantly altered expression of nearby genes, and a

77 We identified 19 genes with significantly altered expression, including many known t

78 e in charge state upon supercharging without significantly altering folding in solution.

79 und vegetation as cover and flowering is not significantly altered for most species.

80 etics, and biodistribution patterns that are significantly altered from monomeric HP-beta-CD.

81 lication rate, and protein synthesis are not significantly altered from those of the normal rod-shape

82 performed before fructose ingestion does not significantly alter fructose oxidation and storage.

83 HD mice exhibited significantly altered functional connectivity in multipl

84 Shaker-iVSD showed significantly altered gating kinetics and formed a catio

85 CsA use significantly alters GCF and plasma levels of TGM-2 and

86 results suggest that PenStrep treatment can significantly alter gene expression and regulation in a

87 how that historical introgression of tyr (a) significantly altered genomic composition of the laborat

88 es of membrane oxygenators and pumps did not significantly alter hemostasis.

89 in corticosterone plasma levels, but did not significantly alter HPA-axis activity of non-stressed co

90 Antiprotease antibodies did not significantly alter IgA1P activity.

91 lysis revealed that the experimental regimen significantly altered immune reactivation and DNA repair

92 NP aggregation will significantly alter in vitro behavior (dosimetry, NP upt

93 tor potential channel C6 in the podocyte was significantly altered in 1,25-vitamin D3-deficient anima

94 ies of the intrinsic carbonyl compounds were significantly altered in 40% ethanol solutions using two

95 wo diglycerides and two acyl-carnitines were significantly altered in AAI treated rats at week 4 when

96 , HLA-DRA and IPMK transcript expression was significantly altered in AD brains compared with control

97 eptin concentrations in saliva and serum are significantly altered in CP and relate closely to curren

98 okinetics of bufuralol and debrisoquine were significantly altered in CYP2D6-HBN mice, the AUC0-8 h b

99 regions of C. jejuni FlhG that are absent or significantly altered in FlhG orthologs are involved in

100 pecific nucleolar proteins whose levels were significantly altered in H1DeltaTKO mESC.

101 k index, pH, lactate, and base deficit) were significantly altered in hypotensive patients.

102 FXR signaling in the liver and intestine was significantly altered in mice with NAFLD as well as in t

103 of BR biosynthesis genes and SAUR genes are significantly altered in mtbri1 mutants.

104 In conclusion, microRNA biogenesis, significantly altered in neutrophils of APS and SLE pati

105 Of these, 395 proteins were significantly altered in obesity before surgery, and 280

106 pproximately 2% of all analyzed sncRNAs were significantly altered in OIR retinas compared with normo

107 he expression of hnRNP A1/A2 and PTB/nPTB is significantly altered in patients with frontotemporal de

108 RA deformation properties are significantly altered in pediatric PH patients.

109 ctivity of stream-dwelling organisms will be significantly altered in response to future climate chan

110 assessed in permeabilized myofibers were not significantly altered in response to mitoquinone mesylat

111 LOXL1-AS1 expression is also significantly altered in response to oxidative stress in

112 re associated with protein aggregation, were significantly altered in SH-SY5Y cells treated with MNPs

113 jasmonic acid (JA) biosynthesis pathway was significantly altered in the course of elevated CO2 trea

114 temic redox balance of cataract patients was significantly altered in the course of glaucoma.

115 phingolipids, and other membrane lipids were significantly altered in the ctl1 mutant, linking CTL1 f

116 position, structure and functional potential significantly altered in the degraded soils with bacteri

117 auxin and salicylic acid) response genes are significantly altered in the F1 hybrids relative to the

118 The abundance of these smRNAs is significantly altered in the leafbladeless1 mutant, sugg

119 osynthetic genes for auxin and cytokinin are significantly altered in the Osarid3 mutant calli.

120 e, ecological and evolutionary dynamics were significantly altered in the three-species system compar

121 t the TET2 expression and 5hmC abundance are significantly altered in the umbilical veins of GDM and

122 hemokines, and co-stimulatory molecules, was significantly altered in tumour-induced DCs compared to

123 e within the first EF-hand domain of PLCzeta significantly alters in vivo Ca(2+) oscillation inducing

124 pated metabolites were also determined to be significantly altered including Krebs cycle intermediate

125 hat genes in the ubiquitination pathway were significantly altered, including: BRCA1, TSPYL5 and PEX1

126 IL-17, alone or synergistically with TNF, significantly alters inflammatory gene expression in cul

127 ack of Cx3cr1 expression was associated with significantly altered intestinal microbiota composition,

128 etragonal phase transition in perovskite can significantly alter its optical, electrical properties a

129 tion-dependent lead in the LFP phase without significantly altering its amplitude.

130 creased the membrane expression of Kv7.4 and significantly altered Kv7.4 current properties.

131 for energy and water balance, but also have significantly altered land-atmosphere CH4 emissions for

132 rk and lipid bilayer of diseased RBCs may be significantly altered, leading to impaired functionality

133 hree iTRAQ experiments and 104 proteins with significantly altered levels (protein ratio >/=1.5 or </

134 duced lamellar bodies in granular layers and significantly altered lipid composition.

135 rventions decreased plasma apoE, but neither significantly altered lipoprotein lipase and cholesteryl

136 ty mass spectrometry (UPLC-QTOF/HSMS) showed significantly altered lysoPC(18:1), PE(18:3/16:0), PC(20

137 are major epigenetic modifications known to significantly alter mammalian gene expression.

138 rrent emissions trajectory would rapidly and significantly alter many ecosystems and the associated s

139 These changes are likely to significantly alter mass flowering and fruiting events i

140 allographic defects such as dislocations can significantly alter material properties and functionalit

141 Crystallographic imperfections significantly alter material properties and their respon

142 tworks indicated down regulation of 14 genes significantly altered metformin sensitivity in two breas

143 ryos of stressed Slc6a4 (+/+) dams exhibited significantly altered methylation profiles and different

144 onged exposure of naive wild-type mice to EE significantly altered microglial density and branching c

145 localised glial reactivity in these mice and significantly altered microglial morphology.

146 mbination of both generate exosomes carrying significantly altered microRNA profiles compared to non-

147 (70%) activities, decreased ATP levels, and significantly altered mitochondrial structure.

148 Moreover, C-terminal fragments exhibited significantly altered mobility in denatured immunoblots

149 te of PF/PL/A, and readmission rates did not significantly alter model outcomes.

150 These findings support a significantly altered model for endocytic recycling in m

151 resistance-associated genetic configurations significantly altered molecular interactions underlying

152 Results showed that LPS treatment significantly altered mRNA levels from 2563 genes.

153 d changes in expression of seven of the most significantly altered mRNAs.

154 This was associated with significantly altered mTOR, but not Akt or HIF-1alpha, a

155 quencing and LC-MS/MS comparisons pointed to significantly altered MYC-signaling.

156 ological analysis of mature neurons revealed significantly altered neurite length and soma size in CS

157 while permissive to the recognition of CD1d, significantly altered NKT cell development, which result

158 blockade eliminated NOTCH-BCR activation and significantly altered NOTCH downstream targets and B-cel

159 turbation of synaptic input to granule cells significantly alters olfactory-guided behavior.

160 tree genera in the upper Midwestern US have significantly altered over the last two centuries due to

161 serum levels of 96 proteins were found to be significantly altered (P < 0.001, q < 0.01) in mdx mice.

162 k demonstrates that hydrodynamic effects can significantly alter particle deposition relative to expe

163 Significantly altered pathways identified through bioinf

164 to ERAP1 trimming and together resulted in a significantly altered peptidome with lower affinity.

165 In addition, mutagenesis of a significantly altered phosphorylation site on xCT (SLC7A

166 deliberate manipulations of their expression significantly alter plant susceptibility to H. schachtii

167 from robbers [2], provided that they do not significantly alter pollinator visitation to the detrime

168 We found that spike rate was significantly altered prior to seizure in 9 out of 15 su

169 Although it was not predicted to significantly alter protein folding stability, it is pos

170 ucture of the wild-type (WT) channel but has significantly altered protonation and tautomeric equilib

171 ssing cells using RNA-seq reveals that Ptf1a significantly alters pyramidal cell gene expression, upr

172 camera without compromising image quality or significantly altering quantification of myocardial perf

173 The LAI variations significantly alter radiation regime, within-canopy micr

174 nists by decreasing receptor reserve without significantly altering receptor function.

175 ine substitutions at this critical interface significantly altered RopB-dependent speB expression and

176 We identified trajectories which significantly altered sepsis mortality, and found three

177 genes, which may be used to further filter a significantly altered set of genes identified through wh

178 we show that elevated GDC L-protein activity significantly alters several diagnostic parameters of ce

179 irect evidence that the striatum contributes significantly altered signals to the network in patients

180 monstrate that conserved UBA motif mutations significantly alter SNF1 kinase activation and biologica

181 cover a new defining feature of IDS: mothers significantly alter statistical properties of vocal timb

182 increases the NALP3 protein lifespan without significantly altering steady-state mRNA in human cells.

183 ely activates the innate immune response nor significantly alters steady-state granulopoiesis.

184 hat subclinical levels of plasma LPS in vivo significantly alter T cell proliferative capacity, monoc

185 I lung adenocarcinoma lesions already harbor significantly altered T cell and NK cell compartments.

186 We found that active MEK significantly alters TDP-43-regulated splicing and that

187 Thus, a single amino acid substitution can significantly alter the AAV capsid integrity to the exte

188 ents showed that polymer conjugation did not significantly alter the Ab's binding affinity or kinetic

189 t the attachment of ACT to a ligand does not significantly alter the binding affinity and specificity

190 ultralow levels of residual antibiotics may significantly alter the biogeochemical cycle of nitrogen

191 genes involved in immune responses failed to significantly alter the C. muridarum induction of uterin

192 ein with the double bromodomains of BRD4 may significantly alter the cellular gene expression profile

193 ion to interact with the atmosphere does not significantly alter the characteristics of the AMO in th

194 t the oligonucleotide tertiary structure can significantly alter the chemical composition of the SNA

195 iting in microRNAs, particularly in seed can significantly alter the choice of their target genes.

196 ions, but including spatial contrast did not significantly alter the circadian phase resetting effici

197 delineation of fetal anomalies, it does not significantly alter the course of the pregnancy or the m

198 If successful, this program may significantly alter the current paradigm of AHF patient

199 ear optical process is shown to actively and significantly alter the density excitation response of a

200 lex suggests that the three mutations do not significantly alter the drug-enzyme interactions.

201 n, and this so called "priming effect" might significantly alter the ecosystem C balance.

202 e and oxygen content in the microenvironment significantly alter the efficacy of human CPC-derived ex

203 t kinetics, and not just thermodynamics, can significantly alter the efficiency of self-assembly in a

204 n of PIKfyve in glomerular podocytes did not significantly alter the endosomal morphology, even in ag

205 it is shown that the surrounding solvent can significantly alter the energetic as well as the entropi

206 The KCNE ancillary subunits (KCNE1-5) significantly alter the expression and function of volta

207 onstrate that ingestion of microplastics can significantly alter the feeding capacity of the pelagic

208 he same loop (179, 180, and 182-184) did not significantly alter the functional up-regulation of CaV1

209 ssociated with environmental alterations can significantly alter the impact of these factors in the d

210 The nanodiamond co-deposition can significantly alter the lithium plating behavior, afford

211 prognostic tools that have the potential to significantly alter the management of CVD.

212 s revealed that metabolic resistance did not significantly alter the mating competitiveness of male A

213 rt that manipulations of gonadal hormones do significantly alter the maturation of inhibitory neurotr

214 Nanoscale carbon-based fillers are known to significantly alter the mechanical and electrical proper

215 The use of aSWNTs alone did not significantly alter the mesolimbic dopamine system, wher

216 ; however, leader and trailer lengths do not significantly alter the observed rate constants of PRORP

217 s prove that changes in expression level may significantly alter the organization and mobility of int

218 Although loss of Epb41l5 does not significantly alter the pattern of neural progenitor cel

219 result from underlying genetic variants that significantly alter the phenotype of vascular smooth mus

220 Interestingly, treatment with BBR did not significantly alter the phosphorylation state of AMPK in

221 that overexpression of LIN28B or let-7g can significantly alter the postnatal production of HCs in r

222 ate how changes in vaccine regimen alone can significantly alter the quality of antibody responses to

223 dition of lixisenatide to usual care did not significantly alter the rate of major cardiovascular eve

224 strated that PARP inhibitor olaparib did not significantly alter the rate of PARP1 dissociation from

225 Tight glycemic control did not significantly alter the response profile.

226 e that that direct-write e-beam exposure can significantly alter the rigidity of elastomeric poly(dim

227 was overestimated by >2 points, which could significantly alter the risk profile of hospitals treati

228 innovations culturally, unfamiliar habitats significantly alter the route and pace of human dispersa

229 tingly, these modifications are predicted to significantly alter the secondary structure of the large

230 With time, growing roots significantly alter the soil physical environment in the

231 applied magnetic fields of moderate strength significantly alter the spin arrangement within the syst

232 Local changes in pH are known to significantly alter the state and activity of proteins a

233 en two dissimilar materials can abruptly and significantly alter the surrounding electric potential,

234 s reveal that the packing of the protein can significantly alter the thermodynamics and kinetics of l

235 stressed growth condition, mutation of lrgAB significantly altered the abundance of 76 proteins (a fo

236 ivalinal affected arterial blood pressure or significantly altered the amyloid pathology in APP mice.

237 ions, including ICDs for SD prevention, have significantly altered the clinical course, now resulting

238 Whether such management advances have significantly altered the considerable mortality rate fo

239 S volume/proportion of minority patients all significantly altered the effect-combined accounting for

240 Tainting participants with unnoticed odors significantly altered the effects, thus verifying their

241 st stressed when associating with hosts that significantly altered the expression of 184 genes under

242 ed that tetracycline-mediated AREG silencing significantly altered the expression of 2331 genes, 623

243 In addition, the SFA diet significantly altered the expression of 28 transcripts [

244 Overexpression of PsnSHN2 in tobacco significantly altered the expression of both transcripti

245 (OE) of TSPAN5 in a neuroblastoma cell line significantly altered the expression of serotonin pathwa

246 Mechanistically, covR mutation significantly altered the expression of several genes in

247 Overall, we show that rising [CO2] significantly altered the functioning of mycorrhizal ass

248 HMGB1 depletion in XPA-deficient human cells significantly altered the ICL-induced mutation spectrum

249 The presence of dispersant significantly altered the microbial community compositio

250 ale association with carbonate minerals have significantly altered the molecular signatures of Gunfli

251 We found that effluent addition significantly altered the physicochemical properties of

252 We found that the genotype with root hairs significantly altered the porosity and connectivity of t

253 nockdown in nCPCs or overexpression in aCPCs significantly altered the quality of their secretome.

254 Colitis significantly altered the stability of mucosal RGE.

255 Use of PET/CT significantly altered the stratification of tumor stage

256 eased epithelial cell height at 18 days, and significantly altered the temporal pattern of plasma FT4

257 ions to modulate aquaporin activity, thereby significantly altering the plant hydraulic parameters in

258 emman (FXYD1) inhibits pump function without significantly altering the pump's voltage dependence.

259 le surface, the hydrophilicity is decreased, significantly altering the retention and selectivity obs

260 hylation of the Sm spliceosomal proteins and significantly altering the spliced repertoire of RNAs in

261 broad effects on the transcriptome of Pf-5, significantly altering the transcription of more than tw

262 NaV channels, Tp1a inhibited hNaV1.7 without significantly altering the voltage dependence of activat

263 We show that treatment for CIN significantly alters the biochemistry of the cervix, com

264 e resonant nature of the nanophotonic system significantly alters the design criteria for the necessa

265 We revealed that DC3000 significantly alters the expression levels of 71% effect

266 Importantly, loss of Gcn5 significantly alters the genomic distribution of NER rat

267 These data indicate that PalC significantly alters the host response in the MLNs, acti

268 to demonstrate that trace fear conditioning significantly alters the intrinsic excitability of mPFC-

269 FR171456 significantly alters the levels of cholesterol pathway i

270 that ex vivo anisotropic mechanical stretch significantly alters the miRNA expression profile in dia

271 Changing the functional groups on the anion significantly alters the open circuit voltage and yields

272 show that the topography of the environment significantly alters the optimal search strategy toward

273 Polystyrene grafting significantly alters the physical and chemical propertie

274 e countercation in the borate salt (MB(OH)4) significantly alters the physical properties of the hydr

275 Phospholipid scrambling significantly alters the physical properties of the memb

276 roduces transient reactive intermediates and significantly alters the reactivity of a chemical compou

277 Significantly, altering the block copolymer hydrophilic-

278 e, resulting in their functionalization, may significantly alter their toxicity.

279 o individuals' psychological characteristics significantly altered their behavior as measured by clic

280 tion of ASICs within muscle afferents, which significantly altered their pH sensing characteristics.

281 g parameters for thin film materials without significantly altering their physical properties.

282 -nerve interactions at sites of inflammation significantly alter tissue innervation.

283 ipt analyses revealed that the liaS mutation significantly altered transcription of the genes encodin

284 s (1) the dynamic features of signaling that significantly alter transcriptional regulatory patterns

285 and ZBTB16 as candidate CHD genes because of significantly altered transcriptional expression.

286 More generally, we find a significantly altered transcriptome in the slow-growing

287 Transcriptional profiling identified significantly altered transcripts in response to RAB25 e

288 d had ribosome footprints, including 56 with significantly altered translation under Pi-limited nutri

289 that the expression levels of 29 genes were significantly altered upon isoprene SOA exposure under n

290 The ps-ns motions were not significantly altered upon substrate binding.

291 coxsackievirus B3 polymerase mutations that significantly altered virus replication rates and in viv

292 sociated with each ChA molecule or salt that significantly altered wettability compared with controls

293 l of cell-specific downstream targets can be significantly altered when the controlling factor is mut

294 Methamphetamine choice was not significantly altered when the FR response requirements

295 olved in cell energy metabolism pathways was significantly altered, which were further validated with

296 both community richness and composition were significantly altered while in the moist tundra, only co

297 sults demonstrated that the BA profiles were significantly altered with ANIT intervention and YCHT po

298 ehind the binding of these modulators can be significantly altered with only minor substitutions to t

299 c blocked swimming motility but also did not significantly alter Xoo/Xoc virulence.

300 d at positions 365, 368, and 373 exhibited a significantly altered ZO-1 interaction profile, while mu