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1 nt lines with mutations within this motif is significantly reduced.
2 onents (p22phox, p67phox, and gp91phox) were significantly reduced.
3 osis or when hydrogen peroxide biogenesis is significantly reduced.
4 the severity of AAA in the CAR-DCN group was significantly reduced.
5 still present, but TA and D populations were significantly reduced.
6 mice, whereas in tolerized mice levels were significantly reduced.
7 peat (LTR) from Vpr-deficient proviruses was significantly reduced.
8 C/DA ratio but interindividual variation was significantly reduced.
9 egulatory cells were present in DKO mice but significantly reduced.
10 current responses to exogenous glycine were significantly reduced.
11 l cIMT (a prespecified tertiary outcome) was significantly reduced (-0.013 mm per year, -0.024 to -0.
13 d, deaths after breast cancer (n = 134) were significantly reduced (40 deaths [0.025% per year] v 94
15 t pathway using TNT003 or C1q-depleted serum significantly reduced adhesion of monocytes in the prese
16 scle cells (HASMCs) with synthetic phenotype significantly reduced adiponectin accumulation on HASMCs
17 of Pep19 into diet-induced obese Wistar rats significantly reduces adiposity index, whole body weight
23 y ill patients, extended-duration betrixaban significantly reduced all-cause stroke and ischemic stro
24 absence of linker contacts, H-NS binding is significantly reduced, although no change in chromosome
27 ns, the density of microglia/macrophages was significantly reduced and microglia in part converted to
28 obese (DIO) rats, the apoA-IV mRNA level is significantly reduced and that the estrogenic effects on
29 ld type (wt) mice treated with NIR light was significantly reduced and the resulting suppression of l
30 of the CDC20-MAD2 complex are gradually, but significantly, reduced and this is associated with lower
31 and CD8(+) memory T-cell differentiation was significantly reduced, and T cells did not express CXCR3
34 ma cell line (N2A), we also found that NLRX1 significantly reduced apoptosis under hypoxic conditions
37 s fed with 1,3-DAG-rich oil were found to be significantly reduced as compared to rats fed diet conta
38 a monoclonal antibody that has been shown to significantly reduce asthma exacerbations and improve lu
39 erograde intraflagellar transport (IFT), was significantly reduced at (tam)Arl13b(-/-) basal bodies,
40 genes for glycoproteins gC, gE, and gI, was significantly reduced at 36 h postinfection for the hype
41 chronic B cell depletion (Baffr deficiency) significantly reduces atherosclerosis in Apoe (-/-) mice
42 in increased open state stability and hence significantly reduced ATP sensitivity and a marked incre
45 mprovement over previous Tet-On systems with significantly reduced background expression and increase
46 i-Conjugation is manifested in these COFs in significantly reduced band gap (1.8-2.2 eV), solid state
48 , administration of ruxolitinib for one week significantly reduced biomarkers of inflammation and fib
49 enting stroke or systemic embolic events and significantly reduced bleeding and cardiovascular mortal
51 We found that the 5-HT2CR agonist lorcaserin significantly reduced both ad libitum chow intake and PR
52 r non-peptidergic nerve fibers, was not only significantly reduced but could also be correlated with
53 ol to suppress RNS, not only are DNA lesions significantly reduced, but also the onset of pancreatic
54 epithelium and IL-13 in the mesenchyme were significantly reduced, but Tm burden was not affected.
56 ricular arrhythmia score during exercise was significantly reduced by flecainide (0 [range, 0-2] vs 2
59 rolysed starch during in vitro digestion was significantly reduced by sourdough fermentation with a p
60 joint, but not myeloperoxidase activity was significantly reduced by SzV-1287 in K/BxN-arthritis.
62 sphatidylinositol 3-monophosphate (PI3P) was significantly reduced by Vps34 deletion, resulting in en
64 rison to a variety of different controls and significantly reduced cardiac pathology in a BALB/c mous
68 lencing of XPO1 by either shRNA or selinexor significantly reduced cellular growth and induced cell c
70 During charging, the oxidation reaction at significantly reduced charge potentials mainly takes pla
72 Conditional deletion of Npas4 in the NAc significantly reduced cocaine conditioned place preferen
74 However, daytime, but not nighttime, warming significantly reduced community temporal stability mainl
75 VD and overall PFVD of choriocapillaris were significantly reduced compared to controls in CRVO group
76 (p < 0.001) and PFVD of choriocapillaris was significantly reduced compared to controls in the affect
77 s that the Zr-Zr distances in this glass are significantly reduced compared to those quenched without
78 with very low birth weight, cBF volumes were significantly reduced compared with term-born adults (-4
80 ents with moderate to severe DG, relamorelin significantly reduced core symptoms of DG and overall co
86 pre-clinical and clinical individuals showed significantly reduced de-adaptation performance after th
87 Stable knockdown of ACTN4 by shRNA in HPCs significantly reduces dexamethasone-mediated induction o
88 imaging of zebrafish muscle fibers, we find significantly reduced DHPR levels, functionality, and st
89 lished DNA binding, mutation of Arg60 (R60Q) significantly reduced DNA binding, but retained a prefer
93 ared with placebo, prebiotic supplementation significantly reduced energy intake at the week 16 break
94 radiation, fat-1 transgenic mice exhibited a significantly reduced epidermal hyperplasia, oxidative s
96 ted region and its co-expressed genes showed significantly reduced expression after P. syringae inter
97 ed the SD protein complex in podocytes, with significantly reduced expression and altered localizatio
98 in Pax9-deficient embryos is accompanied by significantly reduced expression of Axin2, an endogenous
100 ncharged solutes is a promising approach for significantly reducing faradaic energy losses in closed-
104 incidence of postdural-puncture headache was significantly reduced from 11.0% (95% CI 9.1-13.3) in th
105 s or influenza virus revealed comparable and significantly reduced generation of Ag-specific CD4(+) T
109 f OG but not 5-(tetradecyloxy)-2-furoic acid significantly reduced hamster ear sebaceous gland size,
112 with lower RV ejection fraction (<41%) had a significantly reduced heart rate recovery in comparison
114 ly inactive dominant-negative GODZ construct significantly reduced HSV-1 replication in vitro and aff
115 ated proinflammatory cytokine production and significantly reduced human leukocyte antigen - antigen
118 bitor MCC950 or with extracellular potassium significantly reduced IL-1beta cleavage and release in r
119 In vivo blocking of beta2 integrins (CD18) significantly reduced ILC2 numbers in the lungs but did
120 SF neutralization in diet-induced obese mice significantly reduced immunosuppression, intratumor vasc
123 f the first beta-strand of Het-s fibrils, is significantly reduced in both Het-s/GroEL aggregates and
125 a-defensin antimicrobial peptide levels were significantly reduced in burn patients at 1 and 40 hours
126 um amyloid A and quality-of-life scores were significantly reduced in canakinumab-treated but not in
128 ervation of sweat glands in the footpads was significantly reduced in db/db mice compared to control
130 are mainly expressed in skeletal muscle, is significantly reduced in dystrophic muscles but is rescu
135 ng protein alpha (C/EBPalpha) expression was significantly reduced in MDSCs from tumor-bearing mice c
136 ation index (an indirect measure of SCD) was significantly reduced in nonobese asthma patients and in
137 ed beta-arrestin-dependent ERK activation is significantly reduced in PI3KgammaKO MEF, suggesting acc
138 transcript in human mammary epithelia but is significantly reduced in precancerous ductal carcinoma i
139 bcortical network global efficiency was also significantly reduced in psychotic disorders (F3,587 = 4
142 days after treatment, gametocyte density was significantly reduced in the DP-PQ arm relative to the D
143 having had asthma medication prescribed was significantly reduced in the fish oil group compared wit
145 roinflammatory cytokine interleukin 17A were significantly reduced in the krill oil group, compared w
146 of STAT5B on the JAK2-dependent Y699 site is significantly reduced in the liver and skeletal muscles
147 n and responsiveness along with H3K4me2 were significantly reduced in the livers of Nr2e3(rd7) (Rd7)
148 ed: (1) the mean melanopsin-mediated PLR was significantly reduced in the mild and moderate-severe gr
149 edian duration of acyclovir therapy was also significantly reduced in the postimplementation group (2
150 nown to inhibit presynaptic GABA release was significantly reduced in the RVM of CFA-treated rats com
152 idence of SSI at 30 days postoperatively was significantly reduced in the treatment group compared wi
153 Medial apoptosis and proliferation were both significantly reduced in these mice compared to control
155 e, while the LPS-induced TLR3 expression was significantly reduced in TLR4(-/-) and Myd88(-/-) mice a
156 valence of oral HPV16/18/6/11 infections was significantly reduced in vaccinated versus unvaccinated
158 ice, which are resistant to cleavage, showed significantly reduced infarct sizes and improved systoli
163 eferentially to TRAIL receptors 1 and 2 with significantly reduced interaction with the decoy TRAIL r
165 tion in sensory response by HOCl, leading to significantly reduced itch and inflammation in vivo.
167 DEK or treatment with DEK-targeted aptamers significantly reduces joint inflammation in vivo and gre
169 and acute mouse models of CCM3 loss in vivo, significantly reducing lesion burden and extending longe
170 in vivo with NIL in combination with WNT974 significantly reduced leukemic stem and progenitor cell
173 ition, colonies with a propolis envelope had significantly reduced levels of AFB clinical signs two m
175 the 12-week study, rats in both strains had significantly reduced LV fibrosis and improved vascular
176 model of sclerodermatous cGVHD, pirfenidone significantly reduced macrophages in the skin, although
179 78 weeks), the annualized bleeding rate was significantly reduced (mean rate, 11.1 events per year [
180 step in 27-hydroxycholesterol biosynthesis, significantly reduces metastasis in relevant animal mode
181 olone also prevented gut wall disruption and significantly reduced morphine-induced constipation.
182 te and intradimer and interdimer interfaces, significantly reduce MT stability, and cause severe neur
183 een RO treatment and final pH adjustment can significantly reduce NDMA re-formation by minimizing the
184 es for an ideal vaccine candidate, including significantly reduced neuroinvasiveness, induction of st
185 tion and NF-kappaB nuclear translocation but significantly reduced NF-kappaB DNA binding and phosphor
186 activation was also detectable, as marked by significantly reduced Nos2 and Il1b mRNA levels and decr
187 ed multipotent progenitors (MPPs) revealed a significantly reduced number of HSCs, likely owing to in
188 otelemetry, this is eventually offset by the significantly reduced number of mice needed to conduct p
189 and plasmablasts in periphery, they produced significantly reduced numbers of LLPCs following immuniz
190 nt up to age 6.5 years was associated with a significantly reduced odds of both atopy and "any allerg
192 nd nebulizer gas pressure it was possible to significantly reduce or even eliminate the impact of mat
193 f DG (composite or individual symptoms) were significantly reduced over the 12-week study period in a
194 asing the frequency of household wet mopping significantly reduced p,p'-DDT and p,p'-DDE exposure.
195 tested, we found increasing access to water significantly reduced p,p'-DDT exposure and increasing t
196 rther, siRNA knockdown of endogenous GATAD2B significantly reduced P4-PRWT transrepression of COX-2 a
198 nds to PapMV nanoparticles and its depletion significantly reduces PapMV's interaction with immune ce
201 ering RNAs (siRNAs) against COX-1 and COX-2, significantly reduced PGE2 production, as well as PSaV r
202 Deletion of the genes encoding these enzymes significantly reduced phage replication and the generati
203 ureus However, disruption of any two systems significantly reduced Pi accumulation and growth in dive
204 hosphorylated SNAP-23 mutant (Ser95-->Ala95) significantly reduces PKM2-mediated exosomes release whe
206 f erythrocytes and blood-borne pathogens are significantly reduced prior to the development of the ne
207 ELP matrix administered prior to irradiation significantly reduced radiation-induced pain after 3, 7,
208 and indicated improved overall survival and significantly reduced rates of relapse in lestaurtinib-t
209 F plus LD treatment is feasible and safe and significantly reduces rates of permanent shunt dependenc
211 approach encountered difficulties due to the significantly reduced reactivity of the 6-position of th
212 l pineapple vinegar, whilst off-flavors were significantly reduced relative to the initial wine.
218 HT during flowering and early grain filling significantly reduced seed-set and 1000 grain weight, re
219 sociated with endo-lysosome rupture and have significantly reduced seeding activity compared to recom
220 Inhibition of GAP-43 expression by shRNA significantly reduced seizure duration and severity in C
221 conditions, the AML patient cells exhibited significantly reduced sensitivity to 12% of the tested c
222 , the cue paired with TMS to target 1 showed significantly reduced skin conductance responses, wherea
224 ons in leaf gas exchange, barley plants with significantly reduced stomatal density show no reduction
225 enhancement (LGE) and low lateral MAPSE had significantly reduced survival compared to those with LG
226 SNOR KO animals receiving WT bone marrow had significantly reduced survival following P. berghei ANKA
229 ith an inhibitor of exosome release, GW4869, significantly reduces survival in co-cultured epithelial
230 r both SI and V5/hMT+, but not the PPC site, significantly reduced tactile direction discrimination.
231 crease the incidence of these conditions may significantly reduce the burden of inpatient ophthalmic
232 ine therapy for apnea of prematurity did not significantly reduce the combined rate of academic, moto
233 uracy of computational inference methods can significantly reduce the cost and time of subsequent val
235 opagation, a time-consuming process that can significantly reduce the effectiveness of vaccination pr
236 that in vivo blocking of CXCL1 and CXCL2 can significantly reduce the Mycobacterium tuberculosis-indu
237 andomly and sums them into one super shot to significantly reduce the number of wavefield simulations
238 (miR-9) modified BMSCs (pri-miR-9-BMSCs) can significantly reduce the pancreatic edema, infiltration,
241 Results In mice, olaparib, but not iniparib, significantly reduced the (18)F-FTT AUC in the spine (me
242 y secretions with a KLK5-selective inhibitor significantly reduced the activation of influenza A/Scot
243 trial, we showed that high-dose simvastatin significantly reduced the annualised rate of whole brain
244 presence of the alcohol infusion, nalmefene significantly reduced the BOLD response in the striatal
245 hat incubation with specific anti-CD73 serum significantly reduced the ecto-AMPase activity in the no
250 ession, normalized chloride homeostasis, and significantly reduced the glutamatergic rMF sprouting wi
252 outpatient or community-based NAI treatment significantly reduced the likelihood of requiring hospit
255 ibitor 3,4-dimethylpyrazole phosphate (DMPP) significantly reduced the N2 O production from these pat
256 omized trial, the routine use of pasireotide significantly reduced the occurrence of POPF without inc
258 nistered after chemotherapy and trastuzumab, significantly reduced the proportion of clinically relev
259 observed that the cwn-2 and cfz-2 mutations significantly reduced the reconnection possibilities of
260 , random assignment to 1 year of trastuzumab significantly reduced the risk of a disease-free surviva
262 Relative to placebo, evolocumab treatment significantly reduced the risk of the primary end point
263 point mutations at the interaction interface significantly reduced the secretion of effector proteins
264 ric obstruction, pretreatment with dasatinib significantly reduced the upregulation of profibrotic ma
265 In this study, we found that the EPE peptide significantly reduced the viability of not only BRAF, bu
266 lockade of gap junctions or ablation of Cx36 significantly reduces the ability of mice to discriminat
267 NR4A2 and NR4A3 homologs in zebrafish larvae significantly reduces the absolute neutrophil number wit
270 ne in Hu-mice, but not the parenteral route, significantly reduces the humanlike lung tuberculosis ou
271 a subunit of the interleukin-5 receptor that significantly reduces the incidence of asthma exacerbati
272 nonflat and irregularly shaped surfaces but significantly reduces the interfacial fracture strength.
274 th metalloporphyrin cobalt protoporphyrin IX significantly reduces the loss of body weight due to hRS
277 t 20 mug/mL) retain potent activity in vivo, significantly reducing the burden of VRE in infected wor
279 TEC-specific Irf4 deficiency resulted in a significantly reduced thymic Treg compartment and increa
280 a reconfigurable molding technology that can significantly reduce time, costs, and waste by shaping v
281 the production of LTB4 (23.7% decrease) and significantly reduced TNF and IL-12 levels in the gingiv
282 rative CAant (0.97 +/- 0.30 diopter [D]) was significantly reduced to 0.63 +/- 0.34 D (P < .001).
283 hat WT mice treated with CLP for 2 weeks had significantly reduced trabecular bone volume and cortica
284 ed macromolecules across cell monolayers but significantly reduces transepithelial electrical resista
286 ive transfer of HDAC11KO T cells resulted in significantly reduced tumor burden in a murine B-cell ly
287 E.G7-OVA tumor-bearing mice with Lp/OVA/StII significantly reduced tumor growth being more noticeable
288 ur results indicated that voluntary exercise significantly reduced tumor number in a strain dependent
289 vorinostat and the IKK inhibitor Bay 117085 significantly reduces tumor growth in nude mice compared
290 EST in hormone-refractory CWR22Rv1 PCa cells significantly reduces Twist1 and CD44 expression, cell m
291 r-specific MHC I antibodies, mTOR inhibition significantly reduced vascular injury, ERM phosphorylati
292 ents with CPVT, flecainide plus beta-blocker significantly reduced ventricular ectopy during exercise
298 stathmin suppression in neuroblastoma cells significantly reduced whole body, lung, kidney and liver
299 unction structure and function, and this was significantly reduced with DPP4 inhibitor treatment.
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