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1  statistic grounds, extrathyroidal extension signified a strong risk of liver metastasis (19%, OR 23)
2 ozygous mutation, i.e., p.Tyr64Cys in CDC42, signifies a clinically recognizable novel syndrome that
3 etes in distress levels, which statistically signifies a direct relationship to cortisol was not pres
4                           Lymphatic research signifies a field of rapid progression in recent years.
5 emerge, subclinical atrial fibrillation (AF) signifies a future challenge to health care systems.
6 s evident that dysregulated lipid metabolism signifies a key element in many pathological conditions.
7 ne transmission by a selfish genetic element signifies a mechanistic variation within the shared them
8  dose-response patterns identified by TOXcms signifies a metabolic response to a different protein ta
9 revealed for the insertion of carbide, which signifies a novel biosynthetic route to complex bridged
10 from terrestrial or oceanic environments but signifies a potentially major, but largely unknown, role
11                   This expression clustering signifies a shared pathogenic group of genes that GATA6
12 trongly influenced by the temperature, which signifies a strong temperature dependent exciton recombi
13                     The mosaic antigen array signifies a unique approach that subverts monotypic immu
14 er and drier conditions on the mountain, and signify a bleak outlook for silverswords if these trends
15                                These results signify a critical role for acetate consumption in the p
16 al nanomaterials and analytical technologies signify a foremost possibility for the advance of electr
17                                These results signify a greater role for the thalamus in visual proces
18 ate the use of candidate fecal indicators to signify a health risk from enteric pathogens in sewage-i
19                       Our open-source labels signify a key step towards a unified mouse brain atlas.
20                     In all, the Scl proteins signify a large family of structurally related surface p
21 lications of end-stage chronic liver disease signify a major cause of mortality worldwide.
22 th literacy of patients with retinal disease signify a need for more health literacy research in the
23 tebrate developmental eye disorders, and may signify a new developmental pathway.
24 T) indicating adequate fluorescent signal to signify a positive result was established along with the
25                                     Our data signify a possible role for using physiologic monitoring
26 act on early rod photoreceptor viability may signify a previously underestimated critical role in cir
27 evant for Abeta-directed diagnostics and may signify a role of SST14 in the etiology of AD.
28                                These results signify a time-dependent energy distribution among vario
29  seen in scleroderma lesions might therefore signify a tissue-autonomous protective attempt to restri
30                                 Our findings signify a unique transcriptional regulatory role to the
31 d by naive target-decoy and MAYU approaches, signifying a 6-fold increase in the number of UCB protei
32 l over those reported for Pt-based catalysts signifying a capability of scaled hydrogen production.
33 urning results from an 'off' Ca(2+) response signifying a chemoattractant stimulation decrease and, t
34 havioral context, with powerful oscillations signifying a cortical state under inhibitory control in
35 tained in patients dying at onset of T1D and signifying a decisive role for bacteria in eliciting an
36 se in the film, and a decrease in DeltaR(m), signifying a deswelling of the film, were observed durin
37 tivation was enhanced only by wild-type D2R, signifying a dissociation in the mechanisms that underli
38 was observed in two different breeds of pigs signifying a general effect.
39 and 14 of 14 isolates from western Cambodia, signifying a hard transnational selective sweep.
40 l bleeding died within 60 days of admission, signifying a high burden.
41 mented epithelium has plentiful melanosomes, signifying a highly adapted eye for maximum light percep
42 d retention of GFP-Dectin-1 to the phagosome signifying a link between Syk and intraphagosomal pH.
43 ing transgenes and chemical modulation, thus signifying a milestone in advancing our understanding of
44 r in flow stress variation with strain rate, signifying a nonlinear coupling between thermally activa
45 aA modulate the activity of the Frd complex, signifying a potential regulatory chaperone-like functio
46 rigger belowground accumulation of the mir1, signifying a potential role of long-distance signaling i
47 and diminished intralineage diversification, signifying a reduced substrate for mounting novel respon
48 esistance (17.44 Omega) and a long lifetime, signifying a reduction in recombination losses.
49 one positive selection throughout evolution, signifying a selective benefit, but go on to show that s
50 d to increase with temperature due to hemin, signifying a spin exchange between the iron center and t
51 action between time and presence of sepsis - signifying a steeper increase in PSP levels in septic pa
52 ions in translocated MYC in knock-out cells, signifying a successful targeting of the malignancy.
53 e AAV9 also significantly extended lifespan, signifying a treatment option for patients for whom HSCT
54 cal Wnt pathways regulate membrane potential signifying a very early event in the signal transduction
55      These and other putative biomarkers may signify aberrant oncogene pathway activation and provide
56 creased urine podocin/creatinine ratio in TG signifies accelerated podocyte loss.
57  histone marks and DNase I hypersensitivity--signifying accessible, permissive chromatin-at most of t
58 e, periodate reactivity of the final product signifies acquisition of a ribose sugar with an intact 2
59 in serum creatinine (DeltaSCr) from baseline signify acute kidney injury (AKI) but offer little granu
60  phase III pivotal trials for heart failure, signifying adequate enabling safety and efficacy data fr
61 ion with the phagolysomal marker LAMP1; this signified altered intracellular trafficking and decrease
62    Exosome-shuttled proangiogenic miRNAs may signify amplification of stem cell function and may expl
63  VHL knockout cells and whose overexpression signifies an aggressive form of ccRCC in the cancer geno
64                             Drug repurposing signifies an appealing approach to enhance the activity
65 conic phrase "a shot heard 'round the world" signifies an exceptional event.
66  stem cell-derived cardiomyocytes (iPSC-CMs) signifies an important advance in the study of genetic d
67 without any tissue preparation, this finding signifies an important step toward the development of an
68 , suggesting that sensorimotor beta-bursting signifies an inhibited motor system, which has to be ove
69                         The RAC and DBC both signify an advance in the description and differentiatio
70  genes in the sphingolipid pathways that may signify an alternative defense system.
71 hite matter and that these abnormalities may signify an early feature of the disease process.
72                          Thus, these results signify an importance to study those yet to be defined h
73  supplemented with KH(2)PO(4.) These results signify an increased plant-mediated dissolution, uptake,
74                                      We also signify an isoform-specific role for Akt/PKB in RXR-sele
75                             These challenges signify an unmet need for drug carriers that can cross t
76 core on the modified Rankin scale of 0 to 2, signifying an absence of or minor neurologic deficit, wa
77 es survival in co-cultured epithelial cells, signifying an important role of CAF exosomes in chemothe
78  B-cell populations and antibody production, signifying an increased humoral immune response.
79 verifies core fucosylation while its absence signifies antennae fucosylation.
80 Pepsin was detected in 11 of 15 BALF samples signifying aspiration (median: 18 ng/mL; range: 0-43).
81 e [the deflection within the venous waveform signifying atrial contraction] at or below baseline; DV
82              Decreased Bcl-2 gene expression signified atrophic gastritis and IM in presence of cance
83 at relate to what those stimuli have come to signify behaviorally: when to expect future reward and a
84 ce but not in OASIS knockout mice after UUO, signifying Bst2 functions downstream of OASIS.
85 e displayed enhanced tactile sensitivity, as signified by a lower latency in the sticky-tape removal
86 he underlying states that people believe are signified by a smile.
87  developed in parallel with dendritic damage signified by dendritic beading.
88 der similar conditions as nondiabetic PTECs, signified by deregulation of fibrotic and transport-asso
89      We find that chronic postviral disease (signified by formation of excess airway mucus and accumu
90                       SAR324's metabolism is signified by genes that encode a novel particulate hydro
91 e MAE did not modulate sympathovagal balance signified by HRV at either 30 min or 60 min following ex
92                                      This is signified by increased numbers of exhausted CD21(neg) me
93 ntrast, successful movement cancellation was signified by increased phasic beta-bursting over fronto-
94  fluorescence observed in protein fibrils is signified by large reductions in the fluorescence intens
95 ssociated colitis in critically ill patients signified by microbiota depletion, and reestablishment o
96 tern upon FPR2 sensing of PSMalpha peptides, signified by the ability to induce increased intracellul
97 ate that small bacterial cell size, which is signified by the absence of DivIVA, and the presence of
98 e field of novel therapeutics in SLE and was signified by the effort to target specific signaling pat
99 The translational value of these findings is signified by the fact that CAMK4 is increased in podocyt
100                         First, networks were signified by the sustained element, which statically mod
101                                RPE migration signifies certain RPE plasticity.
102             Differential co-expression (DCX) signifies change in degree of co-expression of a set of
103  analysis, and H-bonding arrangements of one signified compound prepared is presented.
104 sting that patterns of mGluR5 expression may signify continuing epilepsy development or its resolutio
105 en isotope enrichment (delta(18)O) signature signifying deeper water capture, between 10% and 35% gre
106  isotopic ratio of (18)O to (16)O signature, signifying deeper water capture, between 22% and 30% gre
107  report that epigenetic priming of enhancers signifies developmental competence during endodermal lin
108  afferent sensory inputs to the brain and/or signify differences in sensory gating of cardiac-related
109 ions between lipid groups at M1, M3, and CB, signifying differences in lipid metabolism.
110 toantibody responses to FcepsilonRIalpha may signify different stages in the disease course.
111 vements in cerebral glucose consumption that signifies disease progression.
112 patiotemporal patterns of neuronal synchrony signify diverse neurophysiological disruptions and patho
113                         CYR61 expression may signify early perturbation of the microenvironment befor
114 rior to the chemical steps of recombination, signifying early commitment to a productive reaction pat
115  curve percentages (%AUC) were calculated to signify efficacy.
116 M-/-) mice have low ATP and high AMP levels, signifying energy deficit.
117 shows that this coefficient often exceeds 1, signifying essential multidimensionality of those system
118 alin fixed paraffin embedded (FFPE) tissues, signifying FFPE tissues can serve as biospecimens for ca
119 mine was shown to stimulate cAMP production, signifying functional beta1-AR expression.
120 growth defects in an allele-specific manner, signifying functional interactions.
121 ion by T cells, and whether CD100 expression signifies functionally competent effector cells.
122                                       Peak I signified glutenins (30-130kDa), peak II as gliadins (20
123                                Although ELSs signify good prognosis in certain malignancies, we found
124               Variously colored oil droplets signify high color vision ability.
125                                    They also signify high levels of genomic instability that sensitiz
126 OMT diplotypes coding for low-activity COMT, signifying impaired catabolism of catecholamines.
127  Klf5 withstanding epithelial damage further signifying importance of Klf5 in colonic homeostasis.
128 nergy CT and low-energy near-IR excitations, signifying importance of these push-pull systems for opt
129 f homologous recombination status), but also signify important applications of selective PARP-1 inhib
130 ale scores (p<.05), with decreases in scores signifying improvements in executive functioning.
131 admission and readmission diagnoses that may signify in-hospital or postdischarge quality problems.
132 orporation of C4 resources into hominin diet signifies increased dietary breadth within hominins and
133 ion per chromophore over a free chromophore, signifying increased electronic coupling.
134  bacteria can be indicator molecular species signifying initiation of biofilms on membrane surfaces,
135 sound objects, whereas beta-band oscillation signifies involvement of the action-perception cycle, an
136 disease (AD) and tracks disease progression, signifying its importance in AD.
137  heme iron reduction by FdR in the HbN, thus signifying its involvement during intermolecular interac
138  biological samples (urine and blood plasma) signifying its potential as an alternative tool for BAs
139 stored DDR function, and increased survival, signifying its role as a key contributor to stem cell ra
140 epsis remain understudied and could possibly signify lapses in care and missed opportunities for inte
141 r results support the hypothesis that LLSVPs signify large-scale mantle upwelling in two antipodal re
142 y 23 cal mol(-1) K(-1) per nucleotide, which signifies liberation of manifold frozen degrees of freed
143 c characterization could yield biosignatures signifying life.
144 radients reflect shifts in phenotypic optima signifying local temperature adaptation mediated by soil
145 ns within the caldera are also not likely to signify magma inflow.
146 REE profiles indicative of simple diffusion, signifying minimal alteration, have been proposed as ide
147  predictors), low scores were interpreted as signifying minimal risk, with little treatment necessary
148 ores range from 0 to 176, with higher scores signifying more severe disease).
149 e motion from higher-order correlations that signify motion in natural environments.
150                    Cardiac biomarker release signifying myocardial injury post-transcatheter aortic v
151  the role of H. pylori remains controversial signifying need for further research.
152 expression, whereas howls, hisses, and cries signify negative vocal communications.
153  cue; this combination of Fear + Safety Cues signified "no shock." This neural population consisted o
154 rocytes do not migrate into neuronal domains signifying nonreciprocal chemorepulsion.
155                                These results signify not only the role of RORalpha in the molecular p
156 e distinctly unlike self and viral antigens, signifying novel groups of potentially highly immunogeni
157  cancer cells disrupts nucleolar morphology, signifying nucleolar stress.
158 atitis B virus (HBV)infection but might also signify occult HBV infection.
159                     An 8-gene Tfh signature, signifying organized antitumor immunity, robustly predic
160  with LVWT, generally without a clear cutoff signifying pathologic transition.
161  was evaluated in a prespecified subgroup of SIGNIFY patients with angina (Canadian Cardiovascular So
162 ts responding to a shallow gradient of PDGF, signifying polarization.
163 y transcriptionally repressed in cancers and signifies poor prognosis of breast cancer patients.
164 learning, they initially take that effort to signify poorer learning.
165                                         Mews signify positive vocal expression, whereas howls, hisses
166 s ranging from 0 to 21; scores higher than 8 signify possible anxiety or depression.
167 ne in Patients with Coronary Artery Disease (SIGNIFY) QoL substudy.
168 w greater than expected for a given age also signify rapid disease progression.
169                                 Our findings signify relationships between drug distribution in fibro
170                                    Bivalency signifies repressed but activatable states of gene expre
171 with unencumbered, nasal O(2), and NIOV+Air, signifying respiratory muscle unloading.
172 luent absence of autofluorescence, a measure signifying RPE loss, was a significant predictor of visu
173 y, this review concludes with future outlook signifying some challenges of these nanoengineered chole
174 OCT, an intrascleral hyper-reflective shadow signified stable haptics without any optic tilt.
175      For the sample size included, TI > 0.36 signified statistical significance at the 0.05 level.
176 he radial component of inward traction force signifies successful actin-cable segment switching.
177                                         This signified that DOM removal by coagulation can be achieve
178  interaction partners relative to the cortex signified that signals emanating from membrane-associate
179                               A ranking of 1 signifies that both the lipid class and adduct of the in
180                              For birds, this signifies that cryopreserving and regenerating a species
181 nly partially explained by subgroup analysis signifies that further research is necessary--particular
182 ysing two published breast cancer cohort, we signifies that MOVICS can serve a wide range of users an
183 d target analyte match, while a ranking of 3 signifies that neither the adduct or class match.
184                                 Our analysis signifies that the applied voltage-induced polarization
185  from 1:14 in 2005-2009 to 1:6 in 2014-2017, signifies that the national notification system, which r
186                                  This result signifies that the Orbitrap is an appropriate technique
187 overy of an RNA element that inactivates Rho signifies that the specificity of nucleic-acid binding p
188                                  This result signifies that there is energy value within used modules
189                         A designation of CoE signifies that these institutions deliver high-quality c
190                                  Our results signify that by identifying mechanisms through which mix
191 kine production and disease progression, and signify that CNS-DCs and circulating DC precursors might
192 ses in maximal diameter of cerebral arteries signify that elevations in brain blood flow may occur du
193                       If confirmed, it would signify that geostrophic eddies not only contain the mos
194                       Such changes in traits signify that human actions can lead to cases of increase
195 mulus phase and syllable identification, and signify that the origin of this phase relationship could
196 cific properties of the environment, such as signifying that a particular position is near a doorway
197 (IFN-gamma) in human whole blood cell assay, signifying that anti-inflammatory factors are also prese
198 tating the putative manganese ligand Asp526, signifying that both metals likely bind to the same site
199 ne and the industrial solvent chlorobenzene, signifying that electrocatalytic treatment has tremendou
200 itness as a result of synergistic epistasis, signifying that epistasis may be a critical factor in th
201 modifications neighbouring the acidic patch, signifying that it may act as a tunable interaction hots
202 icient to ablate miR-890 radiosensitization, signifying that miR-890 functions by regulating multiple
203 shift was also observed in septic monocytes, signifying that patients suffering from sepsis-induced i
204 h no additive effect in WASp(-/-) platelets, signifying that phosphorylation is critical for WASp-lim
205 dian odds ratio for RPM enrollment was 3.43, signifying that physician or institutional factors are a
206 th solid-state structures also gave evidence signifying that point chirality adjacent to triphenylsil
207 eing detected in the underlying HepG2 cells, signifying that some of the plasmid was transported acro
208 eletion reduced Flt3L-mediated DC expansion, signifying that STAT3 had reciprocal effects on suppress
209 with mutations in the Pol2 CTD-binding site, signifying that the Spt5 and Pol2 CTDs cooperate to recr
210  the superconducting transition temperature, signifying that the superconducting state is categorized
211 lybin derivatives, namely DHS, 7OM, and 7OG, signifying that their efficacy and toxicity should be ev
212 isplatin-resistant cells as wild-type cells, signifying that they circumvent cisplatin resistance.
213  in the area of the non-coding transcriptome signified the crucial roles for RNA regulatory networks
214 f the divalent ions to retain the suspension signified the electrostatic interactions in the matrix s
215 ble Fe(II) and increasing accumulation rates signified the role of iron as terminal electron acceptor
216  properly functioning adaptive immune system signifies the best features of life.
217     The dramatic improvement in the activity signifies the cooperativity between Ti and W and indicat
218 his is a somewhat trivial case, this example signifies the extraction of useful physical and structur
219                 We argue that the phonon gap signifies the formation of short-lived nanometre-scale l
220                                  Our finding signifies the importance of investigating the difference
221                          Overall, this study signifies the importance of PG cross-link cleavage and i
222 itional value and antioxidant activity which signifies the importance of this vegetable for the Medit
223                                    This work signifies the important role of pili in corynebacterial
224 ignificant milestone in rift evolution as it signifies the localization of crustal extension and rift
225 and chemical activity of nanoparticles (NPs) signifies the possibility of converting the spin angular
226  This hitherto unexplained function of SMAR1 signifies the potential of this unique scaffold matrix-a
227  polymer, typically a cross-linked hydrogel, signifies the presence of the molecule of interest.
228 thering of a pair of plasmids to chromosomes signifies the replication-independent component of segre
229 n species in up-regulated genes after 10 min signifies the role of signal transduction events and rea
230 mediated IL-6/Stat3 signaling activation and signifies the therapeutic potential of blocking MMP-2/al
231 s with a low electrochemical band gap, which signifies the tuning of highest occupied molecular orbit
232  of the Li-O2 battery electrolytes; our work signifies the use of SEIRAS technique in this direction.
233 al nonproliferative melanocytic pigmentation signifies the usually small number of conjunctival basal
234                    As such, our findings may signify the ability to elucidate a putative surrogate ne
235              These unique isotope signatures signify the breakdown of the traditional theory of isoto
236   The abnormal neural integration mechanisms signify the contribution of cortical network dysfunction
237 ive secretome analysis in 13 cell lines that signify the different NE lung cancer subtypes.
238                           These observations signify the dominant negative nature of mutations.
239                                 Our findings signify the dynamic and reciprocal cross-talk between tu
240 uture surveillance by providing markers that signify the emergence of viruses with enhanced zoonotic
241  sizes, and excellent electrical performance signify the high quality and scalable synthesis of the m
242                            Thus, our results signify the importance of AIB1 in CRC and demonstrate th
243                            Our findings thus signify the importance of carrying out explicit electron
244                                 Our findings signify the importance of the cellular trafficking prope
245 lterations are becoming more evident and may signify the need to age-stratify treatment regimens.
246 ty, first sexual intercourse and first birth signify the onset of reproductive ability, behavior and
247 c SO2 emissions since approximately 1980 and signify the positive impacts of landmark environmental l
248                   Collectively, our findings signify the presence of an nprl3-linked multiglobin gene
249                             Our observations signify the presence of distinct experimental fingerprin
250                               These findings signify the prognostic value of serum chloride and poten
251                                  Our results signify the role of the I507-ATC-->ATT SCC in the DeltaF
252 versible, sedation-related delirium does not signify the same poor prognosis as persistent delirium.
253 teristic wetting velocity was put forward to signify the strength of the inherent contact line fluctu
254                                 Solar flares signify the sudden release of magnetic energy and are so
255                                     This may signify the underlying financial incentives to preferent
256 WD skew does not impact the strain at break, signifying the ability to influence HDPE processing with
257 e of adjacent channels under liquid loading, signifying the achievement of interference-free MQCM.
258 5KO BM cells survived in adult p75KO tissue, signifying the additive negative roles of tissue aging c
259 appa index showed excellent agreement (0.88) signifying the capability of this method to overcome the
260 tern of water after a sudden cooling to 4 K, signifying the conversion of ortho-water to para-water o
261 llmark of the evolution of multicellularity, signifying the emergence of a new type of individual and
262 or-bearing mice that lacked bone metastasis, signifying the essential cross-talk between tumor cells
263 with a specific regenerative medicine focus, signifying the growth and widening appeal of this emergi
264 n the regulation of synaptic vesicle fusion, signifying the importance of alpha-syn-lipid interaction
265 iderably weaker than lateral hydrogen bonds, signifying the importance of lateral hydrogen bonds in s
266 ing methylglyoxal and oxidative stress, thus signifying the importance of these proteins in the maint
267 nge in intracellular redox potential of Mtb, signifying the importance of this operon in oxidative st
268 genous danger-associated molecular patterns, signifying the inflammatory potential of pyroptosis.
269 with the second of two phytoplankton blooms, signifying the influence of ocean biology on selective m
270  pairs of MDROs increased the risk of CAUTI, signifying the involvement of microbial interactions in
271 on, especially in polymicrobial co-cultures, signifying the need for analytical standardization of si
272 nd may come with substantial adverse effects signifying the need to find novel treatments.
273 ntrations were primarily driven by variables signifying the physical footprint of the ME, such as cur
274 , a donor sequence number (DSN) was provided signifying the position of a recipient on the list for a
275 strongly correlated with abundance of intl1, signifying the potential importance of mobile genetic el
276 decomposed by a single bacterium per second, signifying the presence of a highly active catalase.
277  to RNA, and formation of large condensates, signifying the role of arginine in driving proper RNA in
278 alteration in the expression of the act gene signifying the role of GidA in positively regulating Act
279 maternal to placental to fetal compartments, signifying the selective transfer of PEMT-PC to the fetu
280 the activity of Gtfs and S. mutans biofilms, signifying the specificity of the lead compound.
281 r failure-to-rescue rates in the elderly may signify their diminished physiological reserve for survi
282 fer was also possible when ZnPc was excited, signifying their potential in light-energy-harvesting de
283 exhibit distinct lipid-binding specificities signifying their various biological roles that dictate f
284 e genes and a single or multiple normalizers signified this research.
285 GTP-sensing activity of PI5P4Kbeta in cancer signifies this lipid kinase as a cancer therapeutic targ
286 omplete remission (CR) and partial remission signify treatment effects that are consistent with disea
287 iation generated by a commercially available Signify ultraviolet (UV)-C light source at 254 nm.
288 viral infections, the deranged B cell subset signifies uncontrolled disease.
289  from GDM to T2D and that metabolite changes signify underlying pathophysiology for future disease de
290 b GTPases, Ypt1 (Rab1) and Ypt31/32 (Rab11), signifying unprecedented signaling crosstalk between GTP
291 categories of cell proliferation assays that signify various stages of the cell cycle: nucleoside-ana
292 to 5 (where 1 signifies very low value and 5 signifies very high value), 124 of 187 nurse managers (6
293                On a scale of 1 to 5 (where 1 signifies very low value and 5 signifies very high value
294 tes reflect hospital imaging use and perhaps signify vigilant, high-quality care.
295 dent nucleic acid "danger" signal, which may signify viral infection or local cell death, triggers Ga
296 to specific spatiotemporal correlations that signify visual motion.
297 2]; heat elevated above ambient temperature, signifying warm-blooded skin [3, 4]; and dark visual con
298 amics identifies a dimensionless number that signifies when the external viscosity can be important.
299                            The user can also signify which lipid classes an internal standard represe
300 ations, we find that the first defect event, signifying yield, is controlled by the intralayer spacin

 
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