ライフサイエンスコーパス: silencing element

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1 bp motif called the NRSE (neuron-restrictive silencing element).

2 uence located within a previously identified silencing element.

3 Thus, we conclude that the ZV, ZV', and ZIIR silencing elements act synergistically to repress transc

4 Cas9-mediated deletion of the silencing element alleviates WNT repression, but is, in

5 lysis in NIH3T3 cells suggests that multiple silencing elements and enhancing element(s) are involved

6 Presently, this temporal requirement of the silencing element appears to be a unique cis activity in

7 lt erythropoiesis indicating that additional silencing elements are located upstream of position -463

8 Notably, these dispersed silencing elements can synergize to silence genes locate

9 Several previously identified silencing elements derived from alternatively spliced ex

10 We show that at the HML locus, at least four silencing elements engage in multiple functional interac

11 Tissue-specific silencing elements have been identified that are require

12 An insertion 3' of the downstream silencing elements, however, has no effect on splicing.

13 ounteracting the function of a translational silencing element in its 3'-UTR defined previously.

14 We here determined the minimal silencing element in the Cp 3'-UTR by progressive deleti

15 CX and REST co-occupy the neuron-restrictive silencing elements in the promoters of a subset of REST

16 Deletion of an upstream silencing element, matA SE, results in derepressed expre

17 tays active throughout L3, while an adjacent silencing element nucleates increasing levels of epigene

18 SBE2 overlaps the ZEB-binding ZV silencing element of Zp.

19 Thus, we conclude that ZIIR is a potent silencing element of Zp; it plays a key role in establis

20 und to a cognate element (neuron-restrictive silencing element) on the Crh gene.

21 MAZ4 insertions 5' to the upstream silencing elements or between exon IIIb and downstream s

22 The repressor element-1/neuron-restrictive silencing element (RE-1/NRSE) mediates transcriptional r

23 ement repressor element 1/neuron-restrictive silencing element (RE1/NRSE).

24 elements or between exon IIIb and downstream silencing elements result in decreased silencing.

25 In so doing, we identified a 258-bp "silencing element" (SE) in the 5' portion of the gC codi

26 n a particular location is affected by other silencing elements (silencers and protosilencers) presen

27 etion analysis localized 5' and 3' "enhancer-silencing elements" to -2140 to -2000 and +1865 to +2180

28 A region containing a potential silencing element was also identified.

29 Two silencing elements were found within this 101 nt region:

30 A silencing element, ZIIR, is located between the ZID and

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