ライフサイエンスコーパス: silent

1 rons in rested flies tend to be electrically silent.

2 htly, while the pseudohexagonal faces remain silent.

3 Her past medical history was silent.

4 fficult process to study as it is clinically silent.

5 V-infected macrophages remained surprisingly silent.

6 the early stages of infection are clinically silent.

7 ions, most secondary metabolism genes remain silent.

8 ary migration for which this simple model is silent.

9 ed into a deleted ICP4 locus remained almost silent.

10 the 70S ribosomes to form a translationally silent 100S complex.

11 ency to reduce surface logging and to become silent (21% of cases), whereas pilot whales increased su

12 ic regions, and most of these are clinically silent, a proportion of individuals with calcified cysti

13 sue microenvironment program macrophages for silent AC clearance.

14 d asymptote, in parallel with the apparently silent addition of new dendritic spines at P15 or the si

15 d, causing action potentials in an otherwise silent afference.

16 However, the number of formerly 'silent' afferents that became mechanosensitive was incre

17 s lost, rather than gained, sensitivity and 'silent' afferents that were mechanically insensitive and

18 mission from nociceptors and recruitment of 'silent' afferents.

19 suggesting that phosphocholine may act as a silent agonist.

20 Moreover, we provide evidence, using a silent allosteric modulator as an allosteric antagonist,

21 We estimate a 50% prevalence of silent AMR in DSA+ long-term recipients and conclude tha

22 chromosome (Xi) is largely transcriptionally silent and adopts an unusual 3D configuration known as t

23 ith fluctuation-driven transitions between a silent and an active attractor and assumed that neurons

24 As compared to Lpn, Llo is immunologically silent and fails to trigger the production of cytokines

25 lent histone modifications characteristic of silent and inducible loci.

26 sed celiac disease appeared to be clinically silent and remained undetected, but long-term outcomes h

27 l and electrical energy by means of durable, silent and scalable solid-state thermoelectric devices h

28 ory alkalosis (e.g. hypoxia) RTN neurons are silent and the excitatory input from the carotid bodies

29 rative myocardial infarctions are clinically silent, and asymptomatic troponin elevations have the sa

30 astic transitions between active, reversibly silent, and irreversibly silent states.

31 en in Eastern Nepal, is primarily clinically silent, and may be more common among girls.

32 s in comparison to a classical agonist and a silent antagonist.

33 ll-death forms disjunct from immunologically silent apoptosis are, in theory, more likely to be relev

34 yme active sites, yet has remained virtually silent as a probe in NMR spectroscopy.

35 n DA, and the collector current of NE became silent at approximately 20 mum.

36 ns of redundant codons to encode cPTMs with "silent barcodes" to trace multiple modifications within

37 ES") to discover small molecule elicitors of silent biosynthetic gene clusters.

38 s a composite of clinical ischemic stroke or silent brain infarction detected on imaging.

39 0.29 to 0.91; P=0.04), but the incidence of silent brain infarction did not differ significantly bet

40 f long-lived cells harboring immunologically silent but replication-competent proviruses - termed the

41 Most of the other mutants were remarkably silent, but a double mutant with His(273) and His(274) e

42 The bare complex is CD-silent, but coordination of an enantioenriched substrate

43 The source itself is electrically silent, but its location can be inferred by building iso

44 % of these synapses have been proposed to be silent, but most are labelled for AMPA receptors.

45 stent defective proviruses of HIV-1 are not "silent," but rather may contribute to HIV-1 pathogenesis

46 ancers through T cell factors (TCF) and kept silent by Groucho/TLE co-repressors.

47 ened during the swim segment, and clinically silent cardiovascular disease was present in an unexpect

48 hus needed, in particular for radiologically silent cases, which correspond to the recommended tissue

49 l algorithm for the evaluation of clinically silent CBD stones during routine cholecystectomy is uncl

50 regulating the expression of alpha-globin in silent cells.

51 arkers of the clinical disease, primarily on silent central nervous system lesions observed in postpr

52 lence, the primary CNS complications include silent cerebral infarcts (39% by 18 years), headache (bo

53 fusions Changing to Hydroxyurea [SWiTCH]) or silent cerebral infarcts (Silent Infarct Transfusion [SI

54 licenses reprograming of DNA methylation at silent CGI during progression.

55 L-segment intergenic region (IGR), and three silent changes in the polymerase gene that did not impac

56 channels without recruiting additional near-silent channels known to be activated by proteases.

57 ir2-interacting factor, is also required for silent chromatin cohesion.

58 esin embracing both sister chromatids within silent chromatin domains.

59 alized sites of cohesion where cohesin binds silent chromatin in a Sir2-dependent fashion.

60 f a transcriptionally active DNA region to a silent chromatin state.

61 cohesion are separable functions of Sir2 and silent chromatin.

62 ) spaces nucleosomes to promote formation of silent chromatin.

63 racteristics compatible with immunologically silent clearance of ACs; such characteristics include hi

64 agocytosis that produces an "immunologically silent" clearance of the apoptotic cells.

65 e that this regulation constitutes a global 'silent code' mechanism that controls the functional dive

66 tes recovery of recessive and phenotypically silent conditional mutations.

67 ioral reports (immediate button presses) and silent counting of the perceptual events.

68 y is increased dramatically by incorporating silent CRISPR/Cas-blocking mutations along with pathogen

69 s to the outcome of patients with clinically silent CS.

70 Silent disease (n = 44) was 5 times more common than man

71 causing breakdown of heritable tolerance in silent disease carriers generating gHAT outbreaks and se

72 Early detection of silent disease may help prevent progression to severe va

73 asymptomatic cardiac involvement (clinically silent disease).

74 gs point to a reservoir of transcriptionally silent, disrupted HPV16 DNA in morphologically normal ce

75 onsistent with the presence of functionally 'silent' dopamine vesicle clusters and represents, to the

76 ge scale transitions between active (up) and silent (down) states during quiet wakefulness or NREM sl

77 found that the vast majority of neurons were silent during exploration.

78 nded strongly to object motion, but remained silent during global image motion.

79 is generally thought to be transcriptionally silent during mitosis, technical limitations have preven

80 s the circuit mechanism keeping most neurons silent during ripples.

81 stimulus on the control site, they remained silent during the warming stimuli on the injected site.

82 ndrogens to drive expression of the normally silent E26 transformation-specific (ETS) transcription f

83 res disassemble to spherical structures with silent electronic circular dichroism spectra but which f

84 -zygotic transition (MZT), transcriptionally silent embryos rely on post-transcriptional regulation o

85 Silent encoding of multiple cPTMs can be readily incorpo

86 dition of new dendritic spines at P15 or the silent enlargement of synapses in adults.

87 Here, we demonstrate involvement of a silent epiallele in hybrid incompatibility.

88 e maps provide evidence for the existence of silent epialleles in plant genomes which, once identifie

89 The findings may indicate a silent epidemic in a rural area where severe symptomatic

90 contribute to cis inheritance of H3K9me and silent epigenetic states.

91 ministration generates AMPA receptor (AMPAR)-silent excitatory synapses within the basolateral amygda

92 uced NMDA receptor-containing, AMPA receptor-silent excitatory synapses, albeit in distinct cell type

93 , knockdown of SNORD27 activates previously "silent" exons in several other genes through base comple

94 apses are sparse, immature and functionally 'silent', expressing mainly NMDA receptors.

95 nonverbal vocalizations (e.g., crying), and (silent) facial expressions.

96 , we demonstrate that the analysis undergoes silent failure, resulting in reconstruction artefacts.

97 kills Escherichia coli in an immunogenically silent fashion.

98 villains in movies have been used since the silent film age.

99 d infected mice that universally expressed a silent (floxed) version of tdTomato.

100 herapeutic target, and work in this area was silent for decades.

101 Because silent gaps are not common in continuous flowing speech,

102 we can further evaluate undiagnosed cases of silent gastric perforations presenting with non-specific

103 and help gain insights into the mechanism of silent gene activation in fungal defense.

104 ch, we successfully used HiTES to activate a silent gene cluster in Streptomyces albus J1074.

105 ulation and chemical output of the countless silent gene clusters in Streptomyces spp.

106 assettes to exchange all native promoters in silent gene clusters with constitutively active promoter

107 The activation of a silent gene locus is thought to involve pioneering trans

108 eration (born during 1901-1924), 3.0% in the Silent Generation (born during 1925-1945), 1.0% in the B

109 DNA and initiate cooperative interactions at silent genes during development, cellular reprogramming,

110 In order to investigate the expression of silent genes in symbiotic systems, 136 fungi-fungi symbi

111 H3K27me3, which marks many transcriptionally silent genes throughout the mammalian genome.

112 significantly elevated in transcriptionally silent genes when compared with actively transcribed gen

113 ioneer factors function, how they can target silent genes, and their limitations at regions of hetero

114 macronucleus (MAC) and the transcriptionally silent germ-line micronucleus (MIC).

115 rangement accompanies differentiation of the silent germline micronucleus into the transcriptionally

116 ed increased levels of AMPA receptor (AMPAR)-silent glutamatergic synapses in this projection, accomp

117 by heterozygous expression of catalytically silent Gpx4.

118 H3K9me3 domains, which are transcriptionally silent, H3K9me2 domains are transcriptionally active, co

119 Transcriptionally silent heterochromatin is associated with repetitive DNA

120 Yeast silent heterochromatin provides an excellent model with

121 tio of amino acid changing heterozygosity to silent heterozygosity is higher in dogs than in wolves a

122 Llo is immunologically silent, highly virulent, and lethal.

123 We detected clinically silent hippocampal seizures and epileptiform spikes duri

124 Many parallel fibre synapses might be silent, however, and granule cells in vivo fire in burst

125 High-frequency firing "wakes up" silent Ib synapses and depresses Is synapses.

126 -OX40 antibody with IgG1 Fc but not with the silent IgG2sigma Fc.

127 Although this locus is silent in epithelial cells, and neither NAT transcript n

128 n wherein HIV-1 can remain transcriptionally silent in latently infected CD4+ T cells.

129 ctivated during neuronal differentiation are silent in neural stem cells (NSCs) and occupy black chro

130 ent anti-insulin B cells remain functionally silent in T cell-dependent immune responses, yet these B

131 swimming activity in ambient light but fall silent in the dark.

132 While HK2 often remains silent in the genome, this group of viruses is activated

133 different than plasmids because they reside silent in the host chromosome and are maintained through

134 ults known to have had large earthquakes are silent in the interseismic period is a long-standing eni

135 ity of the genes active in one cell type and silent in the other tend to share demethylated promoters

136 B signal transduction pathway that is nearly silent in V. cholerae of the El Tor biotype.

137 vation (XCI) to generate a transcriptionally silent inactive X chromosome (Xi) enriched with heteroch

138 se invariably fatal brain diseases following silent incubation periods that can span a lifetime.

139 e majority of liver-related PVN neurons were silent, indicating that liver-related PVN neurons are mo

140 tte located in an intergenic region remained silent, indicating that the transgene promoter and/or in

141 yurea [SWiTCH]) or silent cerebral infarcts (Silent Infarct Transfusion [SIT] Trial).

142 due to the paucity of studies on clinically silent infection.

143 rmation in budding yeast is regulated by the silent information regulator (SIR) complex.

144 Silent information regulator 1 (Sirt1) is a histone deac

145 drogen peroxide (H2O2), which down regulated silent information regulator 1 (SIRT1), a class-III hist

146 o study cell proliferation in vivo Mammalian silent information regulator 1 (SIRT1), a NAD(+)-depende

147 rogenase 1 (Gdh1) revealed that it regulates silent information regulator complex recruitment to telo

148 of histone deacetylases (HDACs) 1 and 9, and Silent information regulator genes (sirtuins [SIRTs]) 6

149 nown to recognize AC, and of the deacetylase silent information regulator T1, which had not previousl

150 solated optic nerves, which are electrically silent, is extended by preincubation with NMDA, mimickin

151 had stable or unstable angina or documented silent ischaemia, and a maximum of two de-novo lesions w

152 etes mellitus (DM) have less angina and more silent ischemia when compared with those without DM.

153 cult in diabetics owing to the prevalence of silent ischemia with unrecognized myocardial infarction,

154 ts with DM experience less angina because of silent ischemia.

155 As a "silent killer", kidney disease is often hardly detected

156 Functions for 'silent' L- and T-channels in NAc could be unmasked by el

157 type 1 (HIV-1) establishes transcriptionally silent latent infections in resting memory T cells and h

158 toms occur, aortic stenosis is preceded by a silent, latent phase characterized by a slow progression

159 nsferase genes MET1 or CMT3, erases HISN6B's silent locus identity, reanimating the gene to circumven

160 ressed gene from suppressive influences of a silent locus.

161 -85 mV and has been considered electrically silent, low voltage-activated T-type Ca(2+) channels are

162 2015) now demonstrate that transcriptionally silent mammalian sperm require Wnt signaling via exosome

163 n patients with fCCM and may be a clinically silent manifestation of disease.

164 hCG signaling activates silent mating type information regulation 2 homolog 1 (S

165 as associated with a significant increase in silent mating type information regulation 2 homologue 1

166 KEY POINTS: Silent mating type information regulation 2 homologue 1

167 sion of both telomere-proximal genes and the silent mating type loci, and transcriptional activation

168 Two exceptions are synIII, which lacks the silent mating-type cassettes, and synXII, specifically w

169 ke) and any-CVD (MACE plus confirmed angina, silent MI, revascularization, or congestive heart failur

170 a visualization of an 8-minute symphony as a silent movie and used it as real-time cue for musicians

171 ms) and frequency (1200 Hz) while watching a silent movie.

172 molecular pathological mechanism by which a silent mutation inhibits splicing and leads to intron re

173 dominant genetic disease that is caused by a silent mutation of the LMNA gene encoding lamins A and C

174 We identified a heterozygous silent mutation, c.7464C>T, in exon 44 of the von Willeb

175 Whole-genome sequencing studies revealed a silent mutational landscape, which contradicts the aggre

176 Disease-associated silent mutations are considered to affect the accurate p

177 se strain that expresses HBZ mRNA altered by silent mutations but encoding intact protein.

178 ve broader implications for the relevance of silent mutations in the evolution and fitness of RNA vir

179 efficacy comparable to shRNAs, and introduce silent mutations into an ataxin 7 transgene such that it

180 Missense to silent mutations ratio and the persistence of potentiall

181 de new mechanistic insights into the role of silent mutations selected during antiretroviral therapy

182 ely 2500 generations of PACE contains 20 non-silent mutations, cleaves human IL-23 at the target pept

183 DCK cDNA was created by the introduction of silent mutations.

184 Race and sex differences in silent myocardial infarction (SMI) are not well establis

185 disease, were adjudicated by committee, and silent myocardial infarction was assessed by serial elec

186 hat this live attenuated vaccine acts like a silent natural infection in priming or boosting host imm

187 the invisible, tasteless, odorless, and thus silent nature of arsenic.

188 tributors to GC's high mortality include its silent nature, late clinical presentation, and underlyin

189 s mediated by rapid transitions in 'activity-silent' neural states (for example, short-term synaptic

190 e first report suggestive of presynaptically silent neuromodulatory synapses.

191 model for direction computations, in which "silent" NMDA receptors play critical roles.

192 AP-1 and that recombinant NRAP-1 can convert silent NMDARs to functional channels.

193 Anti-Ro/SSA may represent a clinically silent novel risk factor for TdP development via an auto

194 qRAS-labeled macromolecules are silent (off) inside the intact endocytic organelles, but

195 structural simplicity, fast response speed, silent operation, and low power consumption.

196 osable elements are either transcriptionally silent or active.

197 These so-called silent or cryptic gene clusters are sources of new natur

198 etic modifiers have been of high interest as silent OR genes are decorated with transcriptionally rep

199 ions that render the underlying genes either silent or poised for transcription.

200 Silent or subclinical celiac disease may result in poten

201 onal derepression proportionally greatest in silent or weakly transcribed intergenic and genic region

202 of function from those that are functionally silent, or even contributing to aberrant functions, repr

203 on the use of ASOs to activate the normally silent paternal copy of the imprinted UBE3A gene in neur

204 of the general population, where they may be silent, perhaps reflecting allelic factors.

205 asynchronous state) and (2) "filling-in" of silent periods with low-frequency (2-4 Hz) activity (beg

206 eurons that alternate bursting activity with silent periods, but the mechanism underlying this vital

207 witch to a more invasive and immunologically silent phenotype.

208 fferential expression data can reveal these "silent players".

209 SMN2 harbours a silent point mutation that favours the production of tra

210 to mediate the formation of a minimal yeast silent pre-heterochromatin in vitro.

211 rst-hit mutation that initiates a clinically silent pre-leukemia in utero.

212 biquitous presence of oncogenic mutations in silent premalignancies or the dynamic switching without

213 novel design to show that inner speech - the silent production of words in one's mind - is also assoc

214 Because of its clinically silent progression and lack of symptoms, detection is of

215 e phase of infection and the reactivation of silent proviral DNA in latently infected cells.

216 ription of four so far cryptic and otherwise silent putative SM gene clusters was induced in the KMT6

217 that each displays a single peak in the cell-silent Raman spectral window; when combined with availab

218 at epigenetically activate transcriptionally silent rDNA.

219 RES: MNRead maximum reading speed, sustained-silent reading speed, and comprehension score.

220 ration (AMD) on short out-loud and sustained silent reading speeds, and reading comprehension.

221 reading test was used to evaluate sustained silent reading speeds, while reading comprehension was a

222 reading comprehension was assessed based on silent reading test text.

223 Sustained silent reading test was used to evaluate sustained silen

224 Previously silent recessive defects of the myocardium may predispos

225 that the majority of patients with IPF have silent reflux with no symptoms of GER.

226 nd distinctive Raman vibrations in the Raman-silent region (1800-2800 cm(-1) ) is highly required for

227 ncement effect of alkyne vibrations in Raman-silent region compared to alkyne-containing small molecu

228 The recruitment of Lem2 and Nur1 to silent regions of the genome is dependent on H3K9 methyl

229 that Neanderthal-inherited sequences are not silent remnants of ancient interbreeding but have measur

230 ion occurs when population activity is in a 'silent' response mode in which neurons increase informat

231 hypothesis that anti-Ro/SSA may represent a silent risk factor in patients developing TdP.

232 ed the ability of 3 covert speech paradigms: Silent Sentence Completion (SSC), category naming (CAT)

233 Non-silent sequence alterations were confirmed in 76 cancer-

234 l induction upon mixing two independently CD-silent solutions of the achiral (soldier) and chiral (se

235 tial spine formation by filling functionally silent spines with glutamate receptors.

236 which was triggered after reading the book "Silent Spring" by Rachel Carson.

237 more than fifty years after Rachel Carson's Silent Spring, pesticides, particularly insecticides, ar

238 olycomb group (PcG) proteins to maintain the silent state and Trithorax group (TrxG) proteins to oppo

239 ionally active state marked by H3K36me3 or a silent state marked by H3K27me3.

240 ntain genes required for other lineages in a silent state.

241 cription, is dynamic rather than locked in a silent state.

242 active, reversibly silent, and irreversibly silent states.

243 ed this deficit using principles of receptor silent substitution to present images in which visibilit

244 ore than 95 kb but not the more proximal and silent Sult1e1 gene.

245 now analysed the mechanisms underlying this "silent survival" effect.

246 rats, which was interpreted as evidence of "silent survivor" cells.

247 prevented the enhancement of PA learning and silent synapse formation.

248 ive animal models to examine the role of NAc silent synapse maturation in cocaine-conditioned place p

249 Silent synapse-based NAc remodeling was shown to be crit

250 ocaine-CPP and exhibited increased levels of silent synapses after drug-context conditioning.

251 f small NMDA currents, dynamic unblocking of silent synapses and NMDA-receptor-dependent AP firing.

252 eins exhibit distinct maturation patterns of silent synapses and thus provided instructive animal mod

253 Our results indicate that silent synapses are formed only in neuronal ensembles of

254 After drug withdrawal, cocaine-generated silent synapses became 'unsilenced' by recruiting AMPA r

255 s to the NAc, a portion of cocaine-generated silent synapses becomes unsilenced by recruiting calcium

256 ection in vivo transiently re-silenced these silent synapses by removing CP-AMPARs.

257 signaling in CA3 and/or with an elevation in silent synapses in CA3, a state that may contribute to a

258 Cocaine selectively induced silent synapses in D1-type neurons, likely via a synapto

259 ptogenesis process, whereas morphine induced silent synapses in D2-type neurons via internalization o

260 hese data demonstrate that cNIC can increase silent synapses in MSNs, as observed with cocaine and op

261 ndicate that CP-AMPAR-mediated maturation of silent synapses in the NAc is a signature of drug-contex

262 Exposure to cocaine generates silent synapses in the nucleus accumbens (NAc), whose ev

263 ocaine- and morphine-induced upregulation of silent synapses in the ventral striatum; we show it can

264 Correspondingly, silent synapses in these mice were induced in GFP+ neuro

265 Silent synapses increased in GFP+ neurons, but not in GF

266 hat results from low innervation rather than silent synapses or low release probability.

267 ns (NAc) projection, and maturation of these silent synapses via recruiting calcium-permeable (CP) AM

268 D1-type neurons, whereas morphine-generated silent synapses were likely eliminated to weaken excitat

269 After 45-d withdrawal, silent synapses within this projection returned to the b

270 volved in the evolution of cocaine-generated silent synapses within this projection.

271 t after cocaine withdrawal and maturation of silent synapses, the BLA-to-NAc projection became highly

272 ith a concomitant upregulation of NMDA-only, silent synapses.

273 ithdrawal were associated with generation of silent synapses.

274 elective recruitment of previously active or silent synapses.

275 Whole-cell patch clamp was used to assess silent synapses.

276 ly to arise from low-release-probability or 'silent' synapses that are recruited during longer bursts

277 information in working memory via "activity-silent" synaptic mechanisms.

278 h treatment but the condition will remain a "silent thief of sight" in West Africa unless awareness,

279 ed that two mutations, including a recurrent silent third base change, cause exon skipping.

280 echanism of proteins but has remained mostly silent to protonation changes in the aqueous medium.

281 %) formally transferred out, 987 (2.5%) were silent transfers and visited another Western Cape provin

282 Structural barriers contribute most to silent transfers, whereas psychological and social barri

283 e, Hyderabad, Sukkur, and Jacobabad revealed silent transmission and the need for vigilant surveillan

284 The receptor is an optically silent uncharged ionophore selective for the analyte cat

285 ed, leaving the majority of SM gene clusters silent under laboratory conditions.

286 econdary metabolite synthesis are presumably silent under standard laboratory condition.

287 of pioneer transcription factors in engaging silent, unmarked chromatin and activating hierarchical g

288 ors' are dominant in their ability to engage silent, unmarked chromatin and initiate the recruitment

289 As G6PD deficiency can be clinically silent until illness strikes, we recommend investigation

290 cell zone of lymph nodes responsible for the silent uptake of vast numbers of apoptotic cells.

291 se lncRNAs in trans triggers activation of a silent var gene in a sequence- and dose-dependent manner

292 d families by 18- to 210-fold, including the silent virulence factor malleilactone.

293 When ON RGCs were rendered silent while enhancing the firing rate of OFF RGCs, c-Fo

294 and may serve to provide an immunologically-silent window by generating specific "find me" and "eat

295 ficient for classifying neurons as active or silent with high accuracy.

296 Ser, Thr, Asp, and Glu, which are relatively silent with regard to (.) OH.

297 as hippocampal engram cells gradually became silent with time, engram cells in the basolateral amygda

298 ctivation that encodes an RNA that coats the silent X chromosome, and modulation of regulators of thi

299 In replicating nuclei from transcriptionally silent Xenopus egg extracts, we identified numerous acti

300 promoter of a gene is presumed to render it silent, yet a sizable fraction of genes with methylated