ライフサイエンスコーパス: silylated

1 ortho-substituted aryl halides failed to be silylated.

2 t facile cyclization/hydrosilylation to form silylated 1,2-dialkylidene cyclopentanes as mixtures of

3 The silylated 1,2-dialkylidenecyclopentanes formed via diyne

4 sequence provides both synthetically useful silylated 1,3-diene building blocks and insights into th

5 s, and provides very high yields of the beta-silylated 1,4-addition products.

6 ctive glycosylation of protected ribose with silylated 4(5)-haloimidazoles produces 5-haloimidazole r

7 entose sugar derivatives were condensed with silylated 4-amino-5-oxopyrido[2,3-d]pyrimidine, followed

8 Silylated 4-aminopyrimidines 2 or 5 upon ribosylation wi

9 talyzed coupling of glycosyl phosphates with silylated acceptors is also discussed.

10 n can be used to fine-tune the reactivity of silylated/acetylated sugar building blocks.

11 Addition of a silylated acetylide to 11 in diethyl ether/trimethylamin

12 (5) to chiral ketocyclopentenes 6 to provide silylated adducts 9 or alcohol derivatives 10 and 11.

13 the gem-difluoroalkyl radical generated from silylated adducts 9 or alcohols 10 and 11 afforded gem-d

14 iety by phosphine provided the corresponding silylated alcohols in useful yields.

15 at it is the more substituted benzylidene or silylated alkylidenes that are involved in the catalytic

16 is identical to that of the CM reactions of silylated alkynes and alkenes.

17 oselective cross metathesis reaction between silylated alkynes and terminal alkenes.

18 rst examples of the sigma-bond metathesis of silylated alkynes with aromatic carboxylic acids on the

19 In contrast, silylated allenes favor the formation of propargylic cat

20 cationic intermediates from nonsilylated and silylated allenes is strongly supported by DFT calculati

21 Several C-silylated (allyldimethylsilyl) calixarenes (1, 14, and 1

22 Esters of three types of silylated alpha-amino acids have been prepared from appr

23 commercial silica nanoparticles (SN) via the silylated amine and glutaric dialdehyde links.

24 dride that subsequently reacts to yield an N-silylated amine and the borane catalyst.

25 The silylated amino acid (l)-(trimethylsilyl)alanine (TMSAla

26 The silylated and fluorinated products were obtained as sing

27 They were silylated and subjected to a Perkow reaction with ethyl

28 rostanes were prepared and purified by HPLC, silylated, and then analyzed by gas chromatography (GC)

29 Taxol C and paclitaxel were sequentially silylated at the 2', 7, and 1-hydroxyl groups with tert-

30 es an activated dinitrogen unit which can be silylated at the beta-nitrogen atom.

31 Our previously proposed, silylated beta-lactone intermediate that led to successf

32 r procedure was employed in the synthesis of silylated bicyclopentanes and a linear triquinane.

33 rbynes undergo C-C bond formation, releasing silylated C2O1 fragments and demonstrating that the mult

34 in DME gave a mixture of tetrakis- and tris-silylated calixarenes (6 and 7).

35 s C for 48 h to form an 8.1:1 mixture of the silylated carbocycle (S,S)-trans-1, 1-dicarbomethoxy-4-m

36 Silylated carbocycles generated from benzhydryldimethyls

37 The NMR study indicates that the silylated carbonyl compounds are resonance hybrids of ox

38 A series of silylated carboxonium ions, 2a-6a, were prepared as long

39 igands that were generated starting out from silylated chalcogenide sources.

40 onyl chloride, using a catalytic amount of a silylated cinchona alkaloid as a source of chirality.

41 However, the reaction with the bis-silylated cluster [Ge9{Si(TMS)3}2](2)(-) yields the nove

42 y) or isopropyl- ((i)Pr) groups and the tris-silylated cluster [Ge9{Si(TMS)3}3](-) yield the novel ne

43 Reactions of silylated clusters [Ge9{Si(TMS)3}3](-) or [Ge9{Si(TMS)3}

44 vity of the dialkylhalophosphines toward the silylated clusters is observed depending on the bulkines

45 ins with a rather random distribution of the silylated comonomer when m-DMSS is used, but to chains w

46 g a direct access to synthetically versatile silylated compounds.

47 Silylated cyclopentanes derived from HSiMe(2)OSiMe(3) we

48 Silylated cyclopentanes derived from HSiMe(2)OSiPh(2)t-B

49 (6)H(3)(CF(3))(2)] to form the corresponding silylated cyclopentanes in good yield with high diastere

50 transition-metal-catalyzed rearrangement of silylated cyclopropenes to the corresponding allenes is

51 tion reaction between p-nitroanisole and a C-silylated derivative of N-methylpyrrolidinone.

52 laced within the silica framework by using a silylated derivative of the well-known tris(bipyridine)r

53 xes, [M (VI)O 3- n S n (bdt)] (2-) and their silylated derivatives [M (VI)O 2- n S n (OSiR 3)(bdt)] (

54 The I(T) retention indices of silylated derivatives of 449 substances registered in th

55 diequatorial chair equilibrium in a range of silylated derivatives of trans-1,4- and trans-1,2-dihydr

56 Silylated derivatives retain carbon with the silicon and

57 ration of uracil and thymine by way of their silylated derivatives under catalysis with stannic chlor

58 enough to pass through a gas chromatograph, silylated derivatization reactions are commonly used to

59 reactions of a series of silyloxydienes and silylated dienes with acyclic alpha,beta-unsaturated ket

60 ed-(benzylated), or the classic super armed (silylated) donors.

61 mounts of the corresponding free amine and N-silylated enamine are present in equimolar ratio during

62 yed to show that the alcohol stereocenter of silylated, enantiopure secondary alcohols can transmit c

63 Their reactions with pi-nucleophiles 8(a-j) (silylated enol ethers and ketene acetals) were studied k

64 s similar to those of pyrroles, indoles, and silylated enol ethers and, therefore, should be suitable

65 are derived from S(N)2-like reactions of the silylated epoxide with the diene, in which stereospecifi

66 tautomerization and elaboration of R to give silylated furanonaphthols 4 bearing an aldehyde side cha

67 ethyl-1,4-hydroquinone diacetate (16) formed silylated fused bicyclic complexes in good yield.

68 on of tert-butoxide from silicon lead to the silylated heteroarene product.

69 terocycles enables the synthesis of valuable silylated heteroarenes.

70 trichloride mediated cyclization reaction of silylated homoallylic alcohols, thiols, or amines with a

71 diiodide along with the N,N'-dicarboxylated silylated hydrazine.

72 ions of silylated hydroperoxyacetals furnish silylated hydroperoxides, which can be deprotected to ho

73 Lewis acid-promoted reactions of silylated hydroperoxyacetals furnish silylated hydropero

74 ng salt metathesis reactions to alkylated or silylated imidazolinium derivatives, (L(E))ScR(3) (E = S

75 A novel silylated imine was designed to act efficiently in a che

76 o activate with precious metal catalysts are silylated in good yield and with excellent regioselectiv

77 but a (hydroxymethyl)boronic ester has been silylated in the usual manner.

78 Free hydroxyl groups were subsequently silylated in-port.

79 s oxygen analogue have been synthesized from silylated internal alkyne using Larock's heteroannulatio

80 iminium ions with C-nucleophiles (enamines, silylated ketene acetals, and enol ethers) have been det

81 A silylated ligand that binds lanthanides condenses to for

82 d conditions by employing ring expansions of silylated methyleneaziridines.

83 Alkylation of O-silylated N-alkylmalonylhydroxamic acids provides a meth

84 Here, we assessed the ability of these new silylated NT compounds to bind to NTS1 and NTS2 receptor

85 al and theoretical study that elucidates why silylated nucleobase additions to acyclic alpha-alkoxyth

86 In the presence of an in situ silylated nucleobase, thioglycosides can be activated wi

87 ained diastereoselectively from additions of silylated nucleobases onto acyclic polyalkoxyaldehydes i

88 The addition of silylated nucleobases onto model C2-fluorinated dithioac

89 Likewise, silylated nucleophiles such as trimethylsilylazide, ally

90 zed to enhance the reaction scope and enable silylated nucleophiles to be efficiently exploited to sy

91 ere successfully functionalized with various silylated nucleophiles without epimerization of the ster

92 honate approach involves a key intermediate, silylated nucleoside amino acid phosphoramidite 6, prepa

93 We report herein a 5'-silylated nucleoside scaffold derived from 3'-azidothymi

94 a a novel three-step procedure starting from silylated polystyrene is reported.

95 rocarboxylic acid (HMDS and PFCA), the fully silylated PPAAs offer several advantages.

96 urinary matrix by solid-phase extraction and silylated prior to quantification.

97 as also accomplished by carbonylation of the silylated product, yielding an unprecedented mu-formamid

98 omofuran, and 2-bromopyridine failed to give silylated product.

99 e addition of 1,3-propane dithiol to various silylated propargylic aldehydes and ketones allows for a

100 The acetate 7 was condensed with silylated purine and pyrimidine bases, which produced th

101 Chiral silylated pyrrolidine catalysts are obtained in high yie

102 A Wittig reaction on a per-O-silylated rather than per-O-acetylated or -benzylated su

103 tion of indenyl substituent and demonstrates silylated sandwiches favor THF coordination and the eta(

104 t attachment of photoactivatable biotin onto silylated silicon wafers.

105 hroline; Ar = 3,5-C(6)H(3)(CF(3))(2)] formed silylated spirocycles in high yield with excellent regio

106 or some monosilyloxycyclohexanes and in some silylated sugars.

107 In a similar way, N-alkylated and N-silylated tert-butyl carbamates were used for the synthe

108 mediate along the proposed reaction pathway, silylated thiazolium carbinols have been identified to p

109 l-phase HPLC separation, the isotopomers are silylated to their tBDMS derivatives.

110 ains with tapered block structures, with the silylated units near the initiator, when p-DMSS is used.

111 oxathiolane and dioxolane intermediates with silylated uracil analogues using TMSI as the coupling ag

112 o-2-deoxy-2-fluoro sugars with corresponding silylated uracil derivatives.

113 acetate 8 with the appropriate heterocycles (silylated uracil, thymine, N4-benzoylcytosine, N4-benzoy

114 Switching on uranium(V) reactivity: The silylated uranium(V) dioxo complex [(Me(3)SiOUO)(2)(L)(2

115 Aryllithium species were silylated using 1.5 equiv of tetraethyl- or tetramethyl

116 ethod was developed whereby morphine was bis-silylated using normal conditions followed by selective

117 cohols bearing a Z-iodoalkenyl tether can be silylated with chlorodimethylvinylsilane and subjected t