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1 erologous prime-boost with the viral vectors simian adenovirus 63 (ChAd63)-modified vaccinia virus An
3 l swarm and allowed to naturally progress to simian AIDS and potential SIV-associated encephalitis (S
6 mentalization was diminished in animals with simian AIDS, which often have low-frequency CTL response
9 r ribosomes and associated mRNAs from human, simian and mice cellular extracts, but did not selective
12 ured mammalian cells, worms, flies, rodents, simians, apes, and even humans, all indicate declining a
13 iviruses (family Flaviviridae) and two novel simian arteriviruses (family Arteriviridae) in wild Afri
15 the phylogenetic and geographic range of the simian arteriviruses and define baboons as a natural hos
18 t in addition to SIV, simian pegiviruses and simian arteriviruses are widespread and prevalent among
20 en together, these features suggest that the simian arteriviruses may be "preemergent" zoonotic patho
21 the genetic and geographic diversity of the simian arteriviruses, identify baboons as a natural host
22 suggests that one of these virus types, the simian arteriviruses, may have the potential to jump bet
24 t hepatocyte cultures through the use of the simian CD81 ortholog as a coreceptor, indicating that HC
31 specimens were not reliable for detection of simian disease carriers before onset of clinical signs.
33 in global redistribution of PFV and macaque simian foamy virus (SFVmac) integration sites toward cen
38 have played a role in previous outbreaks of simian hemorrhagic fever in macaques, as has long been s
42 entally infected crab-eating macaques, while simian hemorrhagic fever virus (SHFV) causes lethal vira
44 es and then crab-eating macaques with either simian hemorrhagic fever virus (SHFV) or Kibale red colo
46 used by different strains of the same virus, simian hemorrhagic fever virus (SHFV; Arteriviridae).
47 Close relatives of these viruses, including simian hemorrhagic fever virus, have caused sporadic out
48 t HCV sequences designed to allow entry into simian hepatocytes failed to induce viremia in tamarins
49 cessfully complete its life cycle in primary simian hepatocytes, suggesting the possibility of adapti
50 nv proteins of simian immunodeficiency virus/simian HIV (SIV/SHIV) stock and T/F variants in search o
51 red with those infected with less pathogenic simian HIV, vaccinated and SIVmac-challenged, or SIVmac-
52 hen administered by injection that prevented simian-HIV infection upon repeat intrarectal challenge i
53 cutive low-dose intravaginal challenges with simian-HIV strain SF162P3, with more animals infected co
54 (and may have increased susceptibility to a simian-HIV vaginal challenge), while the microbicide red
56 a primary HIV-1 isolate (HIV-1JR-FL), and a simian-human immunodeficiency virus (SHIV) adapted for p
57 opment of a panel of mucosally transmissible simian-human immunodeficiency virus (SHIV) challenge sto
58 pentavalent-vaccine-immunized macaques from simian-human immunodeficiency virus (SHIV) challenge.
59 s (bNAbs) can protect rhesus monkeys against simian-human immunodeficiency virus (SHIV) challenge.
60 a proportion of CD4(+) T cells resistant to simian-human immunodeficiency virus (SHIV) entry were ch
61 Vh-LS-F potently inhibited in vivo HIV-1 and simian-human immunodeficiency virus (SHIV) infection in
62 ain) elicits heterologous protection against simian-human immunodeficiency virus (SHIV) or simian imm
63 broadly neutralizing MAbs to suppress acute simian-human immunodeficiency virus (SHIV) replication i
64 as they incompletely neutralize the clade C simian-human immunodeficiency virus (SHIV) stock (SHIV-3
65 ith pig-tailed macaques demonstrated various simian-human immunodeficiency virus (SHIV) susceptibilit
66 imary isolates in vitro and protects against simian-human immunodeficiency virus (SHIV) when delivere
67 h reduced infection rates in studies of HIV, simian-human immunodeficiency virus (SHIV), and simian i
68 m 16 simian immunodeficiency virus (SIV)- or simian-human immunodeficiency virus (SHIV)-infected and
69 ion, simian immunodeficiency virus (SIV)- or simian-human immunodeficiency virus (SHIV)-infected nonh
70 between neutralizing antibodies elicited by simian-human immunodeficiency virus (SHIV)-infected rhes
71 ed V3-glycan antibody PGT121, in chronically simian-human immunodeficiency virus (SHIV)-SF162P3-infec
72 ave shown that simian immunodeficiency virus/simian-human immunodeficiency virus (SIV/SHIV) exposure
73 5-tropic strains SIVmac239, SIVsmE543-3, and simian-human immunodeficiency virus SHIV-AD8 in RM PBMC.
74 matical models in conjunction with data from simian-human immunodeficiency virus SHIV89.6P infection
76 d raises a cautionary note for SIV and SHIV (simian-human immunodeficiency virus) vaccine studies tha
77 of the ICs targeted with 7B2 in mice and in simian-human immunodeficiency virus-infected macaques.
79 cell loss in vivo, we infected macaques with simian-human immunodeficiency viruses (SHIV) and followe
81 erred complete immunity against a mixture of simian-human immunodeficiency viruses (SHIVs) in nonhuma
82 coded" challenge viruses and next-generation simian-human immunodeficiency viruses that may advance t
83 nst a single high-dose challenge with HIV or simian/human (SIV/HIV) chimaeric viruses (SHIVs) respect
84 of TAF and emtricitabine (FTC) could prevent simian/human immunodeficiency virus (SHIV) infection in
85 t early administration of bNAbs in a macaque simian/human immunodeficiency virus (SHIV) model is asso
87 nterruption data from macaques infected with simian/human immunodeficiency virus (SHIV), we observe a
88 (8-15 y) and old (>20 y) RM with recombinant simian IL-7 (rsIL-7) results in only transient increases
90 s that were molecularly engineered with anti-simian immunodeficiency virus (anti-SIV) activity into r
91 Chronic human immunodeficiency virus and simian immunodeficiency virus (HIV and SIV) infections a
93 d rhesus macaques infected with the human or simian immunodeficiency virus (HIV or SIV), respectively
94 thway in human immunodeficiency virus type 1/simian immunodeficiency virus (HIV-1/SIV) infection rema
96 ence of a distinct subpopulation of human or simian immunodeficiency virus (HIV/SIV) sequences within
98 imian-human immunodeficiency virus (SHIV) or simian immunodeficiency virus (SIV) acquisition in three
99 ine-induced antibodies to capture infectious simian immunodeficiency virus (SIV) and explored the rel
101 nodes from pigtailed macaques infected with simian immunodeficiency virus (SIV) carrying HIV-1 rever
102 e that showed significant protection against simian immunodeficiency virus (SIV) challenge and sugges
104 cytes (CD8TL) are associated with control of simian immunodeficiency virus (SIV) despite extensive ne
105 se macaques consistently displayed low-level simian immunodeficiency virus (SIV) diversity, which was
106 ls (DCs) and B cells, as an adjuvant for our simian immunodeficiency virus (SIV) DNA vaccine in rhesu
107 mmunization, or the capacity to neutralize a simian immunodeficiency virus (SIV) Env-expressing pseud
108 human immunodeficiency virus type 1 (HIV-1)/simian immunodeficiency virus (SIV) envelope spike (Env)
109 ural-host sooty mangabeys (SM) infected with simian immunodeficiency virus (SIV) exhibit high viral l
110 nt study, we found that protection following simian immunodeficiency virus (SIV) exposure correlated
111 TANCE Human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) express a small prot
112 lymorphism limits and complicates the use of simian immunodeficiency virus (SIV) for evaluation of hu
114 ycobacterium tuberculosis strains expressing simian immunodeficiency virus (SIV) genes safely induces
115 an immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIV) gp120 exterior envel
116 ons.IMPORTANCE Rhesus macaque infection with simian immunodeficiency virus (SIV) has served as an imp
117 ts of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) have been described
119 -1)-infected humans, African-origin, natural simian immunodeficiency virus (SIV) hosts, such as Afric
120 n immunodeficiency virus (HIV) in humans and simian immunodeficiency virus (SIV) in macaques (MAC) le
121 on of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) in vivo is well esta
122 GI) tract of Asian macaques with progressive simian immunodeficiency virus (SIV) infection and humans
123 erable to human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) infection and thus a
126 ght contribute to the asymptomatic nature of simian immunodeficiency virus (SIV) infection in its nat
127 re changes in mucosal IL-10 signaling during simian immunodeficiency virus (SIV) infection in rhesus
128 n genes that show a response to experimental simian immunodeficiency virus (SIV) infection in vervet
130 re we studied progressive and nonprogressive simian immunodeficiency virus (SIV) infection models in
131 age proliferation occurs in the brain during simian immunodeficiency virus (SIV) infection of adult m
134 n pathways involved in establishing systemic simian immunodeficiency virus (SIV) infection, we necrop
140 A subtype C isolate was similar, while a simian immunodeficiency virus (SIV) isolate showed signi
143 ) lymphocyte-depleted macaques infected with simian immunodeficiency virus (SIV) provide an increasin
144 is of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) reflects a balance b
147 ions, human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) replication may cont
148 We developed a method to capture total-body simian immunodeficiency virus (SIV) replication using im
150 d in all primate lentiviruses, and its HIV-2/simian immunodeficiency virus (SIV) SIVsm paralogue Vpx,
154 abeys (SM) are well-studied natural hosts of simian immunodeficiency virus (SIV) that do not progress
155 g in rhesus macaques (Macaca mulatta) during simian immunodeficiency virus (SIV) transmission and acu
156 ted DNA/modified vaccinia virus Ankara (MVA) simian immunodeficiency virus (SIV) vaccine enhances pro
157 alization sieve effect in a nonhuman primate simian immunodeficiency virus (SIV) vaccine trial (DNA p
159 o evaluate antibody specificities induced by simian immunodeficiency virus (SIV) versus human immunod
161 20 of human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) was investigated for
162 (HIV) emergence following human exposures to simian immunodeficiency virus (SIV), an understanding of
163 sory proteins of primate lentiviruses HIV-1, simian immunodeficiency virus (SIV), and BIV all form ub
164 can green monkeys (AGM) are natural hosts of simian immunodeficiency virus (SIV), and infection in th
165 quely valuable for genetic investigations of simian immunodeficiency virus (SIV), for which it is the
166 sum A1 partially inhibited HIV-1, as well as simian immunodeficiency virus (SIV), murine leukemia vir
167 nhuman primates were coinfected with Mtb and simian immunodeficiency virus (SIV), recapitulating huma
169 orescence microscopy thoracic aortas from 16 simian immunodeficiency virus (SIV)- or simian-human imm
171 ere validated in archival brain tissues from Simian Immunodeficiency Virus (SIV)-infected and uninfec
172 irus-specific cell-mediated immunity in both simian immunodeficiency virus (SIV)-infected and uninfec
173 ts were detectable, but increased 20-fold in simian immunodeficiency virus (SIV)-infected animals.
174 ejuna, and livers of healthy and chronically simian immunodeficiency virus (SIV)-infected Asian macaq
175 iciency virus (HIV)-infected individuals and simian immunodeficiency virus (SIV)-infected Asian macaq
176 fected monocytes and macrophages to HIV- and simian immunodeficiency virus (SIV)-infected cells in vi
177 re loss of lean body mass and body weight in simian immunodeficiency virus (SIV)-infected juvenile rh
180 body-mediated CD8(+) lymphocyte depletion in simian immunodeficiency virus (SIV)-infected rhesus maca
181 s system (CNS) has not yet been reached, the simian immunodeficiency virus (SIV)-infected rhesus maca
183 dictates the tempo of progression to AIDS in simian immunodeficiency virus (SIV)-infected rhesus maca
186 cells or purified CD4(+) T cells from HIV or simian immunodeficiency virus (SIV)-infected subjects wi
190 Human immunodeficiency virus (HIV)- and simian immunodeficiency virus (SIV)-specific CD8(+) T ce
202 al, nasal, and vaginal vaccinations with DNA simian immunodeficiency virus (SIV)/interleukin-2 (IL-2)
205 e detected in the blood of Gambian primates: simian immunodeficiency virus (SIVagm; in 42% of animals
206 etherin, is associated with the evolution of simian immunodeficiency virus (SIVcpz) into pandemic gro
207 re targeted by primate lentiviruses (HIV and simian immunodeficiency virus [SIV]) are of intense inte
208 an immunodeficiency virus type 1 [HIV-1] and simian immunodeficiency virus [SIV]) if its activity is
211 enhanced by substituting naturally occurring simian immunodeficiency virus Env residues at position 3
212 the result of cross-species transmission of simian immunodeficiency virus from chimpanzees (SIVcpz).
213 evant rhesus macaque model of infection with simian immunodeficiency virus from sooty mangabey (SIVsm
214 by electroporation (DNA/EP), all expressing Simian immunodeficiency virus group specific antigen/tra
215 the gut is well-maintained in nonpathogenic simian immunodeficiency virus infection as well as HIV-1
216 ontaining protein 1 (SAMHD1) restricts human/simian immunodeficiency virus infection in certain cell
217 tection from human immunodeficiency virus or simian immunodeficiency virus infection remain incomplet
220 agrees well with the experimental data from simian immunodeficiency virus infections in morphine-add
221 ng limiting-dose inoculations with a diverse simian immunodeficiency virus isolate stock may increase
222 of neutralization-resistant HIV-1, HIV-2 and simian immunodeficiency virus isolates, including a comp
223 ctious molecular clones from two widely used simian immunodeficiency virus lineages (SIVmac251 and SI
224 an immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus mac239 (SIV(mac239)) repli
226 l reservoir during infections with HIV-1 and simian immunodeficiency virus of macaques (SIVmac).
227 degradation and inhibited wild-type SIVmac (simian immunodeficiency virus of macaques) infection of
228 iral protein X (Vpx) proteins from the major simian immunodeficiency virus of rhesus macaque, sooty m
230 NK cell activity in cells infected with HIV, simian immunodeficiency virus, and other persistent viru
231 ue lungs by DeltasigH was not reactivated by simian immunodeficiency virus, despite high viral levels
232 s among uninfected animals exposed to HIV or simian immunodeficiency virus, irrespective of route of
235 We therefore used antifibrotic therapy in simian immunodeficiency virus-infected rhesus macaques t
238 emained at protective levels despite chronic simian immunodeficiency virus/HIV-induced immunosuppress
239 the differences between the Env proteins of simian immunodeficiency virus/simian HIV (SIV/SHIV) stoc
240 ugh nonhuman primate studies have shown that simian immunodeficiency virus/simian-human immunodeficie
244 ependent cross-species transmission event of simian immunodeficiency viruses (SIVs) infecting African
246 er lentiviruses, including HIV-2 and related simian immunodeficiency viruses (SIVs), SAMHD1 restricti
247 en widely accepted to be the consequences of simian immunodeficiency viruses from wild chimpanzees (S
249 h Nef is the viral gene product used by most simian immunodeficiency viruses to overcome restriction
253 y virus (SIVagm; in 42% of animals), a novel simian pegivirus (SPgVagm; in 7% of animals), and numero
254 discovery and characterization of two novel simian pegiviruses (family Flaviviridae) and two novel s
255 overies demonstrate that in addition to SIV, simian pegiviruses and simian arteriviruses are widespre
257 om HIV type 1 (HIV-1) and its vpu-containing simian precursors, may promote a selective preservation
258 o ventral premotor areas identified in other simian primates, and that area 8C corresponds to a speci
260 embrane protein called C18 in mobilizing the simian PyV SV40, a PyV archetype, from the ER into the c
265 ted with the NSP1 gene and was observed in a simian SA11 monoreassortant that encoded porcine OSU NSP
266 icance of the B cell dysfunction observed in simian (SIV) and human immunodeficiency virus (HIV) infe
267 he immunodeficiency viruses, human (HIV) and simian (SIV); however, virus rebounds soon after ART is
269 re we provide fundamental information on the simian T lymphotropic virus (STLV) naturally transmitted
270 ype D strain that was closely related to the simian T lymphotropic virus (STLV-1) that infects this m
272 he CD8(+) and CD4(+) T cell response against simian T-lymphotropic virus type 1 (STLV-1), a virus clo
273 e gene encoding a full-length protein in all simians under purifying selection and with similar shedd
278 ronchial inoculation of rhesus macaques with simian varicella virus (SVV) recapitulates the hallmarks
280 al inoculation of rhesus macaques (RMs) with simian varicella virus (SVV), a homolog of VZV, recapitu
283 eplicated efficiently and remained stable in simian Vero cells, which do not express these miRNAs, ho
285 The nonenveloped simian polyomavirus (PyV) simian virus 40 (SV40) hijacks the endoplasmic reticulum
287 wever, the MWPyV LT was less stable than the simian virus 40 (SV40) LT and was unable to promote the
288 says, we have found that E7 can provide some simian virus 40 (SV40) or murine polyomavirus (PyV) ST f
289 M also suppressed the constitutively active simian virus 40 (SV40) promoter and globally decreased c
290 her defined oncogenic alleles, including the simian virus 40 (SV40) T antigen (TAg) and oncogenic H-R
291 re cultured in cell lines immortalized using simian virus 40 (SV40) T antigen, suggesting the possibi
292 defined oncogenic alleles, specifically the simian virus 40 (SV40) T antigens and oncogenic Ras(12V)
293 igenesis induced by transgenic expression of simian virus 40 (SV40) TAg in choroid plexus or intestin
295 operties of nonhuman polyomaviruses, such as simian virus 40 (SV40), but is not required for MCV sT-i
296 -associated polyomaviruses (PyVs), including simian virus 40 (SV40), murine PyV, and Merkel cell PyV,
297 In the case of the nonenveloped polyomavirus simian virus 40 (SV40), the virus penetrates the endopla
299 interactions of a whole nonenveloped virus (simian virus 40), as well as those of the hepatitis delt
300 llows it to be recognized by Vpx proteins of simian viruses infecting those primate species, which no
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