ライフサイエンスコーパス: simplify

1 ermine whether the suggested criteria can be simplified.

2 ication of eligible patients for studies was simplified.

3 cated and diverse literature procedures were simplified.

4 To simplify (13)C-MFA of different prokaryotic species, the

5 eting stabilizes heat-sensitive reagents and simplifies a broad range of assays, including isothermal

6 structure into interconnected subpopulations simplified access to the locations of interest.

7 To simplify access to and use of biomolecular NMR software,

8 By simplifying access to metabolite data, we hope that this

9 ng 540 patients (379 men; age, 65 +/- 13 yr; Simplified Acute Physiological Score II, 59 +/- 18; Sequ

10 We used a recalibrated Simplified Acute Physiology 3 model and examined model p

11 nd impact of missing physiologic data on the Simplified Acute Physiology 3 model's performance.

12 The Simplified Acute Physiology 3 outcome prediction model h

13 ity hospital admission, comorbidity, and low Simplified Acute Physiology Score 3.

14 ded in the analysis (48.5 [37-56] years old, simplified acute physiology score II 37 [32-47]) who und

15 ure Assessment score was 8 (4-12) and median Simplified Acute Physiology Score II 49.5 (27-70).

16 n Emergency Department Sepsis score of 0.92, Simplified Acute Physiology Score II and Acute Physiolog

17 acute respiratory distress syndrome, higher simplified acute physiology score II, diagnosis of venti

18 nsumption, respiratory and hemodynamic data, Simplified Acute Physiology Score II, Sepsis-related Org

19 Physiology and Chronic Health Evaluation II, Simplified Acute Physiology Score II, Sequential Organ F

20 Physiology and Chronic Health Evaluation II, Simplified Acute Physiology Score II, Sequential Organ F

21 Median simplified acute physiology score-II (SAPS-II) was 26.

22 ance therapy for childhood ALL should aim to simplify administration.

23 Suicidality) and for anxiety and mood (SASS, Simplified Affective State Scale)) by themselves, as wel

24 iral discovery, PaVE offers a typing tool; a simplified algorithm to determine whether a newly sequen

25 aluation of a rationally designed library of simplified analogs that unveiled three unique biofilm ph

26 liquid chromatography (LC), both in terms of simplifying analysis as well as providing novel selectiv

27 th a level gaze, visual processing tasks are simplified and behaviorally relevant features from the v

28 bed with the polymer microarray for a highly simplified and integrated magnetic bead-based DNA analyz

29 for various processes, but are often highly simplified and may not include an adequate representatio

30 Simplified and more efficient mechanisms to undertake R&

31 derstudied cyclostomes have been revealed as simplified and specialised.

32 and explores the use of extents as a way to simplify and streamline the dynamic process modeling tas

33 correlation with their blood glucose levels, simplifying and reducing the costs of the analyses, maki

34 Simplifying and speeding up the process would be very be

35 High-quality, simplified, and low-cost human immunodeficiency virus (H

36 n age and education adjusting procedure, the simplified ANT1 (S-ANT1 ) was obtained.

37 INTERPRETATION: Two simplified antibiotic regimens requiring fewer injection

38 We aimed to assess the equivalence of two simplified antibiotic regimens, comprising fewer injecti

39 We undertook the Simplified Antibiotic Therapy Trial (SATT), a three-arm,

40 Furthermore, simplified approaches using DVR (t* = 55 min) and static

41 It is argued that the use of simplified approaches without proper validation not only

42 inear distance between locations, making the simplifying assumption that distance decay is isotropic.

43 However, the LCT makes the simplifying assumption that only one individual is sampl

44 0% with theoretical predictions based on the simplifying assumption that the slurry consists of unifo

45 development, but existing applications make simplifying assumptions that often break up the dependen

46 ur additional models were developed based on simplifying assumptions, and all five models were tested

47 mpirical data violate several of the model's simplifying assumptions.

48 The model contains simplified behaviors to capture the extremes of possible

49 integration has used artificial stimuli and simplified behaviors, leaving open questions about nervo

50 Social integration was assessed by a simplified Berkman-Syme Social Network Index every 4 yea

51 The simplified binary labelling and classification of sexual

52 this analysis we used a spatially explicit, simplified bottom-up approach, based on animal inventori

53 mmable DNA targeting and editing platform is simplified by a synthetic single-guide RNA (sgRNA) mimic

54 The nonlocal kernel is simplified by limiting the nonlocal atomic interaction i

55 Downstream interpretation is greatly simplified by preprocessing such a dataset as follows: (

56 While diagnosis of acute VL has been simplified by the use of cost-effective confirmatory ser

57 te factorizations of the likelihood function simplify calculations at the expense of discarding certa

58 method, we used bioluminescent E. coli in a simplified checkerboard assay to generate unique drug in

59 que that replaces immunoprecipitation with a simplified chromatin fragmentation and proximity ligatio

60 The geometry of the claw used here is a simplified claw model, based on prior experimental work.

61 vances in E. coli self-assembly have greatly simplified cloning, these have not yet been harnessed fo

62 Here, we demonstrate a promising simplified coherent receiver exhibiting a robust perform

63 sed modeling, but are likely to trend toward simplified community composition as communities graduall

64 Our development simplifies complicated assays and the transportation of

65 termine the effects on pseudo-ash samples of simplified composition.

66 Finally, a simplified COMSOL model of the ICE electric field was us

67 general research use (GRU) studies through a simplified controlled-access process.

68 ed palatability, reduced metabolic toxicity, simplified cotreatment for tuberculosis, and preservatio

69 A simplified coupling of surface plasmon resonance (SPR) i

70 However, there are concerns that more simplified cropland with lower crop diversity, less nonc

71 cancer genomics data, most biologists prefer simplified, curated pathway diagrams, such as those feat

72 This new application simplifies data exploration, visualization, and integrat

73 in these and other datasets how the software simplifies data representation, statistical analysis, an

74 A simplified DBS extraction technique for cell-free virus

75 mathematical tractability, these models use simplified descriptions of key patterns, processes and r

76 ed tris(hydroxypyridinone) (THP)-PSMA, has a simplified design for single-step kit-based radiolabelin

77 h 18- to 23-month-olds (Experiment 2), and a simplified design with 12- to 17-month-olds (Experiment

78 in tumors.Significance: A new imaging method simplifies diagnosis and informs decision making during

79 The effort to simplify diagnosis could be overcome by the risk of undi

80 Simplified diagnostic algorithms and treatment regimens

81 ugh nulling of venous contamination, thereby simplifying diagnostic interpretation and communication

82 ps with a high loading were summed to form a simplified dietary pattern score.

83 tiles of the ED, HF, and LFD pattern and the simplified dietary pattern scores was associated with in

84 adians with the use of a priori, hybrid, and simplified dietary pattern techniques, and to compare th

85 A simplified discriminant analysis based on 3 common clini

86 The model simplifies each receptor and each binding site in a mult

87 ur new fragment-based pentamer algorithm and simplified energy function improve both efficiency and a

88 s while including G-U wobble pairs or employ simplified energy models, we present a novel approach us

89 ntegrating this single-molecule cycle into a simplified ensemble description, we predict that the ave

90 pollutant impacts on biota in a controlled, simplified environment.

91 cal predictions utilized generalization of a simplified equilibrium equation.

92 bined with the use of unpurified strands and simplified experimental procedures, for creating a compl

93 ipids, continuous monitoring of transfer and simplified experimental procedures.

94 4 positively regulates KCNQ2/3 channels in a simplified expression system.

95 atric ARVs and suggest innovations to enable simplified, faster, and more comprehensive strategies to

96 These conditions were then simplified for the case of a Leidenfrost drop.

97 A simplified formulation, packaging, and delivery method t

98 bacteria and designed DNA (or potentially a simplified genome) to instruct the cell to carry out nov

99 This method has the potential to simplify glycoprotein analysis by integrating glycan seq

100 This on-chip detection simplifies GP imaging as sophisticated s-SNOM detection

101 le for the activity, which can in turn yield simplified hERG toxicophores.

102 CrossCheck dramatically simplifies high-throughput screen data analysis and enab

103 ile the incorporated IC was analyzed using a simplified horseradish peroxidase enzyme-based colorimet

104 ose a standard means of orienting the PAM to simplify how its location and sequence are communicated.

105 accines, in part because of the potential to simplify how vaccines are made and facilitate a rapid re

106 Analyses of satellite data (1979-2014) and a simplified ice-upper ocean coupled model reveal that div

107 l structure with existing methods, but has a simplified implementation.

108 description of temporal networks is usually simplified in terms of their dynamic community structure

109 cysteine-mediated expressed protein ligation simplifies incorporation of post-translational modificat

110 GMM method offers an alternative to the over-simplified infinitesimal model in computer simulation as

111 NemoProfile simplifies instance collection by resolving memory overh

112 e method, we evaluated its performance for a simplified instrumentation.

113 nces into overlapping fragments along with a simplified integrative energy function for transcription

114 ng in the new pentamer approach along with a simplified integrative energy function improved transcri

115 ured by bottom-up mass spectrometry (HX MS), simplifies interpretation, and facilitates clear communi

116 approaches have recently been proposed that simplify interpretation of experimental DCs, by entirely

117 To simplify interpretation of nanodisc spectra, we engineer

118 In short, the results can be simplified into two models: (1) the rate-limiting step i

119 f halogenated compounds based on combining a simplified isotope pattern and mass defect cluster analy

120 ng of tetra- to heptachlorinated OH-CTTs and simplified it by countercurrent chromatography (CCC).

121 A simplified kinetic Monte Carlo model is presented to fol

122 ophobic dendritic block, which significantly simplifies kinetic analyses.

123 protein 1 and immunoglobulin M) has greatly simplified laboratory-based dengue diagnosis.

124 to-use Reagent System (BEARS) technology for simplified, low cost protein and peptide immunoprecipita

125 h that enables dynamic, highly efficient and simplified magnetic bead actuation for DNA analysis in a

126 DOACs offer simplified management of selected patients, as illustrat

127 parameters allowed access to a considerably simplified mathematical correlation of substrate and cat

128 Simplified mechanistic models in ecology have been criti

129 patients prone to primary nonadherence, and simplify medication regimens to maximize adherence and q

130 A simplified method for leukocyte characterization using s

131 coupling, in a one-pot procedure, provides a simplified method to access heterocycles without workup

132 Here we report a simplified method to purify and amplify DNA from complex

133 A simplified methodology to acquire steady-state emission

134 provides several examples illustrating that simplified methods may lead to less accurate or even mis

135 the cerebellum is a valid reference region, simplified methods seem to provide robust alternatives f

136 urther exploit the advantages of aptamers, a simplified mix and read assay was also developed.

137 The current research's simplified model (3 reactions, 17 constants) represented

138 and total bilirubin level were included in a simplified model and incorporated into the score.

139 This simplified model identifies individual-level dynamics-in

140 3-ethylhexyl-4-fluorothiophene) (F-P3EHT) as simplified model materials, using single-molecule/aggreg

141 We describe a simplified model of causal inference in multisensory spe

142 romogranin A-expressing COS7 cells used as a simplified model of induced secretion.

143 basic units of protein matrix of teeth) as a simplified model of teeth to explore the color source at

144 Using amorphous ZnO as a simplified model system, we show that the hydrogens pair

145 Similar concepts and simplifying modeling approaches may help elucidate the m

146 g computations in neural circuits often uses simplified models because the actual neuronal implementa

147 and animal cell plasma membranes, we studied simplified models, namely four-component lipid bilayer m

148 eral understanding of leaf design, and would simplify models of annual leaf carbon relations.

149 tudy seeks to increase device efficiency and simplify morphology measurements by replacing the typica

150 Our study further shows that simplifying multiple alternative models into a smaller n

151 ss its own CRISPR RNA (crRNA) can be used to simplify multiplexed genome editing.

152 lacking part of C-terminal domains leads to simplified neuronal arborization.

153 To assess the validity of a novel, simplified, noninvasive test for strabismus using video

154 te that neither the traditionally conceived "simplified" nor "complex" agricultural landscape is most

155 Two structurally simplified nucleobase analogues (1 and 4) lacking both t

156 Simplified numerical models show that the reduction kine

157 This new capability is used to simplify offset frequency measurements of a mode-locked

158 The indirect sensing system is further simplified on a multilayer membrane device that consists

159 xtra buffer loading step, which results in a simplified operation and reduced time of analysis compar

160 Android application software ("app") further simplifies operation for unskilled users.

161 ne status and gingivitis was conducted using simplified oral hygiene and modified Community Periodont

162 sized visuomotor processes in the context of simplified orienting movements in controlled laboratory

163 ecent meta-analysis approaches, however, are simplifying our understanding of how p53 functions as a

164 Finally, simplified outcome measures were calculated as ratio, wi

165 s windows of tuning parameter values thereby simplifying outlier detection and providing improved det

166 ing and signal processing functions, thereby simplifying overall system design.

167 ties along the root-stem-leaf continuum will simplify parameterization.

168 Thus, a highly simplified pectic primary cell wall regulates its own sy

169 dly, further studies will add layers to this simplified picture.

170 ation and validation cohorts, and assigned a simplified point-scoring system.

171 compressive sensing techniques with greatly simplified post processing, resulting in significantly f

172 Contrary to the simplifying premise of strict homeostasis in microbial d

173 ether reliable MPA values can be obtained by simplified procedures.

174 er support were developed that significantly simplify product purification and the transfer agent rec

175 To develop and externally validate a simplified prognostic score for ICC and to determine per

176 mino acids perform powerful ability for both simplifying protein complexity and identifying functiona

177 We evaluated the BYG Carba v2.0 using a simplified protocol, which detects CPE in less than 30 m

178 The highly simplified protocols and enhanced sensor performance mak

179 ittle knowledge exists about appropriate and simplified protocols for routine MS-based analysis of th

180 oligosaccharides are subjected to a greatly simplified purification scheme followed by structural re

181 core substituents prevent excess thionation, simplifying purification procedures.

182 can be used to engineer cell functionality, simplify quality assessment, and enhance manufacturabili

183 otein and a nuclear localization sequence to simplify quantitative nuclear fluorescence signal.

184 electrical control and coupling schemes that simplify qubit fabrication and operation.

185 as equivalent imaging properties but greatly simplified radiolabeling compared with other (68)Ga-PSMA

186 The BYG Carba v2.0 is a new highly simplified, rapid and accurate electrochemical assay dis

187 he use of transition state theory, even with simplified reaction coordinates, provides a good theoret

188 To mitigate safety concerns and simplify reaction execution, an HF-free protocol was dev

189 stor reconstruction methods can only process simplified real genome datasets or simulated datasets wi

190 potentials (BPNDs) were calculated using the simplified reference tissue model (SRTM) and SRTM2; the

191 isplaceable binding potential (BPND) using a simplified reference tissue model (SRTM) with distributi

192 rebellum as reference region, we applied the simplified reference tissue model 2 and Logan reference

193 The simplified reference tissue model 2 and the multilinear

194 ng potential (BPND) by multilinear analysis, simplified reference tissue model 2, and multilinear ref

195 SERT-rich structures and fit to 2 models: a simplified reference tissue model and a multilinear grap

196 and with noninvasive tracer kinetic methods (simplified reference tissue model and multilinear refere

197 OMADAM binding potential calculated from the simplified reference tissue model and the multilinear gr

198 = 0.01 + 1.00.BPND [full], R(2) = 0.97; for simplified reference tissue model, BPND [dual-window] =

199 The use of these simplified regimens has the potential to increase access

200 Simplified regimens with reduced pill burden and fewer s

201 methods, and technological applications for simplifying regimens and enhancing adherence, and 4 area

202 nsfer models of contrasting complexity and a simplified representation of the potential intensificati

203 how that the exertion of tensile forces on a simplified retinal chromophore model provokes a substant

204 suitable for next-generation sequencing, and simplifies retooling targeted resequencing pipelines to

205 nge of substrate classes, and the ability to simplify retrosynthetic analysis is exemplified with the

206 The model was converted into a simplified risk scoring system and was externally valida

207 etically susceptible characteristics greatly simplified sample handling procedures.

208 id-phase providing unique advantages such as simplified sample preparation, improved yield, and high

209 with magnetic bead extraction, which greatly simplifies sample handling procedures.

210 A simplified scheme is proposed for samples requiring the

211 A simplified score that excluded BV and candidiasis yielde

212 Women with simplified scores >6 accounted for 16% of the population

213 This calculator may simplify SD OCT grading and with future validation has a

214 ecision medicine, but many studies today use simplified semiquantitative methods without properly val

215 The AREDS simplified severity scale classified late AMD risk level

216 te the Age-Related Eye Disease Study (AREDS) simplified severity scale in Asians.

217 The AREDS simplified severity scale is useful in predicting the ri

218 ed signal enhancement will allow technically simplified signal detection, paving the way for single m

219 rison of the attenuation factor (beta of the simplified Simmons equation) across these SAMs with the

220 the final cell mass by a factor of 1.3, thus simplifying solid-liquid separation.

221 ize norms likely evolved in our ancestors to simplify solving certain challenges-including social one

222 ntify ERbeta expression is the Ki However, a simplified static imaging protocol for determining the S

223 d brain uptake of (18)F-AV45 assessed by the simplified static SUVR protocol does not truly reflect A

224 easy to manufacture in a stable form, which simplifies storage and reduces cost.

225 ar idempotent cloning, it is unclear if such simplified strategies scale to very large constructs for

226 Here we present three packages which aim to simplify such procedures.

227 This could simplify surface code networks which require spatially c

228 ovnikov oxidation of alkene feedstocks could simplify synthetic routes to many important molecules an

229 Building this simplified system led to the discovery of essential role

230 ission yeast actin cytoskeleton is an ideal, simplified system to investigate fundamental mechanisms

231 ure of basal actomyosin mechanodynamics in a simplified system, allowing us to infer how the presence

232 s, and only the labeled protein is released, simplifying target protein purification and labeling to

233 In an effort to improve test performance and simplify testing in early LD, we evaluated several modif

234 PI-1), we eliminated internal regulation and simplified the genetics by removing or recoding genes, s

235 length from 4 to 35 amino acids, and greatly simplified the synthesis of cyclic peptides.

236 used to modify baculovirus vectors-which has simplified the system-and transform insect cells, which

237 The closed-tube format of the assay simplified the workflow and minimized carryover contamin

238 given in a symmetric form, an extension that simplifies the application of the theory to experiments.

239 -treatment steps are required, which greatly simplifies the biosensor system.

240 This integration simplifies the conventional combination of SPR and QCM a

241 This powerful methodology dramatically simplifies the design of acoustic devices and provides a

242 The removal of physical gates significantly simplifies the device architecture and enables photolith

243 This hybrid approach simplifies the experiment and increases the data acquisi

244 stant offers a Graphical User Interface that simplifies the interaction between the user and the tool

245 lence between bilayers and curved monolayers simplifies the inverse problem considerably by providing

246 This simplifies the prediction and allows for improved accura

247 Hence, the tGBS protocol simplifies the preparation of high-quality GBS sequencin

248 treptavidin (SAv) roadblocking strategy that simplifies the preparation of roadblocking DNA templates

249 This template/catalyst-free approach greatly simplifies the synthesis procedure compared to conventio

250 It aims to fully encompass and simplify the "raw data-to-publication" pathway and make

251 automated coupling-method was developed, to simplify the alignment of the FERS setup.

252 ady-to-use (shelf-ready) reagents to greatly simplify the bioanalysis procedures, allowing the assay

253 lusion of symptomatic lesions is expected to simplify the clinical use of MRI criteria without reduci

254 and analytic methods have been developed to simplify the diagnosis of glaucoma and the interpretatio

255 g "compression heuristics", or schemata that simplify the encoding and recall of social information.

256 itu catalysts on the carbon fiber support to simplify the fabrication process for catalytic electrode

257 as promising alternative to PCR and greatly simplify the implementation of amplification methods in

258 ults of the higher levels of the ATC code to simplify the predictions of the lower levels.

259 closure devices are in development that may simplify the procedure and reduce bleeding.

260 ues for lymphatic mapping attempt to further simplify the procedure.

261 To simplify the process of mapping new mutations, we develo

262 pic and analytical techniques to improve and simplify the process of metabolite identification.

263 Glycan Reader was originally developed to simplify the reading of Protein Data Bank (PDB) files co

264 for structure prediction and design, as they simplify the RNA structure to reduce the conformational

265 s underlie the hierarchy of 30S assembly and simplify the search for the native ribosome structure.Ri

266 To simplify the selection of sgSTOPs, our resource includes

267 units over weeks of recording, dramatically simplifying the analysis of large datasets.

268 ents in efficiency while limiting damage and simplifying the delivery of editing machinery.

269 This allowed substantial simplifying the transistors manufacturing.

270 ity due to multiple inefficient steps, while simplifying the workflow to enhance sensitivity and crea

271 e synthesizing large biochemical systems and simplifying their assembly.

272 ize of mutagenic plasmids and simultaneously simplifying their design.

273 sible region has been recently realized by a simplified theory.

274 Here we introduce a package that is aimed to simplify this process.

275 that the complex mixture of (3)CDOM* can be simplified to a single signal.

276 ry extraction of ellagitannins from wine was simplified to a single step of solid phase extraction (S

277 ous bed or multiple parallel pipes cannot be simplified to flow through one orifice with a certain di

278 native structures of phenolic compounds were simplified to its monomers allowing quantification and s

279 the perspective of plant and fungal origin, simplified to the least complex representations or 'moti

280 By considering a simplified tractable model, we identify different homolo

281 Thus, a method is presented by which to use simplified training molecules and resulting correlations

282 isualizing the distribution of sites along a simplified transcript model.

283 a system is of fundamental interest and may simplify transport experiments.

284 explosive compounds to protect soldiers and simplify transport logistics.

285 (450 mg/day) has the potential to provide a simplified treatment for HCV that is effective and well

286 These findings could help simplify treatment algorithms and reduce treatment burde

287 Improved drug regimens to shorten and simplify treatment are urgently required, however a majo

288 aroxaban, an oral factor Xa inhibitor, might simplify treatment compared with fondaparinux because it

289 such an outcome with a single molecule would simplify treatment regimes.

290 A simplified two-dimensional numerical modeling shows that

291 Simplified ultrafiltration devices permit fluid removal

292 The delivery vehicle can be further simplified utilizing injectable polymeric nanocarriers c

293 ergy allocation that is closely related to a simplified version of Dynamic Energy Budget theory, DEBk

294 A simplified version of the frontier orbital model for a n

295 ndent sample of PD patients (n = 20) using a simplified version of the task.

296 on current niche models, which encode a very simplified view of plant communities, suggesting that th

297 the protein complexity can be significantly simplified, which leads to decrease chance of overfittin

298 The flutter driven-TENGs are deposited on simplified wing designs to match the electrical performa

299 lytes with standard instrumentation, thereby simplifying workflows in studies of cell-signaling casca

300 t underlie this process lays the basis for a simplified yet functional IL-12 cytokine.