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1 andard influenza vaccination consisting of a single dose.
2 vided significantly better protection than a single dose.
3 after transplantation and was effective as a single dose.
4 /2013 pLAIV, while older subjects received a single dose.
5 into a solution and administered orally in a single dose.
6 rived master donor viruses and licensed as a single dose.
7 and drug efficacy for almost 3 weeks after a single dose.
8 lethal anthrax spore infection in mice as a single dose.
9 ection against lethal H5N1 infection after a single dose.
10 ger lasting than that of BCG when given as a single dose.
13 l indometacin group, all patients received a single dose (100 mg) of rectal indometacin within 30 min
15 trols, 7 d for single-dose GMX1778, 28 d for single-dose (177)Lu-DOTATATE, 35 d for 3 weekly doses of
16 oligonucleotide targeting ANGPTL3 mRNA in a single dose (20, 40, or 80 mg) or multiple doses (10, 20
17 and completely protects mice when given as a single dose 24 h before or after challenge with influenz
18 A(H1N1)pdm09-infected ferrets receiving a single dose (25 mg/kg) had reduced viral titers and show
19 e for enhancing the protective efficacy of a single dose adenovirus-vectored malaria vaccine in a mou
20 e develop a rapid-response, fully synthetic, single-dose, adjuvant-free dendrimer nanoparticle vaccin
21 etic data for 16 was generated in mouse with single dose administration showing favorable oral bioava
25 nic in this vulnerable population and that a single dose alone may be sufficient to achieve similar s
26 ho-AKT (S473) in CLL tumor cells following a single dose and near-complete inhibition of CLL prolifer
27 EBOV was reactogenic but immunogenic after a single dose and warrants further evaluation for safety a
28 ed clinical trial to compare the efficacy of single-dose and 3-dose regimens of BPG for the treatment
29 subjects) and 93% (27 of 29 subjects) in the single-dose and 3-dose regimens, respectively (absolute
30 ss rates were 93% (27 of 29) and 100% in the single-dose and 3-dose regimens, respectively (absolute
33 even overlooked if they are measured after a single dose, and that repeated administrations are neces
34 xenografts were randomized to receive either single-dose antiangiogenic treatment (bevacizumab, n = 1
36 t responses or specific IgE levels, but this single-dose approach has not yet been validated for risk
37 t-booster responses in infants primed with a single dose are equivalent or superior to those seen fol
38 SJSA-1 xenograft model even when given as a single dose as demonstrated for 4-[(3S,3'S,3'aS,5'R,6'aS
39 o at a dose of 10 mg/kg, administered as one single dose at the start of days 1, 22, 43, and 64-ie, f
41 watery diarrhea were randomized and received single-dose azithromycin (500 mg; 106 persons), levoflox
44 basis of decline in serological titre, oral single-dose azithromycin was effective in participants w
46 that continuous bioaugmentation (rather than single-dose bioaugmentation) would be required to improv
54 he efficacy, safety, and pharmacokinetics of single-dose DEC, IVM, and ALB in Wuchereria bancrofti-in
57 period receiving one inhalation per day via single-dose dry-powder inhaler of open-label 18 mug tiot
59 ry metastatic cancer who were treated with a single dose each (concomitantly) of the immune checkpoin
60 ey rats were administered a combination of a single dose each of plastic microspheres and vascular en
61 past epidemics are based on severely limited single-dose efficacy data and may not fully capture unce
62 ilizer (control) (MIN) or cattle manure at a single dose equivalent to potassium fertilizer (ORG) or
65 each pair receiving one of five pre-assigned single doses from 0.04 x 106 to 1.5 x 106 IU/m2, in orde
66 than at day 0) was 3 d for controls, 7 d for single-dose GMX1778, 28 d for single-dose (177)Lu-DOTATA
70 f the study relates to the assumption that a single dose, if administered quickly, will induce a simi
74 cy following intratracheal instillation of a single dose in a Lewis lung carcinoma model in mice.
75 and sustained antidepressant effects after a single dose in patients with depression, but its use is
76 nary oxalate concentration up to 50% after a single dose in the genetic mouse model of PH1, and up to
80 ind, placebo-controlled crossover study with single-dose intranasal oxytocin (24 IU) in ten overweigh
86 adequacy of PEG preparation with addition of single dose LB (24mcg) vs placebo and efficacy of reduce
89 eceive vaccinations at 0, 4, and 8 weeks via single-dose needle and syringe injection in one deltoid
90 cells per cubic millimeter to zidovudine and single-dose nevirapine plus a 1-to-2-week postpartum "ta
91 herapy (ART) as compared with zidovudine and single-dose nevirapine to prevent transmission of the hu
95 y; range, 43-87 y) with mCRPC who received a single dose of (177)Lu-PSMA-617 (mean, 5.9 +/- 0.5 GBq)
96 aluate the response to and tolerability of a single dose of (177)Lu-PSMA-617 in a large cohort of pat
98 n unmasked health-care worker; or received a single dose of (4) inactivated influenza vaccine by micr
101 del of periprosthetic osteomyelitis, where a single dose of 10 mg/kg (15.6 mumol/kg) conjugate reduce
102 nmol/L) were randomly assigned to receive a single dose of 10-120 mg IONIS-APO(a)LRx subcutaneously
106 lians in the nested trial (1:1) to receive a single dose of 2 x 10(8) plaque-forming units of MVA-BN-
108 h a predicted half-life of 36 h in humans, a single dose of 260 mg might be sufficient to maintain th
109 and stage-1 hypertensive patients received a single dose of 30 mL of FVOO (OOPC=961 mg/kg) or VOO (OO
114 2 weeks or 5 months after vaccination, and a single dose of 50 mug was sufficient to protect non-huma
115 1 ratio to receive fremanezumab quarterly (a single dose of 675 mg at baseline and placebo at weeks 4
116 in three BDIV and two BDIX rats exposed to a single dose of 80 mg ENU/kg body weight on postnatal day
118 ing alpha9beta1/alpha4beta1 integrins with a single dose of a small molecule antagonist (BOP (N-(benz
119 cies and neurofibrillary tangles following a single dose of AAV-vectored PHF1 compared with mice trea
121 (1.3 x 1012GC), and the mice that received a single dose of AAV9-EF1a-NPC1 at weaning (1.2 x 1012GC),
122 article, we demonstrate mice treated with a single dose of abatacept 8 h post SEB exposure had reduc
123 ized to receive either 4 repeated doses or a single dose of albendazole and were followed up during 1
124 f fluconazole, 5 days of azithromycin, and a single dose of albendazole, as compared with standard pr
126 ntrolled crossover study of the effects of a single dose of amphetamine (10 mg po) on PPI and MATRICS
129 ood was drawn before and 28 days following a single dose of bivalent HPV vaccine (2vHPV; Cervarix, Gl
130 e Control and Prevention recommendation of a single dose of BPG in HIV-infected patients with early s
133 The magnitude of hsCRP reduction following a single dose of canakinumab might provide a simple clinic
140 of BALB/c or C57BL/6 recipients and given a single dose of CTLA4-Fc at the time of transplant and 4d
141 or human liver antigens, were treated with a single dose of depleting mouse anti-CD20 antibody at the
144 atio to receive vitamin K concomitant with a single dose of either 4F-PCC (Beriplex/Kcentra/Confidex;
146 enerated randomisation sequence to receive a single dose of either mIPV2HD or standard trivalent IPV
150 ed proctitis, the prophylactic delivery of a single dose of GAG from a SELP matrix administered prior
154 ection discontinued study medication after a single dose of grazoprevir, ruzasvir, and uprifosbuvir p
157 gned (1:1:1:1) to four groups and received a single dose of inactivated influenza vaccine (fluvirin:
158 holesterol levels were 27.9 to 41.9% after a single dose of inclisiran and 35.5 to 52.6% after two do
159 009 H1N1 pandemic influenza vaccines after a single dose of intradermal, but not intramuscular, immun
165 ng pacemaker variables in conjunction with a single dose of ivabradine does not adversely affect exer
166 etreated by intraperitoneal injection with a single dose of ketamine (1, 3, 10, 30 and 80 mg kg(-1)),
171 ts were imaged following administration of a single dose of MDPV (0.3, 1.0, or 3.0 mg/kg) or saline.
172 , DM-MEL, and EP-DM-MEL) were treated with a single dose of melatonin (10 mg/body weight) every day f
173 ges in vivo and in vitro were prevented by a single dose of MitoQ bound to nanoparticles, which were
175 tify the highest, well-tolerated, and safest single dose of multipotent adult progenitor cells, and i
178 design we aimed to determine the effect of a single dose of nalmefene on striatal blood oxygen level-
181 idence from previous studies suggests that a single dose of oral cholera vaccine might provide substa
182 s engaged in the first field deployment of a single dose of oral cholera vaccine to enhance the outbr
183 ng to primary care with acute sore throat, a single dose of oral dexamethasone compared with placebo
186 Syphilis is the best example, for which a single dose of penicillin (which literally costs pennies
187 rative Cross (CC) were orally administered a single dose of PERC (1,000 mg/kg) or vehicle (Alkamuls-E
189 d no additive antiviral effect compared to a single dose of PGT121, potentially reflecting the nearly
190 Patients were randomly assigned to receive a single dose of placebo or 200, 300, or 500 mg of inclisi
194 pharmacokinetics, and antiviral effect of a single dose of RG-101, a hepatocyte targeted N-acetylgal
198 ing (CFC) paradigm, mice were administered a single dose of saline or ketamine (30 mg/kg) at varying
207 ecially those with infant contact, receive a single dose of Tdap (tetanus toxoid, reduced diphtheria
208 mimic males, female mice were administered a single dose of testosterone as neonates or as adults bef
209 ively, our findings show how administering a single dose of TGFbeta prior to oncolytic virus treatmen
210 vo Vaccination studies in mice showed that a single dose of the B/Bris att candidate stimulated steri
211 In this phase 1 study, we administered a single dose of the chimpanzee adenovirus 3 (ChAd3) vacci
212 ed with the 1986 virus and vaccinated with a single dose of the COBRA HA VLP vaccines elicited antibo
217 f simulated menses; mice were treated with a single dose of the nonaromatizable androgen dihydrotesto
218 jection, mdx muscles were pre-treated with a single dose of the peptide-phosphorodiamidate morpholino
220 human cellular immune responses induced by a single dose of the rVSV-ZEBOV vaccine candidate, which s
221 Hence, BALB/c mice were immunized with a single dose of the three proteins adjuvanted with CpG an
222 sociated disease; and speculates that even a single dose of these vaccines, when given to adolescents
223 Specifically, short-term treatment with a single dose of torin 1 significantly increased vector-me
224 mtansine-resistant breast cancer (JIMT-1), a single dose of trastuzumab-Lx-AF outperformed its maleim
225 alation design (n = 25), patients received a single dose of varlilumab (0.1, 0.3, 1.0, 3.0, or 10 mg/
226 were randomly assigned (1:1:1) to receive a single dose of Vi-conjugate (Vi-TT), Vi-polysaccharide (
227 children living in hyperendemic settings, a single dose of virosomal HAV vaccine is sufficient to ac
229 7BL/6 wild-type or CD73(-/-) mice received a single dose of whole thorax irradiation (WTI, 15 Gy).
230 ession in lungs 24 hours after exposure to a single dose of whole thorax lung irradiation sufficient
235 s after ischaemic stroke were implanted with single doses of 2 million, 5 million, 10 million, or 20
236 nding-dose cohort trial evaluated avoralstat single doses of 50, 125, 250, 500, and 1000 mg and multi
238 lotinib alone, (ii) sequentially alternating single doses of each drug leads to minimal tumor burden
239 inical staff did randomisation) to different single doses of intramuscular immunisation with ChAd3-EB
241 ) model to test the antimalarial activity of single doses of piperaquine (960, 640, and 480 mg) in 3
243 the pharmacokinetics and pharmacodynamics of single doses of subcutaneous aldesleukin in the Adaptive
245 h subject was randomized to receive either a single-dose of 2,000 FU NK (NSK-SD, Japan Bio Science La
247 ng iron supplements on alternate days and in single doses optimises iron absorption and might be a pr
249 with antibiotics in the POCT group received single doses or brief courses of antibiotics (<48 h) com
250 ll, more patients in the POCT group received single doses or brief courses of antibiotics than did pa
251 ntibiotics, proportion of patients receiving single doses or brief courses of antibiotics, length of
253 gent adverse events occurred in 20.1% of the single-dose patients and 19.9% on the 2-dose regimen.
263 Future studies should assess the safety of single-dose primaquine in G6PD-deficient individuals to
264 Assuming biannual mass vaccination with a single-dose primary course, vaccine history was calculat
265 Our results demonstrate selectable and near-single-dose production of these biologics in <24 h with
266 KV vaccine based on the NS1 protein and (ii) single dose protection against ZIKV using an immunocompe
267 V E2/E1 glycoproteins also provided durable, single-dose protection from lethal VEEV and EEEV challen
268 tivation may facilitate the development of a single-dose RABV vaccine that replaces current complicat
270 - and two-dose efficacy, we projected that a single-dose reactive campaign could have prevented 70,58
272 nt the first public health use of a reduced, single-dose regimen of oral cholera vaccine, and show th
274 ith high-dose azithromycin, effectiveness of single-dose rifaximin, and emerging resistance to front-
276 for dose-dense PTX chemotherapy with active single doses, showing the relative additional contributi
279 d Products in People With Epilepsy (EQUIGEN) single-dose study is a crossover, prospective, sequence-
280 TX from Dark Agouti into Lewis rats applying single-dose tacrolimus (TAC) at varying concentrations.
281 Usually, trichomoniasis can be cured with single-dose therapy of an appropriate nitroimidazole ant
282 mmunologic reactions were compared following single-dose therapy with DEC or IVM to assess whether th
287 long half-life suggests a possible use in a single-dose treatment in combination with other drugs.
288 fferences in pain reduction at 2 hours among single-dose treatment with ibuprofen and acetaminophen o
296 accine and vaccine uptake for 2-dose MCV and single-dose varicella vaccine, focusing on timeliness.
297 a (MMR) vaccination coverage with at least a single dose was estimated to be 14% in affected Amish ho
300 nificantly blunted after chronic compared to single dosing with either ICS/IND (P<.005) or ICS/IND/TI
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